Journal articles: 'Male genital diseases'

1

Jacob, Jesse T., Minh Ly T. Nguyen, and Susan M. Ray. "Male genital tuberculosis." Lancet Infectious Diseases 8, no. 5 (May 2008): 335–42. http://dx.doi.org/10.1016/s1473-3099(08)70101-4.

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Mallon, E., J. S. Ross, D. A. Hawkins, M. Dinneen, N. Francis, and C. B. Bunker. "Biopsy of male genital dermatosis." Sexually Transmitted Infections 73, no. 5 (October 1, 1997): 421. http://dx.doi.org/10.1136/sti.73.5.421-a.

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Oriel, J. D. "Male genital Chlamydia trachomatis infections." Journal of Infection 25 (July 1992): 35–37. http://dx.doi.org/10.1016/0163-4453(92)91944-7.

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Shim, T. N., D. Hawkins, A. Muneer, S. Minhas, A. Freeman, C. Jameson, N. Francis, M. Dinneen, and C. B. Bunker. "P2.182 Male Genital Dermatoses in HIV." Sexually Transmitted Infections 89, Suppl 1 (July 2013): A143.2—A143. http://dx.doi.org/10.1136/sextrans-2013-051184.0446.

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Patil C, Sridevi, Sharanbasava V, and P. S. Suman Babu. "A clinico-epidemiological study of non venereal dermatoses involving male and female genitalia." IP Indian Journal of Clinical and Experimental Dermatology 7, no. 3 (September 15, 2021): 237–42. http://dx.doi.org/10.18231/j.ijced.2021.045.

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Non venereal genital lesions may be confused with venereal diseases. This may be responsible for considerable concern to patients and may cause diagnostic dilemma to the physicians. This study was conducted to find out the hospital based prevalence and clinical profile of Non venereal dermatoses involving male and female Genitalia with or without associated lesions elsewhere.It was a descriptive study which included a series of 120 patients presenting to Dermatology department from Jan 2015 to July 2016 with non-venereal genital lesions.Among 120 patients, there were 109 males and 11 females (M:F 9.9:1). The prevalence of non-venereal genital lesion was 21.76 per 10,000 patients. The age ranged from 2 months to 65 years with the mean age of 32.94 years and majority in the age group of 21-30 years(25%). The most common disorder was fixed drug eruptions ,37 (30.83%) followed by vitiligo, 29 (24.16%) and psoriasis, 13 (10.83%). This study highlights the importance of diagnosing common non venereal genital dermatoses. It also helps in avoiding the general misconception that all genital lesions are sexually transmitted.

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Rao, A., and C. B. Bunker. "Male genital skin biopsy." International Journal of STD & AIDS 22, no. 7 (July 2011): 418–19. http://dx.doi.org/10.1258/ijsa.2011.011072.

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Mazzoni, Daniel, David Winkle, Louis Pool, Anthony Hall, and Jim Muir. "Genital premalignant and malignant diseases: a retrospective study of male genital skin biopsies." International Journal of Dermatology 60, no. 6 (February 27, 2021): 712–16. http://dx.doi.org/10.1111/ijd.15439.

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P., Mamatha, Abhijeet Vardhan, and Sheena Arora. "Incidence of non-venereal lesions of the male genitalia: a study of 248 male cases at a tertiary care centre." International Journal of Research in Dermatology 6, no. 2 (February 24, 2020): 187. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20200472.

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Background: Non-venereal dermatoses of external genitalia refers to those dermatoses involving external genitalia which are not sexually transmitted. These are associated with mental distress and guilt feelings in affected patients. The aim was to study the incidence of non-venereal lesions of the genitalia.Methods: This was a cross-sectional clinical observational study in 248 male patients attending dermatovenereology OPD of Vydehi Institute of Medical Sciences and Research Center with non-venereal genital lesions for a period of 18 months. Cases having venereal diseases were excluded from the study.Results: The study included 248 male patients with non-venereal genital lesions. A total of twenty-five different types of non-venereal dermatoses were noted in our study. The most common non-venereal dermatoses were Non-venereal infections, seen in 107 patients (43.14%), which includes scabies in 45 patients (18.14%), tinea cruris 25 patients (11.29%), candidiasis 28 (11.29%) followed by lichen simplex chronicus 23 cases (9.27%) and scrotal dermatitis (6.45%) other dermatoses include psoriasis, lichen planus, fixed drug eruptions, scrotal horn, histoid hansens, squamous cell carcinoma, Zoon’s balanitis.Conclusions: This study reflected the importance of diagnosis of non-Venereal dermatoses and refutes the general misconception that all genital lesions are of venereal origin.

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Ramoni, Stefano, Susanna Benardon, Cristina Beatrice Spigariolo, Luciano Süss, and Stefano Veraldi. "Ticks on the external male genital structures." Parasitology International 83 (August 2021): 102336. http://dx.doi.org/10.1016/j.parint.2021.102336.

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Bachaspatimayum, Romita, Zamzachin Guite, and Thangjam Bijayanti Devi. "Clinical and laboratory profiles of genital ulcers (sexually transmitted diseases) in a tertiary care center in northeastern India." Our Dermatology Online 12, no. 2 (April 1, 2021): 120–29. http://dx.doi.org/10.7241/ourd.20212.4.

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Background: Genital ulcers are defined as breaches in the continuity of the genital mucosa and/or skin. Sexually transmitted infections (STIs) that cause genital ulcer disease (GUD) are syphilis, chancroid, donovanosis, lymphogranuloma venereum (LGV), and herpes genitalis. This study aimed to investigate the clinical and laboratory profiles of STI-related genital ulcers. Materials and Methods: A cross-sectional two-year study was conducted on patients attending the Outpatient Department of Dermatology, Venereology and Leprosy in a tertiary care center in northeastern India. Selected were 95 patients who presented themselves with STI-related genital ulcers. Detailed history taking and examination were conducted with basic tests to assist the diagnosis. Results: The male-to-female ratio was 3.32:1, and the most common site was the glans and prepuce in males (28.77%) and the labia majora and minora in females (36.36%). 96.84% of patients had superficial ulcers. The KOH mount was positive in 26 patients. The Tzanck smear was positive in 31 patients. RPR was positive in four. HIV was positive in eleven. Herpes genitalis (96.84%) was the most common GUD. Mixed STIs were attested in 41.05% of patients. Conclusion: GUD can take various forms of presentation. The available laboratory tests should be utilized. The possibility of mixed infections should always be kept in mind.

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Nyat, Asha, Arti Singh, Alpana Mohta, Ramesh Kumar Kushwaha, Devanshi Gupta, and Suresh Kumar Jain. "A study of the pattern of non-venereal genital dermatoses in male patients at a Tertiary Care Centre from Hadoti region of Rajasthan, India." Our Dermatology Online 12, e (September 18, 2021): e87-e87. http://dx.doi.org/10.7241/ourd.2021e.87.

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Background: Non venereological diseases of genitalia can be a diagnostic dilemma to a dermatologist and also a cause of considerable concern to the patient because they tend to get misdiagnosed with venereal diseases. Aims: To study the pattern and clinico-epidemiological profile of non-venereal dermatoses of male genitalia in Hadoti region of Rajasthan. Materials and Methods: We conducted this prospective, descriptive study in 250 male patients with non venereal dermatoses in Rajasthan from January 2015 to July 2016. The demographic profile and clinical findings of the patients were recorded and appropriate investigations and histopathological examination were done as and when required. Cases having venereal diseases were excluded from the study by clinical examination, serological and microbiological tests for venereal diseases. Results: The age of the patients ranged between one to 70 years, with mean age being 27.1 years. The most common dermatosis was nodular scabies 54 (21.6%) followed by sebocystoma multiplex 24 (9.6%), fixed drug eruption 19 (7.6%), tinea genitalis 17 (6.8%) and genital psoriasis 14 (5.6%) cases. Conclusion: This study highlights the importance of diagnosing non-venereal dermatoses for both correct treatment of the patient as well as to alleviate the anxiety associated with venereophobia and cancer phobia.

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Witkin, Steven S., Jan Jeremias, Ann Marie Bongiovanni, and M. Gladys Munoz. "Immune regulation in the male genital tract." Infectious Diseases in Obstetrics and Gynecology 4, no. 3 (1996): 131–35. http://dx.doi.org/10.1002/(sici)1098-0997(1996)4:3<131::aid-idog5>3.0.co;2-3.

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Hogade, Ashok S., and Shantanu Mishra. "A study of pattern of nonvenereal genital dermatoses of male attending skin OPD of tertiary centre in Kalaburagi." International Journal of Research in Dermatology 3, no. 3 (August 24, 2017): 407. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20173922.

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Background: Dermatoses involving genital areas are not always sexually transmitted. The diseases, which are not sexually transmitted, are referred as nonvenereal dermatoses. These disorders are the cause of considerable concern to patients causing mental distress and guilt feeling in them. Nonvenereal dermatoses are quiet often a diagnostic dilemma to the treating physician also. The aim was to determine clinical and epidemiological pattern of nonvenereal dermatoses of male external genitalia.Methods: This was a descriptive study of 50 consecutive male patients over age of 18 years, with genital lesions of nonvenereal origin, attending the skin outpatient department of BTGH, Kalaburagi. Study was done for a period of 6 months.Results: The study included 50 male patients with nonvenereal genital lesions. A total of 14 nonvenereal genital dermatoses were noted. The most common nonvenereal genital dermatoses were vitiligo (20%), fixed drug eruptions (16%), scabies (14%), pearly penile papule (10%), and dermatophytoses (10%). Other dermatoses included psoriasis, plasma cell balanitis or Zoon's balanitis, lichen simplex chronicus, lymphangioma circumscriptum, squamous cell carcinoma, scrotal dermatitis, lichen planus, steatocystoma multiplex and candidiasis.Conclusions:This study helps in understanding the etiological causes of nonvenereal genital dermatoses and their pattern in this region.

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Albero, Ginesa, Xavier Castellsagué, Anna R. Giuliano, and Francesc Xavier Bosch. "Male Circumcision and Genital Human Papillomavirus." Sexually Transmitted Diseases 39, no. 2 (February 2012): 104–13. http://dx.doi.org/10.1097/olq.0b013e3182387abd.

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Saxena, Snigdha, Sidharth Tandon, Kabir Sardana, and Sonali Bajaj. "Herpetiform aphthous genital ulcers misdiagnosed as herpes genitalis in a young male and their effective response to colchicine therapy." International Journal of STD & AIDS 30, no. 13 (November 2019): 1340–43. http://dx.doi.org/10.1177/0956462419870672.

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Genital ulceration can be a source of tremendous stress to the patient, as well as to the family members, and poses a difficult and sensitive diagnostic conundrum for the clinician. Cultural taboos and social stigmas related with the disease often result in the clinician not believing the patient’s version of history and basing the diagnosis entirely upon the clinical picture, aided by diagnostic tests. The clinicians should keep in mind that sexually transmitted infections (STIs), which can cause genital ulceration are very common, but there is a long list of non-sexually acquired causes of genital ulceration, which can lead to a diagnostic dilemma, and these should be considered before labelling the patient as suffering from a STI. We present a rare case of herpetiform genital aphthous ulcers mimicking herpes genitalis and chancroid, which was misdiagnosed repeatedly, and their effective response to treatment with colchicine on subsequent identification of the correct diagnosis.

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Sonda, L. Paul, and Stephen Wang. "Evaluation of Male External Genital Diseases in the Emergency Room Setting." Emergency Medicine Clinics of North America 6, no. 3 (August 1988): 473–86. http://dx.doi.org/10.1016/s0733-8627(20)30542-3.

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Malagón, Talía, Karolina Louvanto, Michel Wissing, Ann N. Burchell, Pierre-Paul Tellier, Mariam El-Zein, François Coutlée, and Eduardo L. Franco. "Hand-to-genital and genital-to-genital transmission of human papillomaviruses between male and female sexual partners (HITCH): a prospective cohort study." Lancet Infectious Diseases 19, no. 3 (March 2019): 317–26. http://dx.doi.org/10.1016/s1473-3099(18)30655-8.

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Strand, A., and E. Rylander. "Diagnosis of genital human papillomavirus lesions in the male." Sexually Transmitted Infections 70, no. 4 (August 1, 1994): 294. http://dx.doi.org/10.1136/sti.70.4.294.

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Steele, M. S. "Male genital hygiene beliefs and practices in Nairobi, Kenya." Sexually Transmitted Infections 80, no. 6 (December 1, 2004): 471–76. http://dx.doi.org/10.1136/sti.2004.010447.

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Mondaini, Nicola, Mauro Silvani, Teo Zenico, Fabrizio Gallo, Franco Rosso, Tommaso Cai, Gianni Ughi, Pasquale Scarano, Vincenzo Orlando, and Riccardo Bartoletti. "Genital diseases awareness in young male students: Is information necessary to protect them?" Archivio Italiano di Urologia e Andrologia 85, no. 1 (April 19, 2013): 14. http://dx.doi.org/10.4081/aiua.2013.1.14.

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Introduction: Few studies on the prevalence of male sexual diseases are currently available due to difficult application of observational studies or andrological disease prevention campaigns on large series of apparently healthy subjects. The medical check-up linked to compulsory military service represented in Italy a valid tool for epidemiological and observational study for 18 year old boys from 1861 to 2004. The stopping of compulsory military service and its related medical check-up could have determined an important social impact in terms of a lower level of attention and care on male genital/sexual diseases. The aim of the present observational study was to check the prevalence of genital/ sexual diseases among young male high-school students and promote an alternative campaign of information among young students. Methods: A prospective observational analytical study on young male students was conducted by 6 urological centres. Genital and sexually transmitted diseases were presented with slides to students in a general assembly. Some students were then counselled and filled out a short questionnaire on their lifestyle. Results: 12,535 students (10,432 males-83.6%) followed the presentation. and 4,897 males (46.7%) decided to be checked-up by the urologist and out of them 1554 (31.7%) presented relevant andrological diseases. Five-hundred students completed the questionnaire concerning their lifestyle. Many of them had not yet experienced condom use during sexual intercourse (27.8%). Drug abuse was reported by 39.6% of subjects and alcohol consumption in 80.8% of them. Conclusions: These data suggest the need for a national information campaign on male sexual disorders to promote sexual health.

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Zimba, Tomas Francisco, Teke Apalata, Willem Adrian Sturm, and Prashini Moodley. "Aetiology of sexually transmitted infections in Maputo, Mozambique." Journal of Infection in Developing Countries 5, no. 01 (September 16, 2010): 041–47. http://dx.doi.org/10.3855/jidc.1179.

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Introduction: The study sought to ascertain the prevalence of the aetiological agents of genital discharge and genital ulcer diseases in Maputo, Mozambique. Methodology: Consecutive consenting patients presenting to the Centro de Saúde do Porto in Maputo between March and April 2005 with genital discharge syndrome and/or genital ulcer diseases were recruited. Specimens were collected for the identification of STI pathogens. Results: Of 346 recruited patients, 164 were male and 182 female. The prevalence of confirmed single aetiological agents for male urethritis was as follows: N. gonorrhoeae, 35%; C. trachomatis, 10%; and M. genitalium 4%. For vaginal discharge, N. gonorrhoeae was found in11% of the women tested, followed by C. trachomatis (6.5%), bacterial vaginosis (34%), and T. vaginalis (2%). The prevalence of genital ulcers was as follows: Herpes simplex virus type 2, 62%; H. ducreyi 4 %; and C. trachomatis biovar LGV, 4%. Five percent of patients with genital ulcers had a positive syphilis serology (RPR ≥ 1:8 and confirmed by TPHA) and 35% of all tested patients were HIV-1/2 infected. Cases of mixed infections were present in 5%, 11% and 3% of patients with male urethritis, vaginal discharge, and genital ulcers respectively. Conclusion: The classic sexually transmitted infection aetiologies are still prevalent in Maputo. The study highlights the need for a periodic surveillance to inform syndromic management protocols.

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Mitra, Debdeep, Anuj Bhatnagar, Arun Kumar, and Manish Kumar. "Genital ulcers in a middle-aged male." Indian Journal of Sexually Transmitted Diseases and AIDS 44, no. 2 (2023): 191. http://dx.doi.org/10.4103/ijstd.ijstd_45_22.

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Gagneux-Brunon, Amandine, Nicolas Rochereau, Elisabeth Botelho-Nevers, Frédéric Lucht, Bruno Pozzetto, Stéphane Paul, and Thomas Bourlet. "Humoral responses against HIV in male genital tract." AIDS 31, no. 8 (May 2017): 1055–64. http://dx.doi.org/10.1097/qad.0000000000001460.

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Chawla, K., A. Chawla, and P. Hegde. "Role of PCR for diagnosing male genital tuberculosis." International Journal of Infectious Diseases 45 (April 2016): 391. http://dx.doi.org/10.1016/j.ijid.2016.02.837.

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Rusia, Kaveri, Bhushan Madke, and Yash Kashikar. "Case Report: Concomitant presence of two STIs in a male patient." F1000Research 12 (June 20, 2023): 706. http://dx.doi.org/10.12688/f1000research.134667.1.

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Background: The spirochaete Treponema pallidum subsp. pallidum, which causes the infectious disease syphilis, can be spread through sexual contact or perinatal transmission. In recent years, cases of syphilis have increased, especially among individuals engaging in behaviour that makes them more vulnerable (condomless sex and multiple sexual partners) and in men who have sex with men. Condylomata acuminata (external genital warts) is one of the most common viral sexually transmitted infections (STIs). Individuals who are behaviourally vulnerable are also highly prone to be exposed to one or more STIs. Our case exemplifies the occurrence of two STIs in a young man who was behaviourally vulnerable to acquiring STIs. Case: We report a case of a 21-year-old year old heterosexual man presenting with concomitant primary syphilis and genital warts. He presented with a painless genital ulcer and warty growths on his glans penis. Examination showed a painless indurated ulcer and multiple genital warts. Serology was positive for quantitative serological disease research laboratory test (1:16 titre). The patient was diagnosed with two concomitant STIs. He was treated as per the latest Centers for Disease Control and Prevention (CDC) guidelines for primary syphilis and podophyllin resin for genital warts. After four weeks, the genital ulcer showed complete healing and there was a significant reduction of genital warts. Conclusions: Individuals with multiple sexual partners engaging in sexual activity without the use of prevention tools are at a greater chance of acquiring two or more STIs. To reduce concomitant transmission, preventive measures against genital ulcer diseases caused by human papilloma virus, syphilis, herpes, and chancroid, such as early identification and treatment, and condom distribution, must be strengthened as part of national STI prevention. Patients with two or more STIs should be followed regularly to assess the progress of infection and should be offered timely medical treatment.

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Rusia, Kaveri, Bhushan Madke, and Yash Kashikar. "Case Report: Concomitant presence of two STIs in a male patient." F1000Research 12 (June 12, 2024): 706. http://dx.doi.org/10.12688/f1000research.134667.2.

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Background The spirochaete Treponema pallidum subsp. pallidum, which causes the infectious disease syphilis, can be spread through sexual contact or perinatal transmission. In recent years, cases of syphilis have increased, especially among individuals engaging in behaviour that makes them more vulnerable (condomless sex and multiple sexual partners). Condylomata acuminata (external genital warts) is one of the most common viral sexually transmitted infections (STIs). Individuals who are behaviourally vulnerable are also highly prone to two or more STIs. Our case exemplifies the occurrence of two STIs in a young man who was behaviourally vulnerable to acquiring STIs. Case We report a case of a 21-year-old year old heterosexual man presenting with concomitant primary syphilis and genital warts. He presented with a painless genital ulcer and warty growths on his glans penis. Examination showed a painless indurated ulcer and multiple genital warts. Serology was positive for quantitative Venereal disease research laboratory test (1:16 titre). The patient was diagnosed with two concomitant STIs. He was treated as per the latest Centers for Disease Control and Prevention (CDC) guidelines for primary syphilis and podophyllin resin for genital warts. After four weeks, the genital ulcer showed complete healing and there was a significant reduction of genital warts. Conclusions Individuals with multiple sexual partners engaging in sexual activity without the use of prevention tools are at a greater chance of acquiring two or more STIs. To reduce concomitant transmission, preventive measures against genital ulcer diseases like syphilis, herpes, and chancroid, such as early identification and treatment, and condom distribution, must be strengthened as part of national STI prevention. Patients with two or more STIs should be followed regularly to assess the progress of infection and should be offered timely medical treatment.

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Wang, Qian-Qiu, David Mabey, Rosanna W. Peeling, Mei-Li Tan, Da-Ming Jian, Ping Yang, Ming-Ying Zhong, and Guang-Ju Wang. "Validation of syndromic algorithm for the management of genital ulcer diseases in China." International Journal of STD & AIDS 13, no. 7 (July 1, 2002): 469–74. http://dx.doi.org/10.1258/09564620260079626.

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Objectives 1. To determine the aetiologies of genital ulcers in China. 2. To evaluate a modified WHO syndromic management algorithm for genital ulcer disease (GUD). Methods: Patients with genital ulcers were enrolled at their first visit to STD clinics in the cities of Shanghai and Chengdu. They were managed according to a modified WHO algorithm for GUD, in which no treatment was given for chancroid. A multiplex polymerase chain reaction was used to detect Treponema pallidum, Herpes simplex and Haemophilus ducreyi. Dark field examination and serology (rapid plasma reagin and Treponema pallidum particle agglutination assay (TPPA) were also used to diagnose syphilis. Results: A total of 227 male and female patients were enrolled. Syphilis alone was diagnosed in 78 (35%), genital herpes alone in 43 (19%), and both infections were present in 28 (12%). No diagnosis was made in 76 (34%). No case of chancroid was identified. The sensitivity of the algorithm for syphilis and herpes was 88.7% and 69.0% respectively, the specificity 95.0% and 50.0%. 12/106 cases of syphilis were incorrectly classified as herpes (11%), and did not receive treatment. More than 97% of patients followed up responded clinically to treatment. Conclusion: Further validation and revision of the WHO flowchart for GUD are needed.

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Umenzekwe, Chukwudi Christian, Anastacia Okwudili Ojimba, Francis Chinedu Ugoeze, Uchechukwu Mkpuma, Tochukwu Praise Nnanna, Juliet Ijeoma Mmerem, Chibuzor Ifeanyi Okpala, et al. "Genital Mpox without Extra-Genital Lesions or Constitutional Symptoms in a Nigerian Male: A Case Report." European Journal of Clinical Medicine 4, no. 6 (December 28, 2023): 21–23. http://dx.doi.org/10.24018/clinicmed.2023.4.6.320.

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Human mpox is a re-emerging orthopox virus infection. We report a 36-year-old Nigerian male who presented with a one-week history of insidious onset ulcer at the base of the penis with no associated extra-genital rash or constitutional symptoms. He had unprotected heterosexual intercourse 14 days prior to the onset of the genital lesion, with a partner who had itchy vagina discharge. Physical examination revealed a solitary granulating ulcer measuring 3 cm by 2.5 cm with multiple satellite pustular lesions. No extra-genital lesion was observed. Polymerase chain reaction of the swab of lesions was positive for mpox. This was atypical mpox which should be considered by clinicians evaluating persons for sexually transmitted diseases.

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Ball, Erin E., Patricia A. Pesavento, Koen K. A. Van Rompay, M. Kevin Keel, Anil Singapuri, Jose P. Gomez-Vazquez, Dawn M. Dudley, et al. "Zika virus persistence in the male macaque reproductive tract." PLOS Neglected Tropical Diseases 16, no. 7 (July 5, 2022): e0010566. http://dx.doi.org/10.1371/journal.pntd.0010566.

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Zika virus (ZIKV) is unique among mosquito-borne flaviviruses in that it is also vertically and sexually transmitted by humans. The male reproductive tract is thought to be a ZIKV reservoir; however, the reported magnitude and duration of viral persistence in male genital tissues vary widely in humans and non-human primate models. ZIKV tissue and cellular tropism and potential effects on male fertility also remain unclear. The objective of this study was to resolve these questions by analyzing archived genital tissues from 51 ZIKV-inoculated male macaques and correlating data on plasma viral kinetics, tissue tropism, and ZIKV-induced pathological changes in the reproductive tract. We hypothesized that ZIKV would persist in the male macaque genital tract for longer than there was detectable viremia, where it would localize to germ and epithelial cells and associate with lesions. We detected ZIKV RNA and infectious virus in testis, epididymis, seminal vesicle, and prostate gland. In contrast to prepubertal males, sexually mature macaques were significantly more likely to harbor persistent ZIKV RNA or infectious virus somewhere in the genital tract, with detection as late as 60 days post-inoculation. ZIKV RNA localized primarily to testicular stem cells/sperm precursors and epithelial cells, including Sertoli cells, epididymal duct epithelium, and glandular epithelia of the seminal vesicle and prostate gland. ZIKV infection was associated with microscopic evidence of inflammation in the epididymis and prostate gland of sexually mature males, pathologies that were absent in uninfected controls, which could have significant effects on male fertility. The findings from this study increase our understanding of persistent ZIKV infection which can inform risk of sexual transmission during assisted reproductive therapies as well as potential impacts on male fertility.

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Möhrenschlager, M., and J. Ring. "Male genital oedema – allergy and angio-oedema in the differential diagnosis." Journal of the European Academy of Dermatology and Venereology 22, no. 3 (March 2008): 369–70. http://dx.doi.org/10.1111/j.1468-3083.2007.02319.x.

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ELSNER, PETER, and ALBERT A. HARTMANN. "Gardnerella vaginalis in the Male Upper Genital Tract." Sexually Transmitted Diseases 14, no. 2 (April 1987): 122–23. http://dx.doi.org/10.1097/00007435-198704000-00015.

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Kumar, Ajay, Jenny Pun, Deepika Neupane, Saujan Subedi, Asim Mohammad, and Brijesh Sathian. "Non-Veneral Genital Dermatoses: A Study from Western Nepal." Nepal Journal of Dermatology, Venereology & Leprology 18, no. 1 (October 8, 2020): 18–23. http://dx.doi.org/10.3126/njdvl.v18i1.30313.

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Introduction: The etiology of dermatoses involving genital areas could be venereal or on-venereal. These disorders are responsible for mental distress and guilt which can be minimized by appropriate diagnosis and information to the patients. Objectives: To assess the clinical pattern and prevalence of various non venereal genital dermatoses in a referral center. Materials and Methods: This was a hospital-based descriptive study involving patients with non-venereal diseases visiting outpatient clinics of Department of Dermatology. After informed consent, all the parameters were recorded in a proforma and analyzed. Results: Total of 70 patients with non-venereal genital dermatoses were included. Mean age of the patients was 33 years. Majority were male, married and had history of irregular use of contraceptives. Duration of symptoms ranged from one to 36 months with mean of four months. Total 19 types of non-venereal skin diseases were noted with major complaint of itching in genitalia in 22 (31.4%). Primary site of involvement/complaint was vulva in 19 (27.1%), scrotum in 17 (24.3%), groin in 18 (25.7%) and penile area in 14 (20.0%). The most common final dermatological diagnosis in majority was fungal infections and neurodermatitis in 12.9% each. Extramarital relationship was reported by 37 out of 70 patients (52.9%), while 31 patients correlated their symptoms with sexual exposure. Conclusions: Itching was the most common presenting complaint with infective etiology. The current study highlighted the relevance of addressing non-venereal genital dermatoses in order to avoid the general misconception that all genital lesions are sexually transmitted.

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Puerta, Benito, and Stephen Baines. "Surgical diseases of the genital tract in male dogs 2. Penis and prepuce." In Practice 34, no. 3 (March 2012): 128–35. http://dx.doi.org/10.1136/inp.e1102.

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Guner, Ekrem, Kamil Gokhan Seker, and Osman Ozdemir. "Understanding the genital diseases of Ancient Anatolia in the light of the inscribed male genital offerings presented to gods." Türk Üroloji Dergisi/Turkish Journal of Urology 45, no. 5 (September 9, 2019): 384–88. http://dx.doi.org/10.5152/tud.2019.47527.

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El-Reshaid, Kamel, and Hosameldin Tawfik Sallam. "Male genital allergy with penile oedema and severe aseptic urethritis, due to vulvovaginal candidiasis, simulating sexually transmitted infection." Journal of Drug Delivery and Therapeutics 11, no. 3 (May 15, 2021): 4–6. http://dx.doi.org/10.22270/jddt.v11i3.4699.

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Sexually transmitted diseases (STDs) are frequently encountered and more than 1 million are acquired daily. Genital allergy (GA), on the other hand, is another uncommon cause of sexually transmitted disorders that should be considered if no infection is identified or genital soreness persists or worsens with antimicrobial therapy. In this case report; we present a patient, with severe GA (type I hypersensitivity reaction) to vulvovaginal candidiasis in his sex partner. He was initially misdiagnosed as STD as he presented with severe penile and urethral oedema culminating in hematuria and bladder neck obstruction due to severe urethral oedema. Our systematic approach in diagnosis and hence treatment of the patient and his sex partner is outlined. Keywords: Candidiasis, genital allergy, penile oedema, STD, urethritis.

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Rosado, Catarina, Ângela Rita Fernandes, Acácio Gonçalves Rodrigues, and Carmen Lisboa. "Impact of Human Papillomavirus Vaccination on Male Disease: A Systematic Review." Vaccines 11, no. 6 (June 9, 2023): 1083. http://dx.doi.org/10.3390/vaccines11061083.

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Human papillomavirus (HPV)-related diseases are highly prevalent in men worldwide, comprising external anogenital condyloma, anal intraepithelial neoplasia (AIN), penile intraepithelial neoplasia (PIN), and anogenital and oropharyngeal cancers. There is exceptionally low vaccine coverage in the male population. Only 4% of men were fully vaccinated, worldwide, as of 2019. The aim of this review is to assess the impact of HPV vaccination on male disease. Three databases (MEDLINE, Web of Science, Scopus) and Clinical Trials.gov were searched. We included thirteen studies, eight randomized controlled trials (RCTs), and five cohorts, comprising a total of 14,239 participants. Regarding anal disease, seven studies reported HPV vaccine efficacy ranging from 91.1% to 93.1% against AIN1, and ranging from 89.6% to 91.7% against AIN2|3 and anal cancer. Five studies showed an efficacy against genital condyloma of 89.9% in HPV-naïve males, varying between 66.7% and 67.2% in intention-to-treat populations. Studies reporting no efficacy have included older participants. These results support vaccination of young men previously infected, beyond HPV-naïve males. The evidence quality was moderate to low for most outcomes, namely genital diseases. RCTs are needed to assess the efficacy of HPV vaccination on male oropharyngeal cancer.

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Diem, Kurt, David C. Nickle, Alexis Motoshige, Alan Fox, Susan Ross, James I. Mullins, Lawrence Corey, Robert W. Coombs, and John N. Krieger. "Male Genital Tract Compartmentalization of Human Immunodeficiency Virus Type 1 (HIV)." AIDS Research and Human Retroviruses 24, no. 4 (April 2008): 561–71. http://dx.doi.org/10.1089/aid.2007.0115.

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O'Farrell, Nigel, Maria Quigley, and Paul Fox. "Association between the intact foreskin and inferior standards of male genital hygiene behaviour: a cross-sectional study." International Journal of STD & AIDS 16, no. 8 (August 1, 2005): 556–59. http://dx.doi.org/10.1258/0956462054679151.

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This study was undertaken to determine whether non-circumcised men have inferior standards of genital hygiene behaviour, as measured by reported washing of the whole penis, compared with circumcised men. Male attenders at a sexually transmitted infections (STI) clinic at Ealing Hospital, London had routine STI tests and examinations performed and were asked about the frequency and thoroughness of genital washing. One hundred and fifty non-circumcised and 75 circumcised men were enrolled. Not always washing the whole penis, including retracting the foreskin in non-circumcised men every time they washed (defined as inferior genital hygiene behaviour) was more common in non-circumcised (26%) than circumcised men (4%) (crude odds ratio = 8.43, 95% confidence interval: 2.51–28.3, P<0.001) and those with balanitis (42% and 5%, P=0.036). Circumcised men were more likely than non-circumcised men to wash the genital area more than once a day (37% and 19%, P=0.011). Studies investigating the relationship between male circumcision status and other outcomes, for example HIV infection, should include assessment of genital hygiene.

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Paudel, Vikash, Deepa Chudal, Upama Paudel, and Dwarika Prasad Shrestha. "A clinical and epidemiological study of non-venereal genital dermatoses: A cross-sectional, hospital-based study from Nepal." Our Dermatology Online 13, no. 1 (January 3, 2022): 16–21. http://dx.doi.org/10.7241/ourd.20221.3.

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Background: Non-venereal genital dermatoses are the conditions of the genitalia that are not transmitted sexually. They may be confused with venereal diseases and be responsible for concerns among patients as well as diagnostic dilemmas for physicians. This study was conducted to determine the prevalence and describe the patterns of non-venereal genital conditions. Methods: This was a hospital-based, cross-sectional, prospective study conducted in a tertiary center in Kathmandu, Nepal, over a period of one year. Non-probability purposive sampling was employed to select the samples. Two hundred patients were enrolled in the study. Ethical approval was taken prior to the study. Detailed history taking along with a complete cutaneous examination were conducted for all patients and recorded in a preformed proforma. Results: Among 21366 patients, two hundred patients had non-venereal genital dermatoses. The prevalence of non-venereal dermatoses was 0.93 %. The mean age of the patient was 29.5 ± 15 years, ranging from 2 months to 81 years. The male-to-female ratio was 2.7:1. Itching was the most common presentation (46%). Fifty-four different types of non-venereal diseases were encountered and classified into inflammatory lesions (n = 84; 42%), infections and infestations (n = 43; 21.5%), normal variants and benign abnormalities (n = 41; 20.5%), and miscellaneous (n = 21; 10.5%). The most common were, among inflammatory dermatoses, drug reactions (11.5%) and eczema (6.5%) and, among infections and infestations, scabies (9.5%) and fungal infections (7.5%). Conclusion: Non-venereal genital dermatoses are important yet less common dermatological conditions. A number of patients have misconceptions about them as venereal. A comprehensive study of non-venereal dermatological genital conditions is required for careful management to minimize morbidity.

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XIN, H. N., H. J. LI, Z. LI, X. W. LI, M. F. LI, H. R. ZHANG, B. X. FENG, et al. "Genital HPV infection among heterosexual and homosexual male attendees of sexually transmitted diseases clinic in Beijing, China." Epidemiology and Infection 145, no. 13 (August 8, 2017): 2838–47. http://dx.doi.org/10.1017/s0950268817001698.

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SUMMARYHuman papillomavirus (HPV) has been identified as etiologic agent of various cancers for both men and women. However, HPV vaccine has not been recommended for men in China by far. To provide more evidences to promote HPV vaccination among males at high-risk of infection, this study investigated genital HPV genotypes among male attendees of sexually transmitted disease (STD) clinic. Male attendees (⩾18 years old) were recruited from STD clinic of Beijing Ditan Hospital. Data on sociodemographic characteristics and self-reported sexual behaviors were collected based on questionnaire. Genital swab specimens were collected for HPV genotypes. Finally, a total of 198 eligible participants were included in the study. Nearly half of them were infected with at least one type of HPV. The prevalence of genital infection among participants with only heterosexual behaviors (50·91%, 56/110) was significantly higher than those with only homosexual behaviors (36·36%, 32/88) (P < 0·001). However, the distribution pattern of the most frequently observed HPV subtypes were found to be similar between these two subgroups. HPV31, HPV18, HPV16 and HPV58 were the most frequently identified high-risk types and HPV11, HPV6, HPV81 and HPV61 were the most frequently observed low-risk types. Our results, although need further verification by larger sample size, suggested that currently available HPV vaccines covered most prevalent HPV types observed in Chinese men. As HPV vaccine has been approved for application in females in China, molecular epidemiological studies and intervention studies among high-risk males should be promoted as well.

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Kaya, Abdurrahman, and Sibel Yıldız Kaya. "A case of COVID-19–related acute genital ulceration in a male." International Journal of STD & AIDS 33, no. 6 (March 25, 2022): 622–24. http://dx.doi.org/10.1177/09564624221085726.

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COVID-19 is a viral infection which can present with various clinical manifestations. While it primarily affects the respiratory tract, several other manifestations including skin involvements have been reported. Dermatologic manifestations are uncommon, and its prevalence is not well-known. In COVID-19, there have been two reports of acute genital ulceration to date, and both are female. Here, we report a male patient with COVID-19 complicated by acute genital ulceration in the course of the illness.

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Puerta, Benito, and Stephen Baines. "Surgical diseases of the genital tract in male dogs 1. Scrotum, testes and epididymides." In Practice 34, no. 2 (February 2012): 58–65. http://dx.doi.org/10.1136/inp.e327.

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Noda, Angel A., Orestes Blanco, Consuelo Correa, Lissette Pérez, Vivian Kourí, and Islay Rodríguez. "Etiology of Genital Ulcer Disease in Male Patients Attending a Sexually Transmitted Diseases Clinic." Sexually Transmitted Diseases 43, no. 8 (August 2016): 494–97. http://dx.doi.org/10.1097/olq.0000000000000470.

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Xu, Xijin, Yuling Zhang, Taofeek Akangbe Yekeen, Yan Li, Bingrong Zhuang, and Xia Huo. "Increase male genital diseases morbidity linked to informal electronic waste recycling in Guiyu, China." Environmental Science and Pollution Research 21, no. 5 (November 24, 2013): 3540–45. http://dx.doi.org/10.1007/s11356-013-2289-2.

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Gorse, G. J., and R. B. Belshe. "Male Genital Tuberculosis: A Review of the Literature with Instructive Case Reports." Clinical Infectious Diseases 7, no. 4 (July 1, 1985): 511–24. http://dx.doi.org/10.1093/clinids/7.4.511.

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Vourvahis, Manoli, Hiba L. Tappouni, Kristine B. Patterson, Ya-Chi Chen, Naser L. Rezk, Susan A. Fiscus, Brian P. Kearney, et al. "The Pharmacokinetics and Viral Activity of Tenofovir in the Male Genital Tract." JAIDS Journal of Acquired Immune Deficiency Syndromes 47, no. 3 (March 2008): 329–33. http://dx.doi.org/10.1097/qai.0b013e3181632cc3.

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Portugal, Isabella Batista Martins, Fernando Adami, Jean Henri Schoueri, Leandro Fórnias Machado Rezende, Fernando Luiz Affonso Fonseca, Gerson Ferrari, Luiz Carlos de Abreu, and Luis Eduardo Werneck De Carvalho. "Reduction in prostate cancer hospitalizations in the COVID-19 pandemic epicenter of Latin America." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e18814-e18814. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e18814.

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e18814 Background: The novel SARS-CoV-2 coronavirus disease 2019 (COVID-19) has disrupted health care systems worldwide since December 2019 causing atypical pneumonia and affecting multiple body organs. In Latin America, COVID-19 had its first case in the megacity of São Paulo, Brazil, thus being the starting point and epicenter of this disease. In this context, prostate cancer (PC) is the most common non-skin cancer among men and its preventive healthcare is substantial to public health surveillance. Additionally, PC raises particular interest during COVID-19 outbreak as PC androgen-deprivation therapies have shown to mitigate SARS-CoV-2 infection, which suggests an association between SARS-CoV-2 and PC cells. Thus, the consequences of the COVID-19 outbreak on male genital cancers care remain inconclusive and will probably be felt for decades. This study aimed to determine the impact of pandemic on the incidence of hospital admissions (HA) due to malignant neoplasms of male genital organs in the city of São Paulo, Brazil. Methods: This is a cross-sectional study of the HAs due to malignant neoplasms of male genital organs in the city of São Paulo comparing the outbreak period (January-June 2020) and a pre-pandemic corresponding period of the years 2017-2019. Data were obtained from the Brazilian Unified Health System - Hospital Information System database according to the chapter II of the International Classification of Diseases - 10th revision (ICD-10). Linear regression was used to analyze the relationship between the incidence of HAs and time (months). Results: A significant reduction in HAs due to malignant neoplasms of male genital organs was observed in PC, but not other malignant neoplasms of male genital organs during the outbreak period (January-June 2020). PC (-19, CI -36 to -1) showed to be remarkably affected while other male genital cancers (-1, CI -5 to 3) did not (Table). Conclusions: Our findings seem to be associated to delayed oncological care delivery to PC during the lockdown and health system disruption. Further studies are required to evaluate the impact of the ongoing pandemic in malignant neoplasm of male genital organs, particularly PC, in order to strategically corroborate public health actions for implications of COVID-19 pandemic. Linear regression of hospital admissions for the years 2017-2020 (January until June) due to malignant neoplasms of male genital organs (chapter II of the ICD-10). Municipality of São Paulo, São Paulo, Brazil.[Table: see text]

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Kayuni, S. A., P. L. A. M. Corstjens, E. J. LaCourse, K. E. Bartlett, J. Fawcett, A. Shaw, P. Makaula, et al. "How can schistosome circulating antigen assays be best applied for diagnosing male genital schistosomiasis (MGS): an appraisal using exemplar MGS cases from a longitudinal cohort study among fishermen on the south shoreline of Lake Malawi." Parasitology 146, no. 14 (August 27, 2019): 1785–95. http://dx.doi.org/10.1017/s0031182019000969.

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AbstractWe provide an update on diagnostic methods for the detection of urogenital schistosomiasis (UGS) in men and highlight that satisfactory urine-antigen diagnostics for UGS lag much behind that for intestinal schistosomiasis, where application of a urine-based point-of-care strip assay, the circulating cathodic antigen (CCA) test, is now advocated. Making specific reference to male genital schistosomiasis (MGS), we place greater emphasis on parasitological detection methods and clinical assessment of internal genitalia with ultrasonography. Unlike the advances made in defining a clinical standard protocol for female genital schistosomiasis, MGS remains inadequately defined. Whilst urine filtration with microscopic examination for ova of Schistosoma haematobium is a convenient but error-prone proxy of MGS, we describe a novel low-cost sampling and direct visualization method for the enumeration of ova in semen. Using exemplar clinical cases of MGS from our longitudinal cohort study among fishermen along the shoreline of Lake Malawi, the portfolio of diagnostic needs is appraised including: the use of symptomatology questionnaires, urine analysis (egg count and CCA measurement), semen analysis (egg count, circulating anodic antigen measurement and real-time polymerase chain reaction analysis) alongside clinical assessment with portable ultrasonography.

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Jantos, C. A., J. Augustin, B. Durchfeld-Meyer, W. Baumgärtner, and H. G. Schiefer. "Experimental genital tract infection withChlamydia psittaci (GPIC agent) in male rats." Infection 26, no. 2 (March 1998): 126–30. http://dx.doi.org/10.1007/bf02767776.

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Rowen, D. "Streptococci and the Genital Tract." International Journal of STD & AIDS 4, no. 2 (March 1993): 63–66. http://dx.doi.org/10.1177/095646249300400201.

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Streptococci of Lancefield Group B (GBS) are known to cause maternal sepsis and neonatal infection, whereas streptococci Lancefield Group A (GAS) cause vulvo-vaginitis in both children and adults. Prevalence of SGB colonization of the lower genital tract of normal women is between 4–18%, with higher rates found in hospital personnel and delivery rooms. Such high carriage rates may be a significant factor in nosocomial transmission of GBS to neonates. Symptomatic infection is uncommon and usually secondary to other pathological states. Amnionitis is a complication of vaginal carriage of GBS and there is now evidence that chorioamnionitis is associated with pre-term labour and its attendant problems. GBS infection of the male genitalia has also been described. Intrapartum chemoprophylaxis has been shown to prevent early onset GBS disease of the neonate. Prevalence of GAS in the genital tract is lower than that for GBS, but is more likely to be symptomatic. The response to penicillin is usually prompt. Optimal drug regimens need to be determined, particularly for use in pregnancy.

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Journal articles on the topic 'Male genital diseases'

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