Academic literature on the topic 'Malignancy; Nervous system'

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Journal articles on the topic "Malignancy; Nervous system"

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Youle, Richard J. "Immunotoxins for central nervous system malignancy." Seminars in Cancer Biology 7, no. 2 (1996): 65–70. http://dx.doi.org/10.1006/scbi.1996.0010.

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Lister, Andrew, Lauren E. Abrey, and John T. Sandlund. "Central Nervous System Lymphoma." Hematology 2002, no. 1 (2002): 283–96. http://dx.doi.org/10.1182/asheducation-2002.1.283.

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Abstract Central nervous system involvement with malignant lymphoma whether primary or secondary is an uncommon but not rare complication observed in the management of patients with hematological malignancy. Its importance lies in the considerable morbidity and mortality with which it is associated and the inadequacy of therapy. In Section I, Dr. Lauren Abrey addresses the totality of the problem of primary central nervous system lymphoma, with emphasis on strategies increasingly dependent on systemic chemotherapy. In Section II, Dr. John Sandlund reviews the success of sequential clinical tri
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Kaufman, Stuart S., Constance M. Goldgar, Francis Fitzmaurice, Dean L. Antonson, and Jon A. Vanderhoof. "Intestinal Abnormalities with Central Nervous System Malignancy." Journal of Pediatric Gastroenterology and Nutrition 5, no. 4 (1986): 665–70. http://dx.doi.org/10.1097/00005176-198607000-00027.

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Hall, Walter A., and Øystein Fodstad. "Immunotoxins and central nervous system neoplasia." Journal of Neurosurgery 76, no. 1 (1992): 1–12. http://dx.doi.org/10.3171/jns.1992.76.1.0001.

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✓ The poor prognosis associated with central nervous system (CNS) malignancy has led investigators to seek new, innovative treatment modalities. Immunotoxins, carrier molecules linked to toxic agents, combine high specificity for tumor-associated antigens with extreme potency. The rationale for both the development of these compounds and for their application to CNS neoplasia is explained. This report discusses the design and construction of immunoconjugates, using toxins that differ in their mechanism of action bound to ligands directed against various antigens. A comparison is made between t
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Kurtzman, Drew J. B., Andrew J. Fabiano, Jingxin Qiu, and Nathalie C. Zeitouni. "Muir–Torre Syndrome and Central Nervous System Malignancy." Dermatologic Surgery 41, no. 7 (2015): 856–59. http://dx.doi.org/10.1097/dss.0000000000000376.

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Galli, Jonathan, and John Greenlee. "Paraneoplastic Diseases of the Central Nervous System." F1000Research 9 (March 6, 2020): 167. http://dx.doi.org/10.12688/f1000research.21309.1.

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Paraneoplastic neurological syndromes are nonmetastatic complications of malignancy secondary to immune-mediated neuronal dysfunction or death. Pathogenesis may occur from cell surface binding of antineuronal antibodies leading to dysfunction of the target protein, or from antibodies binding against intracellular antigens which ultimately leads to cell death. There are several classical neurological paraneoplastic phenotypes including subacute cerebellar degeneration, limbic encephalitis, encephalomyelitis, and dorsal sensory neuropathy. The patient’s clinical presentations may be suggestive t
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Deangelis, Lisa M. "Primary central nervous system lymphoma as a secondary malignancy." Cancer 67, no. 5 (1991): 1431–35. http://dx.doi.org/10.1002/1097-0142(19910301)67:5<1431::aid-cncr2820670527>3.0.co;2-k.

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Schiff, David. "Quantifying the burden of primary central nervous system malignancy." Neuro-Oncology 18, no. 1 (2015): 5–6. http://dx.doi.org/10.1093/neuonc/nov287.

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Huber, Katrin, Isabelle Janoueix-Lerosey, Wolfgang Kummer, Hermann Rohrer, and Arthur S. Tischler. "The sympathetic nervous system: malignancy, disease, and novel functions." Cell and Tissue Research 372, no. 2 (2018): 163–70. http://dx.doi.org/10.1007/s00441-018-2831-0.

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Saddawi-Konefka, Robert, and John R. Crawford. "Chronic Viral Infection and Primary Central Nervous System Malignancy." Journal of Neuroimmune Pharmacology 5, no. 3 (2010): 387–403. http://dx.doi.org/10.1007/s11481-010-9204-0.

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Dissertations / Theses on the topic "Malignancy; Nervous system"

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Thompson, Samantha Lee. "A genetic basis for the development of prognostic indication in childhood primitive neuroectodermal tumours." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324697.

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Cousins, Antony Francis. "Investigation into survival mechanisms of malignant B cells in the central nervous system." Thesis, University of Glasgow, 2019. http://theses.gla.ac.uk/39009/.

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Introduction: Acute lymphoblastic leukaemia (ALL) is the commonest childhood cancer. In the early trials of ALL treatment, central nervous system (CNS) relapse was a common occurrence - the introduction of CNS-directed therapy in the 1970s was associated with the largest single improvement in outcome for childhood ALL. Today, despite universal intensive CNS-directed therapy - with significant associated toxicity - the CNS is involved in around 50% of ALL relapses, with approximately 50% of these being isolated CNS (iCNS) relapse. Whilst many factors increase risk of CNS relapse, few are specif
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Clark, Aaron J. "The Expression and Function of Wilms' Tumor 1 in Malignant Glioma." VCU Scholars Compass, 2006. http://hdl.handle.net/10156/1665.

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Books on the topic "Malignancy; Nervous system"

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Papanastassiou, Varnavas. Applications of radiolabelled monoclonal antibodies in the management of malignant disease of the central nervous system. University of Manchester, 1994.

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NATO Advanced Research Workshop on Regulation of Extravascular Fibrinolysis in Nervous System Development and Disease (1989 Maratea, Italy). Serine proteases and their serpin inhibitors in the nervous system: Regulation in development and in degenerative and malignant disease. Edited by Festoff Barry W, Hantaï Daniel, and North Atlantic Treaty Organization. Scientific Affairs Division. Plenum Press, 1990.

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Jordan, Nerissa. Non-metastatic neurological manifestations of malignancy. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0238.

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Neurological complications of systemic malignancy are frequent. They may reflect direct local effects of the tumour; CNS infection; side effects of chemotherapy or radiotherapy; nutritional or metabolic derangements; or a paraneoplastic syndrome. The paraneoplastic neurological syndromes are a group of disorders associated with a malignancy outside the nervous system. The pathophysiology is immune-mediated, with the tumour’s expression of neuronal proteins invoking antibody formation, which in turn results in neurological symptoms. This chapter will mainly focus on these syndromes.
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Jellinger, K., and F. Seitelberger. Malignant Lymphomas of the Nervous System: International Symposium. Springer, 2014.

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Schoenberg, Bruce S. Multiple Primary Malignant Neoplasms: The Connecticut Experience, 1935-1964. Springer Berlin Heidelberg, 2011.

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Hain, Richard D. W., and Satbir Singh Jassal. Malignant diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198745457.003.0016.

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With respect to palliative medicine, malignant diseases can be considered in three broad groups: haemopoietic malignancies, central nervous system tumours, and other solid tumours. The likelihood of needing referral for specialist palliative medicine is influenced by prognosis, as well as by incidence, and therefore change as outcomes improve. This chapter includes an easy-to-assimilate list of the commonest symptoms experienced by children with cancer, broken down by incidence. A detailed examination of the interface between oncology and palliative care is provided, with discussion of the pri
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Watts, Richard A., and Eleana Ntatsaki. Miscellaneous vasculitides. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0137.

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The vasculitides are a group of relatively rare conditions with a broad spectrum of clinical presentations that can cause significant morbidity and mortality. Classification of the vasculitic syndromes is done according to the size of the vessels affected and also the presence of anti-neutrophil cytoplasmic antibodies (ANCA). Vasculitides can be either primary or secondary to an underlying systemic disease, malignancy, or infection. This chapter covers the spectrum of the secondary vasculitides; some of the non-ANCA-associated primary vasculitides and miscellaneous types of vasculitic syndrome
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Oliver, Nora, and Elizabeth Chiao. Malignant Diseases in HIV. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190493097.003.0033.

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Malignancies were one of the earliest recognized manifestations that led to the eventual description of the AIDS epidemic. Kaposi’s sarcoma was one of the first entities described in association with AIDS. Subsequently, intermediate-grade and high-grade non-Hodgkin’s lymphoma, invasive cervical cancer, and primary central nervous system lymphoma were defined by the Centers for Disease Control and Prevention as “AIDS-defining conditions.” Since the advent of combination antiretroviral therapy, several other cancers that are not AIDS-defining have been found to have an increased incidence in pat
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Bowker, Lesley K., James D. Price, Ku Shah, and Sarah C. Smith. Neurology. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198738381.003.0007.

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This chapter provides information on the ageing brain and nervous system, tremor, neuropathic pain/neuralgia, presentation of Parkinson’s disease, management of Parkinson’s disease, diseases masquerading as Parkinson’s disease, epilepsy and its drug treatment, neuroleptic malignant syndrome, motor neuron disease, peripheral neuropathies, subdural haematoma, sleep and insomnia, and other sleep disorders.
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Kleihues, Paul, Elisabeth Rushing, and Hiroko Ohgaki. The 2016 revision of the WHO classification of tumours of the central nervous system. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199651870.003.0001.

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The revised fourth edition of the WHO classification of Tumours of the Central Nervous System, published in 2016, comprises several newly recognized tumour entities, and a significant restructuring of the classification, mainly based on genetic profiling. Glioblastomas are now classified into two major types. Isocitrate dehydrogenase (IDH)-wildtype glioblastoma (primary glioblastoma IDH-wildtype) develops rapidly de novo without a recognizable precursor lesion. IDH-mutant glioblastoma (secondary glioblastoma IDH-mutant) develops more slowly through malignant progression from diffuse or anaplas
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Book chapters on the topic "Malignancy; Nervous system"

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Cho, Steve Y., and Howard A. Fine. "Central Nervous System Malignancy and Clinical Pharmacology." In Handbook of Anticancer Pharmacokinetics and Pharmacodynamics. Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-734-5_23.

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Abraham, Peter, and Jason Handwerker. "Therapy Response Imaging in Central Nervous System (CNS) Malignancy." In Therapy Response Imaging in Oncology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-31171-1_4.

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Moll, Annette C., Tamara Marees, Machteld I. Bosscha, and Flora E. van Leeuwen. "Long-Term Survivors of Retinoblastoma: Risk of Increased Second Malignancy." In Tumors of the Central Nervous System, Volume 8. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-4213-0_15.

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Poplack, David G., and Riccardo Riccardi. "Pharmacologic approaches to the treatment of central nervous system malignancy." In The Role of Pharmacology in Pediatric Oncology. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-4267-7_9.

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Gallo, R. C. "Human Lymphotropic Viruses (T and B Cell) and their Role in Malignancy, AIDS and Central Nervous System Disease." In Verhandlungen der Deutschen Gesellschaft für Innere Medizin. J.F. Bergmann-Verlag, 1987. http://dx.doi.org/10.1007/978-3-642-85460-6_109.

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Garman, Robert H. "Malignant Reticulosis, Rat." In Nervous System. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-83516-2_21.

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Luccarelli, G., M. E. Ferioli, G. Broggi, and G. Scalabrino. "Levels of Polyamine Biosynthetic Decarboxylase Activities as Indicators of the Degree of Malignancy of Human Primary Central Nervous System Tumors." In Brain Oncology Biology, diagnosis and therapy. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3347-7_23.

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Mitsumori, Kunitoshi, Steven A. Stefanski, and Robert R. Maronpot. "Benign and Malignant Neoplasms, Meninges, Rat." In Nervous System. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-83516-2_20.

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Sutton, M. L. "Adult Central Nervous System." In The Radiotherapy of Malignant Disease. Springer London, 1991. http://dx.doi.org/10.1007/978-1-4471-3168-7_8.

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Sutton, M. L. "Adult Central Nervous System." In The Radiotherapy of Malignant Disease. Springer London, 1985. http://dx.doi.org/10.1007/978-1-4471-3322-3_8.

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Conference papers on the topic "Malignancy; Nervous system"

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Ollila, Thomas A., Habibe Kurt, Jozal Waroich, et al. "Abstract PO-38: Genomic subtypes correlate with the risk of central nervous system (CNS) recurrence in diffuse large B-cell lymphoma (DLBCL)." In Abstracts: AACR Virtual Meeting: Advances in Malignant Lymphoma; August 17-19, 2020. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2643-3249.lymphoma20-po-38.

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Hood, R. Lyle, Tobias Ecker, John Rossmeisl, John Robertson, and Christopher G. Rylander. "Improving Convection-Enhanced Delivery Through Photothermal Augmentation of Fluid Dispersal." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80720.

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Malignant tumors of the central nervous system are the third leading cause of cancer-related deaths in adolescents and adults between the ages of 15 and 34; in children, brain tumors are the leading cause of cancer death. Convection-enhanced delivery (CED) has emerged as a promising method for the transport of high concentrations of chemotherapeutic macromolecules to brain tumors. CED is a minimally-invasive surgical procedure wherein a stereotactically-guided small-caliber catheter is inserted into the brain parenchyma, to a tumor site, for low flowrate infusion of chemotherapy [1]. This dire
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Khatua, Soumen, Vidya Gopalakrishnan, Laurence Cooper, et al. "Abstract CT033: Phase I study of intraventricular infusions of autologous exvivo expanded NK cells in children with recurrent/refractory malignant posterior fossa tumors of the central nervous system." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-ct033.

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Khatua, Soumen, Dean Lee, Laurence Cooper, et al. "Abstract CT216: Phase I study of intraventricular infusions of autologous ex vivo expanded NK cells in children with recurrent/refractory malignant posterior fossa tumors of the central nervous system." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-ct216.

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Khatua, Soumen, Dean Lee, Laurence Cooper, et al. "Abstract CT216: Phase I study of intraventricular infusions of autologous ex vivo expanded NK cells in children with recurrent/refractory malignant posterior fossa tumors of the central nervous system." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-ct216.

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