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Journal articles on the topic 'Malignant ascites'

Author: Grafiati

Published: 5 June 2025

Last updated: 16 July 2025

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1

Sastry, Anand Sankar, Subash Ch Mahapatra, and Vidyasagar Dumpula. "Ascitic fluid analysis with special reference to serum ascites cholesterol gradient and serum ascites albumin gradient." International Journal of Research in Medical Sciences 5, no. 2 (2017): 429. http://dx.doi.org/10.18203/2320-6012.ijrms20170059.

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Background: Ascites being a common clinical problem with a vast spectrum of etiologies, less expensive and widely available biochemical parameters are required to differentiate ascites which can correlate with pathogenesis and pin point towards an etiology with high sensitivity and significant accuracy. Aims of the study were to determine the sensitivity, specificity and diagnostic efficacy of serum ascites albumin Gradient (SAAG) and that of ascitic fluid total protein (AFTP), evaluating their diagnostic role in identifying the etiology of ascites, to determine the diagnostic efficacy of Asci

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2

Prabhu, Mukhyaprana, Rahul Sai Gangula, and Weena Stanley. "Diagnostic Utility of Serum Ascites Lipid and Protein Gradients in Differentiation of Ascites." International Journal of Hepatology 2019 (June 2, 2019): 1–10. http://dx.doi.org/10.1155/2019/8546010.

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Context. Ability of SAAG to differentiate malignant ascites from other aetiologies like tubercular peritonitis is a major problem. Alternate screening test is needed for differentiating ascites due to malignancy from those due to tubercular peritonitis. Aims. To study the diagnostic utility of serum ascites lipid gradients and serum ascites protein gradients in pathophysiological differentiation of ascites. Settings and Design. The present study is a prospective, descriptive, hospital-based, cross-sectional study. Methods and Material. The study was conducted on patients with ascites who were

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Mayank, B. P. Priyadarshi, Mahendra Singh, Ashok Kumar Verma, and Tanu Midha. "Study the usefulness of ascitic fluid cholesterol level in diagnosis of malignant related ascites." International Journal of Advances in Medicine 5, no. 2 (2018): 400. http://dx.doi.org/10.18203/2349-3933.ijam20181077.

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Background: The differential diagnosis of ascites is a common clinical problem. However, the capability to distinguish malignant from non-malignant causes of ascites using available biochemical techniques would obviate many expensive and time-consuming diagnostic studies on patients presenting with ascites of unknown etiology. Therefore, this study was planned to evaluate usefulness of ascitic fluid cholesterol level in diagnosis of malignant ascites.Methods: Author conducted an observational study in 80 patients, those admitted and willing to give consent in the department of Medicine, LLR an

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4

Yun, Jina, Ju-Sun Song, Jeong-Ju Yoo, et al. "Microbial and Immune Landscape of Malignant Ascites: Insights from Gut, Bladder, and Ascitic Fluid Analyses." Cancers 17, no. 8 (2025): 1280. https://doi.org/10.3390/cancers17081280.

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Background/Objectives: Malignant ascites frequently arises in advanced cancers with peritoneal metastasis and is associated with poor outcomes. Known mechanisms include lymphatic obstruction by tumor cells, increased vascular permeability, and sodium retention via the renin–angiotensin–aldosterone system; however, the pathogenesis remains not fully understood. We investigated whether gut and bladder microbiomes correlate with malignant ascites development or progression and whether the immune microenvironment in ascitic fluid is altered. Methods: We enrolled 66 histologically confirmed cancer

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Sun, Juan, Yan-Xiang Chang, and Chun-Yan Niu. "Evaluation of ascitic soluble human leukocyte antigen-G for distinguishing malignant ascites from benign ascites." Tumor Biology 39, no. 11 (2017): 101042831772684. http://dx.doi.org/10.1177/1010428317726840.

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The overexpression of soluble human leukocyte antigen-G is associated with malignant tumours. The purpose of our study was to detect soluble human leukocyte antigen-G concentrations in ascites and to evaluate the value of ascitic soluble human leukocyte antigen-G for the diagnosis of malignant ascites. Enzyme-linked immunosorbent assay was used to detect soluble human leukocyte antigen-G levels in 64 patients with malignant ascites and 30 patients with benign ascites. Receiver operating characteristic curves were used to evaluate the diagnostic efficacy of ascitic soluble human leukocyte antig

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6

Sulya, Maneesh, Ashish Kosthi, U. R. Singh, and Reeni Malik. "Diagnostic Significance of Serum Ascites cholesterol to Differentiate Malignant and non Malignant Ascites." Annals of Pathology and Laboratory Medicine 4, no. 5 (2017): A482—A486. http://dx.doi.org/10.21276/apalm.1371.

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7

Rasheed, Bilal, Muhammad Imran, Rabia Parveen, et al. "Diagnostic Value of Ascitic Fluid Cholesterol Level in Differentiating Malignant Ascites from Non-Malignant Ascites." Journal of Health and Rehabilitation Research 3, no. 2 (2023): 687–91. http://dx.doi.org/10.61919/jhrr.v3i2.209.

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Background: Ascites, the accumulation of fluid in the peritoneal cavity, poses significant diagnostic challenges, particularly in differentiating between malignancy-related ascites (MRA) and non-malignant ascites (NMA). This differentiation is critical for appropriate clinical management. Objective: The study aimed to evaluate the diagnostic value of ascitic fluid cholesterol levels in distinguishing MRA from NMA. Methods: This cross-sectional study enrolled 48 patients with ascites, divided equally into Group A (MRA) and Group B (NMA). Diagnostic paracentesis was performed, and 20 ml of ascit

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8

Dede, Hysni, Rovena Roshi, Rovena Bode, Enver Roshi, and Jovan Basho. "The Role of Serum Ascites Albumin Gradient in the Differential Diagnosis of Ascites." Albanian Journal of Trauma and Emergency Surgery 6, no. 1 (2022): 933–38. http://dx.doi.org/10.32391/ajtes.v6i1.268.

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Introduction: Ascites is of Greek derivation (“askos”) and refers to a bag or sack. The word is a noun and describes pathologic fluid accumulation within the peritoneal cavity. Orientation in finding or excluding portal hypertension through examination of ascitic fluid is the first step towards an accurate diagnosis. Material and Methods: The aim of this study was to evaluate the role of SAAG (Serum Ascites Albumin Gradient) in the differential diagnosis between cirrhotic and malignant ascites. The SAAG is obtained by subtracting the value of serum albumin, the value of ascites albumin (

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9

Mui, Jasmine J., and David Morris. "Albendazole in malignant ascites: a case report and literature review on the successes and adverse effects of therapy." International Surgery Journal 8, no. 10 (2021): 3146. http://dx.doi.org/10.18203/2349-2902.isj20214012.

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Malignant ascites places a significant burden on the healthcare system and has a profound effect on patient quality of life. Albendazole (ABZ) is an anti-helminthic agent that has shown to rapidly reduce malignant ascites with minimal side effects in pre-clinical trials. The following case study explores the effect of ABZ on ascitic volume in a patient with malignant ascites secondary to metastatic colorectal adenocarcinoma. The patient is a 54-year-old man who underwent an ultrasound guided ascitic drainage for worsening ascites secondary to hepatic metastases from sigmoid adenocarcinoma. He

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10

Obahiagbon I and Ugiagbe RA. "An appraisal of ascitic fluid cytopathology in a Nigerian tertiary care setting." Ibom Medical Journal 14, no. 1 (2021): 10–15. http://dx.doi.org/10.61386/imj.v14i1.82.

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Background: The pathological accumulation of excess fluid in the peritoneal cavity is termed ascites. It is important to include cytological examination in the overall evaluation of ascitic fluid, so as to help make a distinction between malignant and non-malignant ascites in the management of patients.Aims and objectives: To appraise the practice of ascitic fluid cytopathology in the University of Benin Teaching Hospital (UBTH), Benin City.Materials and methods: Ascitic fluid specimens received at the department of Anatomical Pathology, UBTH, over a 5-year period (2015-2019), were examined ma

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11

Zhang, Jinyan, Rong Liang, Jiazhang Wei, et al. "Identification of Candidate Biomarkers in Malignant Ascites from Patients with Hepatocellular Carcinoma by iTRAQ-Based Quantitative Proteomic Analysis." BioMed Research International 2018 (September 23, 2018): 1–11. http://dx.doi.org/10.1155/2018/5484976.

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Almost all the patients with hepatocellular carcinoma (HCC) at advanced stage experience pathological changes of chronic liver cirrhosis, which generally leads to moderate ascites. Recognition of novel biomarkers in malignant ascites could be favorable for establishing a diagnosis for the HCC patients with ascites, and even predicting prognosis, such as risk of distant metastasis. To distinguish the proteomic profiles of malignant ascites in HCC patients from those with nonmalignant liver cirrhosis, an iTRAQ pipeline was built up to analyze the differentially distributed proteins in the malign

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12

Ebinama, Ugochi, Nathaniel R. Wilson, Anindita Ghosh, and Binsah S. George. "Therapeutic Management of Chronic Lymphocytic Leukemia Presenting with Recurrent Massive Ascites." Current Oncology 29, no. 10 (2022): 6787–93. http://dx.doi.org/10.3390/curroncol29100534.

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Chronic lymphocytic leukemia (CLL) is a lymphoproliferative malignancy that is categorized by the production and accumulation of CD5+ monoclonal B cell lymphocytes, commonly in the spleen, bone marrow, and peripheral blood; these are morphologically mature lymphocytes with abnormal immune function. Ascites, although common in solid organ malignancies such as ovarian, breast, and gastrointestinal, is a rare clinical manifestation in hematological malignancies. The case presented herein describes an elderly male patient with CLL who presented with transudative ascites 7 years after the completio

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13

Chandran, Dr Rabindran, and Dr D. Sharad Gedam. "Malignant Ascites." International Journal of Medical Research and Review 4, no. 7 (2016): 1086–87. http://dx.doi.org/10.17511/ijmrr.2016.i07.01.

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14

Elsakka, Ahmed, and Hooman Yarmohammadi. "Malignant Ascites." Digestive Disease Interventions 04, no. 03 (2020): 334–42. http://dx.doi.org/10.1055/s-0040-1717086.

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AbstractMalignant ascites negatively impacts patient's quality of life and has significant impact on the health care resources. Majority of management guidelines are based on systemic reviews that have predominately relied on retrospective data. Therefore, there is lack of high-level evidence-based studies. In this review, the etiologies, pathophysiology, and various treatment methods including diuretic therapy, large volume paracentesis, indwelling catheter placement, peritoneovenous shunt, transjugular intrahepatic portosystemic shunt, and other available novel and/or experimental options ar

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15

Enck, Robert E. "Malignant ascites." American Journal of Hospice and Palliative Medicine® 19, no. 1 (2002): 7–8. http://dx.doi.org/10.1177/104990910201900101.

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16

GARRISON, R. NEAL, LAWRENCE D. KAELIN, LOUIS S. HEUSER, and REBECCA H. GALLOWAY. "Malignant Ascites." Annals of Surgery 203, no. 6 (1986): 644–51. http://dx.doi.org/10.1097/00000658-198606000-00009.

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17

Mels, Guido Colloredo, Giorgio Bellati, Gioacchino Leandro, et al. "Malignant ascites." European Journal of Gastroenterology & Hepatology 5, no. 4 (1993): 251–56. http://dx.doi.org/10.1097/00042737-199304000-00010.

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18

Eitan, Ram, Oded Raban, Daliah Tsoref, et al. "Malignant Ascites." International Journal of Gynecological Cancer 28, no. 6 (2018): 1162–66. http://dx.doi.org/10.1097/igc.0000000000001276.

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19

Lyckholm, Laurie. "Malignant Ascites." Rehabilitation Oncology 15, no. 1 (1997): 19. http://dx.doi.org/10.1097/01893697-199715010-00023.

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20

Parsons, S. L., S. A. Watson, and R. J. C. Steele. "Malignant ascites." British Journal of Surgery 83, no. 1 (1996): 6–14. http://dx.doi.org/10.1002/bjs.1800830104.

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21

Aslam, Naeem, and Christopher R. Marino. "Malignant Ascites." Archives of Internal Medicine 161, no. 22 (2001): 2733. http://dx.doi.org/10.1001/archinte.161.22.2733.

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22

Khan, Mohammed Masudul Hassan, Farzana Rahman, Mohammad Mostafa Kamal, Farah Momtaz, Md Ismail Patwary, and Md Khairul Islam. "Role of Serum Ascites Albumin Gradient In The Etiologic Diagnosis of Ascites." Journal of Dhaka Medical College 31, no. 1 (2023): 120–24. http://dx.doi.org/10.3329/jdmc.v31i1.65486.

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Background: Classification based on ascitic fluid protein has been challenged on several occasions in diverse clinical situations, including cirrhotic patients on extended diuretic treatment, cardiac ascites, 1/3 individuals with malignant ascites, spontaneous bacterial peritonitis, and even normal ascitic fluid. Objective: The study’s objective was to observe the role of serum ascites albumin gradient (SAAG) in diagnosing Ascites. Methods: This cross-sectional observational study was conducted at the Department of Medicine, Sylhet M.A.G. Osmani Medical College Hospital, Bangladesh. with a tot

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Oguntoye, Oluwatosin O., Oluwafunmilayo A. Oguntoye, Olawale M. Adeniyi, Oluwadamilola Gideon Osasona, and Precious E. Nkereuwem. "Evaluation of Ascitic Fluid Cytology in a Tertiary Hospital in South-Western Nigeria: A 7-year Retrospective Study." Medical Journal of Dr. D.Y. Patil Vidyapeeth 17, no. 6 (2024): 1182–90. http://dx.doi.org/10.4103/mjdrdypu.mjdrdypu_937_23.

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Background: Ascites is the pathological accumulation of fluid within the peritoneal cavity of varied etiology. Various abnormalities can be detected through cytological analysis of ascitic fluid. Ascitic fluid cytology (AFC) is a rapid and cost-effective means of evaluating ascites to establish its nature and cause. Aim: To evaluate ascitic fluid cytological findings over a seven-year period and to correlate the cytological features with the clinical profile of the patients. Materials and Methods: This was an observational retrospective study conducted in a healthcare facility in south-western

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Amado, L. Valiña, M. A. Martínez Ortega, A. Ballesteros Vizoso, P. Argente Del Castillo, and M. M. Parera Roselló. "Malignancy-related ascites: Malignant peritoneal mesothelioma." Clinica Chimica Acta 493 (June 2019): S149—S150. http://dx.doi.org/10.1016/j.cca.2019.03.315.

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25

Venkateswaran, Aparajit Ram, Safa F. Elzein, Emilio D. Sulpizio, Bernard Chang, and Michael P. Kosty. "Case Report: A rare presentation of prostate cancer with peritoneal carcinomatosis and malignant ascites complicated by tumor lysis syndrome." F1000Research 11 (August 18, 2022): 957. http://dx.doi.org/10.12688/f1000research.121639.1.

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Background: Only 32 cases of prostate cancer with peritoneal carcinomatosis and ascites have currently been reported in the literature. We present the first reported case of prostate cancer with peritoneal carcinomatosis and malignant ascites whose treatment was complicated by tumor lysis syndrome along with a literature review evaluating similar cases. Case: We present a rare case of a 78-year-old retired Caucasian male with recurrent metastatic prostate cancer and malignant ascites. He had previously received definitive radiotherapy for localized prostate cancer but presented with bilateral

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Brant, Cesar Q., Mario R. Silva Jr., Erica P. Macedo, Claudio Vasconcelos, Natalina Tamaki, and M. Lucia G. Ferraz. "The value of adenosine deaminase (ADA) determination in the diagnosis of tuberculous ascites." Revista do Instituto de Medicina Tropical de São Paulo 37, no. 5 (1995): 449–53. http://dx.doi.org/10.1590/s0036-46651995000500011.

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In order to evaluate the role of the determination of adenosine deaminase activity (ADA) in ascitic fluid for the diagnosis of tuberculosis, 44 patients were studied. Based on biochemical, cytological, histopathological and microbiological tests, the patients were divided into 5 groups: G1 - tuberculous ascites (n = 8); G2 - malignant ascites (n = 13); G3 - spontaneous bacterial peritonitis (n = 6); G4 - pancreatic ascites (n = 2); G5 - miscelaneous ascites (n = 15). ADA concentration were significantly higher in G1 (133.50 ± 24.74 U/l) compared to the other groups (G2 = 41.85 ± 52.07 U/l; G3

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JAIN, Tanvi, Sant RAM, Hemanth KUMAR, Atul SAROCH, Vishal SHARMA, and Harjeet SINGH. "ASCITIC AND SERUM LEVELS OF TUMOR BIOMARKERS (CA 72-4, CA 19-9, CEA AND CA 125) IN DISCRIMINATION OF CAUSE OF ASCITES: A PROSPECTIVE STUDY." Arquivos de Gastroenterologia 59, no. 2 (2022): 198–203. http://dx.doi.org/10.1590/s0004-2803.202202000-37.

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ABSTRACT Background: The role of ascitic and serum levels of various tumour biomarkers in the discrimination of cause of ascites is not well established. Objective: To evaluate the role of serum and ascitic levels of tumor biomarkers (CA 72-4, CA 19-9, CEA and CA 125) in discrimination of cause of ascites. Methods: A prospective study was conducted in consecutive patients presenting with ascites. Serum and ascitic levels of CA 19-9, CA 125, CA 72-4 and carcinoembryonic antigen (CEA) were determined at the presentation. The patients with cirrhotic ascites, tuberculous peritonitis (TBP) and peri

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Aleshikova, O. I., N. A. Babaeva, E. V. Gerfanova, et al. "Ovarian cancer, malignant ascites and microenvironment. Literature review." Sechenov Medical Journal 14, no. 2 (2023): 21–30. http://dx.doi.org/10.47093/2218-7332.2023.14.2.21-30.

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Ovarian cancer (OC) is a heterogenous disease in terms of genetic mutations and tumor phenotypes and can be divided into I and II types. Type II high grade tumors are more common, accompanied by ascites, and are the main cause of cancer-related death in women. OC associated ascites is considered as valuable source of tumor material containing a wide range of dissolved components and cell populations. Over the past decades, the cellular and acellular components of ascites have been studied, but its effect on chemoresistance and the development of metastasis continues to be studied. This review

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Subhani, Mohsan, Abhishek Sheth, Naaventhan Palaniyappan, Peuish Sugathan, Emilie A. Wilkes, and Guruprasad P. Aithal. "Diagnostic accuracy of serum ascites albumin gradient (SAAG) in a contemporary unselected medical cohort." Journal of International Medical Research 50, no. 11 (2022): 030006052211403. http://dx.doi.org/10.1177/03000605221140310.

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Objectives To describe the different aetiologies of ascites and test the validity of serum ascites albumin gradient (SAAG) and cytology in a contemporary unselected medical cohort. Methods All adult patients admitted to Nottingham University Hospitals, UK, between 1 May 2013 and 30 April 2018 with new-onset radiologically-confirmed ascites were included. Data were analysed to determine the distribution of different aetiologies of ascites and the diagnostic accuracy of SAAG in portal hypertension and cytology in malignancy as underlying causes of ascites. Results Over 5 years, 286 patients pres

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Alexandrakis, M. G., J. Moschandrea, D. S. Kyriakou, R. Alexandraki, and E. Kouroumalis. "Use of a Variety of Biological Parameters in Distinguishing Cirrhotic from Malignant Ascites." International Journal of Biological Markers 16, no. 1 (2001): 45–49. http://dx.doi.org/10.1177/172460080101600106.

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Twenty-two different protein measurements were taken in the serum and ascitic fluid of fifty consecutive patients in an attempt to investigate which tests are the most reliable for the differential diagnosis of ascites. Serum and ascitic fluid total proteins (TPR), albumin (ALB), lactate (LAC), ferritin (FER), C3 and C4 complement factors, C-reactive protein (CRP), ceruloplasmin (CER), α2-macroglobulin (α2MG), haptoglobin (HAP), α1-antitrypsin (α1AT), α1-acid glycoprotein (α1AG), transferrin (TRF), immunoglobulins IgG, IgA, IgM and cytokines such as interleukin-1α (IL-1α), interleukin-1α (IL-1

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Fakhri, Rasha Th, Ahmed M. Muhi, Mohammed R. Al-Hilli, and Tharwat I. Sulaiman. "Abdominal computed tomography findings in patients with exudative ascites." Journal of the Faculty of Medicine Baghdad 59, no. 2 (2017): 108–11. http://dx.doi.org/10.32007/jfacmedbagdad.592113.

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Background: peritoneal cavity can be involved in inflammatory and malignant diseases and using computed tomography (CT) findings of exudative ascites may help in the differentiation.Objectives: 1-Describe CT features in patients with exudative ascites.2-Obtain useful CT findings to differentiate between tuberculous (TB) peritonitis and peritoneal carcinomatosis.Patients &methods: A cross sectional study conducted in Medical City Teaching Complex from September 2009 to September 2010 studied patients with exudative ascites using CT scan and confirmed later with histopathology examination. C

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P., Arun, Gireesh G. N., Jinsha K. A., and Vani Jayaraj. "Tripe palm: a paraneoplastic manifestation of carcinoma stomach." International Journal of Research in Medical Sciences 7, no. 6 (2019): 2439. http://dx.doi.org/10.18203/2320-6012.ijrms20192544.

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Usually gastrointestinal malignancies present with low SAAG ascites. But when there is diffuse liver infiltration following malignancy, high SAAG ascites can occur. So liver infiltration can masquerade as cirrhosis. Malignant acanthosis and tripe palm are the paraneoplastic manifestations seen in GI malignancies. We are reporting a case which was initially managed as a straightforward case of cirrhosis ,but later turned out to be a case with tripe palms, malignant acanthosis and carcinoma stomach as primary with diffuse liver infiltration having high SAAG ascites.

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Amatya, A., A. Rana, and G. Gurung. "Pseudo Meig's syndrome- a case report." Journal of Institute of Medicine Nepal 28, no. 1 (2024): 77–79. http://dx.doi.org/10.59779/jiomnepal.228.

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Introduction: Pseudo-Meig isa condition where other type of tumor asa variant to ovarianfibroma associated with hydrothorax and ascites containing no malignant cells, which resolve after removal of tumor. Case Report: This case concerns Pseudo-Meigs' in a 34year old lady with 3 months history of abdominal pain and distension due to ascites and pelvic mass along with massive right pleural effusion who underwent thoracocentesis and total abdominal hysterectomy with bilateral salphingooophorectomy and total omentectomy for ovarian malignancy histologically proven to be papillary adenocarcinoma wi

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C Markal, Asena, Bahram Dideban, Anisha Memdani, Kanika Rathi, and Naveen Baskaran. "A rare case of malignancy-associated ascites with no identifiable cause in a 29-year-old female with BRCA1 mutation." Journal of Case Reports and Images in Oncology 9, no. 1 (2023): 27–31. http://dx.doi.org/10.5348/100122z10am2023cr.

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Introduction: We present a challenging case of a 29-year-old female with a detected Breast Cancer gene 1 (BRCA1) gene mutation who presented to us with an ascites the cause of which remained undiscovered even after appropriate testing. Case Report: A 29-year-old female presented with a five-month history of worsening intermittent abdominal pain which recently became constant and worsened in intensity without any identifiable trigger. She also had complaints of constipation for the past 2–3 days. Her past medical history was positive for (BRCA1) mutation which was tested after her mother’s diag

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Uno, Kaname, Shohei Iyoshi, Masato Yoshihara, et al. "Metastatic Voyage of Ovarian Cancer Cells in Ascites with the Assistance of Various Cellular Components." International Journal of Molecular Sciences 23, no. 8 (2022): 4383. http://dx.doi.org/10.3390/ijms23084383.

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Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy and has a unique metastatic route using ascites, known as the transcoelomic root. However, studies on ascites and contained cellular components have not yet been sufficiently clarified. In this review, we focus on the significance of accumulating ascites, contained EOC cells in the form of spheroids, and interaction with non-malignant host cells. To become resistant against anoikis, EOC cells form spheroids in ascites, where epithelial-to-mesenchymal transition stimulated by transforming growth factor-β can be a key path

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Bose, Katrin, Florian G. Scurt, Cosima Thon, et al. "Factors Affecting Performance of DNA Methylation as a Potential Biomarker in Ascites for Peritonitis and Peritoneal Carcinomatosis." Journal of Gastrointestinal and Liver Diseases 32, no. 2 (2023): 206–15. http://dx.doi.org/10.15403/jgld-4710.

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Background and Aims: Despite limited sensitivity, the gold standard for the diagnosis of malignant cells in ascites is still cytology. The aim of this prospective proof-of-principle study was to evaluate DNA methylation as a molecular tool for the differential diagnosis of benign and malignant ascites. Methods: A cohort of 79 patients with malignant and non-malignant ascites was prospectively enrolled. Ascites was assessed by cytopathological and laboratory examination. Cell pellets obtained by centrifugation were analyzed for differences in DNA methylation of of long interspersed nuclea

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Rickard, Brittany P., Christina Conrad, Aaron J. Sorrin, et al. "Malignant Ascites in Ovarian Cancer: Cellular, Acellular, and Biophysical Determinants of Molecular Characteristics and Therapy Response." Cancers 13, no. 17 (2021): 4318. http://dx.doi.org/10.3390/cancers13174318.

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Ascites refers to the abnormal accumulation of fluid in the peritoneum resulting from an underlying pathology, such as metastatic cancer. Among all cancers, advanced-stage epithelial ovarian cancer is most frequently associated with the production of malignant ascites and is the leading cause of death from gynecologic malignancies. Despite decades of evidence showing that the accumulation of peritoneal fluid portends the poorest outcomes for cancer patients, the role of malignant ascites in promoting metastasis and therapy resistance remains poorly understood. This review summarizes the curren

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De Simone, Gustavo G. "Treatment of Malignant Ascites." Progress in Palliative Care 7, no. 1 (1999): 10–16. http://dx.doi.org/10.1080/09699260.1999.11746825.

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Prieto, Mart�n, Mar�a Jos� G�mez-Lech�n, Melchor Hoyos, Jose V. Castell, Domingo Carrasco, and Joaqu�n Berenguer. "Diagnosis of malignant ascites." Digestive Diseases and Sciences 33, no. 7 (1988): 833–38. http://dx.doi.org/10.1007/bf01550972.

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40

Rosenberg, Stefanie M. "Palliation of Malignant Ascites." Gastroenterology Clinics of North America 35, no. 1 (2006): 189–99. http://dx.doi.org/10.1016/j.gtc.2005.12.006.

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Walton, Lyle, and James M. Nottingham. "Palliation of Malignant Ascites." Journal of Surgical Education 64, no. 1 (2007): 4–9. http://dx.doi.org/10.1016/j.cursur.2006.08.008.

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42

Chung, Michael, and Peter Kozuch. "Treatment of Malignant Ascites." Current Treatment Options in Oncology 9, no. 2-3 (2008): 215–33. http://dx.doi.org/10.1007/s11864-008-0068-y.

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Hodge, Caitlin, and Brian D. Badgwell. "Palliation of malignant ascites." Journal of Surgical Oncology 120, no. 1 (2019): 67–73. http://dx.doi.org/10.1002/jso.25453.

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Gwee, Yong Xiang, Daryl Chia, Leonardo Provenzano, et al. "Malignant ascites as a marker of peritoneal carcinomatosis burden in patients with colorectal and gastroesophageal cancer." Journal of Clinical Oncology 41, no. 4_suppl (2023): 455. http://dx.doi.org/10.1200/jco.2023.41.4_suppl.455.

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455 Background: Malignant ascites occurs frequently in patients with gastric cancer (GC) and colorectal cancer (CRC) with peritoneal metastasis (PM). The presence of PM and malignant ascites have been independently reported to confer resistance to systemic therapy and poorer prognosis. However, the occurrence of malignant ascites as a function of increasing peritoneal carcinomatosis burden has been less studied and reported. Methods: We reviewed prospective cohorts of gastric cancer and colorectal cancer patients with PM. The first cohort was a prospective group of GCPM patients receiving bi-d

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ABDURAKHMONOV, Jurabek Amrilloevich, Nodir Makhammatkulovich RAHIMOV, and Shakhnoza Shavkatovna SHAKHANOVA. "MODERN VIEW ON ASCITE IN OVARIAN CANCER." Journal of biomedicine and practice 7, no. 4 (2022): 5. https://doi.org/10.5281/zenodo.7027279.

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Malignant ascites is often found in ovarian cancer, moreover, about 10% of patients suffer from recurrent ovarian cancer. More than a third of patients with ovarian cancer have ascites while diagnosed, and almost all has ascites when it relapses. The presence of ascites correlates with the peritoneal spread of ovarian cancer and is associated with a poor prognosis of the disease. Malignant ascites acts as a reservoir of a complex mixture of soluble factors and cellular components that provide a tumor-stimulating microenvironment for tumor cells. Tumor cells in OV associated malignant ascites c

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Basha, Jahangeer, Sundeep Lakhtakia, Raghavendra Yarlagadda, et al. "Gastric outlet obstruction with ascites: EUS-guided gastro-enterostomy is feasible." Endoscopy International Open 09, no. 12 (2021): E1918—E1923. http://dx.doi.org/10.1055/a-1642-7892.

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Abstract Background and study aims Endoscopic ultrasound-guided gastro-enterostomy(EUS-GE) is a recently described novel minimally invasive endoscopic procedure for patients having malignant gastric outlet obstruction (GOO). The safety of EUS-GE in the presence of ascites with GOO is not known. The objective of the study was to evaluate the feasibility and safety of EUS-GE in patients with GOO and ascites. Patients and methods Consecutive patients with GOO who underwent EUS-GE between January 2019 and March 2021 constituted the study population. EUS-GE was performed using either EPASS or free-

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Samankan, Shabnam, Mehran Taherian, Maryam Aghighi, and David Crossland. "Pigs in a blanket: an unusual presentation of malignant ascites in prostatic adenocarcinoma." BMJ Case Reports 12, no. 11 (2019): e230899. http://dx.doi.org/10.1136/bcr-2019-230899.

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Malignant ascites in prostatic acinar adenocarcinoma is very rare. We present an 84-year-old man with a rare malignant ascites due to prostatic adenocarcinoma demonstrating hepatoid differentiation by immunohistochemistry. The patient was diagnosed with the malignant ascites due to metastatic prostatic adenocarcinoma. We identified the unique cytological feature of envelopment of tumour cell clusters by benign mesothelial monolayers.

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Emoto, S., J. Kitayama, H. Ishigami, et al. "Analysis of pO2 in malignant ascites of patients with peritoneal dissemination of gastric cancer." Journal of Clinical Oncology 29, no. 4_suppl (2011): 63. http://dx.doi.org/10.1200/jco.2011.29.4_suppl.63.

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63 Background: Peritoneal metastasis is considered to develop from carcinoma cells detached from the serosal surface of the primary site and dispersed in the peritoneal cavity. And oxygen is one of the most important environmental factors for tumor development. To investigate the oxygenation condition in the abdominal cavity, that is largely unknown, we collected ascitic fluid from patients with peritoneal dissemination of gastric cancer and measured pO2 of it. Methods: In 19 patients with peritoneal dissemination of gastric cancer, who had a considerable amount of ascites and was receiving sy

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Kosaka, Nobuaki, Kiyoshi Hasegawa, Kaori Kiuchi, et al. "Cytological Findings of Ascitic Fluid with a Malignant Ovarian Steroid Cell Tumor: A Case Report and Literature Review." Acta Cytologica 61, no. 2 (2017): 165–71. http://dx.doi.org/10.1159/000458750.

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Background: Ovarian steroid cell tumors (SCTs) are rare and usually benign, although 25-43% are reportedly malignant. The cytologic findings of these rare ovarian tumors have almost never been reported. Case: We report a rare case of a malignant ovarian SCT with peritoneal dissemination and malignant ascites in a 40-year-old woman. Her tumor was classified as stage IIB (pT2bNoM0) according to the FIGO (International Federation of Gynecology and Obstetrics) classification system, and she was treated with adjuvant chemotherapy following staging laparotomy. Cytology of the ascitic fluid revealed

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Miao, Bolin. "Exploring the interactions between peritoneal dendritic cells and T cells: Implications for cancer metastasis." Theoretical and Natural Science 59, no. 1 (2024): 152–64. http://dx.doi.org/10.54254/2753-8818/59/20241388.

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Abstract. Ovarian Cancer (OC) is a formidable challenge as a gynecological malignancy with ascites, the abnormal accumulation of fluid in the peritoneal cavity, serving as a clinical hallmark of advancement and metastasis. While OC immune analyses focus on solid tumors, little is known about malignant ascites inhabitants during peritoneal metastasis. Here, we focused on a single-cell landscape of the OC ecosystem in malignant ascites with comparison to tumor sites. Our data analysis reveals that compared to the immunosuppressed tumor, ascites contained less exhausted, more memory-like T cells,

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