Academic literature on the topic 'Maligne cellen'

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Journal articles on the topic "Maligne cellen"

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Lewis, Ellen. "Optimiser les soins palliatifs précoces aux patients atteints d’un cancer hématologique recevant une greffe de cellules souches : rôle de l’infirmière praticienne." Canadian Oncology Nursing Journal 30, no. 4 (2020): 246–52. http://dx.doi.org/10.5737/23688076304246252.

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La greffe de cellules souches hématopoïétiques (GCSH) est une approche thérapeutique intensive des hémopathies malignes qui s’accompagne d’un important risque de morbidité et de mortalité. Malgré la lueur d’espoir qu’elle apporte aux patients, les traitements sont longs et pénibles, tant du point de vue physique que psychosocial. Habituellement, la greffe de cellules souches hématopoïétiques a une visée curative qui laisse peu de place à un partenariat éventuel avec les services de soins palliatifs et, lorsque ces derniers sont proposés, il est souvent trop tard pour en tirer un bénéfice notab
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Mercier, Marie, Emmanuelle Bocquet, Michel Danguy, and Monique-Marie Rousset. "Planification des soins bucco-dentaires et des traitements ODF chez les enfants atteints d’une hémopathie maligne." L'Orthodontie Française 82, no. 3 (2011): 299–306. http://dx.doi.org/10.1051/orthodfr/2011133.

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Problématique : la maladie cancéreuse concerne en France 1 à 3 % des enfants et représente la deuxième cause de mortalité la plus fréquente chez les moins de 15 ans. Les hémopathies malignes sont les plus nombreuses et, si la mortalité tend à diminuer, elle survient le plus souvent à la suite d’une infection dite « opportuniste ». Celle-ci se développe à partir de foyers latents non éradiqués, délétères chez ces patients et dont l’origine peut être dentaire. Ce risque infectieux est insuffisamment diagnostiqué à l’hôpital et concerne chirurgiens-dentistes et orthodontistes. Objectifs : les chi
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Gesbert, Cédric, Cécile Torregrosa, and Marie-France Mamzer. "De l’incidentalome à la découverte secondaire." médecine/sciences 36, no. 11 (2020): 1054–58. http://dx.doi.org/10.1051/medsci/2020188.

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Le terme incidentalome, créé en 1982, s’est, depuis, diffusé dans la littérature médicale. Il ne semble cependant pas exister de définition précise pour décrire ce qu’est un incidentalome. Dans les usages initiaux, l’incidentalome désignait une masse détectée à l’occasion d’un examen d’imagerie prescrit à visée diagnostique sans qu’un lien ne soit déterminé avec le motif de réalisation de l’examen. La qualification d’« incidentalome » de cette masse n’apportait aucune précision sur sa nature, celle-ci pouvant être située dans de nombreuses zones anatomiques, être sécrétante ou non, être bénign
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Greveling, K., M. Wakkee, T. Nijsten, R. R. van den Bos, and L. Hollestein. "046 Epidemiology of lentigo maligna and lentigo maligna melanoma in the Netherlands, 1989 – 2013." Journal of Investigative Dermatology 136, no. 9 (2016): S168. http://dx.doi.org/10.1016/j.jid.2016.06.063.

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Ammor, Y., M. Laaouze, K. Saoud, et al. "UNE TUMEUR DE LOVAIRE RARE: LA TUMEUR DE BRENNER (A PROPOS DUN CAS)." International Journal of Advanced Research 8, no. 12 (2020): 1082–87. http://dx.doi.org/10.21474/ijar01/12256.

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Introduction: Les tumeurs de Brenner de l’ovaire representent 1 a 2% de toutes les tumeurs ovariennes.Observation : Nous rapportons le cas d’une femme de 60 ans G4P4 , sans antecedents pathologiques notables ,consulte pour des douleurs pelviennes chroniques dont L’echographie pelvienne objective la presence d’une masse latero-uterine gauche et retro-uterine faisant 71*57 mm non dopplerisee avec fine lame d’epanchement intraperitoneal, et a la TDM AP : processus tumoral a composante mixte kystique et tissulaire et calcique heterogene retro uterin enclave dans le cul de sac de Dou
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Leslie, Mitch. "The good side of a maligned protein." Journal of Cell Biology 156, no. 1 (2002): 11. http://dx.doi.org/10.1083/jcb1561rr4.

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Pokharel, Saraswati, Umesh C. Sharma, and Yigal M. Pinto. "Left ventricular hypertrophy: virtuous intentions, malign consequences." International Journal of Biochemistry & Cell Biology 35, no. 6 (2003): 802–6. http://dx.doi.org/10.1016/s1357-2725(02)00344-8.

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Hoy, Nathan, Joyce Wong, Muhammad Mahmood, and Alain Brassard. "Basaloid Squamous Cell Carcinoma of the Nasal Septum Presenting as a Primary Cutaneous Lesion." Journal of Cutaneous Medicine and Surgery 16, no. 5 (2012): 375–77. http://dx.doi.org/10.1177/120347541201600520.

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Background: Basaloid squamous cell carcinoma is a rare aggressive variant of squamous cell carcinoma, with a predilection for the head and neck region. There are only two case reports in the literature documenting a nasal cavity squamous cell carcinoma presenting as a primary cutaneous lesion. Objective: We report a rare case of nasal cavity basaloid squamous cell carcinoma presenting initially as a nasal bridge mass. Two initial biopsies revealed features consistent with basal cell carcinoma and basosquamous cell carcinoma, respectively. Result: Final surgical pathology showed extensive invas
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O'Hern, K., M. Chambers, and M. Chapman. "650 Imiquimod spares disfiguring surgery for large facial lentigo maligna." Journal of Investigative Dermatology 140, no. 7 (2020): S88. http://dx.doi.org/10.1016/j.jid.2020.03.662.

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Leuschner, I., G. Calaminus, and U. Göbel. "Yolk sac tumor components in recurrences of children with teratoma: is the maligne component already in the primary?" Pathology - Research and Practice 200, no. 4 (2004): 360. http://dx.doi.org/10.1016/s0344-0338(04)80787-8.

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Dissertations / Theses on the topic "Maligne cellen"

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Saab-Estephan, Marie-Belle. "Rheology and photonics of complex biological systems." Thesis, Montpellier 2, 2010. http://www.theses.fr/2010MON20043.

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La rhéologie et la photonique de divers systèmes biologiques complexes allant des protéines jusqu'aux bactéries et cellules ont été étudiées dans cette thèse. Ces travaux se basent sur deux grands thèmes, où le premier traite la modification des surfaces solides avec des molécules biologiques tandis que le second se concentre sur l'étude des effets des différentes drogues sur des cellules malignes, et non malignes par des techniques microscopiques complémentaires. Dans ce travail, des matrices orientées de films de polyélectrolytes/membrane pourpre ont été produites et étudiées en fonction de
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Schenka, Natalia Guimarães de Moraes. "Avaliação imunoistoquimica de celulas mioepiteliais no diagnostico diferencial de lesões benignas e malignas da mama." [s.n.], 2006. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310141.

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Orientador: Jose Vassalo<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-07T05:09:42Z (GMT). No. of bitstreams: 1 Schenka_NataliaGuimaraesdeMoraes_D.pdf: 3809756 bytes, checksum: d4d7db8aeacfcd3c285cdee5b7c0a182 (MD5) Previous issue date: 2006<br>Resumo: O sistema ductal da mama é revestido por duas camadas de células: uma constituída de células epiteliais luminais e outra de células mioepiteliais (CME). A identificação das CMEs é de grande importância na rotina em patologia cirúrgica, já que estas estão presentes
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Hutschenreuther, Antje, Marina Bigl, Nasr Y. A. Hemdan, Tewodros Debebe, Frank Gaunitz, and Gerd Birkenmeier. "Modulation of GLO1 expression affects malignant properties of cells." Universitätsbibliothek Leipzig, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-217965.

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The energy metabolism of most tumor cells relies on aerobic glycolysis (Warburg effect) characterized by an increased glycolytic flux that is accompanied by the increased formation of the cytotoxic metabolite methylglyoxal (MGO). Consequently, the rate of detoxification of this reactive glycolytic byproduct needs to be increased in order to prevent deleterious effects to the cells. This is brought about by an increased expression of glyoxalase 1 (GLO1) that is the rate-limiting enzyme of the MGO-detoxifying glyoxalase system. Here, we overexpressed GLO1 in HEK 293 cells and silenced it in MCF-
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Fuchs, Iris Judith. "Untersuchungen zur chemischen Transformation von intestinalen Epithelzellen der Ratte und des Menschen durch 2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridin." Phd thesis, Universität Potsdam, 2006. http://opus.kobv.de/ubp/volltexte/2007/1180/.

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Oliveira, Rodrigo Vismari de 1980. "Expressão de antígenos de células-tronco neoplásicas avaliada por imunoistoquímica em neoplasias malignas da mama humana : caracterização e possíveis aplicações clínicas." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312484.

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Orientador: André Almeida Schenka<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-26T04:27:58Z (GMT). No. of bitstreams: 1 Oliveira_RodrigoVismaride_M.pdf: 21638955 bytes, checksum: 23e75fa9b7ece343f54fcfd2dcaea03c (MD5) Previous issue date: 2014<br>Resumo: O câncer de mama é a neoplasia maligna mais frequente no mundo. A hipótese da célula-tronco neoplásica (CTN) é um novo paradigma de carcinogênese. A imunoistoquímica (IHC) é um método de escolha para detecção de CTN em tecidos parafinizados, com as seguint
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Jain, Sarika. "Role and regulation of the heat shock proteins Hsp90 alpha and beta in Multiple Myeloma." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2008. http://dx.doi.org/10.18452/15809.

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Das Multiple Myelom (MM) ist eine hämatologische Erkrankung, welche sich durch eine Akkumulation von malignen Plasmazellen im Knochenmark auszeichnet und eine gestörte Hämatopoiese und Osteolyse zur Folge hat. Komplexe molekulare Interaktionen zwischen MM-Zellen und der Mikroumgebung/Nische im Knochenmark (bone marrow microenvironment, BMM) führen zu einer Aktivierung von verschiedenen Wachstums-, Überlebens- und anti-apoptotischen Signalwegen, die zur Entstehung bzw. Wirkstoffresistenz von MM-Zellen beitragen. IL-6R/STAT3, Ras/MAPK und PI3K/Akt sind die drei wichtigsten Signalwege, die mit de
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Hutschenreuther, Antje, Marina Bigl, Nasr Y. A. Hemdan, Tewodros Debebe, Frank Gaunitz, and Gerd Birkenmeier. "Modulation of GLO1 expression affects malignant properties of cells." MDPI, 2016. https://ul.qucosa.de/id/qucosa%3A15256.

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The energy metabolism of most tumor cells relies on aerobic glycolysis (Warburg effect) characterized by an increased glycolytic flux that is accompanied by the increased formation of the cytotoxic metabolite methylglyoxal (MGO). Consequently, the rate of detoxification of this reactive glycolytic byproduct needs to be increased in order to prevent deleterious effects to the cells. This is brought about by an increased expression of glyoxalase 1 (GLO1) that is the rate-limiting enzyme of the MGO-detoxifying glyoxalase system. Here, we overexpressed GLO1 in HEK 293 cells and silenced it in MCF-
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Decaudin, Camille. "Impacts fonctionnels et conséquences sur la différenciation hématopoïétique d’une mutation somatique récurrente du gène PU.1/SPI1 identifiée dans la macroglobulinémie de Waldenström A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASL004.

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Le facteur de transcription PU.1/SPI1 de la famille ETS est un régulateur majeur de l'hématopoïèse, et de la différenciation des cellules souches, myéloïdes et lymphoïdes. Précédemment identifié comme un suppresseur de tumeur dans les malignités myéloïdes humaines, nous avons identifié une mutation somatique récurrente faux sens (Q226E) du gène PU.1 dans la macroglobulinémie de Waldenström, un syndrome lymphoprolifératif à cellules B. La mutation affecte la liaison à l'ADN de la protéine et permet au mutant de se lier et d'activer plus fréquemment les régions promotrices par rapport à la proté
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Honda, Suzana Terumi. "Influência de fibroblastos de linfonodo axilar de pacientes com câncer de mama na expressão gênica de células mamárias malignas MDA-MB231 e MCF-7." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5155/tde-04042016-095339/.

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O comportamento do câncer de mama pode ser influenciado pela interação entre células tumorais e estromais que infiltram e circundam o tumor. Acredita-se também que as células que compõem o microambiente linfonodal possam influenciar o perfil da expressão gênica de células mamárias malignas MDA-MB231, induzindo ou inibindo o desenvolvimento de metástase regional. Para avaliar essa possibilidade, células MDA-MB231 foram co-cultivadas com fibroblastos obtidos de linfonodos comprometidos ou não comprometidos de pacientes com câncer de mama, separadas por membranas porosas por 72 horas. O perfil da
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Benvenuti, Ticiana Thomazine. "Influência de células epiteliais mamárias malignas na expressão gênica de células estromais originárias de linfonodo axilar comprometido ou não comprometido de pacientes com câncer de mama." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5155/tde-08072008-105031/.

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O desenvolvimento da metástase depende, entre outros fatores de um microambiente propício e é possível que as células do câncer de mama influenciem o perfil da expressão gênica das células estromais, tanto no tumor primário como no linfonodo regional. Para estudar este último evento obtivemos fibroblastos de linfonodos comprometidos (n=3) ou não (n=3) de pacientes com câncer de mama, os quais foram co-cultivados com células de câncer de mama MDA-MB-231, separados fisicamente por membranas porosas por 72 horas. O perfil da expressão gênica foi determinado utilizando-se uma plataforma de cDNA mi
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Books on the topic "Maligne cellen"

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Malignant effusions: A multimodal approach to cytologic diagnosis. Igaku-Shoin, 1994.

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North Atlantic Treaty Organization. Scientific Affairs Division (Corporate Author) and Asterios S. Tsiftsoglou (Editor), eds. Tumor Biology: Regulation of Cell Growth, Differentiation, and Genetics in Cancer (Nato a S I Series Series H, Cell Biology). Springer-Verlag Telos, 1996.

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1948-, Tsiftsoglou Asterios S., North Atlantic Treaty Organization. Scientific Affairs Division., and NATO Science Institute "Regulation of Cell Growth, Differentiation, and Genetics in Cancer" (1995 : Porto Karras, Chalkidikē, Greece), eds. Tumor biology: Regulation of cell growth, differentiation, and genetics in cancer. Springer, 1996.

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1933-, Doerfler Walter, and Böhm P, eds. Malignant transformation by DNA viruses: Molecular mechanisms. VCH, 1992.

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Doerfler, Walter. Malignant Transformation by DNA Viruses: Molecular Mechanisms. Vch Pub, 1992.

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(Editor), Bernhard Holzmann, and Hermann Wagner (Editor), eds. Leukocyte Integrins in the Immune System & Malignant Disease. Springer, 1998.

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A, Grand R. J., ed. Viruses, cell transformation, and cancer. Elsevier, 2001.

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KAS, GERT-JAN L. Drug Resistance in Leukemia and Lymphoma: The Clinical Value of Laboratory Studies. Taylor & Francis, 1993.

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Kaspers, G. J. L., 1963-, ed. Drug resistance in leukemia and lymphoma: The clinical value of laboratory studies. Harwood Academic Publishers, 1993.

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Book chapters on the topic "Maligne cellen"

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Açar, Gülay. "Surgical Anatomy of the Tonsils." In Oral and Maxillofacial Surgery. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.93038.

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The tonsils represent a circular band of mucosa associated with lymphoid tissues, Waldeyer’s ring, which is located at the entrance of the upper aerodigestive tract, with a significant role in the immune defense system. Waldeyer’s ring is composed of the pharyngeal, tubal, palatine, and lingual tonsils acting as secondary lymphoid tissues. Particularly, the palatine tonsils are the largest of the tonsils with deep branching crypts and contain B and T lymphocytes and M cell which plays a role in the uptake and transport of antigens. Because of the tonsil enlargement during childhood, upper airway obstruction and obstructive sleep apnea syndrome are mostly seen. Knowledge of the surgical anatomy of the tonsils and variations of the neurovascular and muscular structures around it allows optimal choice of surgical technique to avoid iatrogenic complications during tonsillectomy. Recent medical studies reported that a detailed understanding of the anatomic risk factors in upper airway obstruction allows to predict treatment response to surgical intervention. Due to the penetration of benign or malign lesions of the tonsil into the lateral wall of the pharynx, transoral robotic approach to this region is necessary to identify the surgical anatomic landmarks which are required to perform safe and effective surgical intervention.
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Hopkins, Frances, and Philip Nightingale. "Effects of Ocean Acidification on the Marine Source of Atmospherically Active Trace Gases." In Ocean Acidification. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199591091.003.0016.

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A wide range of trace gases, including dimethyl sulphide (DMS) and organohalogens, are formed in the surface oceans via biological and/or photochemical processes. Consequently, these gases become supersaturated in seawater relative to the overlying marine air, leading to a net flux to the atmosphere. Upon entering the atmosphere, they are subject to rapid oxidation or radical attack to produce highly reactive radical species which are involved in a number of important atmospheric and climatic processes. Organohalogens can affect the oxidizing capacity of the atmosphere by interacting with ozone, with implications for air quality, stratospheric ozone levels, and global radiative forcing. DMS and iodine-containing organohalogens (iodocarbons) can both contribute to direct and indirect impacts of aerosols on climate through the production of new particles and cloud condensation nuclei (CCN) in the clean marine atmosphere. Therefore, marine trace gases are considered a vital component of the earth’s climate system, and changes in the net production rate and subsequent sea-to-air flux could have an impact on globally important processes. In recent years, attention has turned to the impact that future ocean acidification may have on the production of such gases, with the greatest focus on DMS and organohalogens. In this chapter, the current state-of-the-art in this growing area of research is outlined. The oceans are a major source of sulphur (S), an element essential to all life, and marine emissions of the gas DMS (chemical formula (CH3)2S) represent a key pathway in the global biogeochemical sulphur cycle. The surface oceans are supersaturated with DMS relative to the atmosphere, resulting in a oneway flux from sea to air (Lovelock et al. 1972; Watson and Liss 1998). DMS is a breakdown product of the biogenically produced dimethyl sulphoniopropionate (DMSP): . . . (CH3)2S+CH2CH2COO- → (CH3)2S + CH2CHCOOH (acrylic acid) (11.1) . . . Single-celled marine phytoplankton are the chief producers of DMSP, and this reaction is catalysed intra- and extracellularly by the enzyme DMSP-lyase (Malin et al. 1992; Liss et al. 1997). The capacity of phytoplankton to produce DMSP varies between species, with prymnesiophytes considered to be the most prolific (Malin et al. 1992 ; Liss et al. 1997 ; Watson and Liss 1998).
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Conference papers on the topic "Maligne cellen"

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da Silva, Priscilla Veiga Pereira, Vera Lúcia Mota da Fonseca, Roberto de Azevedo Antunes, and Afranio Coelho-Oliveira. "Tumor ovariano das células da granulosa tipo adulto: relato de caso." In 44° Congresso da SGORJ - XXIII Trocando Ideias. Zeppelini Editorial e Comunicação, 2020. http://dx.doi.org/10.5327/jbg-0368-1416-2020130209.

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Introdução: Os tumores de células da granulosa (TCG) são neoplasias ovarianas malignas raras, porém são as mais frequentes entre as neoplasias estromais do cordão sexual. São responsáveis por 3 a 5% de todas as neoplasias ovarianas. O TCG tipo adulto (TCGA) apresenta maior prevalência no climatério (média de 50 anos). Em razão do hiperestrogenismo causado pelo tumor, os sintomas variam de acordo com a faixa etária. O tratamento e o estadiamento são cirúrgicos. A imuno-histoquímica auxilia na elucidação diagnóstica. Em razão da grande probabilidade de recidiva, é necessário um seguimento a long
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Roume, M., S. Azogui-Lévy, G. Lescaille, V. Descroix, and J. Rochefort. "Connaissances, attitudes et pratiques en pathologie de la muqueuse buccale des chirurgiens-dentistes en France, enquête nationale." In 66ème Congrès de la SFCO. EDP Sciences, 2020. http://dx.doi.org/10.1051/sfco/20206602010.

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Introduction : Les Chirurgiens-dentistes (CD) ont pour rôle d’identifier et de diagnostiquer les pathologies de la muqueuse orale (PMO), de les prendre en charge ou d’orienter les patients vers les spécialistes adéquats. Une importante errance diagnostique des patients atteints de PMO a été mise en évidence, pouvant être à l’origine d’une perte de chance notamment dans les cas de carcinomes épidermödes ou d’hémopathies malignes (Scully et al 1999, Albisetti et al, 2016). Ce constat s’accompagne d’études internationales portant sur le comportement des CD face aux PMO (Ergun et al 2009, Sardella
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