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Journal articles on the topic 'Malondialdehyde. eng'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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1

Roestijawati, Nendyah, and Yudhi Wibowo. "Malondialdehyde Meningkatkan Tingkat Antigen Khusus Prostat di Antara Pekerja Bengkel Mobil." Buletin Penelitian Kesehatan 49, no. 1 (2021): 57–62. http://dx.doi.org/10.22435/bpk.v0i0.3832.

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Cadmium (Cd) is one of the environmental factors that can cause prostate cancer. Cadmium can induces metallothionein (MT) in several tissues that functions to carry out an intracellular detoxification procession by binding to Cd. Exposure of Cd can cause an increase in reactive oxygen species which will cause lipid peroxidation with the end product being malondialdehyde (MDA). The research aims to determine the correlation between MT, MDA and prostate specific antigen (PSA) among auto body repair workers. The study used a cross sectional design involving 32 auto body repair workers and their a

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Roestijawati, Nendyah, and Yudhi Wibowo. "Malondialdehyde Meningkatkan Tingkat Antigen Khusus Prostat di Antara Pekerja Bengkel Mobil." Buletin Penelitian Kesehatan 49, no. 1 (2021): 57–62. http://dx.doi.org/10.22435/bpk.v49i1.3832.

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Cadmium (Cd) is one of the environmental factors that can cause prostate cancer. Cadmium can induces metallothionein (MT) in several tissues that functions to carry out an intracellular detoxification procession by binding to Cd. Exposure of Cd can cause an increase in reactive oxygen species which will cause lipid peroxidation with the end product being malondialdehyde (MDA). The research aims to determine the correlation between MT, MDA and prostate specific antigen (PSA) among auto body repair workers. The study used a cross sectional design involving 32 auto body repair workers and their a

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Crnogaj, M., R. Petlevski, V. Mrljak, et al. "Malondialdehyde levels in serum of dogs infected with Babesia canis." Veterinární Medicína 55, No. 4 (2010): 163–71. http://dx.doi.org/10.17221/77/2010-vetmed.

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Babesiosis is a common tick born disease of dogs in tropical and subtropical regions of the world caused by different species of Babesia. The aim of the present study was to confirm the presence of oxidative stress by examining serum malondialdehyde (MDA), an end product of lipid peroxidation, in 35 dogs naturally infected with Babesia canis (B. canis). MDA was examined in 14 healthy dogs as well. Blood smears were prepared from peripheral blood and they showed the presence of B. canis in infected dogs. B. canis was confirmed using the PCR (Polymerase chain reaction) method. On the basis of cl

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Jové, Mariona, Natàlia Mota-Martorell, Irene Pradas, Meritxell Martín-Gari, Victoria Ayala, and Reinald Pamplona. "The Advanced Lipoxidation End-Product Malondialdehyde-Lysine in Aging and Longevity." Antioxidants 9, no. 11 (2020): 1132. http://dx.doi.org/10.3390/antiox9111132.

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The nonenzymatic adduction of malondialdehyde (MDA) to the protein amino groups leads to the formation of malondialdehyde-lysine (MDALys). The degree of unsaturation of biological membranes and the intracellular oxidative conditions are the main factors that modulate MDALys formation. The low concentration of this modification in the different cellular components, found in a wide diversity of tissues and animal species, is indicative of the presence of a complex network of cellular protection mechanisms that avoid its cytotoxic effects. In this review, we will focus on the chemistry of this li

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Merendino, Rosaria Alba, Francesco Salvo, Antonella Saija, et al. "Malondialdehyde in benign prostate hypertrophy: a useful marker?" Mediators of Inflammation 12, no. 2 (2003): 127–28. http://dx.doi.org/10.1080/0962935031000097745.

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Benign prostate hypertrophy (BPH) is the most common benign tumor in men due to obstruction of the urethra and, finally, uremia. Malondialdehyde (MDA) is a product derived from peroxidation of polyunsaturated fatty acids and related esters. Evaluation of MDA in serum represents a non-invasive biomarker of oxidative stress. Prostate-specific antigen (PSA) is a sensitive marker for prostatic hypertrophy and cancer. We analyzed MDA serum levels to evaluate the oxidative stress in BPH. To this end, 22 BPH patients and 22 healthy donors were enrolled. Data show an increase of MDA level in BPH patie

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Hasbullah, Innaka, Z. Wulandari, and D. M. Suci. "Suplemen Jus Daun Afrika (Vernonia amygdalina) dalam Air Minum terhadap Komposisi Kimia dan Kadar Malondialdehid Telur Puyuh (Coturnix coturnix japonica)." Jurnal Ilmu Nutrisi dan Teknologi Pakan 18, no. 2 (2020): 43–48. http://dx.doi.org/10.29244/jintp.18.2.43-48.

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This study aimed to determine the effectiveness of African leaf juice supplements on the chemical properties of quail eggs. This research used 120 quails aged 8 weeks, which divided into 3 treatments and 5 replications. The experimental design used a completely randomized and the treatments were P0 : without the supplementation of African leaf juice as controls, P1: addition of 3 ml head-1 day-1 African leaf juice, and P2: addition of 6 ml head-1 day-1 African leaf juice (P2). The variables observed were moisture, ash, crude protein, ether extract, carbohydrate, malondialdehyde content (MDA),

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Situmorang, Novrina, and Zulham Zulham. "MALONDIALDEHYDE (MDA) (ZAT OKSIDAN YANG MEMPERCEPAT PROSES PENUAAN)." JURNAL KEPERAWATAN DAN FISIOTERAPI (JKF) 2, no. 2 (2020): 117–23. http://dx.doi.org/10.35451/jkf.v2i2.338.

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Malondialdehyde (MDA) is the end product of fat peroxidation due to the breakdown of fatty acid chains which are compounds that toxic to cells. Fat peroxidation is caused by body fat bound to free radicals such as hydroxyl radicals, superoxide anion radicals, and hydrogen peroxide, which are compounds or atoms that have unpaired electrons in their outer orbitals so that they are very reactive to cells or surrounding cell components including lipids. As a result of the lipid peroxidation reaction which is continuous which can cause various diseases and accelerate the aging process, because malo

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McDonald, Joshua D., Eunice Mah, Chureeporn Chitchumroonchokchai, et al. "Co-ingestion of whole eggs or egg whites with glucose protects against postprandial hyperglycaemia-induced oxidative stress and dysregulated arginine metabolism in association with improved vascular endothelial function in prediabetic men." British Journal of Nutrition 120, no. 8 (2018): 901–13. http://dx.doi.org/10.1017/s0007114518002192.

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AbstractReplacing a portion of a glucose challenge with whole eggs (EGG) or egg whites (WHITE) was shown to protect against glucose-induced impairments in vascular function. We hypothesised in the present study that previously observed vasoprotection following co-ingestion of EGG or WHITE with glucose was attributed to limiting postprandial hyperglycaemia-induced oxidative stress that improves NO∙ bioavailability. Prediabetic men completed a randomised, cross-over study in which they ingested isoenergetic meals containing 100 g glucose (GLU), or 75 g glucose with 1·5 EGG, seven WHITE or two eg

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Bachmeier, E., ME Migueles Goitea, JA Linares, et al. "Effect of carboplatin on malondialdehyde as a marker of lipoderoxidation in the submandibular gland of rats." Revista de la Facultad de Odontología 31, no. 2 (2021): 9–13. http://dx.doi.org/10.25014/revfacodont271.2021.31.2.9.

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The objective of the present work was to evaluate the effect of carboplatin (Cp) on submandibular gland homogenate of Wistar rats through the determination of malondialdehyde levels, as the main end product of lipoperoxidation, in an experimental model.Sixteen three-month-old male Wistar rats were used, housed in individual cages, with controlled temperature and lighting and free diet. A completely randomized design was used and two experimental groups were established: 1) Control (C), administering an intraperitoneal dose of saline solution for one day, n: 8, 2) Animals treated with carboplat

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Štikarová, Jana, Roman Kotlín, Tomáš Riedel, et al. "The Effect of Reagents Mimicking Oxidative Stress on Fibrinogen Function." Scientific World Journal 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/359621.

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Fibrinogen is one of the plasma proteins most susceptible to oxidative modification. It has been suggested that modification of fibrinogen may cause thrombotic/bleeding complications associated with many pathophysiological states of organism. We exposed fibrinogen molecules to three different modification reagents—malondialdehyde, sodium hypochlorite, and peroxynitrite—that are presented to various degrees in different stages of oxidative stress. We studied the changes in fibrin network formation and platelet interactions with modified fibrinogens under flow conditions. The fastest modificatio

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Kang, Z., H. Li, G. Li, and D. Yin. "Reaction of pyridoxamine with malondialdehyde: Mechanism of inhibition of formation of advanced lipoxidation end-products." Amino Acids 30, no. 1 (2005): 55–61. http://dx.doi.org/10.1007/s00726-005-0209-6.

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Hardiany, Novi Silvia, Sucitra Sucitra, and Reni Paramita. "Profile of malondialdehyde (MDA) and catalase specific activity in plasma of elderly woman." Health Science Journal of Indonesia 10, no. 2 (2020): 132–36. http://dx.doi.org/10.22435/hsji.v12i2.2239.

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Latar belakang: Malondialdehida (MDA) merupakan petanda stres oksidatif yang merupakan produk akhir dari reaksi berantai proksidasi lipid. Untuk mencegah stres oksidatif, tubuh mensintesis katalase, suatu enzim antioksidan endogen yang mengkatalisis hidrogen peroksida (H2O2) menjadi air dan oksigen. Sampai saat ini kadar MDA dan katalase pada populasi usia lanjut (usila) masih memberikan hasil yang bervariasi dan kadar tersebut pada kelompok usia yang berbeda dalam populasi usila belum pernah dilaporkan. Dengan demikian, penelitian ini bertujuan untuk menganalisis profil kadar MDA dan aktivita

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Yasin, Yade Kurnia, Martha Irene Kartasurya, and RA Kisdjamiatun RMD. "Pengaruh kombinasi vitamin c dan vitamin e terhadap Kadar malondialdehid plasma pasien diabetes mellitus tipe 2." Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) 4, no. 1 (2016): 1–8. http://dx.doi.org/10.14710/jgi.4.1.1-8.

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Background: Malondialdehyde (MDA) levels produced by oxidative stress in type 2 diabetes mellitus (T2DM) is higher than in non diabetes patients. Vitamin C and E inhibit oxidative stress and MDA production. The purpose of this study was to prove the effects of combined vitamin C and vitamin E on MDA plasma levels in T2DM patients.Methods: This double blind randomized pre post test control group design was carried out on 35 patients with T2DM without complication (age 40-60 yr) in Makassar. The treatment group (n=18) received vitamin C 250 mg/day plus vitamin E 400 IU/day and the control group

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Pilip, Larisa V., Olga V. Byakova, and Maria E. Kazakova. "Influence of parasitic invasions on the values of malondialdehyde and ceruloplasmin in horses." Butlerov Communications 63, no. 8 (2020): 105–9. http://dx.doi.org/10.37952/roi-jbc-01/20-63-8-105.

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Parasitic invasions in horses often cause metabolic disorders and have a negative impact on their health and performance. The purpose of this research was to study the processes of lipid peroxidation and antioxidant protection in horse helminthiases, as well as following the deworming with a drug containing the antioxidant santoquine. The intensity of lipid peroxidation and antioxidant protection was determined in horses with different degrees of invasion by concentrations of malondialdehyde and ceruloplasmin accumulated in the blood. The studies have revealed that the concentration of malondi

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Myazin, R. G., and D. N. Emel’yanov. "Features of therapy of alcoholic liver disease in persons of young age." Experimental and Clinical Gastroenterology 174, no. 2 (2020): 80–85. http://dx.doi.org/10.31146/1682-8658-ecg-174-2-80-85.

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The aim of this study was to study the eff ects of using the infusion drug Remaxol in young patients with alcoholic liver disease.Materials and methods: the clinical and laboratory data of 80 young patients with alcoholic liver disease were analyzed, divided depending on the treatment regimen into 2 groups: the main (n = 44) who received Remaxol according to the scheme: 400 ml iv, drip, at a rate 40–60 drops per minute daily, course No. 5–10, and control (n = 36) — received basic therapy. In all patients, the dynamics in blood serum was studied: lipid peroxidation indices (malondialdehyde, die

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Valle, Emanuela, Liviana Prola, Diana Vergnano, et al. "Investigation of hallmarks of carbonyl stress and formation of end products in feline chronic kidney disease as markers of uraemic toxins." Journal of Feline Medicine and Surgery 21, no. 6 (2018): 465–74. http://dx.doi.org/10.1177/1098612x18783858.

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Objectives Cats are commonly affected by chronic kidney disease (CKD). Many reactive carbonyl intermediates and end products originating from the oxidative stress pathways are recognised as uraemic toxins and may play a role in CKD progression. The aim of the present study is to confirm whether carbonyl end-product formation is higher in cats affected by CKD and to assess whether an angiotensin-converting enzyme inhibitor (ACEi) might affect these hallmarks. Methods Twenty-two cats were divided into three groups: a control group (CG), cats with CKD and cats with CKD treated with an ACEi. Serum

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Khosravi, Amir. "Effects of concurrent eight-week aerobic trainings and Rosa canina L. fruit hydroalcoholic extract on liver enzymes and malondialdehyde of liver in male rats following an acute aerobic exercise until exhaustion." Medical Journal of Tabriz University of Medical Sciences and Health Services 42, no. 6 (2021): 701–12. http://dx.doi.org/10.34172/mj.2021.011.

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Background: Rosa canina L. has high levels of carotenoids, flavonoids and, vitamin C antioxidant compounds that can withstand the destructive effects of exhaustive exercise-induced oxidative stress. The present study aims to investigate the effects of concurrent eight-week aerobic training and Rosa canina L. fruit hydroalcoholic extract on some liver enzymes and malondialdehyde of liver in male rats following an acute aerobic exercise until exhaustion. Methods: The present research was an experimental study. Forty male Wistar rats were randomly divided into four groups (N=10): placebo (without

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Pal, Swati, Sumit Sen, Indrajit Nath, Arun Kumar, and Utpal Kumar Biswas. "Psoriasis, An inflammatory condition associated with oxidative stress." Asian Journal of Medical Sciences 12, no. 4 (2021): 24–30. http://dx.doi.org/10.3126/ajms.v12i4.33343.

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Background: Psoriasis is a chronic inflammatory skin disease characterized by pathological skin lesions due to various exogenous and endogenous factors. Oxidative stress can be one of the causes for the occurrence of psoriasis as well as significant contributor to its progression. Skin exposure to a number of irritants or proinflammatory agents including UVA and UVB generates ROS through the oxidative burst in infiltrating leukocytes at the site of inflammation which damages the skin cells. Measurement of the oxidative stress marker like lipid peroxidation product Malondialdehyde (MDA) and Nit

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Aziz, N. M., M. Y. Kamel, and R. A. Rifaai. "Eff ects of hemin, a heme oxygenase-1 inducer in L-arginine-induced acute pancreatitis and associated lung injury in adult male albino rats." Endocrine Regulations 51, no. 1 (2017): 20–30. http://dx.doi.org/10.1515/enr-2017-0003.

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AbstractObjective. The aim of the current study was to assess the protective outcome of hemin, a heme oxygenase-1 (HO-1) inducer on L-arginine-induced acute pancreatitis in rats. Acute pancreatitis (AP) is considered to be a critical inflammatory disorder with a major impact on the patient health. Various theories have been recommended regarding the pathophysiology of AP and associated pulmonary complications.Methods. Twenty-four adult male albino rats were randomly divided into four groups: control group, acute pancreatitis (AP), hemin pre-treated AP group, and hemin post-treated AP group.Res

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Schutt, Florian, Marion Bergmann, Frank G. Holz, and Jurgen Kopitz. "Proteins Modified by Malondialdehyde, 4-Hydroxynonenal, or Advanced Glycation End Products in Lipofuscin of Human Retinal Pigment Epithelium." Investigative Opthalmology & Visual Science 44, no. 8 (2003): 3663. http://dx.doi.org/10.1167/iovs.03-0172.

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Cavassani, Sâmia Santos, Virginia Berlanga Campos Junqueira, Juliana Britto Moraes, et al. "Short courses of mechanical ventilation with high-O2 levels in elderly rat lungs." Acta Cirurgica Brasileira 26, no. 2 (2011): 107–13. http://dx.doi.org/10.1590/s0102-86502011000200006.

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PURPOSE: To evaluate the effects of mechanical ventilation (MV) of high-oxygen concentration in pulmonary dysfunction in adult and elderly rats. METHODS: Twenty-eight adult (A) and elderly (E), male rats were ventilated for 1 hour (G-AV1 and G-EV1) or for 3 hours (G-AV3 and G-EV3). A and E groups received a tidal volume of 7 mL/kg, a positive end-expiratory pressure of 5 cm H2O, respiratory rate of 70 cycles per minute, and an inspiratory fraction of oxygen of 1. We evaluated total protein content and malondialdehyde in bronchoalveolar lavages (BAL) and performed lung histomorphometrical analy

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Lavado, Guadalupe, Nieves Higuero, Manuel León-Camacho, and Ramón Cava. "Formation of Lipid and Protein Oxidation Products during In Vitro Gastrointestinal Digestion of Dry-Cured Loins with Different Contents of Nitrate/Nitrite Added." Foods 10, no. 8 (2021): 1748. http://dx.doi.org/10.3390/foods10081748.

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The effect of nitrate/nitrite (0, 37.5, 75, and 150 mg/kg) in the dry-cured loin formulation on the formation of lipid and protein oxidation products during in vitro digestion was evaluated. Dry-cured loins formulated with nitrate/nitrite resulted in significantly less lipid and protein oxidation than uncured loins before and after simulated digestion. Compared to loins added with 0 mg/kg nitrate/nitrite, dry-cured loins with 37.5, 75, and 150 mg/kg contained a significantly lower content of conjugated dienes, malondialdehyde, carbonyls, and non-heme iron, and higher amounts of nitrosylmioglob

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Islamiana, D., and M. Pramaningtyas. "Increased malondialdehyde (MDA) level in pancreas tissue of hyperlipidemic induced rats (Rattus norvegicus) by quail egg yolk (Coturnix coturnix)." Pancreatology 20 (November 2020): S84. http://dx.doi.org/10.1016/j.pan.2020.07.133.

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Islamiana, D., H. A. Sudiarto, and M. D. Pramaningtyas. "Malondialdehyde (MDA) level in cardiac tissue after induction of quail egg yolk (coturnix coturnix) in rats model (Rattus norvegicus)." Atherosclerosis 331 (August 2021): e131-e132. http://dx.doi.org/10.1016/j.atherosclerosis.2021.06.392.

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Ghadiri, Afsaneh, Fariba Mirzaei Bavil, Gholam Reza Hamidian, et al. "Can troxerutin pretreatment prevent testicular complications in prepubertal diabetic male rats?" Endocrine Regulations 54, no. 2 (2020): 85–95. http://dx.doi.org/10.2478/enr-2020-0011.

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AbstractObjective. The vast majority of type 1 diabetes leads to a higher prevalence of reproductive system’s impairments. Troxerutin has attracted much attention owing to its favorable properties, including antihyperglycemic, anti-inflammatory, and antiapoptotic effects. This investigation was proposed to evaluate whether pretreatment with troxerutin could prevent apoptosis-induced testicular disorders in prepubertal diabetic rats.Methods. Fifty prepubertal male Wistar rats were randomly allocated into five groups: control (C), troxerutin (TX), diabetic (D), diabetic+troxerutin (DTX), and dia

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Hedayati, M., S. Niazmand, M. Hosseini, Y. Baghcheghi, F. Beheshti, and S. Niazmand. "Vitamin E improved redox homeostasis in heart and aorta of hypothyroid rats." Endocrine Regulations 51, no. 4 (2017): 205–12. http://dx.doi.org/10.1515/enr-2017-0021.

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Abstract Objectives. The objective of this study was to evaluate the effect of vitamin E on the oxidative stress parameters and antioxidant defense enzymes in the heart and aorta of 6-n-propylthiouracil (PTU)-induced hypothyroid rats. Methods. The animals were divided into 4 experimental groups: Group 1 (Euthyroid) received tap water, Group 2 (Hypothyroid) received 0.05 % of PTU in dissolved in their drinking water, Group 3 (PTU+Vit E) hypothyroid rats treated with vitamin E, and Group 4 (Euthyroid+Vit E). Vitamin E was injected daily (20 mg/kg) to groups 3 and 4 via daily gavage for 6 weeks.

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Veissi, Masoud, Sima Jafarirad, Akram Ahangarpour, Seyede Marjan Mohaghegh, and Amal Saki Malehi. "Co-exposure to endocrine disruptors: effect of bisphenol A and soy extract on glucose homeostasis and related metabolic disorders in male mice." Endocrine Regulations 52, no. 2 (2018): 76–84. http://dx.doi.org/10.2478/enr-2018-0009.

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AbstractObjectives. Bisphenol A (BPA) is a xenoestrogen, which is commonly used as a monomer of polycarbonate plastics food containers and epoxy resins. Little is known about the interaction effects between xeno- and phyto- estrogens on glucose homeostasis or other metabolic disorders. The aim of this study was to examine effects of individual or combined exposure to low doses of BPA and soy extract on glucose metabolism in mice with the goal to establish its potential mechanisms.Methods. Fifty-four male mice were randomly divided into six groups. Mice were treated with soy extract at 60 or 15

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Ozan, E., MF Sonmez, S. Ozan, N. Colakoglu, S. Yilmaz, and T. Kuloglu. "Effects of melatonin and vitamin C on cigarette smoke–induced damage in the kidney." Toxicology and Industrial Health 23, no. 8 (2007): 479–85. http://dx.doi.org/10.1177/0748233708089023.

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This study was carried out to investigate smoke-induced structural and biochemical changes and protective effects of co-administered melatonin and vitamin C in the kidney. Twenty-four Wistar adult female rats were used in this study. Animals were divided into four groups. The first group rats were used as control. The second group of rats inhaled cigarette smoke. Smile smoke inhaling third and fourth group rats received melatonin and vitamin C, respectively. At the end of experimental study, kidney tissues and blood samples were taken under ether anesthesia. Tissues were prepared and examined

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Faizan, Mohammad, Ingunn Stubhaug, David Menoyo, et al. "Dietary Alpha-Tocopherol Affects Tissue Vitamin E and Malondialdehyde Levels but Does not Change Antioxidant Enzymes and Fatty Acid Composition in Farmed Atlantic Salmon (Salmo salar L.)." International Journal for Vitamin and Nutrition Research 83, no. 4 (2013): 238–45. http://dx.doi.org/10.1024/0300-9831/a000166.

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In this study the effect of increasing dietary alpha tocopherol on vitamin E tissue concentrations, lipid peroxidation (malondialdehyde), antioxidant enzymes, and fatty acid composition has been investigated in farmed Atlantic salmon. To this end fish (initial body weight ~ 193 g, n = 70 per group) were fed diets based on fish oil (27.5 %), fish meal (15.0 %), wheat gluten (20.6 %), and soy protein concentrate (24.0 %) for 14 weeks. Diets were supplemented with 0 (negative control), 150, and 400 mg/kg vitamin E as all-rac alpha-tocopheryl acetate. Dietary vitamin E did not affect feed conversi

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Estrada Cruz, Norma Angélica, Julio César Almanza Pérez, Ángeles Fortis Barrera, et al. "Acute Administration of Tibolone Prevents Oxidative Stress in Ovariectomized Rats Fed High-Fat-and-Fructose Diet." Experimental and Clinical Endocrinology & Diabetes 127, no. 06 (2018): 396–404. http://dx.doi.org/10.1055/a-0659-9928.

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AbstractIn addition to oxidative stress due to the increase of free radicals, estrogen deficiency is associated with changes in enzymatic activity, glutathione redox ratio (GSH/GSSG), and the content of oxidative markers such as malondialdehyde. Tibolone, a synthetic steroid, has been used as an elective treatment for the relief of menopausal symptoms. However, the acute effects of hormonal therapy with tibolone on metabolic parameters and oxidative stress markers associated with the first stages of estrogen deficiency are still unknown. The study aimed to evaluate if the acute administration

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Ozbasar, Demir, Ummuhan Toros, Okan Ozkaya, et al. "Raloxifene decreases serum malondialdehyde and nitric oxide levels in postmenopausal women with end-stage renal disease under chronic hemodialysis therapy." Journal of Obstetrics and Gynaecology Research 36, no. 1 (2010): 133–37. http://dx.doi.org/10.1111/j.1447-0756.2009.01086.x.

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Nazaimoon, WM Wan, and Khalid Bak. "Palm vitamin E reduced serum levels of glycated hemoglobin, advanced glycosylation end-products and malondialdehyde of STZ-induced diabetic rats." Diabetes Research and Clinical Practice 50 (September 2000): 357. http://dx.doi.org/10.1016/s0168-8227(00)81216-4.

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Morakinyo, Ayodele Olufemi, Titilola Aderonke Samuel, and Daniel Abiodun Adekunbi. "Magnesium upregulates insulin receptor and glucose transporter-4 in streptozotocin-nicotinamide-induced type-2 diabetic rats." Endocrine Regulations 52, no. 1 (2018): 6–16. http://dx.doi.org/10.2478/enr-2018-0002.

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Abstract Objective. We investigated the effects of magnesium supplementation on glucose tolerance, insulin sensitivity, oxidative stress as well as the concentration of insulin receptor and glucose transporter-4 in streptozotocin-nicotinamide induced type-2 diabetic (T2D) rats. Methods. Rats were divided into four groups designated as: 1) control (CTR); 2) diabetic untreated (DU); 3) diabetic treated with 1 mg of Mg/kg diet (Mg1-D); and 4) diabetic treated with 2 mg of Mg/kg diet (Mg2-D). T2D was induced with a single intraperitoneal (i.p.) injection of freshly prepared streptozotocin (55 mg/k

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Olukole, Samuel Gbadebo, Eunice Olufunke Ola-Davies, Damilare Olaniyi Lanipekun, and Bankole Olusiji Oke. "Chronic exposure of adult male Wistar rats to bisphenol A causes testicular oxidative stress: Role of gallic acid." Endocrine Regulations 54, no. 1 (2020): 14–21. http://dx.doi.org/10.2478/enr-2020-0003.

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AbstractObjectives. Bisphenol A (BPA) has been reported that among other male reproductive dys-functions, it can cause marked estrogenic effects including alteration in serum hormones as well as testicular lesions in exposed animals. This work sought to study the role of gallic acid (GA), a known antioxidant, on the BPA-induced testicular oxidative stress in adult male Wistar rats using serum hormone analysis, histopathology, and biochemical assays.Methods. Adult male rats were divided into four groups (n=10) including control (0.2 ml of corn oil), GA (20 mg/kg/day), BPA (10 mg/kg/day), BPA+GA

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Mohebbati, R., M. Hosseini, M. Haghshenas, A. Nazariborun, and Farimah Beheshti. "Th e eff ects of Nigella Sativa extract on renal tissue oxidative damage during neonatal and juvenile growth in propylthiouracil-induced hypothyroid rats." Endocrine Regulations 51, no. 2 (2017): 105–13. http://dx.doi.org/10.1515/enr-2017-0010.

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AbstractObjective. We investigated the effects of hydroalcoholic extract of Nigella sativa (NS) on renal tissue oxidative damage associated with propylthiouracil (PTU)-induced hypothyroidism during neonatal and juvenile growth in rats.Methods. Pregnant rats were divided into five groups designated as: 1) control; 2) propylthiouracil (PTU); 3) PTU-NS100; 4) PTU-NS200, and 5) PTU-NS400. All mothers except the control group received 0.005% PTU in their drinking water during lactation. Besides PTU, mothers in groups 3-5 received 100, 200, and 400 mg/kg of NS extract. After lactation period, the of

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Jokic, Aleksandar, Nikola Sremcevic, Zeki Karagülle, Tatjana Pekmezovic, and Vukosava Davidovic. "Oxidative stress, hemoglobin content, superoxide dismutase and catalase activity influenced by sulphur baths and mud packs in patients with osteoarthritis." Vojnosanitetski pregled 67, no. 7 (2010): 573–78. http://dx.doi.org/10.2298/vsp1007573j.

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Background/Aim. It is weel-known that sulphur baths and mud paks demonstrate beneficial effects on patients suffering from degenerative knee and hip osteoarthritis (OA) through the increased activity of protective antioxidant enzymes. The aim of this study was to assess lipid peroxidation level, i.e. malondialdehyde concetration, in individuals with knee and/or hip osteoarthritis (OA), as well as to determine the influence of sulphur baths and mud packs application on the activity of superoxide dismutase (SOD) and catalase (CAT) in order to minimize or eliminate excessive free radical species

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Boedi Setya Rahardja, Widy Ayunanti, Hari Suprapto,. "Pengaruh Pemberian Sari Kecambah Kacang Hijau terhadap Kadar Malondialdehid pada Ikan Lele Dumbo (Clarias gariepinus) yang Terinfeksi Bakteri Aeromonas hydrophila [Effect of Mung Bean Sprouts Essences against Malondialdehyde Levels In African catfish (Clarias gariepinus) Infected by Bacteria Aeromonas hydrophila ]." Jurnal Ilmiah Perikanan dan Kelautan 6, no. 2 (2019): 155. http://dx.doi.org/10.20473/jipk.v6i2.11302.

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Abstract African catfish (Clarias gariepinus) is a type of freshwater fish consumption with elongated body and smooth skin. Bacterial disease that often strikes African catfish and can cause death as well as a cause of primary infection is A.hydrophila. Bacterial infection may be one cause of the synthesis of lipid peroxidation which is an indication of the emergence of free radicals. And the end result of lipid peroxidation is malondialdehyde. Sprouts are the new little plants grow from seeds planted beans. Green bean seed germination will enrich vitamins including vitamin E, green beans or α

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Kuzina, Tatiana V., and Maya L. Galaktionova. "ANALYSIS OF THE INTERRELATION OF CYTOGENETIC HOMEOSTASIS AND OXIDATIVE STRESS IN THE ORGANISM OF GOBY FISH (GOBIIDAE) OF THE NORTHERN CASPIAN." South of Russia: ecology, development 13, no. 2 (2018): 64–72. http://dx.doi.org/10.18470/1992-1098-2018-2-64-72.

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Aim. The aim is to investigate the relationship between the content of micronuclei, destructive disorders in the nuclei of erythrocytes of peripheral blood of the goby fish and intensity of lipid peroxidation in fish tissues. Methods. Was used the method of quantitative accounting of morphologically altered red blood cells of peripheral blood of goby fish. Evaluation of cytogenetic disorders in fish blood cells was carried out based on a micronucleus test. Samples of muscle tissues and liver were sampled for biochemical analyzes. The rates of lipid peroxidation (LPO level) were determined by a

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Sadeghi, Fatemeh, Amirmansour Alavi-Naeini, Farahnaz Mardanian, Mohammad Reza Ghazvini, and Behzad Mahaki. "Omega-3 and vitamin E co-supplementation can improve antioxidant markers in obese/overweight women with polycystic ovary syndrome." International Journal for Vitamin and Nutrition Research 90, no. 5-6 (2020): 477–83. http://dx.doi.org/10.1024/0300-9831/a000588.

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Abstract. Background: Polycystic ovary syndrome is one of the most important factors in female infertility. Oxidative stress is likely to contribute to increased insulin and androgen production in the ovaries, as well as probably impairing follicle production. Aims: This study aims to determine the complementary effects of omega-3 and vitamin E supplements on certain oxidative stress indices in obese and overweight women with polycystic ovary syndrome. Materials and Methods: This double-blind, randomized clinical trial was performed on polycystic ovary syndrome subjects with BMI > 25. Patie

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Permatasari, Trinita Diyah, Rini Riyanti та Desie Dwi Wisudanti. "Hubungan antara Kadar Feritin dengan Malondialdehyde pada Pasien Talasemia β Mayor di RSD dr. Soebandi Jember". Pustaka Kesehatan 7, № 1 (2020): 52. http://dx.doi.org/10.19184/pk.v7i1.17592.

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Repeated blood transfusions, increased iron absorption, and ineffective erythropoiesis in major β thalassemia patients lead to iron overload characterized by elevated ferritin levels. Free iron will catalyze reactive oxygen species (ROS) formation by Fenton reaction that cause oxidative stress. Malondialdehyde (MDA) is the lipid peroxidation end product used to measure the oxidative stress. This study aimed to determine the correlation between ferritin levels and MDA levels in major β thalassemia patients at dr. Soebandi Hospital Jember. An analitic observational study with cross sectional stu

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Kirimi, E., O. Tuncer, M. Kösem, et al. "The Effects of Prednisolone and Serum Malondialdehyde Levels in Puppies with Experimentally Induced Meconium Aspiration Syndrome." Journal of International Medical Research 31, no. 2 (2003): 113–22. http://dx.doi.org/10.1177/147323000303100207.

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The aim of this study was to investigate the effect of different doses of prednisolone in puppies experimentally induced with meconium aspiration syndrome (MAS). Meconium was collected from human babies in the first day of life and was released into the trachea of 11 newborn puppies to induce MAS. Puppies were treated with 2 mg/kg prednisolone (standard dose), 30 mg/kg prednisolone (megadose) or 0.9% saline, all administered intravenously. The study ended 20 h after meconium aspiration and the lungs were then scored for histopathology. Animals not treated with prednisolone deteriorated after 8

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Sakuraba, K., A. Krishnamurthy, A. Circiumaru, et al. "POS0400 METABOLIC CHANGES INDUCED BY ANTI-MALONDIALDEHYDE/MALINDIALDEHYDE-ACETALDEHYDE ANTIBODIES PROMOTE OSTEOCLAST DEVELOPMENT." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 429. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3678.

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Background:Malondialdehyde (MDA) is a highly reactive compound generated during lipid-peroxidation in conditions associated with oxidative stress. MDA can irreversibly modify proteins (e.g. lysine, arginine and histidine residues). In addition, acetaldehyde can further react with MDA adducts to form malondialdehyde-acetaldehyde (MAA) modification. Such protein modifications can lead to immunogenic neo-epitopes that are recognized by autoantibodies. In fact, anti-MDA/MAA IgG antibodies are significantly increased in the serum of patients with autoimmune diseases, such as rheumatoid arthritis (R

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Wen, Gu, Tao, Cheng, Wang, and Zhou. "Effects of Ginger Extract on Laying Performance, Egg Quality, and Antioxidant Status of Laying Hens." Animals 9, no. 11 (2019): 857. http://dx.doi.org/10.3390/ani9110857.

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The objective of this study was to investigate the effects of ginger extract (GE) as a dietary supplement for laying hens. A total of 40-week-old 288 Hyline Brown laying hens were randomly divided into two groups with six replicates, and fed a basal diet with or without 100 g/t GE for eight weeks. Dietary GE supplementation increased egg weight, albumin height, and Haugh unit of eggs, and decreased yolk cholesterol content and activities of alanine transaminase and aspartate transaminase in serum at eight weeks. Moreover, GE resulted in higher total superoxide dismutase (T-SOD) activity and lo

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Alic, Lejla, Nikolina Papac-Milicevic, Darina Czamara, et al. "A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes." Proceedings of the National Academy of Sciences 117, no. 18 (2020): 9942–51. http://dx.doi.org/10.1073/pnas.1913970117.

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Genetic variants within complement factor H (CFH), a major alternative complement pathway regulator, are associated with the development of age-related macular degeneration (AMD) and other complementopathies. This is explained with the reduced binding of CFH or its splice variant factor H-like protein 1 (FHL-1) to self-ligands or altered self-ligands (e.g., malondialdehyde [MDA]-modified molecules) involved in homeostasis, thereby causing impaired complement regulation. Considering the critical role of CFH in inhibiting alternative pathway activation on MDA-modified surfaces, we performed an u

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Raphael, Jacob, Yaacov Gozal, Nachum Navot, and Zhiyi Zuo. "Activation of Adenosine Triphosphate–regulated Potassium Channels during Reperfusion Restores Isoflurane Postconditioning-induced Cardiac Protection in Acutely Hyperglycemic Rabbits." Anesthesiology 122, no. 6 (2015): 1299–311. http://dx.doi.org/10.1097/aln.0000000000000648.

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Abstract Background: Hyperglycemia is known to inhibit myocardial anesthetic postconditioning. The authors tested whether activation of adenosine triphosphate–regulated potassium (KATP) channels would restore anesthetic postconditioning during acute hyperglycemia. Methods: Rabbits subjected to 40-min myocardial ischemia and 3-h reperfusion (ischemia–reperfusion [I/R]) were assigned to groups (n = 10 in each group) with or without isoflurane postconditioning (2.1% for 5 min) in the presence or absence of hyperglycemia and/or the KATP channel agonist diazoxide. Creatine kinase MB fraction and in

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Özkan-Yılmaz, Ferbal, Arzu Özlüer-Hunt, and Mehmet Berköz. "Mannan oligosakkarit (MOS) İlaveli Yemlerle Beslenen Oreochromis niloticus’un Karaciğer Paraoksonaz Enzim Aktivitesi ve Malondialdehit Düzeyinin Araştırılması." Turkish Journal of Agriculture - Food Science and Technology 3, no. 8 (2015): 639. http://dx.doi.org/10.24925/turjaf.v3i8.639-643.413.

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In this study, it was evaluated paraoxonase activity (PON) and malondialdehyde (MDA) level in liver tissue of Oreochromis niloticus fed with mannan oligosaccharide (MOS) supplemented diet. For this purpose, fish were fed commercial diet supplemented with 0.25%, 0.35% and 0.45% dietary MOS for 60 days. At the end of experiment, PON activity of liver tissue was increased in MOS groups when compared to control group. It was determined that MDA level of tissue was decreased significantly in MOS groups when compared to control group.

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Ahmadi-Motamayel, Fatemeh, Seyede Sareh Hendi, and Mohammad Taghi Goodarzi. "Evaluation of Salivary Lipid Peroxidation End Product Level in Dental Caries." Infectious Disorders - Drug Targets 20, no. 1 (2020): 65–68. http://dx.doi.org/10.2174/1871526519666181123182120.

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Background: Tissue destruction can be measured by the level of lipid peroxidation (LP) end products. Since free radicals are very reactive with low survival time, the level of free radicals and oxidative stress activity are measured indirectly by tissue damage end product assessment, i.e. Malondialdehyde (MDA) that is a final end product of LP. Objective: The aim of this study was to evaluate salivary MDA level as an indicator of oxidative stress; in caries-active and caries-free students. Methods: total of 100 male and female students, 15-17 years of age, participated in this casecontrol stud

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Dries, Samuel Selbach, Bárbara Da Silveira Soares, Ana Luiza Ziulkoski, et al. "Oxidative stress in patients with type 2 diabetes mellitus treated with metformin." Scientia Medica 27, no. 2 (2017): 25857. http://dx.doi.org/10.15448/1980-6108.2017.2.25857.

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*** Oxidative stress in patients with type 2 diabetes mellitus treated with metformin ***AIMS: To evaluate oxidative stress parameters in patients with type 2 diabetes mellitus treated with metformin, relating these values to its side effects, plasma levels, glycemic control, diabetic complications, lipid profile, and the influence of pharmacotherapeutic follow-up.METHODS: Patients with type 2 diabetes mellitus, on metformin and in pharmacotherapeutic follow-up for four months, were evaluated. The pharmacotherapeutic follow-up consisted in providing information and answering patients’ question

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Tejada, Silvia, and Antoni Sureda. "A new approach using biomarkers to elucidate the regression state of the invasive alga Caulerpa taxifolia in waters around the Balearic Islands (Western Mediterranean Sea)." Marine and Freshwater Research 64, no. 10 (2013): 986. http://dx.doi.org/10.1071/mf13012.

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Invasive algae alter the structure and function of ecosystems. The green alga Caulerpa taxifolia is an invasive alga introduced in the Mediterranean Sea, whereas Caulerpa prolifera is a native species in Mediterranean waters. The aim of the current work was to determine the oxidative status of both Caulerpa species by means of biomarker measures as a possible indicator of the regression state of C. taxifolia in waters around the Balearic Islands (western Mediterranean Sea). The levels of markers of lipid peroxidation, glutathione concentration, activities of antioxidant enzymes and caulerpenyn

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Sibiya, Samukelisiwe, Bonisiwe Msibi, Andile Khathi, Ntethelelo Sibiya, Irvin Booysen, and Phikelelani Ngubane. "The effect of dioxidovanadium complex (V) on hepatic function in streptozotocin-induced diabetic rats." Canadian Journal of Physiology and Pharmacology 97, no. 12 (2019): 1169–75. http://dx.doi.org/10.1139/cjpp-2019-0369.

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Diabetics are susceptible to hepatic dysfunction risks due to hyperglycaemia and insulin therapy. Conventional diabetes treatments improve glycaemic control; however, hepatic hazards associated with these agents remains a challenge. Accordingly, this study sought to investigate the effect of a dioxidovanadium complex (V) on the hepatic function in streptozotocin-induced diabetic rats. Sprague-Dawley rats (240–250 g) were divided into 4 groups (n = 6): nondiabetic control, diabetic control, insulin-treated, and vanadium complex groups. The dioxidovanadium (10, 20, and 40 mg/kg) was administered

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