Relevant bibliographies by topics / Malonic acid derivative

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Academic literature on the topic 'Malonic acid derivative'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Malonic acid derivative"

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Xavier, Tania, Sylvie Condon, Christophe Pichon, Erwan Le Gall, and Marc Presset. "Preparation of mono-substituted malonic acid half oxyesters (SMAHOs)." Beilstein Journal of Organic Chemistry 17 (August 18, 2021): 2085–94. http://dx.doi.org/10.3762/bjoc.17.135.

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The use of mono-substituted malonic acid half oxyesters (SMAHOs) has been hampered by the sporadic references describing their preparation. An evaluation of different approaches has been achieved, allowing to define the best strategies to introduce diversity on both the malonic position and the ester function. A classical alkylation step of a malonate by an alkyl halide followed by a monosaponification gave access to reagents bearing different substituents at the malonic position, including functionalized derivatives. On the other hand, the development of a monoesterification step of a substit
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Berhow, Mark A., Raymond D. Bennett, Katherine Kanes, Stephen M. Poling, and Carl E. Vandercook. "A malonic acid ester derivative of naringin in grapefruit." Phytochemistry 30, no. 12 (1991): 4198–200. http://dx.doi.org/10.1016/0031-9422(91)83505-f.

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3

Grishina, A. Yu, D. Yu Ivkin, S. M. Napalkova, and O. V. Buyuklinskaya. "Quality Assurance System when Studying the Pharmacological Safety of Etmaben." Journal Biomed 20, no. 3 (2024): 71–74. http://dx.doi.org/10.33647/2074-5982-20-3-71-74.

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Quality assurance plays a key role in preclinical research, where every detail must be strictly controlled and verified. Standard operating procedures are essential part of any quality assurance system, defining precisely the steps and methods of implementing certain tasks or processes in a laboratory. In this article, the main components of a quality assurance system are discussed using the example of studying the pharmacological safety of a malonic acid derivative.
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Ivkin, D. Yu, M. V. Krasnova, E. D. Semivelichenko, A. A. Karpov, V. E. Kovanskov, and S. V. Okovitiy. "Comparative Efficacy of Etmaben and Empagliflozin in Mono- and Combined Therapy of Experimental Chronic Heart Failure." Journal Biomed 20, no. 3E (2024): 187–90. http://dx.doi.org/10.33647/2713-0428-20-3e-187-190.

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The cardiotropic activity of etmaben, a malonic acid derivative, has been confirmed by a number of studies. The possibility of using empagliflozin in chronic heart failure has been proven in a number of preclinical and clinical studies. In this study, the efficacy of the drugs in monotherapy and combined use regimens is compared using a model of experimental chronic heart failure in rats. The most effective treatment regimen was found to be etmaben; its combination with empagliflozin led to a decrease in effectiveness, regardless of which of these drugs was the starting drug.
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Yang, Xinlin, Lin Chen, Xinge Qiao, and Cuihong Fan. "Photo-Induced Damages of Cytoplasmic and Mitochondrial Membranes by a [C60]Fullerene Malonic Acid Derivative." International Journal of Toxicology 26, no. 3 (2007): 197–201. http://dx.doi.org/10.1080/10915810701352606.

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The biological activities of fullerene derivatives have attracted much attention in the last decade. In this paper, effects of dimalonic acid C60 (DMA C60) on cytoplasmic membrane, intracellular calcium concentration ([Ca2+]i), and mitochondrial membrane in HeLa cells were studied by using laser scanning confocal microscopy together with fluorescent probes propidium iodide (PI), fluo-3 acetoxymethyl ester (fluo-3 AM), and tetramethyl rhodamine methyl ester (TMRM). The data showed that under laser irradiation produced by a Kr/Ar laser source with a low power less than 1 mW, DMA C60 might induce
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Tsao, Nina, Puthuparampil P. Kanakamma, Tien-Yau Luh, Chen-Kung Chou, and Huan-Yao Lei. "Inhibition of Escherichia coli-Induced Meningitis by Carboxyfullerence." Antimicrobial Agents and Chemotherapy 43, no. 9 (1999): 2273–77. http://dx.doi.org/10.1128/aac.43.9.2273.

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ABSTRACT The effect of a water-soluble malonic acid derivative of carboxyfullerence (C60) against Escherichia coli-induced meningitis was tested. C60 can protect the mice from E. coli-induced death in a dose-dependent manner. C60 administered intraperitoneally as late as 9 h after E. coliinjection was still protective. The C60-treated mice had less tumor necrosis factor alpha and interleukin-1β production by staining of brain tissue compared to the levels of production for nontreated mice. The E. coli-induced increases in blood-brain barrier permeability and inflammatory neutrophilic infiltrat
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Diaz-Ballote, Luis, Luis Maldonado-Lopez, Liliana San-Pedro, Emanuel Hernández-Nuñez, and Juan Genesca. "Glycerol and malonic acid as corrosion inhibitors seen through the density functional theory perspective." Journal of the Serbian Chemical Society, no. 00 (2022): 12. http://dx.doi.org/10.2298/jsc211201012d.

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Glycerol (G) is the major co-product in the transesterification process of biodiesel. As clean energy demand increases, the production of G also increases and new ways of re-using it are needed. In the last decade, some experimental studies claimed that G and its derivative, malonic acid (MA), could be used as corrosion inhibitors. Yet, presently, there is little evidence of it and more studies are needed to confirm that G and MA could have a good performance in metal protection. The present work aims to study the reactivity of G and MA, since reactivity and inhibition are intimately linked. T
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Valenta, Vladimír, Zdeněk Vejdělek, Karel Šindelář, and Miroslav Protiva. "Potential anticonvulsants: Some derivatives and analogues of 2-propylpentanoic acid." Collection of Czechoslovak Chemical Communications 55, no. 4 (1990): 1067–76. http://dx.doi.org/10.1135/cccc19901067.

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Reaction of 2-(ethoxycarbonylamino)ethanol with 2-propylpentanoyl chloride gave the ester III. N-(4-Piperidinyl)-2-propylpentanamide (V) was prepared via the 1-benzyl-4-piperidinyl derivative IV and was acylated with ethanesulfonyl chloride and 2-propylpentanoyl chloride to give the amides VI and VII. Malonic ester syntheses afforded diethyl 2-ethyl- and 2-propyl-2-(2-(methylthio)ethyl)malonate VIII and XIII which were hydrolyzed and decarboxylated to the acids X and XV which, in turn, were transformed to the amides XII and XVII. 3-Thiapentanenitrile was alkylated with propyl bromide to the ni
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Miyazawa, Kun'ichi, Tadahiko Mashino, and Tadatomo Suga. "Structural characterization of the C60[C(COOC2H5)2] whiskers prepared by the liquid–liquid interfacial precipitation method." Journal of Materials Research 18, no. 11 (2003): 2730–35. http://dx.doi.org/10.1557/jmr.2003.0380.

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Fine whiskers of a C60 derivative, i.e., C60 monosubstituted by ethyl ester of malonic acid, C60[C(COOC2H5)2], were fabricated for the first time using a system of toluene with concentrated C60[C(COOC2H5)2] and isopropyl alcohol. The center-to-center distance of C60[C(COOC2H5)2] molecules along the close-packed direction of the C60[C(COOC2H5)2] whiskers was in the same range as that of the C60 nanowhiskers prepared by the same method. The C60[C(COOC2H5)2] whiskers were assumed to take body-centered tetragonal or hexagonal close-packed crystal structures. The C60[C(COOC2H5)2] whiskers showed a
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Werfeli, Ali, Jan Čejka, Ondřej Klecán, Bohumil Kratochvíl, and Josef Kuthan. "Preparation of New Optically Active Furanoids Containing Various Aza-Heterocyclic Moieties." Collection of Czechoslovak Chemical Communications 62, no. 6 (1997): 894–912. http://dx.doi.org/10.1135/cccc19970894.

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The aldehyde 2 prepared from [5-(2,3-O-isopropylidene-β-D-erythrofuranosyl)-2-methylfuran-3-yl]methanol (1) was converted to E,Z-oximes 3, 4 and imine derivative 5 by the reaction with hydroxylamine and pyridin-2-yl amine, respectively. The Knoevenagel reaction with malonic acid afforded exclusively the 3-substituted acrylic acid 6 while corresponding Hantzsch 1,4-dihydropyridines 7 and 8 were obtained by the reaction of aldehyde 2 with ethyl acetoacetate or acetylacetone and ammonia. 3,5-Dicyano-1,4-dihydropyridine derivative 9 was isolated only in forms of hydrates after the reaction of alde
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Dissertations / Theses on the topic "Malonic acid derivative"

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Nien, Chih-Ying, and 粘知盈. "Synthesis of Bis-(di-acetic acid) and Bis-malonic Acid Sodium Salt Derivatives as Potential Metal Chelators." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/58828990691580343400.

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碩士<br>國防醫學院<br>藥學研究所<br>94<br>Metal ions are essential cofactors for many functional metalloproteins. Thus, removel of metal ions may be a useful way to alter the function of metalloproteins. Metal ions chelators are a class of chemical agents that are able not only to bind and remove metal ions from the body, even from metalloproteins. In the past decade, many new viable utilities for metal ions chelators have been reported. This includes the use of iron chelators as antiviral, antiproliferative, antifibrotic, and photoprotective. EDTA has been shown to be a powerful chelators, which chelates
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Lin, Chih-Chen, and 林志成. "Susceptibility and physics of Staphylococcus aureus was treated with 2-(10-hydroxydecyl)malonic acid and derivatives." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/22595445338542484361.

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碩士<br>淡江大學<br>生命科學研究所碩士班<br>93<br>The differences of structural conformation and surface force on Staphylococcus aureus-ATCC 25923(S. aureus-25923) was treated with 2-(10-hydroxydecyl)malonic acid and were measured by atomic force microscope technology. Susceptibility to 2-(10-hydroxydecyl)malonic acid concentration was investigated with the population analysis technique in reference strains of S. aureus-25923. Comparisons of these results showed that S. aureus-25923 were inhibited by 2-(10-hydroxydecyl)malonic acid which concentration was approximately equal or higher than 100 ppm of the res
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Yu, Hui-Chen, and 余蕙甄. "Synthesized of transition metal coordination polymers by using malonic acid derivatives and bipyridinely ligands：structural and magnetical characterizations." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/85802448183015523579.

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碩士<br>東海大學<br>化學系<br>101<br>This research is focus on the synthesis of transition metal coordination polymers (Mn, Co, Ni) based on the malonic acid derivatives Dimethylmalonic acid (H2-Me2mal), and Diethylmalonic acid (H2-Et2mal), and 4,4′-Bipyridine (bpy) and 1,2-Di(4-pyridyl)ethylene (dpe). The compounds {[Mn(Me2mal)(bpy)0.5(H2O)]}n (1), {[Co(Me2mal)(bpy)0.5(H2O)]}n (2), {[Ni(Me2mal)(bpy)0.5(H2O)]}n (3), {[Mn(H-Et2mal)2(bpy)(H2O)2]}n (4), {[Co2(Et2mal)2(bpy)2(H2O)2]•2H2O•2DMF}n (5), {[Ni2(Et2mal)2(bpy)2(H2O)2]•2H2O•2DMF}n (6), {[Co(Me2mal)(dpe)0.5(H2O)]}n (7), and {[Co2(Me2mal)2(dpe)]}n (8)
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Books on the topic "Malonic acid derivative"

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Zürich, Eidgenössische Technische Hochschule, ed. The development of new magnesium ion-selective electrodes based on malonic acid diamide derivatives. 1995.

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Book chapters on the topic "Malonic acid derivative"

1

Mack, H. G. "Gas-Phase Structures and Conformational Properties of Malonic Acid Derivatives, [CY2(COX)2], as Studied by Electron Diffraction and Ab Initio Calculations." In Structures and Conformations of Non-Rigid Molecules. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2074-6_26.

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"α-Substitution Reactions in Carboxylic Acids and Derivatives." In The Chemistry of Carbonyl Compounds and Derivatives. The Royal Society of Chemistry, 2022. http://dx.doi.org/10.1039/9781837670888-00381.

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The chemistry of carboxylic acid derivatives containing at least one hydrogen α to the carbonyl group is the focus of this chapter. The synthesis of β-ketoesters by the Claisen condensation illustrates the enolization and condensation processes guided by the pKa difference between the nucleophile and the product. The importance of malonic and acetoacetic esters for the preparation of carboxylic acids and derivatives (malonic ester synthesis) and ketones (acetoacetic ester synthesis) is presented. The biosynthetic relevance of the Claisen and Dieckmann condensations in the metabolism and the sy
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Austin, W. F., J. J. Kowalczyk, G. B. Dudley, and R. L. Danheiser. "Elimination from Malonic Acid Derivatives." In Three Carbon-Heteroatom Bonds: Thio-, Seleno-, and Tellurocarboxylic Acids and Derivatives; Imidic Acids and Derivatives; Ortho Acid Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-023-00205.

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Kollenz, G., and S. Ebner. "Of (Trifluoromethyl)malonic Acid Derivatives." In Three Carbon-Heteroatom Bonds: Thio-, Seleno-, and Tellurocarboxylic Acids and Derivatives; Imidic Acids and Derivatives; Ortho Acid Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-023-00326.

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Masse, C. E. "Malonic Acids by Acylation of Acetic Acid Derivatives." In Three Carbon-Heteroatom Bonds: Acid Halides; Carboxylic Acids and Acid Salts. Georg Thieme Verlag KG, 2007. http://dx.doi.org/10.1055/sos-sd-020-00292.

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Austin, W. F., J. J. Kowalczyk, G. B. Dudley, and R. L. Danheiser. "Reaction with Nucleophiles Leading to Malonic Acid Derivatives." In Three Carbon-Heteroatom Bonds: Thio-, Seleno-, and Tellurocarboxylic Acids and Derivatives; Imidic Acids and Derivatives; Ortho Acid Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-023-00209.

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7

Tidwell, T. T. "Alkyl(aryl)ketenes by Decarboxylation of Malonic Acids." In Three Carbon-Heteroatom Bonds: Thio-, Seleno-, and Tellurocarboxylic Acids and Derivatives; Imidic Acids and Derivatives; Ortho Acid Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-023-00430.

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Kollenz, G., and S. Ebner. "Dehydrochlorination of Malonyl Chlorides." In Three Carbon-Heteroatom Bonds: Thio-, Seleno-, and Tellurocarboxylic Acids and Derivatives; Imidic Acids and Derivatives; Ortho Acid Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-023-00319.

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Stanovnik, B., and J. Svete. "From Malonic Acid Derivatives and Hydrazines." In Five-Membered Hetarenes with Two Nitrogen or Phosphorus Atoms. Georg Thieme Verlag KG, 2002. http://dx.doi.org/10.1055/sos-sd-012-00031.

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Stanovnik, B., and J. Svete. "From Malonic Acid Derivatives and Arylhydrazines." In Five-Membered Hetarenes with Two Nitrogen or Phosphorus Atoms. Georg Thieme Verlag KG, 2002. http://dx.doi.org/10.1055/sos-sd-012-00032.

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