Academic literature on the topic 'Mammalian genomics'

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Journal articles on the topic "Mammalian genomics"

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Wayne, R. K., and E. A. Ostrander. "Mammalian genomics:." Heredity 92, no. 4 (2004): 273–74. http://dx.doi.org/10.1038/sj.hdy.6800428.

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O'Brien, S. J. "GENOMICS: On Choosing Mammalian Genomes for Sequencing." Science 292, no. 5525 (2001): 2264–66. http://dx.doi.org/10.1126/science.1059393.

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Jones, N. C., and P. A. Pevzner. "Comparative genomics reveals unusually long motifs in mammalian genomes." Bioinformatics 22, no. 14 (2006): e236-e242. http://dx.doi.org/10.1093/bioinformatics/btl265.

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Wuest, Diane M., Sarah W. Harcum, and Kelvin H. Lee. "Genomics in mammalian cell culture bioprocessing." Biotechnology Advances 30, no. 3 (2012): 629–38. http://dx.doi.org/10.1016/j.biotechadv.2011.10.010.

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Smith, Bria S., Geesa V. Daluwatumulle, Leslie A. Smith, James A. Cahill, and Kiley Graim. "Abstract 5042: The Paipu pipeline for pan-mammalian cancer genomics." Cancer Research 85, no. 8_Supplement_1 (2025): 5042. https://doi.org/10.1158/1538-7445.am2025-5042.

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Abstract The emerging field of comparative oncology may provide a novel solution to rare human cancer studies, as genomic resources, reference genomes, and non-human model cancer sequencing data are proliferating rapidly. Studying cancer across a diverse array of species provides a unique opportunity to interrogate factors underpinning cancer, facilitating disease modeling in the setting of spontaneous tumors complicated by comorbidities and metastases. Unfortunately, spontaneously developed tumors in non-human mammalian models have been largely overlooked, leaving a foundational resource unde
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Rodriguez-Osorio, Nelida, Hongfeng Wang, Jennifer Rupinski, Susan M. Bridges, and Erdogan Memili. "Comparative functional genomics of mammalian DNA methyltransferases." Reproductive BioMedicine Online 20, no. 2 (2010): 243–55. http://dx.doi.org/10.1016/j.rbmo.2009.11.006.

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Holmes, Roger S., Laura A. Cox, and John L. VandeBerg. "Mammalian carboxylesterase 3: comparative genomics and proteomics." Genetica 138, no. 7 (2010): 695–708. http://dx.doi.org/10.1007/s10709-010-9438-z.

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Holmes, Roger S., Laura A. Cox, and John L. VandeBerg. "Mammalian carboxylesterase 5: Comparative biochemistry and genomics." Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 3, no. 3 (2008): 195–204. http://dx.doi.org/10.1016/j.cbd.2008.05.002.

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Li, W. H., J. Nadeau, E. Ostrander, B. Van Valkenburgh, and P. Waddell. "Comparative Genomics: Mammalian Radiations -- Genome Maps 10." Science 286, no. 5439 (1999): 463–78. http://dx.doi.org/10.1126/science.286.5439.463.

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Hochgeschwender, Ute, and Miles B. Brennan. "The impact of genomics on mammalian neurobiology." BioEssays 21, no. 2 (1999): 157–63. http://dx.doi.org/10.1002/(sici)1521-1878(199902)21:2<157::aid-bies9>3.0.co;2-0.

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Dissertations / Theses on the topic "Mammalian genomics"

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Mikkelsen, Tarjei Sigurd 1978. "Mammalian comparative genomics and epigenomics." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/52808.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2009.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student submitted PDF version of thesis.<br>Includes bibliographical references.<br>The human genome sequence can be thought of as an instruction manual for our species, written and rewritten over more than a billion of years of evolution. Taking a complete inventory of our genome, dissecting its genes and their functional components, and elucidating
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Kiritsy, Michael C. "Functional Genomics of Mammalian Innate Immunity." eScholarship@UMMS, 2020. https://escholarship.umassmed.edu/gsbs_diss/1102.

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The breadth of genetic diversity in the mammalian immune response stands out amongst the ubiquity of variation seen in the genome, evidence that microbial infections have been a major driver of evolution. As technology has facilitated an understanding of the etiology of immunological diversity, so too has it enabled the assessment of its varied functions. Functional genomics, with its ability to assess both cause and effect, has revolutionized our understanding of fundamental biological phenomena and recalibrated our hypotheses. We build upon the model of host immunity established by rare gene
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Villanueva, Cañas José Luis 1984. "Insights into mammalian adaptive evolution through genomics data." Doctoral thesis, Universitat Pompeu Fabra, 2015. http://hdl.handle.net/10803/397756.

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Although the genome sequencing revolution is still in its infancy, we must acknowledge it as the major driver of biology since the beginning of the 21st century. The availability of a large collection of complete mammalian genomes due to high-throughput sequencing technologies allows us to begin the exploration of how the evolutionary diversification of gene content reflects the ecological adaptations of different taxa. Novelty arises in evolution through the transformation or combination of existing systems and, as shown recently, also from scratch. This thesis is centered around these differ
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Cheung, Hiu Tung (Tom). "Understanding mammalian transcriptional regulation using comparative and functional genomics." Diss., Connect to online resource, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3207751.

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Jordan, Gregory. "Analysis of alignment error and sitewise constraint in mammalian comparative genomics." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610693.

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Ratcliffe, Sarah. "Identification of a silicon-responsive gene in the mammalian genome." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610011.

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Siepel, Adam C. "Comparative mammalian genomics : models of evolution and detection of functional elements /." Diss., Digital Dissertations Database. Restricted to UC campuses, 2005. http://uclibs.org/PID/11984.

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Hsiao, Albert. "Comparative functional genomics of energy metabolism and insulin resistance in mammalian systems." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2005. http://wwwlib.umi.com/cr/ucsd/fullcit?p3165076.

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Thesis (Ph.D.)--University of California, San Diego, 2005.<br>Title from p. 1 of PDF file (viewed October 21, 2005) Vita. Includes bibliographical references (p. 170-175 ). Available online via UMI ProQuest Digital Dissertations.
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Saini, Harleen. "Intron and Small RNA Localization in Mammalian Neurons." eScholarship@UMMS, 2019. https://escholarship.umassmed.edu/gsbs_diss/1044.

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RNA molecules are diverse in form and function. They include messenger RNAs (mRNAs) that are templates for proteins, splice products such as introns that can generate functional noncoding RNAs, and a slew of smaller RNAs such as transfer RNAs (tRNAs) that help decode mRNAs into proteins. RNAs can show distinct patterns of subcellular localization that play an important role in protein localization. However, RNA distribution in cells is incompletely understood, with prior studies focusing primarily on RNAs that are long (>200 nucleotides), fully processed, and polyadenylated. We examined the di
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Endo, Yoshinori. "Comparative study of mammalian evolution by genomic analyses and pluripotent stem cell technology." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263514.

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Books on the topic "Mammalian genomics"

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Ruvinsky, A., and J. A. Marshall Graves, eds. Mammalian genomics. CABI, 2005. http://dx.doi.org/10.1079/9780851999104.0000.

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Organisation for Economic Co-operation and Development., ed. Mammalian embryo genomics. Organisation for Economic Co-operation and Development, 2003.

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Hu, Wei Shou, and An-Ping Zeng, eds. Genomics and Systems Biology of Mammalian Cell Culture. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-28350-5.

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An-Ping, Zeng, and SpringerLink (Online service), eds. Genomics and Systems Biology of Mammalian Cell Culture. 2nd ed. Springer Berlin Heidelberg, 2012.

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Genomics Workshop Identification of Functional Elements in Mammalian Genomes (2004 Cold Spring Harbor Laboratory). Abstracts of papers presented at the 2004 Genomics Workshop Identification of Functional Elements in Mammalian Genomes: November 11-November 13, 2004. Cold Spring Harbor Laboratory, 2004.

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Manocha, Marcus M. S. Isolation and characterization of genomic DNA sequences that enhance the stability of plasmid DNA in mammalian cells. Brock University, Centre for Biotechnology, 2005.

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Mammalian Embryo Genomics. OECD, 2003. http://dx.doi.org/10.1787/9789264104273-en.

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(Editor), A. Ruvinsky, and J. A. Marshall Graves (Editor), eds. Mammalian Genomics (Cabi Publishing). CABI, 2005.

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Organisation for economic co-operation and development. Mammalian Embryo Genomics (Biological Resource Management in Agriculture). OECD, 2003.

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Zeng, An-Ping, and Wei Shou Hu. Genomics and Systems Biology of Mammalian Cell Culture. Springer, 2014.

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Book chapters on the topic "Mammalian genomics"

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Recillas-Targa, Félix, Georgina Guerrero, Martín Escamilla-del-Arenal, and Héctor Rincón-Arano. "Gene Expression in Mammalian Cells." In Genomics. John Wiley & Sons, Ltd, 2010. http://dx.doi.org/10.1002/9780470711675.ch7.

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Goodstadt, Leo, and Chris P. Ponting. "Mammalian Genes and Evolutionary Genomics." In The Proteomics Protocols Handbook. Humana Press, 2005. http://dx.doi.org/10.1385/1-59259-890-0:543.

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Alekseyev, Max A., and Pavel A. Pevzner. "Limited Lifespan of Fragile Regions in Mammalian Evolution." In Comparative Genomics. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-16181-0_17.

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Wienberg, J., L. Frönicke, and R. Stanyon. "Insights into Mammalian Genome Organization and Evolution by Molecular Cytogenetics." In Comparative Genomics. Springer US, 2000. http://dx.doi.org/10.1007/978-1-4615-4657-3_8.

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Delbridge, Margaret L. "Gene Content of the Mammalian X Chromosome." In Marsupial Genetics and Genomics. Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9023-2_9.

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Ryvkin, Paul, Jin Jun, Edward Hemphill, and Craig Nelson. "Duplication Mechanism and Disruptions in Flanking Regions Influence the Fate of Mammalian Gene Duplicates." In Comparative Genomics. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-87989-3_3.

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Banerjee, Nilanjana, and Andrea Califano. "Transcription Factor Centric Discovery of Regulatory Elements in Mammalian Genomes Using Alignment-Independent Conservation Maps." In Comparative Genomics. Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11864127_16.

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Jun, Jin, Paul Ryvkin, Edward Hemphill, Ion Măndoiu, and Craig Nelson. "Estimating the Relative Contributions of New Genes from Retrotransposition and Segmental Duplication Events during Mammalian Evolution." In Comparative Genomics. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-87989-3_4.

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Matsuzawa, Shu-ichi, and John C. Reed. "Yeast and Mammalian Two-Hybrid Systems for Studying Protein-Protein Interactions." In Cancer Genomics and Proteomics. Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-335-6_14.

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Al Nadaf, Shafagh, Paul D. Waters, Janine E. Deakin, and Jennifer A. Marshall Graves. "Marsupial Genetics Reveals Insights into Evolution of Mammalian X Chromosome Inactivation." In Marsupial Genetics and Genomics. Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9023-2_13.

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Conference papers on the topic "Mammalian genomics"

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Bhatkar, Anup, and J. L. Rana. "Notice of Violation of IEEE Publication Principles - Estimating neutral divergence amongst Mammals for Comparative Genomics with Mammalian scope." In 2006 9th International Conference on Information Technology. IEEE, 2006. http://dx.doi.org/10.1109/icit.2006.52.

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Faryabi, Babak, Golnaz Vahedi, Jean-Francois Chamberland, Aniruddha Datta, and Edward R. Dougherty. "Constrained intervention in a cancerous mammalian cell cycle network." In 2008 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS). IEEE, 2008. http://dx.doi.org/10.1109/gensips.2008.4555669.

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Haussler, David. "Computational analysis of the human and other mammalian genomes." In the seventh annual international conference. ACM Press, 2003. http://dx.doi.org/10.1145/640075.640093.

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Tsang, Hiu-Gwen, Emily L. Clark, Stephen J. Bush, et al. "8 Generating a genomic-wide transcriptomic atlas of the mammalian cardiovascular system." In 20th Scottish Cardiovascular, Forum Abstracts, February 4th 2017, University of Glasgow, UK. BMJ Publishing Group Ltd and British Cardiovascular Society, 1997. http://dx.doi.org/10.1136/heartjnl-2017-311433.8.

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Vanoli, Fabio, Shuhei Ito, Richard L. Frock, Frederick W. Alt, Mary Ellen Moynahan, and Maria Jasin. "Abstract B37: PARP inhibitor olaparib induces genomic instability in normal mammalian cells." In Abstracts: AACR Special Conference on DNA Repair: Tumor Development and Therapeutic Response; November 2-5, 2016; Montreal, QC, Canada. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1557-3125.dnarepair16-b37.

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Li, G., S. S. Nair, S. J. Lees, and F. W. Booth. "Regulation of G2/M Transition in Mammalian Cells by Oxidative Stress." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-82349.

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The regulation of the G2/M transition for the mammalian cell cycle has been modeled using 19 states to investigate the G2 checkpoint dynamics in response to oxidative stress. A detailed network model of G2/M regulation is presented and then a “core” subsystem is extracted from the full network. An existing model of Mitosis control is extended by adding two important pathways regulating G2/M transition in response to DNA damage induced by oxidative stress. Model predictions indicate that the p53 dependent pathway is not required for initial G2 arrest as the Chk1/Cdc25C pathway can arrest the ce
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Collins, Corolyn J., Richard B. Levene, Christina P. Ravera, Marker J. Dombalagian, David M. Livingston, and Dennis C. Lynch. "MOLECULAR CLONING OF THE HUMAN GENE FOR VON WILLEBRAND FACTOR AND IDENTIFICATION OF THE TRANSCRIPTION INITIATION SITE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642830.

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Most patients with von Willebrand's disease appear to have a defect affecting the level of expression of the von Willebrand factor (vWf) gene. Thus, an understanding of the pathogenesis of von Willebrand's disease will require an analysis of the structure and function of the vWf gene in normals and in patients. To begin such analyses, we have screened a human genomic cosmid library with probes obtained from vWf cDNA and isolated a colinear segment spanning ≈175 kb in five overlapping clones. This segment extends ≈25 kb upstream and ≈5 kb downstream of the transcription start and stop sites for
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"Detailed analysis of distribution of repetitive sequences across genomes of Martes (Mustelidae, Carnivora, Mammalia)." In Bioinformatics of Genome Regulation and Structure/Systems Biology (BGRS/SB-2022) :. Institute of Cytology and Genetics, the Siberian Branch of the Russian Academy of Sciences, 2022. http://dx.doi.org/10.18699/sbb-2022-072.

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Reports on the topic "Mammalian genomics"

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Seroussi, Eyal, and George Liu. Genome-Wide Association Study of Copy Number Variation and QTL for Economic Traits in Holstein Cattle. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7593397.bard.

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Copy number variation (CNV) has been recently identified in human and other mammalian genomes and increasing awareness that CNV might be a major source for heritable variation in complex traits has emerged. Despite this, little has been published on CNVs in Holsteins. In order to fill this knowledge-gap, we proposed a genome-wide association study between quantitative trait loci (QTL) for economic traits and CNV in the Holstein cattle. The approved feasibility study was aimed at the genome-wide characterization of CNVs in Holstein cattle and at the demonstrating of their possible association w
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Sadot, Einat, Christopher Staiger, and Zvi Kam Weizmann. functional genomic screen for new plant cytoskeletal proteins and the determination of their role in actin mediated functions and guard cells regulation. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7587725.bard.

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The original objectives of the approved proposal were: 1. To construct a YFP fused Arabidopsis cDNA library in a mammalian expression vector. 2. To infect the library into a host fibroblast cell line and to screen for new cytoskeletal associated proteins using an automated microscope. 3. Isolate the new genes. 4. Characterize their role in plants. The project was approved as a feasibility study to allow proof of concept that would entail building the YFP library and picking up a couple of positive clones using the fluorescent screen. We report here on the construction of the YFP library, the d
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Jander, Georg, Gad Galili, and Yair Shachar-Hill. Genetic, Genomic and Biochemical Analysis of Arabidopsis Threonine Aldolase and Associated Molecular and Metabolic Networks. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7696546.bard.

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Since the amino acids threonine and isoleucine can be limiting in mammalian diet and there is interest in increasing their abundance in certain crop plants. To meet this need, a BARD proposal was written with two main research objectives: (i) investigate new avenues for manipulating threonine and isoleucine content in plants and (ii) study the role of threonine aldolase in plant metabolism. Research conducted to meet these goals included analysis of the sub-cellular localization of threonine aldolase in the plant, analysis of metabolic flux in developing embryos, over- and under-expression of
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Ehrlich, Marcelo, John S. Parker, and Terence S. Dermody. Development of a Plasmid-Based Reverse Genetics System for the Bluetongue and Epizootic Hemorrhagic Disease Viruses to Allow a Comparative Characterization of the Function of the NS3 Viroporin in Viral Egress. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7699840.bard.

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Project Title: "Development of a plasmid-based reverse genetics system for the Bluetongue and Epizootic Hemorrhagic Disease viruses to allow comparative characterization of the function of the NS3 viroporin in viral egress". Project details: No - IS-4192-09; Participants – Ehrlich M. (Tel Aviv University), Parker J.S. (Cornell University), DermodyT.S. (Vanderbilt University); Period - 2009-2013. Orbiviruses are insect-borne infectious agents of ruminants that cause diseases with considerable economical impact in Israel and the United States. The recent outbreaks of BTV in Europe and of Epizoot
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