Academic literature on the topic 'Manipulation (Therapeutics)'

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Journal articles on the topic "Manipulation (Therapeutics)"

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Hao, Mengling, Jiabao Tang, Shengxiang Ge, Tingdong Li, and Ningshao Xia. "Bacterial-Artificial-Chromosome-Based Genome Editing Methods and the Applications in Herpesvirus Research." Microorganisms 11, no. 3 (February 26, 2023): 589. http://dx.doi.org/10.3390/microorganisms11030589.

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Herpesviruses are major pathogens that infect humans and animals. Manipulating the large genome is critical for exploring the function of specific genes and studying the pathogenesis of herpesviruses and developing novel anti-viral vaccines and therapeutics. Bacterial artificial chromosome (BAC) technology significantly advanced the capacity of herpesviruses researchers to manipulate the virus genomes. In the past years, advancements in BAC-based genome manipulating and screening strategies of recombinant BACs have been achieved, which has promoted the study of the herpes virus. This review su
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Almeida-Porada, Graça D. "Stem cell gene manipulation and delivery as systemic therapeutics." Advanced Drug Delivery Reviews 62, no. 12 (September 2010): 1139–40. http://dx.doi.org/10.1016/j.addr.2010.10.005.

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Juliano, Rudolph L. "Chemical Manipulation of the Endosome Trafficking Machinery: Implications for Oligonucleotide Delivery." Biomedicines 9, no. 5 (May 5, 2021): 512. http://dx.doi.org/10.3390/biomedicines9050512.

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Antisense oligonucleotides (ASOs), siRNA and splice switching oligonucleotides (SSOs) all have immense potential as therapeutic agents, potential that is now being validated as oligonucleotides enter the clinic. However, progress in oligonucleotide-based therapeutics has been limited by the difficulty in delivering these complex molecules to their sites of action in the cytosol or nucleus of cells within specific tissues. There are two aspects to the delivery problem. The first is that most types of oligonucleotides have poor uptake into non-hepatic tissues. The second is that much of the olig
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Wang, Ziyi, Pengchao Sun, Jingjing Su, Nan Zhang, Hongzhou Gu, and Yongxing Zhao. "DNA nanotechnology-facilitated ligand manipulation for targeted therapeutics and diagnostics." Journal of Controlled Release 340 (December 2021): 292–307. http://dx.doi.org/10.1016/j.jconrel.2021.11.004.

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Wu, Yingjie, Yining Chen, Xiaochun Yu, Minxing Zhang, and Zhaoyu Li. "Towards Understanding Neurodegenerative Diseases: Insights from Caenorhabditis elegans." International Journal of Molecular Sciences 25, no. 1 (December 28, 2023): 443. http://dx.doi.org/10.3390/ijms25010443.

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The elevated occurrence of debilitating neurodegenerative disorders, such as amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD), Alzheimer’s disease (AD), Parkinson’s disease (PD) and Machado–Joseph disease (MJD), demands urgent disease-modifying therapeutics. Owing to the evolutionarily conserved molecular signalling pathways with mammalian species and facile genetic manipulation, the nematode Caenorhabditis elegans (C. elegans) emerges as a powerful and manipulative model system for mechanistic insights into neurodegenerative diseases. Herein, we review several representative C.
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Shanahan, Fergus. "Physiological Basis for Novel Drug Therapies Used to Treat the Inflammatory Bowel Diseases I. Pathophysiological basis and prospects for probiotic therapy in inflammatory bowel disease." American Journal of Physiology-Gastrointestinal and Liver Physiology 288, no. 3 (March 2005): G417—G421. http://dx.doi.org/10.1152/ajpgi.00421.2004.

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Mechanisms underlying the conditioning influence of the intestinal flora on mucosal homeostasis, including development and function of immune responses, are attracting increasing scientific scrutiny. The intestinal flora is a positive asset to host defense, but some of its components may, in genetically susceptible hosts, become a risk factor for development of inflammatory bowel disease (IBD). It follows that strategies to enhance assets or offset microbial liabilities represent a therapeutic option; therein lies the rationale for manipulation of the flora in IBD. In addition, the diversity o
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Papageorgiou, Maria, and Emmanuel Biver. "Interactions of the microbiome with pharmacological and non-pharmacological approaches for the management of ageing-related musculoskeletal diseases." Therapeutic Advances in Musculoskeletal Disease 13 (January 2021): 1759720X2110090. http://dx.doi.org/10.1177/1759720x211009018.

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Despite major progress in the understanding of the pathophysiology and therapeutic options for common ageing-related musculoskeletal conditions (i.e. osteoporosis and associated fractures, sarcopenia and osteoarthritis), there is still a considerable proportion of patients who respond sub optimally to available treatments or experience adverse effects. Emerging microbiome research suggests that perturbations in microbial composition, functional and metabolic capacity (i.e. dysbiosis) are associated with intestinal and extra-intestinal disorders including musculoskeletal diseases. Besides its c
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Brown, Thomas J., and Victoria James. "The Role of Extracellular Vesicles in the Development of a Cancer Stem Cell Microenvironment Niche and Potential Therapeutic Targets: A Systematic Review." Cancers 13, no. 10 (May 18, 2021): 2435. http://dx.doi.org/10.3390/cancers13102435.

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Cancer stem cells (CSCs) have increasingly been shown to be a crucial element of heterogenous tumors. Although a relatively small component of the population, they increase the resistance to treatment and the likelihood of recurrence. In recent years, it has been shown, across multiple cancer types (e.g., colorectal, breast and prostate), that reciprocal communication between cancer and the microenvironment exists, which is, in part, facilitated by extracellular vesicles (EVs). However, the mechanisms of this method of communication and its influence on CSC populations is less well-understood.
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Bondhopadhyay, Banashree, Sandeep Sisodiya, Faisal Abdulrahman Alzahrani, Muhammed A. Bakhrebah, Atul Chikara, Vishakha Kasherwal, Asiya Khan, et al. "Exosomes: A Forthcoming Era of Breast Cancer Therapeutics." Cancers 13, no. 18 (September 17, 2021): 4672. http://dx.doi.org/10.3390/cancers13184672.

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Despite the recent advancements in therapeutics and personalized medicine, breast cancer remains one of the most lethal cancers among women. The prognostic and diagnostic aids mainly include assessment of tumor tissues with conventional methods towards better therapeutic strategies. However, current era of gene-based research may influence the treatment outcome particularly as an adjunct to diagnostics by exploring the role of non-invasive liquid biopsies or circulating markers. The characterization of tumor milieu for physiological fluids has been central to identifying the role of exosomes o
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Mahajan, Kalpesh D., Gang Ruan, Greg Vieira, Thomas Porter, Jeffrey J. Chalmers, R. Sooryakumar, and Jessica O. Winter. "Biomolecular detection, tracking, and manipulation using a magnetic nanoparticle-quantum dot platform." Journal of Materials Chemistry B 8, no. 16 (2020): 3534–41. http://dx.doi.org/10.1039/c9tb02481f.

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Fluorescent and magnetic materials play a significant role in biosensor technology, enabling sensitive quantification and separations with applications in diagnostics, purification, quality control, and therapeutics.
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Dissertations / Theses on the topic "Manipulation (Therapeutics)"

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Simmonds, Marian. "The effect of neck manipulation on excitability of the motor cortex thesis submission to Auckland University of Technology in partial fulfilment of the degree of Master of Health Science, 2004." Full thesis. Abstract, 2004.

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Duffy, Margaret R. "Investigation and manipulation of adenovirus interactions with host proteins." Thesis, University of Glasgow, 2012. http://theses.gla.ac.uk/3582/.

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Adenoviruses are the most commonly used vectors for clinical gene therapy applications, accounting for 24% of all clinical trials to date, the majority of which are based on Ad serotype 5 (Ad5). However, the high prevalence of neutralising antibodies and a range of “off target” interactions result in liver sequestration, hepatic transduction and decreased circulation times. Such interactions include Kupffer cell uptake and binding to blood components such as erythrocytes, platelets, complement and coagulation factors. Recent studies have shown that hepatocyte transduction by Ad5 is mediated by
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"Reflex motorneuron excitability of the musculocutaneous nerve in the biceps brachii muscle after upper cervical or cervicothoracic spinal manipulative therapy." Thesis, 2009. http://hdl.handle.net/10210/2671.

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"A treatment protocol for the treatment of cervical facet syndrome comparing the use of cryotherapy before or after the chiropractic adjustment." Thesis, 2009. http://hdl.handle.net/10210/2679.

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"The effects of chiropractic spinal manipulation on driver club head speeds of asymptomatic amateur golfers." Thesis, 2009. http://hdl.handle.net/10210/2695.

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White, Stuart J. "A study to determine the role of soft tissue therapy in the chiropractic management of cervical facet syndrome." Thesis, 2009. http://hdl.handle.net/10210/2646.

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Stacey, Leandra R. "An investigation to determine whether the combination of a hip mobilisation and sacroiliac adjustment or a hip mobilisation alone is more effective in the treatment of osteoarthritis of the hip." Thesis, 2009. http://hdl.handle.net/10210/2688.

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Swartz, Brett. "The immediate effect of cervicothoracic junction manipulation on triceps muscle strength." Thesis, 2009. http://hdl.handle.net/10210/2689.

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Sher, Gregory Colin. "The effect of sacroiliac joint manipulation on quadriceps muscle strength." Thesis, 2009. http://hdl.handle.net/10210/2694.

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Herwill, Dylan Marc. "A study of the effect of chiropractic adjustment therapy of the tibiotalar joint and strengthening of the gastrocnemius muscle." Thesis, 2010. http://hdl.handle.net/10210/3136.

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M. Tech.<br>The aim of this study was to determine whether a combination treatment of strength training of the Gastrocnemius muscle and adjusting of the Tibiotalar joint would have a greater effect and influence on the strength of the Gastrocnemius muscles when compared to either strengthening the Gastrocnemius muscles or adjusting the Tibiotalar joints alone. Thirty participants from the surrounding community of the University of Johannesburg were randomly divided into one of three groups, with an equal male to female ratio within each group. Group A received a strength training protocol dire
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Books on the topic "Manipulation (Therapeutics)"

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C, Gordon Robert, ed. Manipulation under anesthesia: Concepts in theory and application. Boca Raton, FL: CRC Press, 2005.

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Fred, Hoehler, ed. Musculoskeletal manipulation: Evaluation of the scientific evidence. Springfield, Ill., U.S.A: Thomas, 1986.

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Jennie, Longbottom, ed. Acupuncture in manual therapy. Edinburgh: Churchill Livingstone, 2010.

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Jinxue, Li. Chinese manipulation and massage: Chinese manipulative therapy (CMT). Oxford [England]: International Academic Publishers, 1990.

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Byfield, David. Technique skills in chiropractic. Edinburgh: Churchill Livingstone/Elsevier, 2012.

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Nathan, Bevis. Touch and emotion in manual therapy. Edinburgh: Churchill Livingstone, 1999.

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Maitland, G. D. Peripheral manipulation. 3rd ed. Oxford: Butterworth-Heinemann, 1999.

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Hebgen, Eric. Visceral manipulation in osteopathy. Stuttgart: Thieme, 2011.

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Beeton, Karen. The peripheral joints. Edinburgh: Churchill Livingstone, 2003.

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D, Maitland G., ed. Maitland's vertebral manipulation. 6th ed. Oxford: Butterworth-Heinemann, 2001.

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Book chapters on the topic "Manipulation (Therapeutics)"

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Cook, John R., Kaylee V. Bennett, Michael C. Barton, and Steven M. Platek. "SARS/CoV-2: Behavioral Host Manipulation." In Coronavirus Therapeutics – Volume II, 71–80. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-85113-2_4.

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Mollnes, Tom Eirik. "Therapeutic Manipulation of the Complement System." In The Complement System, 483–516. Boston, MA: Springer US, 2004. http://dx.doi.org/10.1007/1-4020-8056-5_23.

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Kadian, Monika, and Anil Kumar. "Psychobiotics for Manipulating Gut–Brain Axis in Alzheimer’s Disease." In Probiotic Research in Therapeutics, 135–53. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-6760-2_6.

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von der Leyen, H. E., and V. J. Dzau. "Therapeutic Potential of Nitric Oxide Synthase Gene Manipulation." In Nitric Oxide, 639–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57077-3_25.

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Ali, Mudassar, Jyotirmoy Rajurkar, Priyanka Majumder, Mainak Pratim Jha, Rajasri Sarkar, and Koyeli Mapa. "Possible Therapeutic Intervention Strategies for COVID-19 by Manipulating the Cellular Proteostasis Network." In Coronavirus Therapeutics – Volume I, 125–47. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-85109-5_8.

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Charron, Maureen J., and Ellen B. Katz. "Metabolic and therapeutic lessons from genetic manipulation of GLUT4." In Insulin Action, 143–52. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5647-3_15.

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Watson, Alastair, and Pedro Lowenstein. "Therapeutic manipulation of apoptosis in cancer and neurological disease." In Apoptosis Genes, 281–303. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5287-1_10.

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Henderson, I. C. "State of the art in cytotoxic manipulation in treatment of metastatic breast cancer." In Therapeutic Management of Metastatic Breast Cancer, edited by M. Kaufmann, I. C. Henderson, and E. Enghofer, 19–32. Berlin, Boston: De Gruyter, 1989. http://dx.doi.org/10.1515/9783110888942-003.

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Shephard, J., S. Brett, and T. W. Evans. "Therapeutic Manipulation of the Pulmonary Circulation in Acute Lung Injury." In Yearbook of Intensive Care and Emergency Medicine, 311–20. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-79154-3_25.

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Sinha, Lovely, and Saurabh Karmakar. "Traditional Herbal Medicines, Bioactive Compounds, and Plant Products as Therapeutic Approach Against Interstitial Lung Disease." In Genetic Manipulation of Secondary Metabolites in Medicinal Plant, 339–80. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-4939-7_15.

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Conference papers on the topic "Manipulation (Therapeutics)"

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Nguyen, Van Du, Shaohui Zheng, Viet Ha Le, Jiwon Han, and Jong-Oh Park. "Manipulation of tumor targeting cell-based microrobots carrying NIR light sensitive therapeutics using EMA system and chemotaxis." In 2017 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS). IEEE, 2017. http://dx.doi.org/10.1109/marss.2017.8001911.

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Batabyal, Subrata, Sanghoon Kim, Michael Carlson, Houssam Al-Saad, Jazlyn Gallego, Adnan Dibas, and Samarendra K. Mohanty. "Neuroprotection by optical delivery of therapeutic gene into retina." In Optogenetics and Optical Manipulation 2021, edited by Samarendra K. Mohanty, Anna W. Roe, and Shy Shoham. SPIE, 2021. http://dx.doi.org/10.1117/12.2586104.

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Julias, Margaret, Helen M. Buettner, and David I. Shreiber. "The Biophysical Response of Collagen-Fibrin Composite Gels to In Vitro Acupuncture." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19221.

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Therapeutic acupuncture involves the insertion and manipulation of fine needles at specific points. Although acupuncture has been proven effective for a number of conditions, the mechanisms that underlay these effects remain unknown. A critical first step is to identify the local changes that occur during needle manipulation, which can then be related to longer-term and more remote consequences. In vivo and ex vivo studies have demonstrated that loose collagenous subcutaneous connective tissue couples to needles during therapeutic manipulation, which deforms the tissue and exposes resident cel
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Miron, Geneviève, Alexandre Girard, Jean-Sébastien Plante, and Martin Lepage. "Design and Manufacturing of Embedded Pneumatic Actuators for an MRI-Compatible Prostate Cancer Binary Manipulator." In ASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/detc2012-71380.

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Magnetic Resonance Imaging (MRI) compatible robots can assist physicians in precisely inserting biopsy needles or therapeutic instruments directly into millimeter-size tumors using MR imaging feedback. MRI systems although present a challenging environment, including high magnetic fields and limited space, making the development of MRI-compatible robots complex. This paper presents an MRI-compatible pneumatic actuation technology consisting of molded polymer structures with embedded air-muscle, operated in a binary fashion. While having good positioning accuracy, the technology presents advant
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Gao, Shiqiang, and Georg Nagel. "Development and applications of Optogenetic tools for manipulation of cyclic nucleotides." In cGMP: Generators, Effectors and Therapeutic Implications. ScienceOpen, 2024. http://dx.doi.org/10.14293/cgmp.24000051.v1.

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Finlay, P. A. "Robotic controlled endoscopic manipulator." In IEE Colloquium on Technological Advances in Therapeutic Urology. IEE, 1996. http://dx.doi.org/10.1049/ic:19960626.

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Ort, Teddy, Faye Wu, Nicholas C. Hensel, and H. Harry Asada. "Supernumerary Robotic Fingers as a Therapeutic Device for Hemiparetic Patients." In ASME 2015 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/dscc2015-9945.

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Patients with hemiparesis often have limited functionality in the left or right hand. The standard therapeutic approach requires the patient to attempt to make use of the weak hand even though it is not functionally capable, which can result in feelings of frustration. Furthermore, hemiparetic patients also face challenges in completing many bimanual tasks, for example walker manipulation, that are critical to patients’ independence and quality of life. A prototype therapeutic device with two supernumerary robotic fingers was used to determine if robotic fingers could functionally assist a hum
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Deng, Chongli, Jian Li, Xuewei Cao, Jun Liu, Tao Yu, and Da Guo. "Therapeutic effectiveness evaluation on Shishi manipulation for knee osteoarthritis." In 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW). IEEE, 2012. http://dx.doi.org/10.1109/bibmw.2012.6470376.

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Zheng, Shaohui, Sunghoon Cho, Van Du Nguyen, Eunpyo Choi, Jiwon Han, and Jong-Oh Park. "Development of hyaluronic acid microcargo for therapeutic bacteriobots." In 2017 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS). IEEE, 2017. http://dx.doi.org/10.1109/marss.2017.8001912.

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Brewer, B. R., R. Klatzky, and Y. Matsuoka. "Initial Therapeutic Results of Visual Feedback Manipulation in Robotic Rehabilitation." In 2006 International Workshop on Virtual Rehabilitation. IEEE, 2006. http://dx.doi.org/10.1109/iwvr.2006.1707546.

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Reports on the topic "Manipulation (Therapeutics)"

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Research, Gratis. Green Light: A New Preventive Therapy for Migraine. Gratis Research, November 2020. http://dx.doi.org/10.47496/gr.blog.03.

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Manipulating the ability of green light to create the least amount of electrical signals in retina and brain cortex, green light therapy offers an excellent therapeutic role in reducing migraine pain and improves the quality of life
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Yull, Fiona E. Manipulation of NF-KappaB Activity in the Macrophage Lineage as a Novel Therapeutic Approach. Fort Belvoir, VA: Defense Technical Information Center, May 2005. http://dx.doi.org/10.21236/ada439787.

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Yull, Fiona. Manipulation of Nf-KappaB Activity in the Macrophage Lineage as a Novel Therapeutic Approach. Fort Belvoir, VA: Defense Technical Information Center, May 2008. http://dx.doi.org/10.21236/ada487648.

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Yull, Fiona E. Manipulation of NF-KappaBetta Activity in the Macrophage Lineage as a Novel Therapeutic Approach. Fort Belvoir, VA: Defense Technical Information Center, May 2007. http://dx.doi.org/10.21236/ada471493.

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