Academic literature on the topic 'Mannich bases'
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Journal articles on the topic "Mannich bases"
Yamali, Cem, Halise Inci Gul, Tahir Cakir, Yeliz Demir, and Ilhami Gulcin. "Aminoalkylated Phenolic Chalcones: Investigation of Biological Effects on Acetylcholinesterase and Carbonic Anhydrase I and II as Potential Lead Enzyme Inhibitors." Letters in Drug Design & Discovery 17, no. 10 (October 12, 2020): 1283–92. http://dx.doi.org/10.2174/1570180817999200520123510.
Full textHajiyeva, G. E., E. H. Mammadbayli, S. I. Ibrahimli, and I. A. Jafarov. "NORBORNENE-CONTAINING MANNICH BASES ON THE BASIS OF ALIPHATIC AMINES." Azerbaijan Chemical Journal, no. 3 (2018): 50–56. http://dx.doi.org/10.32737/0005-2531-2018-3-50-56.
Full textBala, Suman, Neha Sharma, Anu Kajal, Sunil Kamboj, and Vipin Saini. "Mannich Bases: An Important Pharmacophore in Present Scenario." International Journal of Medicinal Chemistry 2014 (November 12, 2014): 1–15. http://dx.doi.org/10.1155/2014/191072.
Full textPanda, Jnyanaranjan. "Synthesis and Biological Evaluation of Some Isatin-based Mannich Bases." International Journal of Pharmaceutical Sciences and Nanotechnology 5, no. 4 (February 28, 2013): 1841–46. http://dx.doi.org/10.37285/ijpsn.2012.5.4.3.
Full textDimmock, J. R., and P. Kumar. "Anticancer and Cytotoxic Properties of Mannich Bases." Current Medicinal Chemistry 4, no. 1 (February 1997): 1–22. http://dx.doi.org/10.2174/0929867304666220309194437.
Full textSETHI, RITCHU, SANDEEP ARORA, NEELAM JAIN, and SANDEEP JAIN. "Mannich Bases of 2-Substituted Benzimidazoles - A Review." JOURNAL OF PHARMACEUTICAL TECHNOLOGY, RESEARCH AND MANAGEMENT 3, no. 2 (November 2, 2015): 97–111. http://dx.doi.org/10.15415/jptrm.2015.32008.
Full textDeo, Prem Shankar, Rhambus Rawat, and Bhushan Shakya. "Synthesis, Characterization and Antimicrobial Evaluation of Mannich Bases of 4-(Furan-2-yl-methyleneamino)-3-(2-hydroxyphenyl)-1H-1,2,4-triazole-5-thione." Journal of Nepal Chemical Society 42, no. 1 (March 1, 2021): 6–15. http://dx.doi.org/10.3126/jncs.v42i1.35322.
Full textComanita, Eugenia, Gheorghe Roman, Irina Popovici, and Bogdan Comanita. "Synthesis and reactivity of some mannich bases. VIII. Studies on several mannich bases derived from ortho-hidroxyacetophenones and their conversion into oximino derivatives." Journal of the Serbian Chemical Society 66, no. 1 (2001): 9–16. http://dx.doi.org/10.2298/jsc0101009c.
Full textLi, Ke Hua, Bing Bing Yang, Zhi Wei Lan, Ren Fang Wang, and Tie Jun Su. "The Research of Thiosemicarbazide Modified as Acidizing Corrosion Inhibitor." Applied Mechanics and Materials 723 (January 2015): 605–9. http://dx.doi.org/10.4028/www.scientific.net/amm.723.605.
Full textJournal, Baghdad Science. "Synthesis And Characterization Of Some New Acetylenic Mannich Bases Based On Biphenyl – 4,4 - Dithiol." Baghdad Science Journal 10, no. 3 (September 1, 2013): 712–23. http://dx.doi.org/10.21123/bsj.10.3.712-723.
Full textDissertations / Theses on the topic "Mannich bases"
Trossini, Gustavo Henrique Goulart. "Antichagásicos potenciais: síntese de bases de Mannich do hidroximetilnitrofural." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/9/9138/tde-28102010-104123/.
Full textChaga\'s disease is an endemic disease that aftects most part of Latin Arnerica. About 18 to 20 million people are infected by the parasite and around 50 thousand deaths are related to Chagas\' disease each year, in the 21 countries of endemic areas. The therapeutic armamentarium available against the disease is constituted by only two drugs and is insufficient, considering, also, that the drugs are not efficient in the chronic phase of the disease. As a parasitosis that only occurs in developing countries, the interest in the research for new antichagasic agents is considerably low in countries that are responsible for the introduction of new drugs in the therapeutics. So, the search for new chemotherapeutic alternatives is a task for the involved countries. In view of the situation and taking into account the high activity in in vitro tests against Trypanosoma cruzi showed by nitrofurazone hydroxymethyl derivative, an intermediary of Mannich bases reaction previously synthesized, the objective of this work was to synthesize its Mannich bases. The carriers used were aminoacids lysine and arginine and its dipeptide, lysinearginine. The compounds were synthesized using classic and alternative methods and protecting groups, currently used in peptide synthesis and others temptatively employed, as methyl and ethyl groups. Also, many experiments were performed in order to achieve the optimization of hydroxymethylnitrofurazone synthesis. The derivatives synthesized were analyzed by IR, 1H and 13C NMR, and some also by mass spectrometry. They will be submitted to in vitro tests with cell infected with T. cruzi as soon as the protecting groups are removed. Besides, tests of drug release will be performed to study their stability. We expect to obtain important information toward better comprehension of their mechanism of action and possible mutagenicity involved.
Roche, Maxime. "Etude des 3,4-Dihydro-2H-1, 3-Benzoxzazines : Réactivité - Polymérisation." Besançon, 1989. http://www.theses.fr/1989BESA2039.
Full textKandepu, Narayana Murthi. "Mannich bases of chalcones and cyclohexanones as candidate cytotoxic agents." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0035/NQ63974.pdf.
Full textHermange, Philippe. "Réaction de Mannich vinylogue diastéréosélective entre des sels d’isoquinolinium et des silyloxyfuranesApplication à la synthèse de nouveaux ligands du récepteur GABA-A et à des analogues de l’émétine." Paris 11, 2009. http://www.theses.fr/2009PA112200.
Full textStarting from the high diastereoselectivity observed in the vinylogous Mannich reaction between an isoquinolinium salt and a silyloxyfuran, various research themes were developed during this thesis. First, the scope of the reaction was determined and a methodological study showed that good yields and diastereoselectivities superior to 80% are generally obtained. After optimization of a three component procedure, the reaction was extended to formation of quaternary centers and use of silyloxypyrroles. The importance of the C3-C4 double bond of isoquinoline in favoring the R*,R* configuration was explained by molecular modeling. An asymmetric version of the reaction was also studied and good results were obtained with chiral auxiliaries whereas thiourea-based organocatalysts provided only low enantioselectivities. This diastereoselective vinylogous Mannich reaction was then applied to two medicinal chemistry fields. Thus, several isoquinoline-butyrolactones proved to be potent positive allosteric modulators of the GABA-A receptor (potential anxiolytics). Furthermore, a novel access to a 2nd generation of 1,4-disubstituted compounds was validated. Finally, a short synthesis (6 steps) of emetine analogs having potential anti-tumor properties was developed using our methodology as the key step. The perspectives of this work are presented in the general conclusion
Ward, Nathan Andrew. "Resurrection of Organophosphorus-Aged Acetylcholinesterase via Mannich Bases Derived from Proline." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1565714137331736.
Full textGhaib, Amar. "Pharmacomodulation autour du squelette octahydropyrimido[3,4-a]-s-triazines : introduction de restes alkyles de lipophilie croissante." Rouen, 2001. http://www.theses.fr/2001ROUE03NR.
Full textIminodimethylation of 6 monoalkyl and dialkyl 5-aminopyrimidinediones by various primary amines was studied. The synthesis of these synthons was performed from ethyl cyanacetates, previously alkylated in 2 position, which reacted with area in alkaline medium. Alkylation of the strongly activated methylenes, situated between a nitrile and an ester groupe, in alkaline medium, leads to a mixture of unalkylated, monoalkylated and dialkylated derivatives. It was then necessary to use the différences of solubilities of the salts of theses compounds to separated them. In order to avoid these difficulties, two other synthetic pathways were used. Iminodimethylation of these synthons yielded 24 octahydropyrimido[3,4-a]-striazines, variously dialkylated, which were submitted to an automated pharmacological screening, especially in the area of antimicrobial agents. A series of 23 pyrimido[3,4-a]-s-triazines monoalkylated in position 9 were synthetized by iminodimethylation of 5-monoalkyl-6-aminopyrimidine 1,3-diones. It was shown that the structure was triazinic and not pyrimido pyrimidinic as it could have been. These compounds, despite a good overlay with Ketanserin, a well known anti 5-HT2, only showed a weak activity in automated screening
Al-Sarabi, Alaeddin. "Application de la réaction de Mannich intramoléculaire à la synthèse d'hétérocycles azotés." Clermont-Ferrand 2, 2004. http://www.theses.fr/2004CLF21491.
Full textVashishtha, Sarvesh Chandra. "Mannich bases and other related compounds designed principally as candidate cytotoxic and anticancer agents." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq23886.pdf.
Full textThomas, Anne. "Synthèse de dérivés pipéridiniques sur support solide." Clermont-Ferrand 2, 2004. http://www.theses.fr/2004CLF21499.
Full textTEDLAOUTI, FATIHA. "Pharmacologie antimalarique et trypanocide de derives thiopheniques, de bases de mannich et de saponosides d'hedera helix l. , calendula arvensis l. Et de sapendus mukurosi l." Aix-Marseille 2, 1991. http://www.theses.fr/1991AIX22957.
Full textBooks on the topic "Mannich bases"
Luigi, Angiolini, ed. Mannich bases: Chemistry and uses. Boca Raton: CRC Press, 1994.
Find full textChalliner, John Francis. Photochemistry of imide mannich bases. Wolverhampton: The Polytechnic, Wolverhampton, Department of Physical Sciences, 1985.
Find full textIrving, Washington. The Sketch-Book of Geoffrey Crayon, Gent. Edited by Susan Manning. Oxford University Press, 2009. http://dx.doi.org/10.1093/owc/9780199555819.001.0001.
Full textBook chapters on the topic "Mannich bases"
Seeni Mubarak, M., R. Kathirvel, M. Sathyanarayanan, and S. Mohamed Rabeek. "Some Novel Mannich Bases-Synthesis, Crystal Structure, Docking Studies, Anti-microbial Activity, and Cytotoxicity." In Springer Proceedings in Physics, 685–708. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-44890-9_56.
Full textKoll, Aleksander, and Peter Wolschann. "Mannich Bases as Model Compounds for Intramolecular Hydrogen Bonding II [1] Structure and Properties in Solution." In Hydrogen Bond Research, 39–57. Vienna: Springer Vienna, 1999. http://dx.doi.org/10.1007/978-3-7091-6419-8_3.
Full textColacio, Enrique. "Mannich Base Ligands as Versatile Platforms for SMMs." In Topics in Organometallic Chemistry, 101–61. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/3418_2018_4.
Full textPardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) complex with Mannich base, N-(morpholinobenzyl)-benzamide." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 4, 247–48. Berlin, Heidelberg: Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62474-6_107.
Full textPetty, Stephen D., and Lyn Hester. "“Manning Up for Men’s Health”: Sports Radio and the INTEGRIS Men’s Health University, Oklahoma, USA." In Sports-Based Health Interventions, 291–96. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4614-5996-5_24.
Full textPietraszkiewicz, Oksana, Małgorzata Koźbiał, and Marek Pietraszkiewicz. "Transport Studies of Inorganic and Organic Cations Across Liqued Membranes Containing Mannich-Base Calix[4]Resorcinarenes." In Molecular Recognition and Inclusion, 459–62. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5288-4_83.
Full textAl-Mamari, Mahmood M., Sameh A. Kantoush, and Tetsuya Sumi. "Innovative Monitoring Techniques for Wadi Flash Flood by Using Image-Based Analysis." In Natural Disaster Science and Mitigation Engineering: DPRI reports, 251–66. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2904-4_9.
Full textBlack, D. StC. "Substitution Reactions of Mannich Bases." In Fully Unsaturated Small-Ring Heterocycles and Monocyclic Five-Membered Hetarenes with One Heteroatom, 1. Georg Thieme Verlag KG, 2001. http://dx.doi.org/10.1055/sos-sd-009-00657.
Full textP, Sounthari, and Sivakumar P.R. "Schiff Bases - Interesting Range of Applications in Various Fields of Science." In Synthesis and Characterization of Some Novel Mannich Base Compounds, 21–37. IOR INTERNATIONAL PRESS, 2019. http://dx.doi.org/10.34256/ioriip1982.
Full textHof, K., K. M. Lippert, and P. R. Schreiner. "Mannich Reaction." In Brønsted Base and Acid Catalysts, and Additional Topics, 1. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-205-00228.
Full textConference papers on the topic "Mannich bases"
Funar-Timofei, Simona, Ana Borota, Alina Bora, Sorin Avram, and Daniela Ionescu. "QSAR MODELING ON FUNGICIDAL ACTIVITY OF MANNICH BASES." In The 19th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2015. http://dx.doi.org/10.3390/ecsoc-19-e005.
Full textVerigina, Anastasiia Alexseevna, Tatiana Sergeevna Stepanova, and Pavel Iosifovich Pinko. "PREPARATION OF ALKYLTHIOMETHYLATED DERIVATIVES OF 2,4-DI-TERT-BUTYLPHENOL AND PRELIMINARY ASSESSMENT OF THEIR ANTIOXIDANT ACTIVITY." In IX Международная научно-практическая конференция "Инновационные аспекты развития науки и техники". KDU, Moscow, 2021. http://dx.doi.org/10.31453/kdu.ru.978-5-7913-1190-0-2021-6-14.
Full textAllochio Filho, J. F., L. L. Roldi, R. Fiorot, S. J. Greco, V. Lacerda Jr., R. B. dos Santos, E. V. R. de Castro, et al. "Synthesis and in vitro antifungal activity of new Mannich bases derived from 2-hydroxy-1,4-naphthoquinone (Lawsone)." In 15th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013916122532.
Full textHe, Meng, Haoyuan Kang, Juanbo Liu, Sheng Chen, Xueru Gong, and Li Sun. "Development of Inhibitor for Corrosion Protection of Condensate Stripping Process in Industrial Coal Gasification Unit." In ASME 2021 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/pvp2021-61869.
Full textLaGrange, Elgonda, Brett Bollinger, and Ali Elnaamani. "Digitally Transforming Offshore Production: Making Low-Manned Brownfield Installations a Reality." In Offshore Technology Conference. OTC, 2021. http://dx.doi.org/10.4043/30996-ms.
Full textRodríguez, Laura, Elena Viqueira, Oscar Souto, and Antonio Sousa-Pedrares. "Synthesis and characterization of new Mannich base ligand. Structure of N, N-bis-(4,5-dimethyl-2-hydroxybenzyl)-N(2-pyridylmethyl)amine." In The 10th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2006. http://dx.doi.org/10.3390/ecsoc-10-01414.
Full textChaithra, N., P. C. Shruthi, V. Rashmi, V. Akhil, and S. S. M. Saqquaf. "An IoT Based Railway Security System for Automated Manning at Level Crossings." In 2018 3rd IEEE International Conference on Recent Trends in Electronics, Information & Communication Technology (RTEICT). IEEE, 2018. http://dx.doi.org/10.1109/rteict42901.2018.9012435.
Full textZHOU, WENJUN. "HOW TO IMPROVE THE ECONOMIC BENEFITS OF HARBOR AS A SHIP." In 2021 INTERNATIONAL CONFERENCE ON ADVANCED EDUCATION AND INFORMATION MANAGEMENT (AEIM 2021). Destech Publications, Inc., 2021. http://dx.doi.org/10.12783/dtssehs/aeim2021/35968.
Full textNguyen, Van Tri, Didier Georges, and Gildas Besancon. "Adjoint-method-based estimation of Manning roughness coefficient in an overland flow model." In 2015 American Control Conference (ACC). IEEE, 2015. http://dx.doi.org/10.1109/acc.2015.7171023.
Full textMacKenzie, Adam, J. O. Miller, and Raymond Hill. "An exploration of the effects of maintenance manning on Combat Mission Readiness utilizing agent based modeling." In 2010 Winter Simulation Conference - (WSC 2010). IEEE, 2010. http://dx.doi.org/10.1109/wsc.2010.5679053.
Full textReports on the topic "Mannich bases"
Kaplan, Jonathan D. A Concept for Developing a Data Base to Aid in System Manning Prediction. Fort Belvoir, VA: Defense Technical Information Center, March 1985. http://dx.doi.org/10.21236/ada161662.
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