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Eyzaguirre, Raúl, and Enit Huamán. "Guia de prácticas de laboratorio." Universidad Peruana de Ciencias Aplicadas - UPC, 2007. http://hdl.handle.net/10757/272702.
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Jaramillo, Vega Segundo Santiago. "Guía de laboratorio 3: muestreo en SPSS." Universidad Peruana de Ciencias Aplicadas - UPC, 2007. http://hdl.handle.net/10757/272704.
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Hurtado, Alendes Ana, and Tapia Ángela Cornejo. "Biología General (MA155), ciclo 2013-1: Guía de Prácticas de Laboratorio." Universidad Peruana de Ciencias Aplicadas - UPC, 2013. http://hdl.handle.net/10757/271704.
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Guía de prácticas de laboratorio para el curso de Biología General (MA155), que se dicta para la Escuela de Odontología y que corresponde al ciclo 2013-1. Esta guía brinda las pautas necesarias para realizar los experimentos en las prácticas de laboratorio.
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Robles, Valcárcel Pamela, and Zea Guillermo Santillán. "Química Orgánica (MA129): Guía de laboratorio, ciclo 2013-2." Universidad Peruana de Ciencias Aplicadas - UPC, 2013. http://hdl.handle.net/10757/296381.
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Manual de laboratorio del curso Química Orgánica (MA129), que corresponde al ciclo 2013-2. Introducción. Normas de bioseguridad en el laboratorio. Laboratorio N° 1: Purificación de compuestos orgánicos. Laboratorio N° 2: Compuestos orgánicos oxigenados. Laboratorio N° 3 : Saponificación. Laboratorio N° 4: Reconocimiento de carbohidratos. Laboratorio Nº 5: Reconocimiento de proteínas y lípidos.
Laboratorio N° 6: Examen práctico.
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Hurtado, Alendes Ana, and Tapia Ángela Cornejo. "Biología General (MA155), ciclo 2013-2: Guía de Prácticas de Laboratorio." Universidad Peruana de Ciencias Aplicadas - UPC, 2013. http://hdl.handle.net/10757/296360.
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Guía de Prácticas de Laboratorio del curso de Biología General (MA155), que corresponde al ciclo 2013-2. Biología General es un curso teórico-práctico dirigido a los alumnos del primer año de la carrera de Odontología, cuyos objetivos son, que el alumno conozca la naturaleza, racionalidad y ordenamiento lógico de la Biología como ciencia, que relacione los conceptos unificadores de la biología para tener una concepción integral del hombre, y que conozca, valore y respete la biodiversidad y el medio ambiente.
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Hurtado, Alendes Ana. "Biología General (MA155), ciclo 2014-1: Guía de Prácticas de Laboratorio." Universidad Peruana de Ciencias Aplicadas - UPC, 2014. http://hdl.handle.net/10757/313863.
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Guía de Prácticas de Laboratorio del curso de Biología General (MA155), que corresponde al ciclo 2014-1. Biología General es un curso teórico-práctico dirigido a los alumnos del primer año de la carrera de Odontología, cuyos objetivos son, que el alumno conozca la naturaleza, racionalidad y ordenamiento lógico de la Biología como ciencia, que relacione los conceptos unificadores de la biología para tener una concepción integral del hombre, y que conozca, valore y respete la biodiversidad y el medio ambiente.
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Córdova, Yamauchi Leslie. "Química General (MA212), ciclo 2013-1: Guía de Laboratorio." Universidad Peruana de Ciencias Aplicadas - UPC, 2013. http://hdl.handle.net/10757/271854.
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Córdova, Yamauchi Leslie. "Química General (MA212): Guia de Prácticas de Laboratorio, ciclo 2013-2." Universidad Peruana de Ciencias Aplicadas - UPC, 2013. http://hdl.handle.net/10757/296653.
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Guía de laboratorio del curso Química General (MA212) para la carrera de nutrición. Consta de 6 prácticas de laboratorio: operaciones básicas de laboratorio, cambios de la materia, estequimetría, soluciones, cinética química y medida de pH.
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Cordova, Yamahuchi Leslie. "Química General (MA212): Guía de Prácticas de Laboratorio, ciclo 2014-1." Universidad Peruana de Ciencias Aplicadas - UPC, 2014. http://hdl.handle.net/10757/313670.
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Guía de laboratorio del curso Química General (MA212) para la carrera de nutrición. Consta de 6 prácticas de laboratorio: operaciones básicas de laboratorio, cambios de la materia, estequimetría, soluciones, cinética química y medida de pH.
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Robles, Valcarcel Pamela, and Yamauchi Leslie Córdova. "Química Orgánica (MA129): Guía de laboratorio, ciclo 2014-1." Universidad Peruana de Ciencias Aplicadas - UPC, 2014. http://hdl.handle.net/10757/313688.
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Guía de prácticas de laboratorio del Curso Química Orgánica (MA129) para la carrera de Nutrición y Dietética, que corresponde al ciclo 2014-1. Contenido: Normas de bioseguridad en el laboratorio -- Laboratorio N° 1: Caracterización de compuestos covalentes e iónicos -- Laboratorio N° 2: Compuestos orgánicos oxigenados -- Laboratorio N° 3 : Saponificación
Laboratorio N° 4: Reconocimiento de carbohidratos -- Laboratorio Nº 5: Reconocimiento de proteínas -- Laboratorio N° 6: Reconocimiento de lípidos.
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Pérez, Zenteno Betty, and Astete Ana María Montalvo. "Química General y Orgánica CCSS (MA226): Guía de Prácticas de Laboratorio, ciclo 2013-2." Universidad Peruana de Ciencias Aplicadas - UPC, 2013. http://hdl.handle.net/10757/296666.
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Pérez, Zenteno Betty, and Astete Ana María Montalvo. "Química General y Orgánica CCSS (MA226): Guía de Prácticas de Laboratorio, ciclo 2014-1." Universidad Peruana de Ciencias Aplicadas - UPC, 2014. http://hdl.handle.net/10757/313669.
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Montalvo, Astete Ana María, and Zenteno Betty Perez. "Química General y Orgánica CCSS (MA226): Guía de Prácticas de Laboratorio, ciclo 2014-2." Universidad Peruana de Ciencias Aplicadas - UPC, 2014. http://hdl.handle.net/10757/324001.
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Bustamante, Luna Elena, Yamauchi Leslie Córdova, Astete Ana María Montalvo, and Zenteno Betty Pérez. "Guía de Prácticas de Química (MA41), ciclo 2013-1." Universidad Peruana de Ciencias Aplicadas - UPC, 2013. http://hdl.handle.net/10757/273152.
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Guía de experimentos de Laboratorio para el curso de Química, que corresponde al ciclo 2013-1. En este curso se imparte los conocimientos básicos y fundamentales de Química necesarios para todos los alumnos que siguen una carrera de Ingeniería.
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Córdova, Yamauchi Leslie, Zenteno Betty Pérez, Astete Ana María Montalvo, and Luna Elena Bustamante. "Guía de Prácticas de Química (MA41), ciclo 2013-2." Universidad Peruana de Ciencias Aplicadas - UPC, 2013. http://hdl.handle.net/10757/297029.
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Guía de experimentos de Laboratorio para el curso de Química, que corresponde al ciclo 2013-2. En este curso se imparte los conocimientos básicos y fundamentales de Química necesarios para todos los alumnos que siguen una carrera de Ingeniería.
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Cordova, Yamahuchi Leslie, Zenteno Betty Perez, Astete Ana María Montalvo, and Luna Elena Bustamante. "Guía de Prácticas de Química (MA41), ciclo 2014-1." Universidad Peruana de Ciencias Aplicadas - UPC, 2014. http://hdl.handle.net/10757/313710.
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Guía de experimentos de Laboratorio para el curso de Química, que corresponde al ciclo 2014-1. En este curso se imparte los conocimientos básicos y fundamentales de Química necesarios para todos los alumnos que siguen una carrera de Ingeniería.
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Cordova, Yamahuchi Leslie, Luna Elena Bustamante, Astete Ana María Montalvo, and Zenteno Betty Pérez. "Guía de Prácticas de Química (MA41), ciclo 2014-2." Universidad Peruana de Ciencias Aplicadas - UPC, 2014. http://hdl.handle.net/10757/324022.
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Cieza, Dávila Javier. "Introducción a la electrónica y las telecomunicaciones: material de trabajo para el laboratorio 2009-1." Universidad Peruana de Ciencias Aplicadas - UPC, 2009. http://hdl.handle.net/10757/272738.
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Moyano, Ivanna Carolina. "Diseño de manual de calidad para el aseguramiento de la calidad analítica en laboratorio enológico según la Norma ISO 17025:2005." Bachelor's thesis, Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias, 2017. http://bdigital.uncu.edu.ar/8753.
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Este trabajo se realiza con el objetivo de documentar y estructurar, el material obligatorio que debe tener el Laboratorio de la Bodega RosAr, según los lineamientos de la Norma ISO 17025. Se actualizan y se crean técnicas, procedimientos, instructivos y registros que sirven como soporte para la ejecución de los ensayos y garantizar el aseguramiento del control de calidad de datos, esto se realiza en base a la Norma ISO 17025 que contiene todos los requisitos que tienen que cumplir los laboratorios de ensayo y calibración si desean demostrar que poseen un Sistema de Gestión. El propósito del diseño del Manual de Calidad en el Laboratorio de la Bodega RosAr, para otorgar un orden además de poder ofrecer un mejor servicio a la bodega y calidad en todos sus procesos al entregar resultados confiables.
Además se documenta un procedimiento fundamental para el cálculo de incertidumbre, el cual genera confiabilidad y calidad de los resultados.
Este trabajo se inicia con la revisión de documentos existentes en el laboratorio, con el fin de establecer cuáles deberían modificarse y cuales deberían crearse, en base a los requerimientos de la Norma ISO 17025.
Contar con un Sistema de Gestión documentado en el Manual de Calidad, siguiendo con los lineamientos de la Norma 17025:2005 en el laboratorio, favorecerá el Sistema de Gestión de Calidad general de la bodega.Fil: Moyano, Ivanna Carolina. Universidad Nacional de Cuyo. Facultad de Ciencias Agrarias.
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Aguilera, Aravena Alvaro Rodrigo, and Silva Juvenal Alejandro León. "Manual de calidad y manual de procedimientos generales para la acreditación del Laboratorio de Química de Alimentos y Materias Grasas." Tesis, Universidad de Chile, 2004. http://repositorio.uchile.cl/handle/2250/105402.
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Memoria para optar al título de Ingeniero en AlimentosNo autorizada por el autor para ser publicada a texto completo en el Portal de Tesis Electrónicas
La presente memoria titulada “Manual de Calidad y Manual de Procedimientos Generales para la Acreditación del Laboratorio de Química de Alimentos y Materias Grasas”, tuvo como objetivo elaborar el “Manual de Calidad” y el “Manual de Procedimientos Generales” para el Laboratorio de Química de Alimentos y Materias Grasas. Esto obedece a la creciente demanda de clientes que requieren de los servicios de análisis químicos de alimentos que sean confiables. Para ello se realizó una exhaustiva revisión de la normativa vigente en Chile, que incluyó a NCh-ISO 17025.Of2001 “Requisitos generales para la competencia de los laboratorios de ensayo y calibración”, indispensable para la acreditación del laboratorio. En lo que respecta a Sistema de Gestión de la Calidad, se consideró de interés actualizarlo de acuerdo a NCh-ISO 9001.Of2001 “Sistemas de gestión de la calidad- Requisitos”, utilizando la terminología de la norma NCh-ISO 9000.Of2001 “Sistemas de gestión de calidad – Fundamentos y vocabulario”. Del estudio de las normas mencionadas, de Acreditación y de Sistemas de Gestión de la Calidad, emanaron recomendaciones para desarrollar e implementar un Sistema de Gestión de la Calidad en el Laboratorio de Química de Alimentos y Materias Grasas. Además se incluyen recomendaciones que permitan demostrar la competencia del laboratorio para producir datos técnicamente válidos. En forma anexa a la memoria se incorporan el “Manual de Calidad” y el “Manual de Procedimientos Generales” del Laboratorio de Química de Alimentos y Materias Grasas
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Velásquez, Pomar Jorge Humberto, Lúcar Christian Alegre, Montreuil Iturri Carolina De, Vereau Pierre Chávez, Meléndez Miguel Marzal, Melgar Yáñez Rosa Núñez, Arredondo Adriana Paredes, Vargas July Ana Yovera, and Arruda Chaves Erika De. "Inmunología, Microbiología y Enfermedades Infecciosas (ME17), ciclo 2014-1." Universidad Peruana de Ciencias Aplicadas - UPC, 2014. http://hdl.handle.net/10757/313690.
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Cuaderno de trabajo del Curso de Inmunología, Microbiología y Enfermedades Infecciosas (ME17)de la Escuela de Medicina, que corresponde al ciclo 2014-1. Contenido: microbiología básica, inmunología básica y relación hospedero-parásito, enfermedades infecciosas oculares, óticas y del aparato respiratorio, enfermedades infecciosas del sistema nervioso.
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Lux, Melissa McNeil. "A laboratory course in experimental genetics for the biology major." Thesis, University of North Texas, 2001. https://digital.library.unt.edu/ark:/67531/metadc3007/.
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This manual has been designed for a class of twenty- four students concurrently enrolled in the lecture course. The laboratory aids in the learning process and fosters an interest in the science of genetics. This manual and the experiments contained within are both informative and fun. The manual correlates with and expands upon the genetics course. Each investigation, with the exception of the Drosophila melanogaster project, can be completed in a 3-4 hour timeframe. This manual provides a “hands on” experience of theories simply discussed in the lecture course. This manual is intended to be a one-source manual where each investigation is designed to include an adequate introduction. Special attention has been given for each investigation with both the student and instructor in mind.
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Brito-Rodriquez, Carmen Lydia. "Advanced Molecular and Microbial Techniques: a Complete Laboratory Notebook." Thesis, University of North Texas, 1998. https://digital.library.unt.edu/ark:/67531/metadc278293/.
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The purpose of this project is to produce a complete and thorough notebook that may be used to supplement laboratory coursework. Its intent is to be used primarily by the students to aid them in understanding background information and the proper laboratory procedures involved in various types of experiments. The laboratory notebook is a summation of all the experiments and procedures used in the six-credit hour Advanced Microbial and Molecular Biology (BIOL 5160) course offered during the summer semester at the University of North Texas. This class is a team taught effort by Professors O'Donovan and Kunz. The course is constructed as an intensive practice exercise to teach the student about gene mutations, biosynthetic pathways, preparation and analysis of plasmid DNA, and many other topics included in the notebook.
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Peters, Carolyn J. Rhodes Dent. "An assessment template for introductory college biological laboratory manuals." Normal, Ill. : Illinois State University, 2006. http://proquest.umi.com/pqdweb?index=0&did=1225152531&SrchMode=1&sid=1&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1178116677&clientId=43838.
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Thesis (Ed. D.)--Illinois State University, 2006.Title from title page screen, viewed on May 2, 2007. Dissertation Committee: Dent Rhodes (chair), Nada Chang, Kenneth Jerich, Marilyn Morey. Includes bibliographical references (leaves 107-113) and abstract. Also available in print.
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Mabie, Kevin T. "Solar simulation laboratory description and manual." Thesis, Monterey, California. Naval Postgraduate School, 1985. http://hdl.handle.net/10945/21549.
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Strong, Ramey. ""Remodeling" the Hadwiger Communication Laboratory : the lab manager manual and lab assistant training program /." View online, 2009. http://repository.eiu.edu/theses/docs/32211131592053.pdf.
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Lopes, Diana Espada. "O papel do médico veterinário em biossegurança laboratorial : desenvolvimento de um manual de biossegurança para o Laboratório de Bromatologia e Defesa Biológica do Exército Português." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2019. http://hdl.handle.net/10400.5/17688.
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Dissertação de Mestrado Integrado em Medicina VeterináriaA biossegurança deve ser uma das prioridades dos Estados na defesa e proteção dos seus cidadãos. Os surtos epidémicos ou a ameaça do bioterrorismo exigem de governos e instituições internacionais estratégias adequadas de combate a tais riscos. Atendendo ao facto de, presentemente em Portugal, não existir legislação sobre biossegurança laboratorial suficientemente abrangente, peça-chave nesse tipo de estratégias, a presente dissertação foi elaborada com o intuito de fundamentar o desenho e conceção de um manual de biossegurança laboratorial e de o produzir para utilização no Laboratório de Bromatologia e Defesa Biológica do Exército Português. A dissertação começa por discutir a distinção conceptual entre biossegurança e bioproteção. Procede seguidamente ao seu enquadramento na perspetiva de diferentes organizações e discute a sua importância no âmbito da saúde pública. Após a identificação dos desafios atuais em biossegurança, analisam-se as respostas que têm sido dadas aos riscos a nível mundial, europeu e português, em particular no que toca ao quadro normativo, regulamentar e das convenções entre países. No contexto português, para além da abordagem à legislação atual e à nova norma de biossegurança, também foi feita referência ao projeto UPCAST e à Rede Laboratorial Portuguesa de Biossegurança. Como parte integrante da dissertação segue-se a apresentação do manual, que incide sobre infraestruturas, equipamento laboratorial, equipamento de proteção individual, manuseamento e eliminação de resíduos, boas práticas laboratoriais, entre outros. Por fim, é feita uma discussão crítica das questões que foram sendo levantadas ao longo da fundamentação do manual, procurando contextualizá-las em relação aos propósitos da dissertação e às linhas orientadoras que estruturaram o seu desenho e conceção.
ABSTRACT - The Role of the Veterinary Professional in Laboratory Biosafety and Biosecurity: Development of a Biosafety and Biosecurity Manual to the Bromatology and Biological Defence Laboratory of the Portuguese Army - Biosecurity and biosafety should be a priority of all States in the defence and protection of their citizens. Epidemic outbreaks or the threat of bioterrorism demand from Governments and international institutions appropriate strategic measures to fight such risks. In view of the fact that, currently in Portugal, there is a lack of broader laboratory biosafety and biosecurity legislation, which is a key part of this type of strategy, this thesis was elaborated in order to provide the conceptual framework for the design and conception of a biosafety and biosecurity manual and to produce it for use at the Laboratory of Bromatology and Biological Defence of the Portuguese Army. The thesis begins by discussing the conceptual distinction between biosafety and biosecurity. It then proceeds to examine those concepts in the perspective of different organisations and considers its importance in the field of public health. Following the identification of the current challenges in biosafety and biosecurity, an analyses of the responses that have been given to these risks at a global, European and Portuguese levels is done, in particular related to the regulatory framework, norms and conventions between countries. In the Portuguese context, in addition to the approach to the current legislation and the new biosafety standard, were also considered the UPCAST project and the Portuguese Biosafety Laboratory Network. The thesis includes the presentation of the manual, which focuses on infrastructure, laboratory equipment, personal protective equipment, waste handling and disposal, good laboratory practices, among others. Finally, a critical discussion is made of the issues emerged from the discussion of the conceptual framework, seeking to contextualize them in relation to the purposes of the thesis and the guidelines that structured the design and conception of the manual.
N/A
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Bendezú, Jorge, Ricardo Choque, Manolo Fernández, Miguel Marzal, Sandra Morales, Ricardo Montesinos, Adriana Paredes, and Aldo Rojas. "Manual de laboratorio para cultivo de hibridomas. Obtención y purificación de anticuerpos monoclonales." Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/626436.
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Esta publicación busca presentar las metodologías utilizadas para la obtención de anticuerpos monoclonales, desde el cultivo celular de líneas llamadas hibridomas, mediante la criopreservación, la adaptación a distintos medios de cultivo, la amplificación celular, la cosecha de anticuerpos monoclonales y la criopreservación.
Asimismo, este libro explica las técnicas empleadas para el proceso de purificación como son la evaluación del punto de producción de anticuerpos, la purificación de los anticuerpos empleando resinas y sistemas de cromatografia, la desalinización y la obtención de niveles de pureza aceptables.
Se especifica que el objetivo central es emplear dichos anticuerpos en el desarrollo de futuros procedimientos de diagnóstico como ensayos de ELISA y desarrollo de prototipos de pruebas inmunocromatográficas. Los anticuerpos monoclonales desarrollados fueron dirigidos contra una proteína del virus de la laringotraqueitis infecciosa aviar el cual es un patógeno que tiene un impacto sobre la producción avícola mundial.
Esta investigación desarrolla los métodos empleados por la empresa FARVET en el marco de un proyecto de investigación cofinanciado por el Instituto Nacional de Innovación Agraria (INIA).
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Lawrence, Paula Tracki. "Developing a Laboratory Curriculum for Physics I." UNF Digital Commons, 1986. http://digitalcommons.unf.edu/etd/58.
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This curriculum project reviews the current research on laboratory activity formats and their effectiveness. The literature concerning laboratory safety and teacher liability is also reviewed. The revision of Florida state high school science requirements is presented and the curriculum developed corresponds to these revisions. The project includes laboratory activities that correspond to the course student performance standards as designated by the state of Florida for the Physics I course and strives to aid teachers in fulfilling the 72 hour laboratory time requirement to meet eligibility requirements for additional state funding. The criteria for selecting activities and materials are also included in this project. A sample evaluation form is included, as well as a summary of these teacher evaluations of the developed curriculum.
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Ortiz, Gil Elizabeth. "Elaboración de un manual de procedimientos para la elaboración de expedientes para contrataciones estatales para la empresa Laboratorios del Sur S.A." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2013. http://hdl.handle.net/10757/306169.
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El tema que aborda el presente proyecto gira en torno a la necesidad de la empresa Laboratorios del Sur S.A. de contar con un manual de procedimientos para la elaboración de expedientes para contrataciones estatales.
Mediante el proyecto se comprueba que la elaboración de un manual de procedimientos para la elaboración de expedientes para contrataciones estatales permite generar expedientes que contienen propuestas técnicas y económicas que cumplen adecuadamente con los parámetros de evaluación de las instituciones estatales, lo cual, permite una mejora en la productividad del área de ventas de la empresa Laboratorios del Sur impactando positivamente en los resultados económicos de la misma.
Este trabajo esta divido en cuatro capítulos. En el primero, se describen los conceptos relacionados a las contrataciones estatales y los procesos de contrataciones estatales a nivel mundial y en Perú, así como los organismos encargados de realizar el control de los mismos en los distintos países. En el segundo, se evalúa y analiza el desempeño de la empresa Laboratorios del Sur SA en relación a la elaboración de los expedientes para los procesos de contrataciones estatales. En el tercer capítulo se establece la propuesta de mejora para la empresa. Y finalmente, en el cuarto capítulo se detalla el impacto económico de la aplicación del manual para la empresa Laboratorios del Sur S.A y otros beneficios no económicos relacionados a su implementación.
De este modo, se llega a la conclusión de que el presente proyecto genera beneficios muy importantes que no pueden ser desaprovechados por la empresa.
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Franco, Cirene Aparecida. "Acupuntura manual no Baihui (VG20) melhora o aprendizado e a memória em camundongos." reponame:Repositório Institucional da UFSC, 2013. https://repositorio.ufsc.br/handle/123456789/107289.
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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2013.Made available in DSpace on 2013-12-05T23:43:04Z (GMT). No. of bitstreams: 1 321479.pdf: 1106883 bytes, checksum: 0e282f72046d3410ea8da158af487ca3 (MD5) Previous issue date: 2013
Por muitos anos, a memória tem fascinado os filósofos, psicólogos e neurocientistas. No entanto, não está totalmente claro se é possível obter melhora da memória. Sabe-se que a acupuntura é uma terapia bem aceita no mundo e que suas intervenções milenares e contemporâneas exercem grande influência sobre doenças neurológicas. Estudos descritos na literatura mostram que a acupuntura no acuponto Baihui (VG20) diminuiu os danos causados por acidente vascular cerebral ou isquemia cerebral, além de exercer efeitos positivos na reabilitação neurofuncional e tratar condições como cefaléias, tonturas e ansiedade tanto em humanos quanto em modelos animais. Sendo assim, o presente estudo procurou investigar se a acupuntura manual (AM) no Baihui (VG20) seria capaz de melhorar o aprendizado e a memória em camundongos. Os animais foram tratados com AM por um período mínimo de 15 dias e submetidos a testes de comportamento para avaliação da memória, da ansiedade, da depressão e da dor. O tratamento com AM neste acuponto promoveu significativa melhora da memória de curta e de longa duração, tanto no teste de reconhecimento de objetos quanto da esquiva inibitória, quando comparado aos grupos controle e sham. Além disto, a AM no Baihui (VG20) aumentou de forma significativa as escolhas corretas no sexto, sétimo e oitavo dias no labirinto radial de oito braços e reduziu o total de erros no sétimo e no oitavo dias quando comparada aos grupos controle e sham. Por outro lado, a AM no Baihui (VG20) não apresentou atividade ansiolítica quando analisada no teste da caixa claro/escuro e no labirinto em cruz elevado. No entanto, promoveu significativa atividade antidepressiva no teste da suspensão da cauda quando comparada aos grupos controle e sham. No teste da formalina, a AM mostrou um efeito antinociceptivo relacionado com a dor neurogênica, mas não com a dor inflamatória. Assim, os dados do presente estudo demonstram que a estimulação do acuponto Baihui (VG20) pela AM induz melhora da aprendizagem e da memória, além de ter importante atividade antidepressiva em camundongos.
Abstract : For many years, memory has fascinated the philosophers, psychologists, and neurobiologists. However, is not clear whether it is possible to obtain improved memory. It is known that acupuncture therapy is well-accepted in the world and its ancient and contemporary interventions exert a strong influence on brain-related pathologies. Previous studies show that acupuncture at acupoint Baihui (GV20) decreased the damage caused by stroke or cerebral ischemia as well as positive effects on neurofunctional rehabilitation and treat conditions such as headaches, dizziness and anxiety in both humans and in animal models. Thus, this study aimed to investigate whether manual acupuncture (MA) in Baihui (VG20) could improve learning and memory in mice. The animals were treated with MA for a minimum of 15 days and subjected to behavioral tests for evaluation of memory, anxiety, depression and pain.Treatment with MA in Baihui (VG20) caused a significant improvement in short and long-term memory in both the test object recognition as inhibitory avoidance when compared with the control and sham groups. In addition, the MA in Baihui (VG20) significantly increased the correct choices in the sixth, seventh and eighth days in eight-arm radial maze and reduced the total errors in the seventh and eighth days compared with the control and sham groups. On the other hand, the MA in Baihui (VG20) showed no anxiolytic activity when analyzed in the test box light/dark and elevated plus maze. However, it was able to promote significant antidepressant activity in the tail suspension test compared with the control and sham groups. In the formalin test, MA showed an antinociceptive effect associated with neurogenic pain, but not in inflammatory pain. Thus, the data from this study demonstrate that stimulation of the acupoint Baihui (VG20) by manual acupuncture induces improvement of learning and memory as well as having important antidepressant activity in mice.
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James, Jonathan Peter. "Field and laboratory analyses of manual tasks in the South African automotive industry." Thesis, Rhodes University, 2007. http://hdl.handle.net/10962/d1005199.
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The present study adopted a “field-laboratory-field” approach in the assessment of the efficacy of ergonomics interventions specific to two selected tasks evaluated in a South African automotive industry. Initial field testing was conducted in an Eastern Cape (South Africa) automotive plant where high risk areas were identified during walkthrough ergonomics surveys in conjunction with interaction with operators. Temporal factors and working postures of 12 industrial workers were recorded and observed, while physiological and perceptual responses were assessed. Two priority areas were focused upon for analysis, namely the Paintshop and Bodyshop with the former identified as being the more taxing of the two tasks. Responses of 30 students participating in rigourously controlled laboratory simulations were subsequently collected while completing the two tasks, namely the Paintshop Trolley Transfer (PTT) and Car Door Carriage (CDC) for participants. Working postures, kinematic, physiological and perceptual responses were assessed pre- and post-intervention. Following the laboratory experimentation a basic re-evaluation was conducted at the plant to assess whether the proposed changes had a positive effect on working postures, physiological and perceptual responses. The results of the preliminary field investigation revealed a prevalence of awkward working postures and excessive manual work in both areas. Laboratory experimentation revealed a notable reduction in task demands pre- versus post-intervention. The PTT mean lean angle for two-handed pre-intervention pulling observations of 23.7° (±3.51) was reduced to 13.9° (±2.21) post-intervention. Low back disorder (LBD) risk was reduced during the two-handed pull intervention (from 36.8% ±8.03 to 21.7% ±5.31). A significant decrement in heart rate responses from 103 bt.min-1 (±11.62) to 93 bt.min[superscript -1] (±11.77) was recorded during the two-handed symmetrical pushing intervention. The electromyography (EMG) responses for one-handed pushing and pulling pre-intervention showed the highest levels of muscular activity in the right medial deltoid due to an awkward and asymmetrical posture. CDC responses demonstrated that minor changes in the storage height of the door resulted in a significant reduction in sagittal flexion from 28.0° (±4.78) to 20.7° (±5.65). Predictions of average probability of LBD risk were significantly reduced from 50.3% (±5.91) to 39.8% (±5.10) for post-intervention car door lifting. In addition, the greatest reduction in EMG activity as a %MVC was achieved during sub-task ii (reduced from 35.1 to 13.7% and 30.5 to 13.9% for left and right erector spinae respectively) which was associated with the introduction of the transfer trolley for the door transfer phase of the CDC. Re-evaluation in the automotive plant revealed that the most notable change has been the implementation of automated ride on trolleys in the Paintshop. The Bodyshop area has also been modified to allow more effective job rotation and the step into the storage bin has been reduced via a “low-cost” stepping platform. Mean heart rate recordings were reduced from 94 (±9.77) bt.min[superscript -1] to 81 (±3.72) bt.min[superscript -1] in the Paintshop. Overall the results demonstrate the effect of “low-cost” interventions in reducing the physical stresses placed on workers in the automotive industry where much of the work is still done manually.
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Flores, Arévalo Paulo Roberto. "Integración de gestión en salud y seguridad ocupacional con el manual de bioseguridad de la Organización Mundial de la Salud para laboratorios acreditados con ISO/IEC 17025." Master's thesis, Universidad Nacional Mayor de San Marcos, 2020. https://hdl.handle.net/20.500.12672/11603.
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Desarrolla un sistema de gestión que integre la seguridad, la salud ocupacional y la bioseguridad para los laboratorios de ensayo. Se seleccionó un laboratorio acreditado de ensayos en microbiología, para trabajar con el personal que labora en él, se realizaron encuestas y evaluaciones para recolectar datos y elaborar una matriz para identificación de peligros, evaluación del riesgo y establecimiento de medidas de control (IPERC), lo cual permitió elaborar el mapa de riesgos y el manual integrado de gestión en seguridad, salud ocupacional y bioseguridad, donde se describen todos los procesos asociados a riesgos en el laboratorio y áreas conexas (oficinas, almacenes y áreas de apoyo) y se proponen las medidas de control a adoptar. Asimismo, se establece un conjunto de indicadores de gestión para evaluar el desempeño del sistema implementado y proponer su mejora continua. Se identificaron los riesgos inherentes asociados a las actividades del laboratorio, de los cuales dieciséis son des nivel alto a extremo. Se implementaron medidas de control para reducirlos a un nivel de tolerable a moderado y se registraron en un manual integrado de gestión. Se brindó capacitación al personal en los temas materia de la implementación para garantizar la disminución de riesgos, la capacitación fue satisfactoria y fue evaluada en el tiempo y se verificó su eficacia. Se logró la implementación satisfactoria de un sistema de gestión en seguridad, salud ocupacional y bioseguridad en el laboratorio de microbiología acreditado para evitar, prevenir y actuar eficazmente frente a posibles riesgos.Tesis
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Alharbi, Najwa. "The Effectiveness of Hybrid Problem-Based Learning versus Manual-Based Learning in the Microbiology Laboratory." Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc984143/.
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Promising results from the use of problem-based learning (PBL) as a teaching method in medical programs have encouraged many institutions to incorporate PBL into their curricula. This study investigates how applying hybrid-PBL (H-PBL) in a microbiology laboratory impacts students' higher-order thinking as compared to applying a lecture-based pedagogy. The experimental design compared the learning outcomes of two groups of students: the control group and the H-PBL group, for whom PBL cases comprised 30% of the curriculum. Both groups were taught basic skills for the microbiology lab by the same instructor. Using the traditional teaching style for the control group, the instructor offered each student what they needed for their experiments. The H-PBL group practiced experimental design, data analysis, theory proposal, and created research questions by using six study cases that were closely linked to the area of study. The outcome was measured using a pre- and post- assessment consisting of 24 questions that was designed by following Bloom's taxonomy of learning levels. A one-way ANOVA was used to analyze the data. The results showed that for the first three levels of Bloom's taxonomy— knowledge, comprehension, and application—there were no statistically significant differences between the H-PBL and control group gain scores as determined by a one-way ANOVA. For the knowledge level, f (1, 78) = .232, and p = .632; for the comprehension level, f (1, 78) = .004, and p = .951; and for the application level f (1, 78) =. 028, and p =.863. On the other hand, the gain scores for the three higher levels—analysis, evaluation, and creativity—improved for the H-PBL group. The analysis level showed statistically significant differences, with f (1, 78) = 4.012, and p = .049. Also, there were statistically significant differences in students' performance at the evaluation level, with f (1, 78) = 11.495, and p = .001, and the creativity level, with f (1,78 ) = 23.432, and p = .000. In conclusion, the study results supported the value of incorporating hybrid problem-based learning (H-PBL) into the traditional microbiology laboratory curriculum.
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Zárate, Mulia Josué. "Propuesta de un manual de procedimientos para el laboratorio de digitalización en la Dirección de Infraestructura Académica de la UAEM." Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2020. http://hdl.handle.net/20.500.11799/110309.
Full textAbstract:
El presente trabajo tiene como objetivo elaborar un manual de procedimientos para el laboratorio de digitalización en la Dirección de Infraestructura Académica de la Universidad Autónoma del Estado de México con conceptos, procesos y elementos profesionales de la licenciatura en Ciencias de la Información Documental.
Para poder elaborar adecuadamente un manual de procedimientos se debe conocer cómo se hace, no es simplificar solamente con la teoría, sino también con la experiencia técnica y profesional, esto para proponer resultados con valor agregado o innovador. Analizaremos qué es un manual de procedimientos, la importancia, la relevancia, así como el impacto del manual que tiene dentro de toda organización o institución.
Elaborar un manual de procedimientos estandarizado implica partir desde la conceptualización, es decir, cómo y en dónde se desarrolla, el porqué es importante qué cada área departamental identifique y conozca el manual de procedimientos.
Esta propuesta del manual de procedimientos es de carácter profesional y técnico, los lineamientos presentados son con base en la experiencia profesional y con las normas internas de la Universidad Autónoma del Estado de México.
La propuesta a desarrollar es procedente del surgimiento departamental del laboratorio de digitalización en la Biblioteca Central, para dar cumplimiento a los objetivos institucionales y académicos de la Universidad.
Los elementos aplicados a este manual coadyuvan principalmente a las nuevas tendencias tecnológicas, como es la preservación, conservación, almacenamiento, el acceso, la búsqueda, la difusión del material bibliográfico (histórico) a través de la digitalización y la interconexión de la Web.
Para que este departamento tenga un lugar orgánico dentro de la Dirección de Infraestructura Académica, es importante contar con un manual de procedimientos.
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Marshall, Katherine C. "An Evaluation of the Water Lifting Limit of a Manually Operated Suction Pump: Model Estimation and Laboratory Assessment." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/7056.
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With 663 million people still without access to an improved drinking water source, there is no room for complacency in the pursuit of Sustainable Development Goal (SDG) Target 6.1: “universal and equitable access to safe and affordable drinking water for all” by 2030 (WHO, 2017). All of the current efforts related to water supply service delivery will require continued enthusiasm in diligent implementation and thoughtful evaluation. This cannot be over-emphasized in relation to rural inhabitants of low-income countries (LICs), as they represent the largest percentage of those still reliant on unimproved drinking water sources. In that lies the motivation and value of this thesis research- improving water supply service delivery in LICs.
Manually operated suction pumps, being relatively robust, low cost, and feasible to manufacture locally, are an important technology in providing access to improved drinking water sources in LICs, especially in the context of Self-supply. It seems widely accepted that the water-lifting limit of suction pumps as reported in practice is approximately seven meters. However, some observations by our research group of manually operated suction pumps lifting water upwards of nine meters brought this “general rule of thumb” limit into question. Therefore, a focused investigation on the capabilities of a manually operated suction pump (a Pitcher Pump) was conducted in an attempt to address these discrepancies, and in so doing, contribute to the understanding of this technology with the intent of providing results with practical relevance to its potential; that is, provide evidence that can inform the use of these pumps for water supply.
In this research, a simple model based on commonly used engineering approaches employing empirical equations to describe head loss in a pump system was used to estimate the suction lift limit under presumed system parameters. Fundamentally based on the energy equation applied to incompressible flow in pipes, the empirically derived Darcy-Weisbach equation and Hydraulic Institute Standards acceleration head equation were used to estimate frictional and acceleration head losses. Considering the theoretical maximum suction lift is limited to the height of a column of water that would be supported by atmospheric pressure, reduced only by the vapor pressure of water, subtracting from this the model was used to predict the suction lift limit, also referred to herein as the practical theoretical limit, assuming a low (4 L/min) and high (11 L/min) flow rate for three systems: 1) one using 1.25-inch internal diameter GI pipes, 2) one using 1.25-inch internal diameter PVC pipes, and 3) one using 2-inch internal diameter PVC pipes. In all considered cases, with an elevation equal to sea level, the suction lift limit was estimated to be over nine meters. At a minimum, the suction lift limit was estimated to be approximately 9.4 meters for systems using 1.25-inch internal diameter pipe and 9.8 meters for systems using 2-inch internal diameter pipe, with essentially no discernable effects noticed between pipe material or pipe age. Additionally, laboratory (field) trials using a Simmons Manufacturing Picher Pump and each of the aforementioned pipe specifications were conducted at the University of South Florida (Tampa, FL, USA) to determine the practical pumping limit for these systems. Results from the pumping trials indicated that the practical pumping limit- the greatest height at which a reasonable pumping rate could be consistently sustained with only modest effort, as perceived by the person pumping- for a Pitcher Pump is around nine meters (9 meters when using 1.25-inch internal diameter GI or PVC pipe and 9.4 meters when using 2-inch internal diameter PVC pipe). Therefore, results from this research present two pieces of evidence which suggest that the practical water-lifting limit of manually operated suction pumps is somewhere around nine meters (at sea level), implying that reconsideration of the seven-meter suction lift limit commonly reported in the field might be warranted.
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Debolt, Adam Michael. "Alcon LADARVision® 4000: A Manual on Refurbishing the Laser for Use in a Laboratory Environment." Thesis, The University of Arizona, 2013. http://hdl.handle.net/10150/297536.
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The LADARVision® 4000 excimer laser was designed and manufactured by Alcon for LASIK surgery procedures. Our lab has repurposed such a laser system for use in an academic, laboratory setting. The ultraviolet (UV) laser beam produced by the system can be used as an ionizer for atom beam detection in atom optics experiments such as atom interferometry. The goal of this project is to build a detector for atoms with higher ionization potentials than those we have detected in past atom interferometry experiments at the University of Arizona. The availability of used LADARVision® 4000 systems has prompted the creation of this manual, which outlines the procedures we used for refurbishing the laser system and the procedures for operating the refurbished system. These details are separated into three main sections: Electrical Systems, Gas Systems, and Software.
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Jimenez, Limay Paula Alexandra, and León Alvaro Noé Huamán. "Diseño de un manual de calidad y procedimiento para la implementación del sistema de gestión de calidad ISO 9001:2008 en laboratorio de fármacos veterinarios." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2015. https://hdl.handle.net/20.500.12672/3908.
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Durante los últimos años hemos evidenciado la importancia de conducir las organizaciones en base a un sistema de gestión de calidad que permita definir la interacción y establezca los controles de cada uno de sus procesos involucrados, la búsqueda de la satisfacción del cliente y difundir la búsqueda de la mejora continua, que le permita adaptarse rápidamente en un mercado que cambia constantemente. El objetivo de realizar este análisis prospectivodescriptivo es diseñar un manual de calidad y procedimientos que permitan estandarizar la documentación de todos los procesos en una organización, en base a una norma internacional certificable como es el caso de la ISO 9001:2008. Es por este motivo que la norma en mención exige, para mantener un sistema de gestión de calidad, un procedimiento que dé las directivas para el control de documentos que sirvan de medio de difusión sobre las actividades que se realizan en cada proceso dentro de la organización, un procedimiento que dé las directivas para el control de los registros generados en cada actividad de la organización, un procedimiento que explique el tratamiento que se le da a cada producto que esté fuera de sus especificaciones, un procedimiento que explique el tratamiento que se le dará a cualquier no conformidad o potencial no conformidad respecto con la norma en mención o a la documentación generada en el sistema y, un procedimiento que de los lineamientos para auditar el sistema de gestión de calidad con la finalidad de comprobar su eficacia y mejora continua. De igual manera, mostrar la importancia de contar con un Manual de Calidad que permita comunicar a la organización la política y objetivos de calidad que la alta dirección desea difundir a cada uno de los colaboradores, los procesos que forman parte del alcance del sistema y de la interacción de cada uno de ellos, además de la mención de los procedimientos complementarios que la organización ha decidido implementar.--- Over the past years has shown the importance of organizations leads to a quality management system to define the interaction and set controls for each process involved, looking for customer satisfaction and promote the pursuit of continuous improvement, enabling it to adapt quickly in a market which is constantly changing. The aim of this analysis prospective-descriptive is to design a quality manual and procedures which allows standardize documentation for all process in an organization, based on a Certifiable International Standard as ISO 9001:2008. For this reason the norm requires to maintain a quality management system. The norm requires a procedure which gives directives for the control of documents to serve as a means of diffusion on activities that take place in every process within the Organization, also requires to include a procedure that gives directives for the control of records generated in each activity of the Organization, call for a procedure that explain the treatment given to each product that is out of its specifications, requires a procedure that explains the treatment that is given to any non-conformance or potential non- conformance in regards or documentation generated by the system and, call for a procedure to give guidelines to audit the quality management systems in order to check effectiveness and continuous improvement. Similarly, show the importance of having a Quality Manual that allows communicate to the Organization, the quality policy and objectives which was established by the senior management and communicated to each one of the partners, and the processes that are part of the scope of the system and the interaction of each of them, besides the mention of complementary procedures that the Organization has decided to implement. Keywords: System, procedures, manual, processes.
Tesis
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Díaz, Caruti Leonardo Rodrigo. "Elaboración de un manual de calidad para el departamento de operaciones de calidad de Pfizer Chile S. A." Tesis, Universidad de Chile, 2004. http://repositorio.uchile.cl/handle/2250/105395.
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Moreland, Amy L. "General Biology Lecture and Laboratory Curriculum Outline in a Two or Four-Year College." Thesis, University of North Texas, 2000. https://digital.library.unt.edu/ark:/67531/metadc2559/.
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In July of 1999, I wrote to 24 Texas junior and community colleges (and one four-year institution) describing my thesis agenda of a general biology lecture and laboratory syllabus for introductory biology students. I requested the titles and authors of the general biology textbooks and laboratory manuals they were currently using, the publishers of these texts, and the edition of said texts. I then contacted publishers of the various textbooks who, in turn, directed me to the Dallas-area representatives for further inquiries. I assimilated the various authors' general biology topics into a two-semester syllabus of lecture and one semester of laboratory. The document is not a text manuscript, but an all-inclusive listing of a general biology syllabus broken down by subject.
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GUZMÁN, COLÍN RICARDO ALEJANDRO. "MANUAL DE PROCEDIMIENTOS PARA EL MANEJO DEL RATÓN EN UN BIOTERIO DE DOBLE PROPOSITO EN EL LABORATORIO ESTATAL DE SALUD PÚBLICA DEL INSTITUTO DE SALUD DEL ESTADO DE MÉXICO." Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2017. http://hdl.handle.net/20.500.11799/67799.
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La Organización Mundial de la Salud (OMS) estimó que durante el 2015, en el mundo se registraron 55 mil muertes de seres humanos que fueron asociadas a infección del virus de la rabia, la mayoría de estos casos se presentaron en Asia y África, entre el 30-50% de los casos fueron menores de edad (OMS, 2015). La rabia es una enfermedad contagiosa aguda y mortal, producida por un Rabdovirus que pertenece a la familia Rhabdoviridae del género Lyssavirus (Baer, 2000; CICUAL- UNAM, 2014). La transmisión del virus, se da de forma directa a través de mordedura de animales infectados a especies mamíferas (NOM-011-SSA2 2011; CONAVE, 2012).
A nivel nacional, el Centro Nacional de Programas Preventivos y Control de Enfermedades (CENAPRECE) estimó que anualmente, 90 mil personas son agredidas por alguna especie animal, entre las que destacan el perro y gato (SENASICA, 2015). A nivel nacional, se reportaron 25 casos positivos de rabia durante el 2015, mientras que, en el Estado de México, el Laboratorio Estatal de Salud Pública del Instituto de Salud del Estado de México (LESP-ISEM) reportó casos positivos en especies pecuarias durante los últimos años. El LESP-ISEM se ubica en Toluca, Estado de México, pertenece a la Red Nacional de Laboratorios de Diagnóstico de la Secretaría de Salud. Ahí se realiza el diagnóstico del virus de la rabia en muestras sospechosas (animales de monitoreo, animales agresores, animales sintomáticos y casos humanos sospechosos) que cumplen con los criterios establecidos en los Lineamientos para la Vigilancia Epidemiológica de Rabia por Laboratorio. En el Instituto de Diagnóstico y Referencia Epidemiológicos. Durante 2015 se procesaron 7880 muestras de animales provenientes de todo el Estado de México.
Este manual deberá suministrar los procedimientos adecuados para el manejo de los ratones BALB/c, así como recomendaciones generales para un funcionamiento adecuado de las instalaciones y deberá registrarse en los formatos que generaran una bitácora la cual se deberá conservar año con año, teniendo una vigencia de 5 años.
Los formatos presentados en este manual de procedimientos han sido probados y aceptados por los directivos de las instalaciones del LESP, los cuales garantizan el bienestar animal y un apropiado uso de las instalaciones, así como buenas prácticas de laboratorio y almacenamiento y eliminación de desechos biológico infecciosos; esto apegado a las NOM-062-ZOO-1999 y NOM-087-ECOL-SSA1-2002.
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Yang, Jing. "Determination of peramivir and its toxicokinetics in beagle dogs." Thesis, University of Macau, 2011. http://umaclib3.umac.mo/record=b2524966.
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Berkholz, Petra [Verfasser]. "Laboratory Investigation of Manual Dishwashing Habits and its Resource Consumptions: A Study of Consumer Panels in Seven Global Regions / Petra Berkholz." Aachen : Shaker, 2016. http://d-nb.info/1094396583/34.
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Hrubá, Lucie. "Vypracování příručky jakosti pro hydrochemické laboratoře." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2009. http://www.nusl.cz/ntk/nusl-216550.
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The thesis is oriented on working-out of the quality manual for hydrochemical laboratory conformable with standards ISO 9000 and 16000. The quality manual describes principles and working processes for utilisation in standard audited and accredited hydrochemical laboratory. It is focused on management system of quality created in laboratory in conformity with standard ČSN EN ISO 9001. It presents basic information about politics and goals of laboratory´s quality. In the practical part of the thesis, there are reviews of various Standards operation procedure, which are components of the Quality Manual.
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Andersson, Vidar. "Evaluation of CellaVision DM1200 Vet and its ability to differentiate feline leukocytes compared to manual differential count and Advia 2120." Thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-295630.
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Leukocyte differential count in peripheral blood smear has, ever since the method was developed more than 100 years ago, been one of the most frequently used diagnostics tool in the routine hematology laboratory. The manual differential count of leukocytes using a microscope is still the standard method in most small and medium sized laboratories. Even though the method does not require any expensive instruments it comes at a high cost due to it being labor intensive and time consuming. In recent years the rapid technical advancements has led to the development of automatic or semi-automatic methods in which the leukocytes are differentiated. In this study a method comparison was made between manual leukocyte differential counts, CellaVision DM1200 Vet and Advia 2120 when analyzing 106 fresh, feline blood samples. The general agreement between results was good, especially for the most common leukocytes, such as neutrophils and lymphocytes. Results for eosinophils and monocytes had moderate agreement. The confidence intervals were generally wider when CellaVision DM1200 Vet was compared with Advia 2120, than when CellaVision DM1200 Vet was compared to the manual differential count. Despite the fact that Advia 2120 and CellaVision DM1200 Vet are both faster and often show comparable results to the manual differential count, the light microscopy will remain the gold standard for difficult samples, where there is suspicion of inflammation (band neutrophils), intracellular microorganisms, reactive lymphocytes or if the sample contains a high degree of smudge cells or artifacts.
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Johnson, Sarah R. "Facilitating Conceptual Learning in Quantitative Chemistry." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etd/2617.
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Traditional chemistry laboratory courses have a manual consisting of “step-by-step” experiments; instructions are given to complete experiments, requiring minimal information/concepts processing to be successful. This experience leaves students unprepared for the real-world, where critical thinking skills are needed to conduct research. This study focused on building analytical techniques, conceptual knowledge, and critical thinking skills used to solve research problems. A new quantitative chemistry laboratory manual was developed to transition students from traditional to inquiry-based experiments, requiring analytical method development. Data showed students having less difficulty using the new manual (0.8281 average difficulty) on method development exam questions and experiments, compared to the traditional manual (0.600 average difficulty). T-test showed significant difference between item difficulty, p = 0.029. Using null hypotheses, the new laboratory manual led to an increase in students’ conceptual knowledge and research skills. They were able to use their knowledge and skills to successfully solve real-world related problems.
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Chroustovská, Kateřina. "Příprava diagnostické laboratoře pro akreditaci." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2021. http://www.nusl.cz/ntk/nusl-442428.
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This diploma thesis deals with the topic of accreditation of a diagnostic laboratory. It analyses theoretical knowledge in the field of accreditation, accreditation agency and its history. It contains a list and sample of documents required for accreditation and a description of the process. Part of the work is also a description of the requirements arising from the standard ČSN EN ISO / IEC 17025. The work briefly introduces the company whose laboratory is to be accredited. The following are the technologies the company uses and wants to accredit. The main part of this diploma thesis is the Quality manual, which was created with all needed attachments. This Quality manual is the most significant document, which is necessary for the process of accreditation.
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Nader, Athir. "Engineering Characteristics of Sensitive Marine Clays - Examples of Clays in Eastern Canada." Thèse, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/30670.
Full textAbstract:
Sensitive marine clay in Ottawa is a challenging soil for geotechnical engineers. This type of clay behaves differently than other soils in Canada or other parts of the world. They also have different engineering characteristic values in comparison to other clays. Cone penetration testing in sensitive marine clays is also different from that carried out in other soils. The misestimation of engineering characteristics from cone penetration testing can result. Temperature effects have been suspected as the reason for negative readings and erroneous estimations of engineering characteristics from cone penetration testing. Furthermore, the applicability of correlations between cone penetration test (CPT) results and engineering characteristics is ambiguous. Moreover, it is important that geotechnical engineers who need to work with these clays have background information on their engineering characteristics.
This thesis provides comprehensive information on the engineering characteristics and behaviour of sensitive marine clays in Ottawa. This information will give key information to geotechnical engineers who are working with these clays on their behaviour. For the purpose of this research, fifteen sites in the Ottawa area are taken into consideration. These sites included alternative technical data from cone and standard penetration tests, undisturbed samples, field vanes, and shear wave velocity measurements. Laboratory testing carried out for these sites has resulted in acquiring engineering parameters of the marine clay, such as preconsolidation pressure, overconsolidation ratio, compression and recompression indexes, secondary compression index, coefficient of consolidation, hydraulic conductivity, clay fraction, porewater chemistry, specific gravity, plasticity, moisture content, unit weight, void ratio, and porosity. This thesis also discusses other characteristics of sensitive marine clays in Ottawa, such as their activity, sensitivity, structure, interface shear behaviour, and origin and sedimentation.
Furthermore, for the purpose of increasing local experience with the use of cone and ball penetrometers in sensitive marine clays in Ottawa, three types of penetrometer tips are used in the Canadian Geotechnical Research Site No. 1 located in south-west Ottawa: 36 mm cone tip, and 40 mm and 113 mm ball tips. The differences in their response in sensitive marine clays will be discussed. The temperature effects on the penetrometer equipment are also studied. The differences in the effect of temperature on these tips are discussed. Correlations between the penetrometer results and engineering characteristics of Ottawa's clays are verified.
The applicability of correlations between the testing results and engineering characteristics of sensitive marine clays in Ottawa is also presented in this thesis. Two correlations from the Canadian Foundation Engineering Manual are examined. One of these correlations is between the N60 values from standard penetration testing and undrained shear strength. The other correlation is between the shear wave velocity measurement and site class. Temperature corrections are suggested and discussed for penetrometer equipment according to laboratory calibrations. The significance of the effects due to radical temperature changes in Canada and Ottawa is discussed.
Some of the main findings from this research are as follows.
• The Canadian Foundation Engineering Manual presents a correlation between standard penetration tests (SPTs) and the undrained shear strength of soils. This relationship may not be applicable to sensitive marine clays in Ottawa.
• Another correlation between the site class, shear wave velocity, and undrained shear strength is presented by this same manual which may not be applicable to sensitive marine clays in Ottawa.
• The rotation rate for field vane testing as recommended by ASTM D2573 is slow for sensitive marine clays in Ottawa.
• Correction factors applied to undrained shear strength from laboratory vane tests may not result in comparable values with the undrained shear strength obtained by using field vane tests.
• Loading schemes in consolidation or oedometer testing may affect the quality of the targeted results.
• Temperature corrections should be applied to penetrometer recordings to compensate for the drift in the results of these recordings due to temperature changes.
• The secondary compression index to compression index ratio presented in the literature may not be the value obtained from this research.
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Pinheiro, Maria do Carmo Gomes. "EquivalÃncia farmacÃutica: proposta de manual para a implantaÃÃo e a padronizaÃÃo de centros em conformidade com as normas tÃcnicas e a legislaÃÃo sanitÃria vigentes." Universidade Federal do CearÃ, 2004. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=346.
Full textAbstract:
CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel SuperiorCom a implantaÃÃo da polÃtica de incentivo ao medicamento genÃrico, no Brasil, em 1999, os estudos de equivalÃncia farmacÃutica tornaram-se elementos estratÃgicos para a sua implementaÃÃo e seu Ãxito. Para a realizaÃÃo desses estudos, foi criada uma rede de laboratÃrios, habilitados e supervisionados pela AgÃncia Nacional de VigilÃncia SanitÃria, sob a denominaÃÃo de centros de equivalÃncia farmacÃutica (EQFAR), que passaram a integrar a Rede Brasileira de LaboratÃrios AnalÃticos em SaÃde (Reblas). Os critÃrios para a habilitaÃÃo e operaÃÃo dos centros, bem como para a realizaÃÃo, de maneira padronizada, dos estudos de equivalÃncia farmacÃutica, foram definidos por meio de um conjunto de regulamentos (leis, resoluÃÃes e normas tÃcnicas) cuja abrangÃncia, variedade e extensÃo nem sempre facilitam seu conhecimento, compreensÃo e aplicaÃÃo correta, tanto por parte dos interessados na implantaÃÃo desses centros como dos agentes de vigilÃncia sanitÃria no seu trabalho de avaliaÃÃo, habilitaÃÃo e fiscalizaÃÃo dos Centos e de coordenaÃÃo da rede. Este material consolida o conteÃdo dos regulamentos em vigor, sistematizando-os segundo os seguintes capÃtulos: documentaÃÃo de referÃncia, pessoal, biosseguranÃa e organizaÃÃo laboratorial, instalaÃÃes e acomodaÃÃes ambientais, sistema da qualidade, equipamentos, materiais de laboratÃrio e os principais ensaios que compÃem os estudos de equivalÃncia farmacÃutica e elaboraÃÃo do certificado analÃtico. Objetiva facilitar, por meio de sua manualizaÃÃo, o acesso dos interessados na implantaÃÃo e operaÃÃo de centros de equivalÃncia farmacÃutica e dos agentes de vigilÃncia sanitÃria à informaÃÃo sistematizada e consolidada sobre a matÃria
In 1999, the policy of generic medicaments was implemented in Brazil, and the availability of pharmaceutical equivalence essays became strategic for its success. A group of laboratories was identified, evaluated and qualified, as a network, by the National Sanitary Surveillance Agency (Anvisa) to perform such studies. These laboratories were named âcenters for pharmaceutical equivalenceâ (EQFAR), and were integrated to The Brazilian Network of Analytical Laboratories on Health (REBLAS). The criteria for qualification and operation of the centers, as well as to perform standardized pharmaceutical equivalence essays, were established by a set of regulations (laws, resolutions and technical rules). The extent, diversity and complexity of these regulations do not always facilitate its knowledge, comprehensive and correct application for people interested in implementation of those rules on the centers as well as the National Sanitary Surveillance Agency tasks of evaluation, qualification and audition. This material consolidate the content of the regulation in force, systematizing them according the following chapters: referential documentation, human resources, biosafety and laboratorial organization, facilities and installations, quality assurance, equipment, materials, and the principals essays that compose the studies of pharmaceutical equivalence and the preparation of their analytical certification. It aims to be a practical instruction â like a manual â that allows the rapid access to the weighty information and to facilitate the work of people interested in implement a center of pharmaceutical equivalence and for those from the Sanitary Surveillance Agencies
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Bassey-Duke, Elizabeth Misan. "An ergonomics intervention study into the physiological, perceptual and productivity effects of three citrus harvesting bag designs in the Eastern Cape of South Africa : a combined laboratory and field approach." Thesis, Rhodes University, 2015. http://hdl.handle.net/10962/d1018908.
Full textAbstract:
Background: Agriculture plays a vital role in the economy of any industrially developing country, including South Africa. In the Eastern Cape of South Africa citrus farming is a significant contributor to the local economy (Johnson et al., 2005). The harvesting phase of citrus farming is performed manually and exposes workers to physical risks, which can lead to the development of musculoskeletal disorders. In particular, the standard harvesting bag comprises of a single shoulder strap and promotes asymmetrical load carriage which results in shoulder and lower back pain complaints. The current study compared the physiological (EMG), perceptual (RPE), usability (PUEU) and productivity effects of two new harvesting bag designs (a hip belt and a backpack bag design) to the standard harvesting bag design. This was performed in a laboratory as well as a field setting. Methods (Laboratory phase): 36 participants (12 males and 24 females) were assigned to one worker group. The “tall ladder worker” group was comprised of only males and the “step ladder worker” and “ground worker” group of females. Each participant was required to simulate a citrus harvesting task while utilizing each of the bag designs on different days. On each day/test session, participants performed three harvesting cycles. Muscle activity was measured throughout the entire testing session and RPE were recorded at the end of each cycle. Results (Laboratory phase): The EMG and RPE results indicate that the backpack design was the most ideal design to reduce asymmetry, while the standard harvesting bag design was the worst. Although not significant, there was greater muscle asymmetry (p=0.109) and a significantly higher perceived exertion when using the standard bag (p=0.0004), in comparison to using the backpack. Methods (Field phase): 17 Xhosa-speaking citrus harvesters (6 females and 11 males) participated in this study. Each harvester worked with one of the three bag designs on a different day. Productivity of each worker was assessed every hour by recording the number of bags filled with fruit and at the end of the shift. A Perceived Usefulness & Ease of Use questionnaire was presented to each participant to obtain feedback on worker acceptance to the new bag designs. Results (Field phase): A general trend in support of the hip belt bag design over the other two bag designs were found, even within the different worker demographic groups (age, sex and worker experience). The workers perceived less exertion (7.98 ± 1.86) and were more productive (9.90 ± 2.11 bags/hour) when using the hip belt design; they also found this bag the most useful (1.02 ± 0.09) and easy to use (1.07 ± 0.25). In contrast, the backpack bag design had significantly poorer responses when compared to the other two bag designs and this was evident in all the dependent variables assessed (RPE, productivity and PUEU). Conclusion: The results from the laboratory phase supported the expectation that the backpack bag design reduces asymmetry and hence, is more suitable than the standard harvesting bag. However, results from the field show that the hip belt bag design was the most preferred and the backpack was the least preferred. Bao & Shahnavaz (1989) highlight the need for ergonomics researcher to convey laboratory findings into the field context. However, as shown by the current study, there are numerous challenges associated with field work, making it difficult for laboratory findings to be successfully conveyed to the field. Limitations and Recommendations: For the laboratory phase of the project, no biomechanical and cardiovascular responses were assessed. However, for a holistic approach, these variables should be considered in future studies. Due to high variability from one harvesting cycle to another, more than three harvesting cycles should also be performed to accurately replicate the harvesting process as done in the field over extended durations of time. For the field phase, data should be collected from more than one citrus farm and thus a larger sample size could be obtained. This would improve the validity of the study. In addition to this, data should be collected for a full working day, especially if environmental conditions are not a hindrance, as well as for a whole season, since workloads vary, depending on the time of the harvesting season.Name on Graduation Programme: Bassey-Duke, Elizabeth Missan