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Dissertations / Theses on the topic 'MAP-Kinase'

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Published: 4 June 2021

Last updated: 5 October 2024

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1

Wan, Omar Wan Bayani. "Studies into interactions between MAP kinase and MAP kinase kinase proteins of Arabidopsis." Thesis, Heriot-Watt University, 2011. http://hdl.handle.net/10399/2490.

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The Arabidopsis thaliana genome contains genes encoding 10 MAP kinase kinase (MKK) and 20 Map kinase (MAPK) proteins, however the exact relationship between upstream MKK activators and downstream MAPK protein partners has not fully elucidated. In this study, the yeast two -hybrid system was used to identify protein-protein interactions between all Arabidopsis MAPKs and MKKs. In the yeast two- hybrid assay, the result from the qualitative β-galactosidase filter assay showed that 6 MAPK proteins interacted with 6 MKK proteins. Quantitative β-galactosidase liquid assay was used to confirm the int

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2

Kidger, Andrew M. "The regulation of oncogenic MAP kinase signalling by dual-specificity MAP kinase phosphatases." Thesis, University of Dundee, 2016. https://discovery.dundee.ac.uk/en/studentTheses/4a53a409-1276-4fa5-9a40-8b79b0a0af1c.

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Oncogenic activation of the Ras-ERK pathway is frequently observed in human cancers. Dual-specificity MAP kinase phosphatases (DUSPs or MKPs) are important negative regulators of this pathway and could therefore play an important role in modulating the oncogenic potential of signalling. DUSP5 and DUSP6/MKP-3 are ERK-specific MKPs, which are classical negative feedback regulators of pathway activity, but are differentially localised, with DUSP5 found in the nucleus and DUSP6/MKP-3 in the cytoplasm. However, to date their potential roles in modulating the oncogenic potential of the Ras-ERK pathw

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3

Sengar, Ameet Singh. "Mkh1, a novel MAP kinase kinase kinase in Schizosaccharomyces pombe." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq20852.pdf.

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4

Holland, Pamela M. "Identification, interactions, and specificity of a novel MAP kinase kinase, MKK7 /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/9262.

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5

Fox, Gavin Connor. "Structural studies on MAP kinase phosphatases and the receptor tyrosine kinase TrkA." Thesis, Birkbeck (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268768.

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6

Holzberg, David Alexander. "Untersuchungen zur spezifischen Funktion von JNK-Signalwegen mit Hilfe von zellpermeablen Peptiden und tandem affinity purification." [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972264175.

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7

Dangers, Marc. "Charakterisierung von assoziierten Proteinen der Protein-Kinase Raf-1." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=972557725.

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8

Kim, Jin Ah. "Le rôle du MAPK (Mitogen-Activated Protein Kinase) et CDKs dans la phase G2/M." Université Joseph Fourier (Grenoble), 2008. http://www.theses.fr/2008GRE10172.

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Les points de contrôle du cycle cellulaire assurent la stabilité du génome en retardant la progression du cycle en réponse à des stress ou des dommages causés sur l'ADN. Le point de contrôle de la phase G2 régule l'entrée des cellules en mitose, tandis que le point de contrôle de la formation des fuseaux mitotiques prévient l'entrée en anaphase, jusqu'à ce que les chromosomes soient correctement alignés. Au cours de ma thèse, je me suis intéressée à l'étude des Rôle de MAPKs (Mitogen-Activated Protein Kinases) et de la protéine P21 qui est un inhibiteur de cdk (cyclin dependent kinase), dans l

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9

Teoh, Peik Lin. "Mechanisms of MAP kinase signaling to transcriptional regulators." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/mechanisms-of-map-kinase-signaling-to-transcriptional-regulators(390ffd58-c599-4186-b9df-497850de0794).html.

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The MAPK pathway is important in various biological functions. It is also important in regulating processes associated with gene transcription via different mechanisms such as by phosphorylation of transcription factors, coactivators/corepressors and histone modifier complexes. H3K4 methylation is highly associated with active transcription. Deposition of this mark is catalysed by SET-domain methyltransferases which consists of a WAR complex (WDR5, ASH2L and RBBP5), a catalytic SET-domain protein and other subunits. However, potential links between ERK MAPK signaling and H3K4 methylation in ge

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10

KRADY, MARIE-MARTHE. "Regulation de la map kinase dans le noyau." Université Louis Pasteur (Strasbourg) (1971-2008), 1999. http://www.theses.fr/1999STR13148.

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Les erk/map kinases sont des serine/threonine kinases qui sont activees apres la phosphorylation de residus threonine et tyrosine. Elles sont egalement regulees par les tyrosine phosphatases ou par les phosphatases a double specificite. L'inhibition des tyrosine phosphatases par le pervanadate dans les fibroblastes c3h 10t1/2 au repos (g0/g1), induit une activation prolongee de la map kinase, sa translocation dans le noyau et la proliferation des cellules. L'activation de la map kinase et la proliferation cellulaire stimulees par le serum ou le tpa sont inhibees par le pd 98059, un inhibiteur

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11

Chen, Mingzi. "Mos regulation in activating the MAP kinase pathway /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/9195.

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12

Gopalbhai, Kailesh. "Régulation négative des MAP kinase kinases par phosphorylation /." [Montréal] : Université de Montréal, 2003. http://wwwlib.umi.com/cr/umontreal/fullcit?pNQ92759.

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Thèse (Ph.D.) -- Université de Montréal, 2004.<br>"Thèse présentée à la Faculté des études supérieures en vue de l'obtention du grade de Philosophiae Doctor en Pharmacologie" Version électronique également disponible sur Internet.

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13

Naik, Vikram Verfasser], and Regine [Akademischer Betreuer] [Kahmann. "The Ustilago maydis MAP kinase signaling pathway: Identification of MAP kinase targets by phospho-peptide enrichment / Vikram Naik. Betreuer: Regine Kahmann." Marburg : Philipps-Universität Marburg, 2015. http://d-nb.info/1077866879/34.

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14

Scimeca, Jean-Claude. "La map-kinase erk1 : mecanisme d'activation et association avec une rsk (ribosomal s6 kinase)." Nice, 1992. http://www.theses.fr/1992NICE4597.

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Nous nous sommes interesses a la recherche et a la caracterisation de serine/threonine kinase(s), regulee(s) par les recepteurs tyrosine kinases et phosphorylee(s) sur tyrosine. L'utilisation de fibroblastes de souris exprimant le recepteur humain de l'insuline, incubes en presence d'insuline ou d'orthovanadate de sodium, nous a permis d'observer au moins trois activites serine kinases de 30 kd environ (determine par filtration sur gel), phosphorylees sur tyrosine et tres probablement regulees par cette phosphorylation. Nous avons ensuite etudie le mode d'activation d'erk1, une map-kinase de 4

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15

King, Victoria Ann. "Studies on the Cell Integrity MAP kinase of yeast." Thesis, University of Sheffield, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485115.

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The yeast cell integrity MAP kinase SIt2p binds the Hsp90 molecular chaperone (Millson el aI., 2005), making it an ideal model client protein of Hsp?O in the easily manipulatable yeast Saccharomyces cerevisiae. This study was aimed at investigating several aspects of the control ofSlt2p. A two-stage purification method, using IMAC and TAP, was employed to isolate the Hsp90:S1t2p complex to gain insight into the Hsp90 facilitated activation of SIt2p (MiIlson el al., 2005). This met limiting success, isolating only Hsp82, and potentially Hsc82, in the final purification stages. TAP alone using S

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16

Plamondon, Philippe. "La MAP kinase p38γ influence la structure des cardiomyocytes". Mémoire, Université de Sherbrooke, 2014. http://savoirs.usherbrooke.ca/handle/11143/5307.

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Le cœur est un organe central au fonctionnement du système cardiovasculaire. Il est physiologiquement compartimenté et est constitué de cellules spécialisées qui régulent les impulsions électriques ainsi que la contraction du myocarde. Le cœur adapte le flux sanguin en fonction des besoins du corps. En condition pathologique, le cœur recourt toutefois à des mécanismes compensatoires. Au niveau physiologique, la compensation s’observe par l’hypertrophie des cardiomyocytes qui, bien que bénéfique à court terme, exacerbe à long terme la fonction cardiaque. L’activation des « mitogen activated pro

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17

Larman, Mark Graham. "Calcium and MAP kinase regulation during the cell cycle." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340683.

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18

Moody, Steven James. "MAP kinase activity in the wound response of tomato." Thesis, University of York, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325646.

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19

Sundaresan, Pavithra. "Platelet collagen receptors and regulation of p38 MAP kinase." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619577.

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20

Cayla, Mathieu. "Caractérisation fonctionnelle de la MAP kinase MPK10 de Leishmania." Paris 7, 2014. http://www.theses.fr/2014PA077252.

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Les protozoaires pathogènes du genre Leishmania ont développé des mécanismes uniques de signalisation leur permettant de détecter des changements dans leur environnement. Ces changements vont permettre leur différenciation, étape essentielle pour assurer leur survie et leur croissance dans la cellule de l'hôte mammifère. Peu de choses sont connues sur les mécanismes mis en jeu lors de la différenciation, mis à part le rôle essentiel joué par les MAP kinases (MAPKs) et la phosphorylation des protéines. Mes travaux de thèse ont permis i) de mettre en évidence les mécanismes de régulation de MPK1

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21

CHEDOTAL, MARIE-HELENE. "Map kinase et maturation meiotique de l'ovocyte de souris." Paris 6, 1995. http://www.theses.fr/1995PA066051.

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Les map (mitogen activated protein) kinases, ou erk (extracellular regulated kinases), sont impliquees dans de nombreux processus tels que la proliferation cellulaire, la differenciation cellulaire, et notamment lors de la meiose chez le xenope et la palourde. De nombreuses etudes, portant sur des systemes tres eloignes (levure, mammifere) ont montre l'importance des map kinases dans la transduction de signaux extracellulaires. Au cours de ma these je me suis interessee au role de ces proteines lors de la maturation meiotique et de la fecondation de l'ovocyte de souris. J'ai caracterise les ma

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22

Berriri, Souha. "Identification of constitutively active forms of Arabidopsis MAP Kinases : brings more evidence on MPK4 function in plant immunity." Thesis, Evry-Val d'Essonne, 2012. http://www.theses.fr/2011EVRY0024.

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La phosphorylation/déphosphorylation des protéines est un mécanisme de signalisation intracellulaire commun. Parmi les kinases végétales, les Mitogen-Activated Protein Kinases (MAPKs) sont impliquées dans de nombreux processus biologiques importants, comme la réponse aux stress biotiques et abiotiques, le développement et la dynamique du cytosquelette. Chez Arabidopsis thaliana et ce malgré de nombreux efforts, les fonctions des kinases impliquées dans les cascades MAPK restent peu inconnues. L'activation des kinases en utilisant des mutations mimant la phosphorylation des sites normalement ph

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23

Morel, Caroline Isabelle. "Interactions croisées entre inhibiteurs de MAP Kinases et analogues de la cholécystokinine sur leur cible respective : le récepteur de type 1 et P38 MAP Kinase : étude pharmacologique et moléculaire." Montpellier 1, 2004. http://www.theses.fr/2004MON13519.

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La cholécystokinine est une hormone peptidique majeure du tractus gastro-intestinal et du système nerveux central. Elle est impliquée dans de nombreuses fonctions biologiques au travers de sa liaison sur le récepteur CCKl, parmi lesquelles la sécrétion d'enzymes digestives et la régulation de la satiété. Elle est également responsable de l'activation des différentes voies de transduction du signal telle que la voie p38 MAP kinase, au niveau des acini pancréatiques de rat. P38 MAP kinase est une enzyme clé des réponses inflammatoires et de nombreux composés ont été développés pour inhiber son a

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24

Mazharian, Alexandra. "Rôle complémentaire des MAP Kinases ERK2, p38 et JNK1 dans l'activation plaquettaire." Paris 7, 2007. http://www.theses.fr/2007PA077217.

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Les MAP Kinases (MAPK) sont des sérine/thréonine kinases regroupées en trois familles: les «Extracellular signal-RegidatedKinases» (ERKs), les p38MAPKs et les «c-jun N-terminal Kinases» (JNKs). L'étude des MAPK dans les plaquettes présente un double intérêt. Elle permet d'identifier de nouvelles cibles et de nouveaux rôles notamment dans l'hémostase et la thrombose. Dans la première étude, nous montrons un rôle complémentaire d'ERK2 et p38 dans l'adhérence des plaquettes sur une matrice de collagène, En effet, ERK2 dépend des taux de cisaillement et de l'interaction vWF/GPIb. En revanche p38,

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25

Chetoui, Nizar. "Caractérisation du rôle de la protéine kinase MEK1 dans les voies de transduction des MAP kinases." Thesis, Université Laval, 2005. http://www.theses.ulaval.ca/2005/22589/22589.pdf.

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Le développement tumoral nécessite une dérégulation des contrôles normaux de la prolifération et de la différenciation cellulaires. Il est bien connu que la voie de signalisation ERK/MAP kinase est impliquée dans ces processus de régulation cellulaire. De plus, un rôle essentiel dans la transformation cellulaire est attribué à MEK1 qui est un élément central de cette voie. Une meilleure compréhension de l’implication de MEK1 dans les voies de transduction devrait donc nous permettre de mieux comprendre le developpement cellulaire et la transformation morphologique. Mes travaux de recherche ten

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26

Todorovic, Zana. "Regulation of the MAP kinase pathway in Y1 adrenal cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ45474.pdf.

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27

Le, Thuyanh. "Regulation of the MAP kinase pathway in Y1 adrenal cells." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0001/MQ46143.pdf.

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28

Danboise, Brook Alicia. "Role of MAP Kinase in Fusarium Association With Contact Lenses." Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/biology_diss/45.

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Fusarium solani is a soil-borne pathogen devastating agricultural crops throughout the world. While most pathogens are host specific, the fusaria are able to infect both plants and animals. In 2004, an outbreak of Fusarium occurred in association with contact lens wear. Several species of Fusarium were involved but F. solani and F. oxysporum were most prominent. In this work, we have identified a MAP kinase (MAPK), highly similar to fmk1 in F. oxysporum, belonging to the YERK1 subfamily of extracellular regulated kinases. Directed disruption of fmk1 in F. solani AFR4 (FSSC 1) affected several

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29

Huang, Hao 1967. "Transcript profiling of a MAP kinase pathway in C. albicans." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=98726.

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In C. albicans, a MAP kinase pathway has been implicated in aspects of controlling hyphal development. We have examined the transcription profile of cells deleted for the transcription factor Cph1 as well as Cst20, Hst7 and Cek1, three upstream kinases potentially involved in Cph1 regulation. Deletion of these four elements does not block filament induction by serum and does not dramatically affect the transcription profile of yeast-hyphal transition, but deletion of CPH1 delays filamentation. Over-expression of Cph1 by ADH1pt-CPH1 significantly enhances filamentation, suggesting that Cph1 is

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30

McNeill, Helen. "Angiotensin II and MAP kinase in the rat adrenal gland." Thesis, Queen Mary, University of London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268825.

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31

Huguet, Romain. "Comparative functional proteomics of MAP kinase signalling in Magnaporthe oryzae." Thesis, University of Exeter, 2010. http://hdl.handle.net/10036/118007.

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Rice blast disease is caused by the heterothallic ascomycete fungus Magnaporthe oryzae and is one of the most severe diseases of cultivated rice throughout the world. The PMK1 (Pathogenicity Mitogen-activated protein Kinase) gene in M. oryzae has been identified to play diverse roles during pathogenesis-related development. PMK1 regulates appressorium formation and infectious hyphal growth. PMK1 is functionally related to Saccharomyces cerevisiae FUS3 and KSS1 MAPK genes which regulate the transcription factor Ste12. The STE12 homologue in M. oryzae, MST12, has also been identified and is know

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32

March, Helen Nicola. "Regulation of AP-1 family proteins by MAP kinase pathways." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612889.

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33

Torrance, Emma. "MAP kinase phosphatase-2 in vascular smooth cell muscle function." Thesis, University of Strathclyde, 2013. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=23297.

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The progression of major cardiovascular disorders are a consequence of a pathophysiological modification within the blood vessel; a process often driven by vascular smooth muscle cell hyperproliferation. A major mechanism by which smooth muscle cell proliferation occurs involves ligand-induced activation of MAP kinase signalling (Schad et al., 2011). MAP kinases have been noteworthy but troublesome targets in cardiovascular therapeutics; thus exploration of targeting endogenous regulatory dual specificity proteins namely MAP kinase phosphatases has been advancing in recent years. Mitogen-activ

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34

Brixey, Rachel J. E. "Genetic analyses of MAP kinase signalling in mouse gonad development." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:54242de2-8e43-4cf2-ad12-d94a2c187c44.

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Sexual development begins with the process by which the bipotential gonads of the embryonic urogenital ridge develop into either testes or ovaries. In the mouse, sex determination occurs at around 11.5 dpc and depends on the presence or absence of the Y chromosome and the associated activity of the testis-determining gene, Sry, in supporting cell precursors. The mutually antagonistic male and female developmental pathways are regulated by many cellular and molecular processes, disruption of which can lead to disorders of sex development (DSDs). However, many of the molecular mechanisms regulat

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Beggs, James. "The MAP-kinase interacting kinases (Mnks) as targets in cancer." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/390651/.

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The Mnks appear to play an important role in tumour development, but are not essential for normal cell growth and development. This makes them attractive targets for designing anti-cancer treatments. The Mnks are directly downstream of the RAS-RAF-MEK-ERK pathway, a pathway that is frequently overactive in cancer cells. The Mnks bind to eIF4G, which is part of the translation initiation complex, and are the only kinases known to phosphorylate the 5’ mRNA cap-binding protein eIF4E. Despite numerous studies linking this phosphorylation event to cancer, its precise role in cancer remains unclear.

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Domeyer, David. "Docking-basiertes virtuelles Wirkstoff-Design von p38 MAP Kinase-Inhibitoren /." [S.l. : s.n.], 2005. http://www.gbv.de/dms/bs/toc/52427083X.pdf.

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37

Collins, Lila Rae. "MAP Kinase cascades in thrombin-stimulated mitogenesis and G₁₂signaling /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1997. http://wwwlib.umi.com/cr/ucsd/fullcit?p9805794.

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Chapman, Stephen Allen Asthagiri Anand R. Asthagiri Anand R. "Quantitative performance and tradeoffs in the MAP kinase signaling module /." Diss., Pasadena, Calif. : California Institute of Technology, 2009. http://resolver.caltech.edu/CaltechETD:etd-02202009-142419.

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Bruns, Svenja Anne [Verfasser]. "Autophagy regulation by the p38 MAP kinase / Svenja Anne Bruns." Magdeburg : Universitätsbibliothek, 2017. http://d-nb.info/1128726491/34.

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Jefferies, Matthew. "Evaluating synergy between deregulation of the Wnt, PI3-Kinase and MAP-Kinase pathways in prostate tumourigenesis." Thesis, Cardiff University, 2017. http://orca.cf.ac.uk/98127/.

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The Wnt, PI3-Kinase (PI3K) and MAP-Kinase (MAPK) cell signalling pathways play important roles in human prostate cancer (PCa). In this thesis, analysis of a human PCa tissue micro-array (TMA) constructed by the Welsh Cancer Bank demonstrated upregulation of markers associated with these pathways in PCa. There was also greater expression of these markers in high-risk tumours with some being predictive of biochemical recurrence following surgery. Furthermore, there is evidence to support cross talk between these pathways allowing clustering into low- and high-risk samples based on expression pro

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Ant, Cemile. "Rôle de la voie de signalisation MAP kinase Mps1 dans la pathogénie fongique et dans le contrôle de l'intégrité de la paroi." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00603704.

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L'intégrité de paroi cellulaire est cruciale pour la survie du champignon pendant son cycle de développement ou en réaction à des conditions de stress. Chez la levure, les voies de signalisation de MAP kinase, Slt2, et calcineurin, régulent la réparation de paroi cellulaire. MPS1, l'orthologue de SLT2, chez Magnaporthe grisea est essentiel pour la réparation de la paroi cellulaire et pour la pénétration de l'appressorium (Xu, et al., 1998). Chez la levure, Slt2 active les facteurs de transcription Rlm1, Swi4 et Swi6, alors que le calcineurin active Crz1. Par ailleurs, PaIdc1 a un rôle dans la

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42

Kinkel, Katrin. "Prediction of the binding mode of suberone-inhibitors in the p38 MAP kinase with molecular modeling studies." [S.l. : s.n.], 2008.

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43

Lehmann, Frank. "Struktur- bzw. Liganden-basierte Suche nach neuen p38 Mitogen-aktivierte Proteinkinase Pharmakophoren." [S.l. : s.n.], 2009.

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44

Duchene, Sophie. "Mécanismes de régulation de la synthèse proteique : voies de signalisation impliquées dans l'activation de la p70S6K chez le poulet." Tours, 2007. http://www.theses.fr/2007TOUR4036.

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La p70S6K, enzyme clé de la synthèse protéique, est classiquement activée en réponse à l’insuline par la voie PI3K. Dans le muscle du poulet, les effecteurs de cette voie PI3K : PKB, TOR, p70S6K, S6 et 4EBP1, sont phosphorylés, donc activés. Alors que le substrat du récepteur à l’insuline IRS1 est phosphorylé sur des sérines inhibitrices. L’étude de l’implication de la voie des ERK1/2 MAP kinases (caractérisation de ERK 2), révèle une forte participation de cette voie dans la stimulation de la p70S6K sur myoblastes, et une implication que partielle dans une lignée hépatocytaire LMH. Cette sign

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45

Garcia-Medina, Raquel. "Hypoxic signaling : the role of BNIP3 in proliferation and autophagy." Nice, 2008. http://www.theses.fr/2008NICE4044.

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As solid tumors grow the vascular network becomes insufficient for nutrient delivery and oxygen demand. The cells’ proximity to existing blood vessels leads to tumors characterized by areas of high oxygen tension interspersed with areas of relative hypoxia. Tumor cells respond by inducing and stabilizing the hypoxia-inducible factor 1 (HIF-1). HIF-1 regulates a complex gene expression network involved in the induction of angiogenesis, anaerobic metabolism, pHi regulation, migration and invasion, but also by decreasing tumor proliferation. The pathophysiological consequences and underlying mole

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46

Young, Stephen W. "The insulin receptor tyrosine kinase and the activation of the map kinase cascade : interactions with the protein kinase C and protein kinase A signalling pathways." Thesis, University of Bristol, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238958.

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47

Harding, Angus Silas. "A biochemical analysis of the MAP kinase pathway in mammalian cells /." A biochemical analysis of the MAP kinase pathway in mammalian cellsRead the abstract of the thesis, 2003. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17885.pdf.

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ICHIKAWA, KENJI, TAKANORI NAKAMURA, YUJI KUBOTA, and MUTSUHIRO TAKEKAWA. "REGULATION OF STRESS-ACTIVATED MAP KINASE PATHWAYS DURING CELL FATE DECISIONS." Nagoya University School of Medicine, 2011. http://hdl.handle.net/2237/14910.

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Ljungdahl, Sofia. "Role of MAP kinase pathways in maintenance of the transformed phenotype /." Stockholm, 1998. http://diss.kib.ki.se/1998/91-628-2829-0.

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Sloss, Callum. "Control of subcellular distribution of the MAP kinase phosphatase, MKP-2." Thesis, University of Strathclyde, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288715.

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