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1

Kim, Seung-Hyun, Michael Behnes, Michele Natale, et al. "Galectin-3 Reflects Mitral Annular Plane Systolic Excursion Being Assessed by Cardiovascular Magnetic Resonance Imaging." Disease Markers 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/7402784.

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Background. This study investigates whether serum levels of galectin-3 may reflect impaired mitral annular plane systolic excursion (MAPSE) in patients undergoing cardiac magnetic resonance imaging (cMRI).Methods. Patients undergoing cMRI during routine clinical care were included prospectively within an all-comers design. Blood samples for biomarker measurements were collected within 24 hours following cMRI. Statistical analyses were performed in all patients and in three subgroups according to MAPSE (MAPSE I: ≥11 mm, MAPSE II: ≥8 mm–<11 mm, and MAPSE III: <8 mm). Patients with right ve
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Nemes, Attila, Nóra Ambrus, and Csaba Lengyel. "Three-Dimensional Speckle-Tracking Echocardiography-Derived Left Ventricular Global Longitudinal Strain and Mitral Annular Plane Systolic Excursion Are Associated in Healthy Adults—Insights from the MAGYAR-Healthy Study." Biomedicines 13, no. 3 (2025): 625. https://doi.org/10.3390/biomedicines13030625.

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Introduction: Mitral annular plane systolic excursion (MAPSE) is a quantitative feature of left ventricular (LV) function that can be easily measured by M-mode echocardiography. The more recent LV strains represent LV contractility, and they can be determined for the three main directions in the radial (RS), longitudinal (LS), and circumferential (CS) directions. Three-dimensional (3D) speckle-tracking echocardiography (3DSTE) seems to be ideal for the simultaneous assessment of all LV strains from the same acquired 3D dataset. Their associations, however, have not been fully analyzed in clini
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Küçük, Uğur, Pınar Mutlu, Arzu Mirici, and Uğur Özpınar. "Mitral Annular Plane Systolic Excursion: An Early Marker of Subclinical Left Ventricular Function in COVID-19 Survivors." Iberoamerican Journal of Medicine 6, no. 2 (2024): 51–59. http://dx.doi.org/10.53986/ibjm.2024.0012.

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Introduction: The left ventricular (LV) function can be affected by COVID-19. Mitral annular plane systolic excursion (MAPSE) is a measurement that reflects the function of the LV. The association between MAPSE and LV function in COVID-19 survivors is not well understood, and this study aimed to explore that relationship. Material and methods: The retrospective cross-sectional study comprised 99 patients with a history of SARS-CoV-2 infection. These patients experienced symptoms lasting more than 2 months following the initial SARS-CoV-2 virus infection, including fatigue, shortness of breath,
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Nemes, Attila, Barbara Bordács, Nóra Ambrus, and Csaba Lengyel. "Longitudinal Systolic Excursion of the Mitral Annular Plane and Left Ventricular Rotational Mechanics Are Associated in Healthy Adults—Three-Dimensional Speckle-Tracking Echocardiography-Derived Insights from the MAGYAR-Healthy Study." Journal of Clinical Medicine 14, no. 9 (2025): 3201. https://doi.org/10.3390/jcm14093201.

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Introduction: The rotational mechanics of the left ventricle (LV) play a significant role in maintaining systemic circulation. In clinical practice, three-dimensional speckle-tracking echocardiography (3DSTE) is one of the first methods to be used that is suitable for routine, non-invasive investigations, even in healthy individuals, allowing the conduction of extensive but easily feasible tests. In routine clinical practice, mitral annular plane systolic excursion (MAPSE) is used as an easy-to-implement parameter to judge the systolic longitudinal function of the LV; its prognostic significan
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Rido, Muhammad, Khalid Saleh, A. Makbul Aman, Syakib Bakri, Haerani Rasyid, and Andi Alfian Zainuddin. "Correlation between mitral annular plane systolic excursion (MAPSE) at different degrees of ejection fraction in patients with diabetes mellitus." Romanian Medical Journal 71, no. 3 (2024): 248–52. http://dx.doi.org/10.37897/rmj.2024.3.15.

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Background and aim. Diabetic cardiomyopathy is characterized by myocardial structure and function abnormality in the absence of other cardiovascular risk factors. Early detection of cardiac dysfunction is crucial for timely intervention and improved patient outcomes. The purpose of this study is to determine how mitral annular plane systolic excursion (MAPSE) is a sensitive marker of early cardiac dysfunction in patients with diabetes mellitus by examining the relationship between MAPSE values and different levels of ejection fraction. Methods and material. An analytical cross-sectional study
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Aiwuyo, Henry Osarume, Osaretin John Osarenkhoe, Ejiroghene Martha Umuerri, et al. "Using Mitral Annular Plane Systolic Excursion (MAPSE) and Tissue Doppler Imaging Systolic Velocity (TDIS’) As Surrogates of Left Ventricular Systolic Function." International Journal of Health, Medicine and Nursing Practice 5, no. 2 (2023): 1–13. http://dx.doi.org/10.47941/ijhmnp.1252.

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Purpose: Echocardiography has become a useful method for assessing structural diseases of the heart. MAPSE and TDI S’ have also been shown to be reproducible assessments of longitudinal heart changes as LVEF is ineffective in cases of sub-optimal echocardiographic imagery caused by artefacts or air trapping.
 Methodology: One hundred patients referred for echocardiography at the cardiac laboratory of DELSUTH, Oghara, Nigeria was recruited for the study. All patients had trans-thoracic echocardiography done with M-Mode, 2D and Spectral Doppler and Tissue Doppler echocardiographic images ac
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Alatic, Jan, David Suran, Damijan Vokac, and Franjo Husam Naji. "Mitral Annular Plane Systolic Excursion (MAPSE) as a Predictor of Atrial Fibrillation Recurrence in Patients after Pulmonary Vein Isolation." Cardiology Research and Practice 2022 (September 27, 2022): 1–5. http://dx.doi.org/10.1155/2022/2746304.

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Introduction. Catheter ablation (CA) with pulmonary vein isolation (PVI) has become widely used in the past years for the treatment of atrial fibrillation (AF). Mitral annular plane systolic excursion (MAPSE) is the parameter that measures left ventricular longitudinal function, and it appears to be a good early marker of LV dysfunction. It is practically independent of poor image quality. The aim of our study was to analyse the role of echocardiographic variables, especially MAPSE in predicting the outcome of CA in patients with AF. Materials and Methods. We prospectively included 40 patients
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Cirin, Liviu, Simina Crișan, Constantin-Tudor Luca, et al. "Mitral Annular Plane Systolic Excursion (MAPSE): A Review of a Simple and Forgotten Parameter for Assessing Left Ventricle Function." Journal of Clinical Medicine 13, no. 17 (2024): 5265. http://dx.doi.org/10.3390/jcm13175265.

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Mitral annular plane systolic excursion (MAPSE) was a widely used and simple M-mode echocardiographic parameter for determining the left ventricle (LV) longitudinal systolic function. The purpose of this review is to analyze the use of MAPSE as a simple LV systolic function marker in different clinical scenarios, especially given the recent paradox of choices in ultrasound markers assessing cardiac performance. Recent data on the use of MAPSE in the assessment of LV function in different settings seem to be relatively scarce, given the wide variety of possible causes of cardiovascular patholog
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9

Qureshi, Azmat Ehsan, Najeeb Ullah, and Farid Ahmed Chaudhary. "MITRAL ANNULAR PLANE SYSTOLIC EXCURSION (MAPSE)." Professional Medical Journal 25, no. 11 (2018): 1622–26. http://dx.doi.org/10.29309/tpmj/18.4552.

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Background and Objectives: Assessment of left ventricle function is the singlemost common indication for transthoracic echocardiogram. Out of different indicators of LVfunction, ejection fraction is the most validated one. MAPSE has promised recently to be a reliableand easily obtainable indicator for LV function even in inexperienced hands but its value in caseof left ventricle hypertrophy (LVH) is questionable. Study Design: Cross-sectional comparativestudy. Setting: Rehmatul-lil-Alameen Institute of Cardiology, Lahore. Period: January 2015and March 2015. Methods: 100 consecutive patients pr
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10

Peixoto, Alberto Borges, Nathalie Jeanne Bravo-valenzuela, Wellington P. Martins, et al. "Reference ranges for the fetal mitral, tricuspid, and interventricular septum annular plane systolic excursions (mitral annular plane systolic excursion, tricuspid annular plane systolic excursion, and septum annular plane systolic excursion) between 20 and 36 + 6 weeks of gestation." Journal of Perinatal Medicine 48, no. 6 (2020): 601–8. http://dx.doi.org/10.1515/jpm-2020-0002.

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AbstractObjectivesThis study aimed to establish reference ranges for fetal mitral, tricuspid, and interventricular septum annular plane systolic excursions (MAPSE, TAPSE, and SAPSE) in normal pregnant women between 20 and 36 + 6 weeks of gestation.MethodsThis prospective and cross-sectional study included 360 low-risk singleton pregnancies between 20 and 36 + 6 weeks of gestation. MAPSE, TAPSE, and SAPSE were measured by M-mode in real time in an apical or basal four-chamber view through placing the cursor at the atrioventricular junction, marked by the valve rings at the tricuspid, mitral, an
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11

Paun, Nicolae, Ioan Tiberiu Nanea, Camelia Nicolae, et al. "The Significance of Ventricular Interdependence in Patients with Right Ventricular Hypertrophy and Normal Left Ventricular Function." Revista de Chimie 70, no. 10 (2019): 3689–93. http://dx.doi.org/10.37358/rc.19.10.7625.

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The aim of the study is to quantify ventricular interactions by comparing tissue and spectral systolic echocardiographic parameters to allow the early identification of ventricular dysfunction. Clinical, paraclinical, electrocardiographic and echocardiographic evaluations were performed. Right ventricular hypertrophy was diagnosed in the M mode subcostal echocardiographic section. RV hypertrophy was defined by a right ventricular free wall thickness of ] 5 mm in diastole. We assessed the following RV and LV tissue and spectral systolic indices: apical systolic excursion of the lateral mitral r
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12

Saputra, Bagus Made Indrata, Ida Bagus Rangga Wibhuti, Luh Oliva Saraswati Suastika, and Ni Made Ayu Wulan Sari. "The comparison of mitral annular plane systolic excursion (MAPSE) and mitral annular systolic velocity (Sm) in determining subclinical left ventricular systolic dysfunction in patients with type 2 diabetes mellitus." Indonesia Journal of Biomedical Science 16, no. 2 (2022): 70–77. http://dx.doi.org/10.15562/ijbs.v16i2.414.

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Background: Type 2 diabetes mellitus (T2DM) is an independent factor in increasing the risk of heart failure in the absence of coronary heart disease and hypertension. Global longitudinal strain (GLS) as the gold standard in determining subclinical left ventricular (LV) systolic dysfunction is not available on all echocardiographic tools and requires good-quality images. Mitral annular plane systolic excursion (MAPSE) and mitral annular peak systolic velocity (Sm) are simpler, faster, and widely available method that can determine left ventricular systolic dysfunction regardless of image quali
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13

Støylen, Asbjørn, Håvard Dalen, and Harald Edvard Molmen. "Left ventricular longitudinal shortening: relation to stroke volume and ejection fraction in ageing, blood pressure, body size and gender in the HUNT3 study." Open Heart 7, no. 2 (2020): e001243. http://dx.doi.org/10.1136/openhrt-2020-001243.

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BackgroundAims of this cross-sectional study were to assess: the relative contribution of left ventricular (LV) systolic long-axis shortening (mean mitral annular plane systolic excursion, MAPSE) to stroke volume (SV), the mechanisms for preserved ejection fraction (EF) despite reduced MAPSE, the age dependency of myocardial volume and myocardial systolic compression.MethodsLinear dimensions and longitudinal and cross-sectional M-modes were acquired in 1266 individuals without history of heart disease, diabetes or known hypertension from the third wave of the Nord-Trøndelag Health Study. Measu
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14

Muhrbeck, Josephine, Elif Gunyeli, Eva Andersson, Mahbubul Alam, Viveka Frykman, and Johanna Sjoblom. "Does stress echocardiography add incremental value to baseline ejection fraction for the early identification of candidates for implantable defibrillators?" Open Heart 6, no. 2 (2019): e001053. http://dx.doi.org/10.1136/openhrt-2019-001053.

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ObjectiveA reduction in left ventricular ejection fraction (EF) remains the strongest indicator of increased risk of sudden cardiac death after an acute myocardial infarction (AMI). Guidelines recommend that patients with an EF ≤35%, 6–12 weeks after AMI should be considered for implantable cardioverter defibrillator (ICD) therapy. Stress echocardiography is a safe method to detect viability in a stunned myocardium. The purpose of this study was to investigate if stress echocardiography early after AMI could identify ICD candidates before discharge.MethodsNinety-six patients with EF ≤40% early
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15

Rodríguez, M. "P06.09: Performance of TAPSE, MAPSE and TAPSE/MAPSE values in normal fetuses throughout gestation and in newborns by M-mode echocardiography." Ultrasound in Obstetrics & Gynecology 50 (September 2017): 172. http://dx.doi.org/10.1002/uog.18055.

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16

Syvolap, V. V., and V. A. Lysenko. "Is there the phenotype of chronic heart failure with “intermediate” left ventricular ejection fraction? Additional echocardiographic criteria for left ventricular systolic dysfunction in patients with chronic heart failure of ischemic origin with ejection fraction in the “gray area”." Zaporozhye Medical Journal 23, no. 3 (2021): 322–30. http://dx.doi.org/10.14739/2310-1210.2021.3.224710.

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Patients with chronic heart failure (CHF) with left ventricular ejection fraction (LV EF) in the range of 40–55 % form a separate group with “intermediate” or “moderately reduced” LV EF. Since there are a number of additional criteria in echocardiography other than EF for determining LV systolic function (TEI, MAPSE, systolic velocity of the fibrous ring of the mitral valve (S’), E/e’, dP/dt mitral regurgitation, etc.), their use may be helpful in the final identification of systolic dysfunction in CHF patients with LV EF within the “gray area”. The aim of the work – to find out the possibilit
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17

Ibrahimi, Pranvera. "Global dyssynchrony correlates with compromised left ventricular filling and stroke volume but not with ejection fraction or QRS duration in HFpEF." International Cardiovascular Forum Journal 1, no. 3 (2015): 147. http://dx.doi.org/10.17987/icfj.v1i3.40.

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Background and Aim: Mechanical global left ventricular (LV) dyssynchrony reflected as prolonged total isovolumic time<br />(t-IVT) has been introduced as a potential mechanism behind compromised stroke volume in heart failure (HF). It has also<br />been shown to be superior to other markers of dyssynchrony in predicting response to cardiac resynchronization therapy<br />(CRT), but its application in HF with preserved ejection fraction (HFpEF) remains unknown. The aim of this study was to<br />assess the role of t-IVT in explaining symptoms in HFpEF.<br />Methods:
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18

Karthik, N., G. Gnanavelu, N. Swaminathan, and S. Venkatesan. "Mitral annular plane excursion (MAPSE) correlation with ejection fraction in cardiovascular disease." Indian Heart Journal 69 (November 2017): S80. http://dx.doi.org/10.1016/j.ihj.2017.09.088.

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19

Agha, Hala M., Mahmoud A. Othman, Sonia El-Saiedi, et al. "Early onset left ventricular remodeling in juvenile systemic lupus erythematosus; Insight from 3-dimensional speckle tracking echocardiography." Lupus 30, no. 13 (2021): 2114–23. http://dx.doi.org/10.1177/09612033211051302.

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Background Early diagnosis and treatment of myocardial affection in patients with systemic lupus erythematosus (SLE) are crucial. Objectives To evaluate the ventricular systolic function in juvenile-onset systemic lupus erythematosus (j-SLE) patients by 3-D speckle tracking echocardiography (3D-STE) and to determine the predictors of left ventricular (LV) dysfunction if present. Methods Twenty-six SLE patients without heart failure and 21 healthy controls were studied by standard echocardiogram and 3D-STE. Conventional parameters included LV ejection fraction (EF), fractional shortening (FS),
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Bakalli, Aurora. "Relationship of Mitral Annular Plane Systolic Excursion (MAPSE) to Left Ventricular Thrombus Formation." Cardiology and Angiology: An International Journal 2, no. 4 (2014): 238–46. http://dx.doi.org/10.9734/ca/2014/10716.

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Borde, Deepak, S. Joshi, B. Asegaonkar, P. Apsingekar, S. More, and A. Deodhar. "MAPSE – a simple, reliable parameter of LV systolic function in patients undergoing OPCABG." Journal of Cardiothoracic and Vascular Anesthesia 32 (August 2018): S39—S40. http://dx.doi.org/10.1053/j.jvca.2018.08.088.

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Issa, Ziad, Nasser Moiduddin, Ziad Rafic Al Bulbul, and Giovanni Di Salvo. "27. New echocardiogram index alternatives to MAPSE and TAPSE z-scores in children." Journal of the Saudi Heart Association 27, no. 4 (2015): 310. http://dx.doi.org/10.1016/j.jsha.2015.05.208.

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Riesenkampff, Eugénie, Lena Mengelkamp, Matthias Mueller, et al. "Integrated analysis of atrioventricular interactions in tetralogy of Fallot." American Journal of Physiology-Heart and Circulatory Physiology 299, no. 2 (2010): H364—H371. http://dx.doi.org/10.1152/ajpheart.00264.2010.

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The atria play an important role in cardiac performance. We evaluated their function and the atrioventricular interaction in operated patients with tetralogy of Fallot (TOF). Twenty patients who had undergone surgical repair of TOF and seven controls were investigated. Patients had residual pulmonary but no major tricuspid valve insufficiency. Atrial and ventricular strain rates were obtained by echocardiographic speckle tracking. Cine MRI-derived volumetric analysis provided atrial and ventricular time volume and time volume change curves yielding emptying and filling parameters. In addition,
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Ravikanti, Karthik, Venu Yerramsetty, Ranjith Kumar, and Raymond Haward. "M-Mode in grade 3 dyspneic patients assessment." Halo 194 30, no. 1 (2024): 7–17. https://doi.org/10.5937/halo2401007r.

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Introduction/Objective Respiratory distress is a serious condition that can develop in the critically ill or those who have significant injuries. It is often fatal, and the risk of fatality increases with age and the severity of the illness. Therefore, an early diagnosis of the conditions that cause respiratory distress is an important factor. However, it is very challenging to make an accurate diagnosis in this domain. To clinically achieve higher accuracy during the diagnostic process, our study uses motion-mode (M-MODE) echo parameters. It aims to evaluate the accuracy of the M-MODE as a ra
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Puricelli, Filippo, Sabiha Gati, Winston Banya, et al. "Normal values of MAPSE and TAPSE in the paediatric population established by cardiovascular magnetic resonance." International Journal of Cardiovascular Imaging 38, no. 2 (2021): 407–9. http://dx.doi.org/10.1007/s10554-021-02415-9.

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Yan, Chengxi, Ying Chang, FangWu, et al. "Evaluation of the prognostic value of lateral MAPSE in patients with suspected coronary artery disease." IJC Heart & Vasculature 56 (February 2025): 101567. https://doi.org/10.1016/j.ijcha.2024.101567.

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Schick, Alexandra L., Josh C. Kaine, Nehal A. Al-Sadhan, et al. "Focused cardiac ultrasound with mitral annular plane systolic excursion (MAPSE) detection of left ventricular dysfunction." American Journal of Emergency Medicine 68 (June 2023): 52–58. http://dx.doi.org/10.1016/j.ajem.2023.03.018.

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Nair, Anupama, and Sitaraman Radhakrishnan. "Functional Assessment of Fetal Heart." Journal of The Indian Academy of Echocardiography & Cardiovascular Imaging 1, no. 2 (2017): 103–8. http://dx.doi.org/10.4103/jiae.jiae_55_17.

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Objective: To establish normative data for tissue Doppler indices and other parameters for ventricular function assessment in fetal imaging for the Indian population and to assess the variation of these parameters with gestational age. Materials and Methods: A prospective study involving 172 fetuses diagnosed as having normal cardiac structure and function. Mothers were advised for fetal echocardiography for several indications; however, mothers with diabetes (both gestational and pregestational), placental dysfunction, fetuses with intrauterine growth retardation, and multiple gestation were
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Pallavan N Swaminathan, Elayaraja. "Correlation of Mitral Annular Plane Systolic Excursion [Mapse] with Left Ventricular Ejection Fraction in Tertiary Care Centre." International Journal of Science and Research (IJSR) 12, no. 6 (2023): 201–4. http://dx.doi.org/10.21275/sr23530131323.

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Vasilcu, Teodor Flaviu, Andrei Drugescu, Mihai Roca, et al. "The Importance of Echocardiography Assessment in Coronary Patients Subject to Cardiovascular Recovery Programs." Internal Medicine 18, no. 5 (2021): 7–13. http://dx.doi.org/10.2478/inmed-2021-0178.

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Abstract Cardiovascular diseases cause approximately one-third of deaths worldwide and an increasing number of individuals with non-fatal ischemic heart disease live with chronic disabilities and impaired quality of life. Cardiac rehabilitation is designed to limit the physiological and psychological effects of cardiac illness, reduce the risk for sudden death or re-infarction, control cardiac symptoms and enhance the psychosocial and vocational status of selected patients. The study group included a group of 78 patients who had a coronary event no more than 3 months ago and who are included i
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Zhang, Hongmin, Hui Lian, Xiaoting Wang, Qing Zhang, and Dawei Liu. "Tricuspid annular plane systolic excursion/mitral annular plane systolic excursion ratio in critically ill patients: an index of right- and left-ventricular function mismatch and a risk factor for cardiogenic pulmonary edema." BMC Anesthesiology 23, no. 1 (2023). http://dx.doi.org/10.1186/s12871-023-02142-9.

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Abstract Background This study aimed to explore whether the tricuspid annular systolic excursion (TAPSE)/mitral annular systolic excursion (MAPSE) ratio was associated with the occurrence of cardiogenic pulmonary edema (CPE) in critically ill patients. Materials and methods This was a prospective observational study conducted in a tertiary hospital. Adult patients admitted to the intensive care unit who were on mechanical ventilation or in need of oxygen therapy were prospectively screened for enrolment. The diagnosis of CPE was determined based on lung ultrasound and echocardiography findings
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Berg, Erik Andreas Rye, Anders Austlid Taskén, Trym Nordal, et al. "Fully automatic estimation of global left ventricular systolic function using deep learning in transesophageal echocardiography." European Heart Journal - Imaging Methods and Practice, July 4, 2023. http://dx.doi.org/10.1093/ehjimp/qyad007.

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Abstract Aims To improve monitoring of cardiac function during major surgery and intensive care, we developed a method for fully automatic estimation of mitral annular plane systolic excursion (auto-MAPSE) using deep learning in transesophageal echocardiography (TEE). The aim of this study was clinical validation of auto-MAPSE in patients with heart disease. Methods and results TEE recordings were collected from 185 consecutive patients without selection on image quality. Deep learning-based auto-MAPSE was trained and optimized from 105 patient recordings. We assessed auto-MAPSE feasibility, a
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Holmstrom, V., E. Smistad, J. F. Grue, et al. "Deep learning in echocardiography: Fully automated B-mode MAPSE measurements in real-time." European Heart Journal - Cardiovascular Imaging 26, Supplement_1 (2025). https://doi.org/10.1093/ehjci/jeae333.071.

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Abstract Background Accurate quantification of left ventricular (LV) systolic function is crucial in echocardiography. LV Ejection Fraction (LV EF) and LV Global Longitudinal Strain (LV GLS), rely on clear delineation of the endocardial border, limiting their utility in patients with suboptimal acoustic windows. In contrast, Mitral Annular Plane Systolic Excursion (MAPSE) requires only the visualization of the mitral annulus with its strong acoustic reflections, offering near-perfect feasibility. However, conventional M-mode MAPSE is angle-dependent and prone to errors due to out-of-line movem
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Wang, Yong-Huai, Lu Sun, Shi-Wen Li, et al. "Normal Reference Values for Mitral Annular Plane Systolic Excursion by M-mode and Speckle-Tracking Echocardiography: A Prospective, Multicenter, Population-Based Study." European Heart Journal - Cardiovascular Imaging, August 2, 2023. http://dx.doi.org/10.1093/ehjci/jead187.

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Abstract Aims Mitral annular plane systolic excursion (MAPSE) is a simple and reliable index for evaluating left ventricular (LV) systolic function, particularly in patients with poor image quality; however, the lack of reference values limits its widespread use. This study aimed to establish the normal ranges for MAPSE measured using motion mode (M-mode) and two-dimensional speckle-tracking echocardiography (2D-STE) and to explore its principal determinants. Methods and results This multicenter, prospective, cross-sectional study included 1,952 healthy participants (840 men [43%]; age range,
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Balasubramaniyan, Jayanti Venkata, Ashutosh Prasad Tripathi, and J. S. Satyanarayana Murthy. "Mitral Annular Plane Systolic Excursion (MAPSE) as a Simple Index for Assessing Left Ventricular Function: An Observational Study." Journal of Pharmaceutical Research International, December 17, 2021, 163–70. http://dx.doi.org/10.9734/jpri/2021/v33i59b34366.

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Background: Mitral annular plane systolic excursion (MAPSE) has been proposed as a parameter for assessing left ventricular function. The assessment of LVF has major diagnostic and prognostic implications in patients with cardiovascular diseases. LVF is measured by Left Ventricular Ejection Fraction, however the accuracy of LVEF estimation by two dimensional echocardiography is limited especially in patients with poor image quality. Mitral annular plane systolic excursion (MAPSE) measurement predicts left ventricular function even in conditions with suboptimal echo window.
 Objective: To
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Lindow, Thomas, Hande Oktay Tureli, Charlotte Eklund Gustafsson, et al. "Mitral annular plane systolic excursion to left atrial volume ratio – a strainless relation with left ventricular filling pressures." International Journal of Cardiovascular Imaging, May 9, 2025. https://doi.org/10.1007/s10554-025-03413-x.

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Abstract Left atrial reservoir strain (LASr) offers diagnostic and prognostic value in patients with heart failure. However, LASr may be technically challenging and is not available to all clinical echocardiographers. Since LASr is a consequence of left atrial (LA) stretch during apical descent of the mitral annulus, we hypothesized that a ratio between mitral annular plane systolic excursion (MAPSE) and LA volume (LAV) may offer similar diagnostic value as LASr. We aimed to investigate the relationship between MAPSE/LAV and LASr and evaluate the diagnostic performance of MAPSE/LAV to identify
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Moderato, L., S. M. Binno, G. Pastorini, et al. "P1555 Delta mapse: an easy-to-use tool to evaluate coronary artery stenosis during dypiridamole pharmacological stress echocardiography." European Heart Journal - Cardiovascular Imaging 21, Supplement_1 (2020). http://dx.doi.org/10.1093/ehjci/jez319.976.

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Abstract Background Dypiridamol stress echocardiography (DSE) is an important tool for detecting reversible ischemia in patients with suspected coronary artery disease (CAD); nonetheless the results of the test are related to visualization of wall motion abnormalities, moderately operator-dependent, and left anterior descending (LAD) artery reserve, resulting in a moderate sensibility and specificity. Aim of our study was to evaluate whether an an easy-to-use parameter like mitral annular plane systolic excursion (MAPSE) could be useful to identify CAD during DSE. Methods We prospectively enro
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Moderato, L., S. Binno, G. Rusticali, et al. "Mitral anular plane excursion predicts coronary stenosis during stress echocardiography with dipyridamole." European Heart Journal - Cardiovascular Imaging 22, Supplement_1 (2021). http://dx.doi.org/10.1093/ehjci/jeaa356.198.

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Abstract Funding Acknowledgements Type of funding sources: None. Background Dipyridamole stress echocardiography (DSE) is an important tool for detecting reversible ischemia in patients with suspected coronary artery disease (CAD); nonetheless, the results of the test are related to wall motion abnormalities, moderately operator-dependent, and left anterior descending (LAD) artery reserve, resulting in a moderate sensibility and specificity. Purpose Aim Of our study was to evaluate whether an easy-to-use parameter like mitral annular plane systolic excursion (MAPSE) could be useful to identify
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Parhi, Deepak Kumar, and Kumar Gaurav Behera. "MITRAL ANNULAR PLANE SYSTOLIC EXCURSION-DERIVED FORMULA TO CALCULATE THE EJECTION FRACTION: A SIMPLE, EASY AND RAPID ECHOCARDIOGRAPHY PARAMETER TO ASSES LEFT VENTRICLE SYSTOLIC DYSFUNCTION." INDIAN JOURNAL OF APPLIED RESEARCH, April 1, 2021, 54–56. http://dx.doi.org/10.36106/ijar/2914485.

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Aims & Objectives - MAPSE DERIVED EJECTION FRACTION CAN BE USED AS AN ALTERNATIVE TO THE CONVENTIONAL ECHOCARDIORAPHIC MEASUREMENTS OF EJECION FRACTION IN EVERY DAY CLINICAL PRACTICE WITH PATIENTS WITH LV SYSTOLIC DYSFUNTION & VALIDATION OF MITRAL ANNULAR PLANE SYSTOLIC EXCURSION DERIVED FORMULA TO CALCULATE THE EJECTION FRACTION IN PATIENTS WITH LV SYSTOLIC DYSFUNCTION EF=4.8XMAPSE(mm)+5.8 in adult male & 4.2X MAPSE(mm)+20 in adult female. Our study is Material and Methodobservational, prospective study with cross sectional data collection done in a period of nov 2018 to nov 2019,
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Baig, Akif Ahamad, Rajendra Betham, and Srikanth Nathani. "Mitral Annulus Pre-Systolic Excursion (MAPSE) Versus Modified Simpson’s Method for Ejection Fraction Estimation in Patients with Acute Coronary Syndrome." Indian Journal of Cardiovascular Disease in Women, April 27, 2024, 1–7. http://dx.doi.org/10.25259/ijcdw_53_2023.

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Objectives: Evaluating left ventricle (LV) systolic function is pivotal in cardiac assessment, primarily relying on the left ventricular ejection fraction (LVEF) calculated through the modified Simpson’s method. However, challenges arise in accurately determining LVEF, especially in patients with acute coronary syndrome, where difficulty in visualizing the blood tissue interface can lead to inaccuracies. Mitral annular plane systolic excursion (MAPSE), which evaluates longitudinal function of LV has shown promise in detecting subtle myocardial abnormalities, particularly in patients with prese
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Ker, J. "Walking in a straight line–the early detection of cardiomyopathy by the general physician." European Heart Journal 42, Supplement_1 (2021). http://dx.doi.org/10.1093/eurheartj/ehab724.0718.

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Abstract Introduction The orientation of muscle fibers in the left ventricle is sophisticated. This peculiar orientation causes the left ventricle to contract in three directions–longitudinal, radial and circumferential. Normal myocardial mechanics is essential for systolic and diastolic function. For the clinician an impairment in longitudinal function is of utmost importance, as it has been shown to be an early marker of left ventricular dysfunction, be that systolic or diastolic. Longitudinal function of the left ventricle can be quantified with tissue velocity imaging (TVI), mitral annular
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Stoylen, A., H. E. Molmen, and H. E. Dalen. "P1744 Motion and velocity of the different parts of the AV plane. Relation to site and wall length." European Heart Journal - Cardiovascular Imaging 21, Supplement_1 (2020). http://dx.doi.org/10.1093/ehjci/jez319.1104.

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Abstract Background Displacement (MAPSE) and peak systolic velocity (S") of the various parts of the mitral annulus differ. Also, both indices are higher in the right ventricular free wall. We aimed to investigate the relations between wall motion, wall lengths and sites in the left ventricle, as well as comparing to the right ventricle to assess the influence on systolic deformation of the AV-plane. Methods The HUNT study examined 1266 subjects without evidence of heart disease from a mixed urban/rural population of North Trøndelag county, S", linear diastolic left ventricular annulus to apex
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Cirin, L., C. T. Luca, D. Gaita, et al. "LV systolic function assessment in conventional cardiac pacing: a simple and forgotten parameter - MAPSE." Europace 26, Supplement_1 (2024). http://dx.doi.org/10.1093/europace/euae102.414.

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Abstract Background Mitral annular plane systolic excursion (MAPSE) was a widely used M-mode echocardiographic marker of left ventricular longitudinal systolic function. On the other hand, right ventricle (RV) apical pacing is associated with left ventricle (LV) dysfunction development due to dysynchronous activation, while non-apical pacing may provide a more physiological LV activation. The aim of this study is to ascertain the clinical usefulness of MAPSE in the assessment of LV contractile function in patients with permanent RV pacing. Methods Consecutive patients with indication for perma
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Aveleli, Anudeep, Ashok G, and Gnanaguru Durairaj. "ASSESSMENT OF LEFT VENTRICULAR FUNCTION USING MITRAL ANNULAR PLANE SYSTOLIC EXCURSION/LEFT VENTRICULAR LENGTH AND GLOBAL LONGITUDINAL STRAIN IN HEART FAILURE PATIENTS." GLOBAL JOURNAL FOR RESEARCH ANALYSIS, January 15, 2025, 71–73. https://doi.org/10.36106/gjra/7304270.

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Introduction: Evaluation of ventricular function especially longitudinal parameters like Mitral annular plane excursion, holds signicant importance in the timely identication of myocardial dysfunction. While mitral annular plane systolic excursion (MAPSE) provides a straightforward means of measuring and quantifying the LV function, its reliability can exhibit variations among individuals with heart failure, dilated hearts, and across genders. Therefore, considering the ratio of MAPSE to left ventricular diastolic length as a potential parameter for evaluating LV function in heart failure pa
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Panovský, Roman, Martin Pešl, Jan Máchal, et al. "Quantitative assessment of left ventricular longitudinal function and myocardial deformation in Duchenne muscular dystrophy patients." Orphanet Journal of Rare Diseases 16, no. 1 (2021). http://dx.doi.org/10.1186/s13023-021-01704-9.

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Abstract Background Duchenne muscular dystrophy (DMD) manifests in males mainly by skeletal muscle impairment, but also by cardiac dysfunction. The assessment of the early phases of cardiac involvement using echocardiography is often very difficult to perform in these patients. The aim of the study was to use cardiac magnetic resonance (CMR) strain analysis and mitral annular plane systolic excursion (MAPSE) in the detection of early left ventricular (LV) dysfunction in DMD patients. Methods and results In total, 51 male DMD patients and 18 matched controls were examined by CMR. MAPSE measurem
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Al-Amir, Nashwa Abed Mohamed, Mohamed Shawky El-Shishtawy, Ahmed Hossam Ahmed Mowafy, Akram Mohamed Abdel Bary, and Khaled Hussein Magdy. "Mitral Annular Plane Systolic Excursion (MAPSE) as a Predictor of Weaning Failure in Mechanically Ventilated Patients." International Journal of Chemical and Biochemical Sciences 25, no. 19 (2024). http://dx.doi.org/10.62877/9-ijcbs-24-25-19-9.

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Weaning failure is multifactorial in nature; it can result from diaphragmatic dysfunction, excess mechanical load, weaning-induced cardiovascular dysfunction, or a reduced ability to clear secretions. To investigate mitral annular plane systolic excursion (MAPSE) by using M-mode echocardiography as a predictor of weaning failure and its relation to length of intensive care unit stay, and to hospital mortality, and correlation of MAPSE with APACHE II and SOFA scores as predictors of outcome. This was a prospective observational cohort study conducted on 50 patients admitted to Critical Care Med
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Avnet, Hagai, Samantha Thomas, Anna Erenbourg, Simcha Yagel, and Alec Welsh. "Evaluating fetal tricuspid and mitral annular plane systolic excursion (TAPSE and MAPSE) using spatiotemporal image correlation (STIC) M-mode." Journal of Perinatal Medicine, May 10, 2024. http://dx.doi.org/10.1515/jpm-2023-0423.

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Abstract Objectives This study aimed to evaluate the feasibility and reliability of tricuspid and mitral annular plane systolic excursion measurements (TAPSE and MAPSE) applying M-mode Spatiotemporal Image Correlation (STIC) technology in low-risk pregnancies. Methods An initial retrospective pilot study was carried out to assess repeatability, followed by a larger mixed cross-sectional and prospective longitudinal study, both evaluating low-risk singleton pregnancies between 22+6 and 39+1 weeks. As only annuli capture was necessary, STIC acquisition parameters were set to the minimum volume a
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Rangarajan, Vibhav, Satish J. Chacko, Nikhil Jariwala, Simone Romano, Jaehoon Chung, and Afshin Farzaneh-Far. "Abstract 15856: Left Ventricular Longitudinal Contractility Measured During Routine Cine-cardiac Magnetic Resonance Imaging is an Independent Predictor of Adverse Cardiac Events." Circulation 132, suppl_3 (2015). http://dx.doi.org/10.1161/circ.132.suppl_3.15856.

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Background: Left ventricular systole involves coordinated contraction of longitudinal, circumferential, and radial myocardial fibers. Longitudinal fiber dysfunction appears to be an early marker for a number of pathological states. We hypothesized that reduced mitral annular plane systolic excursion (MAPSE) measured during cine-Cardiac Magnetic Resonance (CMR) imaging reflects changes in longitudinal fiber function and may be an early marker for adverse cardiovascular outcomes. Methods: 400 consecutive patients with known or suspected coronary artery disease undergoing CMR were prospectively e
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Baig, Akif Ahamad, Rajendra Betham, Nathani Srikanth, Boochi Babu Mannuva, and Jagadeesh Chandra Bose Yannam. "Assessment of Left Ventricular Function using Mitral Annular Plane Systolic Excursion and its Validation with Conventional Methods and Global Longitudinal Strain using Echocardiography in Patients with Coronary Artery Disease." Indian Journal of Cardiovascular Disease in Women, May 2, 2025, 1–6. https://doi.org/10.25259/ijcdw_18_2024.

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Objectives The evaluation of left ventricular (LV) function is crucial in assessing myocardial health, with LV ejection fraction (LVEF) serving as a key metric. For LVEF measurement, two-dimensional echocardiography is frequently used, usually with a modified Simpson’s approach. Alternative methods, such as mitral annular plane systolic excursion (MAPSE) and global longitudinal strain (GLS), provide more information about cardiac function, particularly in difficult clinical situations. This study compares MAPSE and GLS with conventional methods in an effort to determine the efficacy of these m
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Johansson Blixt, Patrik, Michelle S. Chew, Rasmus Åhman, et al. "Left ventricular longitudinal wall fractional shortening accurately predicts longitudinal strain in critically ill patients with septic shock." Annals of Intensive Care 11, no. 1 (2021). http://dx.doi.org/10.1186/s13613-021-00840-6.

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Abstract Background Left ventricular longitudinal strain (LVLS) may be a sensitive indicator of left ventricular (LV) systolic function in patients with sepsis, but is dependent on high image quality and analysis software. Mitral annular plane systolic excursion (MAPSE) and the novel left ventricular longitudinal wall fractional shortening (LV-LWFS) are bedside echocardiographic indicators of LV systolic function that are less dependent on image quality. Both are sparsely investigated in the critically ill population, and may potentially be used as surrogates for LVLS. We assessed if LVLS may
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