Relevant bibliographies by topics / Marcatori biologici

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Marcatori biologici'

Author: Grafiati
Published: 9 March 2023
Last updated: 10 March 2023

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Journal articles on the topic "Marcatori biologici"

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Ferolla, Piero, Antongiulio Faggiano, Gabriella Angeletti, Fausto Santeusanio, Gaetano Lombardi, and Annamaria Colao. "La caratterizzazione biologica dei NET: ruolo diagnostico e prognostico dei marcatori neuroendocrini." L'Endocrinologo 7, no. 2 (2006): 83–92. http://dx.doi.org/10.1007/bf03344537.

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Beltramello, A., G. Puppini, R. Caudana, et al. "Meningiomi endocranici aggressivi, quadri clinici-RM." Rivista di Neuroradiologia 6, no. 4 (1993): 439–43. http://dx.doi.org/10.1177/197140099300600409.

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Il guadagno diagnostico offerto dalla RM nella diagnosi dei meningiomi intra-cranici risiede nella precisa localizzazione della lesione all'interno del cranio e nella definizione dei suoi rapporti con le adiacenti strutture, in particolare arterie e vene. Le caratteristiche morfo-strutturali possono essere comparate con gli aspetti istologici ed operatori in modo da identificare possibili caratteri clinico-radiologici associati ad un comportamento biologico ed evolutivo diverso da quello usualmente benigno dei meningiomi non aggressivi (MNA). 64 meningiomi intra-cranici sono stati valutati ret
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Crepaldi, G., M. Voci, M. Saracco, et al. "AB0241 PREVALENCE OF ANXIOUS SYMPTOMS AND DEPRESSION IN A SAMPLE OF PATIENTS WITH RHEUMATOID ARTHRITIS (RA) AND OTHER CHRONIC RHEUMATIC DISEASES." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1420.2–1421. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2471.

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Background:Clinical practice with patients suffering from chronic diseases highlights the presence of psychological symptoms of discomfort fed by biological and non-biological mechanisms linked to disease and treatment. In rheumatic diseases, literature detects the presence of anxious symptoms and depressed mood of clinical and sub-clinical importance with a multifactorial genesis1.Objectives:To detect the impact on the state of health of anxious symptoms and depressed mood in a population suffering from RA and other rheumatic diseases in order to implement the effectiveness of psychological i
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Mizera, Mikolaj, Anna Sanecka-Duin, Maciej Jasiński, et al. "827 Streamlining design of safe and effective TCR therapies with AI." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (2021): A866. http://dx.doi.org/10.1136/jitc-2021-sitc2021.827.

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BackgroundAdoptive cell therapies with T lymphocytes expressing engineered T cell receptors (TCRs) are one of the most promising approaches to cancer therapy.1 However, the experimentally driven development of novel TCR therapies is limited by the enormous biological variability of peptide:Human Leukocyte Antigen:TCR (pHLA:TCR) complexes. The in silico methods hold the promise to streamline the discovery of novel TCR therapies by reducing costs and time of laboratory research. In particular, the prediction of TCR binding to a target antigen, as well as the prediction of TCR off-target toxicity
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Dissertations / Theses on the topic "Marcatori biologici"

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Sista, Maria Teresa <1979&gt. "Studio di marcatori biologici prognostici nel linfoma di Hodgkin." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amsdottorato.unibo.it/2950/1/Sista_MariaTeresa_Studio_di_marcatori_biologici_prognostici_nel_linfoma_di_Hodgkin.pdf.

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Recent reports showed that early-interim PET-scan is the only tool predicting treatment outcome in advanced-stage classical Hodgkin lymphoma (asCHL). We evaluated the prognostic impact of a series of immunohistochemical markers, mentioned in literature as prognostic factors, on tissue microarrays assembled from biopsies of 220 patients: STAT1, SAP, TOP2A, PCNA and CD20, both in neoplastic (HRSC) and microenvironment cells (MC); RRM2, MAD2, CDC2, BCL2, P53, BCL11A and EBER in HRSC; ALDH1A1, TIA-1, granzyme B, perforin, FOXP3, and PD-1 in MC. All patients had been treated with standard ABVD ± Rx
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Sista, Maria Teresa <1979&gt. "Studio di marcatori biologici prognostici nel linfoma di Hodgkin." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amsdottorato.unibo.it/2950/.

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Recent reports showed that early-interim PET-scan is the only tool predicting treatment outcome in advanced-stage classical Hodgkin lymphoma (asCHL). We evaluated the prognostic impact of a series of immunohistochemical markers, mentioned in literature as prognostic factors, on tissue microarrays assembled from biopsies of 220 patients: STAT1, SAP, TOP2A, PCNA and CD20, both in neoplastic (HRSC) and microenvironment cells (MC); RRM2, MAD2, CDC2, BCL2, P53, BCL11A and EBER in HRSC; ALDH1A1, TIA-1, granzyme B, perforin, FOXP3, and PD-1 in MC. All patients had been treated with standard ABVD ± Rx
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DUGNANI, ERICA. "Identificazione e validazione di potenziali marcatori biologici nell’adenocarcinoma duttale del pancreas." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2015. http://hdl.handle.net/10281/76153.

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Introduzione. L’adenocarcinoma duttale (PDAC) rappresenta circa l’85% delle neoplasie maligne pancreatiche. È un tipo di neoplasia molto aggressiva e ha prognosi infausta. Il PDAC è una malattia con una elevata mortalità, spesso diagnosticata in uno stadio avanzato per il quale esistono poche e inefficaci terapie. L’alta incidenza di ricadute locali unita alla precoce metastatizzazione sono le caratteristiche cliniche più tipiche di questo tumore. Inoltre la nota resistenza del tumore alla chemio e alla radioterapia limita l’efficacia di questi approcci terapeutici. Scopo. Identificare e vali
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GIANNATEMPO, GIOVANNI. "Ricerca di marcatori molecolari del carcinoma del cavo orale nei fluidi biologici, quali sangue e saliva, a fini di diagnosi precoce e prognosi." Doctoral thesis, Università di Foggia, 2016. http://hdl.handle.net/11369/363213.

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Il carcinoma a cellule squamose è il più frequente tumore maligno del cavo orale (1, 2) ed è la sesta causa di mortalità legata a tumore nel mondo. Esso è caratterizzato da un basso tasso di sopravvivenza, dovuto principalmente alla diagnosi tardiva ed all’elevata frequenza di recidive e/o metastasi. Nel mio studio si è pertanto cercato di individuare dei marcatori a livello salivare che potessero facilitare la diagnosi precoce, utilizzando la metodica SELDI, e verificare le già note potenzialità della Survivina come marcatore biologico, al fine di rendere quindi possibile, in futuro, l’
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Gasparri, Roberto <1968&gt. "Tumori primitivi multipli del polmone. Profilo clinico e biologico in pazienti affetti da neoplasie polmonari multiple. Analisi di elementi clinici e marcatori biologici come possibili fattori di differenziazione dei tumori polmonari multipli." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3655/1/Gasparri-roberto-Tesi.pdf.

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Background: MPLC represents a diagnostic challenge. Topic of the discussion is how to distinguish these patients as a metastatic or a multifocal disease. While in case of the different histology there are less doubt on the opposite in case of same histology is mandatory to investigate on other clinical features to rule out this question. Matherials and Methods: A retrospective review identified all patients treated surgically for a presumed diagnosis of SPLC. Pre-operative staging was obtained with Total CT scan and fluoro-deoxy positron emission tomography and mediastinoscopy. Patients with
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Gasparri, Roberto <1968&gt. "Tumori primitivi multipli del polmone. Profilo clinico e biologico in pazienti affetti da neoplasie polmonari multiple. Analisi di elementi clinici e marcatori biologici come possibili fattori di differenziazione dei tumori polmonari multipli." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3655/.

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Background: MPLC represents a diagnostic challenge. Topic of the discussion is how to distinguish these patients as a metastatic or a multifocal disease. While in case of the different histology there are less doubt on the opposite in case of same histology is mandatory to investigate on other clinical features to rule out this question. Matherials and Methods: A retrospective review identified all patients treated surgically for a presumed diagnosis of SPLC. Pre-operative staging was obtained with Total CT scan and fluoro-deoxy positron emission tomography and mediastinoscopy. Patients with
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Germani, Giacomo. "Predicting acute cellular rejection after liver transplantation: form liver function test to immune monitoring." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3426180.

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In recent years, the main end point of immunosuppressive therapy after liver transplantation has moved from the prevention of acute cellular rejection (ACR) toward the preservation of long-term graft function and prevention of immunosuppression-related side effects. This approach requires an optimal management of immunosuppressive therapy according to patient risk factors. However, the concentration of immunosuppressive drugs in the serum of patients, which is generally used as a surrogate for the level of immunosuppression, does not provide information about the magnitude of suppression of th
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CAPUZZI, ENRICO. "RECENT SUICIDE ATTEMPTS AND SERUM LIPID PROFILE IN SUBJECTS WITH MENTAL DISORDERS: A CROSS-SECTIONAL STUDY." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2019. http://hdl.handle.net/10281/241289.

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Introduzione: I soggetti con disturbi mentali hanno un rischio più elevato di comportamenti suicidari rispetto alla popolazione generale. Pertanto, ad oggi, i ricercatori hanno studiato alcuni marcatori biologici potenzialmente correlati al suicidio. Nonostante molti studi abbiano riportato una possibile correlazione tra bassi livelli ematici di lipidi e tentativo di suicidio, sono emersi risultati contrastanti. Scopo del lavoro: Abbiamo studiato se il colesterolo totale , il colesterolo LDL e i trigliceridi ematici siano associati a recenti tentativi di suicidio in soggetti con diversi distu
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Elmakky, Amira <1982&gt. "Identificazione e dosaggio di marcatori molecolari dell'endometriosi nel sangue periferico." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3889/1/ELMAKKY__AMIRA_tesi.pdf.

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Purpose: to quantify the mRNA levels of MMP-3, MMP-9, VEGF and Survivin in peripheral blood and the serum levels of CA-125, Ca19-9 in women with and without endometriosis and to investigate the performance of these markers to differentiate between deep and ovarian endometriosis. Methods: a case controls study enrolled a series of 60 patients. Twenty controls have been matched with 20 cases of ovarian and 20 cases of deep endometriosis. Univariable and multivariable performance of serum CA125 and CA19-9, mRNA for Survivin, MMP9, MMP3 and VEGF genes have been evaluated by means of ROC curves an
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Elmakky, Amira <1982&gt. "Identificazione e dosaggio di marcatori molecolari dell'endometriosi nel sangue periferico." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3889/.

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Purpose: to quantify the mRNA levels of MMP-3, MMP-9, VEGF and Survivin in peripheral blood and the serum levels of CA-125, Ca19-9 in women with and without endometriosis and to investigate the performance of these markers to differentiate between deep and ovarian endometriosis. Methods: a case controls study enrolled a series of 60 patients. Twenty controls have been matched with 20 cases of ovarian and 20 cases of deep endometriosis. Univariable and multivariable performance of serum CA125 and CA19-9, mRNA for Survivin, MMP9, MMP3 and VEGF genes have been evaluated by means of ROC curves an
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Book chapters on the topic "Marcatori biologici"

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Marcatili, Paolo, and Anna Tramontano. "Network Cleansing." In Biological Data Mining in Protein Interaction Networks. IGI Global, 2009. http://dx.doi.org/10.4018/978-1-60566-398-2.ch006.

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This chapter provides an overview of the current computational methods for PPI network cleansing. The authors first present the issue of identifying reliable PPIs from noisy and incomplete experimental data. Next, they address the questions of which are the expected results of the different experimental studies, of what can be defined as true interactions, of which kind of data are to be integrated in assigning reliability levels to PPIs and which gold standard should the authors use in training and testing PPI filtering methods. Finally, Marcatili and Tramontano describe the state of the art in the field, presenting the different classes of algorithms and comparing their results. The aim of the chapter is to guide the reader in the choice of the most convenient methods, experiments and integrative data and to underline the most common biases and errors to obtain a portrait of PINs which is not only reliable but as well able to correctly retrieve the biological information contained in such data.
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