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Relevant bibliographies by topics / Marjolin, ulcere

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Academic literature on the topic 'Marjolin, ulcere'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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Journal articles on the topic "Marjolin, ulcere"

1

Yesilada, Aysin Karasoy, Kamuran Zeynep Sevim, Deniz Özgur Sucu, et al. "Marjolin Ulcer: Clinical Experience with 34 Patients over 15 Years." Journal of Cutaneous Medicine and Surgery 17, no. 6 (2013): 404–9. http://dx.doi.org/10.2310/7750.2013.13016.

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Background: Malignancies that arise from scars are referred to as Marjolin ulcers. The association between chronic ulcers and squamous cell carcinomas is well established. There are many case reports in the literature regarding Marjolin ulcer; however, randomized controlled clinical series that describe a thorough evaluation of these patients are rarely encountered. Objective: We present our clinic's 15 years of experience with 34 Marjolin ulcer patients and their treatment modalities. Methods: A retrospective analysis of 302 squamous cell carcinoma patients who were treated in the plastic surgery department between 1997 and 2011 was performed. Thirty-four (10.3%) histopathologically confirmed Marjolin ulcer patients were further analyzed. Results: Although burn scars represented 77% of the patients in the present study, unstable scars that formed following traffic accidents and fistula tracts are also among the commonly encountered etiologies. Based on our observations, squamous cell carcinoma, in addition to malignant melanoma and verrucous carcinoma, is frequently observed in cases of Marjolin ulcers. Conclusion: If the goal is to eradicate this clinical entity, all of the chronic ulcers that fail to heal require biopsies at regular intervals. Large excisional margins, lymphadenectomies in cases of palpable lymph nodes, and a well-defined oncology protocol are all essential in treating Marjolin ulcer.

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Abdi, Mohamed A., Michael Yan, and Timothy P. Hanna. "Systematic Review of Modern Case Series of Squamous Cell Cancer Arising in a Chronic Ulcer (Marjolin's Ulcer) of the Skin." JCO Global Oncology, no. 6 (September 2020): 809–18. http://dx.doi.org/10.1200/go.20.00094.

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PURPOSE Marjolin's ulcer is an aggressive cutaneous malignancy that arises in chronic nonhealing wounds. A review of modern series describing Marjolin's ulcer would be helpful in defining optimal management strategies and expected outcomes. METHODS A systematic review was performed on October 18, 2018, by querying Medline and EMBASE. Key inclusion criteria were as follows: human studies, English language, published in 2000 or later, > 10 patients, and at least 80% of the patients having squamous cell carcinoma (SCC) histology. RESULTS There were 599 patients in 14 case series from 10 countries; 82% of patients were from low-income and middle-income countries, and 48% were women. Overall, 65% of the ulcers were preceded by burns. Mean latency ranged from 11 years to 41 years (median, 28 years). Lower extremities were the most common site (62%). Differentiation was reported as well differentiated (64%), moderately differentiated (27%), or poorly differentiated (9%). Almost one third of cases were clinically node positive, though only 7% of all cases (24 of 334) were confirmed to be pathologically involved. Distant metastasis rates were reported in only 7 series, with median rate of 5% (range, 0%-27%). The main treatment modality was surgical excision (71%), followed by amputation (24%), primary radiotherapy (2%), and chemotherapy (< 1%). Outcomes data varied in content and quality. Mortality rates were 12%, 24%, and 37% in the three series reporting between 2 and 3 years of follow-up. CONCLUSION Marjolin's ulcer with SCC histology is an aggressive cancer with a notable potential for lymph node metastasis and distant metastasis. Comprehensive staging is recommended, with management optimally having a multidisciplinary context. Low- and middle-income countries are overrepresented in reports of Marjolin’s ulcer, and there may be opportunities for prevention and early detection.

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Villalba, Willian, Juan B. Ortellado, Romina Duarte, and Miguel Campuzano. "MARJOLIN'S ULCER: A CASE REPORT." CIRUGIA PARAGUAYA 40, no. 2 (2016): 38–40. http://dx.doi.org/10.18004/sopaci.noviembre.38-40.

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Chaturvedi, Gaurav, Ashish Kumar Gupta, Saikat Das, Amish Jayantilal Gohil, and Shashank Lamba. "Marjolin Ulcer." Annals of Plastic Surgery 83, no. 5 (2019): 518–22. http://dx.doi.org/10.1097/sap.0000000000001995.

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O’Malley, John T., Candace Schoppe, Sameera Husain, and Marc E. Grossman. "Squamous Cell Carcinoma (Marjolin’s Ulcer) Arising in a Sacral Decubitus Ulcer Resulting in Humoral Hypercalcemia of Malignancy." Case Reports in Medicine 2014 (2014): 1–3. http://dx.doi.org/10.1155/2014/715809.

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Long-standing burns, fissures, and ulcers that undergo malignant transformation into a variety of malignancies, including squamous cell carcinoma, is commonly referred to as a Marjolin’s ulcer. It is well recognized that squamous cell carcinomas of the lung and esophagus can cause humoral hypercalcemia of malignancy secondary to paraneoplastic secretion of parathyroid hormone-related peptide. However, it is extremely rare for a squamous cell carcinoma developing in a sacral decubitus ulcer to cause humoral hypercalcemia of malignancy. We describe the first case of a patient found to have elevated serum levels of parathyroid hormone related peptide related to his Marjolin’s ulcer. A 45-year-old African American man with T6 paraplegia and a sacral decubitus ulcer present for 20 years was admitted for hypercalcemia of unclear etiology. He was subsequently found to have elevated parathyroid hormone related peptide and an excisional biopsy from the ulcer showed invasive squamous cell carcinoma suggestive of humoral hypercalcemia of malignancy. The patient ultimately succumbed to sepsis while receiving chemotherapy for his metastatic squamous cell carcinoma. Humoral hypercalcemia of malignancy is a rare and likely underrecognized complication that can occur in a Marjolin’s ulcer.

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Bai, Ming, Xiao Long, and Ru Zhao. "Acute Marjolin Ulcers." Annals of Plastic Surgery 73, no. 6 (2014): 723. http://dx.doi.org/10.1097/sap.0000000000000305.

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Chang, Jessica B., Theodore A. Kung, and Paul S. Cederna. "Acute Marjolin Ulcers." Annals of Plastic Surgery 73, no. 6 (2014): 723–24. http://dx.doi.org/10.1097/sap.0000000000000323.

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Macedo, Francisco, Sandra Macedo, Filipa Drumond, and Miguel Pestana. "Úlcera de Marjolin." Acta Médica Portuguesa 29, no. 7-8 (2016): 492. http://dx.doi.org/10.20344/amp.6870.

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Ali, Hyder, Yusra Afzal, Syfyan Ahmed, Mujtuba Pervaiz, Masood Hussain Rao, and Syed Muhammad Ali. "MARJOLIN’S ULCER AND BURN SCARS." Professional Medical Journal 25, no. 06 (2018): 799–804. http://dx.doi.org/10.29309/tpmj/2018.25.06.261.

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Background: Marjolin’s ulcer (MU) represents malignant degeneration thattypically ensues over a period of time in the post-burned lesions and scars or any other chronicwound. The worldwide incidence of MUs in such lesions is reported to be 0.77%-2%. Objectives:To determine the frequency of malignancy in post burn scars. Study Design: Descriptive, crosssectional. Place & Setting: Department of Plastic & Reconstructive Surgery, Dow Universityof Health Sciences & Dr Ruth KM Pfau Civil Hospital Karachi. Duration: December 2014 toNovember 2017. Materials & Methods: A selection criterion was defined and via non probabilityconsecutive sampling. Sample Size: 80 patients. Results: The mean age of the patients was48.6 ± 9.2years with range (30 to 60 years). The mean duration of scars was found in ourstudy to be 20.4+5.1 years. Out of 80 patients, 33 (41%) were male and 47 (59%) were female.Malignancy was recorded in 66(82.5%) patients with post burn scar. The most common typeof malignancy was squamous cell carcinoma in 27 patients (33%). Conclusion: A high indexof suspicion is required when dealing with chronic non-healing ulcers. In our environmentearly recognition and aggressive treatment of Marjolin’s ulcers and close follow-up are vital forprevention and also to improve outcome.

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Tiftikcioglu, Yigit Ozer, Cuneyt Ozek, Ufuk Bilkay, Ali Uckan, and Yalcin Akin. "Marjolin Ulcers Arising on Extremities." Annals of Plastic Surgery 64, no. 3 (2010): 318–20. http://dx.doi.org/10.1097/sap.0b013e3181a73064.

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Dissertations / Theses on the topic "Marjolin, ulcere"

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HERBERT, VINCENT. "Dégénérescence cancéreuse des cicatrices instables : ulcères de Marjolin : à propos de 16 observations." Toulouse 3, 1992. http://www.theses.fr/1992TOU31050.

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Book chapters on the topic "Marjolin, ulcere"

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Menendez, Moises, and Christopher Menendez. "Marjolin’s Ulcer." In Chronic Wounds, Wound Dressings and Wound Healing. Springer International Publishing, 2018. http://dx.doi.org/10.1007/15695_2017_94.

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"Marjolin ulcer." In Dermatology Therapy. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/3-540-29668-9_1737.

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Farne, Hugo, Edward Norris-Cervetto, and James Warbrick-Smith. "Leg ulcer." In Oxford Cases in Medicine and Surgery. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780198716228.003.0035.

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Venous ulcers account for by far the majority (about 70%), with mixed arterial/venous (about 10%) and arterial (about 10%) most of the remainder. Pressure ulcers have become increasingly common because of the increase in elderly, frail, and relatively immobile patients. The other causes are relatively rare with the exception of neuropathic ulcers in patients with diabetes mellitus. Note that many leg ulcers may have a multifactorial aetiology, i.e. they may involve more than one of the pathologies listed in Figure 29.1. The first thing is to ask about the ulcer. You should consider: • Is the ulcer painful? ■ Venous ulcers are caused by venous stasis in the leg and are thus less painful when elevated and drained of blood. However, only about 30% of venous ulcers are painful. ■ Arterial (atherosclerotic) ulcers are caused by ischaemia to the leg and are thus more painful when elevated and drained of blood. Patients often say the ulcers are painful enough to wake them up at night and that they obtain relief by lowering their leg over the side of the bed. ■ Neuropathic ulcers are caused by loss of sensation (which predisposes to constant trauma) and are thus not painful. ■ Pressure ulcers are caused by, as the name suggests, prolonged pressure on the affected site. They tend to be exquisitely tender but not necessarily painful if no pressure is being applied. • How long has the ulcer been there? ■ Venous ulcers are less painful and can therefore present late. They often have a long and recurring history. ■ Arterial ulcers tend to present relatively early because of pain. They often occur secondary to trivial trauma. ■ Neuropathic ulcers are associated with a loss of sensation and thus often present late. ■ Pressure ulcers can develop surprisingly rapidly (e.g. days in immobile patients if they are not turned regularly during their admission, even hours in patients who suffer a long lie following a fall), but can have a more indolent course depending on how much pressure is put on for how long. Thus the time course is not especially helpful. ■ A long history should arouse suspicion of a Marjolin ulcer, which only occurs in long-standing ulcers.

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"Marjolin's ulcer." In Dermatology Therapy. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/3-540-29668-9_1738.

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Ray, MD. "Post Burns Contracture And Marjolin Ulcer." In Gateway to Success in Surgery. Jaypee Brothers Medical Publishers (P) Ltd., 2012. http://dx.doi.org/10.5005/jp/books/11524_41.

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Conference papers on the topic "Marjolin, ulcere"

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Demehri, Shadmehr, Trevor J. Cunningham, Eva A. Hurst, Andras Schaffer, David M. Sheinbein, and Wayne M. Yokoyama. "Abstract A64: Chronic allergic contact dermatitis, A potent tumor promoter of Marjolin's ulcer." In Abstracts: AACR Special Conference: Tumor Immunology and Immunotherapy: A New Chapter; December 1-4, 2014; Orlando, FL. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/2326-6074.tumimm14-a64.

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