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Dissertations / Theses on the topic 'MARKERS OF DIAGNOSTIC THINKING'

Author: Grafiati

Published: 1 July 2021

Last updated: 29 July 2025

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1

Цыплакова, Е. С., та E. S. Tsyplakova. "Исследование профессионального мышления студентов-психологов : магистерская диссертация". Master's thesis, б. и, 2021. http://hdl.handle.net/10995/100001.

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Объектом исследования является профессиональное мышление студентов-психологов. Предметом исследования являлись предикторы развития диагностического мышления. Магистерская диссертация состоит из введения, трех глав, заключения, списка литературы (61 источник) и приложения, включающего в себя результаты методик (в баллах) и содержание теста. Объем магистерской диссертации 94 страниц, на которых размещены 1 рисунок и 5 таблиц. Во введении раскрывается актуальность проблемы исследования, разработанность проблематики, ставятся цель и задачи исследования, определяются объект и предмет исследования,

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2

Slyvka, N. O., I. A. Plesh, L. D. Boreiko, and Olena Viktorivna Makarova. "Diagnostic markers of hepatorenal syndrome." Thesis, Программа 99-ї підсумкової науковової конференції професорсько-викладацького персоналу Вищого державного навчального закладу України "Буковинський державний медичний університет" 12, 14, 19 лютого 2018 року, 2018. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/13765.

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3

Satterthwaite, Gemma. "Discovery of diagnostic markers for atherosclerosis." Thesis, University of Sheffield, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274961.

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4

Clark, Rachael Louise. "Diagnostic markers of infection, in chronic wounds." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/55725/.

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A complication associated with wound healing is wound infection. The diagnosis of infection in chronic wounds can be a difficult clinical decision. Signs and symptoms used to diagnose infection can often be masked by factors relating to the host, chronic inflammation and the tissue damage, associated with chronic wounds. This Study aimed to determine whether there is a measurable biochemical host response that could serve as potential biomarkers of chronic wound infection, providing an alternative diagnostic tool to aid the Clinician. An in vitro model further investigated the expression of ma

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5

Andreasen, Niels. "Search for reliable diagnostic markers for Alzheimer's disease /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4039-8/.

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6

Guimarães, Sa Correia Pedro. "Image Processing in Ophthalmology Towards Improved Diagnostic Markers." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3425860.

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The eye is a window to the outside world. It takes in light from the environment, converts it to electrical signals, and forwards it to the brain. In a similar manner it has been regarded as a window to our health. By imaging the eye we can visualize blood vessels and nerves noninvasively. Thus, ophthalmic imaging may allow us to diagnose and monitor both ocular and systemic diseases. The retina has been the main focus of this line of research. Nevertheless, within the eye other structures of interest exist. Blood vessels of the bulbar conjunctiva and nerve fibers from the corneal subbasal p

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7

Essack, Magbubah. "Transcription Regulation and Candidate Diagnostic Markers of Esophageal Cancer." Thesis, University of the Western Cape, 2009. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_5306_1267148426.

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<p>This thesis reports on the development of a novel comprehensive database (Dragon Database of Genes Implicated in Esophageal Cancer, DDEC) as an integrated knowledge database aimed at representing a gateway to esophageal cancer related data. More importantly, it illustrates how the biocurated genes in the database may represent a reliable starting point for divulging transcriptional regulation, diagnostic markers and the biology related to esophageal cancer.</p>

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8

Al-Khalili, Faris. "Coronary heart disease in women : diagnostic and prognostic markers /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4092-4/.

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9

BERZERO, GIULIA. "“MOLECULAR MARKERS IN DIFFUSE GLIOMAS: DIAGNOSTIC AND THERAPEUTIC TARGETS”." Doctoral thesis, Università degli studi di Pavia, 2020. http://hdl.handle.net/11571/1371676.

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Due to their capital diagnostic, prognostic and therapeutic implications, molecular markers have become essential for the management of patients with diffuse gliomas. Among them, IDH mutations have special importance, as they allow to classify diffuse gliomas, they are predictive of prolonged survival and increased sensitivity to alkylating agents and can be targeted by specific inhibitors. IDH-mutant diffuse gliomas deeply differ from IDH-wildtype diffuse gliomas in terms of molecular profile, prognosis and treatment, as different are the pathways of gliomagenesis and progression in the two g

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10

MEGHA, T., A. NERI, S. CARUSO, et al. "Traditional and new diagnostic and prognostic markers in breast cancer." Doctoral thesis, Università di Siena, 2017. http://hdl.handle.net/11365/1012970.

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Despite the constant progress on the understanding of the molecular bases of cancer, there is still the need to identify novel prognostic and predictive markers aimed at improving diagnosis and, at the same time, designing a more targeted therapeutic approach. For this to be achieved, we have to take into consideration the biological heterogeneity of each tumor that explains different responses to standard therapies harbored by different patients within the same tumor stage and histological type. Such a combined approach does not apply to improving classification and prognosis of breast c

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11

Zheng, Yingye. "Semiparametric methods for longitudinal diagnostic accuracy /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/9580.

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12

Nouzová, Eva. "Eye movements as diagnostic trait markers for adult major depressive disorder." Thesis, University of Aberdeen, 2016. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=230162.

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Diagnosis of Major Depressive Disorder (MDD) is currently symptom-based and no externally validated tests are available for routine use to confirm clinical diagnoses. Eye movement abnormalities in schizophrenia (SCZ) and bipolar disorder (BPAD) have been consistently reported and their potential as a biological trait marker highlighted. Only a limited amount of research has been conducted in MDD. Eye movement performance of MDD patients (n = 99; F:M = 55:44; Mdn age = 48) was investigated using picture free-viewing, smooth pursuit and fixation stability tasks and recorded using a non-invasive

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13

Dreesman, Alexandra. "Development and evaluation of new diagnostic markers of tuberculosis in children." Doctoral thesis, Universite Libre de Bruxelles, 2020. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/312223.

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Tuberculosis in the number one infectious cause of death worldwide, but remains underappreciated as a cause of mortality in children and difficult to diagnose. Diagnostic difficulties of TB in children are a consequence of the non-specific clinical presentation, the different spectrum of disease in children and the paucibacillary nature of disease making microbiological confirmation challenging in many cases. Moreover, existing immunodiagnostic tests have important limitations, especially with regard to childhood TB: they lack sensitivity to rule out TB, and are unable to offer discrimination

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14

Arko-Mensah, John. "Mycobacterial infection: Immune evasion, host susceptibility and immunological markers of diagnostic importance." Doctoral thesis, Stockholm University, Wenner-Gren Institute for Experimental Biology, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-8208.

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<p>IIn the first study, we investigated the functional implications of prolonged TLR signalling on IFN-γ mediated killing of mycobacteria by murine macrophages <i>in vitro</i>. TLR2, but not TLR4 ligation interfered with IFN-γ mediated killing of mycobacteria in macrophages. In terms of mechanisms, neither TNF nor nitric oxide (NO) production was significantly affected, and the refractoriness induced could be reversed with increasing amounts of IFN-γ In the second study, we aimed to identify immunological markers of diagnostic importance in both the respiratory tract and serum during pulmonary

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Gaspardo, Alba <1991&gt. "Canine chronic inflammatory enteropathies: diagnostic markers, endoscopic tecniques and novel therapeutic approaches." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amsdottorato.unibo.it/9696/1/Gaspardo_Alba_-_Tesi_dottorato_XXXIII_ciclo.pdf.

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Canine chronic inflammatory enteropathies (CIE) are a group of diseases characterized by chronic gastrointestinal (GI) symptoms. Once other causes for GI symptoms have been ruled out, subdivision of CIEs occurs through therapeutic response which involves a unique trial. The therapeutic steps include a dietary change, subsequently the introduction of antibiotic therapy (this step has recently been discouraged), the execution of an endoscopy of the digestive tract and the introduction of an immunosuppressive therapy. Understanding the pathogenesis and the type of CIE in is fundamental for a corr

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Gaigneaux, Anthoula. "Determination of diagnostic and prognostic markers in varied tumoral pathologies by ATR-FTIR spectroscopy." Doctoral thesis, Universite Libre de Bruxelles, 2004. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/211150.

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17

Huggett, M. T. "The use of novel diagnostic cell cycle markers and targeted treatment of pancreaticobiliary cancers." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1433745/.

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Adenocarcinoma of the pancreas is one of the top ten leading causes of cancer deaths. In the UK approximately 8000 people are diagnosed with the disease each year. Surgical resection is the only chance of cure and is only possible in a minority of patients. Even after resection, median survival is only 10–20 months and no more than 5–20% of resected patients survive five years. Earlier diagnostic assays and novel treatments are urgently required to improve outcomes. Chapter 1 summarises clinical aspects of pancreatic cancer and current diagnostic and prognostic tests. Chapter 2 gives an introd

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18

Duong, Veasna. "Dengue in Cambodia : epidemiology, molecular evolution, clinical presentation, laboratory diagnostic and markers of severity." Thesis, Montpellier 2, 2011. http://www.theses.fr/2011MON20231/document.

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La dengue, maladie transmise par des moustiques, est causée par l'un des 4 sérotypes du virus de la dengue (DENV). Le Cambodge est un pays d'hyperendémicité de la dengue où les 4 sérotypes en co-circulent. Le programme national de lutte contre la dengue a été établi en 2000 et a fourni des données nécessaires dans la compréhension du profil épidémiologique et de l'évolution du DENV. La dynamique d'évolution virale est caractérisée par des événements de disparition et d'émergence de lignées au sein de chaque sérotype en fonction du temps. La dengue se présente sous différentes formes cliniques

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19

Sahli, David. "Early arterial disease of the lower extremities in diabetes diagnostic evaluation and risk markers /." Doctoral thesis, Umeå : Umeå university, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-26711.

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Ortner, Margarete. "Morpho-functional markers in X-ray computed tomography for respiratory diseases." Paris 5, 2011. http://www.theses.fr/2011PA05S007.

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Ce travail vise à développer un système de diagnostic assisté par ordinateur ciblant les maladies pulmonaires responsables de changements biologiques et morphologiques dans les voies respiratoires. L'intérêt clinique est la compréhension des mécanismes et relations entre la physiologie et le phénotype / génotype du patient. Ce système DAO adopte le concept "image comme marqueur" et explore les données MDCT obtenues en routine clinique. Ainsi, des approches d’investigation basées sur l'image sont abordées pour identifier les marqueurs pathologiques en jeu. L’enjeu majeur est la segmentation vol

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21

Cadd, Verity Anne. "The study of molecular markers for the progression of Barrett's oesophagus to adenocarcinoma to identify markers that can be used as diagnostic tools." Thesis, Cranfield University, 2002. http://dspace.lib.cranfield.ac.uk/handle/1826/3689.

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Barrett's oesophagus is a complication of gastro-oesophageal reflux disease and is the single most important predisposing factor for the development of adenocarcinoma of the oesophagus. New molecular markers are needed for early diagnosis and to monitor disease progression. Telomerase is a ribonuclear protein with reverse transcriptase activity, which uses its own RNA component as a template for the addition of telomeric repeats to the end of chromosomes. Telomerase activity has been studied during the neoplastic progression of Barrett's oesophagus using a TRAP based ELISA technique, which fou

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22

Roupaka, Sofia. "Functional genomics approach to identifying peripheral markers for sheep scrapie." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/33306.

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Scrapie is a transmissible spongiform encephalopathy (TSE) of sheep and goats, for which there is currently no ante-mortem diagnostic test. A rapid, ante-mortem diagnostic test for scrapie would also potentially be important for other TSEs such as bovine spongiform encephalopathy (BSE) and variant Creutzfeldt Jakob's disease (vCJD). The hypothesis of this study was that there is differential gene expression in the blood and peripheral tissues of scrapie infected animals, and that a panel of differentially expressed genes could be identified and used as surrogate markers of infection. An expres

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Kojima, Kyoko. "Mouse modeling of pancreatic ductal adenocarcinoma (PDAC) search for early diagnostic markers and therapeutic targets /." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2009. https://www.mhsl.uab.edu/dt/2009p/kojima.pdf.

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24

Braund, Taylor Austin. "DIAGNOSTIC AND TREATMENT PREDICTIVE MARKERS OF ANXIETY IN MAJOR DEPRESSIVE DISORDER: AN INTEGRATIVE NEUROSCIENCE APPROACH." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/23741.

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Major depressive disorder (MDD) commonly co-occurs with one or more anxiety disorders or with clinically significant levels of anxiety symptoms. Although evidence suggests that anxious forms of depression are predictive of poorer antidepressant treatment outcomes, there is no clear definition of anxious depression, and inferences about associated clinical characteristics are thus limited. The central aim of this thesis was to establish whether comorbid anxiety in people with MDD is clinically useful for identifying diagnostic or treatment predictive markers. To address this aim, several sub ai

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25

Bembich, Sara. "Identification of new diagnostic markers of multiple sclerosis using ORF-selected cDNA phage display libraries." Doctoral thesis, Università degli studi di Trieste, 2009. http://hdl.handle.net/10077/3068.

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2007/2008<br>Multiple sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system (CNS) which typical feature is the plaques of demyelination. The factor triggering the disease is still unknown, but the most diffuse opinion is that the autoimmune reaction is due to a new contact with environmental factors, like virus, that mimic self molecules (molecular mimicry). MS is a T- cell mediated disease. These cells activated by myelin antigens activate, in turn, B lymphocytes, macrophages and cytotoxic lymphocytes which strongly damage oligodendrocytes and neurons, both direct

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26

Honing, Jennifer. "Evaluation and implementation of DNA-based diagnostic methodology to distinguish wheat genotypes." Thesis, Link to the online version, 2007. http://hdl.handle.net/10019/638.

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Nicol, Lisa Margaret. "Diagnostic and prognostic value of current phenotyping methods and novel molecular markers in idiopathic pulmonary fibrosis." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33098.

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Background Idiopathic pulmonary fibrosis (IPF) is a devastating form of chronic lung injury of unknown aetiology characterised by progressive lung scarring. A diagnosis of definite IPF requires High Resolution Computed Tomography (HRCT) appearances indicative of usual interstitial pneumonia (UIP), or in patients with 'possible UIP' CT appearances, histological confirmation of UIP. However the proportion of such patients that undergo SLB varies, perhaps due to a perception of risk of biopsy and additive diagnostic value of biopsy in individual patients. We hypothesised that an underlying UIP pa

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RUGGERONE, BEATRICE. "OXIDATIVE-ANTIOXIDATIVE COMPOUNDS AND LIPID PARAMETERS AS POTENTIAL DIAGNOSTIC AND PROGNOSTIC MARKERS IN ANIMALS WITH SIRS." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/619500.

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Nowadays in veterinary medicine the discrimination between an inflammatory status and a systemic inflammatory response syndrome (SIRS) sometimes related to an infectious disease and with a poorer prognosis, could be difficult, both for the clinicians and the clinical pathologists. An early diagnosis would permit to avoid unnecessary use of antibiotics (mainly to contain the problem of antibiotic resistance) and to establish an appropriate monitoring plan. The aim of the two first described works was to validate in horses the Paraoxonase-1 (PON-1), a negative acute phase protein already used i

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Biesecker, Ronna Lee. "Clinical nutrition expert status as related to selected demographic, diagnostic thinking, knowledge and motivational variables." Diss., The University of Arizona, 1999. http://hdl.handle.net/10150/565584.

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30

Kachroo, Naveen. "Identification of treatment-specific predictive biomarkers in prostate cancer by transcriptional profiling of archival diagnostic biopsies." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707979.

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31

Stead, Thomas. "An investigation into the application of design processes to novel self-use molecular diagnostic devices for sexually transmitted infections." Thesis, Brunel University, 2017. http://bura.brunel.ac.uk/handle/2438/15197.

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The purpose of this research was to investigate the application of design processes to the development of novel self-use molecular diagnostic devices for sexually transmitted infections. The argument proposed in this thesis is that the application of design methods at the earliest research stages into miniaturised, low cost, molecular diagnostic technologies will accelerate and improve the process of translating proof of concept diagnostic technologies into usable devices. Concept development requirements and potential issues and barriers to development were identified through interviews with

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Ambrose, Jason H. "Evaluation of a microsphere-based immunoassay (MIA) in measuring diagnostic and prognostic markers of dengue virus infection." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6995.

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Infections with dengue viruses (DENV) constitute both a global problem as well as locally in Florida. DENV comprise four distinct serotypes of single-stranded RNA viruses and belong to the family Flaviviridae. DENV are among the most medically important arboviruses in the world and cases may currently exceed 400 million per annum. Additionally, dengue established its first recorded endemic transmission cycle in the state of Florida in over a half century, first within the Florida Keys during 2009-10 followed by an unrelated outbreak in Martin County in 2013. The cli

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Ambrosio, Gabriella [Verfasser]. "Ecdysterone Use and Misuse in Sports: Diagnostic Markers in Human Specimen and Determination in Supplements / Gabriella Ambrosio." Berlin : Freie Universität Berlin, 2020. http://d-nb.info/1214241166/34.

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Nagala, Sidhartha. "Correlating thyroid tumour pathology with magnetic resonance biomarkers to improve pre-operative diagnosis." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708232.

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Altadill, Vallespí Tatiana. "Metabolomic study for the identification of diagnostic markers and the characterization of the dissemination process of endometrial cancer." Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/462056.

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El càncer d'endometri (CE) és la malaltia ginecològica més habitual dels països desenvolupats i la quarta causa de càncer en dones. Presenta una incidència que es troba en continu creixement en pacients joves. Donada aquesta problemàtica, en les darreres dècades diverses línies de recerca s'han focalitzat en entendre quins són els canvis moleculars i metabòlics associats al CE. El seu diagnòstic recau en l'avaluació d'una biòpsia endometrial, mètode considerat mínimament invasiu. A més a més, el maneig dels pacients es basa en l'avaluació de les característiques clínico-patològiques del tumor;

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Söderlin, Maria. "A population-based study on early arthritis in southern Sweden : incidence, preceding infections, diagnostic markers and economic burden /." Linköping : Univ, 2003. http://www.ep.liu.se/diss/med/08/24/index.html.

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Söderlin, Maria. "A population-based study on early arthritis in southern Sweden : Incidence, preceding infections, diagnostic markers and economic burden." Doctoral thesis, Linköpings universitet, Reumatologi, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-5225.

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The total annual incidence of arthritis in this prospective cross-sectional study on adults was 115/100 000. The annual incidence of rheumatoid arthritis (RA) was 24/100 000, 29/100 000 for women, and 18/100 000 for men. For reactive arthritis (ReA) the annual incidence was slightly higher, 28/100 000, and for undifferentiated arthritis 41/100 000. The annual incidence of Lyme disease and sarcoid arthritis was low. The annual incidence of arthritis in this study compares well with findings in earlier reports from both registers and case review studies. Almost 50% of the patients in the series

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Alessandria, Maria <1979&gt. "Sleep motor activity in parkinsonian syndromes at onset: a prospective study to determine potential diagnostic and prognostic markers." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amsdottorato.unibo.it/6657/1/ALESSANDRIA_TESI.pdf.

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Aim of this study is to describe the possible diagnostic value of sleep disturbances in the differential diagnosis of neurodegenerative diseases characterized by parkinsonism at onset. 42 consecutive patients with parkinsonian features and disease duration up to 3 years were included in the BO-ProPark study. Each patient was evaluated twice, at baseline (T0) and 16 months later (T1). Patients were diagnosed as Parkinson disease (PD, 27 patients), PD plus (PD with cognitive impairment/dementia or dysautonomia, 4 patients) and parkinsonian syndrome (PS, 11 patients). All patients underwent a ful

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Alessandria, Maria <1979&gt. "Sleep motor activity in parkinsonian syndromes at onset: a prospective study to determine potential diagnostic and prognostic markers." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amsdottorato.unibo.it/6657/.

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Aim of this study is to describe the possible diagnostic value of sleep disturbances in the differential diagnosis of neurodegenerative diseases characterized by parkinsonism at onset. 42 consecutive patients with parkinsonian features and disease duration up to 3 years were included in the BO-ProPark study. Each patient was evaluated twice, at baseline (T0) and 16 months later (T1). Patients were diagnosed as Parkinson disease (PD, 27 patients), PD plus (PD with cognitive impairment/dementia or dysautonomia, 4 patients) and parkinsonian syndrome (PS, 11 patients). All patients underwent a ful

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FIGORILLI, MICHELA. "Polysomnographic markers of REM sleep behavior disorder in Parkinson’s Disease: methodological issues, diagnostic accuracy and progression over time." Doctoral thesis, Università degli Studi di Cagliari, 2019. http://hdl.handle.net/11584/260589.

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Up to 60% of Parkinson’s disease (PD) patients have REM sleep behavior disorder (RBD), a parasomnia characterized by a loss of REM sleep muscle atonia and dream-enacting behaviors, usually associated to vivid dreams. REM sleep without atonia (RSWA), characterized by a sustained tonic and/or phasic muscle activity during REM sleep, is the polysomnographic hallmark of RBD. PD patients with RBD (PDRBD+) are more severely impaired in both motor and non-motor domains, compared to those without RBD, and they have an increased risk of dementia. Thus, RBD may be a biomarker of more widespread/malignan

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Luan, Hemi. "Mass spectrometry based metabolomics for biomarkers of Parkinson's disease." HKBU Institutional Repository, 2017. https://repository.hkbu.edu.hk/etd_oa/396.

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Increasing evidence has shown that abnormal metabolic phenotypes in body fluids reflect the pathogenesis and pathophysiology of Parkinson's disease (PD). However, the relationship between metabolic phenotypes and PD is not fully understood. Mass spectrometry (MS) based metabolomics is a powerful technique, which was frequently used for the sensitive and reproducible detection of hundreds to thousands of metabolites in biofluid samples.. Here we developed and performed MS-based metabolomics studies involving hundreds of human urine samples with data acquired from multiple analytical batches for

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Rautiola, Davin. "Detection of Homocysteine with Bridged Viologen Chemical Probes." PDXScholar, 2014. https://pdxscholar.library.pdx.edu/open_access_etds/1541.

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Increased blood plasma concentrations of the aminothiol homocysteine (Hcy) are associated with a variety of disease states including those which cause impaired renal function, many forms of cardiovascular disease, and neurodegenerative diseases such as Alzheimer's. Therefore, Hcy has the potential to be a significant diagnostic biomarker. Routine monitoring of Hcy plasma concentration is encumbered by the time and resources required to quantify Hcy using currently accepted instrumental analysis methods. As part of the continuing effort to develop a quick, reliable, inexpensive, and user-friend

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Zeng, Qing-Yin. "Development of molecular techniques for fungal diagnostic research." Doctoral thesis, Umeå : Umeå universitet : Arbetslivsinstitutet, 2005. http://kb.se/resolve?urn=urn:nbn:se:umu:diva-656.

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Wakerley, Eleanor. "The use of squiggling : a play technique as a diagnostic aid in the assessment of secondary school-age children with Asperger syndrome." Thesis, University of Hertfordshire, 2009. http://hdl.handle.net/2299/2930.

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Winnicott’s (1968, 1993) play technique squiggling was piloted as a measure of creative thinking abilities and a potential diagnostic aid in the assessment of Asperger syndrome. The internal consistency and inter-rater reliability of squiggling was found to be acceptable. Mixed results were found between the six subscales in terms of concurrent validity with the Torrance Tests of Creative Thinking (TTCT: Torrance, Bal & Safter, 2008). Squiggling subscales Elaboration and Imagination showed signs of psychometric strength. However, Fluency and Originality require revision. Concurrent validity of

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Liefferinckx, Claire. "Evaluation of disease severity in inflammatory bowel diseases: From predictive diagnostic gene markers to treatment optimization based on pharmacokinetics." Doctoral thesis, Universite Libre de Bruxelles, 2019. https://dipot.ulb.ac.be/dspace/bitstream/2013/286479/3/table.docx.

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Inflammatory bowel diseases (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are chronic inflammatory immune-mediated diseases of the gastrointestinal tract. Two-thirds of IBD patients will develop severe disease, with complications that will require frequent surgeries and hospital admissions, and will seriously impair their quality of life. The ultimate clinical challenge of precision medicine in IBD is to find predictive markers to anticipate the development of severe disease and to monitor treatment in these patients.In the first part of my PhD thesis, we have carried out

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Hakuna, Lovemore. "Selective Indicators for Optical Determination of Disease Biomarkers." PDXScholar, 2014. http://pdxscholar.library.pdx.edu/open_access_etds/2053.

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The most abundant biological thiols, homocysteine (Hcy), cysteine (Cys) and glutathione (GSH) have been the subject of intense research due to their association with a wide range of diseases. They play a key role in maintaining the redox status of biological systems. Selective detection methods for these thiols are challenging due to their similar structures and properties. Current commercially available detection methods use separations, fragile and expensive enzymatic or immunogenic materials and complex instrumentation. This has led to a global effort towards developing simple and inexpensi

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Andries, Anne-Claire. "Diagnostic de la dengue : trois solutions pour améliorer la prise en charge des patients et faciliter les études épidémiologiques." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS146/document.

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La dengue est une maladie virale des régions tropicales et subtropicales, transmise par les moustiques du genre Aedes. Le virus de la dengue (DENV) appartient à la famille des Flaviviridae, genre Flavivirus. Si la plupart des infections sont asymptomatiques ou se traduisent par un syndrome fébrile sans gravité, le virus peut aussi causer une maladie plus sévère caractérisée par une fuite plasmatique, avec ou sans hémorragie. Sans prise en charge adéquate, les formes les plus sévères peuvent évoluer vers un syndrome de choc, potentiellement mortel. Il n’existe pas de traitement spécifique de la

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Arrambide, García Georgina. "Study of diagnostic and prognostic clinical, biological, and magnetic resonance imaging markers at the time of a clinically isolated syndrome." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/384610.

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En este trabajo estudiamos marcadores con valor diagnóstico o pronóstico en el momento de presentar un síndrome clínico aislado (CIS, del inglés clinically isolated syndrome). Dado que presentar un CIS representa un riesgo para desarrollar esclerosis múltiple (EM), se considera crucial identificar qué pacientes tendrán un segundo brote y determinar el grado de acumulación de discapacidad a medio y largo plazo. Por ello, aún se considera necesario identificar marcadores que representen los diferentes aspectos de esta enfermedad, especialmente si se demuestra su utilidad en la práctica clínica d

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Sikes, Tiffany Rochelle. "Validation of Loci Conferring Adult Plant Resistance to Powdery Mildew in Wheat Cultivar Massey and Identification of Diagnostic Molecular Markers." Thesis, Virginia Tech, 2014. http://hdl.handle.net/10919/64152.

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Powdery mildew, caused by the pathogen Blumeria graminis (DC) Speer (Syn. Erysiphe graminis DC) f. sp. tritici, is a major disease of wheat (Triticum aestivum L.). Race-specific resistance is easily identified in the field due to its qualitative phenotype and it is easy to incorporate because it is inherited as a single gene. Unfortunately, this type of resistance is easily overcome by the pathogen. Traits associated with quantitative trait loci (QTL) such as adult-plant resistance (APR), have become popular with plant breeders because of their durability over a wide geographic range and ti

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Plonka, Alexandra. "Diagnostic précoce et différentiel des Aphasies Primaires Progressives : apport d'analyses motrices et langagières." Electronic Thesis or Diss., Université Côte d'Azur, 2023. http://www.theses.fr/2023COAZ6015.

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L'Aphasie Primaire Progressive (APP) est un syndrome neurodégénératif caractérisé initialement par un trouble isolé du langage et dont le diagnostic est principalement clinique. Trois formes principales d'APPs sont décrites dans la littérature : l'APP logopénique (APPl), l'APP sémantique (APPvs) et l'APP non fluente/agrammatique (APPnf). Les dernières données de la littérature ont mis en évidence un diagnostic tardif, parfois erroné, associé à la nécessité d'une prise en charge précoce. La création de nouveaux outils pour le diagnostic et la classification des APPs semblent à ce jour indispens

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