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Dissertations / Theses on the topic 'Mass-mapping'

Author: Grafiati

Published: 8 June 2024

Last updated: 31 July 2025

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1

Matsumiya, Nozomi. "Optimization of disulfide mapping using mass spectrometry." Thesis, Kansas State University, 2009. http://hdl.handle.net/2097/1358.

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Master of Science<br>Biochemistry<br>John Tomich<br>One of the important keys to characterize the biological function of a protein is the study of post-translational modification (PTM). Formation of disulfide bond linkages between cysteine residues within a protein is a common PTM which not only contributes to folding and stabilizing the protein structure, but also to accomplishing its native function. Therefore, the study and discovery of structural-functional relationships of expressed proteins using an isolated proteomics approach has been one of the biggest advances within the field of s

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2

Wetzel, Collin. "Global Identification and Mass Mapping of tRNA Isoacceptors Using Targeted Tandem Mass Spectrometry." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1448037316.

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3

Comins, Megan. "Systematic errors in black hole mass measurement using reverberation mapping." Connect to resource, 2008. http://hdl.handle.net/1811/32152.

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4

Flett, Fiona Jane. "Mapping protein-DNA interactions using UV cross-linking and mass spectrometry." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/17996.

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Protein-nucleic acid interactions play essential roles in all living cells in various cellular functions. The study of these interactions can reveal important structural and functional information. UV cross-linking of nucleic acids to proteins in combination with mass spectrometry is a powerful technique to identify proteins, peptides and the amino acids involved in intermolecular interactions within nucleic acid-protein complexes. However, the mass spectrometric identification of cross-linked nucleic acid-protein heteroconjugates in complex mixtures and MS/MS characterisation of the specific

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5

Cao, Xiaoyu. "Mass Exclusion list for RNA modification mapping using LC-MS/MS." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1495807992024166.

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6

Gatti, Marco. "Weak lensing in DES Y3: redshift distributions, shape catalogue, and mass mapping." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/670527.

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En aquesta tesi hem tractat alguns aspectes clau de les lents dèbils gravitacionals en el context d’enquestes fotomètriques. En particular, es van utilitzar simulacions i dades preses durant els primers tres anys d’observacions de l’enquesta de l’energia fosca (DES Y3). Les programacions de DES estan publicades a finals d’aquest any amb les principals anàlisis cosmològiques de DES Y3 i aquesta tesi abasta algunes de les anàlisis. A la part II d’aquesta tesi, ens hem centrat en la tècnica de “clustering-redshift” i el seu part en la principal estratègia de calibració de redshift DES Y3. Cluster

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7

Beasley, Emma. "Detection and mapping of cannabis use in hair samples using mass spectrometry." Thesis, Sheffield Hallam University, 2018. http://shura.shu.ac.uk/24067/.

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Hair differs from other human materials used for toxicological analysis, such as blood or urine, because of its substantially longer window of detection (months to years) enabling retrospective investigations of drug consumption. Due to its solid and durable nature, hair may be analysed centuries after growth with little degradation. Other advantages of hair analysis include the non-invasiveness of its collection, which is of particular importance in infant/child investigations and the ease of sample storage. Although hair analysis offers the potential to reveal information which is not possib

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8

Antony, Alfred Vinod. "A New Tool for Rock Mass Discontinuity Mapping from Digital Images: VTtrace." Thesis, Virginia Tech, 2005. http://hdl.handle.net/10919/32075.

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Manual fracture mapping in tunnels, caverns, mines or other underground spaces is a time intensive and sometimes dangerous process. A system that can automate this task could minimize human exposure to rockfalls, rockbursts or instabilities and facilitate the use of new methods of data visualization such as virtual environments. This research was undertaken to develop VTtrace; a semi-automatic fracture mapping algorithm based on image processing and analysis techniques. Images of a rock exposure surface are made using a â prosumerâ grade digital camera. The grayscale images are preprocesse

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9

Quanico, Jusal. "Development of On-Tissue Mass Spectrometric Strategies for Protein Identification, Quantification and Mapping." Thèse, Université de Sherbrooke, 2014. http://hdl.handle.net/11143/5867.

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Résumé : L’imagerie par spectrométrie de masse est une technique sans marquage permettant la détection et la localisation de protéines à partir de coupes de tissus. Afin de répondre à des problématiques biologiques, le nombre de protéines identifiées doit être amélioré. Une stratégie consiste à réaliser une micro-jonction liquide sur des régions particulières des coupes de tissus afin d’extraire les peptides issus de la digestion in situ des protéines. Plus de 1500 protéines ont identifié sur une zone de 650µm, correspondant à environ 1900 cellules. Une corrélation entre ces données avec cell

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10

Young, Reuben Sam Erskine. "Mapping changes to lipid metabolism within cancer using next-generation mass spectrometry technologies." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/225933/1/Reuben_Young_Thesis.pdf.

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This thesis developed new methods to probe the molecular structure of lipids (fats) that are key components of cellular membranes. Applications of these technologies led to the discovery of previously undescribed lipids and allowed the mapping of their formation and fate in cancer cells and tissues. These fundamental insights into cancer metabolism suggest new targets for the detection and treatment of cancer.

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11

Pendarvis, Ken, Matthew Padula, Jessica Tacchi, et al. "Proteogenomic mapping of Mycoplasma hyopneumoniae virulent strain 232." BioMed Central, 2014. http://hdl.handle.net/10150/610026.

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BACKGROUND:Mycoplasma hyopneumoniae causes respiratory disease in swine and contributes to the porcine respiratory disease complex, a major disease problem in the swine industry. The M. hyopneumoniae strain 232 genome is one of the smallest and best annotated microbial genomes, containing only 728 annotated genes and 691 known proteins. Standard protein databases for mass spectrometry only allow for the identification of known and predicted proteins, which if incorrect can limit our understanding of the biological processes at work. Proteogenomic mapping is a methodology which allows the entir

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12

Van, Aken Paula. "Mapping patterns of meaning: reparation for victims of mass violence in intra-state peace agreements." Thesis, Linnéuniversitetet, Institutionen för samhällsstudier (SS), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-38457.

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In the aftermath of armed conflict, peace and justice are no longer perceived as contradictory. Scholars and practitioners alike have increasingly argued that societies emerging from periods of conflict or repression need to address legacies of past mass violence and human rights abuses in order to sustain peace. This is the rationale behind the evolving field of transitional justice. While it is stated that transitional justice also makes headway in contemporary peace agreements, existing literature tends to remain unspecific. Albeit being the most victim-centred among the range of transition

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13

Hubble, Nick. "George Orwell and mass-observation : mapping the politics of everyday life in England 1936-1941." Thesis, University of Sussex, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249107.

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14

MAZUR, FELIPE PIRES DO RIO. "MAPPING OF SUSCEPTIBILITY TO MASS MOVEMENTS THROUGH ENVIRONMENTAL SIGNATURES IN TIJUCA MASSIF, RIO DE JANEIRO." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2013. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=34874@1.

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A cidade do Rio de Janeiro, assim como outras localidades de relevo montanhoso e clima tropical, sofre, seguidamente, com os problemas causados por movimentos de massa em suas encostas. No verão, a cada temporada de chuvas, novos deslizamentos são contabilizados, acarretando diversos problemas de ordem social e ambiental. O Maciço da Tijuca não foge a esta realidade: localizado em área central do município, suas encostas vem sofrendo com antropizações desde a fundação da cidade. Em uma metrópole que não para de crescer, as encostas deste maciço estão sempre sob pressões da especulação imobiliá

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Phinney, Brett Stanley. "The surface conformation of the Sindbis virus spike complex as determined by mass spectrometry based mapping /." Digital version accessible at:, 2000. http://wwwlib.umi.com/cr/utexas/main.

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Irvine, Adam Grant. "Engineering geological characterisation of the Torlesse Composite Terrane in Canterbury, New Zealand with reference to mechanised tunnelling." Thesis, University of Canterbury. Geological Sciences, 2013. http://hdl.handle.net/10092/8372.

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The Torlesse composite terrane is an important geological unit in Canterbury, New Zealand, making up the backbone of the Southern Alps. It consists of a large group of rock that exhibits a range of engineering geological conditions. This study has been undertaken to characterise the range in engineering geological conditions throughout the Torlesse of Canterbury in order to develop a rock mass classification scheme specific to this abundant and complex rock type. The classification is aimed to aid in TBM tunnelling assessment in the Torlesse, which enables sub-division of an area or tunnel ali

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Yu, Ningxi. "Post-transcriptional Modification Characterizing and Mapping of Archaea tRNAs Using Liquid Chromatography with Tandem Mass Spectrometry." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1552379526695035.

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18

Thomson, Laura Irene. "Connections Between the Mass Balance, Ice Dynamics, and Hypsometry of White Glacier, Axel Heiberg Island, Nunavut." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35106.

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This thesis investigates how changing climate conditions have impacted the mass balance, dynamics and associated hypsometry (area-elevation distribution) of White Glacier, an alpine glacier on Axel Heiberg Island, Nunavut. The first article describes the production of a new map of White Glacier from which changes in ice thickness and glacier hypsometry could be determined. A new digital elevation model (DEM) was created using >400 oblique air photos and Structure from Motion, a method built upon photogrammetry but with the advantage of automated image correlation analysis. The result of this

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19

Roberts, Jason L. "Place Perception, Cognitive Maps, and Mass Media: The Interrelationship Between Visual Popular Culture and Regional Mental Mapping." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/33020.

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There can be little dispute that todayâ s society makes extensive use of mass media. Movies, television, and radio are far more prominent today than ten years ago, both locally and globally. We rely on these forms of communication for news and information and entertainment and recreation. New technologies increase our access and our dependence on mass media. In fact, in the U.S. the average person spends 40 percent of their time attending to television at some level (Adams, 1992). Adams then goes on to say that culture and television are clearly involved in reciprocal relations: televisi

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Lobue, Peter. "Towards the Parallel, Accurate, and High-throughput Mapping of RNA Modifications by Liquid Chromatography Tandem Mass Spectrometry." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1595005836099446.

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21

Krupicka, Vaclav. "Development of High Resolution Mass Spectrometry Techniques for Structural Analysis and Molecular Mapping of Cultural Heritage samples." Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0130.

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Ce travail de thèse propose le développement de nouvelles méthodologies en spectrométrie de masse (MS) haute résolution appliquées aux échantillons du Patrimoine Culturel (CH). En particulier, les développements se concentrent sur l’analyse protéomique top-down (TD) et l’imagerie par spectrométrie de masse MALDI (MSI), nous permettant de proposer respectivement des alternatives à l’analyse protéomique bottom-up (BU), et d’obtenir une cartographie précise des composés organiques et inorganiques des échantillons étudiés. Le premier chapitre contextualise la MS dans le domaine du patrimoine cultu

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22

Colley, Richard T. III. "Development of a Machine Vision System for Mass Flow Sensing and High-Resolution Mapping of Granular Fertilizer Application." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1543564969065918.

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23

Domingo, Sabugo María. "Systematic errors in the characterization of rock mass quality for tunnels : a comparative analysis between core and tunnel mapping." Thesis, KTH, Jord- och bergmekanik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-233126.

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This thesis analyzes the potential systematic errorin the characterization of the rock mass quality in borehole and tunnel mapping. The difference when assessing the rock mass quality refers to the fact that the characterization performed on drilled rock cores are commonly done on-meter length, while the tunnel section can be up to 20-25 m wide. At the same time, previous studies indicate that the engineering geologist tends to characterize the rock mass quality during tunnel excavation with a conservative estimation of the parameters defining the rock mass quality to ensure a sufficient rock

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Chen, Sharon S. "Peptide sequence assignments by probabilistic peptide profile matching to an annotated peptide database /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/8084.

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Yilmaz, Cagatay. "Gis-based Landslide Susceptibility Mapping In Devrek (zonguldak &amp." Master's thesis, METU, 2007. http://etd.lib.metu.edu.tr/upload/2/12608805/index.pdf.

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The purpose of this study is to evaluate and to compare the results of bivariate statistical analysis conducted with three different data sets in Geographical Information Systems (GIS) based landslide susceptibility mapping applied to the Devrek region. The data sets are created from the seed cells of crowns and flanks, only crowns, and only flanks of the landslides by using 10 different parameters of the study area. To increase the data dependency of the analysis, all parameter maps are classified into equal frequency classes based directly on the percentile divisions of each seed cells data

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Solivio, Beulah Mae Ann. "Studying the RNA-Recognition Site of RNase U2 for a More Diverse Bioanalytical Toolbox in RNA Modification Mapping." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin156387231304478.

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27

Meehan, Michael Joseph. "Active site mapping of iterative polyketide synthases and the detection of polyketide intermediates using high-resolution Fourier Transform mass spectrometry." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1464918.

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Thesis (M.S.)--University of California, San Diego, 2009.<br>Title from first page of PDF file (viewed July 10, 2009). Available via ProQuest Digital Dissertations. Includes bibliographical references (p. 136-148).

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Zhang, Liwen. "Characterization of histone post-translational modification using reversed-phase high performance liquid chromatography and fourier transform ion cyclotron resonance mass spectrometry." Connect to this title online, 2003. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1054660495.

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Thesis (Ph. D.)--Ohio State University, 2003.<br>Title from first page of PDF file. Document formatted into pages; contains xv, 219 p.; also includes graphics (some col.) Includes bibliographical references (p. 147-173). Available online via OhioLINK's ETD Center

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Sanchez, Washington Hugo. "Cataract affected infant lens tissue and protein specific mapping of intact tissue analysis by MALDI-TOF/MS." Thesis, Queensland University of Technology, 2002.

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PETTERSSON, SANDRA-MARIA, and MADELEINE HILLMAN. "Knit On Demand : en studie i utförandet av konceptet masskundanpassade, stickade modekläder." Thesis, Högskolan i Borås, Institutionen Textilhögskolan, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-20190.

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Textilhögskolan i Borås startade projektet Knit On Demand i syftet att undersöka och utvärdera complete garment teknologin. Idén bygger på konceptet masskundanpassning inom området stickning. Huvudaktörerna i Knit On Demand projektet är Textilhögskolan i Borås, återförsäljaren SOM Concept i Stockholm samt Ivanhoe, tillverkare av stickade kläder. Målet med detta arbete är att identifiera och beskriva alla processteg, från den tidpunkt då kunden kliver in i butiken i Stockholm tills det färdiga plagget leverats. Vårt arbete går även ut på att hitta och beskriva förbättringsmöjligheter samt tillh

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Benhalima, Mehdi. "Evaluation of the differences in characterization and classification of the rock mass quality : A comparison between pre-investigation, engineering geological forecast and tunnel mapping in the Northern Link project and the Cityline project." Thesis, KTH, Jord- och bergmekanik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-195743.

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In the construction of a tunnel, the characterization of the rock mass is performed in three different steps, in the pre-investigations, in the engineering geological forecast and in the tunnel mapping during construction. There has in previous work been observed that discrepancies exist between the results from these different steps, with a tendency to assign poorer rock mass quality in the tunnel mapping than in the pre-investigations and in the engineering geological forecast. One example is the work done by Kjellström [1] on the Cityline where the divergence in rock mass quality was analyz

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Song, Yang. "Protein Primary and Quaternary Structure Elucidation by Mass Spectrometry." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1437649750.

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CANDONI, OLIVIERO. "Evoluzione morfodinamica di fenomeni di insabilità gravitativa nel bacino di Crotone-Spartivento, Sud Italia, attraverso integrazione di dati geofisici e geologici." Doctoral thesis, Università degli Studi di Trieste, 2019. http://hdl.handle.net/11368/2950453.

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I fenomeni di instabilità gravitativi sono noti per essere ampiamente diffusi negli ambienti marini, poiché essi modellando la morfologia del fondale marino, dalle zone della scarpata continentale fino alle piane abissali. Inoltre, i fenomeni di instabilità gravitativi sono una delle fonti principale di un'enorme quantità di sedimenti che dalle piattaforma continentali vengono trasportati fino alle piane abissali. Lo studio di questi processi è importante perché permette di capire le dinamiche che li regolano e perché questi fenomeni possono rappresentare potenziali rischi per le attività uman

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Elmo, Davide. "Evaluation of a hybrid FEM/DEM approach for determination of rock mass strength using a combination of discontinuity mapping and fracture mechanics modelling, with particular emphasis on modelling of jointed pillars." Thesis, University of Exeter, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439831.

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MANTOVANI, Bárbara. "Mapeamento de risco a movimentos de massa e inundação em áreas urbanas do município de Camaragibe." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/17957.

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Submitted by Irene Nascimento (irene.kessia@ufpe.br) on 2016-10-06T19:58:27Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação Bárbara Mantovani.compressed.pdf: 14370352 bytes, checksum: b17fd82ef7c294af0977e1eb132200f3 (MD5)<br>Made available in DSpace on 2016-10-06T19:58:27Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação Bárbara Mantovani.compressed.pdf: 14370352 bytes, checksum: b17fd82ef7c294af0977e1eb132200f3 (MD5) Previous issue date: 2016-07-29<br>capes<br>

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Sanchez, Washington H. "Elucidating the role of silicone in the treatment of burn scars : an essential step in the development of improved treatment products." Queensland University of Technology, 2006. http://eprints.qut.edu.au/16287/.

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Hypertrophic scarring is a common occurrence for severe burn victims leading to major functional, physiological, and aesthetic effects to the patients. Limiting the hypertrophic scarring of the patients alleviates the functional, physiological, and aesthetic effects. Silicone gels, over the past decade, have been widely used to remediate and limit hypertrophic scarring but the mechanism of action is yet to be determined. One explanation has been that hydration of the outermost area of the burn is induced by the silicone gel . However, non-silicone polymers which increase hydration could no

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Sanchez, Washington Hugo. "Elucidating the role of silicone in the treatment of burn scars : an essential step in the development of improved treatment products." Thesis, Queensland University of Technology, 2006. https://eprints.qut.edu.au/16287/1/Washington_Sanchez_Thesis.pdf.

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Hypertrophic scarring is a common occurrence for severe burn victims leading to major functional, physiological, and aesthetic effects to the patients. Limiting the hypertrophic scarring of the patients alleviates the functional, physiological, and aesthetic effects. Silicone gels, over the past decade, have been widely used to remediate and limit hypertrophic scarring but the mechanism of action is yet to be determined. One explanation has been that hydration of the outermost area of the burn is induced by the silicone gel . However, non-silicone polymers which increase hydration coul

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Podsiadło, Iwona Katarzyna. "Methods for the analysis of time series of multispectral remote sensing images and application to climate change variable estimations." Doctoral thesis, Università degli studi di Trento, 2021. http://hdl.handle.net/11572/322351.

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In the last decades, the increasing number of new generation satellite images characterized by a better spectral, spatial and temporal resolution with respect to the past has provided unprecedented source of information for monitoring climate changes.To exploit this wealth of data, powerful and automatic methods to analyze remote sensing images need to be implemented. Accordingly, the objective of this thesis is to develop advanced methods for the analysis of multitemporal multispectral remote sensing images to support climate change applications. The thesis is divided into two main parts an

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Junior, Alberto Ferreira do Amaral. "Mapeamento geotécnico aplicado a análise de processos de movimentos de massa gravitacionais: Costa Verde - RJ - escala 1:10.000." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/18/18132/tde-05042007-151540/.

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Este trabalho apresenta um conjunto de atividades desenvolvidas e os respectivos resultados obtidos no decorrer dos estudos relacionados ao mapeamento geotécnico e movimentos de massa gravitacionais realizados em uma área que compreende 60 \'KM POT.2\', sendo 41 \'KM POT.2\' de encosta e 19 \'KM POT.2\' de planícies, localizada na região da Costa Verde-RJ, contemplando parte dos municípios de Itaguaí e Mangaratiba. O estudo foi realizado em três etapas distintas: definição dos atributos, levantamento de dados e análise dos resultados. Como resultado do mapeamento geotécnico foram elaborados

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Skupien, Kathryn Stephanie. "Colors and Mapping: The Right to Receive Information." Scholar Commons, 2013. http://scholarcommons.usf.edu/etd/4845.

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Color is used in everything we see and do and it often can be used for effect and representation, particularly on maps and transportation signage. This study explores the issues that the color blind population exhibits when viewing these maps and signs. Seeing that 8%#37; of the male population is afflicted with some form of color blindness, it is pertinent that research reflect these issues and take into consideration the Right to Receive Information for this population. A qualitative method using Photovoice and interviews was used to determine whether this population considers itself having

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Remy, Benjamin. "Generative modeling for weak lensing inverse problems." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASP163.

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Le lentillage gravitationnelle, qui génère un effet de déformation des images de galaxies lointaines à travers l'influence de densités de matières massives dans la ligne de visée, est très prometteur pour répondre aux questions relatives à la matière noire et à l'énergie sombre. Cet effet permet de sonder directement la distribution de matière noire dans l'Univers, qui est invisible autrement. Dans le régime où ces déformations sont faibles, il est possible de cartographier la distribution de matières projetées dans la ligne de visée, appelée carte de masse, à partir de la mesure de la déforma

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Maxwell, Susan. "Mapping invisible cities : addressing the complexities of achieving polyphonic archives." Thesis, Northumbria University, 2016. http://nrl.northumbria.ac.uk/36136/.

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In the 1990s and 2000s, the theory on which professional practice of archivists and records managers drew was reviewed, in light of cultural and technological changes and of postmodernist philosophies. In particular, the theoretical narrative of the “neutral archives” was terminally disrupted, and more explicit responsibility attributed to the profession for actively seeking to redress the way that power imbalances in contemporary society were reflected in ‘the archive’. Professional archivists and records managers began to look for ways in which as professionals they could counteract these ar

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Stasiak, Lukasz. "Functional analysis of the fat mass and obesity associated (Fto) gene and protein." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:74abbb87-26f6-423d-b231-2d910f707bcd.

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Genome wide association studies have shown that common variants in the human fat mass and obesity-associated (FTO) gene predispose to obesity and increased fat mass. Mice globally lacking Fto are lean, while mice globally overexpressing Fto have increased body weight due to increased fat mass. FTO protein was shown to localise to the nucleus and demethylate ssDNA and ssRNA. However, the mechanisms by which FTO mediates its effects on body phenotype remain unknown. In this thesis, I found that native FTO can be detected in both the nucleus and the cytoplasm during interphase, and that nuclear F

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Patel, Anjali. "An Integrated Proteomic Approach for Mapping the ALS-linked TDP-43 Interactome." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/42687.

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Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which an RNA-binding protein, TDP-43, mislocalizes and pathologically accumulates from its normal nuclear locale to the cytosol. Given that the subcellular localization and expression of TDP-43 is tightly regulated, we posit that identifying novel interactors of wild-type and mutant TDP-43 could reveal insight into networks involved in regulating its localization, ultimately driving neurodegeneration in ALS. Using CRISPR/Cas9, our lab previously generated knock-in cell lines expressing GFP in the endogenous TARDBP locus (

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Macarthur, Deborah Jane. "Mapping the proteome of Streptococcus gordonii." University of Sydney. Health Science, 2005. http://hdl.handle.net/2123/686.

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Streptococcus gordonii is a primary coloniser of the tooth surface where it efficiently ferments carbohydrates at pH levels above 6.0. By not being able to maintain the pH of dental plaque to a level required for enamel dissolution, the dominance of S. gordonii in dental plaque is considered a sign of a healthy oral cavity. However, upon entering the bloodstream and encountering a rise in pH, S. gordonii may become pathogenic, being one of the major causative organisms associated with infective endocarditis. Proteome analyses of S. gordonii grown at steady state in a chemostat allowed t

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Macarthur, Deborah Jane. "Mapping The Proteome Of Streptococcus Gordonii." Thesis, The University of Sydney, 2005. http://hdl.handle.net/2123/5097.

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Streptococcus gordonii is a primary coloniser of the tooth surface where it efficiently ferments carbohydrates at pH levels above 6.0. By not being able to maintain the pH of dental plaque to a level required for enamel dissolution, the dominance of S. gordonii in dental plaque is considered a sign of a healthy oral cavity. However, upon entering the bloodstream and encountering a rise in pH, S. gordonii may become pathogenic, being one of the major causative organisms associated with infective endocarditis. Proteome analyses of S. gordonii grown at steady state in a chemostat allowed t

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Patil, Ujwal S. "Magnetic nanoparticles containing labeling reagents for cell surface mapping." ScholarWorks@UNO, 2015. http://scholarworks.uno.edu/td/2049.

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Cell surface proteins play an important role in understanding cell-cell communication, cell signaling pathways, cell division and molecular pathogenesis in various diseases. Commonly used biotinylation regents for cell surface mapping have shown some potential drawbacks such as crossing the cell membrane, difficult recovery of biotinylated proteins from streptavidin/avidin beads, interference from endogenous biotin and nonspecific nature of streptavidin. With aim to solve these problems, we introduced sulfo-N-hydroxysuccinimidyl (NHS) ester functionalized magnetic nanoparticles containing clea

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Strauss, Catherine. "Mapping the carnival: conceptions of public safety in conservative prison policy and in the work of prison abolition." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106251.

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In this thesis I examine a punitive moment in Canadian corrections policy and practice that began in 2006 with the Conservative Party's election to office. I consider this moment through its founding policy document, A Roadmap to Strengthening Public Safety. The Roadmap's key punitive arguments are based in its construction of a Changing Offender Profile, a term that draws upon the archetypal colonial constructions of the lawless Native offender and the law-abiding Canadian national. These constructions still inform dominant notions of 'prisoner' and 'public' today. In contrast, the political

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Gutsche, Robert Edward Jr. "Mediated constructions and lived experiences of place: an analysis of news, sourcing, and mapping." Diss., University of Iowa, 2012. https://ir.uiowa.edu/etd/1462.

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This dissertation advances previous research on the journalistic interpretive community by placing news at the center of a community's construction of place. By focusing on the construction of Iowa City, Iowa's "Southeast Side" - neighborhoods home to predominantly newly arrived black residents from Chicago and other urban areas - this study identifies dominant news characterizations of the Southeast Side that mark the place as a "ghetto" or "inner city." Beyond providing information about community issues and social conditions from southeastern neighborhoods, the term Southeast Side performed

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Ghaste, Manoj Shahaji. "Comprehensive mapping of volatile organic compounds in fruits." Doctoral thesis, country:IT, 2015. http://hdl.handle.net/10449/26348.

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Volatile organic compounds (VOCs) are the key aroma producers in fruits and sensory quality of fruits is widely determined by qualitative and quantitative composition of VOCs. The aroma of grape is a complex of hundreds of VOCs belonging to different chemical classes like alcohols, esters, acids, terpenes, aldehydes, furanones, pyrazines, isoprenoids and many more. VOCs play important role as they determine the flavor of grapes and wine made from it. The objective of this thesis is to study of VOCs through development of different mass spectrometry based analytical methodologies and its applic

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