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Dissertations / Theses on the topic 'Mass Spectrometry technique'

Author: Grafiati

Published: 9 March 2023

Last updated: 19 July 2025

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1

Collin, Olivier L. "Development of a Novel Tandem Mass Spectrometry Technique for Forensic and Biological Applications." View abstract, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3292877.

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2

COGHI, MARIA DONATA. "Samdi mass spectrometry for high yield protein modification reaction development." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/50887.

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Efficient chemical strategies that attach synthetic molecules to desired positions on protein surfaces are useful tools in the field of chemical biology and represent one major prerequisite for the development of new drugs and materials. Protein modification with polyethylene glycol (PEG) groups is indeed routinely performed on therapeutic proteins to improve serum half-life, or even cytotoxins or imaging agents are efficiently conjugated to cancer-targeting elements. In a typical approach, a synthetic functional group of interest is attached to a uniquely reactive amino acid group introduced

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3

Sproch, Norman K. "Electrospray mass spectrometry : an investigation of non- covalent interactions of cytochrome c/crown ether complexes and applied methods of computational chemistry." Virtual Press, 1994. http://liblink.bsu.edu/uhtbin/catkey/917033.

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This research is directed at developing the interplay of experimental and computational methods in the area of biochemical mass spectrometry. The experimental method is that of electrospray ionization mass spectrometry (ESI-MS). The computational methods employed are those of semi-empirical quantum mechanics and molecular modeling.The use of Electrospray Mass Spectrometry was developed to investigate whole proteins and the non-covalent complexes that may be formed with small molecules. This method provides the soft ionization needed to accurately determine a noncovalently bound complex's mass

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4

Thiery, Gwendoline. "Imagerie par désorption laser/spectrométrie de masse de multiples marqueurs spécifiques : développement de la technique TAMSIM "Targeted Multiplex Mass Spectrometry Imaging"." Paris 6, 2008. http://www.theses.fr/2008PA066253.

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La protéomique est devenue un domaine de recherche essentiel en biologie et en médecine. Afin, de répondre aux enjeux de cette discipline, il est nécessaire de pouvoir caractériser et localiser les protéines exprimées au niveau cellulaire. De nombreuses techniques d’analyses in situ des ces protéines considérées comme étant des marqueurs spécifiques d’une pathologie existent et sont utilisées en routine, notamment pour le suivi des cancers, dans de nombreux laboratoires d’anatomo pathologie. La plus répandue est l’immunohistochimie (IHC). Cette technique consiste à révéler spécifiquement in si

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5

Spencer, Matthew Todd. "New approaches for the chemical and physical characterization of aerosols using a single particle mass spectrometry based technique." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3264603.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed August 2, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.

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6

Angelico, Vincent James. "The development of a mass spectrometry-based technique that uses low energy ion-surface collisions to characterize surfaces." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/280148.

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Low energy (tens of eV) ion-surface collisions carried out in a tandem mass spectrometer are investigated as a tool to characterize self-assembled monolayer (SAM) films. The target films are prepared by spontaneous chemisorption of thiol-based (HS-R) compounds onto Au (111) substrates. Most of the films used as targets contain alkane or fluoro-alkane backbones, some with unique groups in the terminal position (e.g., -CD₃, -OH, -OC(O)CF₃). Pyrazine is the most frequently used probe ion, however in certain cases other small organic molecules are also used. Common interactions between the impingi

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7

Tang, Jianhua. "Development of a Novel Gradient Chromatofocusing Tandem Mass Spectrometry Technique for the Determination of Cationic Compounds in Biofluids; Identification of Caspase 3 Cleavage Sites of NHE-1 by High Performance Liquid Chromatography-Mass Spectrometry." Cleveland State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=csu1247344073.

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8

Tang, Jianhua. "Development of a novel gradient chromatofocusing tandem mass spectometry technique for the determination of cationic compounds in biofluids identification of caspace 3 cleavage sites of nhe-1 by high performance liquid chromatography- mass spectrometry /." Cleveland, Ohio : Cleveland State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=csu1247344073.

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Thesis (Ph. D.)--Cleveland State University, 2009.<br>Abstract. Title from PDF t.p. (viewed July 29, 2009). Includes bibliographical references (p. 105). Available online via the OhioLINK ETD Center and also available in print.

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9

Fedrizzi, Bruno. "Identification, quantitation and origin of sulfur compounds in grape products. An approach via hyphenated mass spectrometry techniques." Doctoral thesis, Università degli studi di Padova, 2010. http://hdl.handle.net/11577/3426543.

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The contribute of the Analytical Chemistry in the study of complex matrices, as for instance foodstuff, is crucial. In particular the development of chromatographic methods allows to quantify important technological, microbiological and physiological markers. The ensemble of all these information furthers a deeper and higher knowledge. This Ph.D. project was designed to define the tools and evaluate the contribution of an important class of molecule on wine aroma. Grape products are really important in the cultural and dietary Italian traditions; moreover Italy is both the first producer a

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10

Shewmaker, Patricia Lynn Wallace. "Enhanced biodegradation of phenolic compounds and cellular fatty acid analysis of bacteria using infrared pyrolysis/gas chromatography-mass spectrometry." Diss., Georgia Institute of Technology, 1999. http://hdl.handle.net/1853/25732.

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11

Sergeyeva, Viktoriya. "Développement d'une technique innovante de dosimétrie en réacteur pour la caractérisation du spectre neutronique dans le domaine d'énergie 1 keV - 1 MeV." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4069/document.

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La dosimétrie neutronique en réacteur se base sur l'analyse de l'activité de dosimètres irradiés, dont certains isotopes-cibles sont l'objet de réactions d'activation ou de fission sous l'effet des neutrons. Les différentes cibles sont sensibles aux neutrons d’énergie particulière. La caractérisation des spectres neutroniques est bien établie dans les domaines thermique, epithermique (Eneutron <1 keV) et rapide (Eneutron >1 MeV), mais il y a une absence de détecteur dans le domaine énergétique entre 1 keV et 1 MeV. Le travail de thèse a abouti sur un choix final: la capture (n, γ) s

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12

Wang, Tongwen. "Hyphenated HPLC-MS technique for analysis of compositional monosaccharides of transgenic corn glycoprotein and characterization of degradation products of diazinon, fonofos and aldicarb in various oxidation systems." Diss., Rolla, Mo. : University of Missouri-Rolla, 2007. http://scholarsmine.mst.edu/thesis/pdf/WangTongwen_09007dcc804e975c.pdf.

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Thesis (Ph. D.)--University of Missouri--Rolla, 2007.<br>Vita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed April 23, 2008) Includes bibliographical references.

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13

Reid, Joy Emily. "The development and geological application of a whole rock-LA-ICP-MS technique for the determination of high field strength elements." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0004/MQ42434.pdf.

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14

Wirtz, Tom. "Optimisation de l'analyse quantitative des matériaux en utilisant des agrégats MCs[indice]x[exposant]+ : application au développement de la technique Cation Mass Spectrometry (CMS)." Vandoeuvre-les-Nancy, INPL, 2002. http://www.theses.fr/2002INPL073N.

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La spectrométrie de masse d'ions secondaires (SIMS), technique extrêmement sensible pour l'analyse de surfaces, souffre de sérieux problèmes de quantificàtion causés par la forte variation de la probabilité d'ionisation des ions secondaires avec la composition de l'échantillon (" effet de matrice "). Pour y remédier, on a souvent recours à la technique MCs[indice]x[exposant]+ consistant à incorporer du Cs dans le matériau et à détecter les espèces intéressantes sous forme de clusters. Dans ce travail, nous avons tenté d'optimiser cette technique analytique avantageuse. Dans un premier temps, n

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15

Torabi-Pour, Nosrollah. "Use of immunobead-purification technique in combination with high performance liquid chromatography and mass spectrometry for isolation and identification of HLA class1 antigen bound peptides." Thesis, Queen Mary, University of London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246922.

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16

Homazava, Nadzeya. "Development of a novel microflow-capillary technique online hyphenated to the inductively coupled plasma mass spectrometry for the spatial- and time-resolved investigation of local corrosion /." [S.l.] : [s.n.], 2009. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000288126.

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17

Trefjord, Terese. "Investigations on the Applicability of Membrane Introduction as a Sampling Technique for Oil in Air and Water with Flame Ionization Detector (FID) and Mass Spectrometry (MS) Detection." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for kjemi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-16363.

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During a membrane introduction (MI) analysis the analytes are separated from the bulk matrix (e.g. air or water) by a semi-permeable membrane and transported to the detector by a carrier gas (usually helium). The most commonly used detector for MI-analyses is the mass spectrometer, resulting in membrane introduction mass spectrometry (MIMS). The main advantages of MIMS are short response times, high sensitivity, simplicity and elimination of sample preparation and pre-separation. Membrane introduction analyses are suitable for detection of volatile organic compounds (VOCs) and semi volatile or

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18

Stoytschew, Valentin [Verfasser], Birgit [Akademischer Betreuer] Kanngießer, Birgit [Gutachter] Kanngießer, and Milko [Gutachter] Jakšić. "Megaelectron volt secondary-ion mass spectrometry – yield dependence on experimental parameters and new capabilities of the technique / Valentin Stoytschew ; Gutachter: Birgit Kanngießer, Milko Jakšić ; Betreuer: Birgit Kanngießer." Berlin : Technische Universität Berlin, 2019. http://d-nb.info/1187333298/34.

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19

Diegor, Wilfredo G. "Development of a high pressure digestion technique and a data acquisition/reduction procedure and their application to the ICP-MS analysis of urban sediments and soils from Cebu, Philippines." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0003/MQ42368.pdf.

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20

Fox, ramos Alexander. "Exploration de la diversité chimique des Apocynaceae par la technique des réseaux moléculaires : de la création d’une base de données vers l’annotation in silico." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS543/document.

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Les alcaloïdes indolo-monoterpéniques (AIMs) constituent une classe de molécules naturelles très étudiée en raison d’un fort potentiel pharmacologique et thérapeutique et d’une grande diversité structurale. D’autre part, les techniques de déréplication par chromatographie liquide couplée à la spectrométrie de masse tandem ont évolué récemment, avec l’émergence de l’approche par réseaux moléculaires (molecular networking). Dans ce contexte, nous avons créé une base de données de spectres de masse tandem moyennés de 172 AIMs témoins, en collaboration avec plusieurs équipes de pharmacognosie dans

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21

Jeanne, dit Fouque Dany. "Analyses structurale et quantitative de composés iso-mères/bares en mélange par spectrométrie de masse tandem et multi-étapes." Thesis, Brest, 2018. http://www.theses.fr/2018BRES0116.

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Ces travaux de thèse sont consacrés au développement de nouvelles méthodologies pour l’analyse structurale et quantitative de composés isomères ou isobares en mélange par spectrométrie de masse en tandem (MS/MS) ainsi que par la technique des ions survivants (SY). À l’aide de cette technique, nous avons développé une méthode de « purification collisionnelle en phase gaz » consistant à purifier un composé par fragmentation sélective du contaminant isomère ou isobare afin de permettre l’analyse structurale et quantitative du composé d’intérêt. Nous avons montré que cette approche peut être utili

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22

LAZZATI, ZELDA. "Speciation of particulate matter's organic fraction and its mechanis of action on human health." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2009. http://hdl.handle.net/10281/7466.

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Three main researches have been employed for the implementation of a protocol analysis for the characterization and quantification of the lignin fraction in the particulate matter at the concentration matrix level; the implementation of different methods of analysis of the toxic interesting pollutants, Oxy-PAHs; Nitro-PAHs and the Bisphenol A, that together with the large set of performed analysis, allowed the characterization of some PM fractions in relation with Indoor and Outdoor concentrations, human exposure and Urban – Rural – Remote sites composition. At last an in silica method was dev

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23

Sakata, Shuhei. "Development of analytical technique for precise age determination of Quaternary zircons with the correction of the initial disequilibrium on U-Th-Pb decay series using a laser ablation-ICP-mass spectrometry." 京都大学 (Kyoto University), 2015. http://hdl.handle.net/2433/199112.

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24

Lorenzetti, Raquel. "Metodo de quantificação de nucleotideos por HPLC-MS/MS e avaliação da atividade de analogos de sildenafil sobre fosfodiesterase." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309493.

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Orientador: Gilberto de Nucci<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-10T06:11:56Z (GMT). No. of bitstreams: 1 Lorenzetti_Raquel_D.pdf: 2089930 bytes, checksum: f6ed8b98e678ffdfc6051c645efc8b4b (MD5) Previous issue date: 2007<br>Resumo: No presente trabalho foi padronizado um novo método para a dosagem da atividade de fosfodiesterase in vitro, por HPLC-MS/MS. Este novo método conseguiu apresentar exatidão, precisão, sensibilidade e rapidez nas análises; monitorando os nucleotídeos (AMP, GMP, AMPc e GMPc). O

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25

Stubberud, Karin. "Studies of Micellar Electrokinetic Chromatography as an Analytical Technique in Pharmaceutical Analysis - an Industrial Perspective." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5281-7/.

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26

Bouvier, Caroline. "Étude du vieillissement de peintures anciennes par imagerie par spectrométrie de masse 3D." Electronic Thesis or Diss., Sorbonne université, 2022. http://www.theses.fr/2022SORUS008.

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L'objectif de la thèse était d'évaluer le potentiel de l'imagerie TOF-SIMS, notamment 3D, pour étudier la composition chimique de façon fiable sur des coupes stratigraphiques de peintures anciennes. L’imagerie TOF-SIMS peut cartographier simultanément les matières organiques et inorganiques à l’échelle micrométrique, répondant à des questions sur les tableaux anciens, comme l’élucidation de la nature des liants et pigments des différentes couches, ou l’étude des transformations chimiques des ingrédients par l’action du temps et des interactions. La construction d'une base de donnée de spectres

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27

Mitchell-Roberts, Alisha C. "Advanced techniques in mass spectrometry for forensic applications." [Gainesville, Fla.] : University of Florida, 2005. http://purl.fcla.edu/fcla/etd/UFE0012146.

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28

Müller, Lukas Niklaus. "Novel computational techniques for quantitative mass spectrometry based proteomics /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17802.

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29

Wooding, Madelien. "Identification of micropollutants by combined chromatography and mass spectrometry techniques." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/63364.

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The presence of micropollutants in South African aquatic systems has emerged as an issue of public health concern. Micropollutants, such as endocrine disrupting chemicals (EDCs) and antiretroviral compounds, have previously been detected in surface water of South Africa. Micropollutants are often present in complex environmental matrices at ultra-trace levels, complicating their detection. In order to address shortcomings with traditional sample preparation methods, an inhouse developed cheap, disposable polydimethylsiloxane (PDMS) sorptive sampler was developed. The validity of the PDM

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30

Kapoore, Rahul Vijay. "Mass spectrometry based hyphenated techniques for microalgal and mammalian metabolomics." Thesis, University of Sheffield, 2014. http://etheses.whiterose.ac.uk/8234/.

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In metabolomics, the analytical challenge is to capture the chemical diversity of the metabolome. With the current technologies only a portion of the metabolome can be analysed. As a result there is a drive to direct significant analytical efforts towards capturing the metabolome or changes in the metabolome reliably and reproducibly in biological systems. Apart from analytical challenges, the challenges also include development of appropriate methodologies to quench and extract metabolites which is a crucial parameter in sample preparation and is required to achieve an accurate representation

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31

Alvarez, David A. "The development of time-of-flight mass spectrometry techniques for studying the surface of Europa for astrobiology." Birmingham, Ala. : University of Alabama at Birmingham, 2009. https://www.mhsl.uab.edu/dt/2009m/alvarez.pdf.

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32

Nielsen, Michael Lund. "Characterization of Polypeptides by Tandem Mass Spectrometry Using Complementary Fragmentation Techniques." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7409.

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33

Ford, Michael James. "Modern mass spectrometric techniques applied to occupational hygiene analysis." Thesis, University of East Anglia, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268553.

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34

Chainet, Fabien. "Spéciation du Silicium dans les charges d'hydrotraitement." Thesis, Pau, 2012. http://www.theses.fr/2012PAUU3022/document.

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Le silicium est connu pour être un poison sévère des catalyseurs d'hydrotraitement (HDT). L’objectif de la thèse a donc été de mettre en place des outils analytiques pour la spéciation du silicium afin d'identifier toutes les molécules silicées réellement formées dans les charges d'HDT. Différents outils analytiques de pointe basés sur des couplages entre la chromatographie en phase gazeuse et la spectrométrie de masse (MS et ICP/MS) ont été développés. Étant donnée la réactivité de certaines espèces silicées, des échantillons représentatifs de la dégradation du PDMS ont été produits dans des

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35

Goolsby, Brian James. "Techniques for improved mass spectrometric analysis of biologically relevant molecules produced by MALDI and ESI in the quadrupole ion trap /." Full text (PDF) from UMI/Dissertation Abstracts International, 2000. http://wwwlib.umi.com/cr/utexas/fullcit?p3004273.

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36

Ketola, Raimo. "Method development in membrane inlet mass spectrometry : air analysis and desorption techniques /." Espoo : Technical Research Centre of Finland, 1998. http://www.vtt.fi/inf/pdf/publications/1998/P364.pdf.

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37

Corbin, Inge. "Analysis of Improvised Explosives by Electrospray Ionization - Mass Spectrometry and Microfluidic Techniques." FIU Digital Commons, 2016. http://digitalcommons.fiu.edu/etd/2551.

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Improvised explosives may be based on smokeless gunpowder, fertilizers, or inorganic oxidizers such as nitrate (NO3-), chlorate (ClO3-), and perchlorate (ClO4-) salts. Identification is a priority for the military and law enforcement but due to their varying physical properties and complexity, identification can be challenging. Consequently, three methods have been developed to aid in presumptive and confirmatory detection. Smokeless powder contains plasticizers, stabilizers, dyes, opacifiers, flash suppressants, and other compounds. Identification of these additives can narrow down or identif

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Rutter, Abigail Victoria. "Improving the management of lung cancer using mass spectrometry and spectroscopy techniques." Thesis, Keele University, 2016. http://eprints.keele.ac.uk/2388/.

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Lung cancer is a worldwide health problem associated with poor prognosis. The survival at 5 years remains between 5% and 15% in spite of the development of new drugs. One of the main reasons for this is the disease being diagnosed in late stages when curative treatments might not be available. Therefore, some of the most important factors within improving prognosis are both refining diagnostic techniques for early detection, and better assessing tumour response to treatment. Here lies a need for novel diagnostic tools for lung cancer. Spectroscopic and spectrometric analysis of the molecular u

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39

Jewett, Brent Nicholas. "Analysis of anionic and nonionic surfactants by liquid introduction mass spectrometry techniques." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq24859.pdf.

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Fuller, Daniel Raymond. "Probing Structure and Stability of Biomolecules with Ion Mobility-mass Spectrometry Techniques." Thesis, Indiana University, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10844168.

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<p> Ion mobility spectrometry – mass spectrometry (IMS-MS) based techniques have significantly advanced the study of both the structure and stability of biomolecules. Solution phase, biologically relevant peptide/protein conformations have been analyzed utilizing electrospray ionization (ESI) coupled to IMS-MS. The work presented here focuses on the development and application of IMS-MS for the study of the structure and stability of peptides and proteins. Structures originating in solution can be related to the biological activity of the system. Specifically, we examine the influence of

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41

Avula, Satya Girish Chandra. "Lipidomics of Algae and Human Plasma by Chromatography and Mass Spectrometry Techniques." Cleveland State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=csu1470822409.

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42

Leader, Ian Philip. "The study of personal care products using mass spectrometric techniques." Thesis, Royal Holloway, University of London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.420376.

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43

Krupicka, Vaclav. "Development of High Resolution Mass Spectrometry Techniques for Structural Analysis and Molecular Mapping of Cultural Heritage samples." Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0130.

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Ce travail de thèse propose le développement de nouvelles méthodologies en spectrométrie de masse (MS) haute résolution appliquées aux échantillons du Patrimoine Culturel (CH). En particulier, les développements se concentrent sur l’analyse protéomique top-down (TD) et l’imagerie par spectrométrie de masse MALDI (MSI), nous permettant de proposer respectivement des alternatives à l’analyse protéomique bottom-up (BU), et d’obtenir une cartographie précise des composés organiques et inorganiques des échantillons étudiés. Le premier chapitre contextualise la MS dans le domaine du patrimoine cultu

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44

Nagaraj, Nagarjuna [Verfasser], and Matthias [Akademischer Betreuer] Mann. "Developing mass spectrometry towards applications in clinical proteomics : improved sample preparation techniques and mass spectrometric methods for unbiased identification of proteome from clinical samples / Nagarjuna Nagaraj. Betreuer: Matthias Mann." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2010. http://d-nb.info/1015203140/34.

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Spikmans, Valerie. "Sensitivity and selectivity enhancement by hyphenation of nanosample separation techniques to mass spectrometry." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271038.

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Benesch, Justin Luer Paul. "Novel mass spectrometry techniques for the study of the small heat shock proteins." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614981.

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47

Pacholarz, Kamila Jolanta. "Investigation of large protein and multimeric protein complex structures with mass spectrometry techniques." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/21084.

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The biophysical properties, biological activity and function of macromolecular systems are highly dependent on their structure. Structure-activity relationships of proteins and their binding partners are critical for drug discovery, biochemical and medical research. While the gas-phase environment might present as an unusual venue from which to explore protein structure, for over the past two decades, nano-electrospray ionization (nESI) coupled to mass spectrometry (MS) has been recognized as having great potential for analysis of protein structure and protein non-covalent complexes. In conjun

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48

McBride, Ethan. "Utilizing Rapid Mass Spectrometry Techniques to Profile Illicit Drugs from Start to Finish." Thesis, University of North Texas, 2018. https://digital.library.unt.edu/ark:/67531/metadc1248455/.

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The increasingly complex world of illicit chemistry has created a need for rapid, selective means of determining the threat posed by new drugs as they are encountered by law enforcement personnel. To streamline this process, the entirety of the problem, from the production of illicit drugs all the way to the final analysis have been investigated. A series of N-alkylated phenethylamine analogues were synthesized in a shotgun method and subjected to direct-infusion analysis. A range of products were detected without the need for time-consuming purification steps, which was extended to novel phar

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Shomo, Ronald Edward II. "Soft ionization techniques for Fourier transform ion cyclotron resonance and quadrupole mass spectrometry /." The Ohio State University, 1988. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487597424138083.

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Pearce, Evan William. "The development of techniques to expand the capabilities of electrospray ionization-mass spectrometry /." May be available electronically:, 2008. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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