Academic literature on the topic 'Mast cell activation disorders'

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Journal articles on the topic "Mast cell activation disorders"

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Giannetti, Arianna, Emanuele Filice, Carlo Caffarelli, Giampaolo Ricci, and Andrea Pession. "Mast Cell Activation Disorders." Medicina 57, no. 2 (2021): 124. http://dx.doi.org/10.3390/medicina57020124.

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Background and Objectives: Mast cell disorders comprise a wide spectrum of syndromes caused by mast cells’ degranulation with acute or chronic clinical manifestations. Materials and Methods: In this review article we reviewed the latest findings in scientific papers about mast cell disorders with a particular focus on mast cell activation syndrome and mastocytosis in pediatric age. Results: Patients with mast cell activation syndrome have a normal number of mast cells that are hyperreactive upon stimulation of various triggers. We tried to emphasize the diagnostic criteria, differential diagno
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Akin, Cem. "Mast Cell Activation Disorders." Journal of Allergy and Clinical Immunology: In Practice 2, no. 3 (2014): 252–57. http://dx.doi.org/10.1016/j.jaip.2014.03.007.

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Jackson, Clayton Webster, Cristina Marie Pratt, Chase Preston Rupprecht, Debendra Pattanaik, and Guha Krishnaswamy. "Mastocytosis and Mast Cell Activation Disorders: Clearing the Air." International Journal of Molecular Sciences 22, no. 20 (2021): 11270. http://dx.doi.org/10.3390/ijms222011270.

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Mast cells are derived from hematopoietic stem cell precursors and are essential to the genesis and manifestations of the allergic response. Activation of these cells by allergens leads to degranulation and elaboration of inflammatory mediators, responsible for regulating the acute dramatic inflammatory response seen. Mast cells have also been incriminated in such diverse disorders as malignancy, arthritis, coronary artery disease, and osteoporosis. There has been a recent explosion in our understanding of the mast cell and the associated clinical conditions that affect this cell type. Some ma
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Petra, Anastasia I., Smaro Panagiotidou, Julia M. Stewart, Pio Conti, and Theoharis C. Theoharides. "Spectrum of mast cell activation disorders." Expert Review of Clinical Immunology 10, no. 6 (2014): 729–39. http://dx.doi.org/10.1586/1744666x.2014.906302.

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Picard, Matthieu, Pedro Giavina-Bianchi, Veronica Mezzano, and Mariana Castells. "Expanding Spectrum of Mast Cell Activation Disorders: Monoclonal and Idiopathic Mast Cell Activation Syndromes." Clinical Therapeutics 35, no. 5 (2013): 548–62. http://dx.doi.org/10.1016/j.clinthera.2013.04.001.

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Hsieh, Fred H. "Gastrointestinal Involvement in Mast Cell Activation Disorders." Immunology and Allergy Clinics of North America 38, no. 3 (2018): 429–41. http://dx.doi.org/10.1016/j.iac.2018.04.008.

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Broesby-Olsen, Sigurd, Melody Carter, Henrik Fomsgaard Kjaer, et al. "Pediatric Expression of Mast Cell Activation Disorders." Immunology and Allergy Clinics of North America 38, no. 3 (2018): 365–77. http://dx.doi.org/10.1016/j.iac.2018.04.009.

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Akin, Cem. "How to evaluate the patient with a suspected mast cell disorder and how/when to manage symptoms." Hematology 2022, no. 1 (2022): 55–63. http://dx.doi.org/10.1182/hematology.2022000366.

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Abstract Mast cell disorders include mastocytosis and mast cell activation syndromes. Mastocytosis is a rare clonal disorder of the mast cell, driven by KIT D816V mutation in most cases. Mastocytosis is diagnosed and classified according to World Health Organization criteria. Mast cell activation syndromes encompass a diverse group of disorders and may have clonal or nonclonal etiologies. Hematologists may be consulted to assist in the diagnostic workup and/or management of mast cell disorders. A consult to the hematologist for mast cell disorders may provoke anxiety due to the rare nature of
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Zhang, Simin, and Jonathan A. Bernstein. "Mast cell activation syndrome: Myths and realities." Allergy and Asthma Proceedings 42, no. 3 (2021): 198–204. http://dx.doi.org/10.2500/aap.2021.42.210012.

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Background: Mast cells (MCs) have been implicated in a spectrum of allergic, immunologic, and infectious inflammatory conditions that involve different organ systems. MC activation can occur through several different surface receptors other than the well known IgE mediated pathway. Methods: We use two representative case reports from our practice to summarize what is currently known about MCAS disorders (reality) so that the clinician can more easily differentiate these conditions from other complex unexplained conditions that are being associated with MC activation (myth). Results: Many compl
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Friesen, Hunter, Meenal Singh, Vivekanand Singh, Jennifer V. Schurman, and Craig A. Friesen. "A Survey of Methodologies for Assessing Mast Cell Density and Activation in Patients with Functional Abdominal Pain Disorders." Gastrointestinal Disorders 3, no. 4 (2021): 142–55. http://dx.doi.org/10.3390/gidisord3040016.

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The aim was to assess methods utilized in assessing mast cell involvement in functional abdominal pain disorders (FAPDs), specifically to describe variability in methods utilized to assess both mast cell density and activation and determine if a consensus exists. After a literature search identified 70 manuscripts assessing mast cell density, data were extracted including FAPD diagnosis, site of biopsy, selection of microscopic fields analyzed, selection of mucosal region analyzed, method of mast cell identification, method to assess mast cell density, and if performed, method to assess mast c
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Dissertations / Theses on the topic "Mast cell activation disorders"

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Endoh, Ikuko Medical Sciences Faculty of Medicine UNSW. "New mechanisms of regulation of mast cell activation." Publisher:University of New South Wales. Medical Sciences, 2008. http://handle.unsw.edu.au/1959.4/42937.

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Mast cells (MCs) play a central role in inflammation by releasing mediators following activation. S100A8 and S100A9 are abundantly expressed in inflammatory sites such as asthmatic lung, sunburnt skin and atherosclerosis where MCs are involved in pathogenesis; roles of S100A8 in MC function are undetermined. The aims of this thesis were to determine effects of S100A8 on MC activation, particularly provoked by IgE and UVB. Initially, effects of UVB on MC activation were investigated as detailed functions were unclear. Cord blood-derived human mast cells (CBMCs) were treated in vitro with varyin
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Koranteng, Rachael Darkoa. "Effects of nitric oxide on mast cell activation." Thesis, University of Liverpool, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343761.

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Collmann, Emilie. "Role of phosphoindositide 3-kinases in mast cell activation /." [S.l.] : [s.n.], 2009. http://edoc.unibas.ch/diss/DissB_8779.

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Versani, Maheshkumar Premji. "The role of phospholipase A2 in mast cell activation." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286756.

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Alic, Arna. "Involvement of proteases and kinases in mast cell activation." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.251972.

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Faber, Travis. "ADAM10: a Novel Regulator of Mast Cell Function and Activation." VCU Scholars Compass, 2012. http://scholarscompass.vcu.edu/etd/354.

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In this study we show, to our knowledge, the first description of the role ADAM10 plays on mast cells. ADAM10 is abundantly expressed on mast cells both in vitro and in vivo. Its expression is inhibited by IL-10, a suppressive cytokine. siRNA depletion of ADAM10 on bone marrow-derived mast cells (BMMC) caused decreased IL-6 production following IgE cross-linking and also impaired BMMC stem cell factor (SCF)-induced migration through collagen IV. Mast cells and T helper cells (Th cells) in the peritoneum were reduced in ADAM10 KO mice. In addition, ADAM10 KO BMMC produced significantly less of
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Clements, Ruth Jocelyn Muriel. "Mast cell recruitment and activation as measures of cyathostomin burden." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/15853.

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Cyathostomins are potentially life threatening parasitic nematodes of adult horses and are highly prevalent worldwide. Infected animals may be asymptomatic or show clinical signs of weight loss, diarrhoea and colic. Third and fourth stage larvae spend a large proportion of their lifecycle encysted in the large intestinal wall where they cannot currently be detected ante mortem. Mast cells are commonly found at interfaces to the external environment, such as the rectum, and these cells and the proteinases they produce have been implicated in protective host immune responses against nematode inf
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Haaster, Charles Marie Catharine Joseph van. "Mast cell activation and mediator release implications for the cardiovascular system /." [Maastricht : Maastricht : Rijksuniversiteit Limburg] ; University Library, Maastricht University [Host], 1996. http://arno.unimaas.nl/show.cgi?fid=6684.

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Hallgren, Jenny. "The role of heparin in the activation of mast cell tryptase /." Uppsala : Dept. of Molecular Biosciences, Swedish Univ. of Agricultural Sciences, 2004. http://epsilon.slu.se/v179.pdf.

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Chernushevich, Oksana I. "THE EFFECT OF DEXAMETHASONE ON IL-33-MEDIATED MAST CELL ACTIVATION." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3772.

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Dexamethasone has been shown to inhibit IgE-mediated mast cell activation, and the present research investigated its role in suppressing IL-33-mediated mast cell activation. We have found that micromolar concentrations of Dexamethasone are capable of suppressing IL-33-mediated mast cell cytokine production, on several genetic backgrounds, and in not only bone marrow derived mast cells, but also peritoneal mast cells. Intracellular staining demonstrated that Dexamethasone significantly reduces expression of the IL-33 receptor, T1/ST2, in mast cells; however, the cytokine suppression is independ
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Books on the topic "Mast cell activation disorders"

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Marc, Feldmann, Maini R. N, Woody James N, and United States. Naval Medical Research and Development Command., eds. T-cell activation in health and disease: Disorders of immune regulation infection and autoimmunity : papers from an international meeting in Oxford, UK, in September 1988. Academic Press, 1989.

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O'Brien, Roselle P. Understanding MCD: A Therapist's Guide to Long-COVID, Mast Cell Activation Syndrome , Mast Cell Disorders , Chemical Sensitivities & Environmental Illness. CELA Publishing, 2024.

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MASTEJ, Morris. Mast Cell Activation Syndrome: The Step by Step Nutritional Guide to Reversing and Managing Systemic Mastocytosis or Mast Cell Activation Syndrome Disorder. Independently Published, 2022.

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Mast Cell Activation Syndrome Manual: The Ultimate Guide for the Treatment of Mast Cell Activation Syndrome Disease or Disorder to End Chronic Illness. Independently Published, 2021.

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Hank, Jackie. Mast Cell Activation Syndrome Explained: The Step by Step Guide on Healing and Treatment of Systemic Mastocytosis or Mast Cell Activation Syndrome Disorder. Independently Published, 2021.

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HOWARD, Enedino. Mast Cell Activation Syndrome Diet Cookbook. Independently Published, 2022.

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Walker, Amber. Mast Cells United: A Holistic Approach to Mast Cell Activation Syndrome. Amber Walker, 2019.

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Urz, Ryan, and Jennifer Leopoldt-Roop. Mast Cells United: A Holistic Approach to Mast Cell Activation Syndrome. Walker, Amber, 2019.

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Blank, Ulrich, and Marc Benhamou, eds. Deciphering new molecular mechanisms of mast cell activation. Frontiers Media SA, 2014. http://dx.doi.org/10.3389/978-2-88919-186-4.

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Mast Cell Activation Syndrome: A Perfect Guide to Dealing with Mast Cell Activation Syndrome, Meal Plan and Recipes Included. Independently Published, 2022.

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Book chapters on the topic "Mast cell activation disorders"

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Gniadecki, Robert, Minakshi Taparia, Jean Deschenes, Jori Hardin, and Etienne Mahe. "Mastocytosis and Mast Cell Activation Disorders." In Diseases of Blood and Skin. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-65292-9_14.

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Einsele, Hermann, and Ibrahim Yakoub-Agha. "Management of Other Toxicities." In The EBMT/EHA CAR-T Cell Handbook. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94353-0_30.

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AbstractSecondary haemophagocytic lymphohistiocytosis (sHLH) or macrophage activation syndrome (MAS) is a life-threatening hyperinflammatory syndrome that can occur in patients with severe infections, e.g., COVID-19 infection, malignancy or autoimmune diseases. It is also a rare complication of allogeneic haematopoietic cell transplantation (allo-HCT), independent of the underlying trigger mechanism or underlying disorders associated with high mortality. There have been increasing reports of sHLH/MAS occurrence following CAR-T cell therapy, but its differentiation from cytokine release syndrom
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Girnius, Andrea, and Saulius Girnius. "Mast Cell Activation Disease." In Consults in Obstetric Anesthesiology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-59680-8_102.

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Bahri, Rajia, and Silvia Bulfone-Paus. "Mast Cell Activation Test (MAT)." In Basophils and Mast Cells. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0696-4_19.

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Grattan, Clive E. H. "Mast Cell Activation Syndrome (MCAS)." In Postural Tachycardia Syndrome. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-54165-1_21.

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Cruse, Glenn, Alasdair M. Gilfillan, and Daniel Smrz. "Flow Cytometry-Based Monitoring of Mast Cell Activation." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_23.

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Haidl, Ian D., and Jean S. Marshall. "Human Mast Cell Activation with Viruses and Pathogen Products." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_12.

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Dráber, Pavel, and Petr Dráber. "Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_14.

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Kalesnikoff, Janet, and Stephen J. Galli. "Anaphylaxis: Mechanisms of Mast Cell Activation." In Anaphylaxis. KARGER, 2010. http://dx.doi.org/10.1159/000315937.

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Feteih, Abeer, Farida Almarzooqi, Geneviève Genest, Michael Fein, Hoang Pham, and Moshe Ben-Shoshan. "Mastocytosis and Mast Cell Activation Syndromes." In The Manual of Allergy and Clinical Immunology. CRC Press, 2021. http://dx.doi.org/10.1201/9781003174202-15.

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Conference papers on the topic "Mast cell activation disorders"

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Hammond, T. C., I. O. Emeruwa, S. R. Swain, S. M. Larson, and M. C. Castells. "Life-threatening Mast Cell Activation and Anaphylaxis in Mast Cell Leukemia and the Role of Omalizumab." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5294.

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Macedo, Rafael Bassara, Pedro Giavina-Bianchi, Diogo Souza Domiciano, and André Silva Franco. "ASSOCIATION BETWEEN HYPERMOBILITY, DYSAUTONOMIA, AND MAST CELL DISORDERS A CASE REPORT." In XLI Congresso Brasileiro de Reumatologia. Sociedade Brasileira de Reumatologia, 2024. https://doi.org/10.47660/cbr.2024.2154.

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Kim, Dae Yong, Yu Hua Quan, Bum Soo Park, Gwan Ui Hong, and Jai Youl Ro. "8-hydroxydeoxyguanosine Ameliorates Mast Cell Activation Through Gamma Irradiation Exposure." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a1430.

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Umarova, Bella. "ASSOCIATION OF MAST CELL ACTIVATION WITH PROCESSES OF INFLAMMATORY AND BLOOD COAGULATION." In XVIII INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2022. http://dx.doi.org/10.29003/m2966.sudak.ns2022-18/351-352.

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Goossens, Janne, Toon Ieven, Ellen Dilissen, et al. "Human mast cell differentiation optimization to study MRGPRX2-induced activation in vitro." In ERS Lung Science Conference 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/23120541.lsc-2022.63.

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Brown, JM, EJ Swindle, and DD Metcalfe. "Mast Cell Activation by Silica Is Dependent on Expression of SR-BI/II." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a3705.

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Katre, Mahesh, Abhidhamma Kaninde, and Harsha Bilolikar. "154 Food allergy with Idiopathic anaphylaxis and mast cell activation syndrome diagnostic challenge." In 10th Europaediatrics Congress, Zagreb, Croatia, 7–9 October 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-europaediatrics.154.

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Swindle, Emily J., Cornelia Blume, Stephen T. Holgate, and Donna E. Davies. "Differentiated Bronchial Epithelial Cells Suppress Antigen-Mediated Mast Cell Activation Following Co-Culture." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5736.

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Kosanovic, Djuro, Bhola K. Dahal, Josef Messinger, et al. "Pulmonary Mast Cell Activation And Increased Chymase In Patients With Pulmonary Hypertension And Fibrosis." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a6427.

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Tiotiu, Angelica, Yusef Badi, Nazanin Zounemat Kermani, et al. "Differential mast cell activation by transcriptomic signature analysis in the U-BIOPRED severe asthma cohort." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.3827.

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Reports on the topic "Mast cell activation disorders"

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Hirankarn, Nattiya, Tanapat Palaga, Yingyos Avihingsanon, and Pimpayao Sodsai. The characterization of the two new genes, PTGS2 and PSN2 involving in the T lymphocyte apoptosis of lupus patients: Role of genetic polymorphism and epigenetic alteration. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.28.

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Systemic lupus erthematosus (SLE) is a prototype of autoimmune disease characterized by tissue deposition of autoantibody immune complex formation. However, etiology of disease remains unclarified. Defects of T lymphocytes lead to loss of immunological tolerance and support autoantibody production suggested that they may consistently have a central role in pathogenesis of SLE. Notch signaling is an evolutionarily conserved pathway responsible for thymocyte development, activation, proliferation, differentiation and T cell functions. Several evidences suggest Notch signaling involvement in auto
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