Relevant bibliographies by topics / Mast cells

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Mast cells'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Mast cells"

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Holgate, S. T. "Mast cells." Clinical Experimental Allergy 21, no. 5 (1991): 633–34. http://dx.doi.org/10.1111/j.1365-2222.1991.tb00864.x.

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Rao, Kavitha N., and Melissa A. Brown. "Mast Cells." Annals of the New York Academy of Sciences 1143, no. 1 (2008): 83–104. http://dx.doi.org/10.1196/annals.1443.023.

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Swedenborg, Jesper, Mikko I. Mäyränpää, and Petri T. Kovanen. "Mast Cells." Arteriosclerosis, Thrombosis, and Vascular Biology 31, no. 4 (2011): 734–40. http://dx.doi.org/10.1161/atvbaha.110.213157.

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WEBER, SYLVIA, SABINE KRÜGER-KRASAGAKES, JÜRGEN GRABBE, TORSTEN ZUBERBIER, and BEATE M. CZARNETZKI. "MAST CELLS." International Journal of Dermatology 34, no. 1 (1995): 1–10. http://dx.doi.org/10.1111/j.1365-4362.1995.tb04366.x.

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Shea-Donohue, Terez, Jennifer Stiltz, Aiping Zhao, and Luigi Notari. "Mast Cells." Current Gastroenterology Reports 12, no. 5 (2010): 349–57. http://dx.doi.org/10.1007/s11894-010-0132-1.

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Schlereth, Tanja, and Frank Birklein. "Mast Cells." Anesthesiology 116, no. 4 (2012): 756–57. http://dx.doi.org/10.1097/aln.0b013e31824bb143.

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Metcalfe, D. D., D. Baram, and Y. A. Mekori. "Mast cells." Physiological Reviews 77, no. 4 (1997): 1033–79. http://dx.doi.org/10.1152/physrev.1997.77.4.1033.

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Mast cells are found resident in tissues throughout the body, particularly in association with structures such as blood vessels and nerves, and in proximity to surfaces that interface the external environment. Mast cells are bone marrow-derived and particularly depend upon stem cell factor for their survival. Mast cells express a variety of phenotypic features within tissues as determined by the local environment. Withdrawal of required growth factors results in mast cell apoptosis. Mast cells appear to be highly engineered cells with multiple critical biological functions. They may be activat
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Wershil, Barry K., and Stephen J. Galli. "Gastrointestinal Mast Cells." Gastroenterology Clinics of North America 20, no. 3 (1991): 613–27. http://dx.doi.org/10.1016/s0889-8553(21)00573-2.

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Norris, Alan. "Targeting mast cells." Expert Opinion on Investigational Drugs 13, no. 7 (2004): 739–41. http://dx.doi.org/10.1517/13543784.13.7.739.

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Mueller, Kristen L. "Mast Cells Revisited." Science 335, no. 6064 (2012): 14.3–14. http://dx.doi.org/10.1126/science.335.6064.14-c.

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Dissertations / Theses on the topic "Mast cells"

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Dacre, Kirstie Jane. "Involvement of mast cells and mast cell serine proteinases in equine heaves." Thesis, University of Edinburgh, 2006. http://hdl.handle.net/1842/29721.

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Mast cells release potent mediators upon degranulation, including serine proteinases. These proteinases play a pivotal role in the pathogenesis of human asthma. Due to the similarities between human asthma and equine heaves, a similar role for the mast cell in equine heaves is proposed. Clinical heaves horses had significantly increased BALF tryptase concentrations compared to controls or heaves horses in remission, whereas BALF tryptase concentrations of controls and heaves horses in remission did not significantly differ. Horses with other pulmonary diseases also had significantly elevated B
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Leskinen, Markus. "Mast cell-mediated apoptosis of smooth muscle cells and endothelial cells." Helsinki : University of Helsinki, 2003. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/leskinen/.

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Crummy, F. "Adenosine, mast cells and asthma." Thesis, Queen's University Belfast, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403238.

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Huntley, John Frederick. "Mast cells and intestinal nematodiasis." Thesis, University of Edinburgh, 1991. http://hdl.handle.net/1842/15070.

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Specific enzyme-linked immunosorbent assays (ELISA) for rat mast cell proteinase I and II (RMCP I and II), intestinal mast cell proteinase (IMCP) and sheep mast cell proteinase (SMCP) were developed. Sheep serum or lymph contained potent inhibitory factors which interfered with the ELISA for SMCP, whereas little or no effect was demonstrated in the rodent ELISA by homologous serum. Secretion of SMCP into gastric lymph was noted in immune sheep following oral challenge with <i>Ostertagia circumcincta</i>. Development of immunity to <i>Haemonchus contortus</i> in sheep, expressed as the ability
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Alswied, Abdullah M. "Calcium signalling in mast cells." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:cc8f5f8b-5cab-4391-bce3-9541ab371002.

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Mast cells play a central role in many allergic and in ammatory conditions. These cells are activated following an intracellular rise in calcium, such as that which occurs after the activation of cell-surface receptors. One such important receptor is cysteinyl leukotriene (CysLT) receptor type 1 (CysLT1), which is activated by lipid mediators such as CysLTs LTC4, LTD4, and LTE4. CysLT1 stimulation leads to the hydrolysis of membrane phospholipids such as phosphatidylinositol 4 5-bisphosphate (PIP2) via phospholipase C-β , which results in the generation of diacylglycerol and inositol trisphosp
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Roy, Ananya. "Mast Cells as Sentinels : Role of serglycin and mast cell proteases in infection and inflammation." Doctoral thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-173508.

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Mast cells (MCs), normally classified into connective tissue MCs and mucosal MCs, are highly granulated cells found in the interface between the interior and the exterior environment of our body, e.g. skin, airways and gastro-intestinal tract. They react to bacteria, parasites, viruses, and allergens by degranulation and release of premade and newly synthesized inflammatory mediators. The MC-proteases (tryptases, chymases and carboxypeptidase A), histamine and serglycin (SG) proteoglycans are premade mediators. Among these, SG is also expressed in a variety of other immune and non-immune cells
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Friend, Reuben. "SNARE proteins in human mast cells." Thesis, University of Sheffield, 2013. http://etheses.whiterose.ac.uk/5177/.

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Mast cells form an integral part of both innate and adaptive immunity; they help to orchestrate the inflammatory immune response through the release of a variety of inflammatory mediators. Adverse reaction to allergens can lead to activation of mast cells, causing degranulation and release of a range of pro-inflammatory mediators contributing to the onset of allergy. The most studied activation pathway in the adaptive immune response of mast cells is through the Immunoglobulin E (IgE) cell surface receptor FceRI. Crosslinking of FceRI leads to degranulation and de novo synthesis of mediators.
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Tree-Booker, Claire. "TRPC channels in human mast cells." Thesis, University of Sheffield, 2011. http://etheses.whiterose.ac.uk/1927/.

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Mast cells have an important role in the immune system, but they are centrally involved in the pathophysiology of asthma, along with a number of other allergic diseases including rhinitis, eczema and irritable bowel disease (Metcalfe et al., 1997; Beaven, 2009). In the allergic response they are activated by IgE binding to high affinity receptors and subsequent crosslinking by antigen. A rise in intracellular Ca2+ is required for mast cells to become activated and release mediators into the surrounding areas, which give rise to the symptoms of allergic disease (Gilfillan & Tkaczyk, 2006). Eluc
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Lin, Tzu-Yin. "The world according to mast cells – the role of Kit in normal and neoplastic canine mast cells." The Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=osu1189098916.

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Wang, Yiyu [Verfasser]. "Analysis of mast cells and mast cell-mediator-related histological features in cholinergic urticaria / Yiyu Wang." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2019. http://d-nb.info/1189139715/34.

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Books on the topic "Mast cells"

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Krishnaswamy, Guha, and David S. Chi, eds. Mast Cells. Humana Press, 2005. http://dx.doi.org/10.1385/1592599672.

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Hughes, Michael R., and Kelly M. McNagny, eds. Mast Cells. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-1568-2.

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Dvorak, Ann M. Human Mast Cells. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74145-6.

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Guha, Krishnaswamy, and Chi David S, eds. Mast cells: Methods and protocols. Humana Press, 2006.

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Gibbs, Bernhard F., and Franco H. Falcone, eds. Basophils and Mast Cells. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0696-4.

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Gibbs, Bernhard F., and Franco H. Falcone, eds. Basophils and Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1173-8.

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Ribatti, Domenico, and Enrico Crivellato. Mast Cells and Tumours. Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-1469-4.

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Foundation, Novartis. Mast Cells and Basophils. John Wiley & Sons, Ltd., 2006.

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D, Befus, Bienenstock John, Denburg Judah A, and Mast Cell Symposium (1985 : Alton, Ont.), eds. Mast cell differentiation and heterogeneity. Raven Press, 1986.

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Holgate, S. T., ed. Mast Cells, Mediators and Disease. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-1287-8.

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Book chapters on the topic "Mast cells"

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Ghably, Jack, Hana Saleh, Harsha Vyas, Emma Peiris, Niva Misra, and Guha Krishnaswamy. "Paul Ehrlich’s Mastzellen: A Historical Perspective of Relevant Developments in Mast Cell Biology." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_1.

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Bandara, Geethani, Dean D. Metcalfe, and Arnold S. Kirshenbaum. "Growth of Human Mast Cells from Bone Marrow and Peripheral Blood-Derived CD34+ Pluripotent Hematopoietic Cells." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_10.

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Lorentz, Axel, Gernot Sellge, and Stephan C. Bischoff. "Isolation and Characterization of Human Intestinal Mast Cells." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_11.

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Haidl, Ian D., and Jean S. Marshall. "Human Mast Cell Activation with Viruses and Pathogen Products." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_12.

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Kawakami, Yuko, and Toshiaki Kawakami. "Basic Techniques to Study FcεRI Signaling in Mast Cells." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_13.

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Dráber, Pavel, and Petr Dráber. "Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_14.

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Rios, Eon J., and Janet Kalesnikoff. "FcεRI Expression and Dynamics on Mast Cells." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_15.

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Westerberg, Christine Möller, Maria Ekoff, and Gunnar Nilsson. "Regulation of Mast Cell Survival and Apoptosis." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_16.

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Geldman, Alexander, and Catherine J. Pallen. "Protein Tyrosine Phosphatases in Mast Cell Signaling." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_17.

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Maltby, Steven, Maximilian Plank, Catherine Ptaschinski, Joerg Mattes, and Paul S. Foster. "MicroRNA Function in Mast Cell Biology: Protocols to Characterize and Modulate MicroRNA Expression." In Mast Cells. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1568-2_18.

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Conference papers on the topic "Mast cells"

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Farha, Samar, Jacqueline Sharp, Kewal Asosingh, et al. "Mast Cells In Pulmonary Arterial Hypertension." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4949.

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Reid, Alicia C., Arul Veerappan, Colleen Achong, Nathan O'Connor, and Randi B. Silver. "MAST CELLS, MAST CELL RENIN AND LOCAL ANGIOTENSIN II IN MONOCROTALINE-INDUCED PULMONARY ARTERIAL HYPERTENSION." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6329.

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Michels, NM, HW Chu, SC LaFasto, S. Case, M. Minor, and RJ Martin. "Mast Cells MediateMycoplasma PneumoniaeClearance after Acute Infection." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a3241.

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Paßlick, David, Hendrik Beckert, and Sebastian Reuter. "Mast Cells and SiO2 Nanoparticles – a Suitable Interaction?" In Herbsttagung der Sektion Zellbiologie in der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1678387.

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Umarova, Bella. "MAST CELLS: ROLE IN PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES." In XV International interdisciplinary congress "Neuroscience for Medicine and Psychology". LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m586.sudak.ns2019-15/416-417.

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Ntaliarda, G., I. Lilis, V. Papaleonidopoulos, et al. "A requirement for mast cells in lung adenocarcinoma." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.lsc-1144.

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Umarova, B. "MAST CELLS FROM INFLAMMATORY STIMULUS TO IMMUNE RESPONSE." In XVII INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2021. http://dx.doi.org/10.29003/m2358.sudak.ns2021-17/379.

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Messemaker, Tobias, Jolien Suurmond, Kim L. Habets, et al. "03.19 Mast cells are reprogrammed through repeated triggering." In 37th European Workshop for Rheumatology Research 2–4 March 2017 Athens, Greece. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2016-211049.19.

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Dahal, Bhola K., Djuro Kosanovic, Raj K. Savai, et al. "Role Of Mast Cells In Experimental Pulmonary Hypertension." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6330.

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Berlin, Frida, Sofia Mogren, Lena Uller, and Cecilia Andersson. "Mast cell chymase induce functional and morphological alterations in bronchial epithelial cells." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa830.

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Reports on the topic "Mast cells"

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Theoharides, Theoharis. Role of Mast Cells in Mammary Gland Carcinogenesis. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada430366.

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Ho, Andrea Ming-Wei. Capillary electrophoretic study of individual exocytotic events in single mast cells. Office of Scientific and Technical Information (OSTI), 1999. http://dx.doi.org/10.2172/348903.

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Ivanova, Ivelina G., Nikola S. Tomov, Nikolay D. Dimitrov, Dimitrinka Y. Atanasova, Dimitar P. Sivrev, and Ivaylo S. Stefanov. Distribution of Serotonin Positive Mast Cells in the Intrapulmonary Airways of Rats. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2019. http://dx.doi.org/10.7546/crabs.2019.02.14.

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กัลล์ประวิทธ์, มาริษศักร์, ไพวิภา สุทธิพงศ์, ชนินทร์ กัลล์ประวิทธ์ та จุรี ประมัตต์วินัย. การใช้ตาข่ายไนล่อนในการแก้ไขไส้เลื่อนที่สะดือสุกร : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 1988. https://doi.org/10.58837/chula.res.1988.40.

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สุกรที่มีไส้เลื่อนที่สะดือจำนวน 39 ตัว ได้รับการรักษาทางศัลยกรรมโดยใช้ตาข่ายไนล่อนปิดช่องปากถุงไส้เลื่อน (Hernial ring) จำนวน 30 ตัว และโดยใช้ไหมไนล่อนเย็บแบบ “vest-over-pants” จำนวน 9 ตัว ใช้สุกร 20 ตัว สำหรับศึกษาปฏิกิริยาการตอบสนองของเนื้อเยื่อร่างกาย (Tissue reaction) ต่อตาข่ยไนล่อนภายหลังผ่าตัด 2, 4, 6 และ 8 สัปดาห์ ในสุกรระยะเวลาละ 5 ตัว พบ fibrous connective tissue, giant cells และ mast cells ในบริเวณรอบ ๆ เส้นไหมไนล่อนทุกระยะที่ศึกษาในประมาณที่ไม่แตกต่างกัน ในการเปรียบเทียบผลการรักษาแบบใช้ตาข่ายไนล่อนในสุกรที่เหลือ 10 ตัว กับแบบใช้ไหมไนล่อนเย็บแบบ “vest-over-pants” ในสุกร 9 ตัว โดยใช้
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Noga, Edward J., Angelo Colorni, Michael G. Levy, and Ramy Avtalion. Importance of Endobiotics in Defense against Protozoan Ectoparasites of Fish. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7586463.bard.

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Infectious disease is one of the most serious causes of economic loss in all sectors of aquaculture. There is a critical need to understand the molecular basis for protection against infectious disease so that safer, more reliable and more cost-effective strategies can be designed for their control. As part of this effort, the major goal of our BARD project was to determine the importance of endobiotics as a defense against protozoan ectoparasites in fish. Endobiotics, or antimicrobial polypeptides, are peptides and small proteins that are increasingly recognized as having a vital role in the
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พฤกษานานนท์, กำธร, รัฐจักร รังสิวิวัฒน์, ปราณี นำชัยศรีค้า, วิชชุดา อานนท์กิจพานิช та ประมวล วีรุตมเสน. เซลล์ต้นกำเนิดตัวอ่อน : รายงานวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2008. https://doi.org/10.58837/chula.res.2008.24.

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เนื่องจากการใช้เซลล์พี่เลี้ยงที่แยกได้จากตัวอ่อนของหนู เพื่อเลี้ยงเซลล์ต้นกำเนิดตัวอ่อนมนุษย์ มีความเสี่ยงต่อการปนเปื้อนของเชื้อโรคที่มาจากหนู ดังนั้น การศึกษาวิจัยจึงมีจุดประสงค์เพื่อสร้างเซลล์ต้นกำเนิดตัวอ่อนมนุษย์โดยใช้เซลล์พี่เลี้ยงที่แยกได้จากคน เซลล์พี่เลี้ยงชนิดไฟโบรบลาสแยกได้จากผิวหนังบริเวณหน้าท้องของผู้หญิงที่เข้ารับการผ่าตัดทำคลอด ใช้ตัวอ่อนที่เกิดการปฎิสนธิภายนอกร่างกาย และผ่านการแช่แข็งจำนวนสิบตัวอ่อน เพื่อสร้างเซลล์ต้นกำเนิดตัวอ่อนมนุษย์กลุ่ม อินเนอร์เซลล์แมส (inner cell mass: ICM) ของตัวอ่อน 8 ตัวอ่อนถูกแยกออกจากเซลล์โทรเฟคโตเดิร์ม (trophectoderm: TE) โดยการใช้แท่งแก้วไปเปตขนาดเ
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แก้วกิติณรงค์, กมล, та นิพนธ์ อุดมสันติสุข. บทบาทของ MAIT cells ในการควบคุมการติดเชื้อแบคทีเรีย Mycobacterium tuberculosis : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2016. https://doi.org/10.58837/chula.res.2016.28.

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วัณโรค (Tuberculosis) เป็นสาเหตุหลักของการเสียชีวิตจากโรคติดเชื้อของประชากรทั่วโลก (1) วัณโรคเกิดจากการติดเชื้อแบคทีเรีย Mycobacterium tuberculosis ภูมิต้านทานของร่างกายที่มีต่อเชื้อ Mycobacterium tuberculosis ประกอบด้วยเซลล์จากส่วนของ innate immunity และ adaptive immunity ในส่วนของ adaptive immunity กลุ่มของ T cells ที่มีส่วนสำคัญ ได้แก่ ทั้ง conventional T cells (ทั้ง CD8+ และ CD4+) และ non-conventional T cells (MAIT, NKT, CD1-restricted T cells) (2) MAIT (Mucosal-associated invariant T) cells จัดอยู่ในกลุ่มของ non-conventional T cells ที่พบได้ปริมาณมากตามเยื่อบุของร่างกาย รวมถึงปอด (3) นอกจ
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Phisalaphong, Muenduen. Development of cell carrier for improved productivity of continuous ethanol fermentation by Saccharomyces cerevisiae. Chulalongkorn University, 2010. https://doi.org/10.58837/chula.res.2010.51.

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The production of a renewable energy from biomass, such as ethanol by fermentation, has received special attention as a consequence of the world energy crisis. Nowadays, gasohol E-10, a mixture of 10% ethanol and 90% gasoline has been widely used in vehicles in Thailand and there is an attempt to promote the use of E-20 or E-85 in the vehicles in the near future. Ethanol fermentation by conventional batch suffers from various constrains such as, low cell density and rather time consuming. Although continuous fermentation by suspended cell culture can be used to speed up the process, it is more
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Thongtan, Thananya, Poonlarp Cheepsunthorn, and Kiat Ruxrungtham. An analysis and studies expression of receptor molecule on microglia cells to inhibits infection of the cells from Japanese encephalitis virus : Research report (Year 2009). Chulalongkorn University, 2009. https://doi.org/10.58837/chula.res.2009.14.

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Japanese encephalitis virus (JEV), a mosquito-borne flavivirus, is a major cause of viral encephalitis in Asia. Even though the principle target cells for JEV in the central nervous system are neurons, the microglia is activated in response to JEV infection. This research aimed to investigate the relationship between JEV and microglial cells. The percentage of JEV infectivity in mouse microglial (BV-2) cell line at 8, 15 and 24 hr post infection was determined by flow cytometry. It was found that the percentage of infected cells were approximately 53.5, 71.3 and 83.6 respectively. The JEV bind
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พฤกษานานนท์, กำธร, รัฐจักร รังสิวิวัฒน์, ปราณี นำชัยศรีค้า, วิชชุดา อานนท์กิจพานิช та ประมวล วีรุตมเสน. เซลล์ต้นกำเนิดตัวอ่อน : รายงานวิจัย. คณะแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2007. https://doi.org/10.58837/chula.res.2007.24.

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เซลล์ต้นกำเนิดตัวอ่อนมนุษย์ เป็นเซลล์ที่แยกได้จากเซลล์ของตัวอ่อนในระยะก่อนฝังตัว เซลล์ ต้นกำเนิดตัวอ่อนแสดงคุณสมบัติที่สำคัญคือ สามารถแบ่งตัวได้โดยไม่มีขีดจำกัด และสามารถเปลี่ยนแปลงไปเป็นเซลล์ทุกชนิดที่พบในร่างกาย ปัจจุบันเซลล์ต้นกำเนิดตัวอ่อนถูกสร้างขึ้นในห้องปฏิบัติการในหลายๆ ประเทศ ประเทศไทยมีศักยภาพเพียงพอที่จะสร้างเซลล์ต้นกำเนิดมนุษย์เพื่อใช้ในการวิจัยทางด้านชีววิทยาโมเลกุล การพัฒนาของตัวอ่อน หรือเพื่อการรักษาโดยใช้เซลล์ การวิจัยนี้มีจุดมุ่งหมายที่จะสร้างสายพันธุ์เซลล์ต้นกำเนิดจากตัวอ่อนมนุษย์ โดยแบ่งการศึกษาออกเป็นสองระยะ ระยะแรกศึกษาสภาวะที่เหมาะสมที่คาดว่าน่าจะสามารถสร้างเซลล์ต้นกำเนิด
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