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1

Rappe, Katrin Steffanie. "Evaluación de la osteointegración y osteoconducción de implantes de titanio poroso bioactivos: valoración con microscopía electrónica de retrodispersión en un modelo de implantación ortotópica en conejos." Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/669592.

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En los últimos años, la ciencia de los biomateriales aplicada a los sustitutos óseos se ha centrado en la investigación de nuevos implantes elaborados con materiales que, además de presentar una estructura de poros interconectados esencial para un adecuado crecimiento óseo que asegure el anclaje del implante, presenten también unas óptimas propiedades biomecánicas. Los estudios más recientes se centran en el desarrollo de implantes a base de metales porosos bioactivos, como el titanio, que presentan buenas propiedades mecánicas al soportar adecuadamente las condiciones de carga. Diversos estud
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Eghtesadi, Neda. "Mechanical properties of resorbable PCL/FastOs® BG composite materials." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/13636.

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Mestrado em Materiais e Dispositivos Biomédicos<br>Bioresorbable composites nowadays play an increasingly important role in the modern medicine, especially in orthopaedics for the fixation of bone fractures and tendons. Contrarily to the metallic counterparts, they prevent a second surgical operation to remove them, because they will be gradually integrated in the bone tissues. Finding ways to improve their physical and mechanical properties to better fit the intended specific conditions and environments has been a goal in many researches. It has already established that size, shape, as
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3

Takadama, Hiroaki. "MECHANISM OF APATITE FORMATION ON BIOACTIVE MATERIALS." 京都大学 (Kyoto University), 2001. http://hdl.handle.net/2433/150685.

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4

Azevedo, Maria Manuel Goncalves. "Hypoxia-mimicking bioactive materials for skeletal tissue engineering." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/9005.

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The next generation of regenerative medicine solutions will depend on smart materials that can activate “self-healing” mechanisms. Cells respond to changes in pO2 through a hypoxia-sensing pathway, the HIF-1 pathway, which activates numerous processes necessary for bone and cartilage development and for normal tissue repair. Control of these processes is critical in tissue engineering (TE), therefore this thesis aimed to develop novel hypoxia-mimicking materials for skeletal TE. Resorbable bioactive glasses (BG) were chosen as the delivery system for a hypoxia-stimulating ion, Co2+. Two series
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Kimu, Hyonmin. "Design of Bioactive Materials with High Fracture Toughness." Kyoto University, 1997. http://hdl.handle.net/2433/202290.

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6

Eriksson, Alexander. "Bioactivity testing of dental materials." Thesis, Uppsala universitet, Tillämpad materialvetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-382042.

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Ever since Hench et al. first discovered bioactive glass in 1969, extensive interest was created because of the materials ability to chemically bond with living tissue. In this project the bioactivity of three different compositions of the bioactive glass Na2O-CaO-SiO2 have been studied. The compositions of the different glasses were A (25% Na2O, 25% CaO and 50% SiO2), B (22.5% Na2O, 22.5% CaO and 55% SiO2) and C (20% Na2O, 20% CaO and 60% SiO2). Their bioactivity was tested through biomimetic evaluation, in this case by soaking samples of each glass in simulated body fluid (SBF) and phosphate
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7

Brown, Lindsey. "The role of silicon in osteoinduction by bioactive materials." Thesis, Queen Mary, University of London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429145.

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8

Ho, Emily Marcolongo Michele S. "Engineering bioactive polymers for the next generation of bone repair /." Philadelphia, Pa. : Drexel University, 2005. http://dspace.library.drexel.edu/handle/1860/474.

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9

Perrin, Eloïse. "Elaboration et caractérisation d'un biomatériau bioactif et résorbable à base de polylactide et de verre bioactif." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSEI110.

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Cette étude porte sur le développement et la caractérisation d’un biomatériau d’ostéosynthèse bioactif, biorésorbable et présentant une tenue mécanique la plus élevée possible. Il a pour vocation de favoriser la repousse osseuse tout en remplaçant temporairement les fonctions mécaniques de l’os. Le matériau, élaboré à base d’un polyacide lactique et de verre bioactif, doit pouvoir être transformé par injection moulage de manière à obtenir des formes complexes de petites tailles telles que des vis, des ancres ou des plaques d’ostéosynthèse. Le bioverre permet au matériau de se lier facilement à
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10

Gwinner, Fernanda Pelógia Camargo [UNESP]. "Influência da adição de bioactive glass na liberação de íons do cimento de ionômero de vidro modificado por resina." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/105480.

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Made available in DSpace on 2014-06-11T19:35:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-06-18Bitstream added on 2014-06-13T20:25:44Z : No. of bitstreams: 1 gwinner_fpc_dr_sjc.pdf: 429388 bytes, checksum: 8f66379f177aa22a57995cbad67ae92f (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Esse estudo in vitro avaliou o efeito da adição de diferentes concentrações e composições de bioactive glass (BAG) ao cimento de ionômero de vidro modificado por resina (CIVMR) (Fuji II LC) na liberação de íons Ca2+ e PO4 3- após a imersão em simulador de fluido cor
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11

San, Miguel Riva Blanca. "Enhanced bone regeneration by means of bioresorbable and bioactive materials /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17175.

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12

Khan, Md Arif. "NANOHARVESTING AND DELIVERY OF BIOACTIVE MATERIALS USING ENGINEERED SILICA NANOPARTICLES." UKnowledge, 2019. https://uknowledge.uky.edu/cme_etds/110.

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Mesoporous silica nanoparticles (MSNPs) possess large surface areas and ample pore space that can be readily modified with specific functional groups for targeted binding of bioactive materials to be transported through cellular barriers. Engineered silica nanoparticles (ESNP) have been used extensively to deliver bio-active materials to target intracellular sites, including as non-viral vectors for nucleic acid (DNA/RNA) delivery such as for siRNA induced interference. The reverse process guided by the same principles is called “nanoharvesting”, where valuable biomolecules are carried out and
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13

Lázaro, Gilderman Silva. "Efeito individual e combinado de óxidos do tipo MO (M=Sr, Zn, Mg) sobre as propriedades térmicas e reatividade de superfície de biovidros." Pós-Graduação em Ciência e Engenharia de Materiais, 2014. https://ri.ufs.br/handle/riufs/3545.

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The aim of this study was to evaluate the effect of replacing CaO by ZnO, MgO and SrO on a standard bioglass composition SiO2.CaO.Na2O.P2O5 on their thermal behavior and surface reactivity. The analyses showed that the substitution did not directly affect the events of mass loss. However, the reduction in Tg, was linear with oxide concentration. MgO strongly contributed to Tg reduction while SrO and ZnO had similar behavior. The simultaneous addition of all three oxides showed an antagonistic effect on the Tg. The crystallization temperature did not vary linearly with increasing concentration
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14

Pavlov, Anton M. "Multilayer microcapsules for delivery, control and triggered release of bioactive compounds." Thesis, Queen Mary, University of London, 2012. http://qmro.qmul.ac.uk/xmlui/handle/123456789/2961.

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Developing of targeted drug delivery systems is currently a very important topic, which can be easily judged by a great number of papers published every year. Materials science proposes, among others, microcapsules as one of the possible solutions to the problem. Known for more than a decade by know, microcapsules, their properties, methods of encapsulation, release, control where under thorough investigation by several scientific groups in the world. Despite the fact that many factors were already studied, application of this system to drug delivery provides an enormous amount of work yet to
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Gwinner, Fernanda Pelógia Camargo. "Influência da adição de bioactive glass na liberação de íons do cimento de ionômero de vidro modificado por resina /." São José dos Campos : [s.n.], 2009. http://hdl.handle.net/11449/105480.

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Orientador: Alvaro Della Bona<br>Banca: Marco Antonio Bottino<br>Banca: Tarcisio José de Arruda Paes Júnior<br>Banca: Simonides Consani<br>Banca: Lourenço Correr Sobrinho<br>Resumo: Esse estudo in vitro avaliou o efeito da adição de diferentes concentrações e composições de bioactive glass (BAG) ao cimento de ionômero de vidro modificado por resina (CIVMR) (Fuji II LC) na liberação de íons Ca2+ e PO4 3- após a imersão em simulador de fluido corpóreo (SFC), comparando com o grupo controle, sem BAG. Foram utilizados 3 tipos de BAG: BAG65 (65mol% SiO2, 31mol% CaO, 4mol% P2O5), BAG75 (75mol% SiO2,
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16

Liu, Ya, and 刘亚. "Developing bioactive and biodegradable composites for bone tissue repair." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B4150835X.

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Liu, Ya. "Developing bioactive and biodegradable composites for bone tissue repair." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B4150835X.

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18

Lau, Yeuk Tin. "Bioavailability and bioactivity enhancement by nanomization /." View abstract or full-text, 2009. http://library.ust.hk/cgi/db/thesis.pl?BIEN%202009%20LAU.

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19

Heiati, Hashem. "Development and characterization of solid lipid nanoparticles for delivery of bioactive materials." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ38805.pdf.

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20

Allan, Iain Urquhart. "The formation and viability of oral bacterial biofilms on bioactive implant materials." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394274.

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21

Nishio, Ken. "The effects of bioactive materials on osteoblastic differentiation of bone marrow cells." Kyoto University, 2001. http://hdl.handle.net/2433/150524.

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22

Miyazaki, Toshiki. "Preparation of tantalum-or niobium-based bioactive materials by chemical surface modification." 京都大学 (Kyoto University), 2002. http://hdl.handle.net/2433/149430.

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23

Bell, Bryan Frederick Jr. "Functionally graded, multilayer diamondlike carbon-hydroxyapatite nanocomposite coatings for orthopedic implants." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/7962.

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24

Vandiver, Jennifer M. (Jennifer McKeehan). "Nanoscale influences on bioactivity : ultrastructure and nanomechanics of model bioactive hydroxyapatite based biomaterials." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/37569.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2006.<br>Includes bibliographical references.<br>There is a significant need for improved synthetic materials as orthopedic implants to replace human bone lost and damaged due to disease or injury. Certain ceramics, such as hydroxyapatite (HA), have the special property of being bioactive, meaning that an interfacial bond between the implant and the surrounding tissue forms, leading to good fixation. Bioactive ceramics are being investigated in a wide variety of forms for use in different bone i
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25

Wendt, Natalja [Verfasser], and Peter [Akademischer Betreuer] Behrens. "Bioactive silica and titania coatings on implant materials / Natalja Wendt ; Betreuer: Peter Behrens." Hannover : Gottfried Wilhelm Leibniz Universität Hannover, 2018. http://d-nb.info/1172414297/34.

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26

Khan, Abdul Samad. "A novel bioactive nano-composite : synthesis and characterisation with potential use as dental restorative material." Thesis, Queen Mary, University of London, 2009. http://qmro.qmul.ac.uk/xmlui/handle/123456789/441.

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It is desirable for a dental restorative material to have bioactive and bonding properties. This study focuses on the synthesis of a covalently-linked polyurethane/nanohydroxyapatite (PU/nHA) composite and evaluates its chemical, physical, thermal and biochemical characteristics. nHA powder was produced from the sol-gel and novel composite material was chemically prepared by utilising solvent polymerisation. The resulting composites were analysed by chemical, thermal, and mechanical characterisations and electrospun to form fibre mats. The composites were hydrolytically degraded in deionised w
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27

Bell, Bryan Frederick. "Functionally graded, multilayer diamondlike carbon-hydroxyapatite nanocomposite coatings for orthopedic implants." Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-06072004-131058/unrestricted/bell%5Fbryan%5Ff%5F200405%5Fms.pdf.

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28

Nzambe, Ta Keki Jean Kerim. "Elaboration de matériaux bioactifs à partir de fibres lignocellulosiques." Thesis, Limoges, 2015. http://www.theses.fr/2015LIMO0133/document.

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Les contaminations des surfaces constituent un problème majeur de santé public rencontré dans plusieurs secteurs tels que les milieux hospitaliers et l’industrie alimentaire. Cette contamination consiste en l’adhésion de bactéries pathogènes ou opportunistes qui peuvent former des biofilms. Ces biofilms sont potentiellement des sources de développement et de prolifération des bactéries. Une voie efficace de lutte contre la contamination microbienne est l’élaboration de surfaces bactéricides visant à empêcher ou diminuer l’adhésion bactérienne. Basé sur le savoir-faire du laboratoire de Chimie
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LOTY, CHRISTINE. "Stimulation in vitro de la chondrogenese et de l'osteogenese par des materiaux bioactifs." Paris 7, 2000. http://www.theses.fr/2000PA07GA03.

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Barroca, Natália Braz. "Scaffolds à base de polímeros piezoeléctricos para regeneração óssea." Master's thesis, Universidade de Aveiro, 2008. http://hdl.handle.net/10773/2284.

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Mestrado em Engenharia Biométrica - Biomateriais<br>Um dos grandes desafios no campo da engenharia de tecidos é o desenvolvimento de estruturas porosas tridimensionais (scaffolds) que permitam a adesão, a proliferação e a produção de matriz extracelular à taxa a que decorre a degradação do scaffold. Os scaffolds compósitos de matriz polimérica com enchimentos cerâmicos bioactivos têm sido objecto de investigação recente, pois combinam as vantagens destes dois tipos de materiais e mimetizam razoavelmente o osso, que é um compósito natural. Neste trabalho, foram preparados scaffolds compósitos u
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Bernardos, Bau Andrea. "Desarrollo y síntesis de materiales híbridos, para la liberación controlada de moléculas bioactivas." Doctoral thesis, Editorial Universitat Politècnica de València, 2013. http://hdl.handle.net/10251/27151.

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En esta tesis se han desarrollado diferentes dispositivos de liberación controlada, utilizando materiales híbridos, y su aplicación como puerta nanoscópica molecular. Se describe en primer lugar, un método de liberación controlada para la vitamina B2 o riboflavina (vitamina hidrosoluble necesaria para el metabolismo de los hidratos de carbono, grasas y especialmente en el metabolismo de las proteínas que participan en el transporte de oxígeno) a través del uso de puertas nanoscópicas moleculares preparadas mediante el anclaje de agrupaciones poliaminicas en la superficie externa de los poros
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Ross, Ortiz Carolina Paz. "Elaboración de un compósito bioactivo y biocompatible a base de biovidrio 45S5 y óxido de grafeno." Tesis, Universidad de Chile, 2018. http://repositorio.uchile.cl/handle/2250/159293.

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Ingeniera Civil Química. Ingeniera Civil en Biotecnología<br>El continuo y creciente envejecimiento de la población conlleva a una mayor incidencia de enfermedades degenerativas óseas. Para su reparación se necesitan implantes que en un futuro no darán abasto para cubrir estas necesidades. Así, se hacen necesarias nuevas alternativas de reemplazo de injerto como los biomateriales. Entre ellos, el biovidrio 45S5 (BV) ha mostrado excelentes propiedades de biocompatibilidad y biodegradabilidad, mientras que el óxido de grafeno (GO) de proliferación y diferenciación celular. Es así que, se propon
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Fu, Qiang. "Freeze casting of bioactive glass and ceramic scaffolds for bone tissue engineering." Diss., Rolla, Mo. : Missouri University of Science and Technology, 2009. http://scholarsmine.mst.edu/thesis/pdf/Fu_09007dcc806b51af.pdf.

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Thesis (Ph. D.)--Missouri University of Science and Technology, 2009.<br>Vita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed April 7, 2010) Includes bibliographical references.
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Ohlhaver, Christopher M. "Use of Surface Enhanced Raman Spectroscopy for the Detection of Bioactive Lipids." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5551.

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The detection and analysis of lipids in biological matrices for clinical applications poses many challenges, but rapid and reliable detection will prove invaluable for clinical diagnosis. Herein, we report the application of drop-casted Ag nanoplatelets as surface enhanced Raman scattering (SERS) substrates for qualitative detection of 20-hydroxyeicosatetraenoic acid (20-HETE), which is a potential biomarker for diagnosis of hypertensive disorders. Biomarker peaks of 20-HETE can be reliably detected and differentiated from those of the structurally similar lipids (arachidonic acid, eicosapent
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Winger, Theodore Medard. "Synthesis and characterization of supported bioactive phospholipid membranes : model substrates for biosurface engineering." Diss., Georgia Institute of Technology, 1997. http://hdl.handle.net/1853/9504.

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Modjinou, Tina. "Valorisation de la biomasse pour l'élaboration de matériaux bioactifs sous irradiation." Thesis, Paris Est, 2017. http://www.theses.fr/2017PESC1152/document.

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La valorisation des dérivés phénoliques et terpéniques issus de la biomasse s’insère parfaitement dans le défi actuel de nos sociétés qui pousse la chimie traditionnelle à évoluer vers une chimie durable. De par leur nature insaturée, les terpènes se montrent particulièrement intéressants pour synthétiser de nouveaux matériaux par réaction de chimie thiol-ène. Parallèlement, les dérivés phénoliques peuvent être facilement modifiés en synthons insaturés, susceptibles de réagir dans ces mêmes réactions. Ainsi, une large gamme de matériaux à base de linalol et d’eugénol a été élaborée sous irradi
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Candarlioglu, Lutfiye Pelin. "Biological characterization of strontium substituted bioactive glass as a new bone graft material." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/39385.

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Almeida, José Carlos Martins de. "Hybrid materials for biomedical applications." Doctoral thesis, Universidade de Aveiro, 2016. http://hdl.handle.net/10773/15973.

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Doutoramento em Ciência e Engenharia de Materiais<br>The increased longevity of humans and the demand for a better quality of life have led to a continuous search for new implant materials. Scientific development coupled with a growing multidisciplinarity between materials science and life sciences has given rise to new approaches such as regenerative medicine and tissue engineering. The search for a material with mechanical properties close to those of human bone produced a new family of hybrid materials that take advantage of the synergy between inorganic silica (SiO4) domains, based on sol-
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Silva, Bianca Catarina Guimarães da. "Fabrico de scaffolds porosos de vidro bioativo para regeneração óssea." Master's thesis, Universidade de Aveiro, 2015. http://hdl.handle.net/10773/16970.

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Mestrado em Materiais e Dispositivos Biomédicos<br>A Engenharia de Tecidos é um domínio multidisciplinar com o objetivo de desenvolver substitutos biológicos para a regeneração, reparação ou restauração de funções de órgãos ou tecidos. Os scaffolds são materiais porosos tridimensionais que servem de matrizes para a adesão e proliferação das células, bem como para a produção de matriz extracelular, idealmente, à taxa a que decorre a degradação do scaffold. A conceção de estruturas adequadas para suportar o restauro ou melhorar a função de tecidos é um dos maiores desafios da Engenharia de Tecid
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Cañas, Recacha Eugeni. "Deposición de recubrimientos bioactivos mediante proyección térmica por plasma a partir de distintos materiales de aporte." Doctoral thesis, Universitat Jaume I, 2021. http://dx.doi.org/10.6035/14107.2021.253501.

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Desde hace varias décadas, se implantan prótesis recubiertas de hidroxiapatita mediante proyección térmica por plasma. Se trata de un material cerámico bioactivo de composición similar a la fase mineral del hueso humano. Sin embargo, recientemente se ha comenzado a estudiar los vidrios bioactivos como sustitutos de la hidroxiapatita para tal fin puesto que, aunque ambos son biocompatibles y poseen propiedades mecánicas similares, estos vidrios presentan mayor bioactividad. Por ello, esta tesis se enfoca en la deposición de recubrimientos a partir de vidrios bioactivos mediante proyección térmi
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Kapoor, Saurabh. "Alkali-free bioactive glasses for bone regeneration." Doctoral thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/13951.

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Doutoramento em Ciência e Engenharia dos Materiais<br>Bioactive glasses and glass-ceramics are a class of third generation biomaterials which elicit a special response on their surface when in contact with biological fluids, leading to strong bonding to living tissues. The purpose of the present study was to develop diopside based alkali-free bioactive glasses in order to achieve good sintering behaviour, high bioactivity, and a dissolution/ degradation rates compatible with the target applications in bone regeneration and tissue engineering. Another aim was to understand the structure-p
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Martins, Carolina Scanavez. "Expressão das proteínas citoesqueléticas actina e tubulina em células osteogênicas cultivadas sobre vidro e vitrocerâmica bioativos." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/58/58132/tde-14082012-083511/.

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A implantação de materiais vítreos e vitrocerâmicos bioativos representa estratégia terapêutica importante para se promover a formação de matriz extracelular mineralizada em defeitos ósseos críticos. Quando expostos a fluidos biológicos, estes biomateriais sofrem alterações químicas e topográficas de superfície que afetam as interações de células com sua superfície, reduzindo o espraiamento celular e alterando o padrão de marcação de proteínas do citoesqueleto. O objetivo deste estudo foi avaliar se as alterações no padrão de marcação para as proteínas citoesqueléticas actina e tubulina observ
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Nakaji(Hirabayashi), Tadashi. "Design of Bioactive Materials with Chimeric Proteins for Controlling Proliferation and Differentiation of Neural Stem Cells." 京都大学 (Kyoto University), 2009. http://hdl.handle.net/2433/124507.

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Tsigkou, Olga. "Effects of bioactive resorbable materials on human primary osteoblasts : investigating the role of Bioglass on osteosis." Thesis, Imperial College London, 2006. http://hdl.handle.net/10044/1/11223.

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Hugoni, Ludivine. "Development of fibronectin coatings on polymeric materials : a study of protein-surface interactions." Master's thesis, Université Laval, 2016. http://hdl.handle.net/20.500.11794/27319.

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L’adsorption de protéines adhésives telles que la fibronectine (Fn) à la surface d’un dispositif médical suivant son introduction dans le corps joue un rôle critique dans la réponse biologique. Afin de moduler cette réponse, la création de revêtements bioactifs à la surface des matériaux représente une stratégie à adopter. Dans ce contexte, ce projet de recherche vise à développer des revêtements capables de promouvoir des interactions cellulaires spécifiques. Ainsi, des revêtements de fibronectine ont été développés à la surface de polymères présentant un potentiel pour être utilisés comme bi
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Bchellaoui, Nizar. "Elaboration par voie microfluidique de microcapsules monodisperses de verre de silice à caractéristiques morphologiques et optiques contrôlées." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLN062/document.

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Les nanosciences représentent, actuellement, un domaine de recherche en pleine expansion grâce aux nombreuses applications auxquelles elles peuvent être associées, et en particulier à la course à la miniaturisation des systèmes. De plus, il a rapidement été montré que les propriétés physico-chimiques des matériaux à l’échelle nanométrique sont modifiées parfois de manière drastique, à cause par exemple des effets quantiques apparaissant à des tailles aussi petites, mais aussi en raison des effets de confinement. Le confinement de molécules ou de particules à l’échelle nanoscopique nécessite do
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47

Amaral, Margarida Isabel dos Santos. "Sinterabilidade e comportamento biológico de compósitos bioactivos de Matriz de Nitreto de Silício." Master's thesis, Universidade de Aveiro, 2001. http://hdl.handle.net/10773/4488.

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Mestrado em Engenharia dos Materiais<br>O principal objectivo da presente dissertação de mestrado é a optimização da produção de compósitos de nitreto de silício (Si3N4)-biovidro e avaliação do respectivo desempenho mecânico e biológico tendo em vista a sua utilização em aplicações biomédicas. Este biomaterial é composto por 70% e 30% em peso de Si3N4 e biovidro, respectivamente, combinando vantajosamente as propriedades de ambos os constituintes. O Si3N4 é um material que apresenta uma excelente conjugação de propriedades mecânicas para um cerâmico e funciona como matriz estrutural de
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48

Canceill, Thibault. "Développement d'un biomatériau naturel, bioactif, dérivé du sang pour la régénération tissulaire." Thesis, Toulouse 3, 2021. http://www.theses.fr/2021TOU30024.

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Le Lysat Plaquettaire (LP) est un produit dérivé du sang naturellement riche en facteurs de croissance comme le VEGF, le PDGF ou encore le TGF-ß1. Cela lui confère la capacité de stimuler les cellules de l'hôte pour promouvoir la cicatrisation voire même la régénération des tissus lésés. Associé à du chlorure de calcium et de l'acide tranexamique, le LP peut former un hydrogel composé d'un réseau tridimensionnel de fibrine, mimant une matrice extracellulaire naturelle riche en facteurs de croissance dans laquelle les cellules trouvent tous les éléments nécessaires à leur développement. Les cha
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Ho, Yee Hsien. "In Vitro Behavior of AZ31B Mg-Hydroxyapatite Metallic Matrix Composite Surface Fabricated via Friction Stir Processing." Thesis, University of North Texas, 2016. https://digital.library.unt.edu/ark:/67531/metadc862762/.

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Magnesium and its alloys have been considered for load-bearing implant materials due to their similar mechanical properties to the natural bone, excellent biocompatibility, good bioactivity, and biodegradation. Nevertheless, the uncontrollable corrosion rate in biological environment restrains their application. Hydroxyapatite (HA, Ca10(PO4)6(OH)2) is a widely used bio-ceramic which has bone-like mineral structure for bone fixation. Poor fracture toughness of HA makes it not suitable for load-bearing application as a bulk. Thus, HA is introduced into metallic surface in various forms for impro
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Xiang, Ye. "Computational Studies on Structures and Ionic Diffusion of Bioactive Glasses." Thesis, University of North Texas, 2014. https://digital.library.unt.edu/ark:/67531/metadc700054/.

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Bioactive glasses are a class of synthetic inorganic material that have wide orthopedics, dentistry, tissue engineering and other biomedical applications. The origin of the bioactivity is closely related to the atomic structures of these novel glass materials, which otherwise lack long range order and defies any direct experimental measurements due to their amorphous nature. The structure of bioactive glasses is thus essential for the understanding of bioactive behaviors and eventually rational design of glass compositions. In this dissertation, molecular dynamics (MD) and reverse monte carlo
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