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Dissertations / Theses on the topic 'Mathematical modeling. eng'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Campos, Celso Ribeiro. "A educação estatística : uma investigação acerca dos aspectos relevantes à didática da estatística em cursos de graduação /." Rio Claro : [s.n.], 2007. http://hdl.handle.net/11449/102161.

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Orientador: Maria Lúcia Lorenzetti Wodewotzki<br>Banca: Sandra Maria Pinto Magina<br>Banca: Cileda de Queiroz e Silva Coutinho<br>Banca: Antonio Carlos Simões Pião<br>Banca: Otávio Roberto Jacobini<br>Resumo: Os objetivos desse trabalho são o estudo teórico sobre os fundamentos da didática da Educação Estatística e sua integração com a Educação Crítica e com a Modelagem Matemática e aplicação dessa integração no microcosmo da sala de aula, com o desenvolvimento e a execução de projetos pedagógicos voltados para esse fim. Sobre os fundamentos teóricos da didática da Estatística, observamos que

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2

Herminio, Maria Helena Garcia Barbosa. "O processo de escolha dos temas dos projetos de modelagem matemática /." Rio Claro : [s.n.], 2009. http://hdl.handle.net/11449/91074.

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Orientador: Marcelo de Carvalho Borba<br>Banca: Otávio Roberto Jacobini<br>Banca: Arlete de Jesus Brito<br>Resumo: Esta pesquisa buscou compreender quais são as dimensões envolvidas no processo de escolha dos temas dos projetos de Modelagem Matemática, quando os alunos são os responsáveis por essa tomada de decisão. O estudo foi desenvolvido com alunos do primeiro ano do curso de Ciências Biológicas da Unesp, campus de Rio Claro, na disciplina Matemática Aplicada, onde uma das vertentes da disciplina era a Modelagem Matemática. Fizemos uso da metodologia de pesquisa qualitativa utilizando proc

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3

Diniz, Leandro do Nascimento. "O papel das tecnologias da informação e comunicação nos projetos de modelagem matemática /." Rio Claro : [s.n.], 2007. http://hdl.handle.net/11449/91079.

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Orientador: Marcelo de Carvalho Borba<br>Banca: Jonei Cerqueira Barbosa<br>Banca: Otávio Roberto Jacobini<br>Resumo: Nesta pesquisa, investiguei como os alunos utilizam as Tecnologias da Informação e Comunicação (TIC) nos Projetos de Modelagem Matemática. A pesquisa foi desenvolvida com alunos do primeiro ano do curso de Ciências Biológicas da Unesp, campus de Rio Claro, na disciplina Matemática Aplicada. O professor convidou os alunos para que, reunidos em grupos, investigassem um tema qualquer do cotidiano, escolhido por eles. Os dados foram coletados por meio da observação de aulas da disci

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Sanches, Rosângela Peregrina. "Epidemiologia de doenças infecciosas : cólera e doença do caranguejo letárgico /." Botucatu : [s.n.], 2010. http://hdl.handle.net/11449/87915.

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Orientador: Cláudia Pio Ferreira<br>Banca: Eduardo Massad<br>Banca: Helenice de Oliveira Florentino Silva<br>Resumo: Os modelos epidemiológicos tem por objetivo reproduzir a dinâmica espacial e/ou temporal de doenças infecciosas, e propor possíveis estratégias de controle. Estes modelos auxiliam a compreensão do comportamento das doenças em relação à vários aspectos, como mecanismos de transmissão, sazonalidade (dependência dos parâmetros do modelo em relação a temperatura, umidade, etc.) e disseminação da doença (Yang, 2001). Para isso são levantadas hipóteses matemáticas, baseadas em conheci

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Sartori, Junior Sergio. "Modelagem matemática e análise dinâmica da torre de um pulverizador de pomares /." Bauru : [s.n.], 2008. http://hdl.handle.net/11449/97035.

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Orientador: José Manoel Balthazar<br>Banca: Bento Rodrigues de Ponte Junior<br>Banca: Hans Ingo Weber<br>Resumo: Na área agrícola, um tipo de equipamento utilizado para a pulverização de pomares, consiste essencialmente de uma estrutura vertical com ventiladores dotados de bicos de pulverização, montados sobre um veículo que trafega entre as plantas. Em uma construção mais simples esta estrutura vertical é montada na parte traseira de um trator agrícola. Em uma construção mais complexa, esta estrutura vertical é montada sobre uma carreta ou trailer, que pode ter ou não suspensão. Em algumas si

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6

Guelfi, Rangel. "Análise da relação entre o faturamento do consumo de energia elétrica e demanda de potência ativa e reativa utilizando hiperbolóides de carga e potência /." Ilha Solteira : [s.n.], 2007. http://hdl.handle.net/11449/87214.

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Resumo: No presente trabalho é apresentado um método para o cálculo de volumes determinados por K-Hiperbolóides de Carga e Potência, de modo a reduzir os gastos de empresas consideradas, em relação ao fator de potência. A redução de gastos é obtida alterando-se o valor máximo do fator potência que se pretende chegar, do fator de potência ideal "1", para o fator de potência de referência "0,92", ou mantendo-o quando já estiver acima de 0,92. Quando o fator de potência é maior ou igual a 0,92 ele já está eficiente, assim, não há necessidade de se chegar ao fator de potência ideal. É realizada um

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7

Sampaio, Luana Oliveira. "Educação estatística crítica : uma possibilidade? /." Rio Claro : [s.n.], 2010. http://hdl.handle.net/11449/91123.

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Orientador: Maria Lucia Lorenzetti Wodewotzki<br>Banca: Ole Skovsmose<br>Banca: Denise Helena Lombardo Ferreira<br>Resumo: Este trabalho discorre sobre uma experiência com alunos de uma disciplina de Estatística para Administração. Com os quais realizamos, extraclasse, trabalhos via Modelagem Matemática a distância: um ambiente virtual de aprendizagem, onde os alunos foram convidados a investigar a realidade por meio da Estatística. Deste ambiente emergiu o termo ciberespaço de interação: todo encontro online com o objetivo de discutir e encaminhar atividades de Modelagem. Nesta pesquisa, o ob

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Jacobini, Otávio Roberto. "A Modelagem matemática como instrumento de ação política na sala de aula /." Rio Claro : [s.n.], 2004. http://hdl.handle.net/11449/102078.

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Orientador: Maria Lúcia Lorenzetti Wodewotzki<br>Banca: Marcelo de Carvalho Borba<br>Banca: Marcus Vinicius Maltempi<br>Banca: Ole Skovsmose<br>Banca: Alexandrina Monteiro<br>Resumo: Com esta pesquisa busquei analisar as possibilidades de crescimento político dos estudantes, quando a modelagem matemática é adotada como estratégia de ensino-aprendizagem. Considero essas possibilidades como reflexões que se identificam com questionamentos, críticas, ações e transformações. Ao inserir este estudo no contexto da Educação Matemática Crítica baseei minha pesquisa bibliográfica em autores que se iden

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Muthukumaran, Arun. "Foam-mat freeze drying of egg white and mathematical modeling." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18301.

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Eggs are a rich source of high-quality proteins as they contain all amino acids necessary for the human body. They also contain all vitamins (except for vitamin C) and many essential minerals. Eggs mainly consist of egg white (albumen) and egg yolk. Egg white is mainly made up of proteins and has excellent foaming properties; it is widely used in the baking and confectionary industries (e.g., cake mixtures, meringue). Dehydration is widely used for the preservation of egg. Dehydrated egg products usually have a shelf life of one year under refrigeration. Spray drying and pan drying are widely

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Pritchard, Adaleigh Elizabeth. "Modeling End-to-End Annealing of Intermediate Filaments." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1397743583.

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Andrade, Mirian Maria. "Ensino e aprendizagem de estatística por meio da modelagem matemática : uma investigação com o ensino médio /." Rio Claro : [s.n.], 2008. http://hdl.handle.net/11449/91104.

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Orientador: Maria Lúcia Lorenzetti Wodewotzki<br>Banca: Otávio Roberto Jacobini<br>Banca: Ole Skovsmose<br>Resumo: Esta pesquisa visa investigar quais as implicações que o ambiente da Modelagem Matemática pode oferecer para o processo de ensino e aprendizagem da Estatística no âmbito do ensino médio. Assim, os objetivos da pesquisa se configuram como: propor o estudo de Estatística por meio da Modelagem Matemática no contexto do ensino médio e assim investigar e discutir as implicações que tal ambiente de aprendizagem pode oferecer para o ensino e a aprendizagem da Estatística; favorecer e val

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Peng, Lu. "Multiscale mathematical modelling of cancer invasion." Thesis, University of Dundee, 2015. https://discovery.dundee.ac.uk/en/studentTheses/c0aec459-7953-4172-b1f9-5ad029aae9df.

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Invasion of the surrounding tissue is one of the hallmarks of cancer. Solid tumours have a reciprocal relationship with the surrounding microenvironment, a complex tissue composed of extracellular matrix and other multiple distinct cell types. Prote- olytic degradation and remodelling of the extracellular matrix is essential for cancer cells to be able to invade. Important matrix degrading enzymes include the matrix metalloproteases (MMP) and the urokinase plasminogen activator (uPA). This thesis has investigated the complex process of cancer growth and spread that occur across several differe

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Li, Laoshen. "Mathematical modelling of mechanisms for biofilm expansion." Thesis, University of Dundee, 2014. https://discovery.dundee.ac.uk/en/studentTheses/c86dd46a-acf9-48a1-9e4f-11bcca0b778f.

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Biofilms are multi-cellular communities of microorganisms attached to surfaces. It has been estimated that about 99% of all bacteria exist in biofilm. Thus to understand the critical role bacteria play in natural and man-made ecosystems, requires a better knowledge of these multi-cellular communities. Biofilms are complex structures comprising cells embedded in a sticky material composed of extracellular polymeric substances (EPS) produced by the cells themselves. The physical structure of the biofilm has been shown to be important to its evolutionary success. EPS is involved in maintaining st

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Tough, Iona Kirsten. "Mathematical modelling of the immune response to cancer." Thesis, University of Dundee, 2017. https://discovery.dundee.ac.uk/en/studentTheses/15b9aa4f-f2b3-44bc-90a6-31cfb6470b90.

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The immune system’s vitality and function is of the upmost importance in the human body. The ingenuity and performance of this defence mechanism also plays a role in the prevention of mutated, transformed cells becoming malig- nant tumours (cancers). More recently, the subject of cancer immunology has been concerned with examining the local effects the immune system has on a pre-angiogenic tumour site. A recent immunological review article - “The Three Es of Cancer Immunoediting” - discusses the way the immune system interacts with cancer cells: elimination, equilibrium, and escape. This bio-

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Wallace, Heather A. "Mathematical modelling of wrinkle formation in bacterial biofilms." Thesis, University of Dundee, 2016. https://discovery.dundee.ac.uk/en/studentTheses/5ecaa42d-7299-4d33-a245-45c7f535570a.

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Biofilms are matrix-producing communities of bacterial cells that adhere to surfaces and adopt a multicellular lifestyle. As the predominant life-form of bacteria (estimates suggest that 99% of all bacteria exist in biofilm communities), biofilms play a crucial role in the Earth’s ecosystems, where their existence is known to contribute both beneficial and detrimental effects. One of the defining characteristics of biofilms is heterogeneity in their structure. Indeed, it is commonly observed that biofilms of certain species of bacteria grown under certain conditions can display an unusual wrin

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Garcia-Hermosa, M. Isabel. "Morphodynamics of sand mounds in shallow flows." Thesis, University of Oxford, 2008. http://ora.ox.ac.uk/objects/uuid:c6ef38f8-d098-4ce5-b0f0-38e2ebe6caf5.

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Large-scale bed features are often encountered in coastal waters, and include sandbanks and spoil heaps. The morphodynamic development of such features involves complicated nonlinear interactions between the flow hydrodynamics, sediment transport, and bed profile. Numerical modelling of the morphodynamic evolution and migration of large-scale bed features is necessary in order to understand their long-term behaviour in response to changing environmental conditions. This thesis describes detailed measurements of the morphodynamics of sand mounds in unidirectional and oscillatory (tidal) flows,

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Ferreira, Denise Helena Lombardo. "O Tratamento de questões ambientais através da modelagem matemática : um trabalho com alunos do ensino fundamental e médio /." Rio Claro : [s.n.], 2003. http://hdl.handle.net/11449/102168.

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Resumo: Esta pesquisa tem como objetivo buscar compreender como ocorre a participação dos alunos, e quais elementos sociais e pedagógicos tornam-se presentes ao se abordar questões ambientais, na perspectiva do ensino-aprendizagem da Modelagem Matemática. A pesquisa foi desenvolvida numa abordagem qualitativa com alunos do Ensino Fundamental e Médio, ambas escolas públicas do município de Rio Claro, SP. A ação pedagógica, desenvolvida na perspectiva de Modelagem Matemática, envolveu os temas Água, Lixo, Energia Elétrica e Desmatamento, com a confecção de alguns modelos, dentre os quais, previs

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Ávila, Ricardo Pereira de. "Modelagem matemática da doença do caranguejo letárgico via ondas viajantes /." Botucatu : [s.n.], 2010. http://hdl.handle.net/11449/87917.

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Orientador: Paulo Fernando de Arruda Mancera<br>Banca: Cláudia Pio Ferreira<br>Banca: Norberto Anibal Maidana<br>Resumo: O caranguejo-uçá, Ucides cordatus, tem fundamental importância para os manguezais, seu ambiente natural, realizando a decomposição de matéria orgânica, e também sendo um importante biomonitor de áreas críticas. Sua comercialização é considerada a atividade econômica mais importante relacionada a manguezais, e essencial para o sustento das comunidades ribeirinhas. Desde 1997, têm sido observados eventos de mortandade das populações dessa espécie, com redução de até 85% das co

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Chen, Y. "Mathematical modelling of end-to-end packet delay in multi-hop wireless networks and their applications to QoS provisioning." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1415093/.

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This thesis addresses the mathematical modelling of end-to-end packet delay for Quality of Service (QoS) provisioning in multi-hop wireless networks. The multi-hop wireless technology increases capacity and coverage in a cost-effective way and it has been standardised in the Fourth-Generation (4G) standards. The effective capacity model approximates end-to-end delay performances, including Complementary Cumulative Density Function (CCDF) of delay, average delay and jitter. This model is first tested using Internet traffic trace from a real gigabit Ethernet gateway. The effective capacity model

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Suchatawat, Maturose. "Mathematical modelling of multiple pulsed laser percussion drilling." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/mathematical-modelling-of-multiple-pulsed-laser-percussion-drilling(61023a9c-3900-4cc0-9043-5a9b17435fbd).html.

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In laser percussion drilling, a series of laser pulses with specified energies and durations irradiate the workpiece surface to gradually heat, melt, and vaporise material until a hole with-required depth-and-diameter-is-achieved. Despite being the quickest technique for producing small diameter holes, laser percussion drilling regularly suffers from difficulties in controlling the hole quality such as hole circularity, hole taper and recast layer. Therefore, in order to produce holes to a specific requirement at minimum cost and time, it is crucial to fully understand the effects of each para

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Rennie, Christopher John. "Modeling the large-scale electrical activity of the brain." University of Sydney. Physics, 2001. http://hdl.handle.net/2123/816.

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Modeling of brain activity is often seen as requiring great computing power. However in the special case of modeling scalp EEG it is possible to adopt a continuum approximation for the cortex, and then to use the techniques of wave physics to describe its consequent large-scale dynamics. The model incorporates the following critical components: two classes of neurons (excitatory and inhibitory), the typical number and strength of connections between these two classes, the corresponding connections within the thalamus and between the thalamus and cortex, the time constants and basic physio

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Oliveira, Helena Gutierrez. "Dinâmica populacional de Zaprionus indianus (Gupta, 1970) (Diptera: Drosophilidae) sob condições experimentais /." Rio Claro : [s.n.], 2009. http://hdl.handle.net/11449/99514.

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Orientador: Cláudio José von Zuben<br>Banca: Wesley Augusto Conde Godoy<br>Banca: Marcos Aparecido Pizano<br>Resumo: Um dos principais fatores que afetam negativamente a produtividade da fruticultura no país é o ataque dos frutos por pragas agrícolas como as moscas-das-frutas. A espécie Zaprionus indianus (Gupta, 1970) (Diptera: Drosophilidae), recentemente introduzida no Brasil, vem causando crescente preocupação devido aos danos causados pela mesma na produção de frutos, especialmente o figo roxo (Ficus carica, Moraceae) e aos impactos nas comunidades nativas de drosofilídeos. Esta dissertaç

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Arshad, Haroon. "Mathematical modelling of pulmonary arterial smooth muscle cell subtypes." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/mathematical-modelling-of-pulmonaryarterial-smooth-muscle-cell-subtypes(c1110807-d94d-487c-90b8-8714d5e42d16).html.

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Alteration in the tone of pulmonary arteries may lead to disease such as pulmonary hypertension often associated with major cardiac complications. This dysfunction is partly in the pulmonary arterial smooth muscle cells (PASMCs) where the excitation-contraction coupling is modified by ion channel behaviour to increase the contractile force. Mathematical models of systemic smooth muscle cells (SMCs) that incorporate electrophysiological and chemomechanical mechanisms to understand the underlying cellular physiology have been successfully employed. Models of pulmonary arterial smooth muscle cell

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Goodfellow, Marc. "Spatio-temporal modelling and analysis of epileptiform EEG." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/spatiotemporal-modelling-and-analysis-of-epileptiform-eeg(0f76259a-1a58-44a9-b08b-1402c9b49896).html.

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In this thesis we investigate the mechanisms underlying the generation of abnormal EEG rhythms in epilepsy, which is a crucial step towards better treatment of this disorder in the future. To this end, macroscopic scale mathematical models of the interactions between neuronal populations are examined. In particular, the role of interactions between neural masses that are spatially distributed in cortical networks are explored. In addition, two other important aspects of the modelling process are addressed, namely the conversion of macroscopic model variables into EEG output and the comparison

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Rowley, William. "Mathematical modelling of novel metamaterials for noise reduction applications." Thesis, University of Manchester, 2018. https://www.research.manchester.ac.uk/portal/en/theses/mathematical-modelling-of-novel-metamaterials-for-noise-reduction-applications(7ce8e9fb-4c2c-4637-ac89-c156949f9a27).html.

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In this thesis we investigate acoustic metamaterials and how they can influence incident sound waves. Specifically we are interested in the mathematical technique of transformation acoustics and how several simple examples of metamaterials, devised via transformation acoustics, can be realised physically. We present a simple methodology for optimising microstructure consisting of rods with elliptical cross sections arranged on a rectangular array in order to best fit the material properties required by a desired transformation. We present in detail three such examples: a one dimensional scalin

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Mohd, Jaffar Mai. "Mathematical models of hyphal tip growth." Thesis, University of Dundee, 2012. https://discovery.dundee.ac.uk/en/studentTheses/140f9a81-12ca-4337-a311-2f82441f1ea6.

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Filamentous fungi are important in an enormous variety of ways to our life, with examples ranging from bioremediation, through the food and drinks industry to human health. These organisms can form huge networks stretching metres and even kilometres. However, their mode of growth is by the extension of individual hyphal tips only a few microns in diameter. Tip growth is mediated by the incorporation of new wall building materials at the soft apex. Just how this process is controlled (in fungi and in cell elongation in other organisms) has been the subject of intense study over many years and h

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Bianconi, André. "Descrição da resposta germinativa de cultivares de Phaseolus vulgaris L. (Fabaceae) à temperatura e ao potencial osmótico /." Rio Claro : [s.n.], 2009. http://hdl.handle.net/11449/87883.

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Orientador: Victor José Mendes Cardoso<br>Banca: Fábio Socolowski<br>Banca: Gustavo Habermann<br>Resumo: A germinação de sementes representa uma etapa crítica para a sobrevivência da maioria das fanerógamas. Composição de gases, temperatura e água são os principais fatores ambientais limitantes do processo de germinação. Entre esses, a temperatura e a água exibem maior grau de flutuação, tanto em escala temporal como espacial, no ambiente terrestre, funcionando como importantes sinalizadores ambientais para a semente. Os objetivos deste trabalho foram fornecer a caracterização básica dos padrõ

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Østerbø, Olav. "Mathematical modelling and analysis of communication networks: transient characteristics of traffic processes and models for end-to-end delay and delay-jitter." Doctoral thesis, Norwegian University of Science and Technology, Faculty of Information Technology, Mathematics and Electrical Engineering, 2003. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-6.

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<p>The first part of the thesis (Part I) is devoted to find methods to describe transient behaviour of traffic processes, where the main emphasis is put on the description and analysis of excess periods and excess volumes of quite general stochastic processes. By assuming that traffic changes on different time scales, the transient characteristics such as excess periods could be important measures to describe periods of congestion on a communication link and moreover, the corresponding excess volume will represent lost information during such periods. Although the results obtained are of rathe

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Kelly, John. "Mathematical modelling of cancer growth and development : adhesion, stem cells and structure." Thesis, University of Dundee, 2014. https://discovery.dundee.ac.uk/en/studentTheses/94ea4aba-556e-4b08-a62e-a5000ce8bfe3.

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This thesis has investigated some of the intricacies of the growth and development of a solid tumour. Mathematical models and biological experimentation were used to gain a better understanding of the dual roles that the proto-oncogenic protein β-catenin has in adhesion and transcription, as well as its involvement in the epithelial-mesenchymal transition. Emphasis was placed on the spatial location of β-catenin within cells to determine what function it is performing. A model was also created to explore the hypothesis that multiple forms of β-catenin exist within cells to perform separate fun

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Al-Tameemi, Mohannad Musa Eisa. "Mathematical modelling of the innate and adaptive immune response to solid tumours." Thesis, University of Dundee, 2011. https://discovery.dundee.ac.uk/en/studentTheses/a97a2d17-a3cd-4b51-9ba9-3fa82e74bfdb.

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In this thesis mathematical models describing the growth of a solid tumour in the presence of an immune response are presented. Specifically, attention is focused on the interactions between cytotoxic T-lymphocytes (CTLs) and tumour cells in a small, avascular multicellular tumour. At this stage of the disease the CTLs and the tumour cells are considered to be in a state of dynamic equilibrium or cancer dormancy. The precise biochemical and cellular mechanisms by which CTLs can control a cancer and keep it in a dormant state are still not completely understood from a biological and immunologic

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Deakin, Niall Ewan. "Mathematical modelling of cancer growth and spread : the role of matrix metalloproteinases." Thesis, University of Dundee, 2015. https://discovery.dundee.ac.uk/en/studentTheses/eadbebd1-2d73-4204-a22d-375344fb82b1.

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A mass of cells that grow without normal bounds is termed a benign tumour if it does not invade locally into the tissue and malignant when it invades into its surrounding tissue. Benign tumours are often harmless unless the pressure they exhibit onto the tissue surrounding it causes trouble to the functioning of the human body as is often the case in brain tumours (gliomas) or other vital organs of the body. It is malignant tumours that are deemed to be made up of cancer cells and it is this process of invasion that defines them and will be studied in this thesis. We do this by considering two

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Li, Qince. "Mathematical modelling of intracellular Ca2+ alternans in atrial and ventricular myocytes." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/mathematical-modelling-of-intracellular-ca2-alternans-in-atrial-and-ventricular-myocytes(54ff4d2a-f820-43b6-a572-4706850f28ec).html.

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During excitation-contraction coupling, Ca2+ transient induced by the depolarization of membrane potential is the trigger of mechanical contraction in cardiac myocytes, which is responsible for the pumping function of the heart. However, mechanisms underlying intracellular Ca2+ regulation and the coupling between Ca2+ transient and membrane potential are not completely understood. Abnormalities in intracellular Ca2+ regulation have been observed during heart failure and cardiac arrhythmias, such as intracellular Ca2+ alternans and T-tubule disorganization. In this project, intracellular Ca2+ d

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Choi, Cecilia. "A biophysically detailed mathematical model of a single late pregnant rat myometrial cell." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/a-biophysically-detailed-mathematical-model-of-a-single-late-pregnant-rat-myometrial-cell(6d2e1178-370a-4de1-b1fb-9660d1ecf799).html.

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While premature birth is still one of the major clinical problems worldwide, the exact physiological mechanisms underlying myometrium activity during pregnancy remain unclear. In this thesis, a novel biophysically detailed model was constructed using available experimental data to simulate chemical, electrical and mechanical activity in a late pregnant rat uterine myocycte. The developed model has been used to elucidate the ionic mechanism underlying myometrium functionality, providing better insights in the function of the uterus during pregnancy. The model consisted of 15 membrane currents,

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Obón, Estrada Eleonora. "Towards the recovery of rare earth elements from end-of-life products : hydrometallurgical routes and mathematical modelling of extraction systems." Doctoral thesis, Universitat Politècnica de Catalunya, 2019. http://hdl.handle.net/10803/669262.

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The rare earth elements (REEs) are essential ingredients for the development of modern industry and the transition to a more sustainable economy model. The unique physicochemical features of these elements, such as their magnetism and optical properties, are greatly expanding their application. They have become key elements for the manufacture of many ordinary consumer goods like hybrid cars, fluorescent lamps or electronic devices like mobile phones or tablets. The growing popularity of the rare earth elements derivatives is leading to an increase in the global demand and the price of these e

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Issa, Ragiab. "Experimental and mathematical modelling of metal ion-humic acid-silicate minerals interactions." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/experimental-and-mathematical-modelling-of-metal-ionhumic-acidsilicate-minerals-interactions(9d8c4096-d93a-4483-9790-4b65c6c2761e).html.

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A series of experiments were performed to study the sorption of humic acid and Eu3+ ion (at trace concentrations) on the minerals: montmorillonite, bentonite, diatomite and kaolinite in ternary systems. Humic acid and europium sorption were investigated as a function of humic acid concentration, ionic strength and pH. There was a strong uptake of humic acid on to the minerals with sorption increasing as humic acid concentration decreases. For montmorillonite, the uptake of discrete size fractions was also studied. It was found that the larger fractions were more strongly sorbing and were bette

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Méjasson, Patrick Gérard. "The mathematical modelling of electrical and thermal acceleration factors in VLSI conductors." Thesis, University of South Wales, 1996. https://pure.southwales.ac.uk/en/studentthesis/the-mathematical-modelling-of-electrical-and-thermal-acceleration-factors-in-vlsi-conductors(8937dbb9-05b8-4c2b-9010-ea63dfce690a).html.

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All semiconductor devices need electrical accessibility and thus some form of metal contact is required. This contact may be rectifying or ohmic, but the metals used in the chip construction are often unsuitable for making connections to the outside world. Invariably, layered metallizations are used to make the top metallic layer suitable for wire or tape ultrasonic-thermocompression bonding, usually involving aluminium or gold, or soldering using lead-tin alloys. When a semiconductor device is fabricated, it goes through a number of processes at the end of which it is metallized, passivated,

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Taylor, Peter. "Development of compartment models of epileptic spike-wave discharges." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/development-of-compartment-models-of-epileptic-spikewave-discharges(4f6f4ff6-f5cd-451f-a806-39590b58468e).html.

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Background: Despite the so-called "generalised" nature of many epileptic seizures, patient specific spatio-temporal properties have been shown using imaging data at the macroscopic level of the cortex. Previous computational models have failed to account for spatial heterogeneities at the scale of the entire cortex. Furthermore, one of they key benefits of developing a model is the ability to easily test stimulation protocols. Previous studies of generalised spike-wave (the hallmark of absence epilepsy) have abstracted away from this.METHODSIn this work we develop a set of models of epileptic

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Sanja, Ožvat. "One-dimensional mathematical modeling of flow and sediment transport in open channels using the lattice Boltzmann method." Phd thesis, Univerzitet u Novom Sadu, Fakultet tehničkih nauka u Novom Sadu, 2019. https://www.cris.uns.ac.rs/record.jsf?recordId=108606&source=NDLTD&language=en.

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<p>A one-dimensional unsteady open-channel flow with sediment transport lattice Boltzmann model is developed. The unsteady water flow model is based on the discharge-water level definition of the Saint-Venant equations. For the sediment active-layer concept is used. Geometrical transformations are applied to the governing equations, in order to transform non-uniform physical spatial grid, characteristic for natural geometry, into an uniform computational grid. New form of equilibrium distribution functions is derived. Bifurcation boudary conditions suitable with the lattice Bolcmann method are

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Andasari, Vivi. "Mathematical modelling of cancer cell invasion of tissue : discrete and continuum approaches to studying the central role of adhesion." Thesis, University of Dundee, 2011. https://discovery.dundee.ac.uk/en/studentTheses/9e8221c9-120b-4167-a870-dedade5fe90e.

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Adhesion, which includes cell-to-cell and cell-to-extracellular-matrix adhesion, plays an important role in cancer invasion and metastasis. After undergoing morphological changes malignant and invasive tumour cells, i.e., cancer cells, break away from the primary tumour by loss of cell-cell adhesion, degrade their basement membrane and migrate through the extracellular matrix by enhancement of cell-matrix adhesion. These processes require interactions and signalling cross-talks between proteins and cellular components facilitating the cell adhesion. Although such processes are very complex, th

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Steeneck, Daniel Waymouth. "Strategic Planning for the Reverse Supply Chain: Optimal End-of-Life Option, Product Design, and Pricing." Diss., Virginia Tech, 2014. http://hdl.handle.net/10919/51208.

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A company's decisions on how to manage its reverse supply chain (RSC) are important for both economic and environmental reasons. From a strategic standpoint, the key decision a manufacturer makes is whether or not to collect products at their end-of-life (EOL) (i.e., when their useful lives are over), and if so, how to recover value from the recovered products. We call this decision as the EOL option of a product, and it determines how the RSC is designed and managed overall. Many EOL options exist for a product such as resale, refurbishment, remanufacturing and part salvage. However, many

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Hill, Lydia. "Mathematical modelling of drug metabolism : using in silico techniques to investigate the cytochrome P450 enzyme system in hepatic reductase null mice." Thesis, University of Dundee, 2011. https://discovery.dundee.ac.uk/en/studentTheses/595884f7-742f-4559-b4cf-bbeccae06710.

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In silico modelling approaches are useful since they can minimise experimental costs and once set up can be used to replace animal testing for drugs. As such modelling techniques need to be developed to reduce dependence on animals for validation of pharmacological efficacy. The work within this thesis shows that computational methods can be used to model biological and medical problems effectively. The main aim of this thesis was to investigate Cytochrome P450 enzymes and their effect on drug metabolism through the use of the Hepatic Reductase Null(HRN) mouse. This was done through using a nu

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Milana, Pavić. "Mathematical modelling and analysis of polyatomic gases and mixtures in the context of kinetic theory of gases and fluid mechanics." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2014. https://www.cris.uns.ac.rs/record.jsf?recordId=87879&source=NDLTD&language=en.

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We construct two independent hierarchies of moment equations and we apply the maximum entropy principle for polyatomic gases. We formulate multivelocity and multitemperature model of Eulerian polyatomic gases starting from kinetic theory, that is compared in the neighborhood of global equilibrium state to the models based on extended thermodynamics. We analyze diffusion asymptotics of the Boltzmann equations for mixtures of monatomic gases.<br>Конструишу се две независне хијерархијеједначина момената и примењује се принципмаксимума ентропије за више

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Zaibidi, Nerda Zura. "Modelling human fairness in cooperative games : a goal programming approach." Thesis, University of Portsmouth, 2012. https://researchportal.port.ac.uk/portal/en/theses/modelling-human-fairness-in-cooperative-games(4c3d0987-0edc-45be-9c4b-b1114df6bb3e).html.

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The issues of rationality in human behavior and fairness in cooperation have gained interest in various economic studies. In many prescriptive models of games, rationality of human decision makers implicitly assumes exchange-ability. This means that real people are assumed to adopt the beliefs of a player as expressed in the game when placed in the shoes of that particular player. However, it is a well debated topic in the literature that this modeling assumption is not in accordance to what behavioral economists have observed in some games played with real human subjects. Even when assuming t

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Maddison, Louise. "Experimental and theoretical modelling of the MAPK pathway." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/experimental-and-theoretical-modelling-of-the-mapk-pathway(46773da5-85dd-4a3f-8e6c-e3559ba04f46).html.

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The MAPK pathway plays a crucial role in regulating cellular response to external stimuli. Binding of growth factors and other mitogenic signals to cell surface receptors initiates a phosphorylation-dependent relay of protein activation, resulting in altered transcription, ultimately regulating cell proliferation and differentiation. Signalling through this pathway is regulated by the coordinated function of specific protein kinases and protein phosphatases. As perturbation of this signalling system is often associated with diseases such as cancer, modelling is a useful means to help understan

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Fatah, Khwazbeen Saida. "Preference modelling approaches based on cumulative functions using simulation with applications." Thesis, University of South Wales, 2009. https://pure.southwales.ac.uk/en/studentthesis/preference-modelling-approaches-based-on-cumulative-functions-using-simulation-with-applications(60653456-e002-4a64-976a-8ae4e4fd4a7e).html.

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In decision making problems under uncertainty, Mean Variance Model (MVM) consistent with Expected Utility Theory (EUT) plays an important role in ranking preferences for various alternative options. Despite its wide use, this model is appropriate only when random variables representing the alternative options are normally distributed and the utility function to be maximized is quadratic; both are undesirable properties to be satisfied with actual applications. In this research, a novel methodology has been adopted in developing generalized models that can reduce the deficiency of the existing

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46

Gajjar, Parmesh. "Modelling size-segregation in dense granular flows." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/modelling-sizesegregation-in-dense-granular-flows(2378b72f-6fe6-4464-8d40-c77915d42444).html.

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Dense flows of grains are commonplace throughout natural and industrial environments, from snow-avalanches down the sides of mountains to flows of cereal down chutes as it is transported from one part of a factory to another. A ubiquitous feature in all of these flows is their ability to separate the different grain types when shaken, stirred, sheared or vibrated. Many flows are sheared through gravity and these flows are particularly efficient at segregating particles based on their size, with small particles percolating to the bottom of the flow and large particles collecting at the top. Wit

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Blair, James. "Modelling approaches for optimal liquidation under a limit-order book structure." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/modelling-approaches-for-optimal-liquidation-under-a-limitorder-book-structure(a7c23b2a-e2f8-4b4a-9865-8783d9837198).html.

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This thesis introduces a selection of models for optimal execution of financial assets at the tactical level. As opposed to optimal scheduling, which defines a trading schedule for the trader, this thesis investigates how the trader should interact with the order book. If a trader is aggressive he will execute his order using market orders, which will negatively feedback on his execution price through market impact. Alternatively, the models we focus on consider a passive trader who places limit orders into the limit-order book and waits for these orders to be filled by market orders from othe

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SANTOS, Marcos José Batista dos. "Modelos para avaliar o enriquecimento de selênio e vitamina E nos ovos de codornas japonesas e galinhas de postura." Universidade Federal Rural de Pernambuco, 2013. http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/6887.

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Submitted by (edna.saturno@ufrpe.br) on 2017-05-17T13:15:12Z No. of bitstreams: 1 Marcos Jose Batista dos Santos.pdf: 1103645 bytes, checksum: 5cac226fa34979ad4d0f47844cb516c6 (MD5)<br>Made available in DSpace on 2017-05-17T13:15:12Z (GMT). No. of bitstreams: 1 Marcos Jose Batista dos Santos.pdf: 1103645 bytes, checksum: 5cac226fa34979ad4d0f47844cb516c6 (MD5) Previous issue date: 2013-02-25<br>This thesis was proposed in order to: verify the performance and egg quality of japanese quails supplemented with selenium (Se) and vitamin E, investigate the performance, egg quality and modeling th

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Yang, Jie. "Prediction of combination efficacy in cancer therapy." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/prediction-of-combination-efficacy-in-cancer-therapy(1b49824b-9d5f-4d21-89d7-6160a810d05e).html.

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The cell cycle is an essential process in all living organisms that must be carefully regulated to ensure successful cell growth and division. Disregulation of the cell cycle is a key contributing factor towards the formation of cancerous cells. Understanding events at a cellular level is the first step towards comprehending how cancer manifests at an organismal level. Mathematical modelling can be used as a means of formalising and predicting the behaviour of the biological systems involved in cancer. In response, cell cycle models have been constructed to simulate and predict what happens to

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Blount, Kathryn. "Cancer systems biology : is the devil in the glycolytic detail?" Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/cancer-systems-biology-is-the-devil-in-the-glycolytic-detail(e0ad0c6b-76ec-4bba-8dd3-b583910f46f4).html.

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An approach to investigating cancer that has recently seen resurgence of interest is the “Warburg effect”. Otto Warburg originally described the altered metabolism of cancer cells and identified that they exhibit an increase in glucose uptake and lactate production. This up-regulation of glycolytic flux and glucose transport is now associated with 90% of cancers. In order to improve the overall understanding of the “Warburg effect” two forms of systems biology have been implemented - comparative in vitro analysis of kinetic activities and dynamic modelling. In this analysis, human breast cance

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