Academic literature on the topic 'Matka result'
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Journal articles on the topic "Matka result"
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Yang, Heping, Zong-Zhi Huang, Zhaohui Zeng, Changjin Chen, Robert R. Selby, and Shelly C. Lu. "Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer." American Journal of Physiology-Gastrointestinal and Liver Physiology 280, no. 2 (2001): G184—G190. http://dx.doi.org/10.1152/ajpgi.2001.280.2.g184.
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Methionine adenosyltransferase (MAT), an essential enzyme that catalyzes the formation of S-adenosylmethionine (SAM), is encoded by two genes, MAT1A (liver-specific) and MAT2A (non-liver-specific). We showed a switch from MAT1A to MAT2A expression in human liver cancer, which facilitates cancer cell growth. The present work examined the role of methylation in MAT2A transcriptional regulation. We found that the human MAT2A promoter is hypomethylated in hepatocellular carcinoma, in which the gene is upregulated transcriptionally, but hypermethylated in normal liver, in which the gene is minimally expressed. Luciferase activities driven by in vitro methylated MAT2A promoter constructs were 75–95% lower than activities driven by unmethylated constructs. SAM treatment of Hep G2 cells reduced MAT2A endogenous expression by 75%, hypermethylated the MAT2A promoter, and reduced luciferase activities driven by MAT2A promoter constructs by 65–75% while not affecting MAT1A's promoter activity. Treatment of adult rat and human hepatocytes with trichostatin A, an inhibitor of histone deacetylase, upregulated MAT2Aexpression by more than fourfold. Collectively, these results suggest that MAT2A expression is regulated by promoter methylation and histone acetylation.
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Chu, Pei-Yi, Hsing-Ju Wu, Shin-Mae Wang, Po-Ming Chen, Feng-Yao Tang, and En-Pei Isabel Chiang. "MAT2A Localization and Its Independently Prognostic Relevance in Breast Cancer Patients." International Journal of Molecular Sciences 22, no. 10 (2021): 5382. http://dx.doi.org/10.3390/ijms22105382.
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(1) Background: methionine cycle is not only essential for cancer cell proliferation but is also critical for metabolic reprogramming, a cancer hallmark. Hepatic and extrahepatic tissues methionine adenosyltransferases (MATs) are products of two genes, MAT1A and MAT2A that catalyze the formation of S-adenosylmethionine (SAM), the principal biological methyl donor. Glycine N-methyltransferase (GNMT) further utilizes SAM for sarcosine formation, thus it regulates the ratio of SAM:S-adenosylhomocysteine (SAH). (2) Methods: by analyzing the TCGA/GTEx datasets available within GEPIA2, we discovered that breast cancer patients with higher MAT2A had worse survival rate (p = 0.0057). Protein expression pattern of MAT1AA, MAT2A and GNMT were investigated in the tissue microarray in our own cohort (n = 252) by immunohistochemistry. MAT2A C/N expression ratio and cell invasion activity were further investigated in a panel of breast cancer cell lines. (3) Results: GNMT and MAT1A were detected in the cytoplasm, whereas MAT2A showed both cytoplasmic and nuclear immunoreactivity. Neither GNMT nor MAT1A protein expression was associated with patient survival rate in our cohort. Kaplan–Meier survival curves showed that a higher cytoplasmic/nuclear (C/N) MAT2A protein expression ratio correlated with poor overall survival (5 year survival rate: 93.7% vs. 83.3%, C/N ratio ≥ 1.0 vs. C/N ratio < 1.0, log-rank p = 0.004). Accordingly, a MAT2A C/N expression ratio ≥ 1.0 was determined as an independent risk factor by Cox regression analysis (hazard ratio = 2.771, p = 0.018, n = 252). In vitro studies found that breast cancer cell lines with a higher MAT2A C/N ratio were more invasive. (4) Conclusions: the subcellular localization of MAT2A may affect its functions, and elevated MAT2A C/N ratio in breast cancer cells is associated with increased invasiveness. MAT2A C/N expression ratio determined by IHC staining could serve as a novel independent prognostic marker for breast cancer.
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Shafqat, Naeem, Joao R. C. Muniz, Ewa S. Pilka, et al. "Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits." Biochemical Journal 452, no. 1 (2013): 27–36. http://dx.doi.org/10.1042/bj20121580.
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MAT (methionine adenosyltransferase) utilizes L-methionine and ATP to form SAM (S-adenosylmethionine), the principal methyl donor in biological methylation. Mammals encode a liver-specific isoenzyme, MAT1A, that is genetically linked with an inborn metabolic disorder of hypermethioninaemia, as well as a ubiquitously expressed isoenzyme, MAT2A, whose enzymatic activity is regulated by an associated subunit MAT2B. To understand the molecular mechanism of MAT functions and interactions, we have crystallized the ligand-bound complexes of human MAT1A, MAT2A and MAT2B. The structures of MAT1A and MAT2A in binary complexes with their product SAM allow for a comparison with the Escherichia coli and rat structures. This facilitates the understanding of the different substrate or product conformations, mediated by the neighbouring gating loop, which can be accommodated by the compact active site during catalysis. The structure of MAT2B reveals an SDR (short-chain dehydrogenase/reductase) core with specificity for the NADP/H cofactor, and harbours the SDR catalytic triad (YxxxKS). Extended from the MAT2B core is a second domain with homology with an SDR sub-family that binds nucleotide-sugar substrates, although the equivalent region in MAT2B presents a more open and extended surface which may endow a different ligand/protein-binding capability. Together, the results of the present study provide a framework to assign structural features to the functional and catalytic properties of the human MAT proteins, and facilitate future studies to probe new catalytic and binding functions.
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Waligóra, Janusz. "Wizja ponadlokalna... O Praktykach czytania Grażyny B. Tomaszewskiej." Annales Universitatis Paedagogicae Cracoviensis. Studia ad Didacticam Litterarum Polonarum et Linguae Polonae Pertinentia 11, no. 315 (2020): 165–78. http://dx.doi.org/10.24917/20820909.11.13.
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The following article is a review of Grażyna Tomaszewska’s book entitled Praktyki czytania. Ponowoczesna interpretacja a szkoła (Gdańsk 2019). One of the major advantages of this publication is a contextual teaching strategy. Not only does it help to define the subject area of the text but also enables the reader to go beyond the presence and relate to the tradition, which tends to be a tough task in school reality. Thanks to an interesting mixture of the cultural texts, the localness (in the form of separateness and distinction) can mirror itself in a wider historical perspective. As a result, both the old and the contemporary show the quality of universality. In order to broaden the contexts, Tomaszewska also uses (post) modern interpretation theories (feminism, postcolonialism), which give the texts a fresh look and revise previous interpretations.
 Being impressive theoretically-wise as it is (literary theory, literary science, didactics), Tomaszewska’s book still seems to have more powerful impact in practical aspects. Here, we can witness how interpretations of cultural texts are created, how they surprise and provoke. The author picks contemporary poems of Szymborska, Hartwig, Miłosz and Herbert along with Wiesław Myśliwski’s prose (Kamień na kamieniu) and Jacek Dehnel’s novel Matka Makryna. Recapturing of the tradition is presented through the books and heroes of Romanticism (including the mother Makryna), which, once again, proved to be a sense-making and life- giving movement that raises questions and brings meanings.
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Mancini, Maicol, Laura Papon, Alain Mangé, Florence Cammas, and Eric Fabbrizio. "HP1s modulate the S-Adenosyl Methionine synthesis pathway in liver cancer cells." Biochemical Journal 477, no. 5 (2020): 1033–47. http://dx.doi.org/10.1042/bcj20190621.
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Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer in adults. Among the altered pathways leading to HCC, an increasing role is attributed to abnormal epigenetic regulation. Members of the Heterochromatin Protein (HP1) 1 family are key players in chromatin organisation, acting as docking sites for chromatin modifiers. Here, we inactivated HP1α in HepG2 human liver carcinoma cells and showed that HP1α participated in cell proliferation. HP1α-depleted cells have a global decrease in DNA methylation and consequently a perturbed chromatin organisation, as exemplified by the reactivation of transcription at centromeric and pericentromeric regions, eventhough the protein levels of chromatin writers depositing methylation marks, such as EZH2, SETDB1, SUV39H1, G9A and DNMT3A remained unaltered. This decrease was attributed mainly to a low S-Adenosyl Methionine (SAM) level, a cofactor involved in methylation processes. Furthermore, we showed that this decrease was due to a modification in the Methionine adenosyl transferase 2A RNA (MAT2A) level, which modifies the ratio of MAT1A/MAT2A, two enzymes that generate SAM. Importantly, HP1α reintroduction into HP1α-depleted cells restored the MAT2A protein to its initial level. Finally, we demonstrated that this transcriptional deregulation of MAT2A in HP1α-depleted cells relied on a lack of recruitment of HP1β and HP1γ to MAT2A promoter where an improper non-CpG methylation site was promoted in the vicinity of the transcription start site where HP1β and HP1γ bound. Altogether, these results highlight an unanticipated link between HP1 and the SAM synthesis pathway, and emphasise emerging functions of HP1s as sensors of some aspects of liver cell metabolism.
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Lu, Shelly C., and José M. Mato. "S-adenosylmethionine in Liver Health, Injury, and Cancer." Physiological Reviews 92, no. 4 (2012): 1515–42. http://dx.doi.org/10.1152/physrev.00047.2011.
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S-adenosylmethionine (AdoMet, also known as SAM and SAMe) is the principal biological methyl donor synthesized in all mammalian cells but most abundantly in the liver. Biosynthesis of AdoMet requires the enzyme methionine adenosyltransferase (MAT). In mammals, two genes, MAT1A that is largely expressed by normal liver and MAT2A that is expressed by all extrahepatic tissues, encode MAT. Patients with chronic liver disease have reduced MAT activity and AdoMet levels. Mice lacking Mat1a have reduced hepatic AdoMet levels and develop oxidative stress, steatohepatitis, and hepatocellular carcinoma (HCC). In these mice, several signaling pathways are abnormal that can contribute to HCC formation. However, injury and HCC also occur if hepatic AdoMet level is excessive chronically. This can result from inactive mutation of the enzyme glycine N-methyltransferase (GNMT). Children with GNMT mutation have elevated liver transaminases, and Gnmt knockout mice develop liver injury, fibrosis, and HCC. Thus a normal hepatic AdoMet level is necessary to maintain liver health and prevent injury and HCC. AdoMet is effective in cholestasis of pregnancy, and its role in other human liver diseases remains to be better defined. In experimental models, it is effective as a chemopreventive agent in HCC and perhaps other forms of cancer as well.
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Kim, Jung-Taek, Jun Han, Sumin Lim, Quan Hu Shen, and Ye Yeon Won. "Kinematically Aligned TKA Aligns the Ankle Joint Line Closer to Those of the Native Ankle than Mechanically Aligned TKA in Bipedal Stance." Journal of Knee Surgery 32, no. 10 (2019): 1033–38. http://dx.doi.org/10.1055/s-0039-1694796.
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AbstractMechanically aligned total knee arthroplasty (MATKA) aims to make alignment of the hip, knee, and ankle straight unexceptionally. However, emerging evidence suggests that unexceptional straightening the mechanical axis of the lower limb may lead to clinical and radiological problems of the ankle joint. By contrast, kinematically aligned total knee arthroplasty (KATKA) strives to restore the articular surface of the prearthritic knee. In this study, we examined results from KATKA and MATKA to determine which surgery restores the ankle joint orientation closer to the native ankle joint in bipedal stance and hypothesized that KATKA, rather than MATKA, would be more effective. Data from long-leg standing radiographs of 60 healthy adults (control group, n = 120 knees), patients who underwent MATKA (n = 90 knees), and patients who underwent KATKA (n = 90 knees) were retrospectively reviewed. The hip–knee–ankle angle, orientation of the tibial plafond and the talar dome relative to the ground (G-plafond and G-talus, respectively), and orientation of the plafond relative to the mechanical axis of the limb (M-plafond and M-talus, respectively) were measured and analyzed for comparison. Results show that bipedal stance alignment in patients who underwent KATKA (G-plafond: −0.65 ± 3.03 and G-talus: −1.72 ± 4.02) were not significantly different to native ankle joint alignment indicated by the control group. Compared with the native ankle joint measured in the control group (G-plafond: −0.76 ± 2.69 and G-talus: −1.30 ± 3.25), the tibial plafond and talar dome significantly tilted laterally relative to the ground in ankle joints after MATKA (G-plafond: −2.32 ± 3.30 and G-talus: −2.97 ± 3.98, p = 0.001 and p = 0.004, respectively). Thus, postoperative ankle joint line orientation after KATKA was horizontal to the floor and closer to that of native ankle joints than those after MATKA. The level of evidence is Level III.
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Ansari, Juned, Hemant Pandit, and Tsuneari Takahashi. "Kinematically Aligned Total Knee Arthroplasty or Mechanically Aligned Total Knee Arthroplasty." Journal of Knee Surgery 31, no. 10 (2018): 999–1006. http://dx.doi.org/10.1055/s-0038-1632378.
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AbstractKinematically aligned total knee arthroplasty (KATKA) was developed to more anatomically align the knee prosthesis to restore the native alignment of the knee and promote physiological kinematics. Even though there are concerns with implant survival, and follow-up at 10 years or more after KATKA has not been reported, there is a negligible incidence of failure of a tibial component at 2 to 9 years. Early clinical results with this technique are encouraging and demonstrate better functional outcomes compared with mechanically aligned TKA (MATKA). The purpose of this study is to perform a systematic review and meta-analysis of the literature to determine whether there are any clinical differences between KATKA and MATKA. The authors conducted a systematic review of the English literature. Five randomized controlled trials (RCTs) which compared clinical outcomes of KATKA and MATKA were finally included. Four RCTs used patient-specific instrument, and one RCT used navigation. Data were extracted and meta-analysis was conducted. KATKA patients had better outcomes: Mean difference between KATKA and MATKA and p-value are presented in brackets after each variable: the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) (–12.5; p < 0.0001), Oxford Knee Score (OKS) (2.3; p = 0.030), combined Knee Society Score (C-KSS) (13.1; p < 0.0001), Knee Function Score (KFS) (6.4; p = 0.0070), and postoperative range of motion (ROM) (4.1°; p = 0.0010). There was no significant difference concerning the complication rates which needed reoperations or revision surgery (odds ratio, 1.01; p = 0.99). KATKA components had a more femoral valgus (–1.8°; p < 0.0001), more tibial varus (1.2°; p = 0.0001), and more tibial slope (1.2°; p = 0.0001), all being statistically significantly different. Better clinical outcomes were obtained in KATKA and component placement in KATKA is significantly different from that in MATKA. There was no increase of patients with poor clinical results due to implant position especially for varus placement of tibial component. This systematic review of five RCTs suggests that KATKA is of potential alternative method to MATKA since the risk of revision for tibial loosening is negligible compared with MATKA for the same follow-up period.
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Aslikhah. "Sinergitas Program Matoanisasi Pada Masyarakat Desa Gunting Melalui Participatory Rural Appraisal (PRA)." SOEROPATI 2, no. 1 (2019): 61–70. http://dx.doi.org/10.35891/js.v2i1.1779.
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To Sukorejo The City of Matoa, Sukorejo subdistrict always distributes Matoa tree seedlings from year to year, which is spread in 19 villages, one of which is the Scissors village which is the first ring in spreading Matoa tree seedlings. However, Gunting villagers still do not know more about the types or benefits of these Matoa trees and fruits. This program takes the theme of entrepreneurship which will be implemented in Gunting village of Sukorejo Sub-district of Pasuruan Regency using the Participatory Rural Appraisal (PRA) method. The purpose of this program is to increase the understanding of Gunting village community on the use of Matoa trees and fruits so that they have high economic value. The results of this program are the community ranging from adults to children more familiar with Matoa fruit and Matoa trees, as well as variants of products from processed Matoa fruit. In addition to these results, this assistance also resulted in an attractive way of packaging products, as well as an understanding of the procedures for obtaining products that have SNI standards
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Hutagalung, Dyan Yosephin, Anni Holila Pulungan, and Rahmad Husein. "INTERTEXTUALITY REALIZATION IN SARI MATUA CEREMONY." LINGUISTIK TERAPAN 18, no. 1 (2021): 10. http://dx.doi.org/10.24114/lt.v18i1.25364.
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ABSTRACTThis study aims to describe the realization of intertextuality occurences in sari matua ceremony. This research is conducted qualitatively by applying technique analysis of Bazerman. The data are utterances which delivered by the speakers in the ceremony and transcribed into transcription. Sari Matua is one kind of death ceremony in batak toba culture and has been studied in other particular field of study. In this study, intertextuality occurrence are studied on oral discourse in Sari matua batak toba ceremony. Sari matua batak toba ceremony consisted of two sessions which are Martonggo Raja and main ceremony and this study focuses on these two sessions. The result of this study shows that there were 50 specific data found from 82 specific data which included kinds of intertextuality namely qutotation, reference, and allusion. The realization of intertextuality occurences in sari matua Batak Toba ceremony is realized by some elements of intertextuality itself. The realization Quotation is identified through the presence of lexical expressions such as mandok, manungkun, hatahononku, di dok, pinasihat. Reference is identified by seeing clause which reflected to, re-contextualized to dan re-accentuated to. Allusion is identified by clause complex which referring the text to literature, historical art, story, person even place. The intertextuality occurences realized in sari matua Batak Toba ceremony because the text which quoted, referred to and alluded to from the past time can be reflected in ourlives in the present time. Key words: Intertextuality, Oral Discourse, Batak Toba Ceremony, Sari Matua
Dissertations / Theses on the topic "Matka result"
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Maciel, Luiz Vicente Burle. "An?lise dos remanescentes de mata atl?ntica do Estado do Rio Grande do Norte : uma perspectiva em alta resolu??o." Universidade Federal do Rio Grande do Norte, 2011. http://repositorio.ufrn.br:8080/jspui/handle/123456789/14021.
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Previous issue date: 2011-07-08<br>The habitat loss and fragmentation are considered the main threats to the biodiversity. These threats operate at the landscape level, which drives the need to manage entire landscapes, not just its components. Although systematic monitoring of the Atlantic Forest biome has been ongoing since the late eighties, current data on forest fragmentation for the sub-region of Pernambuco are practically nonexistent. This study aimed to map out, with high spatial resolution, the remnants of Atlantic forest in Rio Grande do Norte, and conduct a landscape level analysis. The results show that the landscape is highly fragmented, where about 13.6% to 17% of biome remains. Most of the fragments is less than 10 ha, while a few fragments have area larger than 100 ha. Although the high degree of fragmentation, the average distance between fragments found was small (128 m), this estimate is lower than has been observed for the biome (1440m). There is evidence that abrupt changes in the quantification of landscape structure can occur when one observes the fragmentation at high spatial resolution. The results presented here can be used in management actions, in order to make the scenario more conducive to maintaining biodiversity.<br>A perda e fragmenta??o de habitat s?o consideradas as principais amea?as a biodiversidade. Essas amea?as atuam ao n?vel da paisagem, o que impele a necessidade de manejar paisagens por inteiro e n?o somente suas componentes. Embora o acompanhamento sistem?tico do bioma Mata Atl?ntica venha sendo feito desde o final da d?cada de oitenta, dados atualizados sobre fragmenta??o florestal para a sub-regi?o de Pernambuco s?o praticamente inexistentes. O presente estudo teve como objetivo mapear, sobre imagens de alta resolu??o espacial, os remanescentes do bioma Mata Atl?ntica no estado do Rio Grande do Norte e conduzir uma an?lise ao n?vel de paisagem. Os resultados mostram que a paisagem encontra-se altamente fragmentada, onde restam cerca 13,6% a 17% dos remanescentes florestais do bioma. A grande maioria dos fragmentos ? menor do que 10 ha, enquanto poucos fragmentos possuem ?rea maior do que 100 ha. Embora seja elevado o grau de fragmenta??o, a dist?ncia m?dia entre fragmentos encontrada foi pequena (128 m), essa estimativa ? menor do que a que tem sido observada para o bioma (1440m). H? ind?cios de que mudan?as bruscas na quantifica??o da estrutura da paisagem podem ocorrer quando se observa a fragmenta??o em alta resolu??o espacial. Os resultados aqui apresentados podem ser utilizados em a??es de manejo, com vistas a tornar o cen?rio mais prop?cio ? manuten??o da biodiversidade.
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DAŇKOVÁ, Martina. "Pedagogický přístup k dítěti s ADHD - reflexe vlastní zkušenosti." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-381454.
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In this Master Thesis, I inquire into pedagogical approach towards a child with ADHD syndrome. I focus on one specific child that I previously worked with. I consider this personal experience as valuable and uncommon. That is reason I would like to express the gravity of pedagogical approach towards an ADHD child. The research problem originates from my own practice and a direct confrontation with the child. In the theoretical part, I deal with the problematics of ADHD syndrome. I focus on the causes of development and effects of the syndrome on the life of the child. I also focus on establishing a diagnosis of ADHD, and on its treatment. I dedicate one chapter on rearing and methods of rearing according to Zdenek Matejcka, a child psychologist. I describe inclusive education in relation to ADHD pupils, based on the current state of Czech school system. The practical part is dedicated to the research of my work. I specify my research design and method. I apply methods of observation, interviews, and describe their results. Moreover, I deal with the results of interviews with pedagogical assistants and with pedagogues that worked or still work with the ADHD pupil. Results of the observations and other methods of data collection that I name in the methodology part form a basis of the research problem of this work.
Books on the topic "Matka result"
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SATTA MATKA | KALYAN MATKA | 7049469905 | SATTA KING | MATKA RESULT: Kalyan MATKA fix SINGAL Jodi Patti call 7049469905 ❋ Satta Matka ❋ Satta Matka Results ❋ SattaMatka ❋ Matka tips ❋ Free Matka Results ❋ Kalyan Matka Results ❋ Satta Game ❋ Matka Game ❋ Mumbai Main ❋ Kalyan Results ❋ Kalyan Chart ❋ Main Mumbai Chart ❋ Online Matka Results ❋ Satta Matka Tips ❋ Milan Chart ❋ Old Satta chart ❋ Top Matka Guess ❋ Matka Links ❋ Live Satta Matka Results ❋ Satta Matka Number ❋ Satta Matka Software ❋ Matka Chart ❋ Matka ❋ Free Matka Guessing ❋. SATTA MATKA | KALYAN MATKA | 7049469905 | MATKA RESULT | SATTA KING | KAPIL MATKA |, 2018.
Find full textBook chapters on the topic "Matka result"
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Türk, Ersin, Aygün Erdoğan, Beytullah Sulak, and Gökhan Hüseyin Erkan. "The Impact of COVID-19 on the Rural Second Home Tourism." In Handbook of Research on the Impacts and Implications of COVID-19 on the Tourism Industry. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-8231-2.ch034.
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The aim of this study is to examine the level of satisfaction of second home users in the EBSR countryside due to the COVID-19 pandemic. For this purpose, a qualitative research based on in-depth interview technique using semi-structured questionnaire was applied to six households. Gürgenağaç Village within the borders of Trabzon Province, Maçka District was selected as the case area. The study provided results to discuss whether rural second homes, which are seen as insurance against risks, fulfill the expected task by virtue of the global pandemic experience and the problems arising from second homes and their surroundings. In conclusion, the study shows that behaviors and attitudes of rural second home owners had significantly changed with the COVID-19 pandemic.
Conference papers on the topic "Matka result"
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Son, Hyoung M., and Kune Y. Suh. "Solution to a Standard Thermal Hydraulics Problem in a Liquid Metal Subassembly." In 14th International Conference on Nuclear Engineering. ASMEDC, 2006. http://dx.doi.org/10.1115/icone14-89188.
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The model subassembly of the BREST-type reactor core consists of a pin bundle of square arrangement. In this bundle there are two zones which differ in the pin diameter and heat production. The model pin bundle contains one spacer grid which is located near the mid-plane of the rod bundle geometry. The working is a eutectic alloy of 22% sodium (Na) plus 78% potassium (K). Three kinds of experiments were performed to observe the thermal and hydraulic behavior of the liquid metal coolant in the BREST core simulator. Results were obtained for the coolant exit temperature distribution, central measuring pin simulator external surface temperature distribution, and coolant velocity distribution over the perimeter of the measuring pin simulator. The experiments were performed five times with increasing pin power ratios. Analysis was performed on the model subassembly of the BREST-type reactor core using a subchannel analysis code MATRA and a computational fluid dynamics code CFX. Calculational results were compared against the experimental data. The experiment revealed that the temperature rise was strongly dependent upon the geometry of the pin simulator. In contrast to the experimental results, the MATRA results were mainly dependent upon the thermal and hydraulic conditions. It was concluded that MATRA requires modifications for the pressure drop correlations that were considered inappropriate for accurately simulating the coolant behavior near the BREST-type grid spacer. Hand calculations were additionally carried out under different assumptions to determine the coolant exit temperature distribution in the pin simulator. First, the hand calculation was performed to find the coolant exit temperature distribution assuming that there is no momentum or energy transfer between subchannels. Second, an assumption was made that the coolant mixing in the subchannel assembly took place instantaneously and the pressure was equilibrated at the channel exit. Since MATRA is based on a lumped parameter model, it only calculates the subchannel averaged velocity values. Here, CFX based on the finite volume method was utilized to calculate the velocity fields over the perimeter. Results from the experiment and CFX were averaged in each subchannel region so as to check on the tendency. The CFX analysis showed reasonable results which can be improved by imposing more detailed geometry accounting for the angle of the inclination of the grid spacer.
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Gu¨rtner, Arne, and Joachim Berger. "Results From Model Testing of Ice Protection Piles in Shallow Water." In 25th International Conference on Offshore Mechanics and Arctic Engineering. ASMEDC, 2006. http://dx.doi.org/10.1115/omae2006-92100.
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The development of oil and gas fields in shallow icy waters, for instance in the Northern Caspian Sea, have increased the awareness of protecting offshore structures by means of ice barriers from the impacts of drifting ice. Protection could be provided by Ice Protection Piles (IPPs), installed in close vicinity to the offshore structure to be protected. Piles then take the main loads from the drifting ice by pre-fracturing the advancing ice sheet. Hence, the partly shielded offshore structure could be designed according to significant lower global design ice loads. In this regard, various configurations of pile arrangements have been model tested during the MATRA-OSE research project in the Ice Model Test Basin of the Hamburg Sip Model Basin (HSVA). The main objective was to analyse the behaviour of ice interactions with the protection piles together with the establishment of design ice loads on an individual pile within the pile arrangement. The pile to pile distances within each arrangement were varied from 2 to 8 times the pile diameter for both, vertical and inclined (30° to the horizontal) pile arrangements. Two test runs with 0.1 m and 0.5 m thick ice (full scale values) were conducted respectively. The full scale water depth was 4 m. Based on the model test observations, it was found that the rubble generation increases with decreasing pile to pile distances. Inclined piles were capable to produce more rubble than vertical piles and considerable lower ice loads were measured on inclined arrangements compared to vertical arrangements. As initial rubble has formed in front of the arrangements, the rubble effect accelerated considerable. Subsequent to the build-up of rubble accumulations, no effect of the pile inclination on the exerted ice loads could be observed. If piles are used as ice barriers, the distance between the piles should be less than 4D for inclined piles and 6D for vertical piles to allow sufficient rubble generation. Larger distances only generated significant ice rubble after initial grounding of the ice had occurred.
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Dos Anjos, Jean Nascimento, and Eduardo Mariano Neto. "EFEITOS DA PERDA DE HABITAT SOBRE AS FUNÇÕES ECOLÓGICAS DE PLANTAS LENHOSAS DA MATA ATLÂNTICA." In I Congresso Brasileiro de Biodiversidade Virtual. Revista Multidisciplinar de Educação e Meio Ambiente, 2021. http://dx.doi.org/10.51189/rema/1084.
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Introdução; A perda de habitat é a principal causa da perda contínua de biodiversidade em todo o mundo. Fundamentalmente, está cada vez mais claro que as perdas na cobertura florestal em escalas de paisagem resultam em mudanças substanciais em uma série de processos ecológicos e funções do ecossistema que, em última instância, determinam a trajetória futura de muitas das florestas mais diversas e ameaçadas do mundo. Objetivos; Buscamos nesse estudo avaliar a resposta da riqueza taxonômica e diversidade funcional de plantas lenhosas da Mata Atlântica frente a perda de habitat na escala da paisagem, bem como, avaliar o modelo que melhor descreve o comportamento dessas relações. Material e métodos; Esse estudo foi realizado em onze paisagens de 6 x 6 km (36 km²) com diferentes proporções de cobertura florestal (entre 5% e 60%) na Mata Atlântica da Bahia. Foram estabelecidas oito parcelas de 250 m² aleatoriamente escolhidas em cada paisagem, e amostrados ramos de todos os indivíduos lenhosos com circunferência acima do peito (CAP) igual ou superior a 8 cm. A classificação das espécies por característica funcional foi baseada em livros, dissertações, teses, artigos científicos e banco de dados ecológicos virtuais. O s modelos foram selecionados com base no critério de informação de Akaike e (ΔAIC). Resultados; A redução da cobertura florestal na escala da paisagem afetou negativamente a riqueza taxonômica e funcional e essas relações foram não lineares (modelo de potência) . A uniformidade funcional não respondeu a quantidade de cobertura de floresta na paisagem (modelo nulo). Já a divergência funcional respondeu positivamente dentro desse cenário (modelo de potência). Conclusão; Os efeitos da perda de habitat de floresta sobre a comunidade de plantas lenhosas da Mata Atlântica e suas funções associadas tem implicações importantes para a conservação em paisagens humanamente modificadas. Nosso modelo demonstra perda significativa da riqueza de espécies quando a quantidade de floresta é reduzida. Ademais, a riqueza funcional também demonstrou ser duramente penalizada pela redução da perda de floresta na paisagem. Tendo em vista que a riqueza taxonômica, riqueza funcional e redundância funcional são aspectos importantes para manutenção e resiliência dos ecossistemas, essas respostas frente a perda de habitat de floresta em escala de paisagem, colocam em xeque a permanência a longo prazo da comunidade lenhosa megadiversa e suas funções associadas na Mata Atlântica.
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Anjos, Jean Nascimento Dos, and Eduardo Mariano Neto. "PERDA DE HABITAT FLORESTAL E RESPOSTA DA COMUNIDADE DE PLANTAS LENHOSAS DA MATA ATLÂNTICA." In II Congresso Brasileiro de Ciências Biológicas On-line. Revista Multidisciplinar de Educação e Meio Ambiente, 2021. http://dx.doi.org/10.51189/rema/1279.
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Introdução. A perda de habitat é a principal causa da perda contínua de biodiversidade em todo o planeta. Fundamentalmente, está cada vez mais claro que as perdas na cobertura florestal em escalas de paisagem resultam em mudanças substanciais em uma série de processos ecológicos e funções do ecossistema que, em última instância, determinam a trajetória futura de muitas das florestas mais diversas e ameaçadas do mundo. Tradicionalmente, as mudanças na biodiversidade têm sido avaliadas pela riqueza e uniformidade de espécies. Contudo, a diversidade funcional é um impulsionador chave dos processos do ecossistema, influenciando tanto a função quanto a confiabilidade do ecossistema. Objetivos. Objetivamos avaliar a resposta da riqueza taxonômica e diversidade funcional de plantas lenhosas da Mata Atlântica frente a perda de habitat florestal na escala da paisagem. Material e Métodos. Esse estudo foi realizado em onze paisagens de 36 km² com diferentes proporções de cobertura florestal (entre 5% e 60%) na Mata Atlântica da Bahia. Estabelecemos 8 parcelas de 250 m² aleatoriamente escolhidas em cada paisagem, onde amostramos ramos das plantas lenhosas com CAP superior a 8 cm. A classificação das espécies por característica funcional foi baseada em livros, teses, artigos científicos e bancos de dados virtuais. Avaliamos a riqueza taxonômica e 3 métricas de diversidade funcional: riqueza funcional (FRic), uniformidade funcional (FEve) e divergência funcional (FDiv). Resultados. A perda de cobertura florestal na escala da paisagem influenciou negativamente a riqueza taxonômica e funcional. A uniformidade funcional não respondeu a perda de floresta na paisagem, indicando que a homogeneidade de distribuição das características funcionais no espaço funcional se mantém independentemente da quantidade de habitat na paisagem. Contudo, a divergência funcional foi positivamente influenciada pela redução da cobertura florestal na escala da paisagem, sugerindo perda de redundância funcional em função do aumento da perda de habitat. Conclusão. Tendo em vista que a riqueza taxonômica, riqueza funcional e redundância funcional são aspectos importantes para manutenção e resiliência dos ecossistemas, essas respostas a perda de habitat de floresta em escala de paisagem, colocam em xeque a permanência a longo prazo da comunidade lenhosa megadiversa e suas funções associadas na Mata Atlântica.
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Muscatello, Giovanna. "La torre nella torre. Recupero e rilievo 3D per la fruizione della Torre Matta ad Otranto." In FORTMED2020 - Defensive Architecture of the Mediterranean. Universitat Politàcnica de València, 2020. http://dx.doi.org/10.4995/fortmed2020.2020.11357.
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The tower in the tower. Recovery and 3D survey for virtual visits to the Torre Matta in OtrantoOtranto is one of the biggest ancient settlements in the Salento (Puglia), in the easternmost part of the Italian peninsula. This location has always affected the city’s history, which has a stratified system of defence. As a result of the Turkish invasion of 1480, the city was completely destroyed. During the counter-offensive of 1481 the city was reconquered by the Aragonese, who are credited with the reconstruction of the city and its defences, building high walls with circular towers (still visible and well conserved), which housed artillery pieces on the various floors of the casemates. Around the mid sixteenth century the existing defensive structures were enriched with bastions including the imposing pentagonal structure that incorporates the circular tower of the late fifteenth century, the so-called Torre Matta, facing the harbour. As part of recent recovery measures, the enormous room inside the bastion was completely emptied. This entailed removing all the accumulated material which, over the years, had come to fill the entire space. This material obscured the external wall of the fifteenth century tower enclosed within the bastion, of which, at the beginning of the work, only the stone corbels and the blind arches at the top were visible. The material had also prevented access via the only original entrance, on the south-east side, which was on the level of the moat. The stratified deposits to be removed were about 18 m deep, and the operation served to bring to light the entire room and the tower, making it possible for the first time to appreciate the relationship between the walls. To record the geometry of the individual architectural features, a 3D laser scan was performed, integrated with direct surveys. A three-dimensional model was created in order to enable virtual visits and disseminate knowledge of the monument.
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Chang, Won-Pyo, Kwi-Seok Ha, Kwi-Lim Lee, and Hae-Yong Jeong. "The Analysis of Partial Flow Blockage Accidents for a Sodium Cooled Fast Reactor." In 2012 20th International Conference on Nuclear Engineering and the ASME 2012 Power Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/icone20-power2012-54914.
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Analyses were performed for flow blockage accidents postulated in a conceptual design of a 600 MWe demonstration sodium cooled fast reactor with 3 types of core designs, i.e., Uranium, *L-TRU (TRansUrium) and **M-TRU cores, using the MATRA-LMR-FB code. The analysis was addressed for the 6 sub-channel blockage which is a design basis event (DBE). The accidents for 24 and 54 sub-channel blockages were also analyzed to estimate the extent of the blockage size which could lead to sodium boiling or fuel melting. Three radial blockage positions were also taken into account in the analysis. In result, a higher maximum coolant temperature in the subassembly was obtained as the number of blocked subchannels increased. A recirculation region was usually developed right above the blockage for large blockage cases. The analysis results showed that a favorable safety margin was assured for the design basis event, i.e., the 6 sub-channel blockage accident. For the 24 and 54 sub-channel blockage cases, the peak cladding temperature limit was breached, and there was a case in which fuel melting could be threatened. * TRU extracted from LWR fuel ** Mixture of L-TRU and TRU extracted from self-recycled SFR fuel
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Ulko, D. O., I. I. Gureyeva, R. S. Romanets, and A. A. Kuznetsov. "Molecular-phylogenetic analysis of the Cystopteridaceae family from North Asia based on plastid DNA loci." In Problems of studying the vegetation cover of Siberia. TSU Press, 2020. http://dx.doi.org/10.17223/978-5-94621-927-3-2020-40.
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The results of molecular phylogenetic studies based on the sequencing of matK gene and trnG-R intergenic spacer of the chloroplast DNA and analysis of the concatenated data of these loci of North Asian representatives of the Cystopteridaceae family are presented. In the genus Gymnocarpium, a dryopteris-clade was distinguished including species without glandular pubescence of fronds – Gymnocarpium dryopteris. Species having glandular pubescent fronds have formed the robertianum-clade (G. robertianum and G. fedtschenkoanum), and 2 subclades, including G. continentale, G. jessoense, and G. tenuipes. In the genus Cystopteris, the analysis confirmed the separation of C. montana from other Cystopteris species, and the separation of C. sudetica from the C. fragilis-complex. This advocate the recognition of monotypic genus Rhizomatopteris including Rh. montana (≡Cystopteris montana), and allows to recognize the section Khokhrjakovia (with C. sudetica) within the genus Cystopteris. This analysis did not allow to separate the species of the type subgenus Cystopteris (C. fragilis-complex) from each other.
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Góes, Bruna Delgado, Alana Padia Cavalcante, Daniele Cassiano Feliciano, João Fernando Marques Da Silva, and Sara Mataroli De Godoy. "ENDOGAMIA E ESTRUTURA POPULACIONAL EM CAMPOMANESIA XANTHOCARPA EVIDENCIAM DECLÍNIO FUTURO DA DIVERSIDADE GENÉTICA DA ESPÉCIE." In II Congresso Brasileiro de Ciências Biológicas On-line. Revista Multidisciplinar de Educação e Meio Ambiente, 2021. http://dx.doi.org/10.51189/rema/1229.
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Introdução: A Mata Atlântica é reconhecida como um dos biomas brasileiros mais importantes, devido sua grande biodiversidade e grau de endemismos. Entretanto, ao longo das últimas décadas, este bioma tem sofrido um intenso processo de fragmentação, o que torna a floresta remanescente cada vez mais desconexa. O comprometimento do fluxo gênico entre os fragmentos isolados afeta sobremaneira a dinâmica populacional das espécies, reduzindo a capacidade de adaptação das mesmas frente às mudanças ambientais. Campomanesia xanthocarpa O. Berg. (Myrtaceae) é uma espécie arbórea frutífera, conhecida popularmente como gabiroba, guavirova, guabiroba-miúda e guabirobeira-do-mato, de ocorrência no bioma Mata Atlântica, sendo utilizada em programas de recuperação de áreas degradadas e de ambientes ripários. Além disso, sua madeira é usada na produção de instrumentos musicais, agrícolas, como cabo de ferramentas, carvão, etc. Objetivo: Estimar os índices de diversidade e estrutura genética de populações naturais de C. xanthocarpa em fragmentos florestais. Material e Métodos: Foram aplicados oito locus SSR em sete populações da espécie, totalizando 172 plantas, distribuídas em Unidades de Conservação (UC’s) e outras em áreas não protegidas do estado do Paraná. Resultados: Índices moderados de diversidade genética e altos de estruturação populacional foram observados, além de, relativamente, pouco fluxo gênico entre as populações e valores positivos e significativos do coeficiente de endogamia. Discussão: Apesar de moderado, os índices de diversidade genética não diferiram entre as populações situadas em UC e as de ocorrência em áreas não protegidas. Os baixos níveis de fluxo gênico resultam do processo de fragmentação do bioma em que a espécie ocorre, e favorecem o aumento na frequência de cruzamentos entre indivíduos aparentados, elevando, consequentemente, a estruturação populacional e os níveis de endogamia. A longo prazo, a endogamia tende a reduzir os níveis de diversidade genética, reduzindo também o valor adaptativo das populações. Conclusão: As populações de C. xanthocarpa, mesmo exibindo níveis moderados de diversidade genética, se apresentam estruturadas, com níveis consideráveis de endogamia e, relativamente, baixos de fluxo gênico, o que evidencia a necessidade de estratégias de conservação e manejo, como forma de impedir o declínio futuro da diversidade genética da espécie.
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Weihrauch, Alexandra, Joachim Berger, and Marc Bartels. "Ice Loading of Jack-Up Platforms." In ASME 2005 24th International Conference on Offshore Mechanics and Arctic Engineering. ASMEDC, 2005. http://dx.doi.org/10.1115/omae2005-67285.
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The use of drilling platforms for exploration drillings in ice-covered shallow water is expected to increase in the future. Jack-up platforms (JU) are regarded to be most suitable for exploration drillings due to their high mobility, their facile transportation and installation. Although having proved their capability for harsh environments, e.g. in the North Sea, jack-ups have neither been especially designed for nor have been operated frequently in icy waters. The problems associated with the operation of jack-ups in ice waters are related to structural integrity as well as to operational limitations. One objective of the research project MATRA-OSE was to check the design of JU for exploration and oil production in ice-covered, shallow-water areas. The global stability of JU as well as local and global loads acting on a three-legged jack-up drilling unit were investigated. The design loads were determined by analytical approaches. Different ice load cases were defined as the basis for the detail design. These load cases include local loads on single members of the platform legs like chords or braces as well as global loads, which may act on one individual leg or on several legs of the platform. Vertical forces, which result from a change of the water level (up-surge and down-surge) in case ice sheets are frozen to the platform legs were considered. Also the impact of ice being jammed between the platform legs was investigated. It has been found out that the most critical load case results from the ice being jammed between the platform legs. It should therefore be tried in practice to avoid the ice jamming by proper ice management, as the large ice loads calculated for this scenario may result in problems for the stability of a JU. Ice breakers could be used to pre break the ice and should try to clear the site from broken ice pieces before it starts to accumulate.
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Silva, Oscarina Teodora Prado Santos, Raquel Henrique, Nathan David Vogt, Maria Angélica Toniolo, and Mario Valério Filho. "PRESSÕES AMBIENTAIS E PERCEPÇÕES DE MORADORES NA BACIA DO RIO PARAÍBA DO SUL." In VI Seminário do Programa de Pós-graduação Planejamento Urbano e Regional. Universidade do Vale do Paraíba, 2021. http://dx.doi.org/10.18066/semplur2021.11.
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O presente resumo apresenta uma análise sobre a questão socioambiental acerca dos problemas ambientais na bacia do rio Paraíba do Sul, porção paulista, a partir de uma pesquisa quali-quantitativa com 339 moradores. Esta bacia compõe a Mata Atlântica, cujo 90% das florestas foram desmatadas nos últimos séculos (WILLIAMS, 2006). Atualmente, seus principais problemas ambientais são a as áreas de pastagens degradadas, em uso ou abandonadas, a monocultura de eucalipto, a ocupação urbana, irregular e saneamento precários, (DEVIDE et al., 2014; RONQUIM et al., 2016; SILVA et al. 2017,). Sendo assim, temos como problemática de pesquisa questionar sobre a paisagem regional frágil do ponto de vista ambiental e a capacidade de resiliência e adaptação da paisagem da bacia para choques climáticos extremos, como a crise hídrica de 2013-2015 que acometeu sobretudo a região (MENDES FILHO et al., 2016), a qual teve como consequência, em medida do governo do estado de São Paulo, efetivar a proposta transposição das águas do manancial Jaguari (bacia Paraíba do Sul) ao Atibainha (Sistema Cantareira) (MARENGO, ALVES, 2015), acentuando ainda mais a pressão para a resiliência deste recurso hídrico, que abastece as cidades do Vale do Paraíba, região metropolitana fluminense e agora também a capital paulista.