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Hamáček, Vojtěch. "Vývoj bezpilotního prostředku pro autonomní mise." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2021. http://www.nusl.cz/ntk/nusl-442528.
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The aim of this thesis is to modify commercially produced drone DJI Matrice 100 and replace its original control unit by open source Pixhawk and its accessories. Subsequently, it deals with the selection of suitable open source firmware for Pixhawk and its configuration on the device. Another part is dedicated to the possibilities of using the Robotic Operating System (ROS) and its Mavros libraries on the onboard computer Raspberry Pi. By using Mavros, it examines the possibilities of drone flight control, both in the simulation environment and in the real environment.
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Thilly, Ludovic. "Exploration theorique et experimentale de fils nanocomposites continus presentant des proprietes extremes de conductivite electrique et de limite elastique : application future : Coilin 100 t." Toulouse, INSA, 2000. http://www.theses.fr/2000ISAT0028.
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Des conducteurs renforces nanocomposites cuivre/niobium et cuivre/tantale ont ete elabores par etirage pour le developpement des bobines resistives de champs magnetiques pulses intenses, dont le cahier des charges impose une limite elastique maximale pour supporter les contraintes crees par les forces de lorentz et une conductivite electrique elevee pour une duree d'impulsion prolongee. L'etude de l'effet de la deformation et des basses dimensions a ete menee en parallele : - sur les proprietes mecaniques, en faisant appel aux techniques post-mortem de microscopie electronique (en transmission et haute resolution), atomique (sonde tomographique 3d) ainsi qu'a la technique de deformation in-situ en microscope electronique, revelant les mecanismes de la deformation dans ces nanostructures. La modelisation du comportement des dislocations a permis de simuler les proprietes mecaniques et de determiner les parametres structuraux d'optimisation. - sur la conductivite electrique afin d'en determiner les parametres d'optimisation. Ces parametres ont permis d'elaborer des conducteurs composes d'une matrice de cuivre contenant 52. 2 millions et 4. 4 milliards de nanowhiskers de niobium aux proprietes extremes. Parallelement, l'etude du systeme cuivre/tantale a revele des problemes de compatibilite de deformation dus a la difference de modules de cisaillement et caracterises par le developpement d'une rugosite interfaciale macroscopique menant a la fracture prematuree du tantale. Ce phenomene a ete etudie theoriquement et experimentalement selon le formalisme des instabilites de grinfeld. L'etude de deux modes de deformation (etirage et extrusion) a permis de definir une methode d'elaboration permettant l'elaboration de nanocomposites cuivre/tantale.
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Meyer, Gustavo da Costa. "A sustentabilidade em questão: paradigma ou matriz discursiva?" Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/100/100134/tde-13112015-140605/.
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Tendo como base contextual a crise ambiental contemporânea, a qual tem características de crise civilizatória, este trabalho teve como principal objetivo colocar em debate a noção de Desenvolvimento Sustentável (DS), visto que este importante conceito foi politicamente construído e consensuado de forma a ser a principal resposta para a questão ambiental. Dessa maneira, dado que a crise ambiental pede a emergência de um novo paradigma (o qual supere o chamado paradigma da simplificação), que leve em consideração uma mudança de cunho cognitivo, e compreenda o espaço em sua dinâmica de produção e reprodução da vida e em suas múltiplas territorialidades, esta pesquisa buscou analisar a possível constituição da sustentabilidade como este paradigma complexo, ou, ao contrário, se tal noção se resume a uma matriz discursiva que, como tal, obscurece as principais questões que deveriam ser consideradas por um paradigma da complexidade com um, conseqüente, novo aporte teórico-metodológico. Nesse sentido, o caminho metodológico traçado incluiu a discussão das diferentes concepções acerca das noções de matriz discursiva e paradigma, relacionando-se, posteriormente, tais temáticas com a questão ambiental e com a noção de DS em si, em seu viés político e científico. Apesar de dúvidas permanecerem, se considerou que a sustentabilidade parece, realmente, se apresentar muito mais como uma matriz discursiva do que como um paradigma, integrando uma matriz discursiva do meio ambiente. Assim, se pode apontar que o DS se encontra delimitado em um campo institucional específico, com pesquisas e políticas públicas orientadas e influenciadas pelos agentes determinantes hegemônicos de tal campo, como o Banco Mundial, por exemplo. Estes, de acordo com determinada visão de desenvolvimento (como sinônimo de crescimento econômico e se utilizando do viés da economia neoclássica) e da problemática ambiental (relegada a uma questão de gestão ou planejamento ambiental adequado, sem maiores entendimentos com relação a dinâmica territorial em sua totalidade) influenciam os discursos que devem permear o campo ambiental, pautando, inclusive, o conhecimento científico. A noção de DS colocada desta forma não representa, assim, qualquer ruptura com o paradigma da simplificação, sendo apenas uma matriz discursiva que encobre (e desenvolve na prática) o núcleo de tal paradigma, influenciando a práxis dos diversos agentes sociais presentes nos territórios. Como possíveis rupturas com a matriz discursiva do meio ambiente, se procurou apresentar e discutir, também, duas linhas de pensamento, ou coletivos do pensamento, que se apresentam como possíveis novos aportes teórico-metodológicos, condizentes, talvez, com um paradigma da complexidade que leve em conta, principalmente, as noções de totalidade e de complexidade ambiental<br>With the contextual basis the contemporary environmental crisis, which has characteristics of civilizing crisis, this work aimed to put in discussion the idea of Sustainable Development (SD); following that, this important concept has been politically built and conceived in order to be the main answer to this environmental issue. Therefore, since the environmental crisis asks for the emergence of a new paradigm (which exceeds the so-called paradigm of simplification), that takes into account a change of cognitive mark and take in the space in its dynamics of production and reproduction of life and in their multiple territories. This research sought to check over the possible formation of sustainability as this complex paradigm, or, oppositely, if such notion comes down to a discursive matrix that, as such obscures the mains issues that should be considered by a paradigm of complexity and, consequently, new theoretical and methodological support. In this sense, the trace of methodological approach included the discussion of different conceptions about the notions of discourse and paradigm matrix, relating subsequently such topics to environmental issues and the notion of SD itself in its political and scientific bias. Although doubts remain, it was taken into account that the sustainability seems to really perform much more as a discursive matrix than a paradigm, which integrates a discursive matrix of the environment. Consequently, one can point that the SD is found in a limited specific institutional field, with research and policy oriented and influenced by hegemonic determinant agents of such a field, such as the World Bank, for instance. These, according to certain development vision (as a synonym for economic growth and using the bias of neoclassical economics) and environmental issues (relegated to a management issue or appropriate environmental planning, without further understandings with respect to territorial dynamics in your all) influence the discourses that should pass through the environmental field, guiding even scientific knowledge. The notion of SD placed in this way does not represent, so any break with the paradigm of simplification, just being a discursive matrix that covers (and develops in practice) the core of such paradigm, which influences the practice of various social agents present in the territories. Considering as possible disruptions to the discursive matrix of the environment, an attempt to present and discuss also two schools of thought, or collective thinking, posing as potential new theoretical and methodological contributions, observing perhaps with a paradigm of complexity that takes into account mainly the notions of wholeness environmental complexity
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Diaz, Alexandra Katiuska Ramos. "Biagrupamento heurístico e coagrupamento baseado em fatoração de matrizes: um estudo em dados textuais." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/100/100131/tde-12112018-182428/.
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Biagrupamento e coagrupamento são tarefas de mineração de dados que permitem a extração de informação relevante sobre dados e têm sido aplicadas com sucesso em uma ampla variedade de domínios, incluindo aqueles que envolvem dados textuais -- foco de interesse desta pesquisa. Nas tarefas de biagrupamento e coagrupamento, os critérios de similaridade são aplicados simultaneamente às linhas e às colunas das matrizes de dados, agrupando simultaneamente os objetos e os atributos e possibilitando a criação de bigrupos/cogrupos. Contudo suas definições variam segundo suas naturezas e objetivos, sendo que a tarefa de coagrupamento pode ser vista como uma generalização da tarefa de biagrupamento. Estas tarefas, quando aplicadas nos dados textuais, demandam uma representação em um modelo de espaço vetorial que, comumente, leva à geração de espaços caracterizados pela alta dimensionalidade e esparsidade, afetando o desempenho de muitos dos algoritmos. Este trabalho apresenta uma análise do comportamento do algoritmo para biagrupamento Cheng e Church e do algoritmo para coagrupamento de decomposição de valores em blocos não negativos (\\textit{Non-Negative Block Value Decomposition} - NBVD), aplicado ao contexto de dados textuais. Resultados experimentais quantitativos e qualitativos são apresentados a partir das experimentações destes algoritmos em conjuntos de dados sintéticos criados com diferentes níveis de esparsidade e em um conjunto de dados real. Os resultados são avaliados em termos de medidas próprias de biagrupamento, medidas internas de agrupamento a partir das projeções nas linhas dos bigrupos/cogrupos e em termos de geração de informação. As análises dos resultados esclarecem questões referentes às dificuldades encontradas por estes algoritmos nos ambiente de experimentação, assim como se são capazes de fornecer informações diferenciadas e úteis na área de mineração de texto. De forma geral, as análises realizadas mostraram que o algoritmo NBVD é mais adequado para trabalhar com conjuntos de dados em altas dimensões e com alta esparsidade. O algoritmo de Cheng e Church, embora tenha obtidos resultados bons de acordo com os objetivos do algoritmo, no contexto de dados textuais, propiciou resultados com baixa relevância<br>Biclustering e coclustering are data mining tasks that allow the extraction of relevant information about data and have been applied successfully in a wide variety of domains, including those involving textual data - the focus of interest of this research. In biclustering and coclustering tasks, similarity criteria are applied simultaneously to the rows and columns of the data matrices, simultaneously grouping the objects and attributes and enabling the discovery of biclusters/coclusters. However their definitions vary according to their natures and objectives, being that the task of coclustering can be seen as a generalization of the task of biclustering. These tasks applied in the textual data demand a representation in a model of vector space, which commonly leads to the generation of spaces characterized by high dimensionality and sparsity and influences the performance of many algorithms. This work provides an analysis of the behavior of the algorithm for biclustering Cheng and Church and the algorithm for coclustering non-negative block decomposition (NBVD) applied to the context of textual data. Quantitative and qualitative experimental results are shown, from experiments on synthetic datasets created with different sparsity levels and on a real data set. The results are evaluated in terms of their biclustering oriented measures, internal clustering measures applied to the projections in the lines of the biclusters/coclusters and in terms of generation of information. The analysis of the results clarifies questions related to the difficulties faced by these algorithms in the experimental environment, as well as if they are able to provide differentiated information useful to the field of text mining. In general, the analyses carried out showed that the NBVD algorithm is better suited to work with datasets in high dimensions and with high sparsity. The algorithm of Cheng and Church, although it obtained good results according to its own objectives, provided results with low relevance in the context of textual data
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Alves, Ana Carolina Araruna. "Efeitos do laser de baixa intensidade de 100 mW e 50 mW sobre osteoartrite experimental." Universidade Nove de Julho, 2012. http://bibliotecadigital.uninove.br/handle/tede/1493.
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Previous issue date: 2012-12-11<br>The cartilage damage and destruction are common in osteoarthritis (OA) and are associated with elevated levels of matrix metalloproteinases (MMPs), proteinases that can degrade all components of the extracellular matrix (ECM). The objective was to study the effect of low level laser therapy (LLLT) at 50mW and 100mW in joint damage evaluated by histopathological analysis, and protein expression of metalloproteinases (MMPs) 2 and 9 in the articular lavage. We used 60 male Wistar rats randomly divided into 4 groups of 15 animals each: a control group, an injury group, and two treated groups, one with LLLT 50mW and other with 100mW. The animals underwent OA induction (papain solution 4%) and, on the euthanasia day was collected the articular lavage, which was immediately centrifuged and the supernatant saved for analysis of protein expression by Western blot. The material was stained with hematoxylin and eosin for histopathologic description and Picrosirius Red, to estimate the percentage of collagen fibers. As a result, it was observed that both laser groups were efficient on tissue repair, decreasing the expression of collagen type III and increasing type I at all the experimental times, however, the group LLLT 50mW was better in reducing MMP - 9 in relation to the LLLT 100mW group in 21 days. In conclusion, LLLT 50 mW was more efficient on modulating matrix metalloproteinases and repair of the cartilaginous tissue.<br>A lesão da cartilagem e a sua destruição são comuns em osteoartrite (OA) e estão associadas com níveis elevados de metaloproteinases de matriz (MMPs), proteinases que podem degradar todos os componentes da matriz extracelular (ECM). O objetivo foi estudar o efeito do laser de baixa intensidade (LBI) com 50mW e 100mW em lesões articulares por meio da análise histopatológica, bem como pela expressão proteíca de metaloproteinases 2 e 9 no lavado articular. Utilizou-se 60 ratos Wistar machos, distribuídos aleatoriamente em 4 grupos de 15 animais, sendo: um grupo controle; um grupo lesão, e dois grupos tratados, um com LBI de 50mW, e outro com LBI de 100mW. Os animais foram submetidos a OA (solução de papaína a 4%) e, no dia da eutanásia, coletou-se o lavado articular, que foi imediatamente centrifugado e o sobrenadante armazenado para análise de expressão protéica por Western Blot. O material foi corado com HE para a descrição histopatológica e Picrosirius Red, para estimar o percentual de fibras colágenas. Como resultado, observou-se que os dois grupos laser foram eficientes na reparação tecidual, diminuindo a expressão de colágeno tipo III e aumentando a do tipo I em todos os tempos experimentais, no entanto, o grupo LBI 50mW foi melhor em relação à redução da metaloproteinase 9 em relação ao grupo LBPI 100mW em 21 dias. Podemos concluir que o LBI 50 mW foi mais eficiente na modulação de metaloproteinases de matriz e reparação do tecido cartilaginoso.
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Giubertoni, Silvia. "Trattamento di matrici compostabili da RU mediante biostabilizzazione controllata, presso l'impianto Nuova Geovis, di Sant'Agata Bolognese." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2010. http://amslaurea.unibo.it/1020/.
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La relazione mira ad illustrare l'importanza del compostaggio, quale tecnologia per lo smaltimento dei rifiuti e recupero di risorse. Vengono descritti il processo di stabilizzazione aerobica, i meccanismi microbici e i parametri fisico-chimici che lo caratterizzano. E' evidenziata l'importanza della raccolta differenziata e della scelta delle matrici compostabili nell'ottimizzazione di questa biotecnologia spontanea per il trattamento di rifiuti e reflui organici putrescibili. E' sottolineato, inoltre, come una corretta gestione del processo permetta di valorizzare residui di varia natura trasformandoli in un buon compost, prodotto valido dal punto di vista agronomico e ambientale.
Nella parte finale della relazione verrà inoltre descritto un impianto di compostaggio, presente nel territorio regionale, la Nuova Geovis di Sant'Agata Bolognese e dal punto di vista applicativo, verrà costruito un modello, che permetta di legare l'andamento della temperatura all'andamento dell'IRD, Indice di Respirazione Dinamico, attraverso dati raccolti presso l'impianto, relativi ovviamente a Indice di Respirazione Dinamico (IRD) e temperatura. Questo anche per valutare il corretto del processo stesso.
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Kuch, Holger [Verfasser]. "Bestimmung von Estrogenen und endokrin aktiven Phenolen aus wässrigen Matrices im 0.1 - 100 Nanogramm/Liter-Bereich / Holger Kuch." Ulm : Universität Ulm. Fakultät für Naturwissenschaften, 2001. http://d-nb.info/1015324967/34.
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Kim, Paul J. "On the 4 by 4 Irreducible Sign Pattern Matrices that Require Four Distinct Eigenvalues." Digital Archive @ GSU, 2011. http://digitalarchive.gsu.edu/math_theses/101.
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A sign pattern matrix is a matrix whose entries are from the set {+,-,0}. For a real matrix B, sgn(B) is the sign pattern matrix obtained by replacing each positive(respectively, negative, zero) entry of B by + (respectively, -, 0). For a sign pattern matrix A, the sign pattern class of A, denoted Q(A), is defined as {B: sgn(B) = A}.
An n by n sign pattern matrix A requires all distinct eigenvalues if every real matrix whose sign pattern is represented by A has n distinct eigenvalues. In this thesis, a number of sufficient and/or necessary conditions for a sign pattern to reuiqre all distinct eigenvalues are reviewed. In addition, for n=2 and 3, the n by n sign patterns that require all distinct eigenvalues are surveyed. We determine most of the 4 by 4 irreducible sign patterns that require four distinct eigenvalues.
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Brunialti, Lucas Fernandes. "Fatoração de matrizes no problema de coagrupamento com sobreposição de colunas." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/100/100131/tde-31102016-123504/.
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Coagrupamento é uma estratégia para análise de dados capaz de encontrar grupos de dados, então denominados cogrupos, que são formados considerando subconjuntos diferentes das características descritivas dos dados. Contextos de aplicação caracterizados por apresentar subjetividade, como mineração de texto, são candidatos a serem submetidos à estratégia de coagrupamento; a flexibilidade em associar textos de acordo com características parciais representa um tratamento adequado a tal subjetividade. Um método para implementação de coagrupamento capaz de lidar com esse tipo de dados é a fatoração de matrizes. Nesta dissertação de mestrado são propostas duas estratégias para coagrupamento baseadas em fatoração de matrizes não-negativas, capazes de encontrar cogrupos organizados com sobreposição de colunas em uma matriz de valores reais positivos. As estratégias são apresentadas em termos de suas definições formais e seus algoritmos para implementação. Resultados experimentais quantitativos e qualitativos são fornecidos a partir de problemas baseados em conjuntos de dados sintéticos e em conjuntos de dados reais, sendo esses últimos contextualizados na área de mineração de texto. Os resultados são analisados em termos de quantização do espaço e capacidade de reconstrução, capacidade de agrupamento utilizando as métricas índice de Rand e informação mútua normalizada e geração de informação (interpretabilidade dos modelos). Os resultados confirmam a hipótese de que as estratégias propostas são capazes de descobrir cogrupos com sobreposição de forma natural, e que tal organização de cogrupos fornece informação detalhada, e portanto de valor diferenciado, para as áreas de análise de agrupamento e mineração de texto<br>Coclustering is a data analysis strategy which is able to discover data clusters, known as coclusters. This technique allows data to be clustered based on different subsets defined by data descriptive features. Application contexts characterized by subjectivity, such as text mining, are candidates for applying coclustering strategy due to the flexibility to associate documents according to partial features. The coclustering method can be implemented by means of matrix factorization, which is suitable to handle this type of data. In this thesis two strategies are proposed in non-negative matrix factorization for coclustering. These strategies are able to find column overlapping coclusters in a given dataset of positive data and are presented in terms of their formal definitions as well as their algorithms\' implementation. Quantitative and qualitative experimental results are presented through applying synthetic datasets and real datasets contextualized in text mining. This is accomplished by analyzing them in terms of space quantization, clustering capabilities and generated information (interpretability of models). The well known external metrics Rand index and normalized mutual information are used to achieve the analysis of clustering capabilities. Results confirm the hypothesis that the proposed strategies are able to discover overlapping coclusters naturally. Moreover, these coclusters produced by the new algorithms provide detailed information and are thus valuable for future research in cluster analysis and text mining
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Müller, Werner, and Andrej Pazman. "Design Measures and Extended Information Matrices for Optimal Designs when the Observations are Correlated." Department of Statistics and Mathematics, WU Vienna University of Economics and Business, 1995. http://epub.wu.ac.at/1030/1/document.pdf.
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COELHO, Pedro Cézar Pereira. "Modelo insumo-produto nas relações intersetoriais de água no brasil." Universidade Federal de Campina Grande, 2016. http://dspace.sti.ufcg.edu.br:8080/jspui/handle/riufcg/1009.
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Previous issue date: 2016<br>O modelo insumo-produto é uma teoria amplamente utilizada na economia que ao longo das últimas duas décadas teve sua aplicação estendida a diversas áreas do conhecimento. Nos últimos dez anos alguns pesquisadores usaram esse conceito para mensurar as relações econômicas associadas a demanda de água para setores da economia em cidades com características de escassez de recursos hídricos. Neste trabalho foram mensuradas algumas relações de consumo direto e indireto de água dos setores agropecuário, industrial, comercial e público a nível municipal, estadual e nacional. Na região abastecida pela Barragem Epitácio Pessoa os setores agropecuário e comercial apresentaram elevados percentuais de consumo direto de água, da ordem de 88% e 71%, respectivamente, enquanto o industrial apresentou percentual de 97% de consumo indireto em relação ao total de consumo. Para cada um metro cúbico de aumento de demanda de água, o setor industrial provoca um consumo adicional no agropecuário de 27 m3. No estado da Paraíba para cada aumento de um metro cúbico de água no setor industrial provoca aumento no setor agropecuário de 8 m3. O setor agropecuário apresentou para todos os Estados da federação elevado consumo direto de água, sendo a região Nordeste, a maior consumidora, com 35% do total, enquanto o maior consumo de água na forma virtual (consumo indireto) no Brasil encontra-se no setor industrial. No setor industrial, cada metro cúbico consumido diretamente provoca, no mesmo, a nível nacional um consumo médio adicional de água de 2 m3 e no setor agropecuário de 9 m3.<br>The input-output model is a theory widely used in the economy over the past two decades which has been applied to various areas of knowledge. Some researchers have used this concept to measure the economic relations associated with water demand for economy areas in with shortages of fresh water. In this work we have measured water relationship (direct and indirect form) from agricultural, industrial, commercial and public sectors for municipal, state and national levels in Brazil. In the Epitácio Pessoa Dan, the agricultural and commercial sectors showed a high percentage of direct water use of 88% and 71%, respectively, while the industrial sector is 97% as indirect consumption. For each one cubic meter increase of water demand, the industrial sector causes an additional water consumption in the agricultural sector of 27 m3. In the state of Paraíba, for each one cubic meter of water increase the industrial sector leads to an increase in agricultural sector of 8 m3. The agricultural sector showed high direct water consumption in all states of Brazil. The Northeast region is the largest water consumer with 35% of the total, while the highest water consumption in virtual form (indirect consumption) in Brazil is the industrial sector. In the industrial sector, for each one cubic meter consumed directly causes an additional national water consumption of 2 m3 while for the agricultural sector is 9 m3.
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Reale, Fábio Tosetto. "Métodos de Monte Carlo para amostragem de permutações com restrições e aplicações." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/100/100132/tde-06092018-144335/.
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Neste trabalho definimos o processo de exclusão simples simétrico em tempo discreto sobre grafos por meio de permutações com restrições sobre os índices dos vértices dos grafos. O processo é uma generalização das permutações dos índices do grafo completo. Apresentamos algoritmos de Monte Carlo e de amostragem sequencial por importância para amostrar permutações com restrições inspirados pelo problema análogo de calcular permanentes. Como aplicação, utilizamos esses algoritmos para estimar os tempos de relaxação do processo de exclusão simples simétrico em tempo discreto sobre grafos aleatórios densos de Erdös-Rényi com laços<br>In this work we define the symmetric simple exclusion process in discrete time over graphs by means of suitably restricted permutations over the labels of the vertices of the graphs. The process is a generalization of the shuffling of labels on the complete graph. Straightforward Monte Carlo and sequential importance sampling algorithms to sample restricted permutations inspired by the related problem of computing permanents are discussed. We illustrate the formalism by estimating the relaxation times of the symmetric simple exclusion process in discrete time over dense loop-augmented Erdös-Rényi random graphs
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Bolton, Clement II. "MMP-7 is Required for TGF-β and EGF Induced Migration and Invasion in Prostate Cancer Cells". DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 2018. http://digitalcommons.auctr.edu/cauetds/150.
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Prostate cancer micrometastasis allows cancer cells to vacate their original tumor sites and migrate to distant parts of the body via the bloodstream, lymphatic system, or by direct extension. Cells synthesize and secrete matrix metalloproteinases (MMPs) that degrade proteins of the surrounding extracellular matrix (ECM); thus allowing them to escape into the lymphatic or circulatory systems to invade other tissues. Transforming growth factor β (TGF-β) induces the migration and invasion of cancer cells and the expression of matrix metalloproteinases (MMPs), specifically MMP-2, and -9 in several malignancies. In this study, we examined the role of MMP-7, a known activator of MMP-2 and MMP-9, in TGF-β signaling in cell proliferation, migration, and invasion in prostate cancer cells. Basal expression levels of MMP7 mRNA, protein, and secreted protein were determined using RT-PCR, western blot analysis, and ELISA, respectively. Our data show that MMP7 mRNA and proteins were differentially expressed in several cell line models representing different stages of prostate cancer. TGF-β1 induces MMP-7 gene expression and protein levels 24 and 48 hours after treatment in PC3 cells. Our data also show that TGF-β induces cell migration and invasion in PC3 and E006AA cells; however, the selective knockdown of MMP7 expression using siRNA resulted in a significant decrease in control and TGFβ-induced cell migration and invasion in both PC3 and E006AA cells. MMP-7 knockdown also caused significant reduction in cell proliferation in PC3 cells. Our data suggest that MMP7 is essential for cell migration and invasion in prostate cancer cells indicating that it may be required for TGFβ-induced cancer metastases.
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Wang, Peng. "IMPEDANCE-TO-SCATTERING MATRIX METHOD FOR LARGE SILENCER ANALYSIS." UKnowledge, 2017. https://uknowledge.uky.edu/me_etds/102.
Full textAbstract:
Large silencers used in the power generation industry usually have a very large cross section at the inlet and outlet. Higher-order modes will populate the inlet and outlet even at very low frequencies. Although the silencer itself is often modeled by a three-dimensional analysis tool such as the boundary element method (BEM) or finite element method (FEM), a direct computation of the transmission loss (TL) from the BEM or FEM model can be challenging without incorporating certain forms of modal expansion.
A so-called “impedance-to-scattering matrix method” is proposed to extract the modes at the inlet and outlet from the BEM impedance matrix based on the point collocation method. The BEM impedance matrix relates the sound pressures at the inlet and outlet to the corresponding particle velocities, while the scattering matrix relates the modes at the inlet and outlet. Normally there are more boundary elements than the total number of modes at the inlet and outlet, and a least-squares procedure is used to condense the element-based impedance matrix to the mode-based scattering matrix. The TL computation will follow if a certain form of the incident wave is assumed and the outlet is non-reflective. Several commonly used inlet/outlet configurations are considered in this dissertation, which include axisymmetric, non-axisymmetric circular, and rectangular inlet/outlet shapes. In addition to the single inlet and outlet silencers, large multi-inlet and multi-outlet silencers are also investigated.
Besides the collocation-based impedance-to-scattering matrix method, an integral-based impedance-to-scattering matrix method based on the reciprocal identity is also proposed for large silencer analysis. Although it may be more time-consuming to perform the additional numerical integration, an integral-based method is free of any uncertainties associated with collocation points. The computational efficiency, accuracy and stability are compared between two proposed methods.
One bonus effect of producing the scattering matrix is that it can also be used to combine subsystems in series connection. The Redheffer’s star product is introduced to combine scattering matrices of subsystems.
In the design stage, rapid assessment of the silencer performance is always preferred. However, the existing analytical approaches are only suitable for simple dissipative silencers such as straight lined ducts. A two-dimensional first-mode semi-analytical solution is developed to quickly evaluate the performance of tuned dissipative silencers below the cut-off frequency. The semi-analytical solution can also serve as a validation tool for the BEM.
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Moraes, Andréa Kochhann Machado de. "DESENVOLVIMENTO CURRICULAR DO CURSO DE PEDAGOGIA DA UEG (2000-2010)." Pontifícia Universidade Católica de Goiás, 2013. http://localhost:8080/tede/handle/tede/1100.
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Previous issue date: 2013-09-16<br>The curriculum of Pedagogy Graduation Course of three University Unit (UnU), at the Goiàs
State University is the object of this research in the Research Line PUC Goiás State, Political
and Educational Institutions. The main objective is to analyze the curriculum of the
Education Course of UEG in Anápolis (UnUCSEH), São Luís de Montes Belos, based on
national curriculum (Diretrizes Curriculares Nacionais) and it is before and after the
unification curriculum, from from 2000 to 2010. The theoreis used as fundamentation to this
research are: a) conceptualization of curriculum studies and theories of curriculum based
mainly on studies of Goodson (1995), Pacheco (1996) and Sacristan (2008), b) studies on the
essential elements of the Political pedagogical course at the University, specifically
referenced in Veiga (1995, 1998), Cavagnari (1998) and in legal documents as PDI (2010)
and PPI (2011) c ) historicizing of pedagogy in Brazil Goias and UEG having as theoretical
contributions Brzezinski (1987, 1996, 2011a, 2011c) and Silva (2006), d) of the National
Curriculum Guideline of Pedagogy. And based on the analysis of documents from the
National Council of Education (Conselho Nacional da Educação). The problem of research
includes studies and analyzes of curriculum development of the Education Course at UEG
before and after the unification of curriculum based on legal documents, so the problem is
stated thus: " What are the strong and weak aspects resulting of the process and development
of the unification of the curriculum in Pedagogy Course of UEG in Anápolis UnUs
(UnUCSEH), São Luís de Montes Belos documents?". The choice of method was the
dialectical historical materialism because it is the most suitable for qualitative research in
education. The methodology is based on qualitative approach, with multiple case study
whichwas developed through documentary analysis, observation during the visit of three
Colleges UnUs, informal conversations called spontaneous reports and analysis of a
questionnaire. The purpose of the sample of the three Unus was selected according to criteria
established a priori. The subjects are 28 teachers who answered the questionnaires. In
informal conversations or spontaneous reports two secretaries of the University, a coordinator
and six teachers. The results we had states that the potential unification curriculum is
effective in Pedagogy courses investigated so relaxed, since: a) the uniqueness in the
curriculum is represented by a common base b) the flexibility is expressed in several parts
that consider the regional aspect and the interest of the students c) proclaimed in PPC the
general principle that teaching practice is the object of Pedagogy d) articulated to guiding
principles: such as the research and training as a cognitive principle, the integration of theory
and practice, ie , praxis and flexibility. Several weak aspects were diagnosed and summarized
in: a) inconsistencies in PPC b) disinterest about the PPC c) lack of study groups, d) lack of
procurement, e) lack continuing education, f) little research, extension and monitoring; g)
short interdisciplinary practice; h) misunderstanding of PBO i) little regency of supervision
during the trainee process j) rare regional surveys l) neglect of AEA , m) interdisciplinary
misunderstanding n) lack of knowledge and legal documents o) timid conception of identity
educator.<br>O currículo do Curso de Pedagogia de três Unidades Universitárias (UnU) da Universidade
Estadual de Goiás é o objeto desta pesquisa na Linha de Pesquisa da PUC Goiás: Estado,
Políticas e Instituições Educacionais. O objetivo geral consiste em analisar o currículo do
Curso de Pedagogia da UEG, nas UnUs de Anápolis (UnUCSEH), Campos Belos e São Luís
de Montes Belos, com base nas diretrizes curriculares nacionais vigentes, antes e depois da
unificação curricular, no período de 2000 a 2010. Os eixos norteadores do referencial teórico
são: a) conceituação de currículo e estudos sobre teorias de currículo com base sobretudo em
estudos de Goodson (1995), Pacheco (1996) e Sacristán (2008); b) estudos acerca dos
elementos essenciais do Projeto Político Pedagógico de Curso na Universidade, referenciados
especialmente em Veiga (1995, 1998), Cavagnari (1998) e nos documentos legais como PDI
(2010) e PPI (2011); c) historicização do curso de Pedagogia no Brasil, em Goiás e na UEG
tendo como aportes teóricos Brzezinski (1987, 1996, 2011a, 2011c) e Silva (2006); d)
Diretrizes Curriculares Nacionais da Licenciatura em Pedagogia, com base na análise de
documentos do Conselho Nacional de Educação. O problema da investigação abrange
estudos e análises acerca do desenvolvimento curricular do Curso de Pedagogia da UEG,
antes e após a unificação da matriz curricular com base nos documentos legais, portanto, o
problema é assim enunciado: Que fragilidades e potencialidades decorrem do processo e
desenvolvimento da unificação curricular no Curso de Pedagogia da UEG, nas UnUs de
Anápolis (UnUCSEH), Campos Belos e São Luís de Montes Belos com base nos documentos
legais? . A escolha do método materialismo histórico dialético ocorreu pelo fato de ser o
mais propício para pesquisas qualitativas no campo da educação. A metodologia de
abordagem qualitativa, com estudo de casos múltiplos, foi desenvolvida por meio de análise
documental, observação de reuniões em Colegiados do Curso das três UnUs, conversas
informais denominadas relatos espontâneos e análise de questionário. A amostra intencional
composta de três UnUs foi selecionada conforme critérios estabelecidos a priori. Os sujeitos
pesquisados são 28 professores respondentes de questionários. Nas conversas informais ou
relatos espontâneos participaram duas secretárias acadêmicas, um gestor e seis professores.
Os resultados de potencialidades alcançados foram que a unificação curricular está efetivada
nos Cursos de Pedagogia investigados de maneira flexibilizada, visto que: a) a unicidade na
matriz curricular é representada por uma base comum; b) a flexibilização se expressa na parte
diversificada que visa atender a regionalização e o interesse do alunado; c) proclamado no
PPC o princípio geral de que a prática pedagógica é o objeto da Pedagogia; d) articulado os
princípios norteadores: a pesquisa como princípio cognitivo e formativo, a integração entre
teoria e prática, ou seja, a práxis e a flexibilização. Várias fragilidades foram diagnosticadas
sintetizadas em: a) incoerências no PPC; b) desinteresse do conhecimento do currículo pelos
sujeitos do PPC c) falta de grupos de estudos; d) falta de concursos públicos; e) falta
formação continuada; f) pouca pesquisa, extensão e monitoria; g) tímida prática
interdisciplinar; h) incompreensão do PBO; i) pouca regência do estágio supervisionado; j)
raras pesquisas regionais; l) descuido das AEA; m) incompreensão interdisciplinar; n) falta
conhecimento dos Documentos legais e o) tímida concepção da identidade do pedagogo.
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Bertoluci, Cristiane Eloisa. "Proposta de método para desenvolvimento de produtos de moda a partir de técnicas manuais e resíduos de malharia circular de algodão." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/100/100133/tde-28112018-221958/.
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Em contrapartida ao fast fashion está o slow fashion, uma busca pela retomada dos meios de produção da cadeia têxtil, da valorização das técnicas tradicionais de criação e desenvolvimento e da desasceleração do consumo. Parte deste movimento incentiva a volta ao aprendizado de técnicas manuais de tecimento, como, por exemplo, o tricô, o crochê, a costura em máquinas domésticas, o tear e até a fiação. O presente trabalho tem como objetivo investigar e experimentar soluções ambientalmente sustentáveis para resíduos de malharia circular de algodão, utilizando técnicas manuais de tecimento, como o tricô e a matriz morfológica de Zwicky para desenvolver novos produtos de moda. Como matérias-primas principais foram utilizados resíduos de malha de três fontes: compra de novelos de produtores que trabalham diretamente com empresas que descartam as oréolas de malhas circulares; tecidos defeituosos descartados por empresas; peças descartadas por consumidores. A proposta para o desenvolvimento de novos produtos a partir de reuso de materiais, utilizou os seguintes métodos: o brainstorming, a matriz morfológica e o método de Pugh. Para a elaboração desse trabalho, foi feito um estudo bibliográfico da cadeira têxtil para compreender em quais momentos são gerados resíduos de malharia circular e como eles podem ser aproveitados para a elaboração do experimento deste estudo. Para direcionar ao ambientalmente sustentável, conceitos de sustentabilidade aplicados ao design e à moda, assim como conceitos de reciclagem, também foram estudados. A visão sobre técnicas manuais de tecimento e como estão inseridas no contexto atual de criatividade foi subsídio teórico para justificar a utilização do tricô para a experimentação e criação de peças de vestuário e acessórios. A geração de uma matriz morfológica de Fritz Zwicky foi a base metodológica para desenvolver novos produtos. O peso da matéria-prima resultou em produtos pesados para o uso em vestuário, mas aceitáveis para acessórios<br>Slow fashion opposes fast fashion as a search of reassuming the fashion productions means, valuing traditional handcrafts and slowing down consuming. This work aims to investigate and experiment environmentally sustainable solutions for circular knit waste, using handmade techniques like knitting and Zwickys morphological chart to develop new creative fashion garments. The works starts with a bibliographic study research on textile chain to understand in what circumstances the development of circular knit generates waste and how it can be used for this experiment. To base the study on environmentally sustainable solutions, a base study on fashion and design sustainability concept, as well as recycling, was also made. Handmade textiles, like knitting, and the creative view of handcrafts nowadays were also studied to justify it as a creative mean of experimentation for garments and accessories. Zwickys morphological chart generation was the methodological mean of developing new products. The use of circular knit waste to develop new products resulted in heavy garments, but it was well seen as a new yarn for handmade accessories
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Alevizos, Konstantinos. "Le concept de matrice dans L'Art de la Fugue de Johann Sebastian Bach." Thesis, Paris 4, 2016. http://www.theses.fr/2016PA040033.
Full textAbstract:
La thèse veut démontrer que toutes les compositions contenues dans L'Art de la Fugue possèdent entre elles des liaisons strictes et essentielles qui vont au-delà de la simple coprésence et/ou élaboration du même sujet, en créant une unité et une progression de la complexité technique dans son évolution. À travers une analyse détaillée de toutes les fugues sur trois niveaux: rythmique, harmonique et morphologique, notre objectif est d’identifier et de cataloguer tous les éléments spécifiques qui créent cette unité, afin d'arriver à la présentation du système des techniques compositionnelles utilisées par le compositeur. Nous proposons des nouveaux outils analytiques pour la compréhension des problématiques majeures liées à l’œuvre, l’ordonnancement du recueil et sa destination instrumentale<br>The thesis aims to demonstrate that all the compositions contained in the “Art of Fugue” are bound together by a pattern of tight and essential connections, which go beyond an unstructured co-existence or a simple elaboration of a common subject: they form one unit and are ordered in a sequence of increasing technical complexity.The author makes a detailed analysis of all Fugues at three levels, Rhythm, Harmony and Morphology; he identifies and classifies all elements that create the unit: he presents the method and suite of techniques employed by the composer; finally, he proposes new analytical tools for the comprehension of the main issues related
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Rocha, Jeanderson. "Um estudo comparativo entre a aderência das matrizes curriculares adotadas pelas IES da capital paulista com a proposta da ONU/UNCTAD/ISAR E MEC/CFC." Pontifícia Universidade Católica de São Paulo, 2012. https://tede2.pucsp.br/handle/handle/1500.
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Previous issue date: 2012-06-27<br>Considering accounting as an applied social science, it seems quite natural that the evolution of the society, its ways of organization, its practices, including the commercial ones, as well as the invention of new technological devices and new business models, that influence the constitution of the set of knowledge necessary to the accounting professional for the proper exercise of their profession. It has been a growing perception that the market expects the accountants to be interdisciplinary agents, with holistic training, with the ability to deal with numbers and computers, which are endowed with logical reasoning and analytical, being capable of making decisions and that know how to communicate yourself efficiently. In this context, the College Institutions develop a prominent role, and must offer to their students an adequate education according to the market needs, each time more demanding and globalized. In this sense, the basic curriculum of accounting science course over the years has undergone to reformulation, where the technical and quantitative nature of the profession has been complemented with disciplines aimed at training more humanistic accountants, in order to efficiently enable them to interact and communicate with the various users of information. This work discuss about the importance of curriculum to the process of accountant formation and to the college degree in general. And finally, from the premisses issued by the UN-UNCTAD noted whether the accounting science courses that are offered in the city of Sao Paulo are appropriate to market needs, as well as the degree of adherence of the curricula of colleges of the state capital the model recommended by the UN<br>Sendo a contabilidade uma ciência social aplicada, parece bastante natural que a evolução da sociedade, de suas formas de organização, de suas práticas, inclusive comerciais, bem como a invenção de novos aparatos tecnológicos e novos modelos de negócios, influencie a constituição do conjunto de saberes necessários ao profissional da contabilidade para o adequado exercício de sua profissão. Tem sido cada vez maior a percepção de que o mercado espera que os contadores sejam agentes interdisciplinares, com formação holística, com habilidade para lidar com números e informática, que sejam dotados de raciocínio lógico e analítico, que tenham a capacidade de tomar decisões e que saibam comunicar-se eficientemente. Neste contexto, as Instituições de Ensino Superior IES desenvolvem um papel proeminente, devendo oferecer aos seus alunos uma formação adequada às necessidades do mercado, cada vez mais exigente e globalizado. Nesse sentido, o currículo básico do curso de ciências contábeis ao longo dos anos vem sofrendo reformulações, onde o caráter tecnicista e quantitativo da profissão tem sido complementado com disciplinas que visam uma formação mais humanista do contador, com vistas a habilitá-lo a uma interação e comunicação mais eficiente com os diversos usuários da informação. Assim, este trabalho disserta sobre a importância do Currículo no processo de formação do contador e no ensino superior em linhas gerais. E por fim, a partir das premissas emanadas pela ONU-UNCTAD, verificou-se se os cursos de ciências contábeis que são oferecidos na cidade de São Paulo estão adequados às necessidades do mercado, bem como o grau de aderência dos currículos das faculdades da capital paulista ao modelo preconizado pela ONU
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Panthi, Kamalesh. "A Methodological Framework for Modeling Pavement Maintenance Costs for Projects with Performance-based Contracts." FIU Digital Commons, 2009. http://digitalcommons.fiu.edu/etd/120.
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Performance-based maintenance contracts differ significantly from material and method-based contracts that have been traditionally used to maintain roads. Road agencies around the world have moved towards a performance-based contract approach because it offers several advantages like cost saving, better budgeting certainty, better customer satisfaction with better road services and conditions. Payments for the maintenance of road are explicitly linked to the contractor successfully meeting certain clearly defined minimum performance indicators in these contracts. Quantitative evaluation of the cost of performance-based contracts has several difficulties due to the complexity of the pavement deterioration process. Based on a probabilistic analysis of failures of achieving multiple performance criteria over the length of the contract period, an effort has been made to develop a model that is capable of estimating the cost of these performance-based contracts. One of the essential functions of such model is to predict performance of the pavement as accurately as possible. Prediction of future degradation of pavement is done using Markov Chain Process, which requires estimating transition probabilities from previous deterioration rate for similar pavements. Transition probabilities were derived using historical pavement condition rating data, both for predicting pavement deterioration when there is no maintenance, and for predicting pavement improvement when maintenance activities are performed. A methodological framework has been developed to estimate the cost of maintaining road based on multiple performance criteria such as crack, rut and, roughness. The application of the developed model has been demonstrated via a real case study of Miami Dade Expressways (MDX) using pavement condition rating data from Florida Department of Transportation (FDOT) for a typical performance-based asphalt pavement maintenance contract. Results indicated that the pavement performance model developed could predict the pavement deterioration quite accurately. Sensitivity analysis performed shows that the model is very responsive to even slight changes in pavement deterioration rate and performance constraints. It is expected that the use of this model will assist the highway agencies and contractors in arriving at a fair contract value for executing long term performance-based pavement maintenance works.
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Ruan, Kangping. "NUMERICAL AND EXPERIMENTAL TECHNIQUES FOR ASSESSING THE ACOUSTIC PERFORMANCE OF DUCT SYSTEMS ABOVE THE PLANE WAVE CUTOFF FREQUENCY." UKnowledge, 2018. https://uknowledge.uky.edu/me_etds/120.
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This research deals with determining the acoustic attenuation of heating, ventilation, and air conditioning (HVAC) ductwork. A finite element approach was developed for calculating insertion loss and breakout transmission loss. Procedures for simulating the source and receiving rooms were developed and the effect of structureborne flanking was included. Simulation results have been compared with measurements from the literature and the agreement is very good. With a good model in place, the work was extended in three ways. 1) Since measurements on full-scale equipment are difficult, scale modeling rules were developed and validated. 2) Two different numerical approaches were developed for evaluating the transmission loss of silencers taking into account the effect of higher order modes. 3) A power transfer matrix approach was developed to assess the acoustic performance of several duct components connected in series.
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Arthur, Jacob D. "Enhanced Prediction of Network Attacks Using Incomplete Data." NSUWorks, 2017. http://nsuworks.nova.edu/gscis_etd/1020.
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For years, intrusion detection has been considered a key component of many organizations’ network defense capabilities. Although a number of approaches to intrusion detection have been tried, few have been capable of providing security personnel responsible for the protection of a network with sufficient information to make adjustments and respond to attacks in real-time. Because intrusion detection systems rarely have complete information, false negatives and false positives are extremely common, and thus valuable resources are wasted responding to irrelevant events. In order to provide better actionable information for security personnel, a mechanism for quantifying the confidence level in predictions is needed. This work presents an approach which seeks to combine a primary prediction model with a novel secondary confidence level model which provides a measurement of the confidence in a given attack prediction being made. The ability to accurately identify an attack and quantify the confidence level in the prediction could serve as the basis for a new generation of intrusion detection devices, devices that provide earlier and better alerts for administrators and allow more proactive response to events as they are occurring.
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Zhebel, Elena. "A multigrid method with matrix-dependent transfer operators for 3D diffusion problems with jump coefficients." Doctoral thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2009. http://nbn-resolving.de/urn:nbn:de:bsz:105-682918.
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Gegeben sei ein lineares Gleichungssystem $Au = f$ mit Koeffizientenmatrix $A$, welche eine spezielle block-tridiagonale Struktur besitzt. Solche lineare Gleichungssysteme entstehen bei der Diskretisierung dreidimensionaler elliptischer Randwertprobleme mit 7- oder 27-Punkte-Stern. In geophysikalischen Anwedungen, insbesondere bei Aufgaben aus der Geoelektrik, haben die Randwertprobleme unstetige Koeffizienten und sind meistens auf nicht-uniformen Gittern diskretisiert. Klassische geometrische Mehrgitterverfahren konvergieren um so langsamer, je stärker die Koeffizientensprünge ausfallen. Außerdem kann die Konvergenz durch die Variation der Gitterabstände beeinträchtigt werden. Zur Lösung wird ein matrix-abhängiges Mehrgitterverfahren vorgestellt. Als Glätter wird eine unvollständige Block LU-Zerlegung verwendet. Die Gittertransferoperationen werden anhand der Einträge der Matrix $A$ ermittelt. Das resultierende Verfahren erweist sich als sehr robust, insbesondere wenn es als Vorkonditionierung für das Verfahren der konjugierten Gradienten eingesetzt wird.
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Neto, Emilio Murcia. "Contratos por disponibilidade de usinas termelétricas: uma análise dos resultados econômicos de operação." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/106/106131/tde-13072016-103610/.
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Esta dissertação busca analisar a eficiência econômica da forma de classificação das usinas geradoras nos leilões de contratação de energia elétrica por disponibilidade. Historicamente, o Brasil tem apresentado uma matriz de geração de energia elétrica predominantemente hídrica, que, embora mais econômica do que as matrizes de geração prevalentemente térmicas, pode resultar em déficits de geração em períodos de escassez hidrológica. O ano de 2001 evidenciou tal perigo. Nele, uma série de baixas afluências hidrológicas, sem o prévio incremento adequado do parque gerador, resultou no Programa de Redução do Consumo e, através desse, num decréscimo de 20% na demanda por energia elétrica à época, acentuando a preocupação pela incorporação de empreendimentos termelétricos para diversificar a matriz de geração do País. Entre as modificações realizadas, destaca-se a alteração da estrutura de comercialização de energia elétrica no Brasil visando a favorecer à expansão da oferta termelétrica, concebendo-se a modalidade de contratação por disponibilidade. Tal modalidade transfere o risco da operação e do preço do combustível dos ombros do gerador para os do consumidor. Contudo, fez-se necessário, para viabilizar tal modalidade de contratação, o uso de ferramental diferenciado para classificação dessa nova oferta de energia nos leilões, e a ferramenta adotada foi o Índice de Custo Benefício (ICB). Nesse contexto, o objetivo deste trabalho é analisar os resultados econômicos decorrentes do uso do ICB na contratação de usinas termelétricas por disponibilidade, verificando se ele se mostrou ou não adequado a tal fim. Para isso, analisam-se os resultados dos leilões para a contratação da energia de novos empreendimentos, destacando a participação de cada fonte energia e os valores financeiros exercidos por meio dos preços, das receitas fixas e dos respectivos ICBs. Além disso, é feita uma análise das operações das usinas termelétricas após a contratação. Dessa forma, são utilizados os anos operativos de 2014 e 2015, nos quais foi registrada uma profunda escassez hidrológica, como base na comparação de cenários de geração de energia elétrica com diferentes participações entre empreendimentos termelétricos a óleos derivados do petróleo e a gás natural. Os cenários utilizados são quatro: dois com composição real entre as dessas duas fontes termelétricas (óleos derivados do petróleo e a gás natural) para os anos de 2014 e 2015; e dois simulados, com 100% da geração termelétrica sendo realizada apenas a gás natural para os mesmos anos. Os resultados financeiros encontrados indicam que a potencial economia no custo da energia elétrica gerada no cenário simulado comparado ao cenário real seria da ordem de 6 bilhões de reais nos anos de 2014 e 2015. Assim, considerando as 59 usinas que integraram o universo da análise, o resultado que indica ineficiência no uso ICB, o qual apontou vantagem econômica de certos empreendimentos no momento de suas contratações que não se concretizaram nos cenários testados de baixa hidrologia. Ademais, fica clara a necessidade de aprimorar a metodologia de classificação de empreendimentos de geração de modo que tal metodologia leve em conta os efeitos de eventuais anos de baixa hidrologia, buscando tornar a contratação de energia elétrica no Brasil mais econômica e mais aderente à volatilidade hidrológica do País.<br>This thesis seeks to analyze the economic efficiency of the classification method for power plants in power availability contracts. Historically Brazil has presented a predominantly hydroelectric power generation matrix, which, though more economical than predominantly thermal generation matrix, can result in the generation deficits in hydrological scarcity periods. The year 2001 showed such danger. In it a number of low hydrological inflows, without adequate prior increase in generating capacity, resulted in rationing of 20% in demand for electricity at the time, stressing the concern by incorporating thermal power projects to diversify the country generation matrix. Among the changes made, it altered the electricity market structure in Brazil in order to favor the expansion of the thermoelectric supply, creating the availability contracts modality. This mode transfers the risk of the operation and the price of fuel from generator to the consumer. However, it was necessary to enable this type of contract, the use of different tools for classification in the auctions, and the tool adopted was the Cost Benefit Index (CBI). The objective of this study is to analyze the economic results from the use of CBI in hiring thermoelectric plants using availability contracts, checking if was or not suitable for this purpose. In this sense, we analyze the results of the auctions for new energy projects, highlighting the contribution of each energy source and the financial figures exercised through prices, the fixed income and ICBS. Moreover, it is also made an analysis of the operations of power plants after hiring. Thus, operating years used were 2014 and 2015, in which it was registered a profound hydrological shortage, based on the comparison of electricity generation scenarios with different interests between thermal power projects to petroleum oils and natural gas. The scenarios used were four: two with real composition between these two thermal sources for the years 2014 and 2015, petroleum oils and natural gas; and two simulated, with 100% of thermal generation with natural gas for the same years. The financial results indicate that the potential savings in the cost of the electricity generated in the simulated scenario compared to the real scenario would be around 6,1 billion reais in the years 2014 and 2015. Thus, considering the 59 plants that integrated the universe of analysis, the result indicates the inefficiency of the use ICB, which pointed out the economic advantage contracts that were not hired in low hydrology scenario tested. In addition, it is a clear the need to improve the classification methodology for generation projects in a way that takes into account the effects low hydrology year, trying to make the electricity contracts more economical to Brazil and more adherent to hydrological volatility of the country.
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Langer, Markus E., Aloisia Schön, Michaela Egger-Steiner, and Irmgard Hubauer. "Implementing evaluation in the context of sustainable development (II). The strategic orientation in the context of evaluations with sustainable development as part of a Tool Box." Forschungsschwerpunkt Nachhaltigkeit und Umweltmanagement, WU Vienna University of Economics and Business, 2003. http://epub.wu.ac.at/104/1/document.pdf.
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In the context of sustainable development, evaluations have particularly high relevance as complex issues have to be dealt with generally over an extended period of time. Furthermore, there is a growing demand to evaluate against the concept of sustainable development. Especially evaluations with sustainable development are a rather new type of evaluation, as the source of its evaluation questions and the criteria applied are rooted in the concept of sustainable development. Sustainability of a specific project or process is often highly case specific as sustainable development is determined by many often unique issues. However, evaluations would be highly inefficient, if they would have to be newly designed in every case. Thus it is necessary to determine and utilize the major issues for evaluations with sustainable development. This paper is part of a series of three papers - which can be used independently - that present the major common issues for evaluations with sustainable development in a Tool Box. The results presented here are based on outcomes of a research project funded by the "Austrian Science Fund". This paper includes the "strategic orientation tool", which was developed as a tool for reflection and decision upon the general outline of an evaluation with sustainable development. It helps to define a design- frame with respect to its information-focus, scope and utilization. The core of the tool is a matrix that is based on two key- functions. On the one hand it defines which contents should be assessed: "What is the object of evaluation?". On the other hand it is oriented along the actual utilization of the evaluation: "How the gained results of the evaluation should be communicated and to whom?". (author's abstract)<br>Series: Research Paper Series of the Research Focus Managing Sustainability
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Diab, Duranton Salam. "Phonétique et sémantique dans le lexique de l'arabe : le "'Ibdal" dans la tradition grammaticale arabe, l'étude de la matrice {[coronal], [dorsal]}." Lyon, Ecole normale supérieure, 2009. http://www.theses.fr/2009ENSF0061.
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The thesis comprises two main parts : one historical and the other theoretical. The first part is a study of the ’ibdāl in which several salient works are analysed. Four Arab scholars whose works are the most important in the area under consideration are studied : Ibn al-Sikkīt, Al-Zajjājī, Abū al-Ṭayyib al-Luġawī and Ibn Jinnī. We examine the way in which, within the framework of the Arabic grammatical tradition, the lexicographers and grammarians have apprehended the phonetic and semantic similarities present in the Arabic lexicon and which are referred to by the name : ’ibdāl. The second part is a contribution to the theory of matrices and etymons (TME) elaborated by G. Bohas. We apply TME to the study of the {[coronal], [dorsal]} matrix which has a substantial lexical corpus. We endeavour to demonstrate that meaning is organized around a matrix of features (a macro-significant) associated with a macro-signifié. We also examine the polysemic, homonymic or enantiosemic relationships which are present within the same lexical heading, establishing the typology of these semantic combinations arising from the crossing of etymons<br>La thèse s’articule en deux grandes parties : une historique et l’autre théorique. La première propose une étude du ’ibdāl par l’analyse de quelques ouvrages repères. Quatre savants arabes y sont étudiés : Ibn al-Sikkīt, Al-Zajjājī, Abū al-Ṭayyib al-Luġawī et Ibn Jinnī dont les œuvres sont les plus importantes dans le domaine concerné. Nous y examinons la manière dont les lexicographes et grammairiens ont, dans le cadre de la tradition grammaticale arabe, appréhendé les similitudes phonétiques et sémantiques présentes dans le lexique de l’arabe et désignées sous le nom de : ’ibdāl. La seconde partie se veut une contribution à la théorie des matrices et étymons (TME) élaborée par Bohas. Notre contribution consiste dans l’étude de la matrice {[coronal], [dorsal]} qui présente un corpus lexical conséquent. Nous nous attachons à montrer que le sens s’articule en une matrice de traits (macro-signifiant) associée à un macro-signifié. Nous étudions également les relations de polysémie, d’homonymie ou d’énantiosémie présentes au sein d’une même entrée lexicale, en établissant la typologie de ces combinaisons sémantiques issues du croisement des étymons
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Zemkoho, Alain B. "Bilevel programming." Doctoral thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2012. http://nbn-resolving.de/urn:nbn:de:bsz:105-qucosa-89017.
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We have considered the bilevel programming problem in the case where the lower-level problem admits more than one optimal solution. It is well-known in the literature that in such a situation, the problem is ill-posed from the view point of scalar objective optimization. Thus the optimistic and pessimistic approaches have been suggested earlier in the literature to deal with it in this case. In the thesis, we have developed a unified approach to derive necessary optimality conditions for both the optimistic and pessimistic bilevel programs, which is based on advanced tools from variational analysis. We have obtained various constraint qualifications and stationarity conditions depending on some constructive representations of the solution set-valued mapping of the follower’s problem. In the auxiliary developments, we have provided rules for the generalized differentiation and robust Lipschitzian properties for the lower-level solution setvalued map, which are of a fundamental interest for other areas of nonlinear and nonsmooth optimization.
Some of the results of the aforementioned theory have then been applied to derive stationarity conditions for some well-known transportation problems having the bilevel structure.
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Nasser, Abdallah. "Contribution au développement de méthodes de synthèse pour la conception de filtres hyperfréquences à bandes passantes multiples." Limoges, 2008. https://aurore.unilim.fr/theses/nxfile/default/c7e4f979-10d0-4aef-a281-aeb55b648fda/blobholder:0/2008LIMO4048.pdf.
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Ce travail de thèse concerne le développement de méthodologies de synthèse pour la conception optimale de filtres hyperfréquences, plus particulièrement pour la réalisation de filtres multi bandes à résonateurs couplés. Le premier chapitre présente le rôle et l’intégration des filtres hyperfréquences au sein des systèmes de télécommunications ainsi que les principales technologies employées, en particulier pour les dispositifs multi bandes. Dans le deuxième chapitre un état de l’art de la conception des filtres hyperfréquences à résonateurs couplés est présenté. En particulier, ce chapitre présente différentes approches de la génération des fonctions de filtrages multi bandes au dimensionnement du filtre hyperfréquence. Le troisième chapitre présente l'implémentation de divers filtres multi bandes pour des applications spatiales. Enfin, le quatrième chapitre présente une méthodologie de conception permettant d’obtenir une configuration à pertes d’insertion minimales<br>The PHD thesis concerns the development of synthesis methodologies for optimal design of microwave filters, especially for the design of multi-band coupled resonator filters. The first chapter describes the role and the integration of microwave filters in telecommunication systems and the main technologies used, especially for multi-band devices. In the second chapter a state of the art of designing microwave coupled resonator filters is presented. In particular, this chapter presents different approaches for generating multi-band filtering functions. The third chapter presents the design and implementation of multi-band coupled resonator filters for space applications. Finally, the fourth chapter presents a synthesis methodology for implementing microwave filters with a minimum insertion-loss configuration when several coupling topologies or coupling matrices are available with the selected technology
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Deiting, Daniel. "Matrixunabhängige Elementbestimmung in Polymeren mittels Massenspektrometrie mit Induktiv Gekoppeltem Plasma nach Laserablation." Doctoral thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2017. http://nbn-resolving.de/urn:nbn:de:bsz:105-qucosa-227255.
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Die Analyse von organischen Polymeren mittels Massenspektrometrie mit induktiv gekoppeltem Plasma nach Laserablation unterliegt starken Matrixeffekten. Mögliche Korrekturmodelle sollten basierend auf der tatsächlich ablatierten Elementmasse sowie der Signalintensität des Kohlenstoffisotops C-13 (13C-Korrektur) entworfen werden. Damit die 13C-Korrektur erfolgreich verlaufen kann, ist ein direkter Zusammenhang zwischen ablatiertem Kohlenstoff und gemessenem 13C-ICP-MS Signal erforderlich. Dies wurde überprüft, indem unter Anwendung der konfokalen Mikroskopie das Ablationskratervolumen bestimmt und der ablatierte Kohlenstoff berechnet wurde. Dieser Zusammenhang konnte sowohl für undotierte, wie auch für elementdotierte Polymere und die Verwendung verschiedener Ablationsgase (Helium, Argon und Sauerstoff) ermittelt werden. Eigens hergestellte polymere elementdotierte Standardmaterialien wurden hinsichtlich der Matrixeffekte charakterisiert. Als größter Einflussfaktor stellte sich die unterschiedliche Ablationsrate bei der Ablation verschiedener Polymere heraus. Unter Anwendung der tatsächlich ablatierten Elementmasse sowie unter Anwendung der 13C-Korrektur konnte die Matrixabhängigkeit deutlich verringert werden.
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Pather, Sathasivan Indiran. "An investigation of the production of non-coated sustained release beads by extrusion and Spheronization." University of the Western Cape, 1995. http://hdl.handle.net/11394/8457.
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Doctor Pharmaceuticae - DPharm<br>The popularity and increasing complexity of sustained release dosage forms has resulted in increased costs to the patient. One approach to achieve cheaper, yet effective, sustained release medication is through the simplification of production processes. Matrix tablets have been used to sustain the release of numerous drugs and are cheap to prepare. Since they are single-unit dosage forms, however, they display less predictable transit through the gastrointestinal tract. Hence, they provide less reliable blood levels of the drug in comparison with multi particulate dosage forms. Of the various types of multiparticulates available, pellets are popular for oral administration. A fairly recent innovation, in pelletization technology, is extrusion and spheronization. With this technique it is possible to produce pellets with a high degree of drug loading directly and rapidly. The drug loaded beads are usually coated for a sustained release effect. If one could omit the coating step, it would avoid many problems (thus reducing the number of quality control procedures required) and save chemicals, labour and capital for the purchase of additional equipment. The primary aim of this project was to investigate the preparation of non-coated, spheronized sustained release pellets, while a secondary aim was to prepare beads that can be compressed into sustained release tablets. A tablet can accommodate a larger mass and the compaction forces involved may enhance the sustained release effect. Several techniques were used in an attempt to sustain the release of drugs of different solubilities. In one series of formulations, a novel method was used to incorporate a binder consisting of ethylcellulose in ethanol. Using this technique, the release of Theophylline was sustained for
approximately 8 hours. In other formulations, several materials were added to beads with the aim of forming sustained release matrixes. Only magnesium stearate was able to prolong the release of Acetaminophen and Theophylline for a reasonable time. In an attempt to explain why materials that were successfully used in sustained release matrix tablets were of very limited value in beads, an equation was
developed to calculate the approximate distance between the retardant particles. Calculations using this equation revealed that the retardant particles were too far apart, within each bead, to expect consolidation to occur. The discrete retardant particles do not retard drug release effectively. Eudragit?-containing beads, which sustained the release of the drug to a small extent, were successfully compressed into tablets, both on their own and in combination with non pareil seeds. In each case, the sustained release effect was improved by compaction. In the case of the products manufactured with non pareil seeds, the tablets disintegrated rapidly to release the beads, thus ensuring that the advantages of multiparticulates were maintained. Because it was realised that a large amount of the matrix material could not be incorporated within the beads if a high dose drug was formulated with Avicel? PH 101, the idea of forming the matrix outside the beads was developed. Several materials were tried in an attempt to form a sustained release external matrix. Eudragit? RSPO prolonged the dissolution of Theophylline for more than four hours. Magnesium stearate was able to sustain the release of Acetaminophen and Theophylline
appreciably. In the latter case, the dissolution, in water, of a standard adult dose of the drug was prolonged for more than 12 hours. However, the dissolution in an acidic medium was much faster. The described technique represents an advance in extrusion and spheronization technology. While beads containing Cutina? HR did not show promise as sustained release units, they compacted to form sustained release tablets of good appearance and acceptable strength. These tablets were considered to have been efficiently prepared because the constituent beads were easily manufactured and showed good flowability, and because a glidant and a lubricant were not required. The
production of sustained release Indomethacin beads with a more steady release profile than the innovator's product has also been described in other experiments. The research described in this thesis represents progress towards the widespread commercial production of effective non-coated sustained release beads and may encourage further work towards this goal.
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Schwarzbach, Christoph. "Stability of finite element solutions to Maxwell's equations in frequency domain." Doctoral thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2009. http://nbn-resolving.de/urn:nbn:de:bsz:105-24780.
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Eine Standardformulierung der Randwertaufgabe für die Beschreibung zeitharmonischer elektromagnetischer Phänomene hat die Vektor-Helmholtzgleichung für das elektrische Feld zur Grundlage. Bei niedrigen Frequenzen führt der große Nullraum des Rotationsoperators zu einem instabilen Lösungsverhalten. Wird die Randwertaufgabe zum Beispiel mit Hilfe der Methode der Finiten Elemente in ein lineares Gleichungssystem überführt, äußert sich die Instabilität in einer schlechten Konditionszahl ihrer Koeffizientenmatrix. Eine stabilere Formulierung wird durch die explizite Berücksichtigung der Kontinuitätsgleichung erreicht. Zur numerischen Lösung der Randwertaufgaben wurde eine Finite-Elemente-Software erstellt. Sie berücksichtigt unter anderem unstrukturierte Gitter, räumlich variable, anisotrope Materialparameter sowie die Erweiterung der Maxwell-Gleichungen durch Perfectly Matched Layers. Die Software wurde anhand von Anwendungen in der marinen Geophysik erfolgreich getestet. Insbesondere demonstriert die Einbeziehung von Seebodentopographie in Form einer stetigen Oberflächentriangulierung die geometrische Flexibilität der Software<br>The physics of time-harmonic electromagnetic phenomena can be mathematically described by boundary value problems. A standard approach is based on the vector Helmholtz equation in terms of the electric field. The curl operator involved has a large, non-trivial kernel which leads to an instable solution behaviour at low frequencies. If the boundary value problem is solved approximately using, e. g., the finite element method, the instability expresses itself by a badly conditioned coefficient matrix of the ensuing system of linear equations. A stable formulation is obtained by taking the continuity equation explicitly into account. In order to solve the boundary value problem numerically a finite element software package has been implemented. Its features comprise, amongst others, the treatment of unstructured meshes and piecewise polynomial, anisotropic constitutive parameters as well as the extension of Maxwell’s equations to the Perfectly Matched Layer. Successful application of the software is demonstrated with examples from marine geophysics. In particular, the incorporation of seafloor topography by a continuous surface triangulation illustrates the geometric flexibility of the software
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Weißflog, Julia. "Three-dimensional individual and joint inversion of direct current resistivity and electromagnetic data." Doctoral thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2017. http://nbn-resolving.de/urn:nbn:de:bsz:105-qucosa-220995.
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The objective of our studies is the combination of electromagnetic and direct current (DC) resistivity methods in a joint inversion approach to improve the reconstruction of a given conductivity distribution. We utilize the distinct sensitivity patterns of different methods to enhance the overall resolution power and ensure a more reliable imaging result. In order to simplify the work with more than one electromagnetic method and establish a flexible and state-of-the-art software basis, we developed new DC resistivity and electromagnetic forward modeling and inversion codes based on finite elements of second order on unstructured grids. The forward operators are verified using analytical solutions and convergence studies before we apply a regularized Gauss-Newton scheme and successfully invert synthetic data sets. Finally, we link both codes with each other in a joint inversion. In contrast to most widely used joint inversion strategies, where different data sets are combined in a single least-squares problem resulting in a large system of equations, we introduce a sequential approach that cycles through the different methods iteratively. This way, we avoid several difficulties such as the determination of the full set of regularization parameters or a weighting of the distinct data sets. The sequential approach makes use of a smoothness regularization operator which penalizes the deviation of the model parameters from a given reference model. In our sequential strategy, we use the result of the preceding individual inversion scheme as reference model for the following one. We successfully apply this approach to synthetic data sets and show that the combination of at least two methods yields a significantly improved parameter model compared to the individual inversion results<br>Ziel der vorliegenden Arbeit ist die gemeinsame Inversion (\"joint inversion\") elektromagnetischer und geoelektrischer Daten zur Verbesserung des rekonstruierten Leitfähigkeitsmodells. Dabei nutzen wir die verschiedenartigen Sensitivitäten der Methoden aus, um die Auflösung zu erhöhen und ein zuverlässigeres Ergebnis zu erhalten. Um die Arbeit mit mehr als einer Methode zu vereinfachen und eine flexible Softwarebasis auf dem neuesten Stand der Forschung zu etablieren, wurden zwei Codes zur Modellierung und Inversion geoelektrischer als auch elektromagnetischer Daten neu entwickelt, die mit finiten Elementen zweiter Ordnung auf unstrukturierten Gittern arbeiten. Die Vorwärtsoperatoren werden mithilfe analytischer Lösungen und Konvergenzstudien verifiziert, bevor wir ein regularisiertes Gauß-Newton-Verfahren zur Inversion synthetischer Datensätze anwenden. Im Gegensatz zur meistgenutzten \"joint inversion\"-Strategie, bei der verschiedene Daten in einem einzigen Minimierungsproblem kombiniert werden, was in einem großen Gleichungssystem resultiert, stellen wir schließlich einen sequentiellen Ansatz vor, der zyklisch durch die einzelnen Methoden iteriert. So vermeiden wir u.a. eine komplizierte Wichtung der verschiedenen Daten und die Bestimmung aller Regularisierungsparameter in einem Schritt. Der sequentielle Ansatz wird über die Anwendung einer Glättungsregularisierung umgesetzt, bei der die Abweichung der Modellparameter zu einem gegebenen Referenzmodell bestraft wird. Wir nutzen das Ergebnis der vorangegangenen Einzelinversion als Referenzmodell für die folgende Inversion. Der Ansatz wird erfolgreich auf synthetische Datensätze angewendet und wir zeigen, dass die Kombination von mehreren Methoden eine erhebliche Verbesserung des Inversionsergebnisses im Vergleich zu den Einzelinversionen liefert
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Rocha, Haline de Vasconcellos. "Estudo geológico do potencial de exploração e produção de gás natural não convencional na bacia do Paraná: avaliação da viabilidade no abastecimento da usina termoelétrica de Uruguaiana (RS)." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/106/106131/tde-26042016-143019/.
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A presente dissertação de mestrado consiste na realização de um estudo geológico acerca do potencial para exploração e produção de gás natural não convencional na Bacia do Paraná, regiões sul e sudeste do Brasil e norte do Uruguai. Com essa finalidade, foram analisadas as formações geológicas Irati e Ponta Grossa, situadas na porção sul da bacia e caracterizadas por seu potencial gerador de hidrocarbonetos. O estudo também inclui a avaliação da viabilidade do abastecimento da usina termoelétrica de Uruguaiana a partir desse recurso, considerando os aspectos geológicos, socioeconômicos e ambientais associados. O projeto visa incentivar o estudo à temática de recursos energéticos não convencionais, com destaque para o shale gas, principal fonte de gás natural não convencional explorada no mundo, além de ressaltar os benefícios na crescente implantação do gás natural na matriz energética brasileira, tanto em aspectos estratégicos quanto econômicos. O projeto propõe a elaboração de um modelo descritivo-comparativo baseado nos aspectos geológicos dos principais campos produtores de shale gas nos Estados Unidos, principal produtor mundial, por meio do qual é avaliado o potencial para ocorrência desse recurso nos folhelhos negros correspondentes às Formações Irati e Ponta Grossa, segundo parâmetros geoquímicos, petrofísicos e geológicos presentes em formações comprovadamente produtoras nos EUA: Marcellus, Barnett e Eagle Ford. O modelo descritivo tem finalidade de avaliar o potencial para exploração, produção e distribuição de gás natural não convencional nas regiões sul e sudeste do Brasil, as quais representam o maior mercado consumidor e demanda por energia no país. Com base na análise comparativa realizada, atribui-se às formações brasileiras potencial moderado a elevado para a geração de shale gas. Entretanto, a viabilidade no abastecimento da usina termoelétrica de Uruguaiana depende, além da geologia local, de fatores político-regulatórios ainda pouco consolidados no país para a incentivar a produção de recursos energéticos não convencionais.<br>The presented Masters Thesis consists on a geological study of the potential for exploration and production of unconventional natural gas in the Paraná Sedimentary Basin, southern and southeastern Brazil, and northern Uruguay. Therefore, the geological formations Irati and Ponta Grossa, located in the southern portion of the basin, were analyzed in terms of its hydrocarbon generating potential. The study also includes the viability evaluation of this occurrence as a supply for a thermal power plant in Uruguaiana, considering the geological socio-economic and environmental associated aspects. The project aims to promote studies on the topic of unconventional energy resources, especially shale gas, the main unconventional source of natural gas exploited in the world; in addition to emphasizing the advantages in increasing the implement of natural gas into the Brazilian energy matrix, both in strategic and economic aspects. The project proposes the development of a descriptive and comparative model based on geological aspects of the major shale gas producing fields in the United States, the world\'s leading producer; by which we are able to evaluate the potential for occurrence of this resource in the corresponding black shale formations Irati and Ponta Grossa according to geochemical, petrophysical and geological parameters present in these proven producing formations: Marcellus, Barnett and Eagle Ford. The descriptive model was elaborated in order to evaluate the potential for exploration, production and distribution of unconventional natural gas in the southern and southeastern regions of Brazil, which correspond to the largest consumer market and energy demand in the country. Based on a comparative analysis, the Brazilian geological formations are quantified with a moderate to high potential for generating shale gas. However, the viability of using this resource as supply for thermal electricity generation in Uruguaiana depends, in addition to the local geology, to political and regulatory aspects, which are still poorly consolidated among the country, in order to encourage the production of unconventional energy resources.
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Vogel, Sarah, Simon Arnoldini, Stephanie Möller, Ute Hempel, and Matthias Schnabelrauch. "Sulfated hyaluronan alters fibronectin matrix assembly and promotes osteogenic differentiation of human bone marrow stromal cells." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-221028.
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Extracellular matrix (ECM) composition and structural integrity is one of many factors that influence cellular differentiation. Fibronectin (FN) which is in many tissues the most abundant ECM protein forms a unique fibrillary network. FN homes several binding sites for sulfated glycosaminoglycans (sGAG), such as heparin (Hep), which was previously shown to influence FN conformation and protein binding. Synthetically sulfated hyaluronan derivatives (sHA) can serve as model molecules with a well characterized sulfation pattern to study sGAG-FN interaction. Here is shown that the low-sulfated sHA (sHA1) interacts with FN and influences fibril assembly. The interaction of FN fibrils with sHA1 and Hep, but not with non-sulfated HA was visualized by immunofluorescent co-staining. FRET analysis of FN confirmed the presence of more extended fibrils in human bone marrow stromal cells (hBMSC)-derived ECM in response to sHA1 and Hep. Although both sHA1 and Hep affected FN conformation, exclusively sHA1 increased FN protein level and led to thinner fibrils. Further, only sHA1 had a pro-osteogenic effect and enhanced the activity of tissue non-specific alkaline phosphatase. We hypothesize that the sHA1-triggered change in FN assembly influences the entire ECM network and could be the underlying mechanism for the pro-osteogenic effect of sHA1 on hBMSC.
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Marzullo, Rita de Cassia Monteiro. "Metodologia para o cálculo da pegada hídrica ecotoxicológica de produtos dentro de uma perspectiva de ACV com uso do GIS: estudo piloto para o etanol hidratado." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/106/106131/tde-20062016-151922/.
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O presente trabalho apresenta uma proposta metodológica para se determinar a pegada hídrica ecotoxicológica (PHE) de produtos em uma perspectiva de ACV, dentro de uma abordagem crítica sobre o método. Cenários são construídos na forma de um estudo piloto de aplicação da metodologia para o etanol hidratado produzido por uma determinada Usina no Brasil e utilizado como combustível em carros a álcool ou carros flex. O trabalho também sugere que a PHE ou WEF (water ecotoxicity footprint ), na forma de um indicador, sirva de parâmetro tanto para o setor produtivo quanto para o mercado consumidor dentro do processo de tomada de decisão . O setor produtivo poderá utilizar o citado indicador dentro de um programa de metas de redução do nível de ecotoxicidade aquática de seu produto enquanto que, para o consumidor final, o conhecimento da PHE na forma de selo informativo servirá de alavanca rumo à evolução sustentável de nossa civilização que usará o seu poder de escolha na hora de adquirir determinado produto. Dentro da perspectiva de ACV, foram estudadas e inseridas formas de avaliação de impacto, no ponto médio, a nível local e regional com o uso de ferramentas de georeferenciamento. Na intenção de facilitar o uso da ACV no Brasil, o estudo estabelece parâmetros que tornam viável a obtenção de um indicador passível de comparação. Políticas Públicas poderão ser formadas com a possibilidade de incentivar a identificação e mitigação da ecotoxicidade aquática ao longo da cadeia de suprimentos do setor produtivo..<br>This work presents a methodology to determine water ecotoxicity footprint of products in a perspective of LCA within a critical approach to the method. Scenarios are constructed in the form of a pilot study of application of the methodology for hydrous ethanol produced by a given plant in Brazil and used as fuel in flex cars. The work also suggests that the water ecotoxicity footprint, as an indicator, can be used as a parameter for both: the productive sector as well as for theend consumer within the decision-making process. The productive sector can use the cited indicator in a program targeting for reduction in aquatic ecotoxicity of your product while for the end consumer, knowledge of water ecotoxicity footprint in the form of a informative stamp will leverage towards sustainable development of our civilization that uses the power of choice when purchasing a product. From the perspective of LCA, were studied and included forms of impact assessment, at the midpoint, in local and regional level with the use of geo-referencing tools. With the intention of facilitating the use of LCA in Brazil, this study establishes criteria that make possible the comparison . Public policies can be formed with the possibility of encouraging the identification and mitigation of aquatic ecotoxicity along the supply chain of the productive sector..
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Segato, Valdir Donizete. "As principais dificuldades para adoção das normas contábeis: padrão internacional por microempresas e empresas de pequeno porte." Pontifícia Universidade Católica de São Paulo, 2015. https://tede2.pucsp.br/handle/handle/1617.
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Previous issue date: 2015-12-18<br>This study aims to reflect on the main difficulties encountered in the adoption of International Accounting Standards by Micro and Small Entities (MSEs) in Brazil, whose annual gross income is up to R$ 3,600,000.00, based on Technical Interpretation General, established in Resolution n. 1418/12 (ITG 1000), the Federal Accounting Council (CFC). Methodologically, the research is categorized as the objectives in exploratory and descriptive and on the procedures in literature and documents. For the literature review was conducted bibliographic research and in electronic media, content analysis of documents relating to accounting standards, raising opinions through questionnaires and interviews, and a description of the data, based on the elaboration of a materiality matrix, which pondered priorities established by key stakeholders, who are the users of accounting information in relation to the issues involved. The research is justified because of the economic and social importance of this segment which contributes to boost supply chains of large corporations and represents - the Brazilian Service of Support for research Micro and Small Entities (SEBRAE) - 99% of the total of 6.4 millions of existing businesses in Brazil, accounting for 52% (16.1 million) of formal jobs in the private sector. The results showed that the main difficulties for the adoption of this International Accounting Standards by MSEs are not related to the conceptual part of these standards, but the difficulties of structural and operational, as prices services charged (fees) incompatible with the responsibility and technical risk of the work, the absence of management and internal control system, the standard practice of tax evasion, among others, added to some of fact interest that the entrepreneur owner of MSEs demonstrates in relation to accounting as a management tool<br>Este estudo tem por objetivo refletir sobre as principais dificuldades encontradas na adoção do padrão contábil internacional pelas Microempresas e Empresas de Pequeno Porte (MPEs) no Brasil, cuja receita bruta anual é de até R$ 3.600.000,00, com base na Interpretação Técnica Geral, instituída na Resolução nº. 1.418/12 (ITG1000), do Conselho Federal de Contabilidade (CFC). Metodologicamente, a pesquisa se classifica quanto aos objetivos em exploratória e descritiva e quanto aos procedimentos em bibliográfica e documental. Foram realizados levantamentos bibliográficos e em meio eletrônico, análise de conteúdo dos documentos referentes às normas contábeis, levantamento de opiniões por meio de questionários e entrevistas, bem como a descrição dos dados, com base na elaboração de uma matriz de materialidade, que ponderou as prioridades estabelecidas pelos principais stakeholders, que são os usuários das informações contábeis, em relação aos temas envolvidos. A pesquisa se justifica em razão da importância econômica e social deste segmento que contribui para dinamizar as cadeias produtivas das grandes corporações e representa  pela pesquisa do Serviço Brasileiro de Apoio às Micro e Pequenas Empresas (SEBRAE)  99% do total de 6,4 milhões de empresas existentes no Brasil, respondendo por 52% (16,1 milhões) dos empregos com carteira assinada no setor privado. Os resultados obtidos permitem concluir que as principais dificuldades, para a adoção deste padrão contábil internacional pelas MPEs, não estão relacionadas com a parte conceitual destas normas, e sim às dificuldades de ordem estrutural e operacional, como os preços dos serviços cobrados (honorários) incompatíveis com a responsabilidade e risco técnico do trabalho, a inexistência de sistema de gestão e controle interno, a prática recorrente de sonegação de impostos, entre outros, somado ao fato do pouco interesse que o empresário, proprietário das MPEs demonstra em relação à Contabilidade como instrumento de gestão
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Isikdemir, Ozlem. "Investigation Of 8-year-long Composition Record In The Eastern Mediterranean Precipitation." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607064/index.pdf.
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Measurement of chemical composition of precipitation is important both to understand acidification of terrestrial and aquatic ecosystems and neutralization process in the atmosphere. Such data are scarce in the Mediterranean region. In this study, chemical composition of daily, wet-only, 387 number of rain water samples collected between 1991 and 1999 were investigated to determine levels, temporal variation and long-term trends in concentrations of major ions and trace elements between 1991 and 1999. Samples had already been collected and some of the analysis had been completed. The anions SO42-, NO3- and Cl- were analyzed by HPLC coupled with UV-VIS detector, NH4+ was analyzed by colorimetry and H+ ion was analyzed by pH meter. The major ions and trace metals were analyzed by using Atomic Absorption Spectrometry (AAS) and Graphite Furnace Atomic Absorption Spectrometry (GFAAS). In this study complete data set were generated by analyzing samples that had not been previously analyzed for major ions and trace elements with Inductively Coupled Plasma with Optical Emission Spectrometry (ICP-OES).
Statistical tools were used to determine the distribution of the pollutants. The rain water data tends to be log-normally distributed since data show large variations due to meteorological conditions, physical and chemical transformations and air mass transport patterns. The median pH of the rain water was found to be 5.29, which indicates that the rain water is not strongly acidic. This case is not a result of lacking of acidic compounds but rather indicates extended neutralization process in rain water. Eastern Mediterranean atmosphere is under the influence of three general source types: (1) anthropogenic sources, which are located to the north and northwest of the basin brings low pH values to the region (SO42-, NO3- ions)<br>(2) a strong crustal source, which is dried and suspended local soil and air masses transported from North Africa transport which have high pH values (Ca2+, Al, Fe ions) and (3) a marine source, which is the Mediterranean Sea itself (Na+, Cl- ions). In the region, the main acid forming compounds are H2SO4 and HNO3 whereas<br>CaCO3 and NH3 are responsible for the neutralization process.
To describe the level of pollutant concentrations and the factors that affect their variations in rain water<br>ion compositions, neutralization of acidity, short and long-term variability of ions and elements, their time trend analysis and wet deposition fluxes were investigated briefly. Positive matrix factorization (PMF) was used to determine components of ionic mass in the precipitation. In Antalya Station the rain water has five factors: free acidity factor, crustal factor, marine factor, NO3- factor and SO42- factor. Potential Source Contribution Function (PSCF) and trajectory statistics were used to determine source regions generating these components. NO3- has potential source regions of Western Mediterranean countries and North Africa, whereas SO42- has additional southeasterly trajectory components of Israel and south east of Turkey.
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Menzel, Andreas. "Constraints on the Fourth-Generation Quark Mixing Matrix from Precision Flavour Observables." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät, 2017. http://dx.doi.org/10.18452/17711.
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Das Standardmodell einer zusätzlichen sequentiellen Fermiongeneration (SM4) war 2012 auf Basis eines Fits an elektroschwache Präzisionsobservable und die Higgs-Signalstärken mit einer Signifikanz von 5.3 sigma ausgeschlossen worden. Komplementär dazu wurden in der vorliegenden Arbeit Fits des SM4 an eine Kombination eines typischen Satzes von Flavour-Observablen mit den Ergebnissen des zuvor durchgeführten Elektroschwachen Präzisionsfits durchgeführt. Im SM3-Kontext extrahierte Größen wurden gemäß ihrer Bedeutung im SM4 reinterpretiert und die angepassten theoretischen Ausdrücke angegeben. Die resultierenden Einschränkungen der CKM-Matrix des SM4, ihrer potentiell CP-verletzenden Phasen sowie der Masse des up-type-Quarks der 4. Generation t'' werden angegeben. Zum Vergleich des SM4 mit dem SM3 werden die erreichten chi^2-Werte genutzt. chi^2=15.53 im SM4 und 9.56 im SM3 passen fast vollkommen zu einer gleich guten Beschreibung der Experimente durch beide Modelle, wobei das SM3 aber sechs Freiheitsgrade mehr besitzt. Außerdem wurden die Vorhersagen des SM3 und des SM4 für die Dimyon-Ladungsasymmetrie ASL mit experimentellen Werten verglichen. Die Vorhersage des SM3 ist ca. 2 sigma vom experimentellen Wert entfernt, die des SM4 ca. 3 sigma.\par Die Ergebnisse deuten nicht darauf hin, dass die Signifikanz des 2012 erreichten Ausschlusses des SM4 durch die Hinzunahme von Flavour-Observablen zu den damals verwendeten elektroschwachen Präzisionsobservablen und Higgs-Querschnitten bedeutend verringert würde.\par Es konnte jedoch keine genaue quantitative Aussage über die Auswirkungen der Flavourobservablen auf diese Signifikanz getroffen werden, weil das Programm CKMfitter likelihood-ratio-Berechnung nur durchführen kann, wenn sich eines der untersuchten Modelle durch Fixierung von Parametern aus dem anderen ergibt (nested models), was hier nicht der Fall ist.<br>The Standard Model extended by an additional sequential generation of Dirac fermions (SM4) was excluded with a significance of 5.3 sigma in 2012. This was achieved in a combined fit of the SM4 to Electroweak Precision Observables and signal strengths of the Higgs boson. This thesis complements this excludion by a fit of the SM4 to a typical set of Flavour physics observables and the results of the previously performed Electroweak Precision fit. Quantities extracted in an SM3 framework are reinterpreted in SM4 terms and the adapted theoretical expressions are given. The resultant constraints on the SM4''s CKM matrix, its potentially CP-violating phases and the mass of the new up-type quark t'' are given. To compare the relative performance of the SM4 and the SM3, this work uses the chi^2 values achieved in the fit. The values of 15.53 for the SM4 and 9.56 for the SM4 are almost perfectly consistent with both models describing the experimental data equally well with the SM3 having six degrees of freedom more. The dimuon charge asymmetry ASL was not used as a fit input because the interpretation of its measurement was subject to debate at the time when the fits were produced, but its prediction in the fit was used as an additional test of the SM4. The SM3''s prediction differs from the experimental values by about 2 sigma, and the SM4''s prediction by about 3 sigma. \par In summary, these results do not suggest that any significant reduction of the 5.3 sigma exclusion could be achieved by combining the Electroweak Precision Observables and Higgs inputs with Flavour physics data. However, the exact effect of the Flavour physics input on the significance of the SM4''s exclusion cannot be given at this point because the CKMfitter software is currently not able to perform a statistically stringent likelihood comparison of non-nested models.
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Casadiego, Jose, Mor Nitzan, Sarah Hallerberg, and Marc Timme. "Model-free inference of direct network interactions from nonlinear collective dynamics." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-232175.
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The topology of interactions in network dynamical systems fundamentally underlies their function. Accelerating technological progress creates massively available data about collective nonlinear dynamics in physical, biological, and technological systems. Detecting direct interaction patterns from those dynamics still constitutes a major open problem. In particular, current nonlinear dynamics approaches mostly require to know a priori a model of the (often high dimensional) system dynamics. Here we develop a model-independent framework for inferring direct interactions solely from recording the nonlinear collective dynamics generated. Introducing an explicit dependency matrix in combination with a block-orthogonal regression algorithm, the approach works reliably across many dynamical regimes, including transient dynamics toward steady states, periodic and non-periodic dynamics, and chaos. Together with its capabilities to reveal network (two point) as well as hypernetwork (e.g., three point) interactions, this framework may thus open up nonlinear dynamics options of inferring direct interaction patterns across systems where no model is known.
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Stragier, Anne-Sophie. "Elaboration et caractérisation de structures Silicium-sur-Isolant réalisées par la technologie Smart Cut™ avec une couche fragile enterrée en silicium poreux." Thesis, Lyon, INSA, 2011. http://www.theses.fr/2011ISAL0108.
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Au vu des limitations rencontrées par la miniaturisation des circuits microélectroniques, l’augmentation de performances des systèmes repose largement aujourd’hui sur la fabrication d’empilements de couches minces complexes et innovants pour offrir davantage de compacité et de flexibilité. L’intérêt grandissant pour la réalisation de structures innovantes temporaires, i.e. permettant de réaliser des circuits sur les deux faces d’un même film, nous a mené à évaluer les potentialités d’une technologie combinant le transfert de films minces monocristallins, i.e. la technologie Smart Cut™, et un procédé de de porosification partielle du silicium afin de mettre au point une technologie de double report de film monocristallin. En ce sens, des substrats de silicium monocristallin ont été partiellement porosifiés par anodisation électrochimique. La mise en œuvre de traitements de substrats partiellement poreux a nécessité l’emploi de techniques de caractérisation variées pour dresser une fiche d’identité des couches minces poreuses après anodisation et évaluer l’évolution des propriétés de ces couches en fonction des différents traitements appliqués. Les propriétés chimiques, structurales et mécaniques des couches de Si poreux ont ainsi été étudiées via l’utilisation de différentes techniques de caractérisation (XPS-SIMS, AFM-MEB-XRD, nanoindentation, technique d’insertion de lame, etc.). Ces études ont permis d’appréhender et de décrire les mécanismes physiques mis au jeu au cours des différents traitements et de déterminer les caractéristiques {porosité, épaisseur} optimales des couches poreuses compatibles avec les séquences de la technologie proposée. La technologie Smart Cut™ a ainsi été appliquée à des substrats partiellement porosifiés menant à la fabrication réussie d’une structure temporaire de type Silicium-sur-Isolant avec une couche de silicium poreux enterrée. Ces structures temporaires ont été « démontées » dans un second temps par collage polymère ou collage direct et insertion de lame menant au second report de film mince monocristallin par rupture au sein de la couche porosifiée et donc fragile. Les structures fabriquées ont été caractérisées pour vérifier leur intégrité et leurs stabilités chimique et mécanique. Les propriétés cristallines du film mince de Si monocristallin, reporté en deux temps, ont été vérifiées confirmant ainsi la compatibilité des structures fabriquées avec des applications microélectroniques telles que les applications de type « Back-Side Imager » nécessitant une implémentation de composants sur les deux faces du film. Ainsi une technologie prometteuse et performante a pu être élaborée permettant le double report de films minces monocristallins et à fort potentiel pour des applications variées comme les imageurs visibles ou le photovoltaïque<br>As scaling of microelectronic devices is confronted from now to fundamental limits, improving microelectronic systems performances is largely based nowadays on complex and innovative stack realization to offer more compaction and flexibility to structures. Growing interest in the fabrication of innovative temporary structures, allowing for example double sided layer processing, lead us to investigate the capability to combine one technology of thin single crystalline layer transfer, i.e. the Smart Cut™ technology, and partial porosification of silicon substrate in order to develop an original double layer transfer technology of thin single crystalline silicon film. To this purpose, single crystalline silicon substrates were first partially porosified by electrochemical anodization. Application of suitable treatments of porous silicon layer has required the use of several characterization methods to identify intrinsic porous silicon properties after anodization and to verify their evolution as function of different applied treatments. Chemical, structural and mechanical properties of porous silicon layers were studied by using different characterization techniques (XPS-SIMS, AFM-MEB-XRD, nanoindentation, razor blade insertion, etc.). Such studies allowed comprehending and describing physical mechanisms occurring during each applied technological steps and well determining appropriated {porosity, thickness} parameters of porous silicon layer with the developed technological process flow. The Smart Cut™ technology was successfully applied to partially porosified silicon substrates leading to the fabrication of temporary SOI-like structures with a weak embedded porous Si layer. Such structures were then “dismantled” thanks to a second polymer or direct bonding and razor blade insertion to produce a mechanical rupture through the fragile embedded porous silicon layer and to get the second thin silicon film transfer. Each fabricated structure was characterized step by step to check its integrity and its chemical and mechanical stabilities. Crystalline properties of the double transferred silicon layer were verified demonstrating the compatibility of such structures with microelectronic applications such as “Back-Side Imagers” needing double-sided layer processing. Eventually, a promising and efficient technology has been developed to allow the double transfer of thin single crystalline silicon layer which presents a high potential for various applications such as visible imagers or photovoltaic systems
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Khandan, Negin. "Adsorption av Low Density Lipoprotein (LDL) till modifierade agaros matriser." Thesis, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-15418.
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Individer med homozygot familjär hyperkolesterolemi(FH), har höga halter av Low Density Lipoprotein (LDL) vilket leder till ökad risk för kardiovaskulära sjukdomar. Behandling av dessa individer kan göras med extrakorporal elimination av LDL med hjälp av specifika reningskolonner. Syftet med studien var att utvärdera några agarosmodifierade adsorbenter för denna applikation. Adsorbenterna, modifierad polyakrylat (DALI), agaros (Zetaros), direkt sulfateradZetarose och taurin immobiliserad Zetarose, inkuberades med humant plasma spädd med PBS, och en volyms förhållande mellan matris och plasman på 1:5. Inkubering utfördes i rumstemperatur under 60 min med kontinuerlig blandning i rotator. Efter inkubation centrifugerades proverna och LDL bestämdes i såväl supernatant som pellet. Totalmängd adsorberade proteiner analyserades också i eluat från erhållen pellet. LDL bestämdes indirekt med hjälp av Friedewaldsformel (LDL = totalkolesterol (TC) –highdensitylipoprotein (HDL) - (0,45 x Triglycerider(TG)). TC och TG bestämdes enzymatiskt medan HDL kvantifierades som TC efter utfällning av LDL med dextransulfat. Resultaten visar tydligt att DALI har god adsorptionsförmåga.Dock uppvisar de modifierade Zetaroserna begränsad adsorptionskapacitet för LDL. Vid desorption av adsorbenterna visar SDS en bättre elueringsförmåga än NaCl relaterad till protein, vilket tyder hydrofoba proteiner. Metodiken som används i studien är lämplig för vidare studier av andra adsorbenter som förväntas användas i kliniska applikationer för elimination av LDL hos FH patienter.<br>Individuals that suffer from homozygote Familiar Hyperkolesterolemia (FH), has increased amounts of Low Density Lipoproteins (LDL) which leads to a higher risk of cardiovascular diseases. Treatment of these individuals can be achieved by extracorporeal elimination of LDL using specific columns. The aim of this study was to evaluate different agarose-modified adsorbents ability to adsorb LDL from human plasma. The adsorbents (DALI, Zetarose, sulphonated Zetarose and taurine immobilized onto Zetarose) were incubated for 60 minutes with human plasma diluted with PBS, in a ratio of 1:5 between the matrix and the plasma during rotation with a rotator. After incubation the samples were centrifuged and the LDL content was determined in both the supernatant and the pellet. The amount proteins adsorbed were assayed by eluting the pellets. LDL was determined indirectly using Friedwalds equation; LDL= Total cholesterol (TC) - High density lipoprotein (HDL)-(0,45x Triglycerides (TG). The values of TC and TG in the sample were determined enzymatically, whilst HDL was quantified as TC after LDL-precipitation by dextran sulfate. The results clearly show that DALI has good adsorption capacity, but none of the modified Zetaroses shows any capacity to absorb LDL from human plasma. Desorption of the adsorbents using SDS gave higher amounts of eluated protein compared to NaCl elution, indicating hydrofobic proteins. However, the methods used in this study could be used to evaluate new adsorbents for LDL-elimination applications in patients with chronic hyperlipemia.
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Sikder, Snahungshu. "Analytical model for force prediction when machining metal matrix composites." Thesis, 2010. http://hdl.handle.net/10155/105.
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Metal Matrix Composites (MMC) offer several thermo-mechanical advantages over standard materials and alloys which make them better candidates in different applications. Their light weight, high stiffness, and strength have attracted several industries such as automotive, aerospace, and defence for their wide range of products. However, the wide spread application of Meal Matrix Composites is still a challenge for industry. The hard and abrasive nature of the reinforcement particles is responsible for rapid tool wear and high machining costs. Fracture and debonding of the abrasive reinforcement particles are the considerable damage modes that directly influence the tool performance. It is very important to find highly effective way to machine MMCs. So, it is important to predict forces when machining Metal Matrix Composites because this will help to choose perfect tools for machining and ultimately save both money and time. This research presents an analytical force model for predicting the forces generated during machining of Metal Matrix Composites. In estimating the generated forces, several aspects of cutting mechanics were considered including: shearing force, ploughing force, and particle fracture force. Chip formation force was obtained by classical orthogonal metal cutting mechanics and the Johnson-Cook Equation. The ploughing force was formulated while the fracture force was calculated from the slip line field theory and the Griffith theory of failure. The predicted results were compared with previously measured data. The results showed very good agreement between the theoretically predicted and experimentally measured cutting forces.<br>UOIT
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Nagel, Dominik. "The condition number of Vandermonde matrices and its application to the stability analysis of a subspace method." Doctoral thesis, 2021. https://repositorium.ub.uni-osnabrueck.de/handle/urn:nbn:de:gbv:700-202103194121.
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This thesis consists of two main parts. First of all, the condition number of rectangular Vandermonde matrices with nodes on the complex unit circle is studied. The first time quantitative bounds for the extreme singular values are proven in the multivariate setting and when nodes of the Vandermonde matrix form clusters. In the second part, an optimized presentation of the deterministic stability analysis of the subspace method ESPRIT is given and results from the first part are applied.
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Matić, Rada. "Estimation Problems Related to Random Matrix Ensembles." Doctoral thesis, 2006. http://hdl.handle.net/11858/00-1735-0000-0006-B406-B.
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Dathe, Henning. "Der elastisch aufgehängte starre Körper." Doctoral thesis, 2001. http://hdl.handle.net/11858/00-1735-0000-0006-B41F-6.
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