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Dissertations / Theses on the topic 'Maturation'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Papadiamantis, Anastasios. "Maturation and ageing in biominerals with application to enamel maturation." Thesis, University of Birmingham, 2017. http://etheses.bham.ac.uk//id/eprint/7155/.

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Dental enamel consists mainly of calcium-deficient hydroxyapatite (CDHA). The formation and evolution of enamel is a progressive and complex process the final stage of which is post-eruptive maturation (PEM), when mineralisation is completed following tooth eruption and exposure to oral fluids. Although PEM is directly correlated with decrease in caries susceptibility, a complete model to describe the whole process does not exist. Several reports have recently suggested that the previously observed caries decline, which started with the introduction of F- in drinking water and dental products,

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2

Brunious, Wendell J. "Maturation of Practices." ScholarWorks@UNO, 2014. http://scholarworks.uno.edu/td/1855.

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The disparate concepts of Pop Art and abstract painting heavily influence the scope of my work. Finding a link between these two concepts has been the focal point of my studio practices. The apex of my process is the focus on commercial imagery as abstract form. The merging of these two concepts presents a complex composition of balance, color and information. This thesis explores the various concepts as well as influences that have propelled the evolution of my work. It chronicles the steps I have taken in my quest to articulate my conceptual ideas. By describing the works and defining their

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3

Wang, Ling. "Mouse oocyte maturation: How similar is it to frog oocyte maturation?" Thesis, University of Ottawa (Canada), 2005. http://hdl.handle.net/10393/27075.

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In this study, I have attempted to address the similarities/differences between amphibian and mouse oocytes by focusing on two aspects of mouse oocyte maturation. In the first project, I investigated the ability of several antagonists of serotonin receptors to initiate follicle-enclosed mouse oocytes to undergo maturation. I demonstrated that ritanserin, but not any others, was capable of inducing oocyte maturation in the intact mouse follicles. Significantly, ritanserin is also capable of inducing frog oocyte maturation, as demonstrated by others in our lab. These results therefore suggested

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4

Tiklová, Katarína. "Airway maturation in Drosophila." Doctoral thesis, Stockholms universitet, Wenner-Grens institut, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-62419.

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Tubes are a fundamental unit of organ design. Most of our major organs like the lung, kidney and vasculature are composed primarily of tubes. To identify fundamental biological principles of tubular organ formation we used the respiratory organ of Drosophila melanogaster, the trachea.This work dissects embryonic trachea maturation. Three precise epithelial transitions occur during airway maturation. A secretion burst deposits proteins into the lumen; then luminal material is cleared and finally liquid is removed. We identified the cellular mechanisms behind these transitions. Sar1 and γCOP are

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5

Herbert, Mary. "Maturation of human oocytes." Thesis, University of Newcastle Upon Tyne, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362470.

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6

Davies, S. "Oocyte maturation in mice." Thesis, University of Essex, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377928.

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7

Low, Nigel Murray. "Mimicking antibody affinity maturation." Thesis, University of Cambridge, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364567.

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8

Collins, Angela Joyce. "Maturation-related genes from eucalyptus." Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365297.

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9

Soegiharto, Benny Mulyono. "Skeletal maturation assessment in orthodontics." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1445101/.

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Aims: (1) To assess skeletal maturation in orthodontics using hand-wrist and cervical vertebrae methods and (2) To characterise the morphological differences of the craniofacial and cervical vertebrae morphologies at different growth stages in two different populations.;Subjects and Methods for the main study: The study included 2,167 subjects with hand-wrist and lateral cephalometric radiographs. Of these, there were 648 Indonesian males, 303 Caucasian males (age range 10-17 years), 774 Indonesian females and 442 Caucasian females (age range 8-15 years). Each hand-wrist radiograph was observe

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10

Haigh, R. M. "Urogastrone and fetal lung maturation." Thesis, University of Manchester, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377734.

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11

Dempster, Anne Margaret. "Endothelial influences on monocyte maturation." Thesis, University of Aberdeen, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425102.

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The aims of this project were to determine the phenotype of migrating monocytes and examine the influence transmigration has on their differentiation to macrophages or DC. To determine stages of differentiation and activation of monocytes cultured in the presence of autologous serum without endothelium nine cell surface receptors were used. These cells matured over time with an increase in CD16<sup>+</sup> cells and increased major histocompatibility complex II and macrophage mannose receptor (MMR) expression suggesting alternative activation over time compared to cells cultured in foetal cal

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12

Salavati, Mazdak. "Studies on in vitro maturation of dog oocytes to improve maturation rate and development potentials." Thesis, University of Bedfordshire, 2013. http://hdl.handle.net/10547/312054.

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In vitro maturation of dog oocytes has always been the main obstacle preventing reproductive biologist from producing canine in vitro cultured embryos. The unsuccessful oocyte maturation in canine species originates from their unique physiological and biological specifications. Ovulation of dominant follicles in bitch (6-12 in each oestrous cycle) occurs at prophase I stage of oocyte nucleus and meiotic resumption develops during 3-5 days of oviductal transition. During this PhD thesis, studies were designed in order to speculate characteristics of canine oocyte maturation in vitro in terms of

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13

McPherson, Lindsay Rhona. "Energetics and maturation : tracking physiological changes through the maturation cycle of Atlantic herring (Clupea harengus L.)." Thesis, University of Aberdeen, 2010. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=165271.

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This thesis focuses on the link between condition, defined as the magnitude of fat reserves, and maturation in two sub-populations of Atlantic herring (Clupea harengus L.). Histological, fatty acid (FA), univariate and multivariate analyses were used in a multi-scale approach to elucidate the relationship between body fat and maturity. Furthermore, the accuracy of commonly used proxies of condition and maturity was tested. No evidence was found to support the hypothesis that a threshold of fat must be exceeded for first maturation to occur; however, a size threshold was observed. During matura

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14

Scherrer, Serge. "Étude sur la maturation protéolytique du précurseur de la pénicilline g amidase d'Escherichia coli : compétition entre maturation et agrégation in vivo : repliement et maturation du précurseur in vitro : effet de mutations dans le gène sur la maturation." Nancy 1, 1994. http://www.theses.fr/1994NAN10408.

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La pénicilline g amidase (pga) d'e. Coli atcc 11105 est une enzyme de haut intérêt industriel, utilisée pour la production des antibiotiques de type b-lactame. Les pga bactériennes ont la particularité d'être des hétérodimères, produits par une double protéolyse interne d'un précurseur protéique. L'utilisation au niveau industriel de la surproduction de pga par bactéries recombinées semble limitée par l'existence de ce processus de maturation. J'ai employé différentes approches pour essayer d'apporter des informations sur ce processus. Par une étude in vivo, j'ai montré que la surproduction du

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15

Agervald, Åsa. "Maturation and Regulation of Cyanobacterial Hydrogenases." Doctoral thesis, Uppsala universitet, Mikrobiell Kemi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-110871.

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Accelerated global warming plus an increasing need for energy is an equation not easily solved, thus new forms of sustainable energy production are urgently requested. In this context hydrogen production based on a cyanobacterial system offers an environmentally friendly alternative for energy capture and conversion. Cyanobacteria can produce hydrogen gas from sun light and water through the combination of photosystems and hydrogenases, and are suitable to cultivate in large scale. In the present thesis the maturation process of [NiFe]-hydrogenases is investigated with special focus on transcr

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16

Suri, Rakesh Mark. "Dendritic cell maturation, migration and function." Thesis, University of Oxford, 1998. https://ora.ox.ac.uk/objects/uuid:47d2be37-0508-47d6-8b97-a3cf8e39f9f6.

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Dendritic cells (DC) have a fundamental role in priming naive T-cell responses and a suspected importance in the regulation of central and peripheral tolerance. Before DC can be responsibly used in human clinical trials, the generation of both immature and mature subsets must be standardised and their in vivo migratory and functional characteristics explored. The generation of human blood monocyte-derived DC in either fetal calf serum (PCS) or autologous plasma (HP) were compared. Phenotypic and functional assays demonstrated that DC derived from either system were similarly immature and under

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17

Cotta, Doné Stefania. "Nephrin - intracellular trafficking and podocyte maturation /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-411-2/.

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18

Missenden, Kirstie. "Premature sexual maturation : subjectivity and discourse." Thesis, University of East London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.532412.

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19

Harpin, V. A. "The functional maturation of newborn skin." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603732.

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20

Köchl, Robert. "Autophagosome maturation in primary rat hepatocytes." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1444897/.

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Nutrient deprivation of eukaryotic cells elicits a rapid survival response, including the induction of autophagy. Autophagy, or "self-eating", involves the formation of autophagosomes from an unknown membrane source and the sequestration of cytosolic components, including organelles such as mitochondria, endoplasmic reticulum and small vesicles. Autophagosomes then fuse with protease-containing endosomes and their contents are degraded. This allows the cell to recycle amino acids and to reuse them for the synthesis of new proteins. To study the formation and fusion of autophagosomes, I have de

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21

Arora, Natasha. "Developmental Maturation within the Hematopoietic System." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11341.

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Stem cell biologists creating cells and tissues for therapies, disease modeling, and drug screening have observed that differentiating pluripotent stem cells (PSCs) tend to produce cells at an embryonic stage of development but have difficulty maturing into adult definitive cells. A better understanding of developmental maturation will provide insights into embryogenesis and permit more accurate disease modeling. In the hematopoietic system, primitive and definitive cells are distinguished by functional transplantation assays, well characterized cell surface antigens, and gene expression sig

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22

Meltzer, Ulrike Anne. "Dendritic cell maturation and antigen presentation." Thesis, University College London (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407647.

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23

Dalton, C. M. "Mitochondrial dynamics during mouse oocyte maturation." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1335718/.

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Mitochondria provide the primary source of ATP for the oocyte and pre-implantation embryo and undergo a number of redistributions during oocyte maturation which may be related to developmental competence. The experiments presented in this thesis aim to examine the changes in distribution and function of mitochondria during the transition from the germinal vesicle stage to the mature metaphase II arrested egg. Mitochondrial distribution was monitored throughout oocyte maturation and accumulation of mitochondria around the first meiotic spindle was observed. This was dependent on the activities

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24

Galan, Carolina. "Epigenomics of Post-testicular Sperm Maturation." eScholarship@UMMS, 2021. https://escholarship.umassmed.edu/gsbs_diss/1153.

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Beyond the haploid genome, mammalian sperm carry a payload of epigenetic information with the potential to modulate offspring phenotype. Morphologically mature sperm exit the testes, but cannot swim or interact with the oocyte without extensive remodeling during epididymal transit; this includes modifications to the lipid composition of the sperm membrane, gain of necessary proteins, and a dramatic shift in sperm RNA content. Epididymal maturation has also been linked to changes in the sperm methylome suggesting that the epididymis might play a broader role in shaping the sperm epigenome. Firs

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25

Nist, Richard Neil. "Maturation of tRNA in Haloferax volcanii." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1308066223.

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26

Armbruster, David W. "Transfer RNA maturation in the Archaea /." The Ohio State University, 1998. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487952208108583.

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27

Thimon, Véronique. "Protéases et maturation épididymaire des spermatozoïdes." Tours, 2005. http://www.theses.fr/2005TOUR4016.

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La forme germinale de l'enzyme de conversion de l'angiotensine I (ECAg) présente sur la membrane des spermatozoïdes testiculaires apparaît dans le fluide de la tête de l'épididyme, long tube pelotonné reliant le testicule au canal déférent dans lequel les spermatozoïdes de mammifères acquièrent progressivement leur pouvoir fécondant et leur motilité. Cette libération laisse dans la membrane du spermatozoïde la partie C-terminale trans-membranaire et intracellulaire de l'ECAg. Le site de coupure déterminé par spectrométrie de masse se fait entre l'Arg622 et la Leu623 de la séquence de l'ECAg ov

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28

Harney, Ewan. "The evolution of maturation in Daphnia." Thesis, University of Liverpool, 2013. http://livrepository.liverpool.ac.uk/9173/.

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Maturation is a key life history transition for many organisms, due to the importance of age and size at maturity in determining fitness. Understanding how maturation phenotypes evolve requires an appreciation of the underlying ontogenetic mechanisms, including the maturation threshold, which determines when an individual ‘decides’ to mature. Maturation thresholds are poorly understood, and little is known about how phenotypically plastic or genetically variable they are, or how variable thresholds influence fitness. In this thesis the evolution of maturation thresholds is investigated using t

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29

Kaps, Miroslav. "Growth and maturation of angus cattle /." free to MU campus, to others for purchase, 1997. http://wwwlib.umi.com/cr/mo/fullcit?p9842543.

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30

Rossi, Rubiana. "Contribution à la compréhension de l'effet de maturation des graines sur leur qualité physiologique chez les légumineuses." Thesis, Rennes, Agrocampus Ouest, 2016. http://www.theses.fr/2016NSARI077/document.

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Pendant la maturation des graines, la germination, tolérance à la dessication et longévité sont acquises de manière séquentielle. La maturation s’achève par la dessication qui amène l’embryon à l’état de quiescence. La maturité des graines à la récolte est le premier facteur qui in¿ uence la longévité et l’établissement de la culture lors du semis. On ne comprend pas comment la longévité est installée pendant la maturation et comment un séchage prématuré in¿ uence la longévité et la reprise des activités cellulaires pendant l’imbibition. L’objectif de la thèse était de répondre à ces questions

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31

Rouillé, Yves. "Maturation et evolution des pro-hormones neurohypophysaires. La maturation adaptative de la pro-vasotocine amphibienne : les hydrines." Paris 6, 1991. http://www.theses.fr/1991PA066316.

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Les hormones neurohypophysaires sont des nonapeptides amides, matures a partir de precurseurs de 106 a 147 amino-acides contenant une neurophysine et eventuellement une copeptine. L'existence de deux hormones, l'une ocytocique et l'autre vasopressique, chez presque tous les vertebres revele la presence de deux lignees evolutives des poissons aux mammiferes. Dans une lignee, chaque hormone derive de la precedente par une substitution d'un acide amine en position 2, 3, 4 ou 8. Les deux lignees sont probablement issues de la duplication du gene d'une pro-hormone ancestrale. Des duplications addit

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32

Xu, Xiaoji. "Assessment of in vitro maturation and fertilization techniques for evaluation of oocyte maturation and sperm quality in pigs." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq23092.pdf.

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33

Jonge, Wouter Jacob de. "Implications of arginine deficiency for growth and organ maturation studies on hair, muscle, brain and lymphoid organ maturation /." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2001. http://dare.uva.nl/document/59832.

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34

Anderson, Donald P. "Rapid physical development and maturation, delayed behavioral maturation, and single birth in young adult Callimico: a reproductive strategy." The Ohio State University, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=osu1342630196.

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35

Bidzhekov, Kiril. "Investigations on endothelial maturation and anticoagulant properties." Diss., lmu, 2005. http://nbn-resolving.de/urn:nbn:de:bvb:19-41786.

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36

Currie, Ian Stewart. "Proliferation and maturation in developing human liver." Thesis, University of Edinburgh, 2006. http://hdl.handle.net/1842/27856.

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In order to understand how human liver cells can proliferate and differentiate <i>in vitro</i>, a culture system was developed to support second trimester fetal liver cells. Having characterised the culture system, and demonstrated viable hepatocytes after seven days <i>in vitro</i>, cells were incubated with growth factors and cytokines and subject to two-colour flow cytometry to assess which cell fraction might proliferate <i>in vitro</i>. Experiments were then carried out to determine which circulating endocrine stimuli might initiate morphologic and functional maturation in the developing

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37

Sasseville, A. Marie-Josée. "La lamine A, localisation, maturation et interactions." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0012/NQ38833.pdf.

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38

Zhao, Jing. "Tendon and ligament repair regeneration and maturation /." Connect to this title online, 2008. http://etd.lib.clemson.edu/documents/1211389215/.

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39

Dillon, John Edward Michael. "The Greek hero Perseus : myths of maturation." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303522.

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40

Jovanovic, Ksenija. "Progressive maturation of CD4 single positive thymocytes." Diss., Ludwig-Maximilians-Universität München, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:19-168051.

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41

Davidson, Gary. "FGF2 requirement for podocyte maturation in-vitro." Thesis, University of Aberdeen, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311157.

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FGF2 is expressed in renal podocytes as they differentiate <I>in-vivo</I>, as demonstrated by specific antibody staining within developing glomeruli of chicken metanephros. Mice lacking FGF2 have been generated in the laboratory by targeted deletion and kidneys of <I>Fgf2</I> deficient mice appear to develop normally. Detailed histological analysis of adult kidneys from these mice however has revealed low frequency glomerular abnormalities. Additionally, a few obvious cases of glomerulosclerosis with severe podocyte damage were observed specifically in mutant mice. Taken together these observa

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42

Riquet, Fred. "Croissance du membre inférieur et maturation osseuse." Montpellier 1, 1991. http://www.theses.fr/1991MON11185.

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43

Gil-Loyzaga, Pablo Enrique. "Maturation des éléments sensorinerveux de la cochlée." Montpellier 2, 1990. http://www.theses.fr/1990MON20287.

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Le developpement des cellules sensorielles et des elements nerveux de la cochlee a ete analyse sous deux aspects principaux: differenciation des cellules ciliees et maturation neurochimique des fibres efferentes et efferentes. Les principaux resultats, detailles dans dix publications hors-texte concernent: 1) l'expression des antigenes des groupes sanguins b et h au cours des phases-cles de la differenciation cellulaire et de la synaptogenese, 2) la dependance etroite existant entre la differenciation cellulaire et la presence des elements nerveux, 3) la maturite neurochimique precoce de la pl

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44

Virard, François. "Trafic, maturation et signalisation proapoptotique de TLR3." Thesis, Lyon 1, 2011. http://www.theses.fr/2011LYO10337.

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45

Magne, Fabien. "Maturation de la flore intestinale chez l'enfant." Paris, CNAM, 2005. http://www.theses.fr/2005CNAM0511.

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Le tube digestif héberge une flore bactérienne dense et complexe. La flore intestinale exerce différentes fonctions, comme la fermentation des substrats, la production de vitamines essentielles, la stimulation du système immunitaire et la protection vis-à-vis des bactéries pathogènes (effet de barrière). Cette protection vient probablement de la compétition pour les nutriments et pour les sites d'attachement à la muqueuse, mais aussi de la production des substances inhibitrices. Chez l'enfant, la prématurité et l'alimentation sont des facteurs pouvant modifier la flore intestinale et entraîner

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46

Rainey, Billie-Jean. "Reliability of cervical vertebrae maturation staging method." Thesis, University of Liverpool, 2014. http://livrepository.liverpool.ac.uk/18455/.

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Background: Knowledge of craniofacial growth and development is a prerequisite for the comprehensive and successful management of orthodontic patients. In orthodontic treatment during adolescence, craniofacial growth is often paramount to its success of treatment, especially in patients with skeletal discrepancies. The ultimate goal, in orthodontics, would be the ability to predict accurately the onset, duration and magnitude of the peak pubertal growth spurt, particularly in relation to the mandible. The radiographic assessment of features of skeletal maturation has been extensively researche

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47

Archer, Madeline A., Teal M. Brechtel, Leslie E. Davis, Rinkuben C. Parmar, Mohammad H. Hasan, and Ritesh Tandon. "Inhibition of endocytic pathways impacts cytomegalovirus maturation." NATURE PUBLISHING GROUP, 2017. http://hdl.handle.net/10150/623928.

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Endocytic processes are critical for cellular entry of several viruses; however, the role of endocytosis in cellular trafficking of viruses beyond virus entry is only partially understood. Here, we utilized two laboratory strains (AD169 and Towne) of human cytomegalovirus (HCMV), which are known to use cell membrane fusion rather than endocytosis to enter fibroblasts, in order to study a post-entry role of endocytosis in HCMV life cycle. Upon pharmacological inhibition of dynamin-2 or clathrin terminal domain (TD) ligand association, these strains entered the cells successfully based on the ex

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48

Eaton, Laura. "Skin dendritic cells : activation, maturation and migration." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/skin-dendritic-cells-activation-maturation-and-migration(0831ed5e-c580-406c-a404-4b1eb59b040d).html.

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Langerhans’ cells (LC) are the dendritic cells (DC) of the epidermis and, as sentinels of the immune system, act as a bridge between the innate and adaptive immune responses. When LC, and other DC, recognise an antigen or pathogen they mature and are stimulated to migrate to the lymph nodes, where they orchestrate immune responses. Pathogen derived toll-like receptor (TLR) ligands, and chemical allergens, are recognised as being potentially harmful and stimulate LC to mobilise and mature. Cytokine signals, including tumour necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-18, all induce LC

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Corrigan, Douglas Paul. "Role of Zmpste24 in Prelamin A Maturation." Digital Commons @ East Tennessee State University, 2005. https://dc.etsu.edu/etd/1046.

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The nuclear lamins form a karyoskeleton providing structural rigidity to the nucleus. One member of the lamin family, lamin A, is first synthesized as a 74 kDa precursor, prelamin A. Following the endopeptidase and methylation reactions which occur after farnesylation of the CAAX-box cysteine, there is a second endoproteolysis that occurs 15 amino acids upstream from the C-terminal farnesylated cysteine residue. Studies with knockout mice have implicated the enzyme Zmpste24 as a candidate to carry out one or both of these proteolytic reactions. In this body of work, the CAAX endopeptidase acti

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50

Kilaru, Aruna. "Changes in Avocado Transcriptome During Fruit Maturation." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/4774.

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