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1

Long, MengPing, and TaoBo Hu. "Tripartite genome of all species." F1000Research 5 (February 19, 2016): 195. http://dx.doi.org/10.12688/f1000research.8008.1.

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Neutral theory has dominated the molecular evolution field for more than half a century, but it has been severely challenged by the recently emerged Maximum Genetic Diversity (MGD) theory. However, based on our recent work of tripartite human genome architecture, we found that MGD theory may have overlooked the regulatory but variable genomic regions that increase with species complexity. Here we propose a new molecular evolution theory named Increasing Functional Variation (IFV) hypothesis. According to the IFV hypothesis, the genome of all species is divided into three regions that are ‘functional and invariable’, ‘functional and variable’ and ‘non-functional and variable’. While the ‘non-functional and variable’ region decreases as species become more complex, the other two regions increase.
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2

Talekar, S. C., M. Vani Praveena, and R. G. Satish. "Genetic diversity using principal component analysis and hierarchical cluster analysis in rice." INTERNATIONAL JOURNAL OF PLANT SCIENCES 17, no. 2 (2022): 191–96. http://dx.doi.org/10.15740/has/ijps/17.2/191-196.

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A set of 100 germplasm lines with four checks viz., BPT-5204, PSB-68, Siri1253 and MGD-101 were evaluated in augmented block design during Kharif 2020. The observations were documented for 5 quantitative traits viz., days to 50% flowering, panicle length, number of panicles per square meter, 1000 grain weight and grain yield by principal component analysis and cluster analysis to determine the relationship and genetic divergence among the individuals. The cumulative variance of 55.60% was explained by 1st two principal components (PC1 and PC2) with eigen values greater than 1. Component 1 with variance of 32.10% had contribution from days to 50% flowering, panicle length, panicles per square meter and grain yield while principal component 2 accounting 23.50% total variability has contribution from days to 50% flowering and panicles per square meter. The remaining variability of 17.68%, 16.10% and 10.60% was consolidated in PC3, PC4 and PC5. Results from cluster analysis grouped 100 germplasm lines into four clusters with minimum individuals constituted in cluster 1 and maximum individuals were found in cluster 4. The lines in cluster 1 (2.62) showed maximum divergence followed by cluster 3 (2.23). The maximum inter cluster Euclidean distance was observed between clusters 2 and cluster 3 followed by cluster 1 and cluster 2 giving a scope for selection of parents for hybridization programme from these clusters to realize high genetic variation and novel combinations for yield increment.
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3

Huang, Shi. "The maximum genetic diversity theory of molecular evolution." Communications in Information and Systems 23, no. 4 (2023): 359–92. http://dx.doi.org/10.4310/cis.2023.v23.n4.a1.

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4

Rivera, Diego, Francisco Alcaraz, Diego J. Rivera-Obón, and Concepción Obón. "Phenotypic Diversity in Wild and Cultivated Date Palm (Phoenix, Arecaceae): Quantitative Analysis Using Information Theory." Horticulturae 8, no. 4 (2022): 287. http://dx.doi.org/10.3390/horticulturae8040287.

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The quantitative study of genetic diversity requires tools to describe quantitatively and in parallel the whole phenotypic diversity in order to produce meaningful comparisons. The genus Phoenix offers examples of species with very different levels of diversity or heterogeneity. Within Phoenix, date palm (Phoenix dactylifera L.) is a major food crop of global relevance. The concept of information entropy was introduced by Claude Shannon; although initially intended to evaluate data communication systems, it has been used to measure biodiversity in terms of richness, evenness and dominance. In the present work, we will use it to describe heterogeneity within the different taxonomic units in the genus Phoenix. The description of the Phoenix morphological diversity in the present work is based on 596 accessions or populations belonging to 43 mutually exclusive taxonomic units (species, subspecies, varieties, landrace groups and hybrids). As Phoenix is a dioecious palm genus, female and male individuals are described separately. Each accession or sample is described using 116 characters totaling 449 states. The Shannon information entropy index allows the quantitative representation of the different levels of heterogeneity in the various taxonomic units of the genus Phoenix. Morphology, consistency and coloration of fruit and seed, followed by the inflorescences and female flowers, comprise the taxonomic characters that contribute the most to heterogeneity. Vegetative characters contribute less than the characters of the reproductive organs as a whole. Phoenix dactylifera and related Mediterranean and Macaronesian taxa present the maximum heterogeneity. Immediately afterwards we find P. loureiroi and, behind, the group of P. pusilla. At the lower limit of heterogeneity, we find species restricted in their distribution area: P. rupicola, P. theophrasti, P. roebelenii and P. acaulis. Phoenix dactylifera conforms to a complex of landraces and cultivars that coexist as phenotypically well-defined geographical groups with numerous intermediate forms and the long-distance translocation of otherwise local cultivars. This results in high heterogeneity. For the western and eastern groups of Phoenix dactylifera, it is extremely difficult to find a set of well-defined differential characters. However, some of the variables analyzed here allow us to propose a set of their respective syndromes. The high phenotypic heterogeneity in various Phoenix species is related to the genetic diversity, age and ancestry of different taxa, hybridization events and introgressions prior to domestication, and selective pressures after domestication and, again, interspecific crosses after domestication.
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Jones, C. G., J. A. Plummer, E. L. Barbour, and M. Byrne. "Genetic Diversity of an Australian Santalum album Collection – Implications For Tree Improvement Potential." Silvae Genetica 58, no. 1-6 (2009): 279–86. http://dx.doi.org/10.1515/sg-2009-0036.

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AbstractThe Forest Products Commission of Western Australia manages a sandalwood (Santalum spp.) core germplasm collection at Kununurra in the states far north. This collection serves as a significant seed source for sandalwood plantations in the area and remains an important resource for ongoing research. The collection contains S. album trees sourced from Indian arboreta, along with a few trees from West Timor, Indonesia. Also present are representatives of S. macgregorii from Papua New Guinea and S. austrocaledonicum from Vanuatu and/or New Caledonia. Despite the apparently diverse seed origins, the genetic background of many of the accessions remains vague. In this study, diversity and relatedness was assessed by nuclear and chloroplast RFLPs and a phylogeny was inferred. Nuclear RFLPs revealed very low levels of genetic diversity for a tree species, with an observed and expected heterozygosity (Ho and He) of 0.047. Nineteen genotypes were identified within the 233 S. album individuals sampled, with only one tree known to have originated from Timor being differentiated from Indian material. Other trees thought to have come from Timor grouped with those believed to be from India, indicating they were either incorrectly labelled or sourced from heavily modified populations. Despite the poor sample size, chloroplast RFLP analysis revealed no genetic distinction between the Timorese and Indian S. album, which supports the theory of human mediated seed dispersal from Timor to India. The structure of the phylogeny and associated relatedness has assisted in the establishment of seed orchards, designed to ensure maximum diversity is maintained through limiting the proximity of highly related trees. Finally, in light of these and other findings, a hypothesis concerning the evolution of S. album is proposed.
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Abedin, Muhammad Sohe, Ananna Ghosh, Abdul Jabber Howlader, and Md Monwar Hossain. "Molecular identification and genetic diversity of ten Pierid butterflies based on mitochondrial COI gene." Bangladesh Journal of Zoology 51, no. 3 (2024): 289–99. http://dx.doi.org/10.3329/bjz.v51i3.72027.

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The IUCN Bangladesh has documented a total of 31 species belonging to the Pieridae family in Bangladesh. There is currently limited knowledge regarding the genetic diversity and molecular relationships among these butterflies. The present investigation involved the generation of mitochondrial COI (mtCOI) gene sequences for ten species of butterflies belonging to the Pierid family. After that, BLAST analysis showed 96% to 100% similarity, and then the sequences were submitted to NCBI’s GenBank. MEGA10 and BioEdit were used to identify a 584 bp COI gene fragment with 179 variable sites and 128 parsimony-informative sites. The COI sequences' average base compositions were 38.56% T, 17.12% C, 30.18% A, and 14.12% G. While a significant AT bias (68.74%) existed among the Pierid species. The genetic distance between ten Pierid species was assessed using the Kimura 2-Parameter (K2P) algorithm, and the nucleotide differences ranged from 0.00172% to 0.24261%. Afterwards, the Maximum Likelihood (ML) method was used to construct a phylogenetic tree using ten sequences of Pierid species. These species belongs to two subfamilies, Pierinae and Coliadinae in Bangladesh. On the tree, the Pierinae subfamily of Pieridae formed a paraphyletic arrangement whereas the Coliadinae subfamily was shown to be monophyletic. The data analyses support the following relationships between the two subfamilies as follows: [(Appias + Leptosia) + (Pieris + Appias) + (Delias) + (Eurema + Catopsilia) + (Pareronia)]. This supported the theory that Pierinae and Coliadinae are sister taxa. Nonetheless, Pareronia hippia remains outside the main Pierinae group, requiring further study to resolve this issue. Finally, these studies generated ten mtCOI gene sequences that have the potential to serve as valuable references for the accurate identification of Pierid species. In addition, this result could be used in the future to reveal the subfamily relationships within the Pieridae taxonomic classification. Bangladesh J. Zool. 51(3): 289-299, 2023
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NEAL, A. T. "Male gametocyte fecundity and sex ratio of a malaria parasite, Plasmodium mexicanum." Parasitology 138, no. 10 (2011): 1203–10. http://dx.doi.org/10.1017/s0031182011000941.

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SUMMARYEvolutionary theory predicts that the sex ratio of Plasmodium gametocytes will be determined by the number of gametes produced per male gametocyte (male fecundity), parasite clonal diversity and any factor that reduces male gametes' ability to find and combine with female gametes. Despite the importance of male gametocyte fecundity for sex ratio theory as applied to malaria parasites, few data are available on gamete production by male gametocytes. In this study, exflagellating gametes, a measure of male fecundity, were counted for 866 gametocytes from 26 natural infections of the lizard malaria parasite, Plasmodium mexicanum. The maximum male fecundity observed was 8, but most gametocytes produced 2–3 gametes, a value consistent with the typical sex ratio observed for P. mexicanum. Male gametocytes in infections with higher gametocytaemia had lower fecundity. Male fecundity was not correlated with gametocyte size, but differed among infections, suggesting genetic variation for fecundity. Fecundity and sex ratio were correlated (more female gametocytes with higher fecundity) as predicted by theory. Results agree with evolutionary theory, but also suggest a possible tradeoff between production time and fecundity, which could explain the low fecundity of this species, the variation among infections, and the correlation with gametocytaemia.
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8

Kang, Wanmo, GoWoon Kim, and Yongsu Park. "Habitat suitability and connectivity modeling predict genetic population structure and priority control areas for invasive nutria (Myocastor coypus) in a temperate river basin." PLOS ONE 17, no. 12 (2022): e0279082. http://dx.doi.org/10.1371/journal.pone.0279082.

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The nutria (Myocastor coypus), also known as the coypu, is a semi-aquatic, invasive rodent native to South America that causes damage to natural riverine and wetland habitats in many parts of the world, including South Korea. Understanding habitat use, connectivity, and gene flow of nutria populations is critical for the sound management of local and regional ecosystems. Here, we assessed habitat suitability and connectivity in relation to the genetic structure of nutria populations in the Nakdong River Basin of South Korea. A total of 321 nutria occurrence sites and seven environmental variables were used to perform ensemble habitat suitability modeling using five species distribution models (SDMs), including boosted regression trees, maximum entropy model, random forest, generalized linear model, and multivariate adaptive regression splines. Using graph and circuit theory approaches, we assessed the population gene flow and current flow betweenness centrality (CFBC) of suitable habitats derived from the ensemble SDM. All SDMs performed well with a range of test AUC values from 0.962 to 0.970 (mean = 0.966) with true skill statistic values over 0.8. The minimum temperature of the coldest month, mean temperature of the warmest quarter, precipitation of the driest quarter, and distance from water bodies were important predictors in nutria habitat modeling. Nutria population gene flow was significantly correlated with the least-cost path distance on a cost resistance surface based on ensemble habitat suitability modeling and roads (Mantel’s r = 0.60, p < 0.05). Finally, the CFBC positively correlated with the genetic diversity of nutria populations was used to identify priority control areas. Habitat suitability and connectivity modeling not only revealed environmental conditions and areas that support the survival and spread of nutrias, but also improved our understanding of the animals’ genetic population structure, thereby indicating priority areas to target for eradication.
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Tensen, Laura, Arsalan Emami-Khoyi, Anubhab Khan, Gerrie Camacho, Lourens Swanepoel, and Klaus Fischer. "Mitogenomic Characterization of South African Leopards and the Effect of Past Climatic Events." Journal of Zoological Systematics and Evolutionary Research 2024 (May 4, 2024): 1–14. http://dx.doi.org/10.1155/2024/2174469.

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Revealing phylogeographic structure is important for accurate subspecies delineation and understanding a species’ evolutionary history. In leopards (Panthera pardus), there are currently nine subspecies recognized. On the African continent, only one subspecies occurs (P. p. pardus), although mitochondrial DNA from historical samples suggests the presence of three putative continental clades: (1) West Africa (WA), (2) Central Africa (CA), and (3) Southern Africa (SA). So far, whole genome data did not recover this phylogeographic structure, although leopards in the southern periphery of their distribution range in Africa have not yet been investigated in detail. The Mpumalanga province of South Africa is of particular interest, as here, the CA and the SA clade possibly meet. The aim of this study was to characterize the first mitogenomes of African leopards from Mpumalanga, to help clarifying how South African leopards fit into continental patterns of genetic differentiation. Complete mitogenomes from nine leopards, including a strawberry leopard, were assembled de novo and included in phylogenetic analysis, in combination with 32 publicly available mitogenomes. Bayesian inference and maximum likelihood analyses identified two deeply diverged putative clades within South Africa, which were more genetically distinct than two subspecies in Asia. The clades dated back to 0.76-0.86 million years ago, indicating that they originated during the climatically unstable Mid-Pleistocene, as seen in other large mammals. The Pleistocene refuge theory states that the maintenance of savanna refugia in East and Southern Africa promoted the divergence between populations. As such, leopards may reflect the unique climatic history of southern Africa, which has resulted in eminent and endemic genetic diversity.
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Lei, Xu, Bin Feng, Guiping Wang, Weiyu Liu, and Yalin Yang. "A Novel FastSLAM Framework Based on 2D Lidar for Autonomous Mobile Robot." Electronics 9, no. 4 (2020): 695. http://dx.doi.org/10.3390/electronics9040695.

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The autonomous navigation and environment exploration of mobile robots are carried out on the premise of the ability of environment sensing. Simultaneous localisation and mapping (SLAM) is the key algorithm in perceiving and mapping an environment in real time. FastSLAM has played an increasingly significant role in the SLAM problem. In order to enhance the performance of FastSLAM, a novel framework called IFastSLAM is proposed, based on particle swarm optimisation (PSO). In this framework, an adaptive resampling strategy is proposed that uses the genetic algorithm to increase the diversity of particles, and the principles of fractional differential theory and chaotic optimisation are combined into the algorithm to improve the conventional PSO approach. We observe that the fractional differential approach speeds up the iteration of the algorithm and chaotic optimisation prevents premature convergence. A new idea of a virtual particle is put forward as the global optimisation target for the improved PSO scheme. This approach is more accurate in terms of determining the optimisation target based on the geometric position of the particle, compared to an approach based on the maximum weight value of the particle. The proposed IFastSLAM method is compared with conventional FastSLAM, PSO-FastSLAM, and an adaptive generic FastSLAM algorithm (AGA-FastSLAM). The superiority of IFastSLAM is verified by simulations, experiments with a real-world dataset, and field experiments.
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Das, Badhan, and Lenwood S. Heath. "Variant evolution graph: Can we infer how SARS-CoV-2 variants are evolving?" PLOS One 20, no. 6 (2025): e0323970. https://doi.org/10.1371/journal.pone.0323970.

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The SARS-CoV-2 virus has undergone extensive mutations over time, resulting in considerable genetic diversity among circulating strains. This diversity directly affects important viral characteristics, such as transmissibility and disease severity. During a viral outbreak, the rapid mutation rate produces a large cloud of variants, referred to as a viral quasispecies. However, many variants are lost due to the bottleneck of transmission and survival. Advances in next-generation sequencing have enabled continuous and cost-effective monitoring of viral genomes, but constructing reliable phylogenetic trees from the vast collection of sequences in GISAID (the Global Initiative on Sharing All Influenza Data) presents significant challenges. We introduce a novel graph-based framework inspired by quasispecies theory, the Variant Evolution Graph (VEG), to model viral evolution. Unlike traditional phylogenetic trees, VEG accommodates multiple ancestors for each variant and maps all possible evolutionary pathways. The strongly connected subgraphs in the VEG reveal critical evolutionary patterns, including recombination events, mutation hotspots, and intra-host viral evolution, providing deeper insights into viral adaptation and spread. We also derive the Disease Transmission Network (DTN) from the VEG, which supports the inference of transmission pathways and super-spreaders among hosts. We have applied our method to genomic data sets from five arbitrarily selected countries — Somalia, Bhutan, Hungary, Iran, and Nepal. Our study compares three methods for computing mutational distances to build the VEG, sourmash, pyani, and edit distance, with the phylogenetic approach using Maximum Likelihood (ML). Among these, ML is the most computationally intensive, requiring multiple sequence alignment and probabilistic inference, making it the slowest. In contrast, sourmash is the fastest, followed by the edit distance approach, while pyani takes more time due to its BLAST-based computations. This comparison highlights the computational efficiency of VEG, making it a scalable alternative for analyzing large viral data sets.
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Novikov, Arthur I., Vladimir K. Zolnikov, and Tatyana P. Novikova. "Grading of Scots Pine Seeds by the Seed Coat Color: How to Optimize the Engineering Parameters of the Mobile Optoelectronic Device." Inventions 6, no. 1 (2021): 7. http://dx.doi.org/10.3390/inventions6010007.

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Research Highlights: There is a problem of forest seeds quality assessment and grading afield in minimal costs. The grading quality of each seed coat color class is determined by the degree of its separation with a mobile optoelectronic grader. Background and Objectives: Traditionally, pine seeds are graded in size, but this can lead to a loss of genetic diversity. Seed coat color is individual for each forest seed and is caused to a low error in identifying the genetic features of seedling obtained from it. The principle on which the mobile optoelectronic grader operates is based on the optical signal detection reflected from the single seed. The grader can operate in scientific (spectral band analysis) mode and production (spectral feature grading) mode. When operating in production mode, it is important to determine the optimal engineering parameters of the grader that provide the maximum value of the separation degree of seed-color classes. For this purpose, a run of experiments was conducted on the forest seeds separation using a mobile optoelectronic grader and regression models of the output from factors were obtained. Materials and Methods: Scots pine (Pinus sylvestris L.) seed samples were obtained from cones of the 2019 harvest collected in a natural stand. The study is based on the Design of Experiments theory (DOE) using the Microsoft Excel platform. In each of three replications of each run from the experiment matrix, a mixture of 100 seeds of light, dark and light-dark fraction (n = 300) was used. Results: Interpretation of the obtained regression model of seed separation in the visible wavelength range (650–715 nm) shows that the maximum influence on the output—separation degree—is exerted by the angle of incidence of the detecting optical beam. Next in terms of the influence power on the output are paired interactions: combinations of the wavelength with the angle of incidence and the wavelength with the grader’s seed pipe height. The minimum effect on the output is the wavelength of the detecting optical beam. Conclusions: The use of a mobile optoelectronic grader will eliminate the cost of transporting seeds to and from forest seed centers. To achieve a value of 0.97–1.0 separation degree of Scots pine seeds colored fractions, it is necessary to provide the following optimal engineering parameters of the mobile optoelectronic grader: the wavelength of optical radiation is 700 nm, the angle of incidence of the detecting optical beam is 45° and the grader’s seed pipe height is 0.2 m.
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Uzun, Göktuğ, and Özkan Evcin. "Determination of Dispersal Corridors Used by Large Mammals Between Close Habitats." Diversity 17, no. 3 (2025): 165. https://doi.org/10.3390/d17030165.

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In recent years, due to the expansion of cities, the transformation of agricultural areas, the forestry activities carried out solely for wood production, and the spread of transportation networks, natural habitats have become increasingly fragmented, and suitable habitats for wildlife are rapidly decreasing. As a result, natural areas are being divided, connections are being cut off, species’ living spaces are shrinking, and species and habitats are being isolated. This fragmentation significantly hinders the natural movements of large mammals (Ursus arctos, Sus scrofa, and Canis lupus), leading to reduced genetic diversity and threatening the long-term viability of their populations. This research, conducted in the Ballıdağ and Kurtgirmez regions of the Western Black Sea Region of Türkiye, aimed to determine the movement corridors of the brown bear (Ursus arctos), wild boar (Sus scrofa), and wolf (Canis lupus) in the area and to evaluate the habitat connections for these species. This study relied on data obtained through field studies and the previous literature. Ecological modeling was used with the Maximum Entropy Method (MaxEnt) to understand the relationships between these species and environmental variables, and the barriers posed by the latter. Ecological corridor maps were created to evaluate the effects of habitat fragmentation in the region and species’ potential to maintain critical connection points despite this fragmentation using Circuitscape software based on the Circuit Theory approach. As a result of the analysis, it was determined that the AUC values were between 0.75 and 0.8; the most important variables in the models were road density, vegetation, and elevation; focal points and resistance surface areas were determined for three large mammal species; and important ecological corridors were defined between the Ballıdağ and Kurtgirmez regions. This study revealed that preserving habitat connections and reducing fragmentation is critical for the long-term existence of predator species and ecosystem health.
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Sharma, Rakesh Kumar, Krishan Kumar Sharma, and Tarun Varma. "Designing of 2d-IIR Filter Using a Fused ESMA-Pelican Optimization Algorithm (FEPOA)." Informatics and Automation 22, no. 3 (2023): 667–90. http://dx.doi.org/10.15622/ia.22.3.7.

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Many Digital Signal Processing (DSP) applications and electronic gadgets today require digital filtering. Different optimization algorithms have been used to obtain fast and improved results. Several researchers have used Enhanced Slime Mould Algorithm for designing the 2D IIR filter. However, it is observed that the Enhanced Slime Mould Algorithm did not achieve a better solution structure and had a slower convergence rate. In order to overcome the issue a fused ESMA-pelican Optimization Algorithm (FEPOA) is utilized for designing the 2D IIR filter which incorporates the pelican Optimization Algorithm with the Enhanced slime Mould Algorithm (ESMA). At first, the Chaotic Approach is utilized to initialize the population which provides the high-quality population with excellent population diversity, after that the position of population members is to identify and correct the individual in the boundary search region. After that, by the pelican Tactical Approach is to examine the search space and exploration power of the FEPOA, then the Fitness is calculated randomly, and the best solution will be upgraded and then moved towards the iterations. It repeats the FEPOA phases until the execution completes. Then the best solution gives the optimal solution, which enhances the speed of convergence, convergence accuracy and the performances of FEPOA. The FEPOA is then implemented in the IIR filter to improve the overall filter design. The results provided by FEPOA accomplish the necessary fitness and best solution for 200 iterations, and the amplitude response will achieve the maximum value for =2,4,8 as well as the execution time of 3.0158s, which is much quicker than the other Genetic Algorithms often used for 2D IIR filters.
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Шитиков, Владимир Кириллович, Татьяна Дмитриевна Зинченко та Лариса Владимировна Головатюк. "МОДЕЛИ МАКСИМАЛЬНОЙ ЭНТРОПИИ И ПРОСТРАНСТВЕННОЕ РАСПРЕДЕЛЕНИЕ ВИДОВ ДОННЫХ СООБЩЕСТВ НА ТЕРРИТОРИИ СРЕДНЕГО И НИЖНЕГО ПОВОЛЖЬЯ". Российский журнал прикладной экологии, № 2 (25 червня 2021): 10–16. http://dx.doi.org/10.24852/2411-7374.2021.2.10.16.

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Представлены результаты применения метода максимальной энтропии (MaxEnt) для моделирования пространственного распределения видов макрозообентоса на территории Среднего и Нижнего Поволжья. Использовались данные гидробиологического мониторинга многолетних (1990-2019 гг.) исследований донных сообществ в 108 средних и малых реках. В качестве независимых переменных, отражающих условия среды, построенные модели включали климатические и ландшафтные показатели растрового типа, загружаемые с сервера WorldClim (средние температуры, количество осадков, высота и вертикальная расчлененность рельефа). Приводятся результаты тестирования качества и прогнозирующей силы моделей, а также статистические показатели относительной важности каждого из использованных абиотических факторов. Обсуждаются проблемы использования различных алгоритмов построения моделей пространственного распределения видов применительно к данным гидробиологических наблюдений пресноводных лотических экосистем.
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16

Huang, Shi. "Revisiting Human Evolution: Insights from an Expanded Framework of Evolutionary Processes." May 3, 2025. https://doi.org/10.5281/zenodo.15333528.

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Understanding our evolutionary history is a key scientific goal with significant medical, political, and philosophical implications. This endeavor relies on a robust theoretical framework for interpreting evolutionary processes, historically anchored in Darwin's theory of natural selection and Kimura's neutral theory. Traditionally, humans have been viewed as closely related to chimpanzees, with the Recent Out of Africa hypothesis suggesting modern humans originated in Africa. However, these ideas have faced contradictions and have not been fully verified. In recent years, a more comprehensive framework known as the maximum genetic diversity theory has emerged and undergone rigorous testing. This new theory addresses long-standing mysteries, such as the genetic equidistance phenomenon, which earlier theories misinterpreted. Consequently, it has prompted a reexamination of the human evolutionary narrative. New genomic analyses indicate that humans diverged from the pongid clade approximately 18 million years ago, a conclusion supported by various observations. Additionally, this research revisits the Recent Out of East Asia model of modern human origins, first proposed in 1983. Importantly, independent tests have validated these new hypotheses while challenging the prevailing ones. As our understanding of human origins continues to evolve, it will empower us to shape a better future for humanity.
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17

Huang, Shi. "Whole-genome synteny-based phylogeny of apes supports the pongid clade, excluding humans." June 27, 2024. https://doi.org/10.5281/zenodo.12559656.

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Molecular phylogenetic studies utilize protein and DNA sequences to infer phylogeny. The first set of protein alignment results in the 1960s uncovered a most astonishing phenomenon, the genetic equidistance, which directly inspired the molecular clock hypothesis and in turn the neutral theory of molecular evolution. One of the earlier results of molecular phylogeny based on the molecular clock perspective is on the hominids, which surprisingly grouped chimpanzees with humans rather than other great apes, in contrast to the anatomy-based phylogeny popular before the molecular era that groups the great apes into the pongid clade with human as the outgroup. However, recent developments have deemed the molecular clock and the neutral theory flawed in their core claims. The genetic equidistance phenomenon has been reinterpreted by a new evolutionary perspective, the maximum genetic diversity theory. It is now realized that genetic distances are mostly at maximum saturation rather than still scaling with time as misread by the molecular clock. One must choose the few slowly evolving genes that have yet to reach maximum genetic distance to perform phylogenetic inferences. We have previously used the so-called slow clock method to rewrite the hominid phylogeny, which has confirmed the anatomy-based model. Synteny, the conserved collinearity of orthologous genetic loci in two or more organisms, exhibits compelling phylogenomic potential. Using synteny revealed by whole-genome assembly-assembly alignments, we here tested the two competing models of hominid phylogeny and found strong support for the pongid clade through synteny analysis. We provide a first-principle rationale for the pongid clade and review the extensive body of studies that support the pongid clade.
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18

Formoso‐Freire, Victoria, Andrés Baselga, and Carola Gómez‐Rodríguez. "Climatic stability predicts the congruence between species abundance and genetic diversity." Ecography, April 18, 2024. http://dx.doi.org/10.1111/ecog.07200.

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Unified models of biological diversity across organizational levels (genes, species, communities) provide key insight into fundamental ecological processes. Theory predicts that the strength of the correlation between species abundance and genetic diversity should be related to community age in closed communities (i.e. abundant species accumulate more genetic diversity over time than rare species). Following this rationale, we hypothesize that historical climatic events are expected to impact assembly processes, hence affecting both the species abundance distribution (SAD) and the species genetic distribution (SGD) in continental communities. Therefore, we predict that, if the congruence between SADs and SGDs depends on community age, then higher congruence would be observed in localities where climate has been more stable since the Last Glacial Maximum (LGM). We tested this prediction using relative abundance and nucleotide diversity (cox1‐5′) data from 20 communities of leaf beetles along a latitudinal transect in the Iberian Peninsula. We observed that the congruence between SAD and SGD curves, measured as the correlation between the species' rank orders in both distributions, was significantly related to the change in mean annual temperature since the LGM, but not to current climatic conditions. Our results suggest that, despite the high connectivity of continental communities, historical climatic stability is still a relevant predictor of the congruence between species abundance and genetic diversity. Hence, the degree of congruence between SADs and SGDs could be used as a proxy of community stability, related not only to historical climatic variation but also to any other disrupting factors, including human pressure.
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19

Zahra, Syeda Anber, Javed Iqbal, Banzeer Ahsan Abbasi, et al. "Phylogenetic analysis of selected species of Asteraceae on the basis of RPS 11 Gene." Scientific Reports 14, no. 1 (2024). http://dx.doi.org/10.1038/s41598-024-75991-0.

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AbstractThe Asteraceae family is a prominent group of flowering plants found across the globe, with the exception of Antarctica. The Asteraceae family is a largest flowering family pivotal group in plant evolution and diversification. Despite its importance, the genetic diversity within this family remains understudied. We focused on the rps-11 gene, a chloroplast marker previously utilized in phylogenetic studies, to investigate its potential in resolving Asteraceae relationships. The focus was on examining genetic diversity within sixteen specifically chosen species from the Asteraceae family. This assessment was based on an analysis of a chloroplast gene responsible for encoding the ribosomal protein of the smaller subunit 11 (rps 11). Nearly 417 bp of rps 11 gene was amplified, sequenced, computationally translated into amino acid sequence and the data was used for phylogenetic analysis as well as for rps 11 protein structure predictions. Based on nucleotide and amino acid sequences phylograms were drawn with the help of Molecular Evolutionary Genetic Analysis (MEGA 6), which exhibited clear genetic relationship among species under investigation. The observed genetic distance was 0.02 for Maximum likelihood tree based on nucleotide sequences whereas it was 0.05 for phylogram based on amino acid sequences. These values revealed that amino acid-based tree has demonstrated greater diversity among selected species in comparison to nucleotides-based tree. On the basis of pair wise distance calculations, genetic divergence values were found within the range of 0.015–0.309. Moreover, 3D protein modeling for rps 11 protein of sixteen selected species was also carried out by iterative threading assembly refinement (I-Tasser) software. The models exhibiting the highest C-score were picked with satisfactory plot statistics (> 90%) and structurally validated by PROCHECK. Furthermore, Ramachandran plots displayed that the rps 11 protein structures of Tagetes minuta, Xanthium strumarium, Lactuca sativa and Chrysanthemum indicum have best feature models with > 90% of residues in the allowed region and ≤ 2% in the disallowed region. The research is not enough to stand alone to validate the viability of the rps11 gene as a prospective contender for phylogenetic analysis. İn future we will focus on the maximum genetic diversity theory for phylogenetic analysis of this family.
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20

Aylward, Cody M., and Charlotte L. Roy. "Landscape genetics of spruce grouse at the trailing edge of the boreal forest." Wildlife Biology, August 7, 2024. http://dx.doi.org/10.1002/wlb3.01221.

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Populations on the periphery of a species range generally occupy marginal or less continuous habitat and can have greater extinction risk than populations in the range‐center. For climate‐sensitive populations on the trailing edge of a species' distribution (i.e. low latitude or low elevation), the effects of climate change are expected to compound these threats, increasing the vulnerability of these populations. The spruce grouse Canachites canadensis is a boreal forest specialist that is expected to experience range contraction at the trailing edge of its range due to climate change. In this study, we investigated the genetic structure, genetic diversity, and connectivity of spruce grouse in Minnesota, along the southeastern range limit in the United States. Clustering algorithms and genetic diversity indices suggested a single continuous population occurred throughout northern Minnesota. We detected no signatures of recent inbreeding or population bottlenecks. We used maximum likelihood population effects modeling and identified coniferous forest land cover and lower average spring temperatures as predictors of gene flow. We used two approaches based on circuit theory to map the potential for gene flow and identified regions of consistently high gene flow in the northwest and northeast of the study area. Omniscape, which incorporated additional parameters representing the likely origins of dispersers and the maximum dispersal distance, suggested a more continuous gene flow landscape than did Circuitscape. Our work highlights the current genetic integrity of one of the largest populations of the eastern subspecies of spruce grouse C. c. canadensis in the United States, identifies key landscape attributes for functional connectivity, and demonstrates complementary approaches of Circuitscape and Omniscape for gene flow mapping.
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21

Baden, Andrea L., Amanda N. Mancini, Sarah Federman, et al. "Anthropogenic pressures drive population genetic structuring across a Critically Endangered lemur species range." Scientific Reports 9, no. 1 (2019). http://dx.doi.org/10.1038/s41598-019-52689-2.

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Abstract In recent decades Madagascar has experienced significant habitat loss and modification, with minimal understanding of how human land use practices have impacted the evolution of its flora and fauna. In light of ongoing and intensifying anthropogenic pressures, we seek new insight into mechanisms driving genetic variability on this island, using a Critically Endangered lemur species, the black-and-white ruffed lemur (Varecia variegata), as a test case. Here, we examine the relative influence of natural and anthropogenic landscape features that we predict will impose barriers to dispersal and promote genetic structuring across the species range. Using circuit theory, we model functional connectivity among 18 sampling localities using population-based genetic distance (FST). We optimized resistance surfaces using genetic algorithms and assessed their performance using maximum-likelihood population-effects mixed models. The best supported resistance model was a composite surface that included two anthropogenic features, habitat cover and distance to villages, suggesting that rapid land cover modification by humans has driven change in the genetic structure of wild lemurs. Primary conservation priority should be placed on mitigating further forest loss and connecting regions identified as having low dispersal potential to prevent further loss of genetic diversity and promote the survival of other moist forest specialists.
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22

"Genetic Analysis of Submergence Tolerance Rice Genotypes by Introgression of Sub1 QTL to Indica HYV through Breeding Populations (F2) with Marker Assay." American Journal of Pure and Applied Biosciences, February 19, 2022, 10–21. http://dx.doi.org/10.34104/ajpab.022.010021.

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More than 2.0 million-hectare area was affected by flash floods of various grades and reduced the average yield in Bangladesh by 5%. It involves introgression of Sub1 QTL into the genetic background of HYV rice through marker-assisted breeding and to evaluate submergence tolerance of high yielding rice varieties. SSR profiling was performed to tag the submergence tolerant QTL by using sub1 flanking markers and F1 confirmation of Binadhan-7 x BRRI dhan52 (F1) by using the primer RM1115. The gene diversity value was 0.7610 and the polymorphism information content (PIC) values were 0.7432 & allele frequencies (%) were 0.3328. Binadhan-7 x BRRI dhan52 (F2) crosses were possessed the highest grain yield plant-1 (38.00 g) which was significantly higher than its both parents and also early maturing as 124 days from all crosses. The genetic similarity analysis using UPGMA (Unweighted Pair-Group Method using the Arithmetic Average) clustering system generated 5 major genetic clusters. Maximum intra-cluster degree of diversity was observed in cluster4 (79.93) and minimum in cluster3 (31.44). Highly significant and positive correlations were found among the grain yield (GY) and Total tillers/plant, effective tillers/plant, panicle length, and filled grains/panicle. The first three principal components with Eigen-values explained 73.7 % of the total variation among 16 rice genotypes for the 9 quantitative traits studied. However, it is hoped that promising Sub1 cross combination Binadhan-7x BRRI dhan52 will be able to develop three to four weeks tolerance with high yielding submergence tolerant varieties to increase rice production in submerged prone areas of Bangladesh where single flash floods occur under different cropping patterns.
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23

Ma, Zeqing, Thomas N. Buckley, and Lawren Sack. "The determination of leaf size on the basis of developmental traits." New Phytologist, February 24, 2025. https://doi.org/10.1111/nph.20461.

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Summary Mature leaf area (LA) is a showcase of diversity – varying enormously within and across species, and associated with the productivity and distribution of plants and ecosystems. Yet, it remains unclear how developmental processes determine variation in LA. We introduce a mathematical framework pinpointing the origin of variation in LA by quantifying six epidermal ‘developmental traits’: initial mean cell size and number (approximating values within the leaf primordium), and the maximum relative rates and durations of cell proliferation and expansion until leaf maturity. We analyzed a novel database of developmental trajectories of LA and epidermal anatomy, representing 12 eudicotyledonous species and 52 Arabidopsis experiments. Within and across species, mean primordium cell number and maximum relative cell proliferation rate were the strongest developmental determinants of LA. Trade‐offs between developmental traits, consistent with evolutionary and metabolic scaling theory, strongly constrain LA variation. These include trade‐offs between primordium cell number vs cell proliferation, primordium mean cell size vs cell expansion, and the durations vs maximum relative rates of cell proliferation and expansion. Mutant and wild‐type comparisons showed these trade‐offs have a genetic basis in Arabidopsis. Analyses of developmental traits underlying LA and its diversification highlight mechanisms for leaf evolution, and opportunities for breeding trait shifts.
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24

He, Xin, Zhijie Song, Yanqun Yang, et al. "Compatibility optimization of the traditional Chinese medicines ‘Eczema mixture’ based on back-propagation artificial neural network and non-dominated sorting genetic algorithm." Frontiers in Pharmacology 16 (May 2, 2025). https://doi.org/10.3389/fphar.2025.1593783.

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IntroductionChinese medicine formulas (CMF) are an important aspect of traditional Chinese medicine (TCM) and are formulated based on strict compatibility proportions guided by TCM theory. Due to the complex chemical constituents of TCM and the diversity of evaluation indicators for a certain disease, the research strategy on how to obtain the optimal combination of these crude extracts, homologous compounds or even the specific compounds mixture becomes the key step in the study of compatibility proportion research. Therefore, in this research, the “Eczema mixture” (EM) which includes six kinds of Chinese medicinal materials for the treatment of atopic dermatitis was cited as an example to illustrate the proposed compatibility optimization strategy.MethodsUltra-performance liquid chromatography-quadrupole/time-of-flight (UPLC-Q/TOF) technology was used to analyze the chemical components in the EM formula, and a total of 136 chemical compounds were identified. 76 formulas with different compatibility ratios were generated with the simplex centroid mixture design (SCMD). Two defined objective functions, the maximum of the anti-inflammatory and anti-allergic activity were used to evaluate the bioactivities of all the formulas. The 6-n-2 three-layers of back-propagation artificial neural network (BP-ANN) was employed to model the two defined objective functions. With the predictive models, the Pareto front was determined by a variant of non-dominated sorting genetic algorithm II(VNSGAII) to provide the optimal prescription set.ResultsThe 6-n-2 three-layers of artificial neural networks demonstrated a satisfactory fitting effect for the nonlinear activity relationship. In the EM formula, Huangbai and Kushen were identified as the main botanical drugs with anti-inflammatory and anti-allergic roles. The results were consistent with the clinical application of the 113 prescriptions involving 230 botanical drugs for the treatment of AD from the ‘Dictionary of Traditional Chinese Medicine Prescription’.ConclusionThe proposed SCMD-ANN-VNSGAII is a powerful approach that may facilitate future compatibility optimization of homologous compounds or specific component mixtures.
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25

Bhupati, Neupane, Zhao Junmeng, and Dhakal Sanjev. "Tectonics Influence The Climate Change In The Himalayan Orogenic Belt." North American Academic Research 2, no. 1 (2019). https://doi.org/10.5281/zenodo.3250423.

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<strong>Introduction</strong> The high altitude mountain system (i.e., Himalaya) and the Tibetan Plateau region formed after the intracontinental collision of the Indian and Eurasian plates during 55&ndash;50 Ma (Neupane et al., 2017 and reference therein). The Himalayan range, separating the plains of the Indian subcontinent from the Tibetan Plateau, extends 2,400 km-long from east - Namcha Barwa and west Nanga Parbat south of the northernmost bend of Indus river. The entire Himalayan region divided into four tectonostratigraphic zones from south to north;the Tethys Himalaya, Higher Himalaya, Lesser Himalaya, and Sub Himalayan which are bounded and separated by several south propagating,north-dipping thrust/fault systems in different time spans (Neupane et al., 2018 and reference therein). The significant climate change occurred in Tibetan Plateau after rapidly uplifted at 7-8 Ma (Kappa et al., 2008; Murphy et al., 1997). The mechanics of the fold-and-thrust belts that flank many collisional mountain ranges, where the role of erosion in the tectonic evolution of mountain ranges was well known in the mid-1980s (Whipple, 2009). Dahlen et al. (1984), Davis et al. (1983) Stockmal (1983) described tapering wedges theory, a combination of sandbox experiments, analytical treatments of stress state and field observations which explained that fold-and-thrust belts form tapering wedges. After the advancement of critical-taper theory, researchers applied the rate and pattern of erosion of critical-taper orogenic wedges effectively dictates many aspects of the tectonic and structural evolution of mountain belts.Erosional efficiency determines the rate of erosion for a particulartopography and depends on rock type, debris size, and climate(Whipple, 2009). The deformational and exhumation response to induced by enhanced precipitation on windward slopes and rainshadow development on leeward slopes, which is well matched by near-surface rock-uplift patterns and the metamorphic grade of exposed rocks in several active mountain ranges. Recently, Mountainous Region suffers several climatic impacts on several sectors like water availability, biodiversity, high-elevation ecosystem changes, monsoonal shifts, and loss of soil carbon (Xu et al., 2008). Mountainous region is sensitive indicators of climate change (Nijssen et al., 2001). These are also vulnerable to soil erosion, landslides, GLOF, and the rapid loss of habitat and genetic diversity. In several developing countries, in part because of the degradation of the natural environment, there is widespread unemployment, poverty, poor health and bad sanitation (Price et al., 2000). &nbsp; <strong>Fig.1:</strong> a) Location map of the Greater Himalayan region showing all areas with alpine (red), montane (yellow) zones, major river system and has impacts on lowland areas (light green) (adapted from (Qiu, 2008; Xu, 2008). b) General geological map of Himalaya (modified after Neupane et al., 2018) There are several researchers studies in the Himalayas and found that glaciers in the region have retreated significantly in the last two decades (Owen et al., 2002; Parmesan, 2006; Price et al., 2000; Qiu, 2008). Recently, some researchers identified the formation and growth of a number of glacial lakes, possibility to retreat of glaciers, which could lead to the catastrophic outburst,floods (Owen et al., 2005). Some of the researchers believed that the main cause of Glacier retreat is global warming. Fluctuations in air temperature and precipitation also affect the glacier fluctuation over the last decade (Owen et al., 1998). The climatic impact caused the Himalayan glaciers have been retreating since 1850 A.D. It is possible that the cooling in 1940 observed in the global record caused reformed of these glaciers, and the warming after the mid-1970s resulted in accelerated shrinking in the past two decades (Owen et al., 2000). The Himalaya and Tibetan Plateau play a significant role in regional climate, which affect the monsoon circulation. Associations of the monsoon and other global-scale phenomena extend the implications of climatic variations in the Himalaya and in the Tibetan Plateau beyond the regional scale (Bolch et al., 2012; Immerzeel et al., 2010). The analysis of climatic variables showed a considerable increase in minimum and maximum temperature during the last century (i.e. 1901&ndash;2017) coupled with a continuous increase in solid precipitation (Taloor et al., 2018). The Greater Himalayan region is also known as the Water Tower of Asia, covers approximately 7 million km<sup>2</sup>(Xu et al., 2008) (Fig. 1). They are the source of 10 of the largest rivers in Asia (Fig. 1). Therefore, these basins provide water for about 1.3 billion people who stay near this area (Paul A and Jeschke, 1979). All over the world the mountains area like Andes Himalayas, from Southeast Asia to East and Central Africa, there is serious ecological deterioration. Mainly the mountain areas are experiencing environmental degradation. About 40% of the global population lives in the watersheds of rivers originating in the planet&#39;s different mountain ranges (Benn and Owen, 1998). Mountains also symbolize the unique areas for the detection of climatic change and the assessment of climate-related impacts. The great climatic impact on the climate of the Himalayan regions caused the effects on glacier mountains, cascading effects on river flows, groundwater recharge, natural hazards, and biodiversity; ecosystem composition, structure, and function; and human livelihoods (Nijssen et al., 2001; Parmesan, 2006). &nbsp; <strong>2. Overview of recent climate change study in the greater Himalaya region</strong> There are several researchers involved to explain the problem and they applied different methods to acquire some concept about climate change and its impact on Greater Himalayan region.Owen et al. (2002) reconstructed the different numerical data and Barnard and Owen et al. ( 2000) reviewed the glacial geology of other Himalayan regions and for a selective bibliography for Late Quaternary glaciations in Tibet and the bordering mountains. They also used the optically stimulated luminescence (OSL) and cosmogenic radionuclide (CRN) surface exposure dating of moraines and their associated landforms.For the similar purposed Paul and Jeschke, (1979)studied on the topic of the Himalaya and trans- Himalaya glacier fluctuation since AD 1812. They update previous summaries and introduce an additional 27 glaciers for a total of 112 records of glacier fluctuations in the Himalayan and Trans &ndash; Himalayan area. Data used in this synthesis are presented in the form of frequency diagrams of glacier activity in which glacier activity is plotted for 10-yr periods. &nbsp; <strong>Fig. 2</strong>: The current elevational distribution of life zones in the central Himalayas (top) showing the future climate distribution (bottom) with a 5 ◦C temperature rise (Xu et al., 2008). Similarly, Xu et al. (2008)described the issue of Melting Himalayas; cascading Effects of Climate Change on Water, Biodiversity, and Livelihoods. They compiled data on temperature and Precipitation, Glacial Response, Runoff and River Responses, Water-Related Hazards, Phenology, Pollination, and Predator-Prey Interactions, Endemism, and Extinction, Shifting Tree Lines, Ecosystem Composition and Dynamics, Cascading Effects, Effects on Ecosystems and Livelihoods, Downstream and Global Effects (Fig. 2). Bolch et al. (2012) worked on the Himalayan Glaciers trend to used mainly historic data; vary between 43,178 km<sup>2</sup> and 49,650 km<sup>2</sup>. The researcher used the recent satellite images and remote sensing for mapping purposed. They described some model for the glacier, which discusses projections of possible future changes, summarize important implications for water resources and natural hazards, and close by sketching a framework for integrated cryosphere research needed to fill the most critical gaps.Impact of warmer climate on melt and evaporation for the rainfed, snowfield and glacier-fed basins in the Himalayan region, Singh and Bengtsson (2005) used the different method for this research. Researchers mention the different parameters during the research, projected climatic changes over Indian sub-continent and India, hydrological models and structure of snowmelt model. Zhisheng et al. (2001) proposed climate-model simulations, which show that continued uplift andexpansion of the plateau along its northern and eastern margins increases both summer and winter monsoons in the region of the Loess plateau/East Asia and continues the drying trend in central Asia. Where a little change in the general Asian summer monsoon circulation or the Indian monsoon precipitation. In the central Himalaya (Nepal), Blythe et al. (2007) and Huntington et al. (2006), have documented an acceleration of long-term rock cooling rates starting between 0.9 and 2.5 Myr, roughly coincident with the onset of Quaternary glaciations. Due to the absence of evidence for far-field tectonic change and for a change in structural geometry over this time interval, Huntington et al. (2006)suggested that this change in cooling rate represents a climatically triggered acceleration of exhumation rate. Taloor et al. (2018) studied in the Tectono-climatic response to landscape changes in the glaciated Durung Drung basin, Zanskar Himalaya, India, and they analyzed through quantitative morphometric analysis emphasizing on topography and landscape changes in glaciated that basin. &nbsp; <strong>3. Discussion and interpretation </strong> From the above results of Owen at al. (2002), obtained results indicate that the similar pattern of glaciation occurred in each study area and local LGM occurred early in the last glacial cycle. Similar hypothesis purposed by (Gillespie and Molnar, 1995) and (Benn and Owen, 1998), the maximum extent of glaciation in the Himalaya occurred before then the LGM spaced along the length of the Himalaya. It suggests that restricted glacier advance during the LGM is characteristic of the entire Himalaya. The nature of glaciations of the Himalaya controls the dominant climatic system of South Asian summer monsoon (Benn and Owen, 1998). (Benn and Lehmkuhl, 2000), have warned of the difficulties of determining ELAs on the steep debris-covered glaciers in the high-altitude Himalaya where the relationship between glacier mass-balance characteristics and climatic variables such as precipitation and air temperature is very complex in these situations. The fluctuation records of glaciers in the Himalayas differ from those of glaciers in the Trans-Himalayas (Paul A and Jeschke, 1979). Most of the glaciers in the Himalayas have been in a general state of retreat since AD 1850. In the same task, sampling a much smaller number of glaciers than the number sampled, (Tewari, 1971), found the similar result of that the Himalayan glaciers were in a general state of retreat while the Trans-Himalayan glaciers have a more complicated record. The obtained results in (Fig. 2), the current elevation distribution of life zones in the Himalayas and their distribution with a 5<sup>0</sup>C temperature rise (Xu et al., 2009), indicated that elevational distribution of life zones would shift significantly. An additional effect on alpine vegetation shrank, evergreen forest decreased significantly, and tropical lowland forest increased. The effect of warm climate is the region of temperature increases, shifts in ecosystems, and increased frequency and duration of extreme events. This research deals three types of adaptation occurred in Himalayan regions; local community, urban and rural, and regional and transboundary.&nbsp; (Bolch et al., 2012) observed the change of length more than 100 glaciers in Himalaya and Karakoram(H-K), suggest that most Himalayan glaciers have been retreating since the mid-19th century, except for 1920 to 1940. In the eastern Hindu Kush, west of the Karakoram, 25% of the glaciers were stable or advancing from 1976 to 2007.&nbsp; North of the Karakoram, in the Wakhan Pamir, glaciers were retreating during a similar period. Thousands of glaciers in H-K were changed the original position due to the warm climate. Therefore, the area change data shows that the Yarkant basin north of the main ridge, loss rate was ~0.1% year&minus;1 between 1962 and 1999. Similarly, high-altitude glaciers in the Transhimalaya of Ladakh had a shrinkage rate of ~0.4% year&minus;1 from 1969 to 2010 and the Indian Himalaya, shrinkage rates are regionally variable: ~0.2 to ~0.7% year&minus;1, the 1960s to 2001&ndash; 2004. Likewise, (von Cvitković et al., 1935)and (Mayewski and Jeschke, 1979) deals the same trend of results. The above result indicates that the warm and diverse climate directly affect the Glacier. (Singh and Bengtsson, 2005) explained the current effect in Himalayan regions which shows a comparison of the annual evaporation occurred in different types of basins under current temperature (T + 2<sup>0</sup>C) condition and warmer climate (T + 2 <sup>0</sup>C) scenario. &nbsp; <strong>Fig. 3</strong>:Uplifted tectonic of the Himalaya &ndash; Tibetan Plateau influence by erosion. a, Schematic paleogeographic cross-sections of the Himalaya and Tibetan Plateau modified from Neupane et al. (2017); MCT, Main Central Thrust; GT, Gangdese thrust; STDS, South Tibetan Detachment System; GCB, Gangrinboche Conglomerates; TTS, Tanggula Thrust System; NKLF, North Kunlun Fault; SQF, South Qilian Mountain Fault; NQF, North Qilian Mountain Fault; MBT, Main Boundary Thrust; GCT, Great Counter-Thrust; MFT, Main Frontal Thrust. IGP, Sw, LH, GHS, THS refer to Indo Gangetic Plain, Siwalik, Lesser Himalaya, Grater Himalaya sequences, Tethyan Himalayan sequences. b, the uplifted grater Himalayan metamorphic rocks are experiences rapid erosion and removal of material at the southern margin of the Himalayan flank allows the movement of a channel of hot, weak ductile rock (pink regions). &nbsp; Therefore, an increase in temperature from 1 to 3<sup>0</sup> C for the rainfed basin, the increase in annual evaporation was computed to be about 6&ndash;18% for the rainfed basin and 13&ndash;35% for the snowfield basin. The adverse effect on river runoff is likely to affect the watersheds within the mountains that create the problems in lowland regions, which are heavily dependent on this mountain resource (Singh and Bengtsson, 2005). Because these systems are sensitive to climatic factors and are likely to have different vulnerability thresholds according to the species, the amplitude, and the rate of climatic change (Dale et al., 2001). The climatic model results (Zhisheng et la., 2001)suggested that the relatively large high-elevation area that we insert in the model in going from stage, presumably reflecting elevation changes that occurred no later than about 8 Myr ago, are sufficient to alter significantly the thermally forced circulation and establish strong continent-scale summer and winter monsoons and central Asian aridity.The channel-flow model (Whipple, 2009) suggest a number of key attributes of Himalayan geology; extrusion of the GHS by means of contemporaneous slip.&nbsp; Between the MCT and STD, the conditions and timing of metamorphism in the GHS and LHS and, the formation of the chain of gneiss domes north of the Himalaya (Fig. 3). The monsoon in Himalaya was well established in the Miocene (Huntington et al., 2006; Kroon et al., 1991) which indicate that vigorous glacial erosion in the higher and drier mountain peaks to the north was important: consistent with the argument above that vigorous glacial erosion may counterbalance the northward decline in precipitation through the Himalaya. A large number of glaciers now terminate on such slopes in a state of gravitational disequilibrium.Similarly, recent climate change impact in the Greater Himalayan region affected by several sectors. Hydrological cycle will be affected by the absence of snow and ice. Therefore, the current distribution, seasonality, and the amount of precipitation may experience significant changes in various geographical regions. The current evidence from the above review suggests that climate change affects the entire Himalayan region; temperature increases, shifts in ecosystems, and increased frequency and duration of extreme events. It will be significant changes in volumes and timing of river flows and freshwater sources.The complex geological structure, the rugged and steep topography, insufficient exposures, dense forests, and high altitude are a major problem in the Himalayas. There was not much research carried out the region and contains many research gap from East to west Himalaya. &nbsp; <strong>4. Conclusions and future works</strong> Although many field observation, experiments, and hypothesis (erosion-induced channel-flow hypothesis) existed, it is quite complicated to make arguments that erosional control of deformation rates and patterns is shown in the topography, geology and thermal history of the Himalayan regions.&nbsp; Erosion and deformation rate in the mountain system have arisen in the scope of studies aiming to test the hypothesis that climate can significantly influence the tectonic and structural evolution of mountain ranges.The measurable climate parameters and erosional efficiency relation should be studied well. The above results and models related to tectonic&ndash;surface process predict that the tectonic and structural evolution of a mountain belt is sensitive to spatial and temporal variations in erosional efficiency. The erosional efficiency is directly linked with precipitation, whenever this link has been quantitatively established can the assessment of spatial correlations between climate and deformation rates and patterns move beyond speculation.There are several basins located tectonically active mountain fronts which are overfilled by sediments detritus, where precipitation and erosion play the major role for sedimentation in the regions where erosion controls the tectonics.Different drainage basin asymmetry of the Himalaya suggests tilting, active upliftment, and dynamic incision. Glacier is the most important part of the Greater Himalayan regions. Recently, the global warming effect shown in the period of glaciations, affect the nature of environmental change and the landscape evolution in the mountains of Central Asia. It shows the essential relations between climate change and glaciation in the Himalaya. The rate of accumulation of glaciers is less than the rate of retreat, effects on the South Asian summer monsoon system. The historical records of glacier fluctuations in the Himalayas and Trans-Himalayas extend back over 150 years. Recent deglaciation triggered the Catastrophic events consist of ice avalanches, landslides and slope instability caused by debuttressing, and outburst floods from moraine- and glacier-dammed lakes. To addressing the research gaps, we recommend, more widespread and long-term tracking of glacial ice volumes, studying the paleoclimate for greater Himalayan regions, further work is required to synthesize a set of testable hypotheses to guide field evaluation of the potential role of climate and erosion in shaping the evolution of such systems. <strong>Acknowledgments </strong> We would like to thanks a number of scientists whose work we have referenced here. This study was funded by the National Natural Science Foundation of China (Grant No.41661144026), and the major program of the National Natural Science Foundation of China (Grant No. 41490611).
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Patti-Signorelli, Anna, and José Javier Romero-Díaz de la Guardia. "CHAPTER 4: The biopsychosocial model and what it means for understanding inclusion in education - Brahm Norwich Introduction This chapter focuses on two specific pieces of Paul Cooper’s writing from 19 and 15 years ago respectively, namely his ideas about the biopsychosocial model and how he developed and used this perspective in unique ways to expand our thinking about inclusion and inclusive education. I believe this will give me the opportunity to show the detail of his analyses and way he engaged in the key debates going on in the field. It will also enable me to show the continuing relevance /of the arguments he voiced to current issues and concerns. Paul’s intellectual approach has been to oppose what he sees as false oppositions or dichotomies and this is something I have learned from and shared with him. The biopsychosocial model was for him a way to combine and bring together a more complex synthesis not just as an intellectual exercise, but as critical to enhancing educational practice, especially for those with disability and difficulties. A critical discussion of education, ADHD and the biopsychosocial (BPS) perspective Paul Cooper’s paper on the biopsychosocial perspective (Cooper, 2008) focuses on ADHD to propose a BPS model or what is called here a ‘paradigm’ as a way forward to address controversies amongst educationalists. Its argument had and continues to have much wider significance for the field of special educational needs and inclusive education. The main point in the paper was to show how the polarity between biological and social explanations for learning and behaviour problems had become redundant and unhelpful. ADHD it was stated was influenced by both biology and the social environment and indeed was ‘socially constructed’. But, this notion of social construction was not like the one adopted by the social model advocates referenced in the paper and still widely used in the 2020s. Shakespeare (2018, p. 68), for example, refers to the social model of disability as ‘the idea that people are disabled by society, rather than by their bodies’. What motivated Paul was the negativity towards the ADHD concept based on what he saw as: ‘outdated thinking and a lack of understanding of the diagnosis and the biopsychosocial paradigm through which it can be usefully understood’ (p. 457). Before examining the arguments about a social or a BPS model of ADHD, it worth exploring the usage of the terms in these models in written publications generally and in relation to academic research publications in education. Using the google ngram viewer system shows that the phrase ’social model of disability’ is used 114 times more in those texts covered within the google system than the phrase ‘biopsychosocial model of disability’ published in 2019. In addition, references to the phrase ‘social model of disability; increased 2.6 times from 2000 to 2019. By contrast, the use of the phrase ‘biopsychosocial model of disability’ increased more rapidly by 9.3 times, over the same period. Though this analysis is confined to those ngram accessed books in English, it does show that the ‘social model’ was used in this corpus considerably more than the ‘BPS model’. This is so even when the ‘BPS model’ had a greater increase in usage compared to the ‘social model’ over this almost two decade period. This picture is repeated when examining research literature references in education using the Education Research Complete database (ERC). In a search for literature with the terms ‘inclusive education or inclusion or mainstreaming or integration’ and either ‘biopsychosocial model’ or ‘social model’, it was found that there were 13 times as many references for social model than BPS model. It is clear from these analyses that Paul Cooper’s position has not been widely adopted since the 2000s and into the late 2010s, despite the international interest in the WHO International Classification of Functioning (ICF), which adopts a BPS model of disability (Hollenweger, 2012). My argument here is that this does not detract from the value and importance of the arguments in his paper. I am not going into the details of the case for the usefulness and risks in the use of medical classification systems that include ADHD as the most prevalent of childhood behaviour disorders. Cooper’s 2008 paper does this, and no doubt since then the current state of knowledge about ADHD has changed. What I will focus on is the argument made by Paul Cooper about the involvement of biological processes in functioning that comes to be identified as ADHD. Here he considered evidence for there being a problem in the response inhibition system, involving neuropsychological executive functioning mechanisms implicating physiological processes in the frontal lobes of the brain. In addition, he also implicates the genetic studies that have shown a much greater incidence of ADHD among identical than non-identical twins and among children who are biologically related as opposed to adopted. What he resists is the polarising between recognising these biological processes on human behaviour and the social processes; the either – or in favour of the both – and perspective. This is a central point in the commentary I am making of Paul Cooper’s positions and one which will be made too in relation to his ideas about inclusion in education below. The BPS model he is advocating rejects a biological determinism and represents biological factors as being mediated by psychosocial processes; the biological is subjected to social construction at various social and psychological levels. See Figure 4.1 which represents this kind of BPS model. In this respect the BPS model he advocates has strong links to Bronfenbrenner’s bio-ecological model (Bronfenbrenner and Morris, 2006). It is notable that many references to Bronfenbrenner’s ecological model have tended to also split the biological from the psycho-social (Tudge et al., 2009). Figure 4.1 Factors in interaction in the bio-psycho-social model of ADHD Critical reactions to ADHD have involved the dismissal of ADHD by some as a medical construct that individualises educational failure and disruptive behaviour. Part of the aversion to ADHD has been its use to legitimise the practice of using drugs as a form of social control of defiant children. Some argued this approach represented wrong-headed pseudo-science. The argument which Paul Cooper focussed on was the assertion that this individualised these problems, distract from how schools and teachers were involved in these problems, and so absolve them of responsibility to provide relevant opportunities for these groups. He countered this argument by claiming that the BPS model recognises that schools are a major setting through which institutional control and pedagogical practices contribute to the construction of ADHD. In his argument for a more complex BPS model, he countered the arguments of authors like Slee (1995) who were critical of what they portrayed as: ‘The monism of locating the nature of [classroom] disruption in the neurological infrastructure of the child is myopic and convenient’ (Slee, 1995, p. 74). Slee has continued this critical line of argument with his more recent views about the language of special educational needs in referring to: ‘the saturation of our discourse and thinking with the quasi-medical posturing of special educational needs. The conceptual foundations and usage of terms like special educational needs passes without a second thought’ (Slee, 2018; p. 78). Paul Cooper’s thorough response to four challenges from the critical perspective continue to be very relevant to the current circumstances. Firstly, it has been claimed that the ADHD diagnosis is somehow bogus or ‘illicit’ because there is an absence of neuro-scientific evidence. In this article he illustrates how this is ‘patently untrue’ (p. 463). Secondly, ADHD is sometimes claimed to be an example of biological determinism, a claim which expresses a fear of determinism and its associated denial of human agency. Here he has sympathy with this fear but shows how this is not well founded as regards developmental opportunities, given the interaction between biological inheritance and environmental factors in the development of behavioural difficulties. Paul Cooper argued that not only were there several biological pathways implicated in the development of ADHD, but that ADHD is not biologically determined in the simplistic sense suggested by some; see the Slee quote above. He turns the argument by ADHD critics about ADHD diverting attention from school factors against their position. He suggests that portraying ADHD as an example of biological determinism, itself diverts attention from converting a biopsychosocial account of ADHD into pedagogical and other interventions. By knowing more about the biological, psychological and social factors in ADHD enables us, he argued, to avoid aggravating experienced difficulties and promoting educational engagement. The third challenge he addressed was that an ADHD ‘diagnosis’ rests on value-laden, culturally-specific judgements about behavioural or cognitive norms. Here Paul Cooper adopts a perspective, not often found in debates about behaviour difficulties and school education norms. He recognised that children who are biologically predisposed to develop ADHD can be at a disadvantage by culturally based assumptions about appropriate school and classroom behaviour. But, this, he argues, does not reflect on the clinicians who identify ADHD, but reflects on the weaknesses of, what he called, ‘Western mass education’. This issue is about whether to change the educational environment to accommodate the student or to change the student to enable him or her to engage with an unchanging environment. As Paul Cooper recognised the attempt is often made to combine environmental and individual changes. He suggested that using medication can be seen as the failure of the school to make changes that enable the student with ADHD to engage effectively. The implications for those wanting to make schools more inclusive is to learn the lesson that ADHD teaches about shaping the educational environment to improve learning opportunities. In discussing how he approached this challenge, it is also notable that some psychologists have adopted more recently a BPS model of ADHD and supplemented the social aspects with a focus on the cultural aspects that relate to the mental health needs of culturally and linguistically diverse children and young people (Pham, 2015). The fourth challenge Paul Cooper responded to was that accepting an ADHD diagnosis ‘legitimise[s] the practice of drugging defiant children into docility’ (Skidmore, 2004, p. 4). To this he points out that informed opinion does not consider medication for ADHD as an essential treatment, and that whatever is decided is to be in the context of a multi-modal treatment programme that includes psychosocial and educational interventions. In his paper he refers to the UK guidance from 2000 and this is still the current guidelines (NICE, 2018). How parents participate in intervention selection is also illustrated in Pham (2015). The linked and final challenge he dealt with was that ADHD represents the wrongful medicalisation of defiance in school children. Here Paul Cooper questioned the link between defiance and the functional issues associated with ADHD. He suggested that defiance is better considered as a cognitive distortion affecting social engagement rather than a deficit in executive functioning associated with ADHD. So, not complying with parent wishes is seen as non-volitional and not to be confused with defiance. For him what was concerning was the ‘high moral tone’ (p. 470) which concealed limited understanding about ADHD that he believed could be dangerous. A crucial difference between the social and BPS models In defending the BPS model from critical arguments, Paul Cooper did not examine the ideological or value basis for the knowledge claims in these debates. From a critical perspective, it has been suggested by Slee & Weiner (2001) that it is possible to identify two groups of researchers, which they characterise in these terms, namely those who work within, what they call the ‘positivist paradigm’, accept the way things are, attempt to make marginal reforms and who criticise ‘full inclusion’ as ideological; and those who see inclusive education as cultural politics and call for educational reconstruction. This distinction between a positivist / technical versus cultural political position can be aligned with one between an investigatory versus an emancipatory perspective to research about disability (Oliver, 1999). Oliver frames the research-as-investigation as the dominant form of social research which is unacceptable to oppressed groups, such as those with disabilities, who aim to collectively empower themselves. In this perspective the social model of disability expresses the emancipatory stance which is pursued through cultural politics. This contrasts with a technical – interventionist perspective that derives from what Slee and Weiner (2001) call a ‘positivist paradigm’ and is associated with what is called a medical or a bio-medical model. It can be seen that this dichotomy between research stances embraces the splitting which Paul Cooper argued against. Figure 4.2 below represents these distinct research stances as adopting emancipatory or investigatory values, while showing their main focus and linked assumptions. With emancipatory values the main focus is on reducing the oppression of the vulnerable with this being done through collective socio-political action and in doing so entailing a causal assumption that it is the dominant social system that oppresses. With investigatory values, the main focus is on identifying complex causal models of a phenomenon and in doing so assumes that this knowledge can be used for subsequent improvement interventions. Figure 4.2 Value bases underlying different research stances One of the main arguments in this chapter is that there are links and common elements to these two basic value positions, so raising questions about the split and opposition between them. Both connect knowledge with action for social change, on one hand, and both assume some causal processes, on the other. The difference is in the assumptions of their main focus. Identifying complex causal processes (e.g. that includes social processes as part of a BPS perspective) is the primary focus of the investigatory stance, while change depends on applying this knowledge in interventions. This stance represents an outsider-spectator-intervenor perspective. By contrast, reducing the oppression of the vulnerable is the primary focus of the emancipatory stance, with this being through collective political and social action. This stance represents an insider-participator perspective. So, while distinct, there are connections to be recognised between them which can help to understand what the social stands for in these two models. The social in the social model stands for where change is to be focussed; in the socio-political arena. The social, by contrast, in the BPS model stands for the social factors that need to be understood in their interaction with bio-psychological causal factors. Making use of the distinction between insider-outsider role perspectives enables us to see how these different value stances can be connected and not seen as opposites to select between. As Paul Cooper argued in his 2008 paper, informed opinion does not consider medication for ADHD as an essential treatment / intervention; the BPS model implies multi-modal methods including psychosocial and educational interventions (NICE, 2018). Intervention / treatment acceptability is also an important consideration when considering individual children with identified ADHD from a BPS perspective, as illustrated in Pham’s (2015) case study. This implies that parents and young people will participate in action decisions, which gives them an insider role. However, the social model goes beyond insider participation at the individual level, to involve collective participation at institutional and societal levels too. This is where the BPS model could be open to insider participation beyond the individual level, to see the value of institutional and societal participation too. And, as the BPS can be open to the collective action of the social model, so the social model can be open to the outsider perspective’s recognition of multi-level causal processes (including the bio-psychological levels) and their associated interventions. Inclusion as a buzz-word In this 2008 paper Paul Cooper suggested that the use of insights from the BPS model in developing educational provision is likely to lead to a more genuinely inclusive education system. This was written after an earlier editorial he wrote in the journal Emotional and Behavioural Difficulties in 2004 (Cooper, 2004). Here he pointed to the overuse and misuse of the word inclusion, suggesting that it will lose its meaning and that the purposes for which it was coined will become neglected. One way of challenging this misuse, he mentioned, was to be vigilant about how it is used and to call for greater clarity. In this editorial he stated that social inclusion is about active participation and engagement with other people. With inclusive education, he continued, it is not just about social inclusion, but an individual’s active engagement in formal learning processes. Here Paul Cooper goes beyond common ideas about inclusion which are defined in terms of social and academic participation (as in the Inclusion Index; Booth and Ainscow, 2011), by clarifying that it is also about academic and social engagement. From this it was clear that inclusion was more than both location / placement and social interaction with other people; it was also about personal engagement with others and with formal learning. Paul Cooper was not alone in linking engagement with inclusion, he shared this with Mary Warnock, the chair of the Warnock Committee which in 1978 set out new policies about the education of children and young people with disabilities and difficulties (Warnock, 2005). In her 2005 policy paper she rejected the idea of educational inclusion as about ‘all children under the same roof’. She preferred a learning concept of inclusion, which was about: ‘including all children in the common educational enterprise of learning, wherever they learn best’ (Warnock, 2005). Though she does not use the term ‘engagement’ as such, her notion of learning where done best connects with ‘engagement’ and prioritises this over placement, a view which was also adopted later by Paul for the area of education of children and young people with social, emotional and behaviour difficulties (Cooper and Jacobs, 2011). Paul Cooper drew on the psychological ideas of Marjorie Boxall in the Boxall Profile (Bennathan and Boxall, 2003) to connect Inclusion with engagement, as he mentioned in his 2004 editorial. For him engagement was at the heart of educational inclusion from a cognitive perspective. He adopted the five subskills of what the Boxall Profile termed ‘the organization of experience’: whether the child gives purposeful attention, participates constructively, connects up experiences, shows insightful involvement and engages cognitively with peers. Within this framework he recognised that children with social, emotional and behavioural difficulties (SEBD) can have problems with some or all of these skills. So, it can be argued that the child who experiences SEBD is socially, emotionally and cognitively excluded from what is going in class lessons; with SEBD being framed as a barrier to inclusion. This concept of a barrier is very different to that proposed from a social model perspective as in the Inclusion Index (Booth and Ainscow, 2011), in which barriers are only external to the person. But, Paul Cooper does not draw the conclusion that children with SEBD can never be ‘included’. Here he makes the distinction between inclusion-as-location and inclusion-as-engagement, with the implication that in some cases when there is not mainstream class inclusion this does not mean there cannot be some engagement inclusion. He also reminded us that inclusion is such that nobody is ever fully included in any situation all the time. In this sense his ideas resemble Qvortrup and Qvortrup’s (2018) argument that inclusion and exclusion are connected through peoples’ simultaneous involvement in different social arenas. With social interactions involving negotiations in all situations, Paul Cooper argued that any episode can result in tensions and the rejection of the people involved . This is a feature of our lives and in this respect the child experiencing SEBD is no different from others. However, he pointed out that the child or young person with a SEBD is at greater risk of rejection or exclusion, which may be attributed to individual characteristics in interaction with social circumstances (in line with a BPS model). Using this notion of engagement, he also approached the questions of teaching children and young people with SEBD in terms of the BPS model. In avoiding a focus just on problems located in the student, he adopted an interactionist perspective that combined specialist teaching knowledge about individual differences with teachers’ practical thinking about decision-making that led to adapted teaching (Cooper, 2004). He reviewed in this 2004 chapter and in his later 2008 paper discussed above, the various teaching strategies that research had shown to promote further engagement for children with ADHD. It is useful here to compare his engagement perspective to a well-known ‘Inclusive Pedagogy (IP) framework for participation in classrooms’ developed by Florian and Black-Hawkins (2011). This framework in covering access, collaboration, achievement and diversity aimed to extend what was typically available in the classroom community to all. It avoided having learning activities for most being alongside different activities for some who experience difficulties. It also proposed differentiation by pupil choice for everyone while rejecting ability grouping. This is an approach that required flexibility to be driven by need and not curriculum coverage, while seeing difficulties in learning as professional challenges rather than learner deficits. Though Paul Cooper’s perspective agreed with some elements of this inclusive pedagogy framework (e.g. flexibility and responding to learning difficulties as a challenge), his does not accept the either-or polarity at the core of the framework with the adoption of only one option: differentiation by choice v. by grouping and only opting for the former, or seeing learning difficulties as a professional challenge v. learner deficits and opting only for the challenge option). This IP framework reflects the medical v social model polarity that he argued against while favouring a BPS model. Based on his approach of seeing social and academic engagement as being at the heart of educational and social inclusion, he believed that it followed that: ‘students are best placed in educational settings where they have access to and support for maximum social and academic engagement’. (Cooper, 2004, p. 222). In his view, this meant that there was no simple way to decide about the provision setting. For some pupils this meant access to various forms of provision, but always a detailed analysis of individual capabilities and needs as well as what provision affords should determine the decisions. Conclusion This chapter has focussed on two of Paul Cooper’s papers in which he explained and justified his ideas about the biopsychosocial model and how he developed and used this perspective in unique ways to expand our thinking about inclusion and inclusive education. Through relating and contrasting these with other contemporary and current ideas I hope to have shown his distinctive and insightful contribution. I have also tried to extend his adoption of a both-and rather than an either-or approach by discussing the epistemological and value bases of different models, on one hand, and how difference and distinction does not imply irreconcilable opposition between the key models in the field. References: Bennathan, M. & Boxall, M. (2003) The Boxall Profile. East Sutton: SEBDA. Booth, T. and Ainscow, M. (2011) Index for Inclusion: developing learning and participation in schools. 3rd ed. Bristol: CSIE. Bronfenbrenner, U., and Morris, P. (2006) The bioecological model of human development. In W. Damon & R. M. Lerner (Eds.), Handbook of child psychology: Vol. 1. Theoretical models of human development (6th ed., pp. 793–828). Hoboken, NJ: Wiley. Cooper, P. (2004) Is ‘inclusion’ just a buzz-word?, Emotional and Behavioural Difficulties, 9:4, 219-222, DOI: 10.1177/1363275204051391 Cooper, P. (2004) ‘AD/HD’, in A. Lewis & B. Norwich (eds) Special Teaching for Special Children? Pedagogies for Inclusion. Buckingham: Open University Press. Cooper, P. (2008) Like Alligators Bobbing for Poodles? A Critical Discussion of Education, ADHD and the Biopsychosocial Perspective. Journal of Philosophy of Education, 42, 3-4, 457-474. Cooper, P. and Jacobs, B. (2011) From Inclusion to Engagement: Helping Students Engage with Schooling Through Policy and Practice. London: Wiley. Florian, L. and Black-Hawkins, K. (2011) Exploring inclusive pedagogy, British Educational Research Journal, 37, 5, pp. 813-828. Hollenweger, J. (2012) Using the International Classification of Functioning, Disability and health Children and Youth version in education systems. American Journal of Physical Medicine and Rehabilitation, 91, 13, pp. 97-102. NICE (2018) Attention deficit hyperactivity disorder: diagnosis and management NICE guidelines. Published: 14 March 2018. Access on 23.5.23 www.nice.org.uk/guidance/ng87 Oliver, M. (1999) Final accounts and the parasite people. in Corker, M. and French, S. (eds.) Disability discourse. (eds.) Maidenhead: Open University Press. Pham, A.V. (2015) Understanding ADHD from a Biopsychosocial-Cultural Framework: A Case Study. Contemporary School Psychology, 19:54–62. Qvortrup, A. and Qvortrup, L. (2018). Inclusion: Dimensions of inclusion in education. International Journal of Inclusive Education, 22(7), 803-817. Shakespeare, T. (2018) Disability: the basics. London: Routledge. Skidmore, D. (2004) Inclusion. Buckingham,: Open University Press. Slee, R. (1995) Changing Theories and Practices of Discipline. London, Falmer. Slee, R. and Weiner, G. (2001). Education Reform and Reconstruction as a Challenge to Research Genres: Reconsidering School Effectiveness Research and Inclusive Schooling. School Effectiveness and School Improvement, 12:1, 83-98, DOI: 10.1076/sesi.12.1.83.3463 Slee, R. (2018) Inclusive Education isn’t Dead, it Just Smells Funny. London: Routledge. Tudge, J.R.H., Mokrova, I., Hatfield, B.E. and Karnik, R.B. (2009) Uses and Misuses of Bronfenbrenner’s Bioecological Theory of Human Development. Journal of Family Theory & Review, 1, 198–210. Warnock, M. (2005) Special Educational Needs: A New Look. London: Philosophy of Education Society of Great Britain, Impact Series No. 11." International Journal of Emotional Education 15, no. 2 (2023). http://dx.doi.org/10.56300/esja4186.

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The present study aimed to determine the emotional characteristics of the Trait-Meta-Mood-Scale (TMMS-24) in music-oriented secondary school students in Italy. A 24-item self-assessment protocol was applied to measure the level of perceived emotional intelligence according to 3 dimensions: attention, clarity and repair. This tool represents one of the most widely used self-assessment measures of perceived emotional intelligence. The objective of the study was to conduct construct validation to examine reliability of the Italian version of the TMMS-24 in order to identify its feasibility for the assessment of emotional intelligence. Exploratory and confirmatory factorial analyses were conducted on a sample of music-oriented secondary school students in Italy (n=402). Exploratory factor analysis outcomes revealed that the three dimensions of the original scale (attention, clarity and emotional repair) are supported in the examined context, showing adequate internal consistency and describing 52.6% of overall variance. Outcomes were confirmed via confirmatory analysis, obtaining good fit indices (CFI=0.986; TLI=0.985; RMSEA=0.038). The TMMS-24 scale is a valid and reliable instrument for measuring the emotional intelligence of secondary school students in Italy. Keywords: TMMS-24, emotional intelligence, secondary school education, exploratory factor analysis, confirmatory factor analysis.
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