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1

Fendl, Monika. "Report on the research stay in the USA 26 February - 21 May 2001." Thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2004. http://nbn-resolving.de/urn:nbn:de:swb:14-1080550789843-16201.

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Skorupa, Wolfgang, and Gerhard Brauer. "HeT-SiC-05International Topical Workshop on Heteroepitaxy of 3C-SiC on Silicon and its Application to Sensor DevicesApril 26 to May 1, 2005,Hotel Erbgericht Krippen / Germany- Selected Contributions -." Forschungszentrum Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-28591.

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This report collects selected outstanding scientific and technological results obtained within the frame of the European project "FLASiC" (Flash LAmp Supported Deposition of 3C-SiC) but also other work performed in adjacent fields. Goal of the project was the production of large-area epitaxial 3C-SiC layers grown on Si, where in an early stage of SiC deposition the SiC/Si interface is rigorously improved by energetic electromagnetic radiation from purpose-built flash lamp equipment developed at Forschungszentrum Rossendorf. Background of this work is the challenging task for areas like microelectronics, biotechnology, or biomedicine to meet the growing demands for high-quality electronic sensors to work at high temperatures and under extreme environmental conditions. First results in continuation of the project work – for example, the deposition of the topical semiconductor material zinc oxide (ZnO) on epitaxial 3C-SiC/Si layers – are reported too.
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Skorupa, Wolfgang, and Gerhard Brauer. "HeT-SiC-05International Topical Workshop on Heteroepitaxy of 3C-SiC on Silicon and its Application to Sensor DevicesApril 26 to May 1, 2005,Hotel Erbgericht Krippen / Germany- Selected Contributions -." Forschungszentrum Rossendorf, 2005. https://hzdr.qucosa.de/id/qucosa%3A21685.

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This report collects selected outstanding scientific and technological results obtained within the frame of the European project "FLASiC" (Flash LAmp Supported Deposition of 3C-SiC) but also other work performed in adjacent fields. Goal of the project was the production of large-area epitaxial 3C-SiC layers grown on Si, where in an early stage of SiC deposition the SiC/Si interface is rigorously improved by energetic electromagnetic radiation from purpose-built flash lamp equipment developed at Forschungszentrum Rossendorf. Background of this work is the challenging task for areas like microelectronics, biotechnology, or biomedicine to meet the growing demands for high-quality electronic sensors to work at high temperatures and under extreme environmental conditions. First results in continuation of the project work – for example, the deposition of the topical semiconductor material zinc oxide (ZnO) on epitaxial 3C-SiC/Si layers – are reported too.
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4

Stinton, Diane Barbara. "Luke 1:26-56 an exegetical study of biblical spirituality as exemplified in Mary of Nazareth /." Theological Research Exchange Network (TREN), 1994. http://www.tren.com.

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5

Steiger, Kirsten Rachelle. "Crosses, Flowers, and Toads: Classic Maya Bloodletting Iconography in Yaxchilan Lintels 24, 25, and 26." BYU ScholarsArchive, 2010. https://scholarsarchive.byu.edu/etd/2244.

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The lintels of Yaxchilan Structure 23 seem to be a demonstrable case wherein specific symbols are singled out and deliberately used in an ordered sequence. Taken together as a unified series, Yaxchilan Lintels 24, 25, and 26 summarize the multi-step process of royal autosacrifice. An iconographic study of the huipil patterns depicted on these lintels yields a better understanding of complex bloodletting iconography and the way in which depictions of ceremonial autosacrifice reinforce Classic Maya beliefs relating to the divine role of Maya elite in eliciting communion with the gods and the subsequent rebirth of the cosmos. The rich iconography of the lintels gives depth to our understanding of importance of royal bloodletting on a cosmic level. Their detailed imagery clarifies what seems to have occurred during each step of the ritual process. The events and symbolism depicted on the three lintels build from each other to form a unified iconographic whole centered on the rebirth of the gods and the cosmos through royal autosacrifice. Iconographic changes from one lintel to the next communicate the pervasiveness of cycles of death and rebirth in Classic Maya cosmology. The symbolism of each lintel communicates the interrelatedness of death and rebirth, while underscoring the role of the ruler in initiating cosmic renewal through autosacrifice. As Yaxchilan Lintels 24, 25, and 26 present themselves in an interrelated series, the subtle differences within the iconography from one lintel to the next represent important progressions within cycles of death and rebirth, elucidating the significance of certain steps within the royal bloodletting ritual and the cosmic rebirth that takes place as a result. As a set, the combined iconographies present on the queen's huipil—crosses, flowers, and toads—epitomize the objective of the ritual, namely rebirthing the cosmos and the gods through the sacrifice of divine blood.
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von, Sachsen Moritz. "Politische Korrespondenz des Herzogs und Kurfürsten Moritz von Sachsen / Vierter Band : 26. Mai 1548 – 8. Januar 1551." Akademie Verlag, 1992. https://slub.qucosa.de/id/qucosa%3A16281.

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Herzog Moritz (1521–1553), seit 1547 erster albertinischer Kurfürst von Sachsen, war einer der bedeutendsten Reichsfürsten und Politiker im 16. Jahrhundert. Unter seiner Regierung wurde das albertinische Kurfürstentum Sachsen zur wichtigsten Macht in der Reichspolitik neben den Habsburgern. Durch seine Politik, die ihn zunächst auf die Seite Kaiser Karls V. gegen den Schmalkaldischen Bund, dann aber im Bündnis mit Frankreich an die Spitze der Opposition gegen Kaiser führte, ist Moritz zugleich eine der umstrittensten Persönlichkeiten der deutschen Geschichte des 16. Jahrhunderts. Moritz suchte einerseits Sicherheit für sein Land und seine eigene Position, zugleich verfolgte er weitreichende reichspolitische Ziele – die Aufhebung des Interims von 1548, Sicherheit und Gleichberechtigung für die Anhänger der Augsburgischen Konfession, die Verhinderung einer „Universalmonarchie“ des Kaisers und die Errichtung einer allgemeinen Friedensordnung im Reich. Er bahnte den Weg zum Augsburger Religionsfrieden von 1555, der Deutschland eine der längsten Friedensperioden seiner Geschichte sicherte. Mit der Veröffentlichung zahlreicher – zumeist bisher ungedruckter – Quellen aus mehr als 45 deutschen und europäischen Archiven zeigt die Edition die Bedeutung des Kurfürsten für die Landes- wie für die Reichsgeschichte. Die sechs Bände enthalten insgesamt 4295 Dokumente sowie über 5000 weitere Aktenstücke, die jenen nach sachlichen Gesichtspunkten zugeordnet sind. Nachdem die Bände 1 und 2 bereits 1900 und 1904 erschienen sind, wurde die Edition ab Band 3 (erschienen 1978) als Projekt der Sächsischen Akademie der Wissenschaften zu Leipzig fortgesetzt. Band 4 der Politischen Korrespondenz der Herzogs und Kurfürsten Moritz von Sachsen enthält die Dokumente der Zeit vom 26. Mai 1548 bis zum 8. Januar 1551. Herausragende Ereignisse sind die Auseinandersetzungen um das Augsburger Interim Karls. V., der Leipziger Landtag im Dezember 1548 und seine Religionsartikel (sog. 'Leipziger Interim'), die Bemühungen um die Freilassung Landgraf Philipps von Hessen aus kaiserlicher Haft, der Beginn der Belagerung der Stadt Magdeburg sowie die Beteiligung von Moritz an Bündnisverhandlungen gegen Kaiser Karl V. und seine Verbindungsaufnahme mit Frankreich. Der Band enthält 820 Dokumente sowie ca. 1500 weitere Aktenstücke, die jenen nach sachlichen Gesichtspunkten zugeordnet sind. Veröffentlicht wurde dieser Band in der Reihe „Abhandlungen der Sächsischen Akademie der Wissenschaften zu Leipzig, Philologisch-historische Klasse“ als Band 72.:siehe Sekundärdatei 'Inhaltsverzeichnis (PDF) MVS-4'
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Bernard, Amaury. "Une guerre en suspens, 26 août 1939-10 mai 1940 : quand les combattants allemands, britanniques et français attendaient." Thesis, Paris 10, 2019. http://faraway.parisnanterre.fr/login?url=http://bdr.parisnanterre.fr/theses/intranet/2019/2019PA100100/2019PA100100.pdf.

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« Sitzkrieg », « Phoney war » et « Drôle de guerre » sont habituellement les termes employés pour qualifier la période du 1er septembre 1939 au 10 mai 1940, marquée par l’absence de combat et l’ennui au front. Pourtant, ces termes cachent voire essentialisent un temps plus complexe, où mémoires de la Grande Guerre et modernités du combat s’entremêlent. La comparaison des combattants allemands, britanniques et français depuis leur mobilisation – le 26 août 1939 pour les Allemands – jusqu’au déclenchement de la campagne à l’Ouest, permet de mettre en lumière cette période trop souvent oubliée.A partir des journaux du front, des journaux intimes, des lettres et des carnets de guerre des soldats, mais également d’archives officielles, cette thèse s’interroge la manière dont la guerre qui s’installe au cours de la période du 1er septembre 1939 et le 10 mai 1940, par son originalité et son caractère atypique transforme les représentations des combattants allemands, britanniques et français.Cette thèse s’est attachée à montrer que cette guerre en suspens se définit tout d’abord par l’expectative du combat. Les mois d’attente sont pour eux une période d’apprentissage ou de réapprentissage du métier de soldat. De plus, Cette thèse voulait également montrer que dans les trois armées, existe une remise en question de l’identité propre aux combattants. Il s’agit de retrouver une légitimité, une signification à leur place, à leur rôle dans cette guerre où ils ne peuvent remplir leur fonction première, celle de combattre
"Sitzkrieg", "Phoney war" and "Drôle de guerre" are usually the terms used to describe the period from September 1st, 1939 to May 10th, 1940, marked by the absence of combat and boredom at the front. However, these terms conceal or even essentialize a more complex time, when memories of the Great War and the modernities of combat were intertwined. The comparison of German, British and French combatants from their mobilization - on 26 August 1939 for the Germans - to the launching of the campaign in the West, highlights this all too often forgotten period.Based on the front journals, diaries, letters and war diaries of the soldiers, but also official archives, this thesis questions the way in which the war that took place during the period from from September 1st, 1939 to May 10th, 1940, by its originality and atypical character, transformed the representations of German, British and French soldiers.This thesis has focused on showing that this pending war is defined first of all by the expectation of combat. The waiting months are for them a period of apprenticeship or relearning of the soldier's trade. This thesis then wanted to show that in all three armies, there is a questioning of the identity specific to combatants. It is a question of rediscovering a legitimacy, a meaning in their place, in their role in this war where they cannot fulfil their primary function, that of fighting
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8

Felisiak, Michaela [Verfasser]. "Regulierungsbedarf grenzüberschreitender Betriebsübergänge : Zweifel an der grenzüberschreitenden Anwendbarkeit des § 613a BGB. (Urteil des BAG vom 26. Mai 2011) / Michaela Felisiak." Frankfurt : Peter Lang GmbH, Internationaler Verlag der Wissenschaften, 2015. http://d-nb.info/1080457534/34.

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9

Poggiali, Davide. "Postprocessing Neuroimaging methods in MRI and PET/MRI with applications to Multiple Sclerosis and other Neurological diseases." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3421919.

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Many non-invasive imaging instruments have been developed in the last 40 years, allowing to obtain images of the interior human body while the patient is still alive. In the contest of Neurology studies, imaging system as CT, MRI, SPECT or PET allows to obtain biomarkers useful to quantitatively distinguish between healthy and unhealthy subjects, evaluate the staging of a Neurological illness in a patient, evaluate the efficacy of a treatment, explore the causes of the illness. In this work MRI and PET imaging system introduced from scratch, going from reconstruction from raw data to state-of-the art post-processing techniques and the computation of more popular biomarkers. After these introduction, three original work using the recent PET/MRI imaging system are presented, with a particular focus on the methods. These three studies involve patients with Multiple Sclerosis, Alzheimer's Disease and Brain Tumor.
Negli ultimi 40 anni sono stati sviluppati diversi strumenti di imaging non-invasivi, in modo da ottenere immagini dell'interno del corpo umano mentre il paziente è ancora in vita. Nel contesto neurologico, sistemi di imaging come TAC, RM, SPECT e PET permettono di ottenere biomarcatori utili a distinguere quantitativamente soggetti sani da pazienti con malattie neurologiche, valutare lo stato di avanzamento di una malattia in un paziente, valutare l'efficacia di un trattamento, esplorare le cause della malattia. Nel presente lavoro si presentano i sistemi di acquisione di immagini RM e PET fin dalle fondamenta, partendo dai metodi di ricostruzione dell'immagine dai dati grezzi, allo stato dell'arte dei metodi di post-processing, fino al calcolo dei biomarcatori più diffusi. Dopo tale introduzione saranno presentati tre lavori originali di imaging PET/MRI, con una particolare attenzione ai metodi. Questi tre lavori riguardano pazienti con Sclerosi Multipla, Morbo di Alzheimer e Tumori Cerebrali.
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Pohlmann, Gabriele. "Therapie von Xenotransplantaten humaner gastrointestinaler Karzinome mit einer Kombination von intratumoraler Radioimmuntherapie (131 J-MAK BW 431/26) und systemischer Chemotherapie (Mitomycin C)." [S.l.] : [s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=964566869.

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11

Hedman, Magdalena. ""Hur skall detta ske? Jag har ju aldrig haft någon man." : Hur feministiskt exegetisk litteratur bidragit till förståelsen av Luk 1:26-38 åren 1977-2012." Thesis, Uppsala universitet, Teologiska institutionen, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-230697.

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12

Pitres, Albert. "Recherches sur les lésions du centre ovale des hémisphères cérébraux étudiées au point de vue des localisations cérébrales thèse pour le doctorat en médecine présentée et soutenue le 26 mai 1877 /." Paris : BIUM, 2003. http://www.bium.univ-paris5.fr/histmed/medica/cote?TPAR1877x201.

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13

Gault, Brian C. "The covenant of creation an exegetical and theological investigation of the image of God in Genesis 1:26-28 as the sign and seal of the covenant of creation, and of the covenant of works in Genesis 2:16-17 as the fourth stipulation of the covenant of creation /." Online full text .pdf document, available to Fuller patrons only, 2003. http://www.tren.com.

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14

Frini, Marouane. "Diagnostic des engrenages à base des indicateurs géométriques des signaux électriques triphasés." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSES052.

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Bien qu’ils soient largement utilisés dans le domaine, les mesures vibratoires classiques présentent plusieurs limites. A la base, l’analyse vibratoire ne peut identifier qu’environ 60% des défauts qui peuvent survenir dans les machines. Cependant, les principaux inconvénients des mesures de la vibration sont l’accès difficile au système de transmission afin d’y placer le capteur ainsi que le coût conséquent de la mise en œuvre. Ceci résulte en des problèmes de sensibilité relatifs à la position de l’installation et ceux de difficulté pour distinguer la source de vibration à cause de la diversité des excitations mécaniques qui existent dans l’environnement industriel.Par conséquent, l’analyse des signatures du courant électrique des moteurs s’impose comme une alternative prometteuse à l’analyse vibratoire et a donc fait l’objet d’une attention grandissante au cours des dernières années. En effet, l’analyse des signatures électriques a l’avantage d’être une méthode techniquement accessible, non-intrusive au système et peu coûteuse. Les techniques basées sur le courant et la tension ne requièrent que les mesures électriques du moteur qui sont souvent déjà surveillées pour le contrôle et la protection des machines électriques. Ce processus a été principalement utilisé pour la détection des défauts de moteur tels que la rupture de barres du rotor et les défauts d’excentricité ainsi que les défauts de roulements. En revanche, très peu de recherches concernent la détection des défauts en utilisant l’analyse du courant. En outre, les signaux électriques triphasés sont caractérisés par des représentations géométriques particulières liées à leur forme d’onde qui peuvent servir en tant qu’indicateurs différents offrant des informations supplémentaires. Parmi ces indicateurs géométriques, les transformées de Park et de Concordia modélisent les composantes électriques dans un repère bidimensionnel et toute déviation par rapport à la représentation d’origine indique l’apparition d’un dysfonctionnement. Aussi, les équations différentielles de Frenet-Serret représentent la trajectoire du signal dans un espace euclidien tridimensionnel et indiquent ainsi tout changement dans l’état du système. Bien qu’ils aient été utilisés pour les défauts de roulements, ces indicateurs n’ont pas été appliqués dans la détection des défauts d’engrenages en utilisant l’analyse des signatures des courants électriques. D’où l’idée novatrice de combiner ces indicateurs avec des techniques de traitement de signal, ainsi que des techniques de classification pour le diagnostic des engrenages en utilisant l’analyse des signatures de courant et de tension du moteur électrique.Ainsi, dans ce travail, on propose une nouvelle approche pour le diagnostic des défauts d’engrenages en utilisant l’analyse des courants et des tensions électriques du stator de la machine et ceci en se basant sur un ensemble d’indicateurs géométriques (Transformées de Park et de Concordia ainsi que les propriétés du repère Frenet-Serret). Ces indicateurs font partie d’une bibliothèque de signatures de défauts qui a été construite et qui comprend également les indicateurs classiques utilisés pour un large éventail de défauts. Ainsi, un algorithme combine les acquisitions expérimentales des signaux électriques à des méthodes de traitement de signal avancées (décomposition modale empirique,…). Ensuite, celui-ci sélectionne les indicateurs les plus pertinents au sein de la bibliothèque en se basant sur les algorithmes de sélection de paramètres (sélection séquentielle rétrograde et analyse des composantes principales). Enfin, cette sélection est utilisée pour la classification non-supervisée (K-moyennes) pour la distinction entre l’état sain et l’état défaillant
Although they are widely used, classical vibration measurements have several limitations. Vibration analysis can only identify about 60% of the defects that may occur in mechanical systems. However, the main drawbacks of vibration measurements are the difficult access to the transmission system in order to place the sensor as well as the consequent cost of implementation. This results in sensitivity problems relative to the position of the installation and the difficulty to distinguish the source of vibration because of the diversity of mechanical excitations that exist in the industrial environment.Hence, the Motor Current Signatures Analysis (M.C.S.A.) represents a promising alternative to the vibration analysis and has therefore been the subject of increasing attention in recent years. Indeed, the analysis of electrical signatures has the advantage of being a technically accessible method as well as inexpensive and non-intrusive to the system. Techniques based on currents and voltages only require the motor’s electrical measurements which are often already supervised for the purposes of the control and the protection of the electrical machines. This process was mainly used for the detection of motors faults such as rotor bars breakage and eccentricity faults as well as bearings defects. On the other hand, very little research has been focused on gear faults detection using the current analysis. In addition, three-phase electrical signals are characterized by specific geometric representations related to their waveforms and they can serve as different indicators providing additional information. Among these geometric indicators, the Park and Concordia transforms model the electrical components in a two-dimensional coordinate system and any deviation from the original representation indicates the apparition of a malfunction. Moreover, the differential equations of Frenet-Serret represent the trajectory of the signal in a three-dimensional euclidean space and thus indicate any changes in the state of the system. Although they have been previously used for bearing defects, these indicators have not been applied in the detection of gear defects using the analysis of electrical current signatures. Hence, the innovative idea of combining these indicators with signal processing techniques, as well as classification techniques for gears diagnosis using the three-phase motor’s electrical current signatures analysis is established.Hence, in this work, a new approach is proposed for gear faults diagnosis using the motor currents analysis, based on a set of geometric indicators (Park and Concordia transforms as well as the properties of the Frenet-Serret frame). These indicators are part of a specifically built fault signatures library and which also includes the classical indicators used for a wide range of faults. Thus, a proposed estimation algorithm combines experimental measurements of electrical signals with advanced signal processing methods (Empirical Mode Decomposition, ...). Next, it selects the most relevant indicators within the library based on feature selection algorithms (Sequential Backward Selection and Principal Component Analysis). Finally, this selection is combined with non-supervised classification (K-means) for the distinction between the healthy state and faulty states. It was finally validated with a an additional experimental configuration in different cases with gear faults, bearing faults and combined faults with various load levels
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Yan, Xiaowei. "Seismogenic mechanism of the May 26, 2003, northeastern Japan intermediate-depth earthquake." 2005. http://catalog.hathitrust.org/api/volumes/oclc/60707967.html.

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Thesis (M.S.)--University of Wisconsin--Madison, 2005.
Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 21-26)
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16

National, Science Board (NSB). "Long-Lived Digital Data Collections: Enabling Research and Education in the 21st Century: Report of the National Science Board (Pre-publication draft, Approved by the National Science Board May 26, 2005, subject to final editorial changes.)." 2005. http://hdl.handle.net/10150/105473.

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From the Executive Summary of the 67 page Report: The National Science Board (NSB, the Board) recognizes the growing importance of these digital data collections for research and education, their potential for broadening participation in research at all levels, the ever increasing National Science Foundation (NSF, the Foundation) investment in creating and maintaining the collections, and the rapid multiplication of collections with a potential for decades of curation. In response the Board formed the Long-lived Data Collections Task Force. The Board and the task force undertook an analysis of the policy issues relevant to long-lived digital data collections. This report provides the findings and recommendations arising from that analysis. The primary purpose of this report is to frame the issues and to begin a broad discourse. Specifically, the NSB and NSF working together â with each fulfilling its respective responsibilities â need to take stock of the current NSF policies that lead to Foundation funding of a large number of data collections with an indeterminate lifetime and to ask what deliberate strategies will best serve the multiple research and education communities. The analysis of policy issues in Chapter IV and the specific recommendations in Chapter V of this report provide a framework within which that shared goal can be pursued over the coming months. The broader discourse would be better served by interaction, cooperation, and coordination among the relevant agencies and communities at the national and international levels. Chapters II and III of this report, describing the fundamental elements of data collections and curation, provide a useful reference upon which interagency and international discussions can be undertaken. The Board recommends that the Office of Science and Technology Policy (OSTP) take the lead in initiating and coordinating these interagency and international discussions.
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"Man erntet, was man sät: Ziele für Nachhaltige Entwicklung, Schwerpunkt: Klima, Umwelt, Nachhaltigkeit - Tansania-Partnerschaftssonntag 'Rogate', 26. Mai 2019: Utavuna ulichopanda." Evangelisch-Lutherisches Missionswerk Leipzig, 2019. https://slub.qucosa.de/id/qucosa%3A35773.

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Marotta, Angela. "FOOLING THE SENSE OF TOUCH: NEW EVIDENCE ON THE ROLE OF BODY REPRESENTATIONS IN SHAPING SOMATIC PERCEPTION." Doctoral thesis, 2015. http://hdl.handle.net/11562/915003.

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Nella vita di tutti i giorni, capita numerose volte di toccare oggetti di diverso tipo con le mani. Il nostro cervello non è un ricevitore passivo di tali informazioni. Infatti, l'elaborazione degli input sensoriali coinvolge diverse rappresentazioni corporee che influiscono sul modo in cui percepiamo gli oggetti. Numerosi studi hanno dimostrato che l’elaborazione degli stimoli tattili avviene a diversi livelli. Un primo livello coinvolge le mappe somatotopiche, rappresentazioni stabili del corpo che non tengono conto dei cambiamenti posturali. Un secondo livello, coinvolge lo schema corporeo, una rappresentazione dinamica che si riadatta in base ai cambiamenti posturali. Questa tesi indaga il ruolo delle diverse rappresentazioni corporee nel modulare la percezione di stimoli innocui e dolorosi applicati sulle dita. Tali aspetti sono stati indagati attraverso due illusioni somatosensoriali: l’illusione di Aristotele e l’illusione della griglia termica. Nello specifico, il primo studio indaga i correlati percettivi delle alterazioni a carico della rappresentazioni somatotopiche delle dita e il modo in cui tali alterazioni possono influenzare la relazione funzionale tra più dita nella percezione tattile. Per tale scopo, abbiamo utilizzato l' illusione di Aristotele quale paradigma sperimentale e la distonia focale della mano come modello di rappresentazioni somatotopiche delle dita alterate. Tali alterazioni potrebbero riflettersi sulla relazione funzionale tra più dita nella percezione tattile. La distonia focale della mano, tuttavia, presenta disordini somatosensoriali comuni ad altre forme di distonia focale e alla malattia di Parkinson. Questo potrebbe essere dovuto ad una comune alterazione a carico dei gangli della base. Al fine di escludere ogni possibile ruolo dei gangli della base nel modulare l’illusione di Aristotele in pazienti con distonia focale della mano abbiamo condotto due esperimenti in cui i tali pazienti e quelli con altre forme di distonia focale e malattia di Parkinson sono stati confrontati rispetto a quanto percepissero o meno l’illusione di Aristotele. I risultati dei due esperimenti 1) confermano che la rappresentazione somatotopica delle dita è specificamente alterata nella distonia focale della mano, e 2) dimostrano che tale alterazione si associa ad un cambiamento nella relazione funzionale tra le dita nella percezione tattile specifica per la distonia focale della mano. Il secondo studio ha analizzato il ruolo dello schema corporeo nell’elaborazione di stimoli termo-tattili. L’obiettivo in questo caso era quello di studiare come l’organizzazione spaziale di diverse parti del corpo oggetto di stimolazione moduli l’illusione della griglia termica. Tale illusione è frequentemente utilizzata per studiare i fattori che influenzano la percezione del dolore. L’illusione della griglia termica deriva dall’applicare temperature calde e fredde innocue secondo uno specifico pattern caldo-freddo-caldo. Tale pattern di stimolazione determina che la temperatura fredda sia percepita come bollente. Nel nostro studio abbiamo utilizzato lo stesso pattern di stimolazione ma applicando ciascuna temperatura sull’indice, il medio e l’anulare. Incrociando o meno l’indice e il medio dei partecipanti, è emerso che la sensazione di caldo bruciante si riduceva quando il pattern spaziale delle temperature era freddo-caldo-caldo, indipendentemente che le dita fossero o meno incrociate. Tali risultati dimostrano come il cervello tenga conto della posizione relativa che ciascuno stimolo occupa rispetto agli altri nel definire la sensazione di calore doloroso evocato dall’illusione della griglia termica.
In everyday life, we use our hands to explore or manipulate objects. The processing of somatosensory inputs involves different representations of the body, and the resulting subjective experience of touch is strongly influenced by the type of body representation used for sensory processing. In the first instance tactile stimuli are processed within somatotopic maps that preserve the topographical organization of the physical body. Successively, the somatosensory inputs are further processed within the body schema which takes track of the postural changes of the body. In this framework, the current thesis is aimed at investigating the specific role of somatotopic maps and body schema in modulating the multi-digit tactile and thermo-tactile perception. This purpose has been achieved by “fooling” the sense of touch through two somatosensory illusions: Aristotle’s illusion and the Thermal Grill Illusion. In the first study we investigated the tactile processing occurring within the somatotopic maps. We approached to this issue by studying the multi-digit tactile perception as influenced by alterations in somatosensory maps. To address this specific aim, focal hand dystonia was chosen as a model of altered somatotopic maps. We used the Aristotle’s illusion to specifically investigate the functional meaning of the interplay between different fingers in tactile perception. Since, behavioural and neurophysiological studies indicate that the mechanisms underlying this illusion involve primary somatosensory cortex, and since a number of FHD neuroimaging studies have widely demonstrated anatomical alterations in the primary somatosensory cortex of FHD patients, we would expect that the Aristotle’s illusion is compromised in focal hand dystonia. This result would demonstrate a case of interdigit functional somatosensory alterations as specific counterpart of the widely reported anatomical alteration of somatosensory maps. However, FHD shares common somatosensory alterations features with other forms of focal dystonia and with PD. This is probably due to a common underlying factor: the abnormal basal ganglia activity. In order to exclude any possible role of basal ganglia in potentially modulation of Aristotle’s illusion in FHD we performed two experiments in which we compared the Aristotle’s illusion in FHD with other forms of focal dystonia and PD. Altogether, the two experiments: 1) confirm that fingers representation is specifically altered in FHD, and 2) demonstrate that abnormal alterations in fingers representation determine distorted tactile perception of objects simultaneously touched by different digits. The second study investigated the role the of body schema in processing thermotactile stimuli. More precisely, we studied how multiple thermotactile innocuous stimuli are combined in an unusual paradoxical painful sensation, termed Thermal Grill Illusion (TGI). In the classical TGI, innocuous warm and cold stimuli are arranged in a warm-cold-warm fashion. Intriguingly, this type of stimulation evokes a feeling of burning heat. In the second study, we applied the warm-cold-warm pattern on the first three digits (index, middle, and ring) and we observed whether the TGI was modulated by changing the relative spatial position of the fingers, that is by crossing or uncrossing the middle over the index. Using this simple method we found that the perceptual experience of paradoxical pain might arise from the integration of multiple thermal inputs based on the relative position of the stimulated fingers according to external frame of reference. Indeed, in the crossed position, the paradoxical heat sensation was reduced when the cooled finger was the middle, and increased when the cooled finger was the index. This interesting result indicates that the brain takes into account the relative spatial position of each stimulus to produce the paradoxical heat sensation termed TGI.
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19

Pohlmann, Gabriele [Verfasser]. "Therapie von Xenotransplantaten humaner gastrointestinaler Karzinome mit einer Kombination von intratumoraler Radioimmuntherapie (131 J-MAK BW 431/26) und systemischer Chemotherapie (Mitomycin C) / vorgelegt von Gabriele Pohlmann." 2000. http://d-nb.info/964566869/34.

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20

"Seelisch gesund von Anfang an : Programm und Abstracts des 26. Symposiums der Fachgruppe Klinische Psychologie und Psychotherapie der Deutschen Gesellschaft für Psychologie, 1. - 3. Mai 2008 in Potsdam." Universität Potsdam, 2008. http://opus.kobv.de/ubp/volltexte/2008/1755/.

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Abstract:
Der Tagungsband enthält das Programm und die Abstracts des 26. Symposiums der Fachgruppe Klinische Psychologie und Psychotherapie der Deutschen Gesellschaft für Psychologie, veranstaltet an der Universität Potsdam vom 1. bis 3. Mai 2008. Etwa 450 Kongressteilnehmer präsentieren den aktuellen Forschungs- und Wissensstand der Klinischen Psychologie und Psychotherapie in Deutschland. Grußworte halten die brandenburgische Ministerin für Arbeit, Soziales, Gesundheit und Familie, Dagmar Ziegler, die Präsidentin der Universität Potsdam, Prof. Dr.-Ing. Dr. Sabine Kunst, sowie Prof. Dr. Michael Linden als Vertreter der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN). Zu den Themenschwerpunkten des Kongresses gehören Einflussfaktoren auf die psychische Gesundheit Älterer, Impulsivität, Schlaf- und Traumforschung in der Klinischen Psychologie, Behandlung von Essstörungen, Wirksamkeitsstudien psychischer Störungen des Kindes- und Jugendalters, Angst und Depression, Behandlung von Kriegs- und Folteropfern, Risiko- und Schutzfaktoren der Kindesentwicklung sowie Adipositas im Kindes- und Jugendalter. Außer den Vorträgen gibt es eine Präsentation von etwa 150 Postern. Zum Programm der Tagung gehört ebenso die Verleihung des Klaus-Grawe-Awards for the Advancement of Innovative Research in Clinical Psychology and Psychotherapy an Prof. Dr. Timothy J. Strauman von der Duke University (USA), die Verleihung der Nachwuchswissenschaftler- und Posterpreise sowie ein Pre-conference Workshop für Doktorandinnen und Doktoranden der Klinischen Psychologie zum Thema "Verhaltens- und Molekulargenetik".
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