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1

Fomenko, Dmitri E., Anastazia Z. Metlitskaya, Jean Péduzzi, et al. "Microcin C51 Plasmid Genes: Possible Source of Horizontal Gene Transfer." Antimicrobial Agents and Chemotherapy 47, no. 9 (2003): 2868–74. http://dx.doi.org/10.1128/aac.47.9.2868-2874.2003.

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ABSTRACT Microcin C51 (MccC51) is an antimicrobial nucleotide-heptapeptide produced by a natural Escherichia coli strain. A 5.7-kb fragment of the pC51 plasmid carrying the genes involved in MccC51 production, secretion, and self-immunity was sequenced, and the genes were characterized. The sequence of the MccC51 gene cluster is highly similar to that of the MccC7 gene. Recombinant plasmids carrying different combinations of the mcc genes involved in the MccC51 production or immunity were constructed to characterize their functional roles. The mccA, mccB, mccD, and mccE genes are involved in M
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2

Liu, Qi, Weiping Hao, Yongguang Yang, et al. "Effects of Size and Dispersity of Microcrystalline Celluloses on Size, Structure and Stability of Nanocrystalline Celluloses Extracted by Acid Hydrolysis." Nano LIFE 04, no. 04 (2014): 1441014. http://dx.doi.org/10.1142/s1793984414410141.

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Nanocrystalline celluloses (NCCs) were separated from four commercial microcrystalline celluloses (MCCs) by an acid hydrolysis–sonication treatment. Transmission electron microscopy (TEM), atomic force microscopy (AFM), Fourier transform infrared (FTIR) spectrum, X-ray diffraction (XRD) and thermogravimetric analysis (TGA) were conducted to investigate the NCCs. MCCs with different morphologies and particle sizes showed different aggregation degrees. The aggregation of MCCs followed the order MCC1 > MCC3 > MCC2 > MCC4, which is the same order of the heights of the resulting NCCs. The
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3

Stamhuis, Eize J., Henk Maatman, and Geert E. H. Joosten. "Reactions of alicyclic ketones in carbon tetrachloride. II. Kinetics of the chlorination of 2-chlorocyclopentanone and 2-chlorocyclohexanone, catalyzed by hydrogen chloride." Canadian Journal of Chemistry 64, no. 9 (1986): 1690–96. http://dx.doi.org/10.1139/v86-278.

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The kinetics of the direct chlorination of 2-chlorocyclopentanone (2-mccp) and 2-chlorocyclohexanone (2-mcch) in carbon tetrachloride, catalyzed by hydrogen chloride, were studied. Reaction products are all the possible 2,2-, 2,5-, and 2,6-dichloro compounds. The ratios depend on the concentrations of the monochloro compound and hydrogen chloride. Surprisingly, even at conversions of the monochloro compound as low as 2%, 2,2,5-trichlorocyclopentanone and 2,2,6-trichlorocyclohexanone, respectively, are also formed. The chlorination reaction of both monochloro ketones shows zero order in chlorin
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4

Ananthapadmanabhan, Varsha, Yogesh Chutake, Jessica Filiatrault, Stefanie Schalm, Alice McDonald, and James A. DeCaprio. "Abstract C134: The MDM2 degrader KTX-049 is highly potent in TP53 wild-type (p53 WT) Merkel cell carcinoma (MCC)." Molecular Cancer Therapeutics 22, no. 12_Supplement (2023): C134. http://dx.doi.org/10.1158/1535-7163.targ-23-c134.

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Abstract Background and aims: MCC is a highly aggressive neuroendocrine carcinoma of the skin with a high fatality rate. Clonal integration of Merkel cell polyomavirus (MCPyV) occurs in about 80% of all MCCs. These virus positive MCC (MCCP) tumors have a low tumor mutational burden and usually express wild type (WT) p53 (TP53). In contrast, virus negative MCC (MCCN) tumors present a predominantly UV mutational signature, a high mutational burden and often have alterations in p53. MCCP tumors express MCyV small T antigen (ST) and a truncated form of large T antigen (LT). The MCyV ST in MCCP tum
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Semmate, Noha, Zahra Bamouh, Zouhair Elkarhat, et al. "The Development and Evaluation of a New Inactivated Vaccine against Mycoplasma capricolum subsp. capricolum." Microorganisms 12, no. 6 (2024): 1118. http://dx.doi.org/10.3390/microorganisms12061118.

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Mycoplasma capricolum subsp. capricolum (Mcc) and Mycoplasma capricolum subsp. capripneumoniae (Mccp) are pathogens that affect large and small ruminants. Indeed, Mcc affects both sheep and goats, causing contagious agalactia (CA). Mccp affects only goats, causing contagious caprine pleuropneumonia (CCPP). CA and CCPP are mainly controlled using inactivated Mcc and Mccp vaccines. However, producing the vaccine with the Mccp strain is complex, fastidious, and costly due to the slow growth of the bacterium. In this study, we present new oil-adjuvanted and inactivated Mcc and Mccp vaccines for sh
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6

Adhiambo, Onywera Ruth, Mungube Erick Ouma, Wesonga Hezron, Ngaira Jane, and Gicheru Nimmo. "Effect of glycerol on preservation of Mycoplasma capricolum subsp. capripneumonia (Mccp) in frozen lung Samples." Journal of Agriculture, Science and Technology 23, no. 2 (2024): 1–10. http://dx.doi.org/10.4314/jagst.v23i2.1.

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Mycoplasma capricolum subspecies capripneumoniae (Mccp) is the causative agent of contagious caprine pleuropneumonia (CCPP), a disease that affects the respiratory system of goats. Diagnosis of CCPP encounters challenges since Mccp is fastidious making it difficult to isolate or revive from stored samples. This study assessed the effect of glycerol on success of isolating Mccp from stored lung tissues. Experimentally infected goats developed fever and respiratory both consistent with CCPP and about 83% of the infected goats showed a variety of gross lesions including red hepatization, hyperemi
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7

Lilan, Ding, and Nurul Hanim Romainoor. "Structural Equation Modelling of the Influencing Mechanism of Museum Cultural and Creative Product Purchase Intention." Journal of Social Science and Humanities 6, no. 3 (2023): 22–32. http://dx.doi.org/10.26666/rmp.jssh.2023.3.4.

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The factors influencing the purchase intention (PI) towards Chinese museum cultural and creative products (MCCP) were investigated. A structural equation model that considered the specific MCCP characteristics was used. The transmission mechanism of consumers’ formation of MCCP PI was explored using antecedent variables (stimuli: perceived enjoyment [PE], perceived quality [PQ], perceived value [PV], and perceived culture [PC] and consumer-perceived normative factors: subjective norms [SN] and perceived behavioural control [PBC]); mediating variables (consumers’ cognitive and emotional states:
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8

Yang, Mo, Xin-Feng Wang, Jing-Wen Huang, et al. "Distribution, Sources, and Health Risk of Short-, Medium- and Long-Chain Chlorinated Paraffins in School-Area Ambient PM1: A Study from the Pearl River Delta, China." Toxics 13, no. 6 (2025): 467. https://doi.org/10.3390/toxics13060467.

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Background: Only a few studies have reported on chlorinated paraffin (CP) levels, especially long-chain chlorinated paraffins (LCCPs), in submicron particulate matter (PM1) in the outdoor air around primary and secondary schools. Methods: This study examined concentrations of short-chain CPs (SCCPs), medium-chain CPs (MCCPs), and LCCPs in PM1 samples from 96 schools across six cities in China’s Pearl River Delta region during the winter (October to December 2018). Results: The median total CP concentration was 34 ng/m3, with median values for SCCP, MCCP, and LCCP of 17.3, 15, and 0.7 ng/m3, re
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9

Li, He, Ye Zhu, Qihan Guo, Jingyu Wang, Mingxi Shi, and Weishang Liu. "Unveiling Consumer Satisfaction with AI-Generated Museum Cultural and Creative Products Design: Using Importance–Performance Analysis." Sustainability 16, no. 18 (2024): 8203. http://dx.doi.org/10.3390/su16188203.

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While artificial intelligence (AI) is being increasingly utilized in the design of museum cultural and creative products (MCCPs), limited research has explored consumer satisfaction with these AI-generated designs. This study quantitatively examined the impact of AI-generated MCCP design on consumer satisfaction and proposed strategies for improvement. A comprehensive evaluation system consisting of fourteen factor indicators across four dimensions was constructed through literature research, user interviews, and expert suggestions. On this basis, a survey with 297 consumers was then conducted
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10

Benigno, Nathilla dos Santos, Pedro Henrique Lustosa Soares, Isabella Rissi Vicentini de Morais, et al. "A importância do atendimento centrado na pessoa na adesão ao tratamento de transtorno de ansiedade." Brazilian Journal of Health Review 8, no. 1 (2025): e76751. https://doi.org/10.34119/bjhrv8n1-146.

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O trabalho explora a importância do Método Clínico Centrado na Pessoa (MCCP) na adesão ao tratamento do transtorno de ansiedade (TA), justificando-se pela alta prevalência desse transtorno no Brasil, que atinge 9,3% da população, e pela necessidade de abordagens que integrem fatores biopsicossociais no atendimento. O objetivo central é investigar como o MCCP pode influenciar positivamente a adesão dos pacientes ao tratamento, promovendo uma relação médico-paciente mais humanizada e colaborativa. Com base em uma revisão bibliográfica, destacam-se evidências de que o MCCP, ao favorecer a criação
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11

Du, Fangzhou, Lin Zhou, Yan Jiao та ін. "Ingredients in Zijuan Pu’er Tea Extract Alleviate β-Amyloid Peptide Toxicity in a Caenorhabditis elegans Model of Alzheimer’s Disease Likely through DAF-16". Molecules 24, № 4 (2019): 729. http://dx.doi.org/10.3390/molecules24040729.

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Amyloid-β, one of the hallmarks of Alzheimer’s disease (AD), is toxic to neurons and can also cause brain cell death. Oxidative stress is known to play an important role in AD, and there is strong evidence that oxidative stress is associated with amyloid-β. In the present study we report the protective effect of Zijuan Pu’er tea water extract (ZTWE) and the mixture of main ingredients (+)-catechins, caffeine and procyanidin (MCCP) in ZTWE on β-amyloid-induced toxicity in transgenic Caenorhabditis elegans (C. elegans) CL4176 expressing the human Aβ1–42 gene. ZTWE, (+)-catechins, caffeine, procy
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12

Rehman, Faiz Ur, Farhan Anwar Khan, Muhammad Saeed, et al. "Clinicopathological and Sero-Molecular Detection of Mycoplasma capricolum subsp. capripneumoniae in Goats in Southern Areas of Pakistan." Veterinary Medicine International 2022 (October 3, 2022): 1–11. http://dx.doi.org/10.1155/2022/9508810.

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Contagious caprine pleuropneumonia (CCPP) is a highly fatal infectious disease of goats, caused by Mycoplasma capricolum subsp. capripneumoniae (Mccp). This disease is causing huge economic losses to the goat industry in Pakistan. However, little is known about the epidemiology of CCPP, especially in the hard areas of Khyber Pakhtunkhwa (KP), Pakistan, despite having a huge population of goats. Therefore, this study aimed to elucidate sero-molecular epidemiology and pathology associated with Mccp infection in goats in southern areas of KP including Dera Ismail Khan (DI Khan), Bannu, Karak, and
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13

Wenceslau, Leandro David, Eberhart Portocarrero-Gross, and Marcelo Marcos Piva Demarzo. "Compaixão e medicina centrada na pessoa: convergências entre o Dalai Lama Tenzin Gyatso e Ian McWhinney." Revista Brasileira de Medicina de Família e Comunidade 11, no. 38 (2016): 1–10. http://dx.doi.org/10.5712/rbmfc11(38)1138.

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O método clínico centrado na pessoa (MCCP) é uma proposta de reorientação da prática clínica que identifica um distanciamento, na medicina contemporânea, da experiência subjetiva e qualitativa dos pacientes. Para superar este distanciamento, o MCCP utiliza teorias e técnicas de diversas escolas da psicologia moderna ocidental. Neste trabalho, analisamos possíveis contribuições para o MCCP de uma escola de pensamento oriental, o budismo tibetano, na perspectiva delineada por seu atual líder espiritual, Tenzin Gyatso, o XIV Dalai Lama. Também são utilizados elementos de trabalhos de Ian McWhinne
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14

Han, Daocai, Siow-Kian Tan, and Booi-Chen Tan. "Culture, art, technology, and perception: A creative generation model for museum cultural and creative product design." International Journal of Innovative Research and Scientific Studies 8, no. 3 (2025): 1346–61. https://doi.org/10.53894/ijirss.v8i3.6800.

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This study is dedicated to an in-depth exploration of the key elements and internal mechanisms of the creative generation of museum cultural and creative products (MCCPs). Given the fragmented state of previous studies and the lack of a unified framework, this study aims to gain a deeper understanding of the creative process of MCCP design. An exploratory qualitative research method was chosen, with grounded theory as the basic method. From January to May 2024, data was collected from multiple sources. These included interviews with designers, craftsmen, museum staff, and consumers, as well as
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15

Shahait, Mohammed, Mohammed Alshalalfa, Edward M. Schaeffer, et al. "Head-to-head comparison between decipher and prolaris tests: Two commercially available post-prostatectomy genomic tests." Journal of Clinical Oncology 38, no. 6_suppl (2020): 348. http://dx.doi.org/10.1200/jco.2020.38.6_suppl.348.

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348 Background: Several post-prostatectomy genomic tests are available; which are used to improve prognostication and to guide additional treatment after radical prostatectomy (RP). There has been no head to head comparison between these tests. The objective of this study is to compare the performance of two genomic tests in predicting oncological outcomes. Methods: 16 patients who underwent RP at the University of Pennsylvania (UPenn) (2013-2018), had adverse pathology (margin, and/or pT3a/b) and had each been tested with both Decipher (D) and Prolaris (P). Pearson correlation was used to com
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16

De Alcântara, Cássio Mendes, and Mak Alisson Borges De Moraes. "As contribuições do método clínico centrado na pessoa em publicações brasileiras: uma revisão de literatura." OBSERVATÓRIO DE LA ECONOMÍA LATINOAMERICANA 21, no. 8 (2023): 9941–64. http://dx.doi.org/10.55905/oelv21n8-113.

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Este paper objetiva-se em investigar as contribuições do Método Clínico Centrado na Pessoa (MCCP) a partir de publicações em periódicos brasileiros na última década [2012-2022]. Para tanto, desenvolveu-se um trabalho de Revisão de Literatura, de natureza Sistemática, junto a base da dados do Google Scholar. Utilizou-se os seguintes blocos de descritores, como estratégia de busca, para o levantamento das produções científicas: “Método” OR “Clínico” OR “Centrado na Pessoa”; “Cuidado” OR “Clínico” OR “Centrado na pessoa”; “Método” OR “Clínico” OR “Centrado no Paciente”. Ao total, encontrou-se 446
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17

Jarboe, D. L., and T. F. Huff. "The mast cell-committed progenitor. II. W/Wv mice do not make mast cell-committed progenitors and S1/S1d fibroblasts do not support development of normal mast cell-committed progenitors." Journal of Immunology 142, no. 7 (1989): 2418–23. http://dx.doi.org/10.4049/jimmunol.142.7.2418.

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Abstract We have previously reported that the population of mesenteric lymph node cells from normal BALB/c mice infected 14 days with the rodent nematode Nippostrongylus brasiliensis (Nb-MLN) contains a nongranulated mast cell-committed progenitor (MCCP) which does not require IL-3 for proliferation and differentiation if either a fibroblast monolayer or soluble factors produced by monolayers of 3T3 fibroblasts or embryonic skin are present in the culture. When Nb-MLN were cloned in a methylcellulose culture system using fibroblast conditioned medium as the only source of growth factors, numer
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18

Baziki, Jean de Dieu, Bodjo S. Charles, Nick Nwankpa, et al. "Development and Evaluation of an Immuno-Capture Enzyme-Linked Immunosorbent Assay to Quantify the Mycoplasma capricolum subsp. capripneumoniae (Mccp) Protein in Contagious Caprine Pleuropneumonia (CCPP) Vaccine." Veterinary Medicine International 2020 (January 29, 2020): 1–10. http://dx.doi.org/10.1155/2020/4236807.

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An effective contagious caprine pleuropneumonia (CCPP) vaccine is essential for the increased production of healthy goats in a cost-effective manner and the prevention of animal-to-animal transmission for both domestic animals and wildlife. Quality control of this vaccine ensures that a reliable supply of pure, safe, and potent batches is obtained. As part of this control, in vitro quantification of Mycoplasma capricolum subsp. capripneumoniae (Mccp) protein in the final vaccines is required before the CCPP vaccine undergoes batch release and certification. The current method used for quantifi
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19

Yousafzai, Haider Ali, Shahid Hussain Abro, Abdul Sajid, et al. "Insights into Clinical Features and Antibiotic Response in MCCP Infection among Small Ruminants." Journal of Agriculture and Veterinary Science 3, no. 2 (2024): 209–15. https://doi.org/10.55627/agrivet.003.02.0635.

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This study documents the clinical manifestations observed during sample collection from diseased small ruminants. The samples and clinical data were collected from CCPP suspected sheep and goat flocks. The culturing of Mycoplasma was performed using Modified Hay Flick medium. Mccp species were identified by biochemical profile. Antibiogram of the isolated strains was performed according to CLSI using various antibiotics including ampicillin, ceftiofur sodium, gentamicin, cloxacillin, tylosin, metronidazole, oxytetracycline, enrofloxacin and ciprofloxacin. Among the 385 culture-positive samples
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20

Machado, Carolina, Isabela de Souza Simões, Giovanna André Cardoso, Guilherme Ribeiro, Izadora Motta, and Roque Eduardo Mello. "Do indivíduo ao social: ampliando o método clínico centrado na pessoa – um relato de experiência." Brazilian Journal of Health Review 8, no. 2 (2025): e78225. https://doi.org/10.34119/bjhrv8n2-050.

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O livro: “Do Indivíduo ao social: Ampliando o Método Clínico Centrado na Pessoa” foi criado como uma ferramenta pedagógica durante a pandemia de COVID-19, como uma forma de superar a barreira sanitária. Baseado no Método clínico Centrado na Pessoa (MCCP), o projeto visou capacitar estudantes da Universidade do Vale do Itajaí a compreenderem a complexidade do cuidado integral, buscando ultrapassar os limites impostos pelo método clínico tradicional. Para tanto, a obra apresenta casos reais narrados por preceptores e residentes, que comparam o MCCP ao modelo biomédico. Cada caso é acompanhado de
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21

Metges, J., E. Gamelin, R. Faroux, et al. "AVASTERB OUEST: A prospective cohort study of unresectable metastatic colon cancer treated successively by FOLFIRI bevacizumab and cetuximab irinotecan." Journal of Clinical Oncology 27, no. 15_suppl (2009): e15103-e15103. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e15103.

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e15103 Background: Bevacizumab and cetuximab regimen are approuved since 2005 in Europe for Metastatic Colorectal Cancer Patients (MCCP). Very few studies have reported data concerning the sequence (FOLFIRI BEVA and after failure CETUXIMAB- CAMPTO) in MCCP from the real world. Methods: Since 2003, in west of France, (Bretagne-Pays de Loire),a network called OMIT(Observatoire des Médicaments et Innovations Thérapeutiques) directed by Regional Health Agencies has been created. This structure gathered prospectively data from MCCP treated with targeted therapies. Since 2006, a cohort of MCCP treat
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22

Mao, Jianming, Jianwei Wang, Guping Tang, Paul K. Chu, and Hongzhen Bai. "A zipped-up tunable metal coordinated cationic polymer for nanomedicine." Journal of Materials Chemistry B 8, no. 7 (2020): 1350–58. http://dx.doi.org/10.1039/c9tb02965f.

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23

Wenceslau, Leandro David, Victor Kelles Tupy da Fonseca, Luíza de Alcântara Dutra, and Letícia Gonçalves Caldeira. "Um roteiro de entrevista clínica centrada na pessoa para a graduação médica." Revista Brasileira de Medicina de Família e Comunidade 15, no. 42 (2020): 2154. http://dx.doi.org/10.5712/rbmfc15(42)2154.

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O ensino de habilidades de comunicação clínica na graduação médica encontra nos princípios e componentes do Método Clínico Centrado na Pessoa (MCCP) uma referência importante para a definição de suas competências. No entanto, mesmo tendo contato com o MCCP em sua formação, é frequente que estudantes de medicina recorram à utilização da anamnese tradicional centrada na agenda médica como um roteiro mais seguro para realização de suas entrevistas. Propomos, como uma hipótese para essa dificuldade dos estudantes, a falta de uma tradução do MCCP em um roteiro padronizado de entrevista médica, espe
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24

Samiullah, S. "Contagious caprine pleuropneumonia and its current picture in Pakistan: a review." Veterinární Medicína 58, No. 8 (2013): 389–98. http://dx.doi.org/10.17221/6977-vetmed.

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Contagious caprine pleuropneumonia (CCPP) is caused by Mycoplasma capricolum subsp. capripneumoniae (Mccp) which belongs to the Mycoplasma mycoides cluster, a group of five closely related Mycoplasmas, pathogenic to ruminants. The true lesions of CCPP are restricted to the alveolar tissues of infected goats, which distinguish it from other respiratory diseases of small ruminants caused by members of the Mycoplasma mycoides cluster. The typical signs of CCPP are an accumulation of pleural fluid, unilateral hepatisation, adhesions, pleurisy and pleuropneumonia which clearly differentiate it from
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Castro, Rodrigo Caprio Leite de, and Daniela Riva Knauth. "Associação entre a abordagem médica centrada na pessoa e a satisfação com a consulta em atenção primária à saúde." Revista Brasileira de Medicina de Família e Comunidade 16, no. 43 (2021): 2702. http://dx.doi.org/10.5712/rbmfc16(43)2702.

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Introdução: A aplicação do método clínico centrado na pessoa (MCCP) busca alcançar a compreensão da pessoa e da sua doença por meio da abordagem de duas perspectivas: a do médico e a da pessoa. A satisfação dos usuários é considerada um importante indicador de avaliação dos serviços. Objetivo: O presente artigo tem como objetivo investigar se há associação entre o grau de orientação ao MCCP, segundo a percepção da pessoa, e a satisfação com a última consulta médica em um serviço de atenção primária à saúde (APS). Metodologia: Trata-se de estudo transversal, realizado com pessoas com hipertensã
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Eller, Jakob, Sascha Hein, and Jörg Simon. "Significance of MccR, MccC, MccD, MccL and 8-methylmenaquinone in sulfite respiration of Wolinella succinogenes." Biochimica et Biophysica Acta (BBA) - Bioenergetics 1860, no. 1 (2019): 12–21. http://dx.doi.org/10.1016/j.bbabio.2018.10.002.

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27

Wu, Xinyu, Zhongyang Bai, Lin Wang, et al. "Magnetic Cell Centrifuge Platform Performance Study with Different Microsieve Pore Geometries." Sensors 20, no. 1 (2019): 48. http://dx.doi.org/10.3390/s20010048.

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The detection and analysis of circulating tumor cells (CTCs) plays a crucial role in clinical practice. However, the heterogeneity and rarity of CTCs make their capture and separation from peripheral blood very difficult while maintaining their structural integrity and viability. We previously demonstrated the effectiveness of the Magnetic Cell Centrifuge Platform (MCCP), which combined the magnetic-labeling cell separation mechanism with the size-based method. In this paper, a comparison of the effectiveness of different microsieve pore geometries toward MCCP is demonstrated to improve the yi
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McGrath, Thomas J., Giulia Poma, Hidenori Matsukami, Govindan Malarvannan, Natsuko Kajiwara, and Adrian Covaci. "Short- and Medium-Chain Chlorinated Paraffins in Polyvinylchloride and Rubber Consumer Products and Toys Purchased on the Belgian Market." International Journal of Environmental Research and Public Health 18, no. 3 (2021): 1069. http://dx.doi.org/10.3390/ijerph18031069.

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This study investigates the presence of Stockholm Convention listed short-chain chlorinated paraffins (SCCPs) and their replacement medium-chain chlorinated paraffins (MCCPs) counterparts in polyvinyl chloride and rubber consumer products and toys purchased on the Belgian market in 2019. SCCPs were detected in 27/28 samples at concentrations ranging from <LOQ–130,000 µg/g with a median level of 2.5 µg/g, while MCCPs were detected in only five samples ranging <LOQ–3500 µg/g. Levels of SCCPs in all but one of the samples were below the European Union’s guideline limit of 0.15%, by weight,
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Jarboe, D. L., J. S. Marshall, T. R. Randolph, A. Kukolja, and T. F. Huff. "The mast cell-committed progenitor. I. Description of a cell capable of IL-3-independent proliferation and differentiation without contact with fibroblasts." Journal of Immunology 142, no. 7 (1989): 2405–17. http://dx.doi.org/10.4049/jimmunol.142.7.2405.

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Abstract We have identified a late, committed stage in the differentiation of the mast cell progenitor just before granulation. Mast cell committed progenitors (MCCP) are nongranulated cells with a density of 1.060 to 1.070 g/ml which can be harvested from the mesenteric lymph node of mice infected with Nippostrongylus brasiliensis. Mast cell-committed progenitors are able to proliferate and differentiate in the absence of IL-3 or IL-4 when cultured on a monolayer of embryonic skin or 3T3 fibroblasts and can form colonies in methylcellulose supplemented with fibroblast conditioned medium. Fibr
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Abd. Rahim, Siti Fadhilah, Normala Masrom, Muhamad Cyrill Kamal, Khairul Basyar Baharudin, Norliza Abu Bakar, and Noor Azmi Shaharuddin. "Assessment of Selected Herbicides and Chelating Agents in Water Using Gas Chromatography-Electron Capture Detector (GC-ECD)." Bioremediation Science and Technology Research 3, no. 1 (2015): 26–30. http://dx.doi.org/10.54987/bstr.v3i1.250.

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Water contamination by herbicides and chelating agents is increasing mainly due to the increasing agricultural activities. Water contamination by these compounds has become a concern due to their adverse effects to the environment and humans. Seven sampling sites of water sources in Selangor and Johor were chosen for the study. Contamination level of Mecoprop (MCCP), Nitrilotriacetic acid (NTA) and Ethylenediaminetetraacetic acid (EDTA) in these water body areas was determined by using Gas Chromatography-Electron Capture Detector (GC-ECD). Our results indicated that water samples of Sung
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Yousafzai, Haider Ali, Shahid Hussain Abro, Abdul Sajid, et al. "IMPROVING MCCP VACCINE IN SHEEP: NOVEL STRATEGIES FOR DEVELOPMENT, EFFICACY AND CROSS-PROTECTION." Pakistan Journal of Biotechnology 21, no. 2 (2024): 272–78. http://dx.doi.org/10.34016/pjbt.2024.21.02.919.

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Vaccination serves as a straightforward and efficient method for preventing numerous infectious diseases in animals. One such disease is contagious caprine pleuropneumonia (CCPP), a severe lung ailment affecting small ruminants. This research aimed to create a vaccine utilizing Mycoplasma capricolum subsp. capripneumoniae (Mccp) isolated from KPK, Pakistan. The local Mccp strain was rendered inactive alongside saponin, a substance, to produce the vaccine. The viable count of Mycoplasma mycoides subsp. capripneumoniae (Mccp) was determined to be 1x108 CFU/mL from the stock culture, with an esti
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Li, Xiaoying, Haiqiang Guo, Jianyao Hong, Yuan Gao, Xindong Ma, and Jiping Chen. "Short- and Medium-Chain Chlorinated Paraffins in the Sediment of the East China Sea and Yellow Sea: Distribution, Composition, and Ecological Risks." Toxics 11, no. 7 (2023): 558. http://dx.doi.org/10.3390/toxics11070558.

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Chlorinated paraffins (CPs), a class of complex mixtures synthesized from polychlorinated n-alkanes, are widely used as flame retardants, plasticizers, lubricant additives, coolants, metalworking cutting fluids, and sealants. This study investigated the spatial distribution, the potential pollution sources, and ecological risk of 24 short-chain CPs (SCCPs) and 24 medium-chain CPs (MCCPs) from 29 surface marine sediment samples from the East China Sea and Yellow Sea in September 2019. All of the 48 CPs were detected. The concentrations of SCCPs and MCCPs ranged from 0.703 to 13.4 ng/g dw and 0.
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Oliveira, Daniele Calaça de, and Maria Olívia Lima de Mendonça. "Autoconhecimento e autocura na perspectiva da ginecologia natural." Revista Brasileira de Medicina de Família e Comunidade 18, no. 45 (2023): 3853. http://dx.doi.org/10.5712/rbmfc18(45)3853.

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A Ginecologia Natural, conhecida por ser uma ginecologia autônoma e política, é compreendida como um movimento político e pedagógico que questiona a aliança médico-farmacêutica e resgata saberes ancestrais, reivindicando o autoconhecimento como forma de empoderamento pessoal. Ela antepõe-se aos processos de patologização, medicalização e comercialização que são especialmente voltados para os corpos feminizados e propõe um olhar sistêmico sobre os processos de saúde-doença, levando em consideração as dimensões corporais, mentais e energéticas (espirituais) do ser. Diante disso, são percebidas i
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Cuba-Fuentes, Maria, Janet Angelina Contreras Samamé, Paúl Steve Ravello Ríos, Miriam Aydeé Castillo Narro, and Saúl Alan Coayla Flores. "La medicina centrada en el paciente como método clínico." Revista Medica Herediana 27, no. 1 (2016): 60. http://dx.doi.org/10.20453/rmh.v27i1.2786.

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El modelo biomédico tradicional centrado en la enfermedad, con su énfasis en la tecnología, en los últimos años viene siendo cuestionado; en su lugar, se propugna el Modelo biopsicosocial, más integral, sistémico y holístico, que se centra en la persona como un ser biológico, psicológico y social. Para responder adecuadamente las necesidades y expectativas de los pacientes surge el método clínico centrado en el paciente (MCCP) desarrollado por Stewart y Brown (1995). Para ejemplificarlo, en este artículo tomamos un caso clínico, desarrollando los cuatro componentes de la MCCP: la exploración d
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Ramírez López, Berenice. "El Grupo de los Ocho: ¿Comunidad de intereses o intereses en búsqueda de una concertación?" Estudios Latinoamericanos 3, no. 4 (1988): 73. http://dx.doi.org/10.22201/cela.24484946e.1988.4.47149.

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Los días 27, 28 y 29 de noviembre del año pasado,se reunieron en Acapulco, México, los ocho presidentes latinoamericanos que en representación de sus países forman parte del Mecanismo Permanente de Consulta y Concertación Política (MCCP).
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Dias dos Santos, Aarão Carajás, Isabel Brandão Correia, and Rubens Cavalcanti Silva. "O Tao na Medicina de Família e Comunidade: Relações entre Acupuntura e o Método Clínico Centrado na Pessoa." Revista Brasileira de Medicina de Família e Comunidade 14, no. 41 (2019): 1624. http://dx.doi.org/10.5712/rbmfc14(41)1624.

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Objetivo: Compreender a extensão dos componentes do Método Clínico Centrado na Pessoa na prática da acupuntura a partir da percepção dos usuários. Métodos: Por meio de uma pesquisa qualitativa com grupo focal, buscou-se entender como a acupuntura faz a pessoa perceber suas experiências de saúde e doença; intensifica a percepção da pessoa enquanto ser integral; viabiliza a pessoa se sentir participante do processo de cuidado; auxilia na intensificação da relação médico-pessoa. Resultados: Emergiram temas que versavam sobre emancipação, autoconhecimento, integralidade, vínculos e afetos, que for
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Nasr Esfahani, Maryam, Miyako Kusano, Kien Huu Nguyen, et al. "Adaptation of the symbiotic Mesorhizobium–chickpea relationship to phosphate deficiency relies on reprogramming of whole-plant metabolism." Proceedings of the National Academy of Sciences 113, no. 32 (2016): E4610—E4619. http://dx.doi.org/10.1073/pnas.1609440113.

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Low inorganic phosphate (Pi) availability is a major constraint for efficient nitrogen fixation in legumes, including chickpea. To elucidate the mechanisms involved in nodule acclimation to low Pi availability, two Mesorhizobium–chickpea associations exhibiting differential symbiotic performances, Mesorhizobium ciceri CP-31 (McCP-31)–chickpea and Mesorhizobium mediterranum SWRI9 (MmSWRI9)–chickpea, were comprehensively studied under both control and low Pi conditions. MmSWRI9–chickpea showed a lower symbiotic efficiency under low Pi availability than McCP-31–chickpea as evidenced by reduced gr
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Jean de Dieu, Baziki, Bodjo S. Charles, Nick Nwankpa, et al. "Development and Evaluation of Epitope-Blocking ELISA for Detection of Antibodies against Contagious Caprine Pleuropneumonia in Goat Sera." Veterinary Sciences 6, no. 4 (2019): 82. http://dx.doi.org/10.3390/vetsci6040082.

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Enzyme linked immunosorbent assays (ELISAs) have been developed for the detection of antibodies against contagious caprine pleuropneumonia (CCPP), the causative agent of which is Mycoplasma capricolum subsp. Capripneumoniae (Mccp). The currently available commercial CCPP competitive ELISA (CCPP cELISA) kit produced and supplied by IDEXX Company (Westbrook, Maine, United States) is relatively expensive for most African laboratories. To address this issue and provide a variety of choices, a sensitive and specific blocking-ELISA (b-ELISA) test to detect antibodies against CCPP was developed. We d
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Arnold, Roberta. "Witness Protection under Swiss Legislation: An Offspring of International Law." International Criminal Law Review 7, no. 2-3 (2007): 483–503. http://dx.doi.org/10.1163/156753607x204284.

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AbstractIn 2003 Switzerland adopted the first witness protection provisions in the Swiss Military Criminal Code of Procedure (MCCP). These followed to the lessons learned in the Niyonteze Trial, the first trial held in Switzerland on genocide. The military investigating magistrates had to be inventive and very pragmatic in providing for the security of the witnesses. Trips were even undertaken to the ICTR to learn about its practice and measures were adopted to prevent a "cultural shock". Notwithstanding the tendency of some human rights advocates to be very critical of military tribunals, in
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Valle, Isadora Machado, Isabelle Faoro Glaser, Jessica Heloise Camargo de Lima, Camila Ament Giuliani dos Santos Franco, Renato Soleiman Franco, and André Bisetto. "Adaptação cultural e validação da versão brasileira do questionário autopercepção do desempenho da medicina centrada na pessoa em medicina geral e familiar." Revista Brasileira de Medicina de Família e Comunidade 18, no. 45 (2023): 3881. http://dx.doi.org/10.5712/rbmfc18(45)3881.

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Introdução: O método clínico centrado na pessoa (MCCP) tem como objetivo proporcionar um atendimento humanizado e centrado no paciente. A aplicação do MCCP melhora a relação médico-paciente e tem impacto no desfecho clínico. No entanto, há desafios e realizar uma consulta centrada no paciente pode ter barreiras relacionadas com fatores que vão desde a aplicação da técnica até limitações por conta do contexto clínico. Diante da relevância do MCCP na prática clínica e do crescente estímulo para o ensino desse método, torna-se indispensável medir a autoavaliação dos médicos com relação à prática
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Abdulah, Amri, Budi Kristiawan, Wibawa Endra Juwana, Sukarman Sukarman, and Khoirudin Khoirudin. "Enhancement of Heat Transfer on a Mini Channel Cold Plate by Utilizing Nanofluids Across Various Reynolds Number Variants." Journal of Advanced Research in Fluid Mechanics and Thermal Sciences 128, no. 1 (2025): 108–22. https://doi.org/10.37934/arfmts.128.1.108122.

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This study aims to analyze the thermohydraulic performance of an aluminum mini-channel cold plate (MCCP) using Al₂O₃+EG/W nanofluids at various Reynolds numbers. The investigation focuses on the impact of Reynolds numbers, ranging from 953 to 1588 in laminar flow, on heat transfer enhancement and surface temperature reduction. The results clearly correlate higher Reynolds numbers and lower surface temperatures. The greatest wall temperature reduction of 12.53% was achieved using nanofluid at a Reynolds number of 1588. Heat transfer rates also increased with Reynolds numbers, from 45.93 W at Re
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Ahmed, Mona M., Camille H. Cushman, and James A. DeCaprio. "Merkel Cell Polyomavirus: Oncogenesis in a Stable Genome." Viruses 14, no. 1 (2021): 58. http://dx.doi.org/10.3390/v14010058.

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Merkel cell polyomavirus (MCV) is the causative agent for the majority of Merkel cell carcinoma (MCC) cases. Polyomavirus-associated MCC (MCCP) is characterized by the integration of MCV DNA into the tumor genome and a low tumor mutational burden. In contrast, nonviral MCC (MCCN) is characterized by a high tumor mutational burden induced by UV damage. Since the discovery of MCV, much work in the field has focused on understanding the molecular mechanisms of oncogenesis driven by the MCV tumor (T) antigens. Here, we review our current understanding of how the activities of large T (LT) and smal
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Castro, Rodrigo Caprio Leite de, and Daniela Riva Knauth. "Papel dos atributos dos profissionais médicos na produção da abordagem centrada na pessoa em atenção primária à saúde." Ciência & Saúde Coletiva 27, no. 2 (2022): 803–12. http://dx.doi.org/10.1590/1413-81232022272.00392021.

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Resumo Embora inúmeros fatores influenciem a abordagem médica, poucas pesquisas exploram a associação de características presentes no nível do médico com o tipo de prática por ele desempenhada. Este estudo tem como objetivo determinar os fatores que, no nível do médico, associam-se ao alto grau de orientação ao método clínico centrado na pessoa (MCCP), atribuído, pelas pessoas atendidas, à abordagem desse profissional em atenção primária à saúde (APS). O delineamento é transversal, realizado com pacientes hipertensos e/ou diabéticos e médicos em 12 unidades de um serviço de APS em Porto Alegre
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Fahim, C., J. Ratcliffe, M. McConnell, R. Sonnadara, and M. Simunovic. "Evaluating the reliability of a tool to measure the quality of gastrointestinal multidisciplinary cancer conferences: A generalizability study." Journal of Patient Safety and Risk Management 24, no. 2 (2018): 57–63. http://dx.doi.org/10.1177/2516043518816264.

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Background Lamb et al. developed the metric for the observation of decision-making tool (MTB-MODe) to evaluate the quality of urologic multidisciplinary cancer conferences (MCCs) in the United Kingdom. We used generalizability theory to assess the reliability of a modified version of MTB-MODe in a North American context. Specifically, we wished to determine if the tool could distinguish between high- and low-quality MCC decision-making. Methods Two assessors independently evaluated two MCCs (MCC1, MCC2) using the modified MTB-MODe. Generalizability theory was used to assess overall tool reliab
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Sprengel, Jannik, Peter A. Behnisch, Harrie Besselink, Abraham Brouwer та Walter Vetter. "In vitro human cell-based TTR-TRβ CALUX assay indicates thyroid hormone transport disruption of short-chain, medium-chain, and long-chain chlorinated paraffins". Archives of Toxicology 95, № 4 (2021): 1391–96. http://dx.doi.org/10.1007/s00204-021-02994-5.

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AbstractOver the last decades, short-chain chlorinated paraffins (SCCPs), medium-chain chlorinated paraffins (MCCPs), and long-chain chlorinated paraffins (LCCPs) have become the most heavily produced monomeric organohalogen compound class of environmental concern. However, knowledge about their toxicology is still scarce, although SCCPs were shown to have effects on the thyroid hormone system. The lack of data in the case of MCCPs and LCCPs and the structural similarity with perfluoroalkyl substances (PFAS) prompted us to test CPs in the novel TTR-TR CALUX assay for their thyroid hormone tran
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Dubey, Juhi, Anurag Verma, and Navneet Verma. "Evaluation of Chitosan Based Polymeric Matrices for Sustained Stomach Specific Delivery of Propranolol Hydrochloride." Indian Journal of Materials Science 2015 (August 27, 2015): 1–9. http://dx.doi.org/10.1155/2015/312934.

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The objective of the present investigation was to explore the potential of Chitosan based polymeric matrices as carrier for sustained stomach specific delivery of model drug Propranolol Hydrochloride. Briefly, single unit hydrodynamically balanced (HBS) capsule formulations were prepared by encapsulating in hard gelatin capsules, intimately mixed physical mixtures of drug, and cationic low molecular weight Chitosan (LMCH) in combination with either anionic medium viscosity sodium alginate (MSA) or sodium carboxymethylcellulose (CMCNa). The effect of incorporation of nonionic polymers, namely,
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Zellmer, Sebastian, Lisa Heiserich, Oliver Kappenstein, Stefan Merkel, Agnes Schulte, and Andreas Luch. "MCCP: are medium-chain chlorinated paraffins of concern for humans?" Archives of Toxicology 94, no. 3 (2020): 955–57. http://dx.doi.org/10.1007/s00204-020-02681-x.

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Dias, Eduardo Herrera, Elisangela Thaísa Gottardo, Taniara Suelen Mezalira, et al. "Use of a Multi-Carbohydrase Complex with Phytase in Diets of Broiler Chickens containing Ingredients of Animal Origin." Ensaios e Ciência C Biológicas Agrárias e da Saúde 27, no. 2 (2023): 146–54. http://dx.doi.org/10.17921/1415-6938.2023v27n2p146-154.

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Currently, the use of exogenous enzymes in the diet of broilers has grown, not only in diets based on corn and soybean meal, but also in diets with proteins of animal origin. The objective of this study was to evaluate the effect of supplementing a multi-carbohydrase complex (xylanase, glucanase, other carbohydrases) with phytase (MCCP) in broiler diets containing animal ingredients on performance, litter quality, jejunum morphometry and feed cost. Three treatments were evaluated: T1 - positive control diet: reference diet; T2 - negative control diet + MCCP; T3 - negative control diet (referen
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Rodrigo, Carvalho Almada Melo, and Lopes de Lima Reigada Carolina. ""DIZENDO NÃO" ÀS DEMANDAS POSSIVELMENTE IATROGÊNICAS DOS PACIENTES: UMA REVISÃO NARRATIVA." Revistaft 28, no. 132 (2024): 12. https://doi.org/10.5281/zenodo.10827912.

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Introdução: Cada vez há uma maior necessidade de os profissionais de saúde desenvolverem habilidades de comunicação para lidar com as demandas possivelmente iatrogênicas dos pacientes. Essas demandas incluem solicitações de exames, encaminhamentos e prescrições médicas desnecessárias, e que podem resultar em efeitos adversos para os pacientes caso não tenham uma indicação clara. Objetivo: Realizar uma revisão narrativa de literatura sobre ferramentas e habilidades em comunica&c
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Yatoo, Mohd, Oveas Parray, Muheet, et al. "Novel Candidates for Vaccine Development Against Mycoplasma Capricolum Subspecies Capripneumoniae (Mccp)—Current Knowledge and Future Prospects." Vaccines 7, no. 3 (2019): 71. http://dx.doi.org/10.3390/vaccines7030071.

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Exploration of novel candidates for vaccine development against Mycoplasma capricolum subspecies capripneumoniae (Mccp), the causative agent of contagious caprine pleuropneumonia (CCPP), has recently gained immense importance due to both the increased number of outbreaks and the alarming risk of transboundary spread of disease. Treatment by antibiotics as the only therapeutic strategy is not a viable option due to pathogen persistence, economic issues, and concerns of antibiotic resistance. Therefore, prophylactics or vaccines are becoming important under the current scenario. For quite some t
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