Relevant bibliographies by topics / MCD

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  2. Dissertations / Theses
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  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'MCD'

Author: Grafiati
Published: 4 June 2021
Last updated: 28 January 2023

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Journal articles on the topic "MCD"

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Jorgačević, B., D. Mladenović, M. Ninković, V. Prokić, MN Stanković, V. Aleksić, I. Cerović, et al. "Dynamics of oxidative/nitrosative stress in mice with methionine–choline-deficient diet-induced nonalcoholic fatty liver disease." Human & Experimental Toxicology 33, no. 7 (October 15, 2013): 701–9. http://dx.doi.org/10.1177/0960327113506723.

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Insulin resistance, oxidative stress, and proinflammatory cytokines play a key role in pathogenesis of nonalcoholic fatty liver disease (NAFLD). The aim of our study was to investigate the dynamics of oxidative/nitrosative stress in methionine–choline-deficient (MCD) diet -induced NAFLD in mice. Male C57BL/6 mice were divided into following groups: group 1: control group on standard diet; group 2: MCD diet for 2, 4, and 6 weeks (MCD2, MCD4, and MCD6, respectively). After treatment, liver and blood samples were taken for histopathology, alanine- and aspartate aminotransferase, acute phase reactants, and oxidative/nitrosative stress parameters. Liver malondialdehyde level was higher in all MCD-fed groups versus control group ( p < 0.01), while nitrites + nitrates level showed a progressive increase. The activity of total superoxide dismutase and its isoenzymes was significantly lower in all MCD-fed groups ( p < 0.01). Although catalase activity was significantly lower in MCD-fed animals at all intervals ( p < 0.01), the lowest activity of this enzyme was evident in MCD4 group. Liver content of glutathione was lower in MCD4 ( p < 0.05) and MCD6 group ( p < 0.01) versus control.Ferritin and C-reactive protein serum concentration were significantly higher only in MCD6 group. Our study suggests that MCD diet induces a progressive rise in nitrosative stress in the liver. Additionally, the most prominent decrease in liver antioxidative capacity is in the fourth week, which implies that application of antioxidants would be most suitable in this period, in order to prevent nonalcoholic steatohepatitis but not the initial NAFLD phase.
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Fongsamut, Kanokkarn, Monsit Tanasittikosol, and Mingkhuan Phaksunchai. "Effectiveness of the simulation-based learning (SBL) assisted with scaffolding approach to address students’ misconceptions about projectile motion." Physics Education 58, no. 2 (December 14, 2022): 025002. http://dx.doi.org/10.1088/1361-6552/aca57d.

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Abstract This research studied the effectiveness of the simulation-based learning assisted with scaffolding approach to address students’ misconceptions (MCs) about projectile motion. The five MCs were related to the direction of the force acting on an object (MC1), the acceleration of an object at the top of the trajectory (MC2), the directions of velocity and acceleration during projectile motion (MC3), the time of flight of objects (MC4), and the relationship between the range of projectile motion and angle of projection (MC5). This study was a pre-experimental design using both quantitative and qualitative data. The sample comprised 35 tenth-grade Thai high school students who were chosen using the cluster sampling technique. The teaching method consisted of three steps: a briefing, simulation, and debriefing. Each step was assisted with scaffolding to guide and help the students. The MCs tests consisted of five multiple-choice questions with a four-tier diagnostic test, and the tests were used as a pre-test, end-of-class test, and end-of-topic test. Six semi-structured interview questions were used to obtain in-depth data. The results indicated that MC1, MC2, MC3, MC4, and MC5 were addressed by 11.1%, 85.7%, 57.2%, 57.2%, and 61.5%, respectively, at the end-of-topic test. Students who had MCs in the pre-test changed their understanding of the concepts in MC2, MC3, MC4, and MC5 by 57.1%, 14.3%, 28.6%, and 53.8%, respectively. None of the MC students in MC1 understood the concept at the end-of-topic test. Nevertheless, the overall results showed increased students’ understanding of all conceptions.
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Abdellah, Marwa Mahmoud, Hatem Gamal Ammar, Mohamed Anbar, Engy Mohammed Mostafa, Mahmoud Mohamed Farouk, Khulood Sayed, Alahmady Hammad Alsmman, and Mohamed Gamal Elghobaier. "Corneal Endothelial Cell Density and Morphology in Healthy Egyptian Eyes." Journal of Ophthalmology 2019 (February 24, 2019): 1–8. http://dx.doi.org/10.1155/2019/6370241.

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Purpose. To evaluate the corneal endothelial cell density and morphology in normal Egyptian eyes. Methods. In total, 568 healthy eyes of 568 Egyptian volunteers aged 20 to 85 years were examined using noncontact specular microscopy for the central corneal thickness (CCT), mean endothelial cell density (MCD), coefficient of variation (CV) in cell area, mean cell area (MCA), and hexagonal cell (Hex) percentage. Variables were compared between sexes and between different age groups. Results. The mean CCT, MCD, and MCA were 514.45 ± 43.04 μm, 2647.50 ± 382.62 cells/mm2, and 390.59 ± 149.94 μm2, respectively. MCD and MCA showed no significant differences between men and women (P=0.171 and 0.099, respectively), whereas CV (%) and Hex (%) showed significant differences (P=0.024 and 0.015, respectively). CCT (P=0.007, r = −0.113) and MCD (P<0.001, r = −0.357) exhibited a significant negative correlation with age, whereas CV (%) (P<0.001, r = 0.341) and MCA (P=0.008, r = 0.111) exhibited a significant positive correlation. The mean rate of endothelial cell loss from 20 to 85 years of age was 0.3% per year. Conclusions. Our results provide normative data for the corneal endothelium in healthy Egyptian eyes, thus increasing the knowledge base for corneal endothelial cell parameters in healthy Egyptian eyes. Furthermore, our findings can be used as baseline values for comparisons between Egyptian and other populations and for studies of the endothelial cell reserve and capacity for intraocular surgery and corneal transplantation.
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Uski, P., A. Ellman, I. Laine, L. Hillman, and J. Nieminen. "Model-Based Definition Accelerates Product Life Cycle in Manufacturing and Inspection Phase – Experiment of Machined One-Off Production." Proceedings of the Design Society 2 (May 2022): 643–52. http://dx.doi.org/10.1017/pds.2022.66.

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AbstractThe paper focuses on comparative experiment on manufacturing and inspection of two different prismatic one-off parts, which have different complexity. Our experiment shows that transforming product definition method from the Drawing Centric Definition (DCD) to the Model Centric Definition (MCD) enables 28%-29% time savings in manufacturing and inspection phases of machined one-off part's life cycle. Furthermore, transition from MCD to Model-Based Definition (MBD) enables 5%-9% time savings, respectively. Applying of MBD enables more time savings in complex part compared to a less complex part.
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Arıcı, Ceyhun, Osman Sevki Arslan, and Funda Dikkaya. "Corneal Endothelial Cell Density and Morphology in Healthy Turkish Eyes." Journal of Ophthalmology 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/852624.

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Purpose. To describe the normative values of corneal endothelial cell density, morphology, and central corneal thickness in healthy Turkish eyes.Methods. Specular microscopy was performed in 252 eyes of 126 healthy volunteers (M : F, 42 : 84). Parameters studied included mean endothelial cell density (MCD), mean cell area (MCA), coefficient of variation (CV) in cell size, percentage of hexagonal cells, and central corneal thickness (CCT).Results. The mean age of volunteers was44.3±13.5(range, 20 to 70) years. There was a statistically significant decrease in MCD (P<0.001; correlation, −0.388) and percentage of hexagonal cells, (P<0.001; correlation, −0.199) with age. There was also a statistically significant increase in MCA (P<0.001; correlation, 0.363) with increasing age. There was no statistically significant difference in MCD, MCA, CV in cell size, percentage of hexagonal cells, and CCT between genders and there was also no significant difference in these parameters between fellow eyes of subjects.Conclusions. Normotive data for the endothelium in the Turkish population are reported. Endothelial cell density in the Turkish eyes is less than that described in the Japanese, American, Chinese, and Filipino eyes and higher than that described in Indian, Thai, and Iranian eyes.
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Cho, Won-Hee, Seon-Hwa Park, Seul-Ki Choi, Su Woong Jung, Kyung Hwan Jeong, Yang-Gyun Kim, Ju-Young Moon, et al. "Characterization of IgA Deposition in the Kidney of Patients with IgA Nephropathy and Minimal Change Disease." Journal of Clinical Medicine 9, no. 8 (August 12, 2020): 2619. http://dx.doi.org/10.3390/jcm9082619.

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Approximately 5% of patients with IgA nephropathy (IgAN) exhibit mild mesangial lesions with acute onset nephrotic syndrome and diffuse foot process effacement representative of minimal change disease (MCD). It is not clear whether these unusual cases of IgAN with MCD (IgAN-MCD) are variant types of IgAN or coincidental deposition of IgA in patients with MCD. In a retrospective multicenter cohort study of 18 hospitals in Korea, we analyzed 46 patients with IgAN-MCD. Patients with endocapillary proliferation, segmental sclerosis, and crescent were excluded, and the clinical features and prognosis of IgAN-MCD were compared with those of pure MCD. In addition, we performed galactose-deficient IgA1 (KM55) staining to characterize IgAN-MCD. Among the 21,697 patients with glomerulonephritis enrolled in the database, 46 patients (0.21%) were diagnosed with IgAN-MCD, and 1610 patients (7.4%) with pure MCD. The 46 patients with IgAN-MCD accounted for 0.6% of primary IgAN patients (n = 7584). There was no difference in prognosis between patients with IgAN-MCD and those with only MCD. IgA and KM55 showed double positivity in all patients with IgAN-MCD (n = 4) or primary IgAN (n = 5) under double immunofluorescent staining. However, in four patients with lupus nephritis, mesangial IgA was deposited, but galactose-deficient-IgA1 (Gd-IgA1) was not. These findings suggest that IgAN-MCD is a dual glomerulopathy in which MCD was superimposed on possibly indolent IgAN. We confirmed by KM55 staining that IgAN-MCD is true IgAN, enabling better characterizations of the disease. Furthermore, IgAN-MCD shows a good prognosis when treated according to the usual MCD treatment modality.
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Vesković, Milena, Milica Labudović-Borović, Ivan Zaletel, Jelena Rakočević, Dušan Mladenović, Bojan Jorgačević, Danijela Vučević, and Tatjana Radosavljević. "The Effects of Betaine on the Nuclear Fractal Dimension, Chromatin Texture, and Proliferative Activity in Hepatocytes in Mouse Model of Nonalcoholic Fatty Liver Disease." Microscopy and Microanalysis 24, no. 2 (January 19, 2018): 132–38. http://dx.doi.org/10.1017/s1431927617012806.

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AbstractThe effects of betaine on hepatocytes chromatin architecture changes were examined by using fractal and gray-level co-occurrence matrix (GLCM) analysis in methionine/choline-deficient (MCD) diet-induced, nonalcoholic fatty liver disease (NAFLD). Male C57BL/6 mice were divided into groups: (1) Control: standard diet; (2) BET: standard diet and betaine supplementation through drinking water (solution 1.5%); (3) MCD group: MCD diet for 6 weeks; (4) MCD+BET: fed with MCD diet + betaine for 6 weeks. Liver tissue was collected for histopathology, immunohistochemistry, and determination of fractal dimension and GLCM parameters. MCD diet induced diffuse micro- and macrovesicular steatosis accompanied with increased Ki67-positive hepatocyte nuclei. Steatosis and Ki67 immunopositivity were less prominent in the MCD+BET group compared with the MCD group. Angular second moment (ASM) and inverse difference moment (IDM) (textural homogeneity markers) were significantly increased in the MCD+BET group versus the MCD group (p<0.001), even though no difference between the MCD and the control group was evident. Heterogeneity parameters, contrast, and correlation were significantly increased in the MCD group versus the control (p<0.001). On the other hand, betaine treatment significantly reduced correlation, contrast, and entropy compared with the MCD group (p<0.001). Betaine attenuated MCD diet-induced NAFLD by reducing fat accumulation and inhibiting hepatocyte proliferation. Betaine supplementation increased nuclear homogeneity and chromatin complexity with reduction of entropy, contrast, and correlation.
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Vesković, Milena, Milica Labudović-Borović, Dušan Mladenović, Jelena Jadžić, Bojan Jorgačević, Dušan Vukićević, Danijela Vučević, and Tatjana Radosavljević. "Effect of Betaine Supplementation on Liver Tissue and Ultrastructural Changes in Methionine–Choline-Deficient Diet-Induced NAFLD." Microscopy and Microanalysis 26, no. 5 (August 12, 2020): 997–1006. http://dx.doi.org/10.1017/s1431927620024265.

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AbstractNonalcoholic fatty liver disease (NAFLD) represents a hepatic manifestation of metabolic syndrome. The aim of this study was to examine the effect of betaine on ultrastructural changes in the mouse liver with methionine- and choline-deficient (MCD) diet-induced NAFLD. Male C57BL/6 mice were divided into groups: Control—fed with standard chow, BET—standard chow supplemented with betaine (1.5% w/v drinking water), MCD—fed with MCD diet, and MCD + BET—MCD diet with betaine supplementation for 6 weeks. Liver samples were taken for pathohistology and transmission electron microscopy. The MCD diet-induced steatosis, inflammation, and balloon-altered hepatocytes were alleviated by betaine. MCD diet induced an increase in mitochondrial size versus the control group (p < 0.01), which was decreased in the betaine-treated group. In the MCD diet-fed group, the total mitochondrial count decreased versus the control group (p < 0.01), while it increased in the MCD + BET group versus MCD (p < 0.01). Electron microscopy showed an increase in the number of autophagosomes in the MCD and MCD + BET group versus control, and a significant difference in autophagosomes number was detected in the MCD + BET group by comparison with the MCD diet-treated group (p < 0.05). Betaine decreases the number of enlarged mitochondria, alleviates steatosis, and increases the number of autophagosomes in the liver of mice with NAFLD.
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Young, Martin E., Gary W. Goodwin, Jun Ying, Patrick Guthrie, Christopher R. Wilson, Frank A. Laws, and Heinrich Taegtmeyer. "Regulation of cardiac and skeletal muscle malonyl-CoA decarboxylase by fatty acids." American Journal of Physiology-Endocrinology and Metabolism 280, no. 3 (March 1, 2001): E471—E479. http://dx.doi.org/10.1152/ajpendo.2001.280.3.e471.

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Malonyl-CoA decarboxylase (MCD) catalyzes the degradation of malonyl-CoA, an important modulator of fatty acid oxidation. We hypothesized that increased fatty acid availability would increase the expression and activity of heart and skeletal muscle MCD, thereby promoting fatty acid utilization. The results show that high-fat feeding, fasting, and streptozotocin-induced diabetes all significantly increased the plasma concentration of nonesterified fatty acids, with a concomitant increase in both rat heart and skeletal muscle MCD mRNA. Upon refeeding of fasted animals, MCD expression returned to basal levels. Fatty acids are known to activate peroxisome proliferator-activated receptor-α (PPARα). Specific PPARα stimulation, through Wy-14643 treatment, significantly increased the expression of MCD in heart and skeletal muscle. Troglitazone, a specific PPARγ agonist, decreased MCD expression. The sensitivity of MCD induction by fatty acids and Wy-14643 was soleus > extensor digitorum longus > heart. High plasma fatty acids consistently increased MCD activity only in solei, whereas MCD activity in the heart actually decreased with high-fat feeding. Pressure overload-induced cardiac hypertrophy, in which PPARα expression is decreased (and fatty acid oxidation is decreased), resulted in decreased MCD mRNA and activity, an effect that was dependent on fatty acids. The results suggest that fatty acids induce the expression of MCD in rat heart and skeletal muscle. Additional posttranscriptional mechanisms regulating MCD activity appear to exist.
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DYCK, Jason R. B., Luc G. BERTHIAUME, Panakkezhum D. THOMAS, Paul F. KANTOR, Amy J. BARR, Rick BARR, Dyal SINGH, et al. "Characterization of rat liver malonyl-CoA decarboxylase and the study of its role in regulating fatty acid metabolism." Biochemical Journal 350, no. 2 (August 23, 2000): 599–608. http://dx.doi.org/10.1042/bj3500599.

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In the liver, malonyl-CoA is central to many cellular processes, including both fatty acid biosynthesis and oxidation. Malonyl-CoA decarboxylase (MCD) is involved in the control of cellular malonyl-CoA levels, and functions to decarboxylate malonyl-CoA to acetyl-CoA. MCD may play an essential role in regulating energy utilization in the liver by regulating malonyl-CoA levels in response to various nutritional or pathological states. The purpose of the present study was to investigate the role of liver MCD in the regulation of fatty acid oxidation in situations where lipid metabolism is altered. A single MCD enzyme of molecular mass 50.7kDa was purified from rat liver using a sequential column chromatography procedure and the cDNA was subsequently cloned and sequenced. The liver MCD cDNA was identical to rat pancreatic β-cell MCD cDNA, and contained two potential translational start sites, producing proteins of 50.7kDa and 54.7kDa. Western blot analysis using polyclonal antibodies generated against rat liver MCD showed that the 50.7kDa isoform of MCD is most abundant in heart and liver, and of relatively low abundance in skeletal muscle (despite elevated MCD transcript levels in skeletal muscle). Tissue distribution experiments demonstrated that the pancreas is the only rat tissue so far identified that contains both the 50.7 kDa and 54.7kDa isoforms of MCD. In addition, transfection of the full-length rat liver MCD cDNA into COS cells produced two isoforms of MCD. This indicated either that both initiating methionines are functionally active, generating two proteins, or that the 54.7kDa isoform is the only MCD protein translated and removal of the putative mitochondrial targeting pre-sequence generates a protein of approx. 50.7kDa in size. To address this, we transiently transfected a mutated MCD expression plasmid (second ATG to GCG) into COS-7 cells and performed Western blot analysis using our anti-MCD antibody. Western blot analysis revealed that two isoforms of MCD were still present, demonstrating that the second ATG may not be responsible for translation of the 50.7kDa isoform of MCD. These data also suggest that the smaller isoform of MCD may originate from intracellular processing. To ascertain the functional role of the 50.7kDa isoform of rat liver MCD, we measured liver MCD activity and expression in rats subjected to conditions which are known to alter fatty acid metabolism. The activity of MCD was significantly elevated under conditions in which hepatic fatty acid oxidation is known to increase, such as streptozotocin-induced diabetes or following a 48h fast. A 2-fold increase in expression was observed in the streptozotocin-diabetic rats compared with control rats. In addition, MCD activity was shown to be enhanced by alkaline phosphatase treatment, suggesting phosphorylation-related control of the enzyme. Taken together, our data demonstrate that rat liver expresses a 50.7kDa form of MCD which does not originate from the second methionine of the cDNA sequence. This MCD is regulated by at least two mechanisms (only one of which is phosphorylation), and its activity and expression are increased under conditions where fatty acid oxidation increases.
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Dissertations / Theses on the topic "MCD"

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Enseroth, Timo [Verfasser]. "Konstruktion und Validierung der MCD-Skala zur Erfassung unterschwelliger organischer Psychosyndrome (Minimale Cerebrale Dysfunktion, MCD) im Erwachsenenalter / Timo Enseroth." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2011. http://d-nb.info/1026264200/34.

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Arvidsson, Ann-Christine. "Framtagningav miljöbedömningsmetod av leverantörer : arbetet utfört hos Parker Hannifin AB MCD." Thesis, University West, Department of Informatics and Mathematics, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-889.

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Singer, R. "Matrix induced effects in the MCD spectra of isolated metal atoms." Thesis, University of East Anglia, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374272.

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Wolff, Pamela A. Carleton University Dissertation Chemistry. "Electronic and magnetic hypersensitivity in the MCD spectra of lanthanide complexes." Ottawa, 1990.

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Irvine, Alan David. "Mutation analysis in human keratin diseases." Thesis, Queen's University Belfast, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268237.

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Hualpa, Benavente Flor Patricia. "Componentes principales mediante el método robusto MCD: Matriz de covarianzas de determinante mínimo." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2012. https://hdl.handle.net/20.500.12672/3136.

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Este trabajo de investigación aborda el problema de falta de robustez, mediante el reemplazo de la matriz de covarianzas obtenida con el método clásico, por la matriz de covarianzas obtenida con el método robusto MCD (Todorov y Filzmoser, 2009). El método robusto MCD: Minimun Covariance Determinant, consiste en realizar las estimaciones para el vector de medias y la matriz de covarianzas a partir de la selección de una submuestra obtenida del remuestreo del conjunto de datos en estudio, cuya característica principal es que tiene la matriz de covarianzas con determinante mínimo. Muchas veces, el análisis estadístico en presencia de datos atípicos, mediante métodos clásicos, puede llevar a conclusiones erróneas debido a la sensibilidad de dichos métodos, por ello el objetivo del presente trabajo es presentar la metodología de los estimadores MCD, a fin de conseguir una “matriz de covarianzas robustificada” la cual será utilizada para realizar el Análisis de Componentes Principales en conjuntos de datos con presencia de observaciones atípicas. Se ilustra la metodología de la teoría y la aplicación para dos conjuntos de datos, resultados de investigaciones en la Botánica (Quinteros, 2010 y Gómez, et. al., 2008), se analiza el comportamiento de las Componentes Principales con la metodología MCD y se compara con la metodología clásica. Se determina que las Componentes Principales obtenidas por el método de MCD permiten encontrar mejores indicadores para los conjuntos de datos que tienen valores atípicos. -- Palabras clave: Minimum Covariance Determinant, MCD, Componentes Principales, Estimación Robusta, Matriz de Varianzas y Covarianzas.
--- This research addresses the problem of lack of robustness, by replacing the covariance matrix obtained with the classical method for the covariance matrix obtained with the robust MCD method (Todorov and Filzmoser, 2009). The robust method MCD: Minimun Covariance Determinant, involves making estimates for the mean vector and covariance matrix from the selection of a subsample obtained from the resampling of the data set under study, whose main characteristic is that it has the covariance matrix with the minimum determinant. Many times, the statistical analysis in the presence of outliers, by standard methods, can be misleading because of the sensitivity of these methods, which is why the objective of this paper is to present the methodology of the MCD estimators in order to achieve the "robustified covariance matrix" which will be used to perform Principal Component Analysis on data sets with the presence of outliers. We illustrate the methodology of the theory and application, for two sets of data, research results in the Botany (Quinteros, 2010 and Gomez, et. Al., 2008), we analyze the behavior of the Principal Components with the MCD method and we compare it to the classic methodology. It is determined that the principal components obtained by the MCD method allows to find better indicators for data sets with outliers. -- Keywords: Minimum Covariance Determinant, MCD, Principal Components, Robust Estimation, Scatter Matrix.
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Toriguchi, Kan. "CHOP deficiency attenuates steatohepatitis, fibrosis and carcinogenesis in mice fed an MCD diet." Kyoto University, 2014. http://hdl.handle.net/2433/188659.

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Westphal, Anne [Verfasser]. "UV/Vis, MCD and EPR Spectra of Mononuclear Manganese and Molybdenum Complexes / Anne Westphal." Kiel : Universitätsbibliothek Kiel, 2014. http://d-nb.info/1053653530/34.

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Warnke, Max Holger [Verfasser]. "Klinische Korrelate von Indikatoren komplexer Teilleistungsstörungen bzw. Minimaler Cerebraler Dysfunktion (MCD) / Max Holger Warnke." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2012. http://d-nb.info/1030382522/34.

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Gonzales, de Olarte Efraín. "La Matriz de Capacidades y Desempeños (MCD) y el Algoritmo del Desarrollo Humano (ADH)." Economía, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/117871.

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Given that human development is a complex process involving multiple components and determiningfactors, multidimensional indicators are needed. On the basis of the extensive literatureon the subject, we advance two new indicators: the Matrix of Capabilities and Functioning(MCF), and the Algorithm of Human Development (HDA).The MCF is composed of vectors of capabilities and functionings, based on Sen’s idea of RefinedFunctionings. It is based in a matricial framework, both static and dynamic. The main purposeof constructing this index is to study how different sets of capabilities relate to alternativefunctionings, to produce diverse outcomes.The Human Development Algorithm (HAD) is a multidimensional index concerning the setof goods and services needed to complete a life cycle. The HDA is a socio-economic contextindicator. It is composed of the main «satisfactors» or basic goods and services needed: food,health, education, housing, social security, decent employment and retirement programs, thatmight be available to all throughout of life cycle. This indicator shows the material progressreached by each country or region as well the institutional organization, private and public, andthe degree of social cohesion and solidarity.
Dado que el desarrollo humano es un proceso complejo que tiene múltiples componentes ydeterminantes, es necesario tener indicadores multidimensionales tales como la Matriz de Capacidadesy Desempeños (MCD) y el Algoritmo del Desarrollo Humano (ADH).El MCD está compuesto de vectores de capacidades y de desempeños, basado en la idea de Sensobre desempeños refinados. Está basado en un marco conceptual matricial, tanto estático comodinámico. El propósito principal de la construcción del índice es estudiar cómo diferentes conjuntosde capacidades con desempeños pueden producir distintos resultados.El ADH es un índice multidimensional relacionado con el conjunto de bienes y servicios que senecesitan para completar un ciclo de vida. El ADH es un indicador de contexto socioeconómico.Está compuesto de los principales satisfactores o bienes y servicios básicos que se requieren: alimentos,salud, educación, vivienda, seguridad social, empleo decente y sistema de pensiones, quedeben estar disponibles durante todo el ciclo de vida. Este indicador muestra el progreso materialalcanzado por cada país o región, tanto como la organización institucional pública y privada, yel grado de cohesión social.
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Books on the topic "MCD"

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Wilson, Ross. "Skyhorse: Kells. For V. McD.". [Belfast]: Arts Council of Northern Ireland, 1986.

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Chopra, Neelima. Early childhood education in MCD schools. Delhi, India: Global Books Organisation, 2015.

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Graham, Robin G. Mcd saturation studies of some matrix isolated paramagnets. Norwich: University of East Anglia, 1988.

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Mackenberg, Hubert. Die Untersuchung sozialkognitiver Fähigkeiten bei Kindern mit MCD-Diagnose. Münster: Lit, 1991.

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Building Materials and Technology Promotion Council (India). Seismic retrofitting of MCD school buildings at New Delhi: BMTPC's initiative. New Delhi: Building Materials & Technology Promotion Council, Ministry of Housing & Urban Poverty Alleviation, Government of India, 2012.

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Brillet, Jean Louis. Win-MCD: Simulation sous Windows de la maquette économique micro-DMS. [Paris]: INSEE, 1997.

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MCD 2007 (2007 Warsaw, Poland). Mining complex data: ECML/PKDD 2007 third international workshop, MCD 2007, Warsaw, Poland, September 17-21, 2007 : revised selected papers. Berlin: Springer, 2008.

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Zbigniew, Raś, Tsumoto Shusaku 1963-, Zighed Djamel A. 1955-, and ECML/PKDD 2007 (2007 : Warsaw, Poland), eds. Mining complex data: ECML/PKDD 2007 third international workshop, MCD 2007, Warsaw, Poland, September 17-21, 2007 : revised selected papers. Berlin: Springer, 2008.

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Douglas, Annie. A mother in Israel: The life story of Mrs. Annie Douglas and a tribute by Rev. J. McD. Kerr, Toronto, Canada. Oklahoma City, Okla: Charles Edwin Jones, 2002.

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Cassidy, Wayne. MCAD/MCSD Visual Basic.NET Web applications study guide: (exam 70-305). New York: McGraw-Hill Osborne, 2002.

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Book chapters on the topic "MCD"

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Oette, Mark, Marvin J. Stone, Hendrik P. N. Scholl, Peter Charbel Issa, Monika Fleckenstein, Steffen Schmitz-Valckenberg, Frank G. Holz, et al. "MCD." In Encyclopedia of Molecular Mechanisms of Disease, 1270. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_7907.

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Schmidt, Hans-Reinhard. "Die Wiedergeburt von MCD." In Ich lerne wie ein Zombie, 191–95. Wiesbaden: Springer Fachmedien Wiesbaden, 2019. http://dx.doi.org/10.1007/978-3-658-14130-1_13.

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Gupta, Pallav, and Ramesh K. Gupta. "Minimal Change Disease (MCD)." In Pathology of Glomerular Diseases, 13–16. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-1430-0_2.

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Selvam, K. C. "Time-Division MCD without Reference." In Multiplier-Cum-Divider Circuits, 155–72. New York: CRC Press, 2021. http://dx.doi.org/10.1201/9781003168515-11.

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Willems, G., G. Pison, P. J. Rousseeuw, and S. Van Aelst. "A Hotelling Test Based on MCD." In Compstat, 117–22. Heidelberg: Physica-Verlag HD, 2002. http://dx.doi.org/10.1007/978-3-642-57489-4_12.

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Selvam, K. C. "Triangular Wave-Referenced MCD with Multiplexers." In Multiplier-Cum-Divider Circuits, 65–76. New York: CRC Press, 2021. http://dx.doi.org/10.1201/9781003168515-6.

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Pison, G., S. Van Aelst, and G. Willems. "Small Sample Corrections for LTS and MCD." In Developments in Robust Statistics, 330–43. Heidelberg: Physica-Verlag HD, 2003. http://dx.doi.org/10.1007/978-3-642-57338-5_29.

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Selvam, K. C. "Triangular Wave-Referenced MCD with Analog Switches." In Multiplier-Cum-Divider Circuits, 115–28. New York: CRC Press, 2021. http://dx.doi.org/10.1201/9781003168515-9.

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Buku, Angeliki, Christian Birr, and Diana Gazis. "Synthetic analogs of mast cell degranulating (MCD) peptide." In Peptides 1990, 746–47. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3034-9_309.

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Wright, John R., Wayne A. Hendrickson, Shigemasa Osaki, and Gordon T. James. "Circular Dichroism (CD) and Magnetic Circular Dichroism (MCD)." In Physical Methods for Inorganic Biochemistry, 311–28. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-4997-6_9.

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Conference papers on the topic "MCD"

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Chen, Jiazi. "Immobilized lipase in the synthesis of high purity medium chain diacylglycerols using a bubble column reactor: Characterization and application." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/vdem7919.

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Novozym® 435, an immobilized lipase from Candida antarctica B. (CALB), was used as a biocatalyst for the synthesis of high purity medium chain diacylglycerol (MCD) in a bubble column reactor. In this work, the properties of the MCD produced were characterized followed by determining its practical application as an emulsifier in water-in-oil (W/O) emulsion. Two types of MCDs, namely, dicaprylin (C8-DAG) and dicaprin (C10-DAG), were prepared through enzymatic esterification using the following conditions: 5% Novozym® 435, 2.5% deionized water, 60 °C for 30 min followed by purification. A single-step molecular distillation (MD) (100–140 °C, 0.1 Pa, 300 rpm) was performed and comparison was made to that of a double-step purification with MD followed by silica gel column chromatography technique (MD + SGCC). Crude C8-DAG and C10-DAG with DAG concentration of 41% and 44%, respectively, were obtained via the immobilized enzyme catalyzing reaction. Post purification via MD, the concentrations of C8-DAG and C10-DAG were increased to 80% and 83%, respectively. Both MCDs had purity of 99% after the MD + SGCC purification step. Although Novozym® 435 is a non-specific lipase, higher ratios of 1,3-DAG to 1,2-DAG were acquired. Via MD, the ratios of 1,3-DAG to 1,2-DAG in C8-DAG and C10-DAG were 5.8:1 and 7.3:1, respectively. MCDs that were purified using MD + SGCC were found to contain 1,3-DAG to 1,2-DAG ratios of 8.8:1 and 9.8:1 in C8-DAG and C10-DAG, respectively. The crystallization and melting peaks were shifted to higher temperature regions as the purity of the MCD was increased. Dense needle-like crystals were observed in MCDs with high purity. Addition of 5% C8-DAG and C10-DAG as emulsifier together in the presence of 9% of hydrogenated soybean oil produced stable W/O emulsion with particle size of 18 mm and 10 mm, respectively.
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"MCD 2008 Message and Committee." In 2008 IEEE International Conference on Data Mining Workshops. IEEE, 2008. http://dx.doi.org/10.1109/icdmw.2008.110.

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Johnson, D. E., D. P. Poulios, N. P. Bigelow, and J. P. Spoonhower. "Optical absorption and magnetic circular dichroism of ER(3+)-doped aluminosilicate glasses." In Bragg Gratings, Photosensitivity, and Poling in Glass Fibers and Waveguides. Washington, D.C.: Optica Publishing Group, 1997. http://dx.doi.org/10.1364/bgppf.1997.jsue.27.

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The magnetic circular dichroism (MCD) and optical absorption spectra are reported for varying erbium(3+) concentrations in aluminosilicate glasses. Visible MCD data are obtained at a field strength of 1.8 Tesla and at a base temperature of 1.7 K. The temperature dependence in the range up to 300 K is also studied. A striking result of this work is the drastic change in both shape and position of many of the MCD absorption bands with erbium(3+) concentration. These changes give insight into the nature of the erbium ion’s crystal field and thus its local environment. The MCD (or Faraday) parameters are determined via the method of moments.
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Zhong, Xueqi, Zehua Bao, and Jianzhong Li. "Investigation of seismic response of rocking column with a novel mechanical connection device." In IABSE Congress, Ghent 2021: Structural Engineering for Future Societal Needs. Zurich, Switzerland: International Association for Bridge and Structural Engineering (IABSE), 2021. http://dx.doi.org/10.2749/ghent.2021.0266.

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<p>The rocking column is a kind of excellent seismic-resistant and resilient structure. However, during the rocking process, local pressure on the rocking interface may result in spalling and crushing of concrete at the toe. In order to reduce the local damage of the rocking interface, as well as accelerate the connection between prefabricated column and footing, a kind of mechanical connection device (MCD) was proposed in this research. The MCD is used at the bottom of column and ofters rapid connection of the column to the footing. The recentering force of MCD column is provided by PT strands and axial force of superstructure, and the energy dissipation is provided by U-shaped dissipaters. A simplified analytical method based on interface section analysis is proposed to study the hysteretic behavior of column with MCD. The results suggest that the MCD column has stable hysteretic behavior and can achieve small residual drift after earthquakes by appropriate design.</p>
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Zhong, Xueqi, Zehua Bao, and Jianzhong Li. "Investigation of seismic response of rocking column with a novel mechanical connection device." In IABSE Congress, Ghent 2021: Structural Engineering for Future Societal Needs. Zurich, Switzerland: International Association for Bridge and Structural Engineering (IABSE), 2021. http://dx.doi.org/10.2749/ghent.2021.0266.

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<p>The rocking column is a kind of excellent seismic-resistant and resilient structure. However, during the rocking process, local pressure on the rocking interface may result in spalling and crushing of concrete at the toe. In order to reduce the local damage of the rocking interface, as well as accelerate the connection between prefabricated column and footing, a kind of mechanical connection device (MCD) was proposed in this research. The MCD is used at the bottom of column and ofters rapid connection of the column to the footing. The recentering force of MCD column is provided by PT strands and axial force of superstructure, and the energy dissipation is provided by U-shaped dissipaters. A simplified analytical method based on interface section analysis is proposed to study the hysteretic behavior of column with MCD. The results suggest that the MCD column has stable hysteretic behavior and can achieve small residual drift after earthquakes by appropriate design.</p>
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Gudavalli, Maruti Ram, Vikas Yadav, Robert Vining, Michael Seidman, Stacie Salsbury, Paige Morgenthal, Avinash Patwardhan, and Christine Goertz. "Development of Force-Feedback Technology for Training Clinicians to Deliver Manual Cervical Distraction." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-64509.

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Objective: Neck pain is a prevalent musculoskeletal (MSK) complaint and costly societal burden. Doctors of chiropractic (DCs) provide manual therapies for neck pain patients to relieve discomfort and improve physical function. Manual cervical distraction (MCD) is a chiropractic procedure for neck pain. During MCD, the patient lies face down on a specially designed chiropractic table. The DC gently moves the head and neck in a cephalic direction while holding a gentle broad manual contact over the posterior neck, to create traction effects. MCD traction force profiles vary between clinicians making standardization of treatment delivery challenging. This paper reports on a bioengineering technology developed to provide clinicians with auditory and graphical feedback on the magnitude of cervical traction forces applied during MCD to simulated patients during training for a randomized controlled trial (RCT). Methods: The Cox flexion-distraction chiropractic table is designed with a moveable headpiece. The table allows for long axis horizontal movement of the head and neck, while the patient’s trunk and legs rest on fixed table sections. We instrument-modified this table with three-dimensional force transducers to measure the traction forces applied by the doctor. Motion Monitor software collects data from force transducers. The software displays the magnitude of traction forces graphically as a function of time. Real-time audible feedback produces a steady tone when measured traction forces are <20N, no tone when forces range between 20–50N, and an audible tone when forces exceed 50N. Peer debriefing from simulated patients reinforces traction force data from the bioengineering technology. Results: We used audible and graphical feedback to train and certify DCs to apply traction forces to the cervical spine of simulated patients within three specific ranges. This technology supports a RCT designed to assess the ability of clinicians to deliver MCD within specified force ranges to patients randomized to different force dosages as an intervention. Future applications may include training chiropractic students and clinicians to deliver the MCD treatment.
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Yu, Philip S., and Jiawei Zhang. "MCD: Mutual Clustering across Multiple Social Networks." In 2015 IEEE International Congress on Big Data (BigData Congress). IEEE, 2015. http://dx.doi.org/10.1109/bigdatacongress.2015.127.

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Fernandes, Andre Alonso, Danilo Signorini Gozzi, Emmanuel Franco Nogueira, Felipe de Souza Terra, Guilherme Sirqueira Vanni, and Rafael Schettini Frazão Filho. "MPD/MCD Offshore Application on a Dynamic Positioning Rig." In SPE/IADC Managed Pressure Drilling and Underbalanced Operations Conference & Exhibition. Society of Petroleum Engineers, 2015. http://dx.doi.org/10.2118/173825-ms.

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Kaiser, Jurgen, Dirk Meister, Viktor Gottfried, and Andre Brinkmann. "MCD: Overcoming the Data Download Bottleneck in Data Centers." In 2013 IEEE 8th International Conference on Networking, Architecture, and Storage (NAS). IEEE, 2013. http://dx.doi.org/10.1109/nas.2013.18.

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Santos, Justino Duarte, Romuere R. V. Silva, and Rodrigo M. S. Veras. "Application of geostatistical functions and deep features to kidney biopsy images to differentiate focal segmental glomerulosclerosis from minimal change disease." In Conference on Graphics, Patterns and Images. Sociedade Brasileira de Computação, 2020. http://dx.doi.org/10.5753/sibgrapi.est.2020.12984.

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Chronic kidney diseases arise from acute or intermittent pathologies that have not been adequately treated, such as minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS). The accurate identification of these two diseases is of paramount importance, because their treatments and prognoses are different. Thus, we propose a method that is capable of differentiating MCD from FSGS based on images from pathological examinations. In the proposed method, we use four pre-trained convolutional neural networks and geostatistical functions to extract image features. Of the 8,720 extracted features, we selected 94 based on mutual information criteria, and in the classification step, we used a random forest classifier. The proposed method obtained an accuracy of 94.3% and Kappa index of 87.9%, a level that is regarded as “almost perfect”, confirming that our method is very promising.
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Reports on the topic "MCD"

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Kuhajda, Francis P. Malonyl-CoA Decarboxylase (MCD) as a Potential Therapeutic Target for Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, May 2008. http://dx.doi.org/10.21236/ada508649.

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Petersen, Kirsten Elisa. Danske daginstitutioners indsatser og disses betydninger for pædagogisk personale, børn og familier under COVID-19 pandemien 2020/2021. Aarhus University Library, 2021. http://dx.doi.org/10.7146/aul.420.

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Denne rapport præsenterer en række centrale resultater af et forskningsprojekt med fokus på daginstitutioners indsatser og betydning for pædagogisk personale, børn og familier under COVID-19 pandemien i Danmark. Forskningsprojektet har indsamlet data i perioden april 2020 til august 2020, og særligt i perioden fra midt april til juni, hvor alle landets daginstitutioner genåbnede efter cirka en måneds nedlukning af landets offentlige institutioner som følge af regeringens retningslinjer. Der er ligeledes indsamlet data i perioden august til oktober 2020, og igen i perioden januar til februar 2021. Der er således tale om tre empiriske nedslag hen over cirka et år af pandemiens forløb i relation til daginstitutionsledere og pædagogisk personale i landets daginstitutioner. De data, der ligger til grund for denne rapport, omfatter en spørgeskemaundersøgelse rettet mod daginstitutionsledere og en spørgeskemaundersøgelse rettet mod pædagogisk personale i daginstitutioner, geografisk fordelt over hele landet. Fælles for spørgeskemaundersøgelserne er et fokus på at udforske, hvordan daginstitutioner har arbejdet under COVID-19 pandemien, dels under selve nedlukningen i marts-april, hvor flere af landets daginstitutioner har fungeret som nødpasning, særligt for forældre med kritiske samfundsfunktioner, og dels under genåbningsfaserne, der officielt blev påbegyndt i midten af april og især har forløbet hen over forår og tidlig sommer 2020. Derudover er der ad to omgange foretaget en række forskningsinterview med daginstitutionsledere. I første omgang blev der foretaget 10 forskningsinterview i perioden august til november 2020, og i anden omgang er der foretaget 8 forskningsinterview med daginstitutionsledere fordelt på landets daginstitutioner omfattende perioden januar til februar 2021. Formålet med dette forskningsprojekt har været at kortlægge og udforske, hvordan daginstitutionsledere og pædagogisk personale i en række danske daginstitutioner for 0-6-årige børn løfter den store samfundsmæssige udfordring at håndtere COVID-19 pandemien på landets daginstitutioner.
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Peters, T., A. Washington, F. Fondeur, and S. Fink. SOLVENT HOLD TANK SAMPLE RESULTS FOR MCU-11-314, MCU-11-315, MCU-11-316, MCU-11-317, MCU-11-318 AND MCU-11-319. Office of Scientific and Technical Information (OSTI), June 2011. http://dx.doi.org/10.2172/1018484.

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Peters, T., F. Fondeur, and S. Fink. SOLVENT HOLD TANK SAMPLE RESULTS FOR MCU-11-1452, MCU-11-1453, MCU-11-1454, MCU-11-1455, MCU-11-1456 AND MCU-11-1457. Office of Scientific and Technical Information (OSTI), January 2012. http://dx.doi.org/10.2172/1032954.

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Peters, T., A. Washington, F. . Fondeur, and S. Fink. SUPPLEMENTAL ANALYSES FOR SOLVENT HOLD TANK SAMPLES MCU-11-314, MCU-11-315, MCU-11-316, MCU-11-317, MCU-11-318 AND MCU-11-319. Office of Scientific and Technical Information (OSTI), September 2011. http://dx.doi.org/10.2172/1026684.

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Massotti, Luca, Günther March, and Ilias Daras. Next Generation Gravity Mission as a Mass-change And Geosciences International Constellation (MAGIC) Mission Requirements Document. Edited by Roger Haagmans and Lucia Tsaoussi. European Space Agency, October 2020. http://dx.doi.org/10.5270/esa.nasa.magic-mrd.2020.

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MAGIC is the joint NASA/ESA constellation concept based on NASA’s Mass Change Designated Observable (MCDO) and ESA’s Next Generation Gravity Missions (NGGM) studies. The main objective of MAGIC is to extend the mass transport time series of previous gravity missions such as GRACE and GRACE-FO with significantly enhanced accuracy, spatial and temporal resolutions and to demonstrate the operational capabilities of MAGIC with the goal of answering global user community needs to the greatest possible extent. This document defines unambiguous and traceable requirements for preparing and developing MAGIC. The scope of the MAGIC Mission Requirement Document includes end-to-end Earth observation system including user/scientific requirements, mission operations, data product development and processing, data distribution and data archiving. The intention of the document is also to accommodate results from NASA MCDO study, ESA Phase-0 NGGM and other national studies on future gravity missions. The MAGIC MRD is a NASA/ESA reference document frozen in its current version 1.0 that defines the mission requirements achievable by an optimised two-pair Bender-type constellation of a future implementation. Subsequent ESA and NASA official documents of updated implementation baseline will be traceable to the MAGIC MRD.
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Fondeur, F. F., and K. M. Taylor-Pashow. Solvent Hold Tank Sample Results For MCU-13-814, MCU-13-815, MCU-13-816, MCU-13,817, MCU-13-818 And MCU-13-819: Quarterly Sample From May 2013. Office of Scientific and Technical Information (OSTI), August 2013. http://dx.doi.org/10.2172/1090763.

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Fondeur, F. F., T. B. Peters, and S. D. Fink. SOLVENT HOLD TANK SAMPLE RESULTS FOR MCU-12-488, MCU-12-489, MCU-12-490, MCU-12-491, MCU-12-492 AND MCU-12-493: QUARTERLY SAMPLE FROM OCTOBER 2012. Office of Scientific and Technical Information (OSTI), January 2013. http://dx.doi.org/10.2172/1061033.

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Fondeur, F. F., and T. B. Peters. Solvent hold tank sample results for MCU-13-143, MCU-13-144, MCU-13-145, MCU-13-146, MCU-13-147 AND MCU-13-148: quarterly sample from January 2013. Office of Scientific and Technical Information (OSTI), March 2013. http://dx.doi.org/10.2172/1073613.

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Nelson, Gena, Angela Crawford, and Jessica Hunt. A Systematic Review of Research Syntheses for Students with Mathematics Learning Disabilities and Difficulties. Boise State University, Albertsons Library, January 2022. http://dx.doi.org/10.18122/sped.143.boisestate.

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The purpose of this document is to provide readers with the coding protocol that authors used to code 36 research syntheses (including meta-analyses, evidence-based reviews, and quantitative systematic reviews) focused on mathematics interventions for students with learning disabilities (LD), mathematics learning disabilities (MLD), and mathematics difficulties (MD). The purpose of the systematic review of mathematics intervention syntheses was to identify patterns and gaps in content areas, instructional strategies, effect sizes, and definitions of LD, MLD, and MD. We searched the literature for research syntheses published between 2000 and 2020 and used rigorous inclusion criteria in our literature review process. We evaluated 36 syntheses that included 836 studies with 32,495 participants. We coded each synthesis for variables across seven categories including: publication codes (authors, year, journal), inclusion and exclusion criteria, content area focus, instructional strategy focus, sample size, methodological information, and results. The mean interrater reliability across all codes using this coding protocol was 90.3%. Although each synthesis stated a focus on LD, MLD, or MD, very few students with LD or MLD were included, and authors’ operational definitions of disability and risk varied. Syntheses predominantly focused on word problem solving, fractions, computer- assisted learning, and schema-based instruction. Syntheses reported wide variation in effectiveness, content areas, and instructional strategies. Finally, our results indicate the majority of syntheses report achievement outcomes, but very few syntheses report on other outcomes (e.g., social validity, strategy use). We discuss how the results of this comprehensive review can guide researchers in expanding the knowledge base on mathematics interventions. The systematic review that results from this coding process is accepted for publication and in press at Learning Disabilities Research and Practice.
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