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Enseroth, Timo [Verfasser]. "Konstruktion und Validierung der MCD-Skala zur Erfassung unterschwelliger organischer Psychosyndrome (Minimale Cerebrale Dysfunktion, MCD) im Erwachsenenalter / Timo Enseroth." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2011. http://d-nb.info/1026264200/34.
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Arvidsson, Ann-Christine. "Framtagningav miljöbedömningsmetod av leverantörer : arbetet utfört hos Parker Hannifin AB MCD." Thesis, University West, Department of Informatics and Mathematics, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-889.
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Singer, R. "Matrix induced effects in the MCD spectra of isolated metal atoms." Thesis, University of East Anglia, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374272.
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Wolff, Pamela A. Carleton University Dissertation Chemistry. "Electronic and magnetic hypersensitivity in the MCD spectra of lanthanide complexes." Ottawa, 1990.
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Irvine, Alan David. "Mutation analysis in human keratin diseases." Thesis, Queen's University Belfast, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268237.
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Hualpa, Benavente Flor Patricia. "Componentes principales mediante el método robusto MCD: Matriz de covarianzas de determinante mínimo." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2012. https://hdl.handle.net/20.500.12672/3136.
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Este trabajo de investigación aborda el problema de falta de robustez, mediante el reemplazo de la matriz de covarianzas obtenida con el método clásico, por la matriz de covarianzas obtenida con el método robusto MCD (Todorov y Filzmoser, 2009). El método robusto MCD: Minimun Covariance Determinant, consiste en realizar las estimaciones para el vector de medias y la matriz de covarianzas a partir de la selección de una submuestra obtenida del remuestreo del conjunto de datos en estudio, cuya característica principal es que tiene la matriz de covarianzas con determinante mínimo.
Muchas veces, el análisis estadístico en presencia de datos atípicos, mediante métodos clásicos, puede llevar a conclusiones erróneas debido a la sensibilidad de dichos métodos, por ello el objetivo del presente trabajo es presentar la metodología de los estimadores MCD, a fin de conseguir una “matriz de covarianzas robustificada” la cual será utilizada para realizar el Análisis de Componentes Principales en conjuntos de datos con presencia de observaciones atípicas.
Se ilustra la metodología de la teoría y la aplicación para dos conjuntos de datos, resultados de investigaciones en la Botánica (Quinteros, 2010 y Gómez, et. al., 2008), se analiza el comportamiento de las Componentes Principales con la metodología MCD y se compara con la metodología clásica. Se determina que las Componentes Principales obtenidas por el método de MCD permiten encontrar mejores indicadores para los conjuntos de datos que tienen valores atípicos.
-- Palabras clave: Minimum Covariance Determinant, MCD, Componentes Principales, Estimación Robusta, Matriz de Varianzas y Covarianzas.--- This research addresses the problem of lack of robustness, by replacing the covariance matrix obtained with the classical method for the covariance matrix obtained with the robust MCD method (Todorov and Filzmoser, 2009). The robust method MCD: Minimun Covariance Determinant, involves making estimates for the mean vector and covariance matrix from the selection of a subsample obtained from the resampling of the data set under study, whose main characteristic is that it has the covariance matrix with the minimum determinant. Many times, the statistical analysis in the presence of outliers, by standard methods, can be misleading because of the sensitivity of these methods, which is why the objective of this paper is to present the methodology of the MCD estimators in order to achieve the "robustified covariance matrix" which will be used to perform Principal Component Analysis on data sets with the presence of outliers. We illustrate the methodology of the theory and application, for two sets of data, research results in the Botany (Quinteros, 2010 and Gomez, et. Al., 2008), we analyze the behavior of the Principal Components with the MCD method and we compare it to the classic methodology. It is determined that the principal components obtained by the MCD method allows to find better indicators for data sets with outliers. -- Keywords: Minimum Covariance Determinant, MCD, Principal Components, Robust Estimation, Scatter Matrix.
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Toriguchi, Kan. "CHOP deficiency attenuates steatohepatitis, fibrosis and carcinogenesis in mice fed an MCD diet." Kyoto University, 2014. http://hdl.handle.net/2433/188659.
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Westphal, Anne [Verfasser]. "UV/Vis, MCD and EPR Spectra of Mononuclear Manganese and Molybdenum Complexes / Anne Westphal." Kiel : Universitätsbibliothek Kiel, 2014. http://d-nb.info/1053653530/34.
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Warnke, Max Holger [Verfasser]. "Klinische Korrelate von Indikatoren komplexer Teilleistungsstörungen bzw. Minimaler Cerebraler Dysfunktion (MCD) / Max Holger Warnke." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2012. http://d-nb.info/1030382522/34.
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Gonzales, de Olarte Efraín. "La Matriz de Capacidades y Desempeños (MCD) y el Algoritmo del Desarrollo Humano (ADH)." Economía, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/117871.
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Given that human development is a complex process involving multiple components and determiningfactors, multidimensional indicators are needed. On the basis of the extensive literatureon the subject, we advance two new indicators: the Matrix of Capabilities and Functioning(MCF), and the Algorithm of Human Development (HDA).The MCF is composed of vectors of capabilities and functionings, based on Sen’s idea of RefinedFunctionings. It is based in a matricial framework, both static and dynamic. The main purposeof constructing this index is to study how different sets of capabilities relate to alternativefunctionings, to produce diverse outcomes.The Human Development Algorithm (HAD) is a multidimensional index concerning the setof goods and services needed to complete a life cycle. The HDA is a socio-economic contextindicator. It is composed of the main «satisfactors» or basic goods and services needed: food,health, education, housing, social security, decent employment and retirement programs, thatmight be available to all throughout of life cycle. This indicator shows the material progressreached by each country or region as well the institutional organization, private and public, andthe degree of social cohesion and solidarity.Dado que el desarrollo humano es un proceso complejo que tiene múltiples componentes ydeterminantes, es necesario tener indicadores multidimensionales tales como la Matriz de Capacidadesy Desempeños (MCD) y el Algoritmo del Desarrollo Humano (ADH).El MCD está compuesto de vectores de capacidades y de desempeños, basado en la idea de Sensobre desempeños refinados. Está basado en un marco conceptual matricial, tanto estático comodinámico. El propósito principal de la construcción del índice es estudiar cómo diferentes conjuntosde capacidades con desempeños pueden producir distintos resultados.El ADH es un índice multidimensional relacionado con el conjunto de bienes y servicios que senecesitan para completar un ciclo de vida. El ADH es un indicador de contexto socioeconómico.Está compuesto de los principales satisfactores o bienes y servicios básicos que se requieren: alimentos,salud, educación, vivienda, seguridad social, empleo decente y sistema de pensiones, quedeben estar disponibles durante todo el ciclo de vida. Este indicador muestra el progreso materialalcanzado por cada país o región, tanto como la organización institucional pública y privada, yel grado de cohesión social.
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Karimova, Natalia Vladimirovna. "Theoretical study of the optical properties of the noble metal nanoparticles: CD and MCD spectroscopy." Diss., Kansas State University, 2017. http://hdl.handle.net/2097/38177.
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Doctor of PhilosophyDepartment of Chemistry
Christine M. Aikens
Gold and silver particles with dimensions less than a nanometer possess unique characteristics and properties that are different from the properties of the bulk. They demonstrate a non–zero HOMO–LUMO gap that can reach up to 3.0 eV. These differences arise from size quantization effects in the metal core due to the small number of atoms. These nanoparticles have attracted great interest for decades both in fundamental and applied research. Small gold clusters protected by various types of ligands are of interest because ligands allow obtaining gold nanoclusters with given sizes, shapes and properties. Three main families of organic ligands are usually used for stabilization of gold nanoclusters: phosphine ligands, thiolate ligands and DNA. Usually, optical properties of these NPs are studied using optical absorption spectroscopy. Unfortunately, sometimes this type of spectrum is poorly resolved and tends to appear very similar for different complexes. In these cases, circular dichroism (CD) and magnetic circular dichroism (MCD) spectroscopy can be applied. However, the interpretation of experimental CD and MCD spectra is a complicated process. In this thesis, theoretically simulated CD and MCD spectra were combined with optical absorption spectra to study optical activity for octa– and nona– and undecanuclear gold clusters protected by mono– and bidentate phosphine ligands. Additionally, optical properties of bare and DNA protected silver NPs were studied. Theoretical CD spectra were examined to learn more about the origin of chirality in chiral organometallic complexes, and to contribute to the understanding of the difference in chiroptical activity of gold clusters stabilized by different phosphine ligands and DNA–stabilized silver clusters. Furthermore, optical properties of the small centered gold clusters Au₈(PPh₃)₈²⁺ and Au₉(PPh₃)₈³⁺ were examined by optical absorption and MCD spectra using TDDFT. Theoretical MCD spectra were also used to identify the plasmonic behavior of silver nanoparticles. These results showed that CD and MCD spectroscopy yield more detailed information about optical properties and electronic structure of the different chemical systems than optical absorption spectroscopy alone. Theoretical simulation of the CD and MCD spectra together with optical absorption spectra can be used to assist in the understanding of empirically measured CD and MCD and provide useful information about optical properties and electronic structure.
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Bsatee, Mohammed N. "The Development of Experimental Setup for Various Magneto-Optical Studies." Ohio University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1438868631.
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Peng, Peijing. "Interaction of alpha-gamma-MSH analogues with MC1, MC3 and MC4 melanocortin receptors." Thesis, University of Bath, 1997. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338413.
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Mooranian, Mahsa. "My Crystal Diary (MCD) : an integrated software application for recording the observations and results of crystallisation experiments." University of Western Australia. School of Electrical, Electronic and Computer Engineering, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0121.
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Recent technological advances in computer science have contributed to immense data generation in many critical areas of biology. These data can be used in intelligent information systems to better understand biological processes from the atomic details of biological molecules to the interaction of species in an ecosystem. This thesis presents My Crystal Diary (MCD), an integrated software application designed for use in an intelligent decision-support system for planning novel crystallisation experiments. PostgreSQL database server is the information repository containing both the experimental data and general knowledge. Web-based interfaces developed in Plone provide remote access to the database by utilizing a Zope Web application server.
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Luna, Brenda. "Prenatal Environmental Exposure and Neurodevelopmentally Important Gene Expression in Malformed Brain Tissue from Pediatric Intractable Epilepsy Patients." FIU Digital Commons, 2011. http://digitalcommons.fiu.edu/etd/445.
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The primary objective of this proposal was to determine whether mitochondrial oxidative stress and variation in a particular mtDNA lineage contribute to the risk of developing cortical dysplasia and are potential contributing factors in epileptogenesis in children. The occurrence of epilepsy in children is highly associated with malformations of cortical development (MCD). It appears that MCD might arise from developmental errors due to environmental exposures in combination with inherited variation in response to environmental exposures and mitochondrial function. Therefore, it is postulated that variation in a particular mtDNA lineage of children contributes to the effects of mitochondrial DNA damage on MCD phenotype. Quantitative PCR and dot blot were used to examine mitochondrial oxidative damage and single nucleotide polymorphism (SNP) in the mitochondrial genome in brain tissue from 48 pediatric intractable epilepsy patients from Miami Children’s Hospital and 11 control samples from NICHD Brain and Tissue Bank for Developmental Disorders.
Epilepsy patients showed higher mtDNA copy number compared to normal health subjects (controls). Oxidative mtDNA damage was lower in non-neoplastic but higher in neoplastic epilepsy patients compared to controls. There was a trend of lower mtDNA oxidative damage in the non-neoplastic (MCD) patients compared to controls, yet, the reverse was observed in neoplastic (MCD and Non-MCD) epilepsy patients. The presence of mtDNA SNP and haplogroups did not show any statistically significant relationships with epilepsy phenotypes. However, SNPs G9804A and G9952A were found in higher frequencies in epilepsy samples. Logistic regression analysis showed no relationship between mtDNA oxidative stress, mtDNA copy number, mitochondrial haplogroups and SNP variations with epilepsy in pediatric patients. The levels of mtDNA copy number and oxidative mtDNA damage and the SNPs G9952A and T10010C predicted neoplastic epilepsy, however, this was not significant due to a small sample size of pediatric subjects. Findings of this study indicate that an increase in mtDNA content may be compensatory mechanisms for defective mitochondria in intractable epilepsy and brain tumor. Further validation of these findings related to mitochondrial genotypes and mitochondrial dysfunction in pediatric epilepsy and MCD may lay the ground for the development of new therapies and prevention strategies during embryogenesis.
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Sokolov, A. E., V. N. Zabluda, S. G. Ovchinnikov, B. A. Knyazev, V. V. Gerasimov, Yu L. Michlin, E. A. Veshnyakova, Y. V. Zubavichus, and A. M. Kalsin. "Magnetooptics in Gold and Silver NanoSizes Low-Dimensional Objects." Thesis, Sumy State University, 2013. http://essuir.sumdu.edu.ua/handle/123456789/35344.
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The spectra of optical absorption and of magnetic circular dichroism (MCD) have been measured in the 350–1150 nm wavelength range for a set of colloidal solutions containing Au and Ag nanoparticles. The average size of Au nanoparticles was 6 nm and having thiolate coatings with different degrees of chirality. (The average size of Ag nanoparticles was 14 nm and having citrate coatings) The form of absorption and MCD spectra suggests the dipole character of interband transitions involving the 5d–6(sp) for Au orbitals and 4d–5(sp) for Ag orbitals. The absence (within the experimental error) of the MCD spectra dependence on the coating type rules out the hypothesis on the orbital nature of the observed magnetism. We argue that the spin polarization plays the dominant role in the magnetism both for Au and Ag nanoparticles.
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Assunção, Gabriel de Oliveira. "Conversor CA-CC trifásico de estágio único com elevado fator de potência baseado no conversor SEPIC MCD com interruptores bidirecionais." Universidade Tecnológica Federal do Paraná, 2016. http://repositorio.utfpr.edu.br/jspui/handle/1/2409.
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Este trabalho apresenta uma nova topologia de conversor CA-CC trifásico de estágio único com elevado fator de potência baseado no conversor SEPIC MCD, contendo interruptores bidirecionais. Este se comporta como um seguidor da tensão mesmo em malha aberta (característica dos conversores SEPIC MCD), ou seja, emula uma resistência do ponto de vista da rede elétrica. Sendo assim, o esforço de controle é reduzido a apenas uma malha de controle, sendo esta para controlar a tensão de saída, como em um conversor CC-CC. Este conversor de estágio único tem elevada confiabilidade, uma vez que emprega quatro interruptores ativos, com o mesmo sinal de comando, e seis diodos de alta frequência para a conversão de corrente alternada para corrente contínua (CA-CC) com alto fator de potência e isolação em alta frequência. Como desvantagens, tem-se a restrição na escolha da relação de transformação, a qual implica em elevados valores de corrente no secundário para baixas tensões de saída. São apresentadas as etapas de operação, as formas de onda ideais, as equações que regem o funcionamento do conversor, os resultados de simulação numérica contrastados com os valores teóricos e resultados experimentais. As especificações aplicadas ao conversor são 127 V na tensão de entrada, 200 V na tensão de saída, 50 kHz da frequência de comutação e 1500 W de potência para a carga. O protótipo gerado a partir dessas especificações apresenta 0,9981 de fator de potência, 4,234% de taxa de distorção harmônica e um rendimento de 85,522% para condições nominais. Devido as suas características, considera-se uma boa opção para sistemas trifásicos de baixa potência, onde não se justifica um elevado custo.This work presents a new three-phase high power factor single-stage AC-DC converter based on the DCM SEPIC topology, using bidirectional switches. This converter operates as a voltage follower even in open loop (SEPIC DCM converter characteristic), in other words, it emulates a resistance from the electric grid point of view. Therefore, the control effort is reduced to a single control loop to control the DC output voltage, like an output voltage control of a DC-DC converter. This single-stage converter has high reliability, since it employs four active switches with the same command signal and six high frequency diodes for AC-DC conversion with high power factor and high frequency isolation. A system disadvantage is related to the constraint in the choice of transformer turns, which leads to high current values in the secondary-side for lower output voltage specifications. Hereon are presented the operation modes, the ideal waveforms, the main equations of the converter, the numerical simulation results contrasting with the theoretical values and experimental results. Design specifications are 127 V input voltage, 200 V output voltage, 50 kHz switching frequency and 1500 W output power. The prototype is obtained by following the specifications and it shows 0.9981 of power factor, 4.234% of total harmonic distortion and 85.522% of efficiency for rated condition. This converter is considered a choice for low power three-phase systems with low cost realization.
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Paulat, Florian [Verfasser]. "Synthesis, MCD- and Raman-spectroscopic, and quantum chemical investigation of ferric heme model complexes and their reaction with NO / Florian Paulat." Kiel : Universitätsbibliothek Kiel, 2010. http://d-nb.info/1019952024/34.
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Daffé, Niéli. "Anisotropies and Magnetic Couplings of Texturable Ferrofluids." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066640/document.
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Les ferrofluides sont des suspensions colloïdales de nanoparticules magnétiques dispersées dans un liquide porteur. La possibilité de moduler les propriétés des ferrofluides in situ en appliquant un champ magnétique externe leur procure un fort potentiel d’étude, à la fois d’un point de vue fondamental ou pour des applications industrielles variées. En particulier, les nanospinels de ferrite ferrimagnétiques MFe2O4 (M = Fe2+, Co2+, Mn2+…) sont largement étudiés pour leurs propriétés électriques et magnétiques. Plus spécifiquement, une forte énergie d’anisotropie de ces matériaux à l’échelle nanométrique est requise pour des applications dans le stockage de l’information ou l’hyperthermie pour lesquels ils sont considérés. Une connaissance fine des mécanismes régissant ces propriétés d’anisotropies magnétiques est ainsi primordiale pour la création de nouveaux objets aux propriétés magnétiques contrôlées à l’échelle nanométrique. L’originalité de notre approche consiste à utiliser une technique fine du magnétisme, le dichroïsme magnétique circulaire des rayons X (XMCD) à l’étude des anisotropies et couplages magnétiques des nanospinels composants les ferrofluides. Au cours de cette thèse, nous nous sommes intéressés à différentes stratégies possibles pour induire une forte énergie d’anisotropie aux nanospinels de ferrite par l’utilisation de cobalt. Des nanoparticules de tailles et compositions variées ont été obtenues par différentes voies de synthèse, et nous démontrons que l’anisotropie magnétique de ces systèmes est fortement gouvernée par la symétrie de site du Co2+ en structure spinel qui peut être directement corrélé au processus de synthèse utilisé. Nous nous sommes aussi intéressés à l’ordre et au couplage magnétique de ferrite spinels structurés en coeur-coquille, dont le cœur et la coquille sont réalisés à partir de matériaux aux propriétés magnétiques intrinsèques différentes. Nous montrons ainsi que pour des nanospinels MnFe2O4@CoFe2O4, la très fine coquille formée de CoFe2O4 impose une forte anisotropie magnétique au cœur doux de MnFe2O4. Enfin, nous nous sommes intéressés à une troisième classe de ferrofluide à base de nanospinels, les ferrofluides binaires, constitué d’un mélange physique de ferrofluides aux propriétés magnétiques intrinsèques différentes. Pour de tels systèmes, il est essentiel de préserver le liquide porteur du ferrofluide pour ne pas dénaturer les interactions entre particules existantes. L’un des objectifs de cette thèse fut donc d’étendre la technique du XMCD à l’étude d’échantillons de ferrofluides in situ, dans leur phase liquide ou gelée. Nous avons débuté la conception d’une cellule liquide compatible avec les rayons X mous et un environnement ultra-vide sur la ligne de lumière DEIMOS (SOLEIL) qui est toujours en développementFerrofluids are colloidal suspensions of magnetic nanoparticles dispersed in a carrier liquid. The intimate interaction between the magnetic nanoparticles and the liquid provides a unique system, from both fundamental and industrial application point of views, whose flow and properties can be precisely controlled using an external magnetic field. Magnetic nanoparticles of spinel ferrites MFe2O4 (M = Fe2+, Co2+, Mn2+…) are of particular scientific interest and have been extensively studied for their electrical and magnetic properties. Spinel ferrites find potential applications, notably in storage devices, for computers, or hyperthermia, for cancer treatment, where high magnetic anisotropy energies are required at the nanoscale. However, deeper knowledges of the fine mechanisms playing a significant role on the magnetic anisotropies existing in the nanospinels are necessary to help the creation of rationalized materials with controlled magnetic anisotropies for the requirement of the system. In this thesis, we have used X-ray Magnetic Circular Dichroism (XMCD) as an original approach for probing the magnetic anisotropies and magnetic couplings of nanospinels obtained in ferrofluids. The nanoparticles are iron bearing spinels for which cobalt ions have been introduced in the spinel structure of the nanoparticles as a true makers of magnetic anisotropy. First, magnetic nanospinels have been synthesized by tuning their size and composition and using different synthesis processes. XMCD investigations revealed that the coercive field of the nanospinels is governed by the concentration of Co2+ ions sitting in octahedral sites of the spinel structure, and this can be directly linked to some synthesis parameters. Then, we have investigated core@shell nanoparticles, which can be synthesized with an appropriate choice of magnetic anisotropies for the core and the shell in order to tailor optimal magnetic properties. In the case of MnFe2O4@CoFe2O4, our findings reveal that the very thin CoFe2O4 shell imposes a strong magnetic anisotropy to the otherwise very soft MnFe2O4 core. The other class of ferrofluids that has been investigated during this thesis are binary ferrofluids that are constituted of two different types of magnetic nanoparticles. For such systems, the carrier liquid must be preserved to understand the magnetic interactions in the ferrofluid as they are. Another motivation of this thesis was thus to extend XMCD to the in situ investigation of the nanospinels dispersed in ferrofluids. We have been started a liquid cell development in the DEIMOS beamline at SOLEIL. The setup is still in progress and is aimed at being compatible with soft X-Rays short penetration depth and ultra-high vacuum environment. Hard X-ray photon-in/photon-out spectroscopy coupled to XMCD (1s2p RIXS-MCD) can be a very valuable alternative to soft X-ray XMCD at K-edge of 3d elements when liquid cell sample environment is required. The instrumental development of a liquid cell used with 1s2p RIXS-MCD spectroscopy allowed us to investigate the nanoparticles directly in the ferrofluids revealing interparticles magnetic couplings in binary ferrofluids
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Viero, Renan Caron. "Estudo da modelagem dinâmica de pequenos sinais do conversor ZETA no MCD alimentado a partir de painéis fotovoltaicos para conexão à rede elétrica." Pontifícia Universidade Católica do Rio Grande do Sul, 2011. http://hdl.handle.net/10923/3138.
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Previous issue date: 2011This work presents the study and development of the small-signal dynamic modeling of the ZETA converter operating in discontinuous conduction mode, powered from photovoltaic solar panels in order to connect them to the power grid. Initially, it is presented a study of the main characteristics of solar cells. A deep analysis of the ZETA converter working in steady state is performed, considering that the Zeta converter synthesizes a rectified sine wave current with the same frequency as the power grid. This feature makes this converter a key part in implementing the module integrated inverter for photovoltaic systems. The converter is analyzed in the switching frequency and in the power grid frequency. A detailed examination of the dynamic behavior of the Zeta converter is achieved by the state-space averaging modeling approach, resulting in a linear analytical model described in state variables. In all tests it was assumed that the commercial power grid presents a resistive load behavior (variable value). Finally, the analytical dynamic model obtained is validated through computer simulations and by laboratory tests on a prototype specially designed for this purpose.
Este trabalho apresenta o estudo e o desenvolvimento da modelagem dinâmica de pequenos do conversor ZETA operando no modo de condução descontínuo, alimentado a partir de painéis solares fotovoltaicos, para conexão à rede elétrica. Inicialmente, é apresentado um estudo das principais características das células solares. Uma análise profunda sobre o conversor ZETA operando em regime permanente é realizada, considerando que o mesmo sintetiza uma onda senoidal retificada de baixa freqüência. O conversor é analisado tanto na freqüência de comutação como na freqüência da rede elétrica. Esta característica transforma este conversor em uma peça fundamental na implementação do inversor módulo integrado para sistemas fotovoltaicos. Um exame detalhado do comportamento dinâmico do conversor é realizado através da abordagem do modelo médio no espaço de estados, resultando em um modelo linear analítico descrito em variáveis de estado. Em todas as análises se assume a rede elétrica comercial como uma carga com comportamento resistivo (variável). Por fim, o modelo dinâmico analítico obtido é validado através de simulações computacionais e através de ensaios laboratoriais em um protótipo especialmente elaborado para este fim.
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Levada, Kateryna [Verfasser], Andreas Akademischer Betreuer] Ludwig, Pavel [Akademischer Betreuer] Strnad, and Gabriele [Akademischer Betreuer] [Pradel. "Hsp72 overexpression protects from APAP and MCD induced liver injury via attenuation of JNK signalling / Kateryna Levada ; Andreas Ludwig, Pavel Strnad, Gabriele Pradel." Aachen : Universitätsbibliothek der RWTH Aachen, 2016. http://d-nb.info/1129876152/34.
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Mourre, Christiane. "Localisation de canaux ioniques dans le système nerveux central de mammifère." Nice, 1987. http://www.theses.fr/1987NICE4127.
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Viero, Renan Caron. "Estudo da modelagem din?mica de pequenos sinais do conversor ZETA no MCD alimentado a partir de pain?is fotovoltaicos para conex?o ? rede el?trica." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2011. http://tede2.pucrs.br/tede2/handle/tede/3039.
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Previous issue date: 2011-09-08Este trabalho apresenta o estudo e o desenvolvimento da modelagem din?mica de pequenos do conversor ZETA operando no modo de condu??o descont?nuo, alimentado a partir de pain?is solares fotovoltaicos, para conex?o ? rede el?trica. Inicialmente, ? apresentado um estudo das principais caracter?sticas das c?lulas solares. Uma an?lise profunda sobre o conversor ZETA operando em regime permanente ? realizada, considerando que o mesmo sintetiza uma onda senoidal retificada de baixa freq??ncia. O conversor ? analisado tanto na freq??ncia de comuta??o como na freq??ncia da rede el?trica. Esta caracter?stica transforma este conversor em uma pe?a fundamental na implementa??o do inversor m?dulo integrado para sistemas fotovoltaicos. Um exame detalhado do comportamento din?mico do conversor ? realizado atrav?s da abordagem do modelo m?dio no espa?o de estados, resultando em um modelo linear anal?tico descrito em vari?veis de estado. Em todas as an?lises se assume a rede el?trica comercial como uma carga com comportamento resistivo (vari?vel). Por fim, o modelo din?mico anal?tico obtido ? validado atrav?s de simula??es computacionais e atrav?s de ensaios laboratoriais em um prot?tipo especialmente elaborado para este fim
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Levin, Gustavo Hoppe. "Estudo e desenvolvimento de controladores ressonantes para um inversor módulo-integrado baseado no Conversor Zeta no MCD para a conexão de painéis PV à rede elétrica." Pontifícia Universidade Católica do Rio Grande do Sul, 2013. http://hdl.handle.net/10923/5595.
Full textAbstract:
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Previous issue date: 2013This work proposes the study and implementation of resonant controllers applied to photovoltaic panels grid-tied by a Zeta converter. This converter is designed to synthesize a rectified sinusoidal waveform current with low-harmonic content. Operating in discontinuous conduction mode, the Zeta Converter is connected to a full-bridge inverter so that one semi-cycle of the output current is inverted for every cycle of the power grid voltage, allowing the connection of PV panels to the power grid. The assembly formed by PV panel and inverter is known as Module-Integrated Inverter (MII). By aiming the project of resonant controllers, an analysis of the Zeta converter is presented, including its state-space model proposed in previous works. Furthermore, fundamental robust control concepts involved on the resonant controllers project are presented. In order to determine the gains of the resonant controllers, a formulation based on Linear Matrix Inequalities (LMIs) that guarantees the stability and performance of the closed-loop system is presented. A state-observer is also designed, reducing the number of variables that must be measured. Finally, the developed control strategy is validated through computational simulations and laboratorial tests on a prototype specially developed to this purpose. The results obtained by the experimental results validated the purpose, confirming the viability of using resonant controllers for this application, in order to synthesize a sinusoidal current waveform with low-harmonic content, synchronized with the power grid.
Este trabalho propõe o estudo e a aplicação de controladores ressonantes desenvolvidos para um Conversor Zeta, o qual foi concebido para sintetizar à sua saída uma forma de onda de corrente senoidal retificada, com baixo conteúdo harmônico, visando desta forma o aproveitamento da energia gerada a partir de painéis solares fotovoltaicos (PV). Operando no modo de condução descontínuo, o conversor Zeta é conectado em cascata a um inversor em ponte completa, visando inverter um dos semiciclos da sua corrente de saída a cada ciclo da tensão da rede, permitindo assim a conexão dos painéis PV à rede elétrica da concessionária de energia. O conjunto formado por painel PV e inversor é conhecido como Inversor Módulo-Integrado. Visando o projeto dos controladores ressonantes, apresenta-se uma análise do Conversor Zeta, incluindo o modelo de espaço de estados proposto em trabalhos anteriores. Em seguida, apresentam-se conceitos fundamentais de controle robusto envolvidos no projeto dos controladores ressonantes. Para determinação dos ganhos dos controladores ressonantes, apresenta-se uma formulação baseada em desigualdades matriciais lineares (LMIs). Um observador de estados também é projetado, visando diminuir o número de variáveis a serem medidas. Logo depois, a metodologia de controle é apresentada, acompanhada do projeto do observador de estados. Por fim, a estratégia de controle desenvolvida é validada através de simulações computacionais e através de ensaios laboratoriais em um protótipo especialmente elaborado para este fim. Os resultados obtidos experimentalmente validaram a proposta, resultando na síntese de uma forma de onda senoidal de corrente, com baixo conteúdo harmônico, sincronizada com a rede elétrica da concessionária.
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Li, Donghui. "MCG: A multilayer general area MCM routing algorithm." Diss., The University of Arizona, 1995. http://hdl.handle.net/10150/187524.
Full textAbstract:
A new multilayer, general-area, multichip module (MCM) routing algorithm, called MCG, is introduced. The algorithm differs from other MCM routers in the way that the routes interconnecting the nets are constructed. Some routers perform the routing net-by-net and others extend the routes piece by piece during the routing process. The MCG router takes a more global approach by constructing a small number of candidate routes for each net, building a compatibility graph for the candidate routes and reducing the graph to yield a routing solution. Due to this unique way of performing the routing, the MCG router offers several outstanding features. First, it performs the routing of the nets simultaneously. Therefore it is not subject to the net ordering problem. Second, it can give the designer the flexibility of selecting the topology of routes for the nets to be routed, which is almost impossible for other algorithms. Third, it offers a natural way to incorporate the electrical constraints into the routing process, which is absent or hard to handle in other algorithms. The timing constraint can be incorporated easily by constructing the candidate routes of the net according to the requirements of the design; and the compatibility test of the candidate routes can be used to estimate the crosstalk between the routes from different nets, which make the crosstalk estimation more sophisticated than the other techniques. Compared with other MCM routers, the MCG router produces better quality routing solutions in terms of number of layers, number of vias, total wire length and routing density. In addition to the application in the area of MCM routing, the MCG algorithm can also be applied to high density PCB routing problems.
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Ligorio, Danilo. "Virtual commissioning di una macchina automatica per la messa in passo di prodotti." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017.
Find full textAbstract:
L’obiettivo di questo elaborato di tesi è quello di testare ed analizzare le tecnologie del virtual commissioning messe a disposizione da Siemens, applicate a un caso reale. Il caso di studio preso in esame riguarda una macchina industriale di proprietà della Sitma Machinery S.p.A. per il confezionamento di generi alimentari. Nello specifico il virtual commissioning verrà applicato al modulo di macchina atto alla messa in passo dei prodotti tramite nastri trasportatori.
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Schneider, Martin. "Návrh spektrometru s opticky detekovanou magnetickou rezonancí." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2017. http://www.nusl.cz/ntk/nusl-318818.
Full textAbstract:
Diplomová práce se zabývá návrhem a sestavením nového spektrometru opticky detekované magnetické rezonance (ODMR) modifikací stávajícího spektrometru magnetického kruhového dichroismu (MCD) přivedením mikrovlnného ozařování. Je navrhnut nový držák vzorku umožnující osvětlení jak viditelným světlem, tak mikrovlnným zářením. Pro přivedení vlnění o nižších frekvencích je navržena anténa, určená k umístění pod vzorkem. Schopnosti celého systému jsou demonstrovány na sloučenínách kovových komplexů.
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KOUSSIH, LATIFA. "Contribution a l'etude de la matiere organique dissoute (mcd) excretee par deux diatomees marines, skeletonema costatum (grev. ) cleve et haslea ostrearia simonsen : role dans la complexation des metaux." Nantes, 1995. http://www.theses.fr/1995NANT2040.
Full textAbstract:
Dans cette etude il est montre que la matiere organique dissoute (mod) presente dans les cultures de deux diatomees marines skeletonema costatum et haslea ostrearia, ne provient pas principalement de la lyse des cellules ni de la dissolution de la paroi mais bien d'une excretion par les cellules saines. Les suivis realises dans les differentes cultures montrent que les aald et les sucres sont excretes pendant la phase exponentielle de croissance. Les acides amines majoritaires (asp, glu, ser, gly/thr, ala/tyr) rencontres sont ceux habituellement trouves dans l'eau de mer, mais a des concentrations beaucoup plus elevees. En outre, le sucre majoritaire est le glucose, en particulier dans les cultures de s. Costatum. Le suivi d'un bloom automnal de s. Costatum en conditions naturelles montre a la difference des cultures in vitro, que seul l'acide glutamique est accumule au cours de la croissance et qu'une liberation importante de la mod a lieu entre 16 h et 20 h. Le role de la mod dans la complexation des metaux (cu#2#+ en particulier) est mis en evidence par l'utilisation de deux methodes: l'une biologique et l'autre electrochimique (anodic strepping voltametry: asv). La premiere atteste que pour h. Ostrearia la toxicite du metal est reduite en presence de la mod provenant des excretats de s. Costatum, reduction proportionnelle a la quantite de mod presente dans le milieu. Par contre, pour s. Costatum, l'augmentation de la toxicite suppose l'existence d'un ligand lipophile ayant une grande affinite pour le cuivre. Dans l'exemple d'eaux souterraines salees, les hydroxydes de fer presents dans ces eaux diminuent la toxicite du cuivre et modifient la speciation du zinc probablement par la formation de precipites metalliques mixtes. La methode electrochimique montre que ces memes eaux ultrafiltrees (500d) perdent leur capacite complexante, laissant supposer que les molecules responsables de cette complexation presentent une taille superieure a 500d
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Levin, Gustavo Hoppe. "Estudo e desenvolvimento de controladores ressonantes para um inversor m?dulo-integrado baseado no Conversor Zeta no MCD para a conex?o de pain?is PV ? rede el?trica." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2013. http://tede2.pucrs.br/tede2/handle/tede/3056.
Full textAbstract:
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Previous issue date: 2013-08-31This work proposes the study and implementation of resonant controllers applied to photovoltaic panels grid-tied by a Zeta converter. This converter is designed to synthesize a rectified sinusoidal waveform current with low-harmonic content. Operating in discontinuous conduction mode, the Zeta Converter is connected to a full-bridge inverter so that one semi-cycle of the output current is inverted for every cycle of the power grid voltage, allowing the connection of PV panels to the power grid. The assembly formed by PV panel and inverter is known as Module-Integrated Inverter (MII). By aiming the project of resonant controllers, an analysis of the Zeta converter is presented, including its state-space model proposed in previous works. Furthermore, fundamental robust control concepts involved on the resonant controllers project are presented. In order to determine the gains of the resonant controllers, a formulation based on Linear Matrix Inequalities (LMIs) that guarantees the stability and performance of the closed-loop system is presented. A state-observer is also designed, reducing the number of variables that must be measured. Finally, the developed control strategy is validated through computational simulations and laboratorial tests on a prototype specially developed to this purpose. The results obtained by the experimental results validated the purpose, confirming the viability of using resonant controllers for this application, in order to synthesize a sinusoidal current waveform with low-harmonic content, synchronized with the power grid.
Este trabalho prop?e o estudo e a aplica??o de controladores ressonantes desenvolvidos para um Conversor Zeta, o qual foi concebido para sintetizar ? sua sa?da uma forma de onda de corrente senoidal retificada, com baixo conte?do harm?nico, visando desta forma o aproveitamento da energia gerada a partir de pain?is solares fotovoltaicos (PV). Operando no modo de condu??o descont?nuo, o conversor Zeta ? conectado em cascata a um inversor em ponte completa, visando inverter um dos semiciclos da sua corrente de sa?da a cada ciclo da tens?o da rede, permitindo assim a conex?o dos pain?is PV ? rede el?trica da concession?ria de energia. O conjunto formado por painel PV e inversor ? conhecido como Inversor M?dulo-Integrado. Visando o projeto dos controladores ressonantes, apresenta-se uma an?lise do Conversor Zeta, incluindo o modelo de espa?o de estados proposto em trabalhos anteriores. Em seguida, apresentam-se conceitos fundamentais de controle robusto envolvidos no projeto dos controladores ressonantes. Para determina??o dos ganhos dos controladores ressonantes, apresenta-se uma formula??o baseada em desigualdades matriciais lineares (LMIs). Um observador de estados tamb?m ? projetado, visando diminuir o n?mero de vari?veis a serem medidas. Logo depois, a metodologia de controle ? apresentada, acompanhada do projeto do observador de estados. Por fim, a estrat?gia de controle desenvolvida ? validada atrav?s de simula??es computacionais e atrav?s de ensaios laboratoriais em um prot?tipo especialmente elaborado para este fim. Os resultados obtidos experimentalmente validaram a proposta, resultando na s?ntese de uma forma de onda senoidal de corrente, com baixo conte?do harm?nico, sincronizada com a rede el?trica da concession?ria.
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Ballerini, Simone. "Virtual commissioning of an automatic boxing machine for hardware-in-the-loop control logic validation." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018.
Find full textAbstract:
Today the increase in complexity within the development process of automatic machines and automated systems and delivery times of the control project and the various mechanical movements. This is done by creating a virtual replica of the entire machine or only by the critical parts of the same through a physical simulation software.
The objective of this thesis project is the design using a virtual commissioning software useful for testing the control logic, creating a virtual 3D model of a machine and connecting a real PLC to it.
Corazza S.p.a. world leader in the construction of machines for soup cubes, melted cheeses and butter, which for the project it has provided the CAD design of the machine and the instrumentation as PC and motion controller.
The software on which the 3D model was virtualized was delivered by Siemens and its name is NX-MCD, which provided support in the first phase of the virtual modeling.
The project was divided into two parts:
The generation of the stand-alone virtual model from the 3D CAD design.
Hardware-in-the-loop connection with Schneider PLC to move the virtual model and test the control logic.
Below there is a brief introduction to the chapters of the thesis:
The first chapter presents the meaning of virtual commissioning, considering the various technologies used and what is the goal of this type of activity.
In the second chapter there is an explanation of the software used to perform the thesis activity, studying its potential and its functionality. In he last part of the chapter there is a brief introduction of the competitors on the market.
The third chapter presents the automatic boxing machine on which the project of virtual commissioning is done, studying the task of the machine and the critic part.
In the fourth chapter explain how the virtual machine was connected to the real PLC.
In the fifth chapter we describe the pros and cons that were found during this project on virtual commissioning.
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Viding, Bussell Eva. "”Om en tjej inte skrattar åt en man får hon höra att hon inte har humor, om en kille inte skrattar åt en tjej beror det på att hon inte är rolig.” : Kategorisering av kvinnliga standupkomiker i media under två decennier." Thesis, Uppsala universitet, Institutionen för nordiska språk, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-433312.
Full textAbstract:
Kategorisering är något som görs av alla människor, hela tiden. Det är ett sätt att sortera omvärlden i olika fack och organisera strukturer för hur allting hänger ihop. Genom att analysera hur kategoriseringar skapas kan man ofta belysa underliggande normföreställningar, liksom identifiera strukturer i samhället som skulle behöva förändras. Jag ville undersöka om, och i så fall hur, media med hjälp av kategorisering befäster eller motsäger de kulturella normer som är förknippade med våra traditionella könsroller, när de rapporterar om standup och i synnerhet kvinnliga standupkomiker. I min studie har jag därför valt att analysera ett antal tidningsartiklar som handlar om kvinnliga ståuppkomiker år 2000-2019, för att granska hur dessa kvinnor porträtteras i media och om det förändras över tid. Analysen baserades på metoderna Membership Categorization Devices samt multimodal bildanalys, där jag har undersökt dels kategoriseringar och hur de skapas, dels tillhörande bildmaterial för att se om det förstärker eller motsäger budskapet i texten. Resultatet visar att kategoriseringar är vanligt förekommande i artiklarna och främst kan kopplas till de övergripande samlingskategorierna underhållning, kön, religion, kroppsuppfattning samt könsnormer. Det är en tydlig skillnad i hur mycket utrymme komikerna får att själv yttra sig i de tidigare intervjuerna jämfört med de senare, och på vilket sätt kategoriseringarna tar plats i texten. Studien visar också att intervjupersonerna ofta kategoriserar sig själva utifrån de frågor de får av intervjuaren, medan intervjuarens kategoriseringar formuleras i referat eller påståenden om personen. Bildanalysen visar inget enhetligt resultat, då samspelet mellan text och bild varierar.
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Li, Juan. "Application-Directed DVFS using Multiple Clock Domains on Graphics Hardware." Digital WPI, 2009. https://digitalcommons.wpi.edu/etd-theses/85.
Full textAbstract:
As handheld devices have become increasingly popular, powerful programmable graphics hardware for mobile and handheld devices has been deployed. While many resources on mobile devices are limited, the predominant problem for mobile devices is their limited battery power. Several techniques have been proposed to increase the energy efficiency of mobile applications and improve battery life. In this thesis, we propose a new dynamic voltage and frequency scaling (DVFS) on Graphics Processing Units (GPU). In most cases, cues within the graphics appli- cation can be used to predict portions of a GPU that will be used or unused when the application is run. We partition the GPU into six clock domains that can be clocked at different rates. Specifically, each domain it has its own voltage and frequency set- ting based on its predicted workload to save energy without reducing applications frame rates. In addition, we propose an signature-based algorithm for predicting the workload offered to our six clock domains by a given application to decide voltage and frequency settings. We conduct experiments and compare the results of our new signature based workload prediction algorithm with some other traditional interval based workload prediction algorithms. Our results show that our signature-based prediction can save 30-50% energy without afecting application frame rates.
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Liakos, Panagiotis. "Expression des récepteurs mélanocortines MC5 et MC2 dans le cortex surrénal." Université Joseph Fourier (Grenoble), 1999. http://www.theses.fr/1999GRE10100.
Full textAbstract:
Recemment le clonage de la famille des recepteurs melanocortine (mc-r) a mis en evidence cinq recepteurs melanocortines distincts couples aux proteines g et a l'adenylate cyclase. Le recepteur mc2 correspond au recepteur acth du cortex surrenal et lie uniquement l'acth. Le recepteur mc5 (mc5-r) presente une expression large, il est detecte egalement dans le cortex surrenal, et lie l'acth et l'a-msh. Au cours de ce travail, l'expression du mc5-r et du mc2-r dans les differentes zones du cortex surrenal bovin a ete etudiee. Le mc5-r est detecte uniquement dans la zone glomerulee bovine. Le mc2-r est observe dans les deux zones et ses arnm sont plus abondants dans la zone glomerulee. L'analyse de l'expression du mc5-r montre que l'acth, l'a-msh et l'all stimulent les arnm du mc5-r dans les cellules glomerulees et les arnm du mc5-r sont alors detectes dans les cellules fasciculees. Tgfb1 bloque l'expression des arnm du mc5-r induite par l'acth dans les cellules glomerulees. Le role du mc5-r dans le cortex surrenal n'est pas connu. Une premiere approche suggere que le mc5-r pourrait participer a la production d'aldosterone des cellules glomerulees. Chez le rat nouveau-ne, son expression suggere un role potentiel dans les temps precoces du developpement postnatal de la glande. Nous observons egalement une surexpression des arnm du mc5-r dans les cas d'aldosteronomes de la surrenale laissant envisager sa participation dans ces tumeurs de la surrenale comme le mc2-r.
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Robson, Geoffrey. "Multiple outlier detection and cluster analysis of multivariate normal data." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/53508.
Full textAbstract:
Thesis (MscEng)--Stellenbosch University, 2003.ENGLISH ABSTRACT: Outliers may be defined as observations that are sufficiently aberrant to arouse the suspicion of the analyst as to their origin. They could be the result of human error, in which case they should be corrected, but they may also be an interesting exception, and this would deserve further investigation. Identification of outliers typically consists of an informal inspection of a plot of the data, but this is unreliable for dimensions greater than two. A formal procedure for detecting outliers allows for consistency when classifying observations. It also enables one to automate the detection of outliers by using computers. The special case of univariate data is treated separately to introduce essential concepts, and also because it may well be of interest in its own right. We then consider techniques used for detecting multiple outliers in a multivariate normal sample, and go on to explain how these may be generalized to include cluster analysis. Multivariate outlier detection is based on the Minimum Covariance Determinant (MCD) subset, and is therefore treated in detail. Exact bivariate algorithms were refined and implemented, and the solutions were used to establish the performance of the commonly used heuristic, Fast–MCD.
AFRIKAANSE OPSOMMING: Uitskieters word gedefinieer as waarnemings wat tot s´o ’n mate afwyk van die verwagte gedrag dat die analis wantrouig is oor die oorsprong daarvan. Hierdie waarnemings mag die resultaat wees van menslike foute, in welke geval dit reggestel moet word. Dit mag egter ook ’n interressante verskynsel wees wat verdere ondersoek benodig. Die identifikasie van uitskieters word tipies informeel deur inspeksie vanaf ’n grafiese voorstelling van die data uitgevoer, maar hierdie benadering is onbetroubaar vir dimensies groter as twee. ’n Formele prosedure vir die bepaling van uitskieters sal meer konsekwente klassifisering van steekproefdata tot gevolg hˆe. Dit gee ook geleentheid vir effektiewe rekenaar implementering van die tegnieke. Aanvanklik word die spesiale geval van eenveranderlike data behandel om noodsaaklike begrippe bekend te stel, maar ook aangesien dit in eie reg ’n area van groot belang is. Verder word tegnieke vir die identifikasie van verskeie uitskieters in meerveranderlike, normaal verspreide data beskou. Daar word ook ondersoek hoe hierdie idees veralgemeen kan word om tros analise in te sluit. Die sogenaamde Minimum Covariance Determinant (MCD) subversameling is fundamenteel vir die identifikasie van meerveranderlike uitskieters, en word daarom in detail ondersoek. Deterministiese tweeveranderlike algoritmes is verfyn en ge¨ımplementeer, en gebruik om die effektiwiteit van die algemeen gebruikte heuristiese algoritme, Fast–MCD, te ondersoek.
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Reynoso, Meza Gilberto. "Controller Tuning by Means of Evolutionary Multiobjective Optimization: a Holistic Multiobjective Optimization Design Procedure." Doctoral thesis, Editorial Universitat Politècnica de València, 2014. http://hdl.handle.net/10251/38248.
Full textAbstract:
This thesis is devoted toMultiobjective Optimization Design (MOOD) procedures
for controller tuning applications, by means of EvolutionaryMultiobjective
Optimization (EMO).With such purpose, developments on tools, procedures
and guidelines to facilitate this process have been realized.
This thesis is divided in four parts. The first part, namely Fundamentals,
is devoted on the one hand, to cover the theorical background required for
this Thesis; on the other hand, it provides a state of the art review on current
applications of MOOD for controller tuning.
The second part, Preliminary contributions on controller tuning, states early
contributions using the MOOD procedure for controller tuning, identifying
gaps on methodologies and tools used in this procedure. The contribution
within this part is to identify the gaps between the three fundamental steps of
theMOOD procedure: problemdefinition, search and decisionmaking. These
gaps are the basis for the developments presented in parts III and IV.
The third part, Contributions on MOOD tools, is devoted to improve the
tools used in Part II. Although applications on the scope of this thesis are related
to controller tuning, such improvements can also be used in other engineering
fields. The first contribution regards the decision making process,
where tools and guidelines for design concepts comparison in m-dimensional
Pareto fronts are stated. The second contribution focuses on amending the gap
between search process and decisionmaking. With this in mind, a mechanism
for preference inclusion within the evolutionary process is developed. With
this it is possible to calculate pertinent approximations of the Pareto front;
furthermore, it allows to deal efficiently with many-objective and constrained
optimization instances.
Finally, in the fourth part, Final contributions on controller tuning, a stochastic
sampling procedure for proportional-integral-derivative (PID) controllers
is proposed, to guarantee that (1) any sampled controller will stabilize the
closed loop and (2) any stabilizing controller could be sampled. Afterwards,
two control engineering benchmarks are solved using this sampling strategy,
the MOOD guidelines highlighted trough this Thesis for multivariable controller
tuning and the tools developed in Part III.Reynoso Meza, G. (2014). Controller Tuning by Means of Evolutionary Multiobjective Optimization: a Holistic Multiobjective Optimization Design Procedure [Tesis doctoral]. Editorial Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/38248
Alfresco
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Gayon, Jean-Philippe. "Commande optimale de systèmes de production par anticipation." Châtenay-Malabry, Ecole centrale de Paris, 2004. http://www.theses.fr/2004ECAP0957.
Full textAbstract:
Les technologies de l'information offrent aux entreprises des possibilités croissantes pour piloter en temps réel leurs systèmes de production. Pour prendre ses décisions, le gestionnaire peut disposer d'informations telles que les niveaux des stocks, l'état de la production ou encore une information avancée sur la demande. Bien que les bénéfices liés à l'utilisation de ces informations soient intuitivement clairs, il est beaucoup moins évident de les utiliser concrètement pour prendre des décisions. Il existe un besoin réel de principes théoriques permettant d'assister les entreprises dans la définition de règles de gestion. Notre objectif est de contribuer à la définition de règles pour piloter en temps réel des systèmes de production par anticipation. Le chapitre 1 délimite le cadre de nos recherches. Le chapitre 2 présente un état de l'art et une classification des modèles de commande optimale de systèmes de production par anticipation à événements discrets stochastiques. Les chapitres 3, 4 et 5 étudient trois modèles originaux, respectivement sur l'allocation dynamique de stock avec une information sur l'état d'avancement de la production, sur l'allocation dynamique de stock avec une information avancée sur la demande et sur la gestion dynamique des prix dans un environnement économique fluctuant. Pour chacun des modèles, l'objectif est de déterminer la politique qui minimise les coûts actualisés ou moyens à horizon infini. Nous formulons ces problèmes comme des processus de décision markoviens et nous caractérisons la structure de la politique optimale. A partir de résultats numériques obtenus par itération sur la valeur, nous étudions, entre autres, l'influence de la variance du temps de production sur la performance, la valeur d'une information avancée sur la demande et le bénéfice lié à une gestion dynamique des prix.
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Olša, Petr. "Návrh řízení všesměrového mobilního robotu O3-X." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2010. http://www.nusl.cz/ntk/nusl-229210.
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This thesis deals with the design of a three-wheeled omni-directional robot control. The model of control is designed for robot´s omni-directional platform driven by maxon motor with the intelligent positioning controller EPOS. The design of control contains: - installation of the coordinated systems and transformation from one of them into another - design of system´s kinematical model - creation of classes for control and communication with EPOS - creation of the simulative program - planning of the mobile robot´s path - verification that the system is working The solution was based on continuous accelerated motion and the maximal acceleration of wheels was concerned, so that the slip would be suppressed. The function of the model was partly verified.
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Rajdl, Filip. "Virtuální zprovoznění výměníku nástrojů CNC stroje." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2020. http://www.nusl.cz/ntk/nusl-417784.
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The Master’s thesis deals with virtual commissioning of the CNC machine tool changer. First deals with current state of knowledge with a systematic analysis of virtual commissioning. The 3D model is created by physical properties, sensors, actuators and control signals. In the last part of this thesis, a PLC program and visualization is created. The programs needed to create a virtual commissioning are jsou NX 12.0 - Mechatronic concept designer, SIMIT Simulation Platform V10.0 a TwinCAT 3.
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Akhbari, Pouria. "Analysis of cellular transcriptomic changes induced by Merkel cell polyomavirus miRNA." Thesis, University of Bradford, 2017. http://hdl.handle.net/10454/15902.
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Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with rising global incidence. Merkel cell polyomavirus (MCV) was discovered in 2008 in 80% of MCC samples and since then a causal link between MCV and the majority of MCC cases has been established. microRNAs (miRNA, miR) are a family of small non-coding RNAs which play a key role in post-transcriptional regulation of gene expression and are considered significant players in disease and development in many species. Whilst the focus of MCV research has thus far been on the oncogenic MCV early proteins, large tumour (LT) and small tumour (sT) antigens, there is a knowledge gap regarding MCV miRNA and its functional significance in MCV pathogenesis. Given the emerging importance of viral miRNAs in virus-host interaction and pathogenesis, the aim of this doctoral research project was to investigate alterations in host cell transcripts induced by MCV miRNA and determine any functional significance these might have on virus-host cell interaction. RNA sequencing (RNA-Seq) in the presence and absence of MCV miRNA uncovered a multitude of downregulated cellular transcripts. Gene ontology analysis revealed that MCV miRNA targets transcripts associated with multiple cellular processes, however, regulation of immune response was overrepresented in our datasets. Validation of RNA-Seq data using MCV miRNA mimics and a synthetic, fully replicative MCV genome (MCVSyn) confirmed RNA-Seq data at mRNA and protein expression level for several targets, including the cytokine stimulating gene, SP100, and the neutrophil stimulator chemokine, CXCL8. Moreover, dual luciferase assays revealed that SP100 and MAPK10 (a member of mitogen-activated protein kinases (MAPK) family which is involved in regulation of CXCL8 expression) are directly and specifically targeted and downregulated by MCV miRNA. The MCV miRNA-dependent dysregulation of CXCL8 secretion is associated with impaired neutrophil migration, suggesting that the virus miRNA may be implicated in evasion of the host immune response.
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Nunes, da Silva Ramos Filipe José. "Identification of Suitable Areas for Offshore Macroalgae Cultivation." Thesis, KTH, Hållbar utveckling, miljövetenskap och teknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-243911.
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Research in sustainable macroalgae aquaculture has been gaining hype (e.g. Seafarm) to provide advancements in new significant sources of food, feed, materials and bio-energy. Despite the fact that in Asia the offshore production of macroalgae is established for many decades, in Europe is still in its infancy. The issue on where to find suitable cultivation areas without conflicting with current uses to respect the environment and the socio-economic activities is a great challenge. This Master of Science thesis aimed to find suitable offshore areas in order to facilitate implementations of macroalgae cultivations in the Swedish West Coast. Thirteen criteria in environmental, economic and social sustainability aspects were identified and employed (e.g. Depth, Distance to Ports, and Natural and Preserved areas (NPAs)), and the tools Geographic Information Systems (GIS) and Multi-criteria Analysis (MCA) were used in the form of GIS-MCDA, an integrated method available in Idrisi. To aggregate the criteria, Boolean and Weighted Linear Combination (WLC) techniques were applied. The results showed that Boolean areas cover 537 km2 (6,98% of the study area). The best suitable areas, possessing the maximum suitability index 10, that resulted from two WLC models comprise 5 km2 (0,07% of the study area) and 26 km2 (0,34% of the study area) including and excluding the criterion NPAs as constraint, respectively. The results further indicated that GIS-MCDA models excelled in providing an overview for effective spatial decision-making. Both techniques play a role in suitability analysis and complement each other in finding an optimal site which could be carefully selected out of the identified areas. It is recommended that areas with a suitability index 10 be chosen inside Boolean suitable areas. Moreover, this study could act as a driving force to build a resilient planning framework that would boost sustainable placement and development of offshore macroalgae cultivations.
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Chinenyeze, Samuel Jaachimma. "Mango : a model-driven approach to engineering green Mobile Cloud Applications." Thesis, Edinburgh Napier University, 2017. http://researchrepository.napier.ac.uk/Output/976572.
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With the resource constrained nature of mobile devices and the resource abundant offerings of the cloud, several promising optimisation techniques have been proposed by the green computing research community. Prominent techniques and unique methods have been developed to offload resource/computation intensive tasks from mobile devices to the cloud. Most of the existing offloading techniques can only be applied to legacy mobile applications as they are motivated by existing systems. Consequently, they are realised with custom runtimes which incur overhead on the application. Moreover, existing approaches which can be applied to the software development phase, are difficult to implement (based on manual process) and also fall short of overall (mobile to cloud) efficiency in software qualityattributes or awareness of full-tier (mobile to cloud) implications. To address the above issues, the thesis proposes a model-driven architecturefor integration of software quality with green optimisation in Mobile Cloud Applications (MCAs), abbreviated as Mango architecture. The core aim of the architecture is to present an approach which easily integrates software quality attributes (SQAs) with the green optimisation objective of Mobile Cloud Computing (MCC). Also, as MCA is an application domain which spans through the mobile and cloud tiers; the Mango architecture, therefore, takesinto account the specification of SQAs across the mobile and cloud tiers, for overall efficiency. Furthermore, as a model-driven architecture, models can be built for computation intensive tasks and their SQAs, which in turn drives the development – for development efficiency. Thus, a modelling framework (called Mosaic) and a full-tier test framework (called Beftigre) were proposed to automate the architecture derivation and demonstrate the efficiency of Mango approach. By use of real world scenarios/applications, Mango has been demonstrated to enhance the MCA development process while achieving overall efficiency in terms of SQAs (including mobile performance and energy usage compared to existing counterparts).
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Doherty, Rachel Veronica Mary. "Interaction of α-melanocyte stimulating hormone and its analogues with the human melanocortin receptor subtypes, MC1-R and MC4-R." Thesis, University of Bath, 1996. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321820.
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Knispel, Lukáš. "Pokročilé plánování cesty robotu (RRT)." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-230248.
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Tato diplomová práce práce se zabývá plánováním cesty všesměrového mobilního robotu pomocí algoritmu RRT (Rapidly-exploring Random Tree – Rychle rostoucí náhodný strom). Teoretická část popisuje základní algoritmy plánování cesty a prezentuje bližší pohled na RRT a jeho potenciál. Praktická část práce řeší návrh a tvorbu v zásadě multiplatformní C++ aplikace v prostředí Windows 7 za použití aplikačního frameworku Qt 4.8.0, která implementuje pokročilé RRT algoritmy s parametrizovatelným řešičem a speciálním dávkovým režimem. Tento mód slouží k testování efektivnosti nastavení řešiče pro dané úlohy a je založen na post-processingu a vizualizaci výstupu měřených úloh pomocí jazyka Python. Vypočtené cesty mohou být vylepšeny pomocí zkracovacích algoritmů a výsledná trajektorie odeslána do pohonů Maxon Compact Drive všesměrové mobilní platformy pomocí CANopen. Aplikace klade důraz na moderní grafické uživatelské rozhraní se spolehlivým a výkonným 2D grafickým engine.
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Hernandes, Janete Capel. "Qualidade de vida e imagem corporal de mulheres que praticam dança do ventre." Universidade Federal de Goiás, 2018. http://repositorio.bc.ufg.br/tede/handle/tede/9105.
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Introduction:This thesis was elaborated on the basis of scientific articles. It is observed that women have undergone several changes in the social, family and professional fields, and have conquered spaces in society, which has been positive; on the other hand, this has negatively impacted their quality of life and their body image. In this context, belly dancing has been sought as an alternative to this problem. Objective: To analyze the quality of life and body image of women who practice belly dancing. Method: two articles. 1) Systematic review elaborated according to PRISMA (2009), of quantitative studies registered in electronic platforms, identified with the descriptors quality of life, dance and women, in Portuguese, English and Spanish, and published until June 30, 2017, in any local. The mean and standard deviation of the quality of life outcomes were compared, with a significant difference. We used reference management software and bias risk assessment. The article was prepared by two independent reviewers. 2) Cross-sectional study according to STROBE (2008), using a sociodemographic questionnaire, WHOQOL-bref and Body Shape Questionnaire (BSQ), Statistical Analysis of Chi-square, Cronbach's Alpha, Kruskal-Wallis and Spearman correlation, with significance level 5% (p <0.05). Results: 1) Review of nine randomized clinical trials that used four instruments to assess the quality of life of overweight, cancer, fibromyalgia or non-health-related women; age from 20 to 64 years old, practicing belly dancing, zumba, circular dance, and Dance Movement Therapy (DMT) for a period of three to sixteen weeks. Studies analyzed in subgroups, with significance in the results of eight of them, with improvements, mainly in the physical and psychological domains of quality of life, with the intervention of some type of dance for at least eight weeks. 2) A cross-sectional study with 98 women, mean age of 32.8 (± 10.4) years. Among those surveyed, 89.8% had no concern with body image; 7.1% showed mild concern; and 3.1%, moderate concern. The following were found: positive correlation between the preoccupation with body image and BMI (r = 0.52, p <0.01); (r = -0.50, p <0.001) and environmental (r = - 0.35, p = 0.02) in women who practiced dancing for less than one year, and in the social domain (r = - 0.61, p = 0.01), those who practiced dance for six years or more; and positive correlation between the environmental domain (r = 0.29, p = 0.01) and dance time. Conclusions: In the systematic review, it was verified that dance improves the quality of life of adult women in the physical and psychological domains, when practiced at least twice a week, for at least eight weeks. In the cross-sectional study, there was a positive correlation between preoccupation with body image and measures of BMI, and between time of belly dance practice and quality of life; and negative correlation between quality of life and preoccupation with body image.
Introdução: Esta tese foi elaborada com base na modalidade artigos científicos. Observa-se que as mulheres têm passado por várias mudanças nos campos social, familiar e profissional, e conquistado espaços na sociedade, o que tem sido positivo; por outro lado, isso tem impactado negativamente a qualidade de vida e a imagem corporal delas. Neste contexto, a dança do ventre tem sido procurada como alternativa a essa problemática. Objetivo: Analisar a qualidade de vida e a imagem corporal de mulheres que praticam dança do ventre. Método: dois artigos. 1) Revisão sistemática elaborada conforme o PRISMA (2009), de estudos quantitativos registrados em plataformas eletrônicas, identificados com os descritores qualidade de vida, dança e mulheres, em português, inglês e espanhol, e publicados até 30 de junho de 2017, em qualquer local. Comparou-se a média e o desvio padrão dos resultados de qualidade de vida, com diferença significativa. Foram utilizados os softwares de gerenciamento de referências e avaliação do risco de viés. O artigo foi elaborado por dois revisores independentes. 2) Estudo transversal conforme o STROBE (2008), tendo como base: aplicação de questionário sociodemográfico, WHOQOL-bref e Body Shape Questionnaire (BSQ), Análise Estatística de Qui-quadrado, Alfa de Cronbach, Kruskal-Wallis e correlação de Spearman, com nível de significância 5% (p < 0,05). Resultados: 1) Revisão de nove ensaios clínicos randomizados, que utilizaram quatro instrumentos para avaliar a qualidade de vida de mulheres com sobrepeso, câncer, fibromialgia ou que não relataram problemas de saúde; idade de 20 a 64 anos, praticantes de dança do ventre, zumba, dança circular, biodança e Terapia pela Dança Movimento (TDM), por um período de três a dezesseis semanas. Estudos analisados em subgrupos, com significâncias nos resultados de oito deles, com melhorias, principalmente nos domínios físicos e psicológicos de qualidade de vida, com a intervenção de algum tipo de dança por, no mínimo, oito semanas. 2) Estudo transversal com 98 mulheres, idade média de 32,8 (± 10,4) anos. Dentre as pesquisadas, 89,8% não apresentaram preocupação com a imagem corporal; 7,1% demonstraram preocupação leve; e 3,1%, preocupação moderada. Foram constatadas: correlação positiva entre a preocupação com a imagem corporal e o IMC (r = 0,52; p < 0,01); correlação negativa entre a preocupação com a imagem corporal e os domínios psicológico (r = - 0,50; p < 0,001) e ambiental (r = - 0,35; p = 0,02) em mulheres que praticam a dança há menos de um ano, e, no domínio social (r = - 0,61; p = 0,01), entre aquelas que praticam a dança há seis anos ou mais; e correlação positiva entre o domínio ambiental (r = 0,29; p = 0,01) e o tempo de dança. Conclusões: Na revisão sistemática, verificou-se que a dança melhora a qualidade de vida de mulheres adultas nos domínios físicos e psicológicos, quando praticada ao menos duas vezes por semana, por, no mínimo, oito semanas. No estudo transversal, houve correlação positiva entre preocupação com a imagem corporal e medidas do IMC, e entre tempo de prática de dança do ventre e qualidade de vida; e correlação negativa entre qualidade de vida e preocupação com a imagem corporal.
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Lindström, Alexander. "Androidapplikation – MAD." Thesis, Umeå universitet, Institutionen för tillämpad fysik och elektronik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-58128.
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Företaget Acino AB har en tjänst för lagring och hantering av dokument på internet. Acino vill ha en Androidapplikation för denna service för att lättare kunna hantera dessa dokument i mobila enheter.I denna rapport går att läsa om utvecklingen av Androidapplikationen för tjänsten Mediaarkivet documents (refereras som MAD) som ägs av företaget Acino AB. I rapporten finns beskrivet teorin bakom de delar som används i Androidapplikationen och genomförandet av utvecklingen av den. Bakgrunden till projektet samt information om beställare finns också beskrivet i rapporten. Projektet har utförts enligt projektmetoden Scrum och arbetats i sprinter.Applikationen hanterar dokument hämtade över nätverk och kan visa dem samt ändra information om dessa. Applikationen är utvecklad efter den befintliga produktens design och arbetar mot en webbtjänst. Själva utvecklingen har skett i programvaran Eclipse. Applikationen har möjlighet att starta en service hos Androidenheten som lyssnar efter push-meddelanden från servern. Dessa meddelanden rapporterar om påminnelser och nya dokument och läggs i Androidenhetens meddelandefält. I rapporten går att läsa detaljerat om särskilda svårigheter som har uppstått under utförandet och som har varit väsentliga för applikationens lösning.Kravspecifikation och test från projektets utveckling finns som bilaga till rapporten. Utförliga testplaner finns även som bilaga där de olika delarna av applikationen har testats och fått ett godkännande. Projektet har varit väldigt lyckat där de flesta krav har uppfyllts.The corporation Acino AB has a service for storing and handling documents on the internet. Acino wants an Android application for this service for easier handle of documents on mobile devices.This report describes the development of an Android application for the service Mediaarkivet documents (referred to as MAD), owned by Acino AB. The report describes the theory behind the parts used in the Android application and implementation of the development of the latter. The background to the project, as well as information about the customer, is also described in the report. This project was executed according to the project method Scrum and worked in sprints.The application handles documents retrieved from a web service and is able to view them and change the information about them. The application is developed to match the existing product design and working towards a web service. The development has been done with Eclipse. The application can start a service on the Android device that listens for push messages from the server. These messages can contain memos or reports on new documents and will be placed in the Android device’s status bar. The report also includes details on specific difficulties encountered and designs that are essential for the application.Specification and test from the project development are annexed to the report. Detailed test plans are also available as an annex where the different parts of the application has been tested and approved. The project was a great success where most of the specifications have been fulfilled.
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莊柔玉 and Rouyu Zhuang. "Mad pursuit." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1990. http://hub.hku.hk/bib/B31209683.
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Brunton, Adam North. "MCP optics." Thesis, University of Leicester, 1994. http://hdl.handle.net/2381/35847.
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This thesis is an account of research into a novel type of X-ray optic - the microchannel plate (MCP). Experiments to determine the point to point focusing properties of square pore MCPs manufactured by Galileo Electro-Optics and Philips Photonics are reported. These were performed both in a test chamber at Leicester with an electron-bombardment X-ray source and with a laser-plasma X-ray source at the Rutherford Appleton Laboratory. A resolution of 6 arcmin and an intensity gain of 20 were recorded using a Galileo focusing MCP. An invesigation into the focusing action of MCPs which have been curved to a spherical figure is detailed. Such curved MCPs may, in a manner reminiscent of a conventional refractive lens, be used to focus a parallel X-ray beam to a point forming the basis of an X-ray telescope, or conversely to convert the diverging beam from a point-like X-ray source to a quasi-parallel one. The curving experiments were performed by Philips Photonics on standard circular pore MCPs. Tests on these plates were performed at Leicester; the results appear favourable. The technique has been applied to MCPs of up to 4mm thickness, curving them to a radius of 1.4m (0.7m focal length). A comprehensive Monte Carlo ray-tracing model is presented. This was initially developed to facilitate an understanding of the geometry of MCP focusing and to produce idealised images corresponding to a given experimental set up. These perfect images may be compared with, or used to predict experimental results. Comparison with experimental results led to incorporation of MCP distortions into the code. These distortions have been found by a programme of metrology which is also described. The model has led to a clear insight into the causes of poor image quality and their relative importance.
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Tanaka, Hiroki. "Zeeman Splitting Caused by Localized sp-d Exchange Interaction in Ferromagnetic GaMnAs Observed by Magneto-Optical Characterization." Ohio University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1441982108.
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Ahir, Nisha. "Mahatma Gandhi, M.D.?" Miami University Honors Theses / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=muhonors1111688178.
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Jacobsson, Madeleine. "Dr. Eleine Mad." Thesis, Kungl. Konsthögskolan, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kkh:diva-587.
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Dr. Eleine Mad är Madeleine Jacobsssons talesperson för dom vetenskapliga och paranormala upptäckter som uppstår i hennes världar. Hon beskriver innehåll, teknik och estetik utifrån ett kategoriseringssytem där konsten delas upp som olika typer av komponenter och därefter avkodas dessa allteftersom. För att förstå intuitionens inblandning i arbetsprocessen omförvandlas den till tre separata roller av en Sökare, Samlare och Myntare. Med rollerna försöker jag beskriva på vilka sätt som intuitionen är till gagn eller av förödelse för det konstnärliga arbetet. Sagan om M handlar om en grodlik karaktär, Delop, som lämnar sin hemplanet för att uppsöka andra världar. I sitt sökande hittar Delop ett folkslag vars syn och levnadssätt skiljer sig från hennes erfarenheter av “verkligheten” såsom hon lärt sig att överleva i den.Dr. Eleine Mad is Madeleine Jacobsson's spokesperson for the scientific and paranormal discoveries that arise in her worlds. She describes content, tecniques and aesthetics based on a categorization system where art is divided into different types of components and then decoded as they go. To understand the intuition's involvement in the work process, it is transformed into three separate roles by a Seeker, Collector and a Myntare(In swedish language the one who is a "myntare" -is verbally declaring a concept or term). With these roles I try to describe in what ways intuition is beneficial or devastating to the artistic work. The story of M is about a frog-like character, Delop, who leaves the home planet to seek out other worlds. In her search, Delop finds a world whose views and lifestyles differ from her experiences of "reality" as she learned to survive in it.
Recorded sound and image material of the presentation is available for private use.