Relevant bibliographies by topics / MCM paradox

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'MCM paradox'

Author: Grafiati
Published: 4 June 2021
Last updated: 18 February 2022

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Journal articles on the topic "MCM paradox"

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Das, Mitali, Sunita Singh, Satyajit Pradhan, and Gopeshwar Narayan. "MCM Paradox: Abundance of Eukaryotic Replicative Helicases and Genomic Integrity." Molecular Biology International 2014 (October 19, 2014): 1–11. http://dx.doi.org/10.1155/2014/574850.

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As a crucial component of DNA replication licensing system, minichromosome maintenance (MCM) 2–7 complex acts as the eukaryotic DNA replicative helicase. The six related MCM proteins form a heterohexamer and bind with ORC, CDC6, and Cdt1 to form the prereplication complex. Although the MCMs are well known as replicative helicases, their overabundance and distribution patterns on chromatin present a paradox called the “MCM paradox.” Several approaches had been taken to solve the MCM paradox and describe the purpose of excess MCMs distributed beyond the replication origins. Alternative functions
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De Schutter, Alban, Carl J. Lavie, Dharmendrakumar A. Patel, and Richard V. Milani. "Obesity paradox and the heart." Current Opinion in Clinical Nutrition and Metabolic Care 16, no. 5 (2013): 517–24. http://dx.doi.org/10.1097/mco.0b013e328363bcca.

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Ades, Philip A., and Patrick D. Savage. "The Obesity Paradox: Perception vs Knowledge." Mayo Clinic Proceedings 85, no. 2 (2010): 112–14. http://dx.doi.org/10.4065/mcp.2009.0777.

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Prado, Carla M., M. Cristina Gonzalez, and Steven B. Heymsfield. "Body composition phenotypes and obesity paradox." Current Opinion in Clinical Nutrition and Metabolic Care 18, no. 6 (2015): 535–51. http://dx.doi.org/10.1097/mco.0000000000000216.

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Kalantar-Zadeh, Kamyar, Tamara B. Horwich, Antigone Oreopoulos, et al. "Risk factor paradox in wasting diseases." Current Opinion in Clinical Nutrition and Metabolic Care 10, no. 4 (2007): 433–42. http://dx.doi.org/10.1097/mco.0b013e3281a30594.

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Guenette, Jordan A., Dennis Jensen, and Denis E. OʼDonnell. "Respiratory function and the obesity paradox." Current Opinion in Clinical Nutrition and Metabolic Care 13, no. 6 (2010): 618–24. http://dx.doi.org/10.1097/mco.0b013e32833e3453.

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Lee, Jieun, Kwangil Yim, Dong-Min Kim, Young-Seok Song та Ahwon Lee. "miR-106b-5p, miR-17-5p to predict recurrence and progression in breast DCIS model based on TGFβ paradox." Journal of Clinical Oncology 35, № 15_suppl (2017): e23019-e23019. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e23019.

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e23019 Background: Ductal carcinoma in situ (DCIS) is a well-known precursor of invasive ductal carcinoma (IDC). Part of patients show disease recurrence as DCIS or IDC after local treatment, but there are no established markers for prediction of recurrence. Methods: Authors analyzed 30 patients diagnosed as pure DCIS, recurrent DCIS, and IDC progressed in DCIS background. miRNA was extracted from archival tissue, and hierarchical clustering of miRNA microarray was performed. We selected highly expressed miR-17-5p and miR-106b-5p as marker for recurrence of DCIS. Two miRNAs were transfected to
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Pringle, Ramona. "Periscope's Paradox: The promise and peril of uncensored live video." IEEE Consumer Electronics Magazine 5, no. 4 (2016): 101–2. http://dx.doi.org/10.1109/mce.2016.2590582.

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Thornton, Daniel L. "Tests of the Expectations Hypothesis: Resolving the Campbell-Shiller Paradox." Journal of Money, Credit, and Banking 38, no. 2 (2006): 511–42. http://dx.doi.org/10.1353/mcb.2006.0036.

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Lavie, Carl J., Sergey Kachur, and Alban De Schutter. "Is there an obesity paradox in coronary heart disease in Asia?" Coronary Artery Disease 28, no. 4 (2017): 273–74. http://dx.doi.org/10.1097/mca.0000000000000471.

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Dissertations / Theses on the topic "MCM paradox"

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Marinsek, Nina. "Human GINS : a conserved DNA replication factor and candidate cancer marker." Thesis, University of Cambridge, 2010. https://www.repository.cam.ac.uk/handle/1810/236123.

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The GINS complex (a heterotetramer of Sld5, Psf1, Psf2 and Psf3) is a highly conserved DNA replication factor required for the initiation and elongation of DNA replication. GINS is believed to associate with Cdc45 and MCM proteins on replicating DNA. The interaction between GINS and MCM is also conserved in archaea. In my thesis, I explore the subcellular localisation of the GINS complex in relation to the MCM proteins and sites of DNA replication by high-resolution confocal microscopy. For these studies, I generated and carefully validated purified rabbit polyclonal and mouse monoclonal antib
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Sapin, Émilie. "Étude anatomique des réseaux neuronaux impliqués dans la régulation du sommeil paradoxal chez le rat." Thesis, Lyon 1, 2009. http://www.theses.fr/2009LYO10064.

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L’objectif de notre étude est d’améliorer la connaissance des réseaux neuronaux responsables de la régulation du sommeil paradoxal (SP). Dans ce but, nous avons combiné des techniques de polysomnographie, de neuroanatomie fonctionnelle, de pharmacologie et de traçage de voies nerveuses. Nous avons ainsi mis en évidence une population de neurones GABAergiques à la jonction entre la substance grise périaqueductale ventrolatérale et la partie dorsale du noyau profond du mésencéphale (vlPAG/dDpMe), capable de bloquer l’entrée en SP. Nous avons également démontré l’existence de nombreuses populatio
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Clément, Olivier. "L'hypothalamus latéral contiendrait le générateur principal du sommeil paradoxal : arguments neuroanatomiques et pharmacologiques chez le rat." Phd thesis, Université Claude Bernard - Lyon I, 2011. http://tel.archives-ouvertes.fr/tel-00739636.

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Les mécanismes neurologiques responsables du déclenchement et de l'homéostasie du sommeil, et du sommeil paradoxal (SP) en particulier, sont l'objet d'un nombre toujours plus important d'études du fait notamment de l'attention croissante portée aux pathologies associées. Les travaux rapportés dans cette thèse s'inscrivent parfaitement dans cette dynamique puisqu'ils ont pour objectif de mieux caractériser les populations neuronales mises en jeu dans la régulation du SP ainsi que leurs interactions. Dans cette optique, nous avons combiné différentes approches techniques complémentaires à savoir
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Varin, Christophe. "Contribution de noyaux hypothalamiques et de leur interconnexion à la régulation du sommeil." Thesis, Lyon, 2016. http://www.theses.fr/2016LYSE1049/document.

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Chez les mammifères, l’alternance des états de vigilance nécessite la mise en jeu de mécanismes spéci ques qui facilitent les transitions entre l’éveil, le sommeil lent (SL) et le sommeil paradoxal (SP). L’objectif de cette thèse s’inscrit dans l’optique de disséquer chez la souris les processus neuronaux contrôlant l’alternance physiologique entre ces trois états de vigilance. Au cours de cette thèse, nous avons tout d’abord démontré par des approches complémentaires ex vivo et in vivo que le glucose peut favoriser l’endormissement par son action excitatrice directe sur les neurones promoteur
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Le, Barillier Léa. "Rôle du sommeil paradoxal dans des formes de mémoire dépendantes de l'hippocampe : une étude chez la souris de la neuromodulation par l'Hormone de Mélano- Concentration et des réseaux corticaux." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10010/document.

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Il est maintenant établi que le sommeil paradoxal (SP) facilite certaines formes de mémoires dépendantes de l'hippocampe bien que les mécanismes impliqués restent mal compris. Des résultats de l'équipe et d'autres laboratoires suggèrent toutefois que cet effet facilitateur serait en partie sous-tendu par une modulation de la plasticité synaptique de longue durée dans l'hippocampe. Nos travaux se proposent donc d'étudier ces mécanismes chez la souris, à l'échelle synaptique et systémique. Pour cela nous nous avons privilégié trois approches : 1) La caractérisation comportementale et électrophys
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Setegn, Shimelis Gebriye. "Hydrological and sediment Yield modelling in Lake Tana Basin, Blue Nile Ethiopia." Licentiate thesis, Stockholm : Mark- och vattenteknik, Land and Water Resource Engineering, Kungliga Tekniska högskolan, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4796.

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Books on the topic "MCM paradox"

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Wittman, David M. The Elements of Relativity. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199658633.001.0001.

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Relativity is a set of remarkable insights into the way space and time work. The basic notion of relativity, first articulated by Galileo, explains why we do not feel Earth moving as it orbits the Sun and was successful for hundreds of years. We present thinking tools that elucidate Galilean relativity and prepare us for the more modern understanding. We then show how Galilean relativity breaks down at speeds near the speed of light, and follow Einstein’s steps in working out the unexpected relationships between space and time that we now call special relativity. These relationships give rise
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Silva, Fabio José Antonio da. Cogito Ergo “SUS”: relatos de experiencias de profissionais de educação física no SUS. Editora Amplla, 2021. http://dx.doi.org/10.51859/amplla.ces399.1121-0.

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Falar da atuação do Profissional de Educação Física no SUS para mim é um prazer e um dever. PRAZER porque é bom falar daquilo que gostamos e o DEVER onde me cabe apontar, fiscalizar e promover as ações e dar visibilidade a nossa profissão da melhor maneira possível. Ver o quanto podemos fazer na saúde pública e não ter isso registrado, formalizado, foi pra mim a mola propulsora para organizar esse e-book. Confesso que desde o princípio sabia que ia dar certo. Quando comecei a entrar em contato com os colegas de outros estados, pude sentir em suas vozes a certeza de que queiram a mesma coisa qu
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Book chapters on the topic "MCM paradox"

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Huang, Chi-Yo, Hsin-Hung Wu, and Hsueh-Hsin Lu. "A MCDM Methods Based TAM for Deriving Influences of Privacy Paradox on User’s Trust on Social Networks." In Trends in Applied Knowledge-Based Systems and Data Science. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-42007-3_30.

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McHugh, Dominic. "After The Music Man." In The Big Parade. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780197554739.003.0006.

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It was difficult for Willson to choose a follow-up to The Music Man because it was such a big hit. This chapter charts his struggles with his second musical The Unsinkable Molly Brown, including the problems with the show’s director, Dore Schary, which are revealed through newly uncovered production documents. The musical is based on the real life exploits of Molly Brown, who survived the sinking of the Titanic, and was a modest success upon its debut on Broadway. The chapter also briefly explores the 1964 MGM film adaptation starring Debbie Reynolds.
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Conference papers on the topic "MCM paradox"

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Zhang, Yi, and Jitao Sang. "Towards Accuracy-Fairness Paradox." In MM '20: The 28th ACM International Conference on Multimedia. ACM, 2020. http://dx.doi.org/10.1145/3394171.3413772.

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Quiles Zamora, Vicente, Eduardo Iáñez, Mario Ortiz, and José María Azorín. "Estudio preliminar de la detección de cambios de velocidad de la marcha a partir de señales EEG." In 11 Simposio CEA de Bioingeniería. Editorial Universitat Politècnica de València, 2019. http://dx.doi.org/10.4995/ceabioing.2019.10034.

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El análisis de las señales cerebrales para la asistencia en pacientes con movilidad reducida es un área de investigación continua en la que las nuevas tecnologías ofrecen un amplio espectro de posibilidades para la ayuda activa como los exoesqueletos y las interfaces cerebro-maquinas (BMI). En este trabajo nos centramos en realizar una interfaz BMI para el control de velocidad del miembro inferior. El objetivo de este estudio es analizar las señales electroencefalográficas (EEG) para obtener un indicador que relacione la información cerebral con marcadores de velocidad en la marcha. Para el pr
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Journal articles
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