Relevant bibliographies by topics / MCOPS12

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'MCOPS12'

Author: Grafiati
Published: 3 May 2025
Last updated: 19 July 2025

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Journal articles on the topic "MCOPS12"

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Rakes, Christopher R., Michele L. Stites, Robert N. Ronau, et al. "Teaching Mathematics with Technology: TPACK and Effective Teaching Practices." Education Sciences 12, no. 2 (2022): 133. http://dx.doi.org/10.3390/educsci12020133.

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This paper examines how 17 secondary mathematics teacher candidates (TCs) in four university teacher preparation programs implemented technology in their classrooms to teach for conceptual understanding in online, hybrid, and face to face classes during COVID-19. Using the Professional Development: Research, Implementation, and Evaluation (PrimeD) framework, TCs, classroom mentor teachers, field experience supervisors, and university faculty formed a Networked Improvement Community (NIC) to discuss a commonly agreed upon problem of practice and a change idea to implement in the classroom. Through Plan-Do-Study-Act cycles, participants documented their improvement efforts and refinements to the change idea and then reported back to the NIC at the subsequent monthly meeting. The Technology Pedagogical Content Knowledge framework (TPACK) and the TPACK levels rubric were used to examine how teacher candidates implemented technology for Mathematics conceptual understanding. The Mathematics Classroom Observation Protocol for Practices (MCOP2) was used to further examine how effective mathematics teaching practices (e.g., student engagement) were implemented by TCs. MCOP2 results indicated that TCs increased their use of effective mathematics teaching practices. However, growth in TPACK was not significant. A relationship between TPACK and MCOP2 was not evident, indicating a potential need for explicit focus on using technology for mathematics conceptual understanding.
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Gleason, Jim, Stefanie Livers, and Jeremy Zelkowski. "Mathematics Classroom Observation Protocol for Practices (MCOP2): A validation study." Investigations in Mathematics Learning 9, no. 3 (2017): 111–29. http://dx.doi.org/10.1080/19477503.2017.1308697.

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Rogers, Kimberly Cervello, Robert Petrulis, Sean P. Yee, and Jessica Deshler. "Mathematics Graduate Student Instructor Observation Protocol (GSIOP): Development and Validation Study." International Journal of Research in Undergraduate Mathematics Education 6, no. 2 (2019): 186–212. http://dx.doi.org/10.1007/s40753-019-00106-4.

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AbstractThis paper presents the development and validation of the 17-item mathematics Graduate Student Instructor Observation Protocol (GSIOP) at two universities. The development of this instrument attended to some unique needs of novice undergraduate mathematics instructors while building on an existing instrument that focused on classroom interactions particularly relevant for students’ development of conceptual understanding, called the Mathematical Classroom Observation Protocol for Practices (MCOP2). Instrument validation involved content input from mathematics education researchers and upper-level mathematics graduate student instructors at two universities, internal consistency analysis, interrater reliability analysis, and structure analyses via scree plot analysis and exploratory factor analysis. A Cronbach-Alpha level of 0.868 illustrated a viable level for internal consistency. Crosstabulation and correlations illustrate high level of interrater reliability for all but one item, and high levels across all subsections. Collaborating a scree plot with the exploratory factor analysis illustrated three critical groupings aligning with the factors from the MCOP2 (student engagement and teacher facilitation) while adding a third factor, lesson design practices. Taken collectively, these results indicate that the GSIOP measures the degree to which instructors’ and students’ actions in undergraduate mathematics classrooms align with practices recommended by the Mathematical Association of America (MAA) using a three-factor structure of teacher facilitation, student engagement, and design practices.
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Yang, Yuqin, Junjie Miao, Zhendong Yin, et al. "Synthesis of the Magnetically Nanoporous Organic Polymer Fe3O4@SiO2-NH2-COP and Its Application in the Determination of Sulfonamide Residues in Surface Water Surrounding a Cattle Farm." Bioinorganic Chemistry and Applications 2022 (April 23, 2022): 1–15. http://dx.doi.org/10.1155/2022/6453609.

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Efficient extractions of trace antibiotic residues in the environment are a key factor for accurate quantification of the residues. A new nanoporous material, namely, magnetically covalent organic polymer (MCOP, Fe3O4@SiO2-NH2-COP) was synthesized in this work and was used for magnetic solid-phase extraction (MSPE). The combination of MSPE with high-performance liquid chromatography separation together with ultraviolet detection (HPLC-UV) was established as an effective method for the determination of four sulfonamide (SA) residues in surface water surrounding a cattle farm. The synthesized magnetic material was characterized by SEM, TEM, FT-IR, magnetic properties measurement system (MPMS), and nitrogen gas porosimetry. The material possessed many attractive features, such as a unique microporous structure, a larger specific surface area (137.93 m2·g−1) than bare Fe3O4 (24.84 m2·g−1), high saturation magnetization (50.5 emu·g−1), open adsorption sites, and high stability. The influencing parameters, including pH, the used amount of MCOPs, the type of eluent, adsorption solution, and desorption time, were optimized. Under the optimized conditions, the method conferred good linearity ranges (R2 ≥ 0.9990), low detection limits (S/N = 3, LOD, 0.10–0.25 μg·L−1), and satisfactory recoveries (79.7% to 92.2%). The enrichment factor (EF) for the four SAs was 34.13–38.86. The relative standard deviations of intraday (n = 5) and of interday (n = 3) were less than 4.8% and 8.9%, respectively. The equilibria between extraction and desorption for SAs could be reached within 150 s. The proposed method was sensitive and convenient for detecting SA residues in complex environmental matrices, and the successful application of the new MCOPs as an adsorbent was demonstrated.
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Zelkowski, Jeremy, Bill Bergeron, Jim Gleason, Martha Makowski, and Robert Petrulis. "Developing Secondary Mathematics Teacher Leaders: A Multi-Year Curriculum for Inservice Teacher Excellence." Education Sciences 15, no. 7 (2025): 788. https://doi.org/10.3390/educsci15070788.

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In response to systemic inequities in mathematics education, we developed and evaluated a five-year, multi-phase curriculum model to cultivate effective secondary mathematics teacher leaders. Supported by NSF Noyce Master Teacher Fellowships, the APLUS in MATH (APLUS in Math: Alabama Practitioner Leaders for Underserved Schools in Mathematics) program engaged 22 inservice teachers through graduate coursework, National Board Certification preparation, and leadership project development. Using a mixed-methods design, we analyzed data from classroom observations (MCOP2), National Board Certification assessments, course performance ratings, and teacher leadership project proposals. Results indicate significant improvements in instructional practices, content knowledge, and leadership readiness. Findings underscore the importance for sustained, structured professional development to prepare teachers as instructional experts and change agents in high-need educational contexts.
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Wang, Zhihao, Ying Chen, Jiahe Zhao, et al. "Melamine-based Covalent Organic Polymers (MCOPs) as Lipase Nanocarrier for Recyclable Esters Hydrolysis and Transesterification." Journal of Oleo Science 69, no. 6 (2020): 627–34. http://dx.doi.org/10.5650/jos.ess20032.

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Abbott, Katherine, Jennifer Heston-Mullins, Athena Koumoutzis, Dayna Bennett, Karen Williams, and Robert Applebaum. "THE BLACK BOX OF CARE MANAGEMENT IN MANAGED LONG-TERM SERVICES AND SUPPORTS." Innovation in Aging 6, Supplement_1 (2022): 187–88. http://dx.doi.org/10.1093/geroni/igac059.749.

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Abstract Within Ohio’s MyCare demonstration, two distinct care management models were selected by the participating MyCare Ohio health plans (MCOPs): fully-delegated waiver care management and waiver service coordination. The purpose of this presentation is to describe the components of care management operating in MyCare Ohio. Qualitative interviews with n=91 Area Agency on Aging (AAA) and n=131 MCOP care management personnel were audio-recorded, transcribed, and checked for accuracy prior to thematic coding in Dedoose. Results indicate that comprehensive care management is the core element of MyCare Ohio. Fully-delegated care management models were viewed by participants as beneficial to reducing confusion for members however ‘scope creep’ challenged the already strained AAAs. Effective teamwork was identified for waiver service coordination models but the division of labor and communication needed between the AAA and MCOP care management personnel created tensions. The discussion will focus on practice recommendations for training, caseloads, and support staff.
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Rhodes, Guy M., Jason R. Ali, Ernie A. Hailwood, Chris King, and Tom G. Gibson. "Magnetostratigraphic correlation of Paleogene sequences from northwest Europe and North America." Geology 27, no. 5 (1999): 451. http://dx.doi.org/10.1130/0091-7613(1999)027<0451:mcopsf>2.3.co;2.

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Qiu, Qian-Qian, Wang-Kang Han, Ruo-Meng Zhu, Yong Liu, Jia-Xing Fu, and Zhi-Guo Gu. "Two‐Dimensional Metal Covalent Organic Polymers with Dirhodium(II) Photoreduction Centers for Efficient Nitrogen Fixation." ChemNanoMat, October 24, 2024. http://dx.doi.org/10.1002/cnma.202400462.

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Photocatalytic nitrogen fixation is a green method for converting N2 to NH3, but it remains a challenging task due to the lack of effective photocatalysts. Herein, a series of porous metal covalent organic polymers (MCOPs) with the integration of dinuclear rhodium(II) catalytic center were rationally constructed for photocatalytic N2 fixation. Interestingly, the porous MCOPs had double‐layers two‐dimensional (2D) structures with the coordinated Rh(II) as point of registry. The photocatalytic experiment showed that Rh‐TAPA with significant donor‐acceptor (D‐A) features exhibited a high activity toward NH3 production with a rate of 319.8 μmol g−1 h−1. The electron transfer process, N2 adsorption and activation mechanism of RhCOPs were further investigated through comprehensive characterisation, including DFT calculations and in situ characterization. This work provided a valuable insight into the photocatalytic N2 fixation process with porous materials.
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Lu, Fen, Xin Xu, Bixia Zheng, et al. "Case report: Expansion of phenotypic and genotypic data in TENM3-related syndrome: Report of two cases." Frontiers in Pediatrics 11 (February 24, 2023). http://dx.doi.org/10.3389/fped.2023.1111771.

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Biallelic TENM3 variants were recently reported to cause non-syndromic microphthalmia with coloboma-9 (MCOPCB9) and microphthalmia and/or coloboma with developmental delay (MCOPS15). To date, only eight syndromic and non-syndromic microphthalmia cases with recessive TENM3 variants have been reported. Herein, we report two unrelated new cases with biallelic variants in TENM3, widening the molecular and clinical spectrum. Regarding patient 1, WES revealed compound heterozygous variants in the TENM3 gene: c.3847_3855del; p.Leu1283_Ser1285del and c.3698_3699insA; p.Thr1233Thrfs*20 in the index patient, who was presenting with bilateral microphthalmia, congenital cataract, microcephaly, and global developmental delay. Regarding patient 2, compound missense heterozygous variants in the TENM3 gene were identified: c.941C &amp;gt; T; p.Ala314Val and c.6464T &amp;gt; C; p.Leu2155Pro in the 3-year-old boy, who presented with congenital esotropia, speech delay, and motor developmental delay. The clinical features of these two cases revealed high concordance with the previously reported cases, including microphthalmia and developmental delay. The presence of microcephaly in our patient potentially expands the neurologic phenotype associated with loss of function variants in TENM3, as microcephaly has not previously been described. Furthermore, we present evidence that missense variants in TENM3 are associated with similar, but milder, ocular features.
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Dissertations / Theses on the topic "MCOPS12"

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Semaan, Hanna. "Proteomic study of mechanisms, targets and potential treatments of neurological disorders associated with RARβ point mutations (MCOPS-12)". Electronic Thesis or Diss., Strasbourg, 2025. http://www.theses.fr/2025STRAJ007.

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La Microphtalmie Syndromique 12 (MCOPS12) est une maladie rare caractérisée par une gamme de symptômes cliniques, comprenant des déficiences intellectuelles et des troubles moteurs progressifs. MCOPS12 est causée par des mutations ponctuelles de novo dans le gène du récepteur de l'acide rétinoïque bêta (RARβ), un médiateur de la signalisation de la vitamine A essentiel au développement cérébral et aux fonctions neuronales. Les mécanismes physiopathologiques sous-jacents de cette maladie demeurent inconnus, et aucun traitement curatif n'est actuellement disponible. Par conséquent, l'objectif global de cette thèse est d'identifier les mécanismes potentiels contribuant à la physiopathologie de MCOPS12 et par la suite proposer des traitements pharmacologiques pour prévenir ou atténuer les symptômes associés. Plus précisément, ce travail utilise des approches protéomiques pour analyser l'impact des mutations du RARβ sur la composition de son complexe protéique ainsi que sur la communication neuronale dans le striatum. Notre étude a identifié un renforcement de la signalisation glutamatergique et dopaminergique dans le striatum des modèles murins de MCOPS12. La modulation pharmacologique de ces voies a montré des effets bénéfiques dans la normalisation de certains symptômes associés à cette maladie. De plus, nos résultats démontrent que différentes mutations du RARβ modifient la composition des protéines interagissant avec RARβ de manière spécifique à la mutation. L'altération des interactions avec les corégulateurs révélée dans des lignées cellulaires de neuroblastome humain pourrait être à l'origine du contrôle transcriptionnel perturbé, conduisant ainsi à MCOPS12<br>Syndromic Microphthalmia 12 (MCOPS12) is a rare syndromic disorder characterized by a range of clinical symptoms, including intellectual disabilities and progressive motor impairments. MCOPS12 is caused by de novo point mutations in the retinoic acid receptor beta (RARβ) gene, a mediator of vitamin A signaling essential for brain development and neural functions. Importantly, the underlying pathophysiological mechanisms of this disease remains unknown, and no curative treatment is currently available. Therefore, the overall aim of this thesis is to identify potential mechanisms contributing to MCOPS12 pathophysiology and to propose pharmacological treatments for preventing or alleviating associated symptoms. Specifically, this work employs proteomics approaches to interrogate the impact of RARβ mutations on the composition of RARϐ protein complex as well as on neuronal communication in the striatum. Our study identified enhanced glutamatergic and dopaminergic signaling in the striatum of MCOPS12 mouse models. Pharmacological targeting of these pathways showed some beneficial effects in normalizing selected MCOPS12-associated symptoms. Furthermore, our results demonstrate that different RARβ mutations alter composition of proteins interacting with RARϐ in a mutation-specific manner. Alteration of interactions with coregulators revealed in human neuroblastoma cell lines, may underlie to disrupted transcriptional control leading thereby to MCOPS12
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Book chapters on the topic "MCOPS12"

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Guo, Ying, Lianzhen Zheng, Yuhan Zhang, and Guanfeng Liu. "MCOPS-SPM: Multi-Constrained Optimized Path Selection Based Spatial Pattern Matching in Social Networks." In Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-48513-9_1.

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"MCOPS3." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_102220.

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Hilton, Emma, Graeme C. M. Black,, and Vivian Bardwell. "BCOR and Oculofaciocardiodental Syndrome." In Inborn Errors Of Development. Oxford University PressNew York, NY, 2008. http://dx.doi.org/10.1093/oso/9780195306910.003.0108.

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Abstract In 1980, Hayward described a female with canine (cuspid) radiculomegaly associated with congenital cataracts (Hayward, 1980). Further cases of individuals with similar dental anomalies and congenital cataracts were reported by Marashi and Gorlin (1990, 1992). Wilkie et al. (1993) proposed that this phenotype, in combination with distinctive cardiac and facial findings, comprised a novel syndrome and the term oculofaciocardiodental (OFCD) syndrome was recommended to refer to this disorder (Gorlin et al., 1996). Due to recent changes in nomenclature, OFCD syndrome is now referred to as syndromic microphthalmia 2 (MCOPS2; OMIM 300166). However, the term OFCD syndrome is used throughout this chapter. Since it was defined, the condition has been reported around 30 times, exclusively in females. In 2004, Ng et al. demonstrated that presumed null mutations in the X-linked BCL-6 corepressor (BCOR) gene, which encodes BCOR, are responsible for OFCD syndrome (Ng et al., 2004). Since those individuals tested have skewed inactivation in favor of the wild type allele, it is presumed that OFCD syndrome is X-linked dominant with male lethality. In addition to causing OFCD, a missense mutation in BCOR has been described in a single family with MCOPS2 (X-linked recessive Lenz microphthalmia syndrome), suggesting a correlation between mutation type and phenotype.
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Conference papers on the topic "MCOPS12"

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Niu, Chunling. "Examine the Mathematics Classroom Observation Protocol for Practices (MCOP2) Dimensionality Using the Many-Facet Rasch Modeling (Poster 4)." In 2022 AERA Annual Meeting. AERA, 2022. http://dx.doi.org/10.3102/1891746.

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