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Dissertations / Theses on the topic 'MD-2'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

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1

Divanovic, Senad. "Negative Regulation of TLR4/MD-2 Signaling by RP105/MD-1." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1124119013.

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2

Walsh, Catherine Margaret. "Contributions of equine TLR4 and MD-2 to Lipid A discrimination." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612193.

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3

Chokbunpiam, Tadija, Rungroi Chanajaree, Oraphan Saengsawang, et al. "Diffusion and adsorption of N 2 and C 2 H 6 in ZIF-8 MD and MC simulations." Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-183054.

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4

Chokbunpiam, Tadija, Rungroi Chanajaree, Oraphan Saengsawang, et al. "Diffusion and adsorption of N 2 and C 2 H 6 in ZIF-8 MD and MC simulations." Diffusion fundamentals 20 (2013) 47, S. 1-2, 2013. https://ul.qucosa.de/id/qucosa%3A13619.

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5

ZAFFARONI, LENNY. "Production of recombinant human MD-2 and development of protein-ligand binding assays for the characterization of new TLR4 modulators." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2018. http://hdl.handle.net/10281/207343.

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Il toll-like receptor 4 (TLR4) rappresenta un mediatore centrale dell’immunità innata ed adattativa in mammiferi. L’attivazione di TLR4 in risposta al lipopolisaccaride (LPS) batterico induce un rapido innesco di processi pro-infiammatori essenziali per una risposta immunitaria ottimale. L’attivazione di TLR4 mediata da LPS è un meccanismo che coinvolge la partecipazione di diverse proteine e culmina con la formazione del complesso attivato (TLR4/MD-2/LPS)2. MD-2 è il co-rettore di TLR4, e svolge un importante ruolo nell’interazione con LPS e la susseguente dimerizzazione del TLR4. MD-2 è la c

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6

Aguiar, Carla Carvalho de. "Caracterização da dinâmica da complexação do receptor tipo Toll 4 humano a MD-2." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/117886.

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Os receptores tipo Toll desempenham um importante papel na resposta imune inata, reconhecendo tanto padrões moleculares associados a patógenos (PAMPs), quanto padrões moleculares associados a danos (DAMPs), liberados sob condições de injúria ou estresse celular. O receptor tipo Toll 4 humano (hTLR4), associado ao seu co-receptor, o fator de diferenciação mielóide 2 (MD-2), forma um heterodímero caracterizado como responsável pelo reconhecimento de lipopolissacarídeos bacterianos (LPS), derivados de bactérias Gram-negativas. Nestes casos, sabe-se que o MD-2 reconhece LPS e promove a dimerização

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7

McBride, Daniel S. "Lie to Me: Malingered Depression on the MMPI-2." OpenSIUC, 2011. https://opensiuc.lib.siu.edu/theses/684.

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The Malingered Depression Scale (Md Scale; Steffan, Clopton, & Morgan, 2003) was recently developed for use with the MMPI-2 in attempts to distinguish individuals with genuine symptoms of depression from individuals who feign depression on the test. With respect to the Md scale, a relative lack of research and mixed findings regarding its utility are problematic; therefore, these issues were explored. The predictive and incremental validity of the Md scale were tested in this study to determine if use of the Md scale conferred a distinct predictive advantage over standard validity scales (e.

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8

Eisenhauer, Kirstin Diana [Verfasser], Klaus [Gutachter] Gerwert, and Christian [Gutachter] Herrmann. "MD-Simulationen zur Aufklärung des molekularen Reaktionsmechanismus von Channelrhodopsin-2 / Kirstin Diana Eisenhauer. Gutachter: Klaus Gerwert ; Christian Herrmann." Bochum : Ruhr-Universität Bochum, 2016. http://d-nb.info/1112326693/34.

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9

Orbegoso, Pandal Carlos José. "Caracterización y calibración de películas radiocrómicas MD-55-2 y su utilización en la dosimetría de braquiterapia ocular." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2016. https://hdl.handle.net/20.500.12672/5986.

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Desarrolla la técnica de películas radiocrómicas en dosimetría de braquiterapia ocular, para un aplicador oftálmico de oro con fuentes en forma de pequeños hilos de Ir-192, teniendo en cuenta una buena precisión, sensibilidad, buena respuesta en el rango de aplicación, versatilidad en su manejo y otras cualidades. Por ello, el objetivo fundamental de esta tesis es mostrar las bondades de las películas radiocrómicas ya que poseen características apropiadas para la verificación de la dosimetría en pacientes.<br>Tesis

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10

Eisenhauer, Kirstin [Verfasser], Klaus [Gutachter] Gerwert, and Christian [Gutachter] Herrmann. "MD-Simulationen zur Aufklärung des molekularen Reaktionsmechanismus von Channelrhodopsin-2 / Kirstin Diana Eisenhauer. Gutachter: Klaus Gerwert ; Christian Herrmann." Bochum : Ruhr-Universität Bochum, 2016. http://d-nb.info/1112326693/34.

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11

Silva, Vânia Maria Barboza da. "Características de composição química e atividades da Peroxidase e da Polifenoloxidase dos cultivares de abacaxi MD-2 e Pérola." Universidade Federal da Paraíba, 2012. http://tede.biblioteca.ufpb.br:8080/handle/tede/4053.

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Made available in DSpace on 2015-04-17T14:49:27Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 1010253 bytes, checksum: 01946d09359090468de43eac2c0a9e39 (MD5) Previous issue date: 2012-07-12<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>Pineapple is a fruit widely appreciated as fresh fruit. But its chemical composition varies widely between different cultivars. This study evaluated the content of some chemical components and the activity of peroxidase and polyphenoloxidase in pineapple MD-2 and Pearl mature, comparing them with each other. The chemical componen

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12

Richard, Manuel. "Analyse de la composition élémentaire de Pecten maximus par HR-ICP-MD Element 2 : développements méthodologiques et interprétations écologiques." Brest, 2009. http://www.theses.fr/2009BRES2031.

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L’objectif de ce travail de thèse était de développer des méthodologies analytiques sur un spectromètre de masse haute résolution couplée à une source plasma (HR-ICP-MS Element 2 de Finigan) pour déterminer quantitativement des éléments en traces dans des matrices de carbonate de calcium. Deux méthodes (couplage LA-ICP-MS et analyse en mode liquide) ont été mises en places afin de placer sur une échelle calendaire (± 3 jours) les variations ontogéniques des teneurs élémentaires dans les valves de P. Maximus. Les résultats d’analyses obtenus sur une même valve gauche par les deux méthodes, mont

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13

CIGHETTI, ROBERTO. "Design, synthesis and biological characterization of new small-molecule TLR4 modulators." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/50753.

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L’attivazione del Toll-Like Receptor 4 (TLR4) e il conseguente signaling intracellulare in risposta a esigue quantità di endotossine (lipopolisaccaridi di batteri Gram-negativi, LPS) presenti nel circolo sanguigno porta al rapido innesco di processi pro-infiammatori necessari per una risposta immunitaria ottimale dell’organismo ospite contro l’invasione di batteri Gram-negativi. Il TLR4 non lega però direttamente i LPS e la sua attivazione da parte dell’endotossina è un processo complesso che prevede la partecipazione di altre proteine che legano i LPS (LBP, CD14 e MD-2) e porta infine alla f

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14

Pezzotti, Simone. "DFT-MD simulations and theoretical SFG spectroscopy to characterize H-Bonded networks at aqueous interfaces : from hydrophobic to hydrophilic environments Structural definition of the BIL and DL: a new universal methodology to rationalize non-linear χ(2)(ω) SFG signals at charged interfaces, including χ(3)(ω) contributions What the Diffuse Layer (DL) Reveals in Non-Linear SFG Spectroscopy 2D H-Bond Network as the Topmost Skin to the Air-Water Interface Combining ab-initio and classical molecular dynamics simulations to unravel the structure of the 2D-HB-network at the air-water interface 2D-HB-Network at the air-water interface: A structural and dynamical characterization by means of ab initio and classical molecular dynamics simulations Spectroscopic BIL-SFG Invariance Hides the Chaotropic Effect of Protons at the Air-Water Interface Molecular hydrophobicity at a macroscopically hydrophilic surface Graph theory for automatic structural recognition in molecular dynamics simulations DFT-MD of the (110)-Co3O4 cobalt oxide semiconductor in contact with liquid water, preliminary chemical and physical insights into the electrochemical environment". Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLE008.

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Améliorer notre connaissance de la structure de l'eau dans l'environnement spécial offert par une interface est essentiel pour la compréhension de nombreux phénomènes naturels et applications technologiques. Pour révéler cette structure interfaciale de l'eau, des techniques capables de fournir des informations microscopiques, de manière sélective, pour cette couche interfaciale (BIL) sont nécessaires. Dans le présent travail de thèse, nous avons donc étudié les interfaces aqueuses au niveau moléculaire, en couplant la modélisation théorique à partir de simulations DFT-MD avec les spectroscopie

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15

Gebus, Adrien. "From lipid-mediated molecular interactions to a synergistic antimicrobial activity : a study of PGLa and magainin 2 amphipathic peptides using NMR spectroscopy and in silico molecular dynamics simulations." Electronic Thesis or Diss., Strasbourg, 2024. http://www.theses.fr/2024STRAF017.

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PGLa et magainin 2 sont deux peptides amphiphiles, avec une activité antimicrobienne synergique. Nous avons étudié la structure et la dynamique de ces peptides, ainsi que leurs interactions avec les membranes. Par spectroscopie RMN en phase solide et liquide nous avons obtenu des informations sur la structure de PGLa dans un environnement hydrophobe.Un modèle 3D de PGLa en micelles a été construit, et différentes populations de PGLa en bicouche lipidique on été identifiées. Des simulations de MD ont permis d'étudier l'interaction de PGLa et magainin 2 entre eux et avec avec la membrane. Nous e

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16

Ensor, Lael J. "Decoration in early Qur'an manuscripts: A close look at the Walters Art Museum's W.554." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 56 p, 2009. http://proquest.umi.com/pqdweb?did=1885754571&sid=3&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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17

Durán, Alcaide Ángel. "Development of high-performance algorithms for a new generation of versatile molecular descriptors. The Pentacle software." Doctoral thesis, Universitat Pompeu Fabra, 2010. http://hdl.handle.net/10803/7201.

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The work of this thesis was focused on the development of high-performance algorithms for a new generation of molecular descriptors, with many advantages with respect to its predecessors, suitable for diverse applications in the field of drug design, as well as its implementation in commercial grade scientific software (Pentacle). As a first step, we developed a new algorithm (AMANDA) for discretizing molecular interaction fields which allows extracting from them the most interesting regions in an efficient way. This algorithm was incorporated into a new generation of alignmentindependent mol

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18

Galaczová, Barbora. "Bezpečnost a použitelnost základních hashovacích funkcí, zejména MD-5, SHA-1 a SHA-2." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-313898.

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Title: Security and usability of standard hash functions, in particular MD-5, SHA-1 and SHA-2 Author: Galaczová Barbora Department: Department of Algebra Supervisor: Doc. RNDr. Tůma Jiří, DrSc., Department of Algebra Consultant: Ing. Budiš Petr, Ph.D. Abstract: In the present work we try to digestedly describe standard hash functions, in particular MD-5, SHA-1 and SHA-2. We describe resume of existing attacks on these hash functions. We closely focused on MD-5 collision attacks, because the other hash function collision attacks result from these. Next we describe posibilities of practical usag

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19

PLCHOVÁ, Jana. "Differential expression of tick Ixodes ricinus genes induced by blood feeding or infection: genetic analysis of ML domain containing proteins." Doctoral thesis, 2012. http://www.nusl.cz/ntk/nusl-110457.

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ML (MD-2-related lipid-recognition) domain containing proteins are recognized as immune-related molecules. They do not belong among well-studied proteins in ticks although their occurence is quite often. Generally, ML proteins are involved in innate immunity processes, lipid binding and transport. Usually, expression of tick ML domain containing proteins is induced by blood feeding. Two members of the ML protein family, ML-domain containing protein and Der-p2 allergen-like protein were isolated from Ixodes ricinus and characterized for the first time.

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20

Babych, Kateryna. "Deciphering the effects of metal-based drugs on cell signaling pathways in cancer cells." Master's thesis, 2019. http://hdl.handle.net/10400.1/13998.

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The term „cancer‟ encompasses a large group of diseases that are characterized by the development of abnormal cells, which divide, grow and spread without control in any part of the organism, spreading through blood or lymph vessels into surrounding tissues. Chemotherapy is a type of cancer treatment that uses drugs to kill cancer cells and is focused on stopping or slowing the growth of cancer cells, which divide abnormally and causes tumors. In most of the cases of chemotherapy prescription and selection of the specific drug, the more effective is a combination of two or more medicatio

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21

Burgess, Maureen Rush. "The cup of ruin and desolation seventeenth-century witchcraft in the Chesapeake /." Thesis, 2004. http://proquest.umi.com/pqdweb?index=0&did=775162921&SrchMode=1&sid=1&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1233782239&clientId=23440.

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