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Journal articles on the topic 'MDAEs'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Mukherjee, Shatavisa, Nikhil Era, and Siddhartha Roy. "Awareness Regarding Medical Device Safety among Physicians: A Knowledge, Attitude, and Practice Survey." Matrix Science Medica 8, no. 4 (2024): 88–91. http://dx.doi.org/10.4103/mtsm.mtsm_25_23.

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Abstract Background: With the huge inflow of medical devices into the healthcare market, it is imperative to monitor the device safety throughout its period of usage, with the help of a systematic continual surveillance mechanism. Although the Materiovigilance Program of India has been formally introduced since 2015, there exists a dearth of awareness regarding its existence and functioning among the major stakeholders of patient safety. Addressing this gap, the study probes the awareness regarding materiovigilance among the doctors in eastern India. Methods: A cross-sectional questionnaire-ba

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Kale, Sachin, Deepak Langade, Vaishali Thakare, Anant Patil, Sonali Das, and Arvind Vatkar. "Assessment of Knowledge, Attitude, and Practice Toward Materiovigilance Among the Health Care Workers in Mumbai: A Questionnaire-Based Study." Journal of Clinical Orthopaedics 9, no. 2 (2024): 83–87. https://doi.org/10.13107/jcorth.2024.v09i02.676.

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Introduction: Materiovigilance is an organized method for locating, obtaining, recording, and evaluating any unfavorable occurrences associated with medical devices to protect a patient’s health by preventing recurrences. Recent advancements in science and technology have led to a significant expansion in the role of medical devices in the healthcare delivery system. This questionnaire-based cross-sectional study was conducted among physicians and nurses in a teaching hospital that offers tertiary care and is part of the MvPI MDAE reporting system. Case report: Among the participants, the wors

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Binu, K. M. Sagnik Ghosh Farhan Khan Sivapriya R. Da O. Hipaya Lyngdoh Sneha P. H. Doddayya. "Assessment Of Utilization Pattern of Medical Devices and Associated Adverse Events in A Tertiary Care Teaching Hospital." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 597–603. https://doi.org/10.5281/zenodo.15336121.

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Medical devices hold significant potential for achieving self-reliance and contributing to universal healthcare goals. Although the use of medical devices benefits the patients immensely, they also carry significant potential risk<strong>. </strong>The study aimed to evaluate the utilization pattern of medical devices, categorize them based on CDSCO risk classification, and identify associated adverse events in a tertiary care teaching hospital over a six-month period. Data were collected from 100 patients across the departments of Surgery, Orthopedics, General Medicine, and Obstetrics & G

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Thilagavathi M, Thilagavathi M., Shirley Elizabeth I, Suriya G. Suriya G, Pradeep B. Pradeep B, Jothi manivannan C. Jothi manivannan C, and Sampath T. Sampath T. "Assesment of Knowledge about Materiovigilance among Pharmacy Students." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 1241–55. https://doi.org/10.35629/4494-090612411255.

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Medical device have long been essential lifesaving tools and are widely used around the world. Materiovigilance (Mv) shares the same purpose and approach as Pharmacovigilance (Pv) in ensuring patient safety, but it focuses specifically on Medical Devices associated with Adverse Events (MDAEs) and their monitoring. The MvPi in India was launched on july 6, 2015, at the Indian Pharmacopoeia Commission (IPC)The aim of the study was to assess the knowledge about materiovigilance among the pharmacy students. This descriptive, cross-sectional study utilized a questionnaire - based approach and was c

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Tyagi, Vishvanshi, Vinay Baghel, and Raj Kumari. "Knowledge, Attitude and Practices of Materiovigilance among the Medical Students and Non-Medical People: A Cross-Sectional Study." International Journal of Pharmaceutical Research and Applications 09, no. 05 (2024): 867–72. https://doi.org/10.35629/4494-0905867872.

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Background: Post-market surveillance plays a pivotal role in ensuring the quality, safety, and efficacy of medical devices, given the potential serious implications of adverse events associated with these devices. Raising awareness about materiovigilance and Medical Device-Associated Adverse Events (MDAEs) among the general population is a fundamental step in this direction. Materiovigilance programme of India (MvPI) to monitor the safety of medical devices in the country has been approved for the commencement by the Ministry of health & family welfare, Govt. of India. The MvPI was formall

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Rehman, Sana, A. Ray, and Sabitri Pandit. "Materiovigilance: Impact of awareness cum sensitization programme on healthcare professionals of a tertiary care teaching hospital in South Delhi." IP International Journal of Comprehensive and Advanced Pharmacology 7, no. 3 (2022): 146–50. http://dx.doi.org/10.18231/j.ijcaap.2022.030.

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Medical devices play a significant role in the diagnosis, monitoring, and management of different health disorders or conditions. Healthcare professionals play a significant role in the medical device adverse events reporting. However, there are only few studies regarding the awareness of medical professionals toward materiovigilance and thus, the study is to evaluate the impact of awareness cum sensitization programme towards Materiovigilance on healthcare professionals of a tertiary care teaching hospital in south Delhi. This was a cross-sectional questionnaire-based study done among the nur

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KM, Binu, H. Doddayya, Michelle Fernandes, Suman Pramanik, Maregowdagari Srikanth, and Sneha P. "Impact of Educational Intervention on Knowledge, Attitude and Practice of Materiovigilance among Healthcare Professionals: A Hospital Centered Study." Saudi Journal of Medical and Pharmaceutical Sciences 11, no. 07 (2025): 522–27. https://doi.org/10.36348/sjmps.2025.v11i07.005.

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Background: The medical devices sector in India plays a crucial role in the country's healthcare system, ranging from simple bandages to complex devices like CT scans. Materiovigilance is a system for monitoring adverse events related to medical devices. The program empowers healthcare professionals to report adverse events, ensuring patient safety and improving the overall quality of healthcare through systematic surveillance and data analysis. Objective: To assess knowledge, attitude and practice of healthcare professionals toward materiovigilance and evaluate the impact of an educational in

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Yuvaraja, M., S. Arunkumar, P. Vinodh Kumar, and L. Mary Immaculate Sheela. "Improved Grey Wolf Optimization- (IGWO-) Based Feature Selection on Multiview Features and Enhanced Multimodal-Sequential Network Intrusion Detection Approach." Wireless Communications and Mobile Computing 2023 (February 1, 2023): 1–13. http://dx.doi.org/10.1155/2023/8478457.

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The goal of the network intrusion detection system (NIDS) is to spot malicious activity in a network. It seeks to do that by examining the behavior of the traffic network. To find abnormalities, the NIDS heavily use machine learning (ML) and data mining techniques. The performance of NIDSs is significantly impacted by feature selection. This is due to the numerous characteristics that are used in anomaly identification, which take a lot of time. The time required to analyze traffic behavior and raise the accuracy level is thus influenced by the feature selection strategy. In the current work,

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Korol, L., L. Mygal, O. Burdeyna, and M. Kolesnyk. "OXIDATIVE STRESS AND RESISTANCE OF ERYTHROCYTES MEMBRANES IN PATIENTS WITH CHRONIC KIDNEY DISEASE STAGE VD DEPENDING ON MODALITY OF RENAL REPLACEMENT THERAPY." Ukrainian Journal of Nephrology and Dialysis, no. 2(50) (May 29, 2016): 29–35. http://dx.doi.org/10.31450/ukrjnd.2(50).2016.01.

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The aim of the research was to study the effect ofoxidative factors impact and modality of renal replacement therapy (BBT) on indices ofoxidative stress (OS) and resistance of erythrocytes membranes in patients with chronic kidney disease stage V(CKD VD) and anemie. Material and methods. The study involved 68 patients with CKD VD: 14 patients were treated by hemodiafiltration (HDF), 25 patients by hemodialysis (HD) and 29 patients by peritoneal dialysis (PD). The severity ofanemia was assessed according to the KDIGO (2012) criteria. The control group consisted of 30 healthy people of the

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Kolesnyk, M., L. Korol, L. Migal, O. Burdeyna, and V. Novakivskyy. "INDICATORS OF OXIDATIVE STRESS AND RESISTANCE OF ERYTHROCYTES IN PATIENTS WITH CHRONIC KIDNEY DISEASE STAGE VD DEPENDING ON MODALITY OF RENAL REPLACEMENT THERAPY." Ukrainian Journal of Nephrology and Dialysis, no. 3(47) (August 25, 2015): 57–64. http://dx.doi.org/10.31450/ukrjnd.3(47).2015.10.

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The object was to study the effect of oxidative factors and methods of renal replacement therapy (RRT) on indices of oxidative stress (OS) and resistance cells in blood in patients with chronic kidney disease stage V(CKD VD) and anemic syndrome. Material and methods. The study involved 47 patients with CKD VD: 14patients were treated by hemodiafiltration (HDF), 14 patients by hemodialysis (HD) and 19 patients by peritoneal dialysis (PD). The severity ofanemia was assessed according to the KDIGO (2012) criteria. The control group consisted of30 healthy people of the same age and sex. Alon

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Ghezelbash, Mahsa, Batool Sajad, and Shadi Hojatizadeh. "Fluorescence-Enhanced Assessments for Human Breast Cancer Cell Characterizations." Photonics 11, no. 8 (2024): 746. http://dx.doi.org/10.3390/photonics11080746.

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Even with 100% certainty of a complete cure for breast cancer (BC), there is still a long way to go toward more efficient treatment because it requires sensitive and timely detection and accurate pre/post-clinical characterizations. Despite the availability of advanced diagnostic tools, many cancer patients lack access to efficient diagnostics that are both highly reliable and affordable. The fluorescence-based optical technique aims to make another significant leap forward in improving patient safety. It offers a convenient operation that reduces healthcare costs compared to visual examinatio

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Evans, Robin J. "Latent free equivalent mDAGs." Algebraic Statistics 14, no. 1 (2023): 3–16. http://dx.doi.org/10.2140/astat.2023.14.3.

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Fuller, Brian B., Vance Harris, Caleb Parker, et al. "Contextual determinants of mass drug administration performance: Modelling fourteen years of lymphatic filariasis treatments in West Africa." PLOS Neglected Tropical Diseases 17, no. 2 (2023): e0011146. http://dx.doi.org/10.1371/journal.pntd.0011146.

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Background Effective mass drug administration (MDA) is the cornerstone in the elimination of lymphatic filariasis (LF) and a critical component in combatting all neglected tropical diseases for which preventative chemotherapy is recommended (PC-NTDs). Despite its importance, MDA coverage, however defined, is rarely investigated systematically across time and geography. Most commonly, investigations into coverage react to unsatisfactory outcomes and tend to focus on a single year and health district. Such investigations omit more macro-level influences including sociological, environmental, and

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Korol, L., N. Stepanova, O. Ablogina, and L. Migal. "ALPHA–LIPOIC ACID ANTIOXIDANT EFFICIENCY IN TREATMENT OF PERITONEAL DIALYSIS PATIENTS." Ukrainian Journal of Nephrology and Dialysis, no. 2(46) (January 12, 2015): 42–48. http://dx.doi.org/10.31450/ukrjnd.2(46).2015.07.

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The aim of the study was to evaluate the effectiveness of the antioxidant alpha–lipoic acid in peritoneal dialysis (PD) patients taking into account the state of lipid peroxidation (LPO) and antioxidant protection (AOP) before and after treatment. Patients and methods. The research revealed the intensity of oxidative processes in 20 patients treated with continuous ambulatory peritoneal dialysis (CAPD) on the basis of а–lipoic acid applied parenterally in a dose of 600 mg for 2–weeks followed by a transfer to the 6 weeks of oral reception. The intensity of oxidative processes was e

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Brazdis, Razvan-Marius, Julian E. Alecu, Daniel Marsch, et al. "Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson’s disease." Human Molecular Genetics 29, no. 7 (2020): 1180–91. http://dx.doi.org/10.1093/hmg/ddaa039.

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Abstract Parkinson’s disease (PD) is a neurodegenerative disorder characterized by protein inclusions mostly composed of aggregated forms of α-synuclein (α-Syn) and by the progressive degeneration of midbrain dopaminergic neurons (mDANs), resulting in motor symptoms. While other brain regions also undergo pathologic changes in PD, the relevance of α-Syn aggregation for the preferential loss of mDANs in PD pathology is not completely understood yet. To elucidate the mechanisms of the brain region-specific neuronal vulnerability in PD, we modeled human PD using human-induced pluripotent stem cel

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Henry, Thomas, Jian Shen, Mohammed Lahlou, et al. "Mining Data Analysis System (MDAS)." Proceedings of the Water Environment Federation 2002, no. 2 (2002): 674–88. http://dx.doi.org/10.2175/193864702785665319.

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Cordt, Almut, U. Schlegel, and F. Jerusalem. "Malignes Dopa-Entzugs-Syndrom (MDES)." Aktuelle Neurologie 13, no. 03 (1986): 99–101. http://dx.doi.org/10.1055/s-2007-1020723.

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18

Reif, Shimon, Ariel Atias, Mirit Musseri, Nickolay Koroukhov, and Regina Golan Gerstl. "Beneficial Effects of Milk-Derived Extracellular Vesicles on Liver Fibrosis Progression by Inhibiting Hepatic Stellate Cell Activation." Nutrients 14, no. 19 (2022): 4049. http://dx.doi.org/10.3390/nu14194049.

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Liver fibrosis is the consequence of various chronic liver diseases, resulting in accumulation of extracellular matrix, following the activation and proliferation of hepatic stellate cells (HSCs). Based on the milk-derived extracellular vesicles’ (MDEs’) characteristics and biological proprieties, we investigate whether MDEs may regulate fibrotic progression by inhibiting HSCs’ activation via the MDEs’ miRNA content. In order to study this question, we examined the effect of human and cow MDEs on HSCs isolated from murine livers, on activation, proliferation and their proteins’ expression. We

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Solms, Fritz, and Dawid Loubser. "Generating MDA’s platform independent model using URDAD." Knowledge-Based Systems 22, no. 3 (2009): 174–85. http://dx.doi.org/10.1016/j.knosys.2008.11.008.

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20

Al-Jarf, Reima. "Specialized Dictionary Mobile Apps for Students Learning English for Engineering, Business and Computer Science." Journal of Humanities and Education Development 4, no. 1 (2022): 01–09. http://dx.doi.org/10.22161/jhed.4.1.1.

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Use of dictionaries is an integral part of language learning and teaching. With the availability of smartphones, EFL, ESL and ESP students can access and download a variety of specialized mobile dictionaries Apps (MDAs). Specialized MDAs are of special importance for students learning English for engineering, business, and computer science purposes. They contain thousands of essential specialize technical terms covering several sub-categories within the engineering, business and computer science fields. They are a good tool for enriching the students’ specialized vocabulary and helping them le

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Özgüç Çömlek, Fatma, and Ahmet Fatih Yılmaz. "Can levels of serum uric acid and HDL cholesterol effectively predict the presence of fatty liver in children with obesity?" Anatolian Current Medical Journal 7, no. 2 (2025): 234–38. https://doi.org/10.38053/acmj.1621956.

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Aims: Our study aimed to evaluate the relationship between biochemical parameters such as high uric acid and low HDL levels and metabolic dysfunction-associated steatohepatitis (MDAS) in children with obesity. Methods: The records of 81 obese children with a body mass index above two standard deviations for their age who underwent fasting lipids, liver enzymes, uric acid level, oral glucose tolerance tests (OGTT), and abdominal ultrasounds to assess fatty liver were reviewed retrospectively. The findings from physical examinations and results from laboratory and imaging tests were documented.

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Ferreira, Francisco De Assis Costa, Elton Da Silva Leite, Luis Carlos de Freitas, and Aline Pereira das Virgens. "Potencial de krigagem em modelos digitais de elevação para o planejamento da colheita florestal." Pesquisa Florestal Brasileira 37, no. 92 (2017): 579–86. http://dx.doi.org/10.4336/2017.pfb.37.92.1492.

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Objetivou-se com este trabalho avaliar a krigagem em modelos digitais de elevação (MDEs) SRTM e ASTER como subsidio ao planejamento da colheita florestal. Foram testados os seguintes MDEs: SRTM com 30 m e com 90 m de resolução espacial (RE); ASTER com 30 m de RE; SRTM com 30 m e com 90 m krigado; ASTER 30 m krigado; e MDE padrão, obtido a partir de carta planialtimétrica. Com auxílio dos MDEs, foram gerados mapas de declividade, de acordo com as restrições operacionais de máquinas utilizadas na colheita florestal. Os MDEs foram avaliados por análise estatística descritiva e quali-quantitativa.

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Che, Kai, Maozu Guo, Chunyu Wang, Xiaoyan Liu, and Xi Chen. "Predicting MiRNA-Disease Association by Latent Feature Extraction with Positive Samples." Genes 10, no. 2 (2019): 80. http://dx.doi.org/10.3390/genes10020080.

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In discovering disease etiology and pathogenesis, the associations between MicroRNAs (miRNAs) and diseases play a critical role. Given known miRNA-disease associations (MDAs), how to uncover potential MDAs is an important problem. To solve this problem, most of the existing methods regard known MDAs as positive samples and unknown ones as negative samples, and then predict possible MDAs by iteratively revising the negative samples. However, simply viewing unknown MDAs as negative samples introduces erroneous information, which may result in poor predication performance. To avoid such defects,

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Kuzmina, Raisa P. "IMAGE OF THE BEAR IN THE STRUCTURE OF THE ZOOMORPHIC CODE OF THE EVEN CULTURE." Sovremennye issledovaniya sotsialnykh problem 14, no. 1 (2022): 81–96. http://dx.doi.org/10.12731/2077-1770-2022-14-1-81-96.

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The aim of the study is to characterize the motivating, conceptual, figurative and symbolic features of the concept BEAR in the zoomorphic code of the Even culture. Methods used in the work: the article uses the method of continuous sampling, the method of field ethnography, interviewing, as well as linguistic and cultural methods. Research results: representatives of the concept BEAR in the linguistic consciousness of the Evens are allegorical nominations formed from kinship terms, adjective, substantive and verbal lexemes. As a result of the study of the internal form of the word

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Stepanova, N., L. Korol, O. Burdeyna, and L. Snisar. "The relationship between overhydration, increased oxidative stress and peritoneal dialysis adequacy." Ukrainian Journal of Nephrology and Dialysis, no. 2(62) (February 3, 2019): 10–17. http://dx.doi.org/10.31450/ukrjnd.2(62).2019.02.

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The present study was undertaken to investigate the association of hydration status measured by bioimpedance analysis with oxidative stress biomarkers and peritoneal dialysis (PD) adequacy. Methods. It was a case-control study involved 85 PD patients from 2 dialysis centers in Ukraine. Among the examined patients, there were 56/85 (65.9%) men and 29/85 (34.1%) women. All patients had been undergoing PD for more than 3 months (median was 25.4 [14.0-49.5] months). Average age was 48.8 ± 12.5 years. Fluid compartments [extracellular water (ECW) and overhydration index (OH)] were measu

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Natalia, Stepanova, Korol Lesya, Burdeyna Olena, and Snaisar Lyudmila. "The relationship between overhydration, increased oxidative stress and peritoneal dialysis adequacy." Ukrainian Journal of Nephrology and Dialysis 2(62) (July 20, 2019): 10–17. https://doi.org/10.31450/ukrjnd.2(62).2019.02.

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The present study was undertaken to investigate the association of hydration status measured by bioimpedance analysis with oxidative stress biomarkers and peritoneal dialysis (PD) adequacy. Methods. It was a case-control study involved 85 PD patients from 2 dialysis centers in Ukraine. Among the examined patients, there were 56/85 (65.9%) men and 29/85 (34.1%) women. All patients had been undergoing PD for more than 3 months (median was 25.4 [14.0-49.5] months). Average age was 48.8 ± 12.5 years. Fluid compartments [extracellular water (ECW) and overhydration index (OH)] were measured u

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Hallemeier, Katherine. "An art of hunger: Gender and the politics of food distribution in Zakes Mda’s South Africa." Journal of Commonwealth Literature 53, no. 3 (2016): 379–93. http://dx.doi.org/10.1177/0021989416658783.

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This article examines the centrality of hunger and food in Zakes Mda’s Ways of Dying, The Heart of Redness, and The Whale Caller. While Mda’s work has been the subject of incisive readings of the politics of development in contemporary South Africa, attention to his treatment of hunger, specifically, helps to clarify the centrality of gender to Mda’s critical re-envisioning of development policies pursued by late and postapartheid governments.

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Tajirian, Margaret, Benjamin Juarez, and Tomas Martinez. "Adapting a Dental Anxiety Measure to Encourage Empathy." International Journal of Dentistry 2023 (May 22, 2023): 1–7. http://dx.doi.org/10.1155/2023/4909993.

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Introduction. The aim of this study was to improve upon the Modified Dental Anxiety Scale (MDAS) by developing the empathy-based International-Modified Dental Anxiety Scale (I-MDAS). This new measure was then utilized to compare the dental anxiety of patients cross-culturally. Methodology. This study was a descriptive cross-sectional study adapting the MDAS into the I-MDAS by adding the International scale. The study surveyed 465 participants from a dental clinic, SurveySwap, and distributed flyers. Data was collected through Qualtrics through the self-administered I-MDAS and analyzed through

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Liu, Lei, Chao Gao, Zhanliang Zhu, Xiongpeng Tang, Dongjie Zhang, and Silong Zhang. "Synchronized Structure and Teleconnection Patterns of Meteorological Drought Events over the Yangtze River Basin, China." Water 15, no. 21 (2023): 3707. http://dx.doi.org/10.3390/w15213707.

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Investigating the synchronized structure and teleconnection patterns of meteorological drought events (MDEs) contributes to elucidating drought’s evolution. In this study, the CN05.1 gridded meteorological dataset from 1961 to 2021 was utilized to calculate the 3-month standardized precipitation evapotranspiration index (SPEI-3) for each grid in the Yangtze River Basin (YRB). Based on these SPEI-3 series, the grid-based MDEs were then extracted. Subsequently, event synchronization and complex networks were employed to construct the MDE synchronized network over the YRB. This network was used t

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Desai, BC, and R. Pollock. "MDAS: heterogeneous distributed database management system." Information and Software Technology 34, no. 1 (1992): 28–42. http://dx.doi.org/10.1016/0950-5849(92)90092-4.

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Teske, Rodrigo, Elvio Giasson, and Tatiane Bagatini. "Comparação do uso de modelos digitais de elevação em mapeamento digital de solos em Dois Irmãos, RS, Brasil." Revista Brasileira de Ciência do Solo 38, no. 5 (2014): 1367–76. http://dx.doi.org/10.1590/s0100-06832014000500002.

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Os modelos digitais de elevação (MDEs) são fontes fundamentais para correlacionar a ocorrência e distribuição de solos com a paisagem pelo mapeamento digital de solos (MDS). A influência dos tipos e das resoluções dos MDEs na capacidade de predição dos modelos preditores de classes de solo ainda é pouco estudada. Neste estudo, foram avaliados e comparados os efeitos de diferentes MDEs na predição de ocorrência de unidades de mapeamento de solo (UM). Foram correlacionados 12 atributos do terreno derivados de diferentes MDEs com a ocorrência de UM. Os MDEs utilizados foram os oriundos dos projet

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Giri, Jamal, Prabhat Ranjan Pokharel, Rajesh Gyawali, and Bhushan Bhattarai. "Translation and Validation of Modified Dental Anxiety Scale: The Nepali Version." International Scholarly Research Notices 2017 (January 29, 2017): 1–5. http://dx.doi.org/10.1155/2017/5495643.

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Introduction. For proper management of anxious dental patients it is imperative to assess their levels of dental anxiety before treatment. Modified Dental Anxiety Scale (MDAS) is the most commonly used questionnaire to assess dental anxiety. But a Nepali version of MDAS is still lacking. Hence, the objective of this study was to develop a reliable and valid Nepali version of MDAS. Materials and Methods. The English version of the MDAS was translated into Nepali following a forward and backward translation process. Following pretesting and cognitive interviewing a final version of Nepali questi

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Ogawa, Mika, Teppei Sago, and Hirokazu Furukawa. "The Reliability and Validity of the Japanese Version of the Modified Dental Anxiety Scale among Dental Outpatients." Scientific World Journal 2020 (May 1, 2020): 1–6. http://dx.doi.org/10.1155/2020/8734946.

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Introduction. A careful assessment of dental anxiety is necessary for its management. The Modified Dental Anxiety Scale (MDAS) is one of the most commonly used questionnaires to measure dental anxiety in the world. The reliability and validity of the Japanese version of MDAS have been demonstrated using undergraduates and a few patients with dental anxiety. The aim of the present study was to examine the reliability and validity of the Japanese version of the MDAS using a wide range of age samples in dental clinics. Methods. A total of 275 outpatients (145 men and 130 women; 21–87 years) from

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Reif, Shimon, Yaffa Elbaum-Shiff, Nickolay Koroukhov, Itamar Shilo, Mirit Musseri, and Regina Golan-Gerstl. "Cow and Human Milk-Derived Exosomes Ameliorate Colitis in DSS Murine Model." Nutrients 12, no. 9 (2020): 2589. http://dx.doi.org/10.3390/nu12092589.

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The aim of this study was to investigate the therapeutic effect of cow and human milk derived exosomes (MDEs) on colitis. We used gavage administration of fluorescent labeled MDEs to track their localization patterns in vivo and studied their therapeutic effect on colitis in a dextran sulfate sodium (DSS)-induced colitis model. MDEs attenuated the severity of colitis induced by DSS and statistically reduced the histopathological scoring grade and shortening of the colon. Likewise, treatment with MDEs reduced the expression of interleukin 6 and tumor necrosis factor-α. Moreover, miRNAs highly e

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Ebewo, Patrick J. "Satire: A Shifting Paradigm in Zakes Mda's Dramaturgy." English Academy Review 26, no. 2 (2009): 25–37. http://dx.doi.org/10.1080/10131750903336023.

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Pellow, C. Kenneth. "Christ Symbolism in Zakes Mda’s Ways of Dying." Journal of the African Literature Association 8, no. 1 (2013): 4–23. http://dx.doi.org/10.1080/21674736.2013.11690215.

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WESOLOWSKI, KIERSTIN. "Lewis P. Rowland, MD, Receives MDAʼs Highest Honor". Neurology Today 10, № 2 (2010): 7. http://dx.doi.org/10.1097/01.nt.0000368115.83546.ef.

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Lee, Ho-Jun, and Hee-Kyung Lee. "Validation of the Korean Version of the Modified Differential Emotions Scale." Korean Association For Learner-Centered Curriculum And Instruction 25, no. 14 (2025): 195–216. https://doi.org/10.22251/jlcci.2025.25.14.195.

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Objectives The purpose of this study was to validate the modified Differential Emotions Scale (mDES; Fredrickson, 2013) into Korean, based on a functionalist perspective, to separately assess positive and negative emotions. Methods Exploratory factor analysis and confirmatory factor analysis were conducted with a sample of 525 emerging adults aged 18-34. To examine convergent validity, correlation analyses were performed with related variables, and hierarchical regression analysis was conducted to assess incremental validity. Results First, the results of the exploratory factor analysis indica

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Mpangwire, Violah, Annabella Ejiri, and Fred Kaggwa. "Technological Factors and Adoption of the Unified Identification System (UIDS) Among Government Ministries, Departments and Agencies (MDAs) In Uganda; A Quantitative Perspective." European Journal of Technology 4, no. 1 (2020): 1–15. http://dx.doi.org/10.47672/ejt.613.

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Purpose: The study sought to examine the relationship between technological factors and UID system's adoption among MDAs in Uganda. Methodology: A positivist paradigm and cross-section design were adopted with a sample of 97 MDAs generated from a population of 130 government MDAs. MDAs were stratified and randomly selected from each stratum. The heads of department and permanent secretaries/CEOs formed the unit of inquiry that was purposively selected. Self-administered questionnaire with closed-ended questions aided data collection. Pearson correlation and hierarchical multiple regressi

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Lahti, Satu, Mika Kajita, Vesa Pohjola, and Auli Suominen. "Reliability and Validity of the Modified Dental Anxiety Scale Among Children Aged 9 to 12 Years." Dentistry Journal 13, no. 6 (2025): 248. https://doi.org/10.3390/dj13060248.

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Objectives: Our aim was to study whether the Modified Dental Anxiety Scale (MDAS) is reliable and valid for use in children aged 9 to 12 years. Methods: The study population was a convenient sample of Finnish comprehensive school pupils in the third and sixth grades (N = 57 and N = 69, respectively). Dental fear and anxiety (DFA) were measured with the Finnish validated adult version of MDAS, the modified Child Fear Survey Schedule—Dental Subscale (CFSS-DS-M), and a single question. Reliability was evaluated using Cronbach’s alpha. The criterion validity of MDAS was assessed using Spearman ran

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Chishti, Faiza, Hammad Hassan, and Samir R. Qazi. "Dental Anxiety among Students of Lahore, Pakistan." Pakistan Journal of Medical and Health Sciences 15, no. 9 (2021): 2659–61. http://dx.doi.org/10.53350/pjmhs211592659.

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Objective: Current study aimed to explore the dental anxiety level among students in schools existing in Lahore. Method: This study was descriptive cross-sectional in nature. Data of 300 students was collected from three schools. Students with age of 13years or above were included in study. MDAS was used to collect data with a section of demographics. SPSS version 23.0 was used for data analysis. Results: Mean MDAS score of the sample was 14.11±4.330. The frequency of mild anxiety (MDAS <11) was 21.3%, moderate to severe anxiety (MDAS 11 to 18) was 62.7%, and dental phobia (MDAS 19 to 25) w

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Chong, Adam J. "Exceptionality and derived environment effects: a comparison of Korean and Turkish." Phonology 36, no. 4 (2019): 543–72. http://dx.doi.org/10.1017/s0952675719000289.

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Morphologically derived environment effects (MDEEs) are well-known examples where phonotactic patterns in the lexicon mismatch with what is allowed at morphological boundaries – alternations. Analyses of MDEEs usually assume that the alternation is morphologically general, and that the sequences ‘repaired’ across morpheme boundaries are phonotactically well-formed in the lexicon. This paper examines the phonotactic patterns in the lexicon of two languages with MDEEs: Korean palatalisation and Turkish velar deletion. I show that Korean heteromorphemic sequences that undergo palatalisation are u

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Reif, Shimon, Liron Birimberg-Schwartz, Myriam Grunewald, et al. "The Effect of Milk-Derived Extracellular Vesicles on Intestinal Epithelial Cell Proliferation." International Journal of Molecular Sciences 25, no. 24 (2024): 13519. https://doi.org/10.3390/ijms252413519.

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Inflammatory bowel disease (IBD) is a chronic, relapsing inflammation disorder of the gastrointestinal tract characterized by disrupted intestinal epithelial barrier function. Despite advances in treatment, including biological agents, achieving sustained remission remains challenging for many patients with IBD. This highlights the urgent need for novel therapeutic strategies. Milk-derived extracellular vesicles (MDEs) have emerged as a promising therapeutic option. In this study, we isolated and characterized MDEs and evaluated their effects on the function of intestinal epithelial cells (IEC

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Fu, Xiao-Hong, Jian-Ping Li, Xue-Ying Li та ін. "M2-Macrophage-Derived Exosomes Promote Meningioma Progression through TGF-β Signaling Pathway". Journal of Immunology Research 2022 (20 травня 2022): 1–20. http://dx.doi.org/10.1155/2022/8326591.

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Tumor-associated macrophages (TAMs) have been shown to be an essential component of the tumor microenvironment and facilitate the proliferation and invasion of a variety of malignancies. However, the contribution of TAMs to meningioma progression has not been characterized in detail. In this study, we aimed to discover a novel regulatory pathway by which exosome-mediated M2-polarized macrophages participate in meningioma tumorigenesis and progression. Methods. First, the distribution and functional phenotype of macrophages in meningioma tissues were assessed by immunohistochemistry. Macrophage

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Wijenayake, Sanoji, Shafinaz Eisha, Zoya Tawhidi, et al. "Comparison of methods for pre-processing, exosome isolation, and RNA extraction in unpasteurized bovine and human milk." PLOS ONE 16, no. 9 (2021): e0257633. http://dx.doi.org/10.1371/journal.pone.0257633.

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Milk is a highly complex, heterogeneous biological fluid that contains non-nutritive, bioactive extracellular vesicles called exosomes. Characterization of milk-derived exosomes (MDEs) is challenging due to the lack of standardized methods that are currently being used for milk pre-processing, storage, and exosome isolation. In this study, we tested: 1) three pre-processing methods to remove cream, fat, cellular debris, and casein proteins from bovine milk to determine whether pre-processing of whole milk prior to long-term storage improves MDE isolations, 2) the suitability of two standard ex

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Park, Eun Gyung, Yun Ju Lee, Jae-Won Huh, et al. "Identification of microRNAs Derived from Transposable Elements in the Macaca mulatta (Rhesus Monkey) Genome." Genes 14, no. 11 (2023): 1984. http://dx.doi.org/10.3390/genes14111984.

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Transposable elements (TEs) are mobile DNA entities that can move within the host genome. Over long periods of evolutionary time, TEs are typically silenced via the accumulation of mutations in the genome, ultimately resulting in their immobilization. However, they still play an important role in the host genome by acting as regulatory elements. They influence host transcription in various ways, one of which as the origin of the generation of microRNAs (miRNAs), which are so-called miRNAs derived from TEs (MDTEs). miRNAs are small non-coding RNAs that are involved in many biological processes

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Jääskeläinen, Anssi, and Osmo Palonen. "Revising the quality management plan behind MDAS." Archiving Conference 9, no. 1 (2012): 255–59. http://dx.doi.org/10.2352/issn.2168-3204.2012.9.1.art00056.

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Yang, Fan, Zixiang Zhu, Huanan Liu, et al. "Evaluation of Antibody Response in Sows after Vaccination with Senecavirus A Vaccine and the Effect of Maternal Antibody Transfer on Antibody Dynamics in Offspring." Vaccines 9, no. 10 (2021): 1066. http://dx.doi.org/10.3390/vaccines9101066.

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Senecavirus A (SVA) is a newly porcine virus that has been detected in many countries since its first detection in pigs in Canada in 2007, and it remains endemic in many countries in Asia and America, which has become a substantial problem for the pig industry. Vaccination is a potentially effective strategy for the prevention and control of SVA infection. Our lab has developed a SVA vaccine candidate previously. In this study, the antibody response to the prepared vaccine in sows and their offspring was evaluated. Vaccination of sows with inactivated SVA vaccines during pregnancy elicited SVA

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Silveira, Ricardo Michael Pinheiro, and Claudinei Taborda Da Silveira. "ANÁLISE COMPARATIVA ENTRE MODELOS DIGITAIS DE ELEVAÇÃO COM DISTINTAS CARACTERÍSTICAS DE PROCESSAMENTO E AQUISIÇÃO." Boletim de Geografia 33 (May 14, 2016): 106. http://dx.doi.org/10.4025/bolgeogr.v33i0.31930.

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A utilização cada vez mais abrangente de Modelos Digitais de Elevação (MDEs) denota a necessidade do reconhecimento das limitações e potencialidades da modelagem e seus efeitos nos produtos derivados. Nessa perspectiva, o presente trabalho tem como objetivo analisar, por cálculos estatísticos comparativos, matriz de confusão e técnicas de geoprocessamento, as diferenças inerentes entre MDEs com distintas características de aquisição na área de estudo que compreende a porção central da Serra do Mar no estado do Paraná, Brasil. Primeiramente foram avaliados os efeitos da variação do tamanho de c

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Humphris, Gerry M., and P. Hull. "Do Dental Anxiety Questionnaires Raise Anxiety in Dentally Anxious Adult Patients? A Two-Wave Panel Study." Primary Dental Care os14, no. 1 (2007): 7–11. http://dx.doi.org/10.1308/135576107779398165.

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Objective To test whether or not dentally anxious patients attending the dentist for an appointment become more anxious when completing a dental anxiety questionnaire. Basic research design Patients were initially screened to include only those who were dentally anxious. A pre- and post-test was planned with the completion of the Modified Dental Anxiety Scale (MDAS) questionnaire as the intervention. Clinical setting Two dental access centres in the North West of England. Participants Initially, 583 patients were screened. Of these, 182 (31%) were found to be dentally anxious and were recruite

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