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Journal articles on the topic 'MDR isolates'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Subramanian, Nivetha, Mangaiyarkarasi Thiyagarajan, Udhayasankar Ranganathan, Sunil S. Shivekar, and R. Gopal. "Colistin Susceptibility and Plasmid Mediated mcr-1 Gene Prevalance among Multi Drug Resistant Clinical Isolates of Escherichia coli, Kebsiella pneumoniae and Pseudomonas aeruginosa - A Hospital Based Cross Sectional Study." Journal of Medical Sciences and Health 10, no. 3 (2025): 294–300. https://doi.org/10.46347/jmsh.v10.i3.24.248.

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Introduction: The treatment options for multi drug resistant (MDR) and extensively drug resistant (XDR) Gram negative bacterial infections are limited. Colistin based combination therapy remains the last option for such infections. The emerging resistance to colistin, especially the transferrable mcr-1 gene mediated resistance poses a global threat. Objectives: This study aims to determine the colistin susceptibility among the multi drug resistant (MDR) clinical isolates of Escherichia coli, Kebsiella pneumoniae and Pseudomonas aeruginosa and also to determine the prevalence of mcr-1 gene in t

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Otokunefor, Kome, Victor Ogechi Osogho, and Chijindu Precious Nwankwo. "Escherichia coli as Possible Agents of Spread of Multidrug Resistance in Port Harcourt, Rivers State." Annals of Science and Technology 4, no. 1 (2019): 16–21. http://dx.doi.org/10.2478/ast-2019-0002.

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AbstractMultidrug resistance (MDR) continues to be a growing global issue. The problem of MDR is fuelled in part by the spread of the genes encoding resistance horizontally which is linked particularly to conjugation involving plasmids. Studies have demonstrated the presence of plasmids in drug resistant isolates, few have shown a link between these plasmids and drug resistance via plasmid curing especially in our locale. This study set out to explore this link inEscherichia coliisolates from Port Harcourt, Nigeria. Plasmid curing was done on a selection of clinical and non-clinical bacteria u

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Keen, Edward F., Clinton K. Murray, Brian J. Robinson, Duane R. Hospenthal, Edgie-Mark A. Co, and Wade K. Aldous. "Changes in the Incidences of Multidrug-Resistant and Extensively Drug-Resistant Organisms Isolated in a Military Medical Center." Infection Control & Hospital Epidemiology 31, no. 7 (2010): 728–32. http://dx.doi.org/10.1086/653617.

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Background.Multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa have emerged as the causes of nosocomial infections in critically ill patients.Objective.To characterize the incidence of these MDR bacteria over time in the military healthcare system, comparing isolates recovered from overseas combat casualties with isolates recovered from local military and civilian patients.Methods.Retrospective electronic records review of culture and/or susceptibility testing results of patients admitted to a military level I trauma center in San Antonio, Texas, during the period from

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Rosana, Yeva, Lina Herliyana, Grady Krisandi, and Erike Anggraini Suwarsono. "Profile of multidrug-resistant bacteria causing urinary tract infections in inpatients and outpatients in Jakarta and Tangerang." Universa Medicina 42, no. 3 (2023): 303–13. http://dx.doi.org/10.18051/univmed.2023.v42.303-313.

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Background Urinary tract infections (UTIs) caused by bacteria occupy the second highest rank of common infectious diseases in the world. Empirical use of antibiotics may give rise to multidrug-resistant (MDR) bacteria because of irrational prescription. Choice of antibiotics to treat UTIs is limited because of MDR bacteria. Thus, this study was conducted to investigate the bacterial antibiotic susceptibility patterns in inpatients and outpatients in Jakarta and Tangerang. Methods Bacterial isolates were obtained from midstream urine specimens from 43 inpatients and 43 outpatients with UTIs in

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Naba, Kumar Deka, Choudhury Mridusmita, Malakar Dipika, Borah Probodh, and Jyoti Handique Pratap. "Antibiogram of Borderline Oxacillin-Resistant Staphylococcus aureus (BORSA) and Modified Staphylococcus aureus (MODSA) Isolates From Human and Animals in Assam, India." Indian Journal of Science and Technology 18, no. 2 (2025): 168–76. https://doi.org/10.17485/IJST/v18i2.3733.

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<strong>Objectives:</strong> Detection of borderline oxacillin-resistant Staphylococcus aureus (BORSA) and modified Staphylococcus aureus (MODSA) strains with clinical significance are rare events. They have clinical, community, and livestock-associated significance. We aimed to screen these strains and evaluate the antibiogram through an array of antibiotics in Assam, a northeastern state of India. <strong>Method:</strong> S. aureus was confirmed biochemically and at the molecular level. Oxacillin and cefoxitin resistance were screened through the disc diffusion test. Hyperprod

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Wongsrichai, Supaporn, Patchara Phuektes, and Suphattra Jittimanee. "Multidrug-resistance and mobile colistin resistance (mcr) genes of Salmonella isolates from pork in Thailand during 2014-2017: comparison between two different types of slaughterhouses and retails." Veterinary Integrative Sciences 19, no. 3 (2021): 333–48. http://dx.doi.org/10.12982/vis.2021.029.

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Food-producing animals are the major reservoir for Salmonella infections in humans. Salmonella contamination and spread of antimicrobial resistance genes can occur during the production chain of animal products. The aims of this study were to investigate antimicrobial resistance patterns and compare the proportions of multidrug resistance and the presence of mobile colistin resistance (mcr) genes, mcr-1, mcr-2 and mcr-3, among Salmonella isolates which were recovered from pork at two different standard practice slaughterhouses and retails during 2014-2017 in Thailand. Salmonella isolates recov

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Kansak, Nilgün, Sebahat Aksaray, Müge Aslan, Rıza Adaleti, and Nevriye Gönüllü. "Detection of colistin resistance among multidrug-resistant Klebsiella pneumoniae and Escherichia coli clinical isolates in Turkey." Acta Microbiologica et Immunologica Hungarica 68, no. 2 (2021): 99–106. http://dx.doi.org/10.1556/030.2021.01328.

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AbstractIn this study investigation of plasmid-mediated mcr 1-5 resistance genes was performed among multidrug-resistant (MDR) colistin sensitive and resistant Klebsiella pneumoniae and Escherichia coli strains isolated in our laboratory. We aimed to evaluate automated system (Vitek-2), broth microdilution (BMD) reference method and chromogenic media performance. Totally 94 MDR K. pneumoniae and six E. coli isolates were included in the study. CHROMID® Colistin R agar (COLR) (bioMerieux, France) was used to determine the colistin resistance by chromogenic method. Standard PCR amplification was

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Munim, Md Adnan, Shuvo Chandra Das, Md Murad Hossain, Ithmam Hami, Mridul Gope Topu, and Shipan Das Gupta. "Multi-drug resistant (MDR) Gram-negative pathogenic bacteria isolated from poultry in the Noakhali region of Bangladesh." PLOS ONE 19, no. 8 (2024): e0292638. http://dx.doi.org/10.1371/journal.pone.0292638.

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Rapidly increasing antibiotic-resistant bacterial strains in Bangladesh’s food and farm animals stem from the excessive and inappropriate use of antibiotics. To assess the prevalence of multi-drug resistant (MDR) Gram-negative bacteria in poultry chicks, we sought to isolate and identify strains carrying antimicrobial resistance genes. Isolation and identification involved biochemical tests, 16S rRNA sequencing, and PCR screening of species-specific genes. MDR patterns were evaluated using CLSI guidelines with seventeen antibiotics across twelve classes. Targeted gene sequences were amplified

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Kiley, John L., Dana M. Blyth, Dana M. Blyth, et al. "543. Biocide Resistance Genes in Klebsiella spp. Infections from Trauma Patients in Iraq and Afghanistan." Open Forum Infectious Diseases 6, Supplement_2 (2019): S259. http://dx.doi.org/10.1093/ofid/ofz360.612.

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Abstract Background Biocides play an integral role in infection control. Paralleling concern about rising incidence of multidrug-resistant (MDR) organisms is a concern for resistance to biocides. In small studies, several genes involved in the production of efflux pump proteins have been identified as markers of biocide resistance in Klebsiella spp., namely cepA, qacA, qacE, qac∆E, and acrA. This study aimed to analyze the Klebsiella spp. isolates of a previously defined military trauma group with a high incidence of MDR organisms for the presence of these genes and their correlation with othe

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Flament-Simon, Saskia-Camille, Marie-Hélène Nicolas-Chanoine, Vanesa García, et al. "Clonal Structure, Virulence Factor-encoding Genes and Antibiotic Resistance of Escherichia coli, Causing Urinary Tract Infections and Other Extraintestinal Infections in Humans in Spain and France during 2016." Antibiotics 9, no. 4 (2020): 161. http://dx.doi.org/10.3390/antibiotics9040161.

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Escherichia coli is the main pathogen responsible for extraintestinal infections. A total of 196 clinical E. coli consecutively isolated during 2016 in Spain (100 from Lucus Augusti hospital in Lugo) and France (96 from Beaujon hospital in Clichy) were characterized. Phylogroups, clonotypes, sequence types (STs), O:H serotypes, virulence factor (VF)-encoding genes and antibiotic resistance were determined. Approximately 10% of the infections were caused by ST131 isolates in both hospitals and approximately 60% of these infections were caused by isolates belonging to only 10 STs (ST10, ST12, ST

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M. O, Eghieye,, Ngwai Y.B, Nkene I.H, Tama S.C, Bolarinwa, O.F, and Abimiku, R. H. "Antibiotic Susceptibility Pattern of Urinary Quinolone-resistant Escherichia coli from Selected Patients Admitted at General Hospitals in Abuja Municipal, Nigeria." International Journal of Pathogen Research 13, no. 6 (2024): 137–44. https://doi.org/10.9734/ijpr/2024/v13i6328.

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Aims: The aim of this study was to determine the antimicrobial susceptibility pattern, of urinary quinolone-resistant Escherichia coli from selected General Hospitals in Abuja Municipal, Nigeria. Study Design: Cross sectional study. Place and Duration of Study: Department of Microbiology, Nasarawa State University, Keffi, between November 2023 and October 2024. Methodology: A total of 200 samples were collected from urine of patients. Escherichia coli was isolated from the samples using standard cultural and microbiological methods. Antibiotic susceptibility testing and minimum inhibitory conc

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Mitsuwan, Watcharapong, Ratchadaporn Boripun, Phirabhat Saengsawang, et al. "Multidrug Resistance, Biofilm-Forming Ability, and Molecular Characterization of Vibrio Species Isolated from Foods in Thailand." Antibiotics 14, no. 3 (2025): 235. https://doi.org/10.3390/antibiotics14030235.

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Background: Vibrio species are common foodborne pathogens that cause gastrointestinal tract inflammation. Multidrug resistance (MDR) in Vibrio spp. is a global health concern, especially in aquaculture systems and food chain systems. This study aimed to detect Vibrio contamination in food collected from 14 markets in Nakhon Si Thammarat, Thailand, and determine their antibiotic susceptibility. Methods: One hundred and thirty-six food samples were investigated for Vibrio contamination. All isolates were tested for antibiogram and biofilm-forming ability. Moreover, the ceftazidime or cefotaxime

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Sah, Bhola Shankar, Manita Aryal, Dipak Bhargava, and Amrullah Siddique. "Drug Resistance Pattern of Bacterial Pathogens of Enterobacteriaceae Family." Tribhuvan University Journal of Microbiology 4 (November 16, 2018): 15–22. http://dx.doi.org/10.3126/tujm.v4i0.21672.

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Objectives: This study was done to determine the drug resistance pattern and Extended Spectrum β-Lactamase (ESBL) in bacterial isolates of Enterobacteriaceae family from different clinical specimens.Methods: The isolates were identified by conventional culture techniques and subjected to antimicrobial susceptibility testing by modified Kirby Bauer disk diffusion methods and ESBL detection by combined disk method.Results: Of the total 1602 sample processed 200 (12.5%) bacteria of Enterobacteriaceae family were isolated and 85.5% of them were multidrug resistant. Of the total Enterobacteriaceae

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Ford, Mary, Kathryn Lago, Quratulain Kizilbash, and Adriana Vasquez. "801. Emergence of Multi-Drug Resistance Tuberculosis During the Treatment Course of Pan-Susceptible TB: A Case Series." Open Forum Infectious Diseases 5, suppl_1 (2018): S287. http://dx.doi.org/10.1093/ofid/ofy210.808.

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Abstract Background Successful treatment of tuberculosis (TB) requires monitoring for clinical, radiographic, and microbiologic improvement. Even after negative cultures are obtained, there should be continued monitoring of sputa. If cultures become positive during treatment of drug susceptible TB (DS-TB), there should be concern for multi-drug-resistant tuberculosis (MDR-TB). We present two cases diagnosed with DS-TB who developed MDR-TB during treatment. Case Report: Case 1 is a 33-year-old male who was incarcerated in Peru. During incarceration in 2008, three of his cellmates had MDR-TB and

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Mushi, Martha F., Stephen E. Mshana, Can Imirzalioglu, and Freddie Bwanga. "Carbapenemase Genes among Multidrug Resistant Gram Negative Clinical Isolates from a Tertiary Hospital in Mwanza, Tanzania." BioMed Research International 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/303104.

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The burden of antimicrobial resistance (AMR) is rapidly growing across antibiotic classes, with increased detection of isolates resistant to carbapenems. Data on the prevalence of carbapenem resistance in developing countries is limited; therefore, in this study, we determined the prevalence of carbapenemase genes among multidrug resistant gram negative bacteria (MDR-GNB) isolated from clinical specimens in a tertiary hospital in Mwanza, Tanzania. A total of 227 MDR-GNB isolates were analyzed for carbapenem resistance genes. For each isolate, five different PCR assays were performed, allowing

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Chan, Wing Yu, Stefan Hobi, Andrew Ferguson, and Ibrahim Elsohaby. "Canine Pyoderma and Otitis Externa: A Retrospective Analysis of Multidrug-Resistant Bacterial Carriage in Hong Kong." Antibiotics 14, no. 7 (2025): 685. https://doi.org/10.3390/antibiotics14070685.

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Background: Canine pyoderma and otitis externa are prevalent bacterial skin infections in veterinary practice, frequently complicated by the emergence of multidrug-resistant (MDR) pathogens. Objectives: To investigate the frequency, antimicrobial resistance (AMR) profiles, and frequency of MDR bacterial isolates from dogs with pyoderma or otitis externa in Hong Kong. Methods: A retrospective study of bacterial isolates from 215 clinical samples collected from dogs presenting with pyoderma (n = 63) or otitis externa (n = 152) at veterinary clinics across Hong Kong between 2018 and 2022. Bacteri

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Ihator, F., and B,O, Ejechi. "Spread of Multi-drug Resistant Aerosolised Salmonella sp and Escherichiacoli from Dumpsites in Built Environment of Abraka Town, Nigeria." Nigerian Journal of Science and Environment 21, no. 3 (2024): 135–49. http://dx.doi.org/10.61448/njse213232.

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Waste dumpsites are known to be hot spots for the development of multi-drug resistant (MDR) pathogenic microorganisms, which can be dispersed via aerosols. The dispersal of MDR Salmonella sp and E. coli in dumpsite-infested neighbourhoods of Abraka, a university town, was therefore investigated. Eosine Methylene Blue and Bismuth Sulphite agar plates were used to isolate airborne E. coli and Salmonella sp, respectively using settling plate technique. Air sampling was carried out at 3 neighbourhood dumpsites and at intervals of 50m up to 200m away from the dumpsites along the cardinal directions

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Lee, Kyungwon, Dongeun Yong, Jong Hwa Yum, et al. "Emergence of Multidrug-Resistant Salmonella enterica Serovar Typhi in Korea." Antimicrobial Agents and Chemotherapy 48, no. 11 (2004): 4130–35. http://dx.doi.org/10.1128/aac.48.11.4130-4135.2004.

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ABSTRACT A chloramphenicol-resistant strain of Salmonella enterica serovar Typhi was first noted in Korea in 1992, when a resistant isolate was detected in a returned traveler. Continued isolation of multidrug-resistant (MDR) strains thereafter in other settings prompted a retrospective analysis of laboratory records and phenotypic and genotypic analyses of 12 chloramphenicol-resistant isolates. Among these, one isolate was resistant only to chloramphenicol, and the other isolates were also resistant to ampicillin and co-trimoxazole. MDR was transferred by conjugation from 9 of the 11 isolates

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Sharma, Mruganxi Harshad, Suriya Palamae, Mingkwan Yingkajorn, Soottawat Benjakul, Avtar Singh, and Jirayu Buatong. "Multidrug-Resistance of Vibrio Species in Bivalve Mollusks from Southern Thailand: Isolation, Identification, Pathogenicity, and Their Sensitivity toward Chitooligosaccharide-Epigallocatechin-3-Gallate Conjugate." Foods 13, no. 15 (2024): 2375. http://dx.doi.org/10.3390/foods13152375.

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Vibrio spp. is a Gram-negative bacteria known for its ability to cause foodborne infection in association with eating raw or undercooked seafood. The majority of these foodborne illnesses are caused by mollusks, especially bivalves. Thus, the prevalence of Vibrio spp. in blood clams (Tegillarca granosa), baby clams (Paphia undulata), and Asian green mussels (Perna viridis) from South Thailand was determined. A total of 649 Vibrio spp. isolates were subjected to pathogenicity analysis on blood agar plates, among which 21 isolates from blood clams (15 isolates), baby clams (2 isolates), and gree

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Tam, Vincent H., Kai-Tai Chang, Kamilia Abdelraouf, et al. "Prevalence, Resistance Mechanisms, and Susceptibility of Multidrug-Resistant Bloodstream Isolates of Pseudomonas aeruginosa." Antimicrobial Agents and Chemotherapy 54, no. 3 (2010): 1160–64. http://dx.doi.org/10.1128/aac.01446-09.

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ABSTRACT Pseudomonas aeruginosa is an important pathogen commonly implicated in nosocomial infections. The occurrence of multidrug-resistant (MDR) P. aeruginosa strains is increasing worldwide and limiting our therapeutic options. The MDR phenotype can be mediated by a variety of resistance mechanisms, and the corresponding relative biofitness is not well established. We examined the prevalence, resistance mechanisms, and susceptibility of MDR P. aeruginosa isolates (resistant to ≥3 classes of antipseudomonal agents [penicillins/cephalosporins, carbapenems, quinolones, and aminoglycosides]) ob

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Journal, Baghdad Science. "Production and Extraction of Siderophores-Catecholate- from -MDR-Acinetobacter baumannii." Baghdad Science Journal 14, no. 2 (2017): 356–62. http://dx.doi.org/10.21123/bsj.14.2.356-362.

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Siderophores are low molecular weight organic compounds produced by microorganisms growing under low iron concentration.In this study we describe the detection, production and extraction of siderophores secreted by Acinetobacter baumannii (Multiple-drug resistant ) pathogens. One hundered twenty Gram –negative non lactose fermenter bacilli isolates have been collected from three hospitals at Baghdad city over three months. Primary identification of these isolates is performed by standard diagnostic methods (biochemical tests and API 20 NE); 19 clinical isolates of A. baumannii are cultured on

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Deka, Naba Kumar, Mridusmita Choudhury, Dipika Malakar, Probodh Borah, and Pratap Jyoti Handique. "Antibiogram of Borderline Oxacillin-Resistant Staphylococcus aureus (BORSA) and Modified Staphylococcus aureus (MODSA) Isolates From Human and Animals in Assam, India." Indian Journal Of Science And Technology 18, no. 2 (2025): 168–76. https://doi.org/10.17485/ijst/v18i2.3733.

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Objectives: Detection of borderline oxacillin-resistant Staphylococcus aureus (BORSA) and modified Staphylococcus aureus (MODSA) strains with clinical significance are rare events. They have clinical, community, and livestock-associated significance. We aimed to screen these strains and evaluate the antibiogram through an array of antibiotics in Assam, a northeastern state of India. Method: S. aureus was confirmed biochemically and at the molecular level. Oxacillin and cefoxitin resistance were screened through the disc diffusion test. Hyperproduction of β-lactamase was screened using ticarcil

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Ng, Kamela Charmaine S., and Windell L. Rivera. "Antimicrobial Resistance of Salmonella enterica Isolates from Tonsil and Jejunum with Lymph Node Tissues of Slaughtered Swine in Metro Manila, Philippines." ISRN Microbiology 2014 (March 4, 2014): 1–9. http://dx.doi.org/10.1155/2014/364265.

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Due to frequent antibiotic exposure, swine is now recognized as potential risk in disseminating drug-resistant Salmonella enterica strains. This study thus subjected 20 randomly selected S. enterica isolates from tonsil and jejunum with lymph node (JLN) tissues of swine slaughtered in Metro Manila, Philippines, to VITEK 2 antimicrobial susceptibility testing (AST). The test revealed all 20 isolates had resistance to at least one antimicrobial agent, in which highest occurrence of resistance was to amikacin (100%), cefazolin (100%), cefuroxime (100%), cefuroxime axetil (100%), cefoxitin (100%),

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SULAIMAN, Mamunu Abdulkadir, J. Kawuni, A. Madika, et al. "IN VITRO SCREENING OF COLIPHAGE EFFICACY AGAINST MULTIDRUG DRUG RESISTANT CLINICAL ISOLATES OF ESCHERICHIA COLI." FUDMA JOURNAL OF SCIENCES 4, no. 3 (2020): 464–69. http://dx.doi.org/10.33003/fjs-2020-0403-366.

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The incidence of multi-drug resistance (MDR) in bacteria has become a major problem in this era of modern medicine, making it necessary to look for other options that can be used to treat the infections caused by the MDR bacteria. Scientifically, one of the therapies that is now looking promising, is application of phage therapy. This research work was designed to determine the efficacy of coliphages isolated from sewage, against MDR clinical isolates of E. coli. Ten (10) clinical isolates were subjected to both microbiological conventional and PCR techniques for confirmation, thereafter, the

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Li, Changan, Xiulei Gu, Liping Zhang, et al. "The Occurrence and Genomic Characteristics of mcr-1-Harboring Salmonella from Retail Meats and Eggs in Qingdao, China." Foods 11, no. 23 (2022): 3854. http://dx.doi.org/10.3390/foods11233854.

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Salmonella are widely distributed foodborne pathogens and are often associated with food animal products. Colistin resistance mediated by mcr-1 is an increasing threat; however, data on the characteristics of mcr-1-harboring Salmonella among retail foods are still lacking. In this study, retail meats from 24 supermarkets and eggs from nine markets in Qingdao city were investigated to determine the presence and genomic characteristics of mcr-1-harboring Salmonella. We found the retail meats and eggs were highly contaminated by Salmonella, with detection rates of 17.5% (31/177) and 12.3% (16/130

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Masoud, Salwa Mahmoud, Rehab Mahmoud Abd El-Baky, Sherine A. Aly, and Reham Ali Ibrahem. "Co-Existence of Certain ESBLs, MBLs and Plasmid Mediated Quinolone Resistance Genes among MDR E. coli Isolated from Different Clinical Specimens in Egypt." Antibiotics 10, no. 7 (2021): 835. http://dx.doi.org/10.3390/antibiotics10070835.

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The emergence of multi-drug resistant (MDR) strains and even pan drug resistant (PDR) strains is alarming. In this study, we studied the resistance pattern of E. coli pathogens recovered from patients with different infections in different hospitals in Minia, Egypt and the co-existence of different resistance determinants. E. coli was the most prevalent among patients suffering from urinary tract infections (62%), while they were the least isolated from eye infections (10%). High prevalence of MDR isolates was found (73%) associated with high ESBLs and MBLs production (89.4% and 64.8%, respect

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Natrajan Arumugam, Shri, Akarsh Chickamagalur Rudraradhya, Sathish Sadagopan, Sunilkumar Sukumaran, Ganesh Sambasivam, and Nachimuthu Ramesh. "Analysis of Susceptibility Patterns of Pseudomonas aeruginosa and Isolation, Characterization of Lytic Bacteriophages Targeting Multi Drug Resistant Pseudomonas aeruginosa." Biomedical and Pharmacology Journal 11, no. 2 (2018): 1105–17. http://dx.doi.org/10.13005/bpj/1471.

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Pseudomonas aeruginosa is known to be a major cause of Hospital Acquired Infections leading to high mortality in immune-compromised patients. Due to precipitous rise in antibiotic resistance, bacteriophages are significant alternative therapeutic approach for treatment and to combat resistance development. Objective of the current study was to identify MDR Pseudomonas aeruginosa from clinical isolates and to isolate bacteriophages from sewage samples against these MDR Pseudomonas aeruginosa strains. One hundred and forty-four Pseudomonas isolates were tested for their susceptibility pattern wi

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Satchasataporn, Khomson, Duangdaow Khunbutsri, Peechanika Chopjitt, Samak Sutjarit, Wanida Pan-utai, and Nattakan Meekhanon. "Antimicrobial Resistance Patterns of ESBL-Producing Escherichia coli in Dogs from Thailand: Evaluation of Algal Extracts as Novel Antimicrobial Agents." Antibiotics 14, no. 4 (2025): 377. https://doi.org/10.3390/antibiotics14040377.

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Background/Objectives: Multidrug-resistant (MDR) bacteria, including extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli, in companion animals pose a growing public health concern due to the close interactions between pets and humans. This study aimed to investigate antimicrobial resistance patterns and the prevalence of ESBL-producing E. coli isolated from healthy dogs in Thailand, as well as the potential of algal extracts obtained through ethanol extraction and enzymatic hydrolysis as alternative antimicrobial agents against these drug-resistant organisms. Methods: Antimicrob

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Shetru, Manjunath Nandihalli, Maribasappa Karched, Dayanand Agsar, and Rangaswamy B E. "In vitro lytic efficacy of bacteriophages against multidrug-resistant pathogenic bacterial species isolated from pyogenic skin infections." Indian Journal of Microbiology Research 9, no. 1 (2022): 14–23. http://dx.doi.org/10.18231/j.ijmr.2022.003.

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Bacterial multidrug resistance has worsened the situation by adding to economic burden but also poses a greater risk of patient death. The aim of the study was to characterize the multidrug resistance (MDR) properties of the bacterial isolates from skin infections and then to isolate and evaluate lytic efficacy of bacteriophages against the pathogenic bacteria. Antimicrobial susceptibilities of the isolates (n=84) from pyogenic skin infections against 14 antibiotics was studied using CLSI guidelines. Phylogenetic analyses of the MDR strains from each species was performed. Lytic efficacy of th

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Basuony, Mohamed E., Hosni A. M. Hussien, Elsayed K. Bakhiet, Walid H. Kilany, Nermeen M. Abu-Elala, and Ahmed Ali. "In-vivo characterization of multidrug-resistant Salmonella enterica Serovar Enteritidis (SE) recovered from fertile eggs and baby chicks." German Journal of Microbiology 2, no. 3 (2022): 24–33. http://dx.doi.org/10.51585/gjm.2022.3.0019.

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The present study was conducted to isolate and characterize Salmonella spp. from hatching eggs and baby chicks. Additionally, the pathogenicity of the isolated Salmonella strains was assessed in one-day-old specific pathogen-free (SPF) chicks in-vivo. Samples from sick baby chicks from 14 broiler chicken farms (including 1 duck farm) and 150 egg batches from three breeder chicken farms were collected from 4 different governorates. Phenotypically identified Salmonella isolates were confirmed using species-specific multiplex-PCR targeting the inv -A gene for Salmonella genus, E -1 gene for Salmo

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Voronina, Olga L., Марина S. Kunda, Natalia N. Ryzhova, et al. "Genomic features of resistant <i>Klebsiella pneumonia</i>, isolated from the bloodstream and cerebrospinal fluid of pediatric hospital patients." Journal of microbiology, epidemiology and immunobiology 100, no. 6 (2024): 399–409. http://dx.doi.org/10.36233/0372-9311-430.

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Introduction. Carbapenemase-producing Klebsiella pneumoniae (CP-Kp), which are international high-risk clones, have become a problem of utmost importance. CP-Kps, adapting to the hospital environment, evolve into convergent pathotypes. Such variants combine traits of two genetic lineages: multidrug resistant (MDR) and hypervirulent. The pathotypes, along with MDR K. pneumoniae, pose an exceptional threat to young patients during systemic infection. The objective of this study is the detailed molecular genetic analysis of MDR isolates of K. pneumoniae detected during the monitoring of res

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Alhabib, Ibrahim, and Nasreldin Elhadi. "Antimicrobial resistance pattern of Escherichia coli isolated from imported frozen shrimp in Saudi Arabia." PeerJ 12 (December 20, 2024): e18689. https://doi.org/10.7717/peerj.18689.

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Contamination of seafood products with multi-drug-resistant (MDR) bacteria is considered to be a potential source for the spread of MDR bacteria in communities. However, little is known about the extent of the contamination of seafood, in particular shrimp, with MDR bacteria in Saudi Arabia. In this study, imported frozen shrimp in retail markets were examined for the antimicrobial susceptibility patterns of Escherichia coli. Escherichia coli was isolated from 40 frozen shrimp samples; a total of 25 and 15 shrimp samples were imported from China and Vietnam, respectively. Of the 40 examined fr

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Adeyemi, F. M., та S. B. Akinde. "ESβL, AmpC and carbapenemase co-production in multi-drug resistant Gram-negative bacteria from HIV-infected patients in southwestern Nigeria". African Journal of Clinical and Experimental Microbiology 22, № 1 (2021): 38–51. http://dx.doi.org/10.4314/ajcem.v22i1.6.

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Background: The rising global emergence of Gram-negative bacteria (GNB) producing β-lactam hydrolysing enzymes in clinical infections constitutes a growing public health threat. This study investigated the occurrence of co-production of extended spectrum β-lactamase (ESβL), AmpC β-lactamases, and carbapenemases among GNB isolated from HIVinfected patients in two tertiary healthcare facilities in southwest Nigeria.Methodology: A total of 115 GNB isolates previously recovered from HIV-infected patients at the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, and the State Specialis

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Karim, Md Rezaul, Zunita Zakaria, Latiffah Hassan, Nik Mohd Faiz, and Nur Indah Ahmad. "Antimicrobial Resistance Profiles and Co-Existence of Multiple Antimicrobial Resistance Genes in mcr-Harbouring Colistin-Resistant Enterobacteriaceae Isolates Recovered from Poultry and Poultry Meats in Malaysia." Antibiotics 12, no. 6 (2023): 1060. http://dx.doi.org/10.3390/antibiotics12061060.

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The co-existence of the colistin resistance (mcr) gene with multiple drug-resistance genes has raised concerns about the possibility of the development of pan-drug-resistant bacteria that will complicate treatment. This study aimed to investigate the antibiotic resistance profiles and co-existence of antibiotic resistance genes among the colistin-resistant Enterobacteriaceae isolates recovered from poultry and poultry meats. The antibiotic susceptibility to various classes of antibiotics was performed using the Kirby-Bauer disk diffusion method and selected antimicrobial resistance genes were

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Taii, Noor, Nagham Gburi, and Nuha Khalil. "Detection of biofilm formation and antibiotics resistance of Staphylococcus spp. isolated from humans’ and birds’ oral cavities." Open Veterinary Journal 14, no. 9 (2024): 2215. http://dx.doi.org/10.5455/ovj.2024.v14.i9.9.

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Background: Staphylococcus spp. are widely distributed in nature and can cause nosocomial, skin infections, and foodborne illness, and it may lead to severe financial losses in birds by causing systemic infection in numerous organs. Aim: This study was conducted to determine the prevalence of Staphylococcus spp. in humans and birds in Baghdad city. Methods: Seventy-six oral cavity swabs were collected, including 41 from birds and 35 from breeders. All samples were examined by bacteriological methods and identified by using the VITEK technique, the samples were then further studied to test the

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Mirzaei, Arezoo, Bahram Nasr Esfahani, Abbasali Raz, Mustafa Ghanadian та Sharareh Moghim. "From the Urinary Catheter to the Prevalence of Three Classes of Integrons, β-Lactamase Genes, and Differences in Antimicrobial Susceptibility of Proteus mirabilis and Clonal Relatedness with Rep-PCR". BioMed Research International 2021 (10 червня 2021): 1–10. http://dx.doi.org/10.1155/2021/9952769.

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Introduction. Proteus mirabilis is a biofilm-forming agent that quickly settles on the urinary catheters and causing catheter-associated urinary tract infections. Thus, the spread of multidrug-resistant P. mirabilis isolates, with the ability to form a biofilm that carries integron, extended-spectrum β-lactamases (ESBLs), and plasmid-mediated colistin resistance genes (mcr), represents a severe threat to managing nosocomial infectious diseases. This study is aimed at surveying the prevalence of ESBL, integrase, and mcr genes of P. mirabilis, isolated from the catheter, to assess the difference

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Mirza, S., S. Kariuki, K. Z. Mamun, N. J. Beeching, and C. A. Hart. "Analysis of Plasmid and Chromosomal DNA of Multidrug-Resistant Salmonella enterica Serovar Typhi from Asia." Journal of Clinical Microbiology 38, no. 4 (2000): 1449–52. http://dx.doi.org/10.1128/jcm.38.4.1449-1452.2000.

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Molecular analysis of chromosomal DNA from 193 multidrug-resistant (MDR) Salmonella enterica serovar Typhi isolates from 1990 to 1995 from Pakistan, Kuwait, Malaysia, Bangladesh, and India produced a total of five major different pulsed-field gel electrophoresis (PFGE) patterns. Even within a particular country MDR S. entericaserovar Typhi DNA was found to be in different PFGE groups. Similar self-transferable 98-MDa plasmids belonging to either incompatibility group incHI1 or incHI1/FIIA were implicated in the MDR phenotype inS. enterica serovar Typhi isolates from all the locations except Qu

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AL-Ezzy, Ali Ibrahim Ali, Sarah Amer Al-Azawi, and Ammar Riad Algburi. "Multidrug Resistant Behavior Of P Mirabilis Isolated From patients Urinary Tract Infections." Diyala Journal for Veterinary Sciences 1, no. 1 (2023): 1–15. https://doi.org/10.71375/djvs.2023.01101.

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The aim of this study was to isolate and identify of Proteus mirabilis from patients with UTI and eval-uate its sensitivity to commonly used antibiotics . Proteus mirabilis was isolated from 60 of 250 samples , (24%). Proteus mirabilis was absolute resistant to ampicillin, amoxicillin-clavulanic acid and trimethoprim -sulfamethoxazole. A total of 90% of Proteus mirabilis isolates were resistant to ceftriaxone, cefotaxime and cefixime; 80% were resistant to nitofurantoin and 70% were resistant to nalidixic acid. However, 90% of Proteus mirabilis showed a sensitivity to amikacin, 70 % to cefoxit

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Alghamdi, Molook, Effat Al-Judaibi, Mohammed Al-Rashede, and Awatif Al-Judaibi. "Comparative De Novo and Pan-Genome Analysis of MDR Nosocomial Bacteria Isolated from Hospitals in Jeddah, Saudi Arabia." Microorganisms 11, no. 10 (2023): 2432. http://dx.doi.org/10.3390/microorganisms11102432.

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Multidrug-resistant (MDR) bacteria are one of the most serious threats to public health, and one of the most important types of MDR bacteria are those that are acquired in a hospital, known as nosocomial. This study aimed to isolate and identify MDR bacteria from selected hospitals in Jeddah and analyze their antibiotic-resistant genes. Bacteria were collected from different sources and wards of hospitals in Jeddah City. Phoenix BD was used to identify the strains and perform susceptibility testing. Identification of selected isolates showing MDR to more than three classes on antibiotics was b

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Pringgenies, Delianis, Wilis Ari Setyati, Ali Djunaedi, Rini Pramesti, Siti Rudiyanti, and Dafit Ariyanto. "Exploration of Antimicrobial Potency of Mangrove Symbiont Against Multi-Drug Resistant Bacteria." Jurnal Ilmiah Perikanan dan Kelautan 13, no. 2 (2021): 222–32. http://dx.doi.org/10.20473/jipk.v13i2.26199.

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Highlight ResearchAntimicrobial potential against the test microbesRhizhopora mucronata isolate showed 95% homology with Bacillus subtilis, and 97% homology with Bacillus oceanisediminis,Acanthus ilicifolius isolate showed 96% homology with Paracoccus caeni, and 89% homology with Bacillus circulans. The study found 4 isolates with antimicrobial potency against MDR pathogenic microbes.The symbiont microbes taken from Rhizophora mucronata and Acanthus ilicifolius were determined to be of the genus Bacillus and Paracoccus AbstractAntimicrobial property of mangrove symbiont have the ability to fig

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Mukherjee, Maitreyee, Terry Gentry, Heidi Mjelde, et al. "Escherichia coli Antimicrobial Resistance Variability in Water Runoff and Soil from a Remnant Native Prairie, an Improved Pasture, and a Cultivated Agricultural Watershed." Water 12, no. 5 (2020): 1251. http://dx.doi.org/10.3390/w12051251.

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Although many previous studies have examined patterns of antimicrobial resistance (AMR) and multidrug resistance (MDR) from domestic animals and farm environments, comparatively little is known about the environmental sources and natural reservoirs of AMR and MDR. In this study, we collected stormwater runoff and soil samples from three watersheds in Texas. Escherichia coli (E. coli) were enumerated, isolated, and analyzed for resistance patterns. E. coli from all sites, irrespective of land use, displayed the presence of AMR/MDR. Higher levels of AMR/MDR were observed in water compared to soi

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Kiley, John, Katrin Mende, Susan J. Kaiser, et al. "1184. Resistance Patterns and Susceptibility Analysis of Klebsiella pneumoniae Infections in Service Members Who Sustained Trauma in Iraq and Afghanistan." Open Forum Infectious Diseases 5, suppl_1 (2018): S357—S358. http://dx.doi.org/10.1093/ofid/ofy210.1017.

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Abstract Background Klebsiella pneumoniae was the third most common species of multidrug-resistant (MDR) Gram-negative organism in military trauma patients injured in Iraq and Afghanistan (2009–2014). This study aims to characterize the antimicrobial susceptibility and resistance patterns of K. pneumoniae isolates in these patients. Methods All infecting K. pneumoniae isolates (IKpI) archived by the Trauma Infectious Disease Outcomes Study (TIDOS) and 96 colonizing isolates (CKpI) from groin swabs were included (6/09-12/14). All CKpI linked with IKpI were included; the remainder to total 50 MD

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Al Momani, Waleed M., Nour Ata, and Ahmed O. Maslat. "Colistin-resistance genes in Escherichia coli isolated from patients with urinary tract infections." PLOS ONE 19, no. 6 (2024): e0305431. http://dx.doi.org/10.1371/journal.pone.0305431.

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Background The incidence of antimicrobial resistance is alarmingly high because it occurs in humans, environment, and animal sectors from a “One Health” viewpoint. The emergence of plasmid-carried mobile colistin-resistance (MCR) genes limits the efficacy of colistin, which is the last-line treatment for multidrug resistance (MDR) against gram-negative infections. Objectives The current study aimed to investigate emergence of colistin-resistance (MCR 1–5) genes in E. coli isolated from patients with urinary tract infections (UTIs) in Jordan. Methods E. coli (n = 132) were collected from urine

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Falodun, Olutayo Israel, and Adams Agbo Ameh. "Multidrug resistance and virulence genes in Campylobacter isolates from poultry waste in Ibadan, Nigeria." One Health Bulletin 4, no. 1 (2024): 39–46. http://dx.doi.org/10.4103/ohbl.ohbl_36_23.

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Objective: This study aims to determine antibiotic susceptibility profile and detect virulence genes in Campylobacter spp. isolated from poultry waste in Ibadan, Nigeria. Methods: Poultry droppings were collected from ten poultry farms, and Total Bacteria Count (TBC) and Total Anaerobic Count (TAC) of the samples were determined. Campylobacter species were isolated using modified Charcoal Cefoperazone Deoxycholate Agar (mCCDA). The isolates were identified using conventional biochemical techniques, and antibiotics susceptibility testing was performed using Kirby Bauer disk diffusion assay on M

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Weill, François-Xavier, Laëtitia Fabre, Bernadette Grandry, Patrick A. D. Grimont, and Isabelle Casin. "Multiple-Antibiotic Resistance in Salmonella enterica Serotype Paratyphi B Isolates Collected in France between 2000 and 2003 Is Due Mainly to Strains Harboring Salmonella Genomic Islands 1, 1-B, and 1-C." Antimicrobial Agents and Chemotherapy 49, no. 7 (2005): 2793–801. http://dx.doi.org/10.1128/aac.49.7.2793-2801.2005.

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ABSTRACT This study was conducted to investigate the occurrence of multiple-antibiotic resistance among 261 clinical isolates of Salmonella enterica serotype Paratyphi B strains collected between 2000 and 2003 through the network of the French National Reference Center for Salmonella. The 47 multidrug-resistant (MDR) isolates identified (18%), were characterized on the basis of the presence of several resistance genes (bla TEM, bla PSE-1, bla CTX-M, floR, aadA2, qacEΔ1, and sul1), the presence of Salmonella genomic island 1 (SGI1) by PCR mapping and hybridization, and the clonality of these is

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Lubna, Abdulazeem, Adnan Hasan ALAWADI Suhad, Ali Khait Maysaa, Adnan Ali Hiyam, ali sayb Shahad, and Abd Al-Hadi Abd Al-Karim Kwthar. "Extracted of Pyocyanin from Pseudomonas Aeruginosa and Determination Their Activity as Anti MDR Bacteria." INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH 04, no. 05 (2025): 276–80. https://doi.org/10.5281/zenodo.15448567.

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Objective: Using the Vitek-2 technology, bacteria were identified and pyocyanin was recovered from environmental Pseudomonas aeruginosa that was isolated from different soil in Hilla City. Various pigment concentrations were tested for their antibacterial properties against pathogenic bacteria that cause burns and wound infections. The findings demonstrated that pigment had a positive impact on all bacteria.Methods: After Pseudomonas aeruginosa from burns and wounds was isolated and identified, isolates that could generate pyocyanin to inhibit the development of certain pathogenic isolated bac

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Alvarez, Luis, Dennis Carhuaricra, Joel Palomino-Farfan, Sonia Calle, Lenin Maturrano, and Juan Siuce. "Genomic Profiling of Multidrug-Resistant Swine Escherichia coli and Clonal Relationship to Human Isolates in Peru." Antibiotics 12, no. 12 (2023): 1748. http://dx.doi.org/10.3390/antibiotics12121748.

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The misuse of antibiotics is accelerating antimicrobial resistance (AMR) in Escherichia coli isolated from farm animals. The genomes of ten multidrug-resistant (MDR) E. coli isolates from pigs were analyzed to determine their sequence types, serotypes, virulence, and AMR genes (ARGs). Additionally, the relationship was evaluated adding all the available genomes of Peruvian E. coli from humans using the cgMLST + HierCC scheme. Two aEPEC O186:H11-ST29 were identified, of which H11 and ST29 are reported in aEPEC isolates from different sources. An isolate ETEC-O149:H10-ST100 was identified, consi

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Rahman, Md Tarekur, Muhammad Asaduzzaman, Sreedam Chandra Das, Md Saiful Islam, Sarder Arifuzzaman, and Zubair Khalid Labu. "Biochemical Characterization and Antibiotic Susceptibility Analysis of Escherichia coli and Salmonella typhi Isolated from Clinical Sample." Bangladesh Pharmaceutical Journal 28, no. 1 (2025): 94–104. https://doi.org/10.3329/bpj.v28i1.79469.

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Poor sensitivity of pathogenic bacteria to bacteria is a serious health issue worldwide specially in the developing and underdeveloped countries making greater concern to the scientists. This study followed the CLSI (Clinical and Laboratory Standards Institute) guidelines 30, Kirby-Bauer disc diffusion method to test sensitivity. We analyzed the antibiotic sensitivity pattern of Escherichia coli and Salmonella typhi isolated from clinical samples, collected from two hospitals of Dhaka, Bangladesh. The sensitivity of twelve different single antibiotics (cefepime, cefotaxime, chloramphenicol, ci

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Suárez-Pérez, Alejandro, Juan Alberto Corbera, Margarita González-Martín, and María Teresa Tejedor-Junco. "Multidrug-Resistant Phenotypes of Escherichia coli Isolates in Wild Canarian Egyptian Vultures (Neophron percnopterus majorensis)." Animals 11, no. 6 (2021): 1692. http://dx.doi.org/10.3390/ani11061692.

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The presence of multidrug-resistant (MDR) Escherichia coli in cloacal samples from Canarian Egyptian vultures was investigated. Samples were obtained from chicks (n = 65) and from adults and immature birds (n = 38). Antimicrobial susceptibility to 16 antibiotics included in 12 different categories was determined for 103 E. coli isolates. MDR was defined as acquired non-susceptibility to at least one agent in three or more antimicrobial categories. Forty-seven different resistance phenotypes were detected: 31 MDR (41 isolates) and 16 non-MDR (62 isolates). One isolate was resistant to all 12 an

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LAZAR, Cristina Ioana, Gheorghita DUCA, Carmen Dana SANDRU, et al. "ANTIBIOTIC PROFILE OF BACTERIA ISOLATED FROM THE SKIN SURFACE FROM EXTENSIVELY RAISED SWINE." AgroLife Scientific Journal 11, no. 2 (2022): 80–84. http://dx.doi.org/10.17930/agl2022210.

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Antibiotic resistance of Staphylococcus is increasing worldwide and is becoming a global concern. The present report exposes the study of the antibiotic susceptibility in isolates of Staphylococcus spp obtained from farm pigs. The samples were collected from healthy pigs, from different farms, in the period between 2019-2020. Forty strains of Staphylococcus were isolated from the anterior nares of individual pigs, and from the skin behind the ears of the animals. These isolates were tested against 12 different antimicrobial agents using the Kirby-Bauer disk-diffusion method. The antibiotic sus

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