Academic literature on the topic 'Méthode des Interaction sol-structure'
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Journal articles on the topic "Méthode des Interaction sol-structure"
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Iwasaki, Fujiko, Joseph H. Yoshikawa, Hajime Yamamoto, Kiwamu Takada, Eiji Kan-nari, Masanori Yasui, Takayuki Ishida, and Takashi Nogami. "TEMPO radicals showing magnetic interactions. II. 4-(Benzylideneamino)-TEMPO and related compounds." Acta Crystallographica Section B Structural Science 55, no. 6 (December 1, 1999): 1057–67. http://dx.doi.org/10.1107/s0108768199007326.
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X-ray crystal structure analyses were performed on 4-(Ar-methyleneamino)-TEMPO radicals at room temperature (TEMPO = 2,2,6,6-tetramethylpiperidyl-1-oxyl): Ar = Ph [4-(benzylideneamino)-2,2,6,6-tetramethylpiperidyl-1-oxyl], 4-MeS-Ph [2,2,6,6-tetramethyl-4-(4-methylthiobenzylideneamino)piperidyl-1-oxyl], 4-Me-Ph [4-(4-methylbenzylideneamino)-2,2,6,6-tetramethylpiperidyl-1-oxyl], 4-PhO-Ph [2,2,6,6-tetramethyl-4-(4-phenoxybenzylideneamino)piperidyl-1-oxyl], 4-MeSO_{2}-Ph [2,2,6,6-tetramethyl-4-(4-methylsulfonylbenzylideneamino)piperidyl-1-oxyl], 3-Py [2,2,6,6-tetramethyl-4-(3-pyridylmethylideneamino)piperidyl-1-oxyl] and 2-Naph [2,2,6,6-tetramethyl-4-(2-naphthylideneamino)piperidyl-1-oxyl]. Structures of Ph and 4-Me-Ph derivatives were also determined at 100 K. Some of these crystals have been revealed to show intermolecular ferromagnetic interactions at an extremely low temperature. Structural features of crystals of Ph, 4-MeS-Ph and 3-Py derivatives, which show ferromagnetic interactions, are very similar to each other. In these crystals, O atoms are arranged to form a sheet. The ferromagnetic interactions are considered to be transferred through O...H van der Waals' interactions of the \beta-H atoms of the neighboring TEMPO rings within the sheet. Between O...O sheets, the aryl groups are arranged in a herringbone manner. The crystal structure of the 4-Me-Ph derivative, which shows an antiferromagnetic interaction, is also pseudo-isostructural with those of Ph, 4-MeS-Ph and 3-Py derivatives, while the arrangement of the aryl groups is different. The packing mode of the crystals of the 4-MeSO_{2}-Ph derivative, of which the Weiss constant \theta is nearly zero, is very different from those of the other derivatives showing magnetic interactions. The fact that the crystal structure of the paramagnetic 4-MeSO_{2}-Ph derivative does not show the O...O sheet structure accompanying the O...\beta-H interactions indicates that the intermolecular ferromagnetic interactions through \beta-H atoms within the O...O sheet are important for these TEMPO radical crystals.
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Varga, Vojtech, Jiří Pinkas, Ivana Císařová, Róbert Gyepes, Karel Mach, Jiří Kubišta, and Michal Horáček. "Synthesis and Structure of Permethylcyclopentadienyltitanium Diisopropoxide Zwitterionic Complex." Collection of Czechoslovak Chemical Communications 73, no. 8-9 (2008): 1161–76. http://dx.doi.org/10.1135/cccc20081161.
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Half-sandwich pentamethylcyclopentadienyltitanium chloroisopropoxides [Ti(η5-C5Me5)-Ti(Oi-Pr)nCl3-n] (n = 1 (1) or 2 (2)) and methylisopropoxides [Ti(η5-C5Me5)Ti(Oi-Pr)nMe3-n] (n = 1 (3) or 2 (4)) were prepared and characterized by spectroscopic methods, and compound 1 by single crystal X-ray diffraction analysis. Compounds 3 and 4 were reacted with an equimolar quantity of B(C6F5)3, however, only compound 4 afforded a crystalline product of limited stability at ambient temperature. Its single crystal X-ray diffraction analysis revealed that it is the zwitterionic complex [(η5-C5Me5)Ti(Oi-Pr)2]+[(μ-Me)B(C6F5)3]- (5) and its crystal structure is very similar to the recently reported tert-butoxy complex [(η5-C5Me5)-Ti(Ot-Bu)2]+[(μ-Me)B(C6F5)3]- (6). The 1H, 13C, and 19F NMR spectra in C6D6 solution also showed the features analogous to those of 6. 1D NOESY experiments proved a close through space interaction of irradiated C5Me5 or OCHMe2 protons with the bridging Ti···Me-B group. The NMR data indicate the inner sphere ion pair structure of 5 in C6D6, like for 6. The crystal structure geometry of the C-H bonds of the Ti···Me-B group fulfils conditions for their agostic interaction with the titanium centre. Although structurally similar to 6, compound 5 is less thermally stable apparently due to a lower bulkiness of Oi-Pr group compared to that of Ot-Bu group.
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Akune, Yoko, Risa Hirosawa, Atsushi Koseki, and Shinya Matsumoto. "Role of halogen substituents in a series of polymorphic 2,5-diamino-3,6-dicyanopyrazine derivatives with highly flexible groups." Zeitschrift für Kristallographie - Crystalline Materials 232, no. 5 (May 1, 2017): 395–405. http://dx.doi.org/10.1515/zkri-2016-2007.
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AbstractThe crystal structures of the ortho-X-benzyl derivatives, where X=F, Cl, Br, I, and Me, of 2,5-bis(N,N-dibenzylamino)-3,6-dicyanopyrazine dyes (C34H24N6X4) were analysed to evaluate the effect of a systematic series of structures on the occurrence of polymorphism. Detailed crystal structure analysis indicated that the thermally stable forms of the polymorphic derivatives (Cl and Br derivatives) were close-packed, whereas those of the non-polymorphic derivatives (F and I derivatives) were stabilised by an intermolecular interaction involving the ortho-substituents. In the thermally metastable forms of the polymorphic derivative, halogen-halogen and halogen-nitrogen interactions contributed to the stabilisation of these crystals in the same way as the thermally stable form of the non-polymorphic derivatives. This indicated that the ease of polymorph occurrence would require an appropriate balance between the crystal energy of the close-packed structure and that of the crystal structure generated mainly by the electrostatic interactions involving the halogens in these halogenated pyrazine derivatives. In addition, the similar tendency of the occurrence of polymorphs in these halogenated pyrazine derivatives was found in 19 sets of halogenated compounds having known crystal structures of F, Cl, Br and I derivatives including at least one polymorphic derivative in the crystal structure database.
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Yamaguchi, Torahiko, and Yohsuke Yamamoto. "Substituent effects on the structure of hexacoordinate carbon bearing two thioxanthene ligands." Pure and Applied Chemistry 85, no. 4 (March 18, 2013): 671–82. http://dx.doi.org/10.1351/pac-con-12-11-05.
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In order to elucidate the electronic nature of our recently reported first hexacoordinated carbon (12-C-6), density functional theory (DFT) calculations of sulfide precursor, sulfone derivative, and S+-F derivative were carried out and compared with those of the reported S+-Me hexacoordinated carbon. Computations on the hexacoordinated carbon, indicating that four attractive C–O interactions with the central hexacoordinate carbon atom exist, also revealed that the interactions consist of two different types of three-center four-electron bonds, which can be regarded as electron donation by the lone pairs of the oxygen atoms to the empty low-lying π*-orbitals of the allene. The optimized structures of the sulfide, sulfone, S+-F, and the original S+-Me suggested that the introduction of electron-withdrawing groups at the sulfur atoms would make the C–O attractive interactions stronger by a larger contribution of the carbon dication resonance structure. Thus, allene compounds (sulfide, sulfone, sulfonium) with two different thioxanthene ligands (one with 1,8-dimethoxy groups as in the S+-Me compound and the other with 1,8-diphenoxy groups) were synthesized to confirm the predicted substituent effects on the C(central)–O interactions. Electron-withdrawing substituents at the sulfur atoms were found to give rise to strong C(central)–O attractive interactions; the average values of the four C–O distances were smaller as the electron-withdrawing ability of the sulfur atoms rose. Additionally, C(central)···OMe distances were shorter than the corresponding C(central)···OPh distances, reflecting the higher electron-donating ability of the oxygen atoms at these 1,8-positions of the thioxanthene skeleton.
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Rando, Gianpaolo, David Horner, Andrea Biserni, Balaji Ramachandran, Donatella Caruso, Paolo Ciana, Barry Komm, and Adriana Maggi. "An Innovative Method to Classify SERMs Based on the Dynamics of Estrogen Receptor Transcriptional Activity in Living Animals." Molecular Endocrinology 24, no. 4 (April 1, 2010): 735–44. http://dx.doi.org/10.1210/me.2009-0514.
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Abstract Using a mouse model engineered to measure estrogen receptor (ER) transcriptional activity in living organisms, we investigated the effect of long-term (21 d) hormone replacement on ER signaling by whole-body in vivo imaging. Estrogens and selective ER modulators were administered daily at doses equivalent to those used in humans as calculated by the allometric approach. As controls, ER activity was measured also in cycling and ovariectomized mice. The study demonstrated that ER-dependent transcriptional activity oscillated in time, and the frequency and amplitude of the transcription pulses was strictly associated with the target tissue and the estrogenic compound administered. Our results indicate that the spatiotemporal activity of selective ER modulators is predictive of their structure, demonstrating that the analysis of the effect of estrogenic compounds on a single surrogate marker of ER transcriptional activity is sufficient to classify families of compounds structurally and functionally related. For more than one century, the measure of drug structure-activity relationships has been based on mathematical equations describing the interaction of the drug with its biological receptor. The understanding of the multiplicity of biological responses induced by the drug-receptor interaction demonstrated the limits of current approach and the necessity to develop novel concepts for the quantitative analysis of drug action. Here, a systematic study of spatiotemporal effects is proposed as a measure of drug efficacy for the classification of pharmacologically active compounds. The application of this methodology is expected to simplify the identification of families of molecules functionally correlated and to speed up the process of drug discovery.
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Malinska, Maura, Aleksandra Kieliszek, Anna E. Kozioł, Barbara Mirosław, and Krzysztof Woźniak. "Interplay between packing, dimer interaction energy and morphology in a series of tricyclic imide crystals." Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials 76, no. 2 (March 6, 2020): 157–65. http://dx.doi.org/10.1107/s2052520620001304.
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Crystal morphology is a very important feature in many industrial applications. Tricyclic imides, derivatives of 10-oxa-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione with differing small hydrophobic groups (Me, Et), were studied and grouped based on Etter's rule. Using experimental X-ray studies, dimer energy calculations, framework analysis and periodic DFT-D calculations, it is shown that knowledge of the hydrogen-bond pattern can be used to determine the final crystal shape. Molecules forming a ring hydrogen-bond motif crystallize as plate crystals with the {100} facet as the slowest growing, whereas those molecules forming an infinite hydrogen-bond motif in the crystal structure crystallize as needles with the {101} facet having the largest surface area.
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Handa, Makoto, Satoshi Nishiura, Makoto Kano, Natsumi Yano, Haruo Akashi, Masahiro Mikuriya, Hidekazu Tanaka, Tatsuya Kawamoto, and Yusuke Kataoka. "Structures and Properties of 4-phpy, pyz, and 4,4′-bpy Adducts of Lantern-Type Dirhodium Complexes with µ-Formamidinato and µ-Carboxylato Bridges." Magnetochemistry 7, no. 3 (March 15, 2021): 39. http://dx.doi.org/10.3390/magnetochemistry7030039.
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Dinuclear and polymer complexes of 4-phenylpyridine (4-phpy), pyazine (pyz), and 4,4′-bipyridine (4,4′-bpy) were prepared by using cis-[Rh2(4-Me-pf)2(O2CR)2] (4-Me-pf- =N,N’-bis(4-methylphenyl)formamidinate anion; R = CF3 and CMe3) as precursor dinuclear units. The dinuclear structures of cis-[Rh2II,II(4-Me-pf)2(O2CR)2(4-phpy)2] and cis-[Rh2II,III(4-Me-pf)2(O2CCMe3)2(4-phpy)2]BF4 and polymer structures of [Rh2II,II(4-Me-pf)2(O2CR)2(L)]n (L = pyz and 4,4′-bpy) were confirmed by X-ray crystal structure analyses. In these complexes, the lantern-type dinuclear core structures with cis-(2:2) arrangement of formamidinato (4-Me-pf-) and carboxylato ligands are preserved with Rh–Rh distances of 2.44–2.47 Å, regardless of the difference in the axial ligand and oxidation state Rh2II,II or Rh2II,III. In the cyclic voltammograms (CVs) in CH2Cl2, the redox potentials for Rh2II,III/Rh2II,II were estimated as E1/2 = 0.07 V and −0.28 V (vs. Fc+/Fc) for cis-[Rh2(4-Me-pf)2(O2CCF3)2(4-phpy)2] and cis-[Rh2(4-Me-pf)2(O2CCMe3)2(4-phpy)2], respectively, negatively shifted by 0.16 and 0.12 V compared with those of corresponding parent dinuclear complexes. The results were interpreted that the axial interaction with 4-phpy ligands makes the Rh2II,II core oxidized easily. The oxidized complex cis-[Rh2(4-Me-pf)2(O2CCMe3)2(4-phpy)2]BF4 is paramagnetic, which was confirmed by effective magnetic moment value μeff = 1.90 μB at 300 K per Rh2II,III unit (S = 1/2). The polymer complexes [Rh2(4-Me-pf)2(O2CR)2(L)]n (L = pyz and 4,4′-bpy) showed Type II gas-adsorption properties for N2.
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Ferrer-Ugalde, Albert, Arántzazu González-Campo, José Giner Planas, Clara Viñas, Francesc Teixidor, Isabel M. Sáez, and Rosario Núñez. "Tuning the Liquid Crystallinity of Cholesteryl-o-Carborane Dyads: Synthesis, Structure, Photoluminescence, and Mesomorphic Properties." Crystals 11, no. 2 (January 28, 2021): 133. http://dx.doi.org/10.3390/cryst11020133.
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A set of mesomorphic materials in which the o-carborane cluster is covalently bonded to a cholesteryl benzoate moiety (mesogen group) through a suitably designed linker is described. The olefin cross-metathesis between appropriately functionalized styrenyl-o-carborane derivatives and a terminal alkenyl cholesteryl benzoate mesogen (all type I terminal olefins) leads to the desired trans-regioisomer, which is the best-suited configuration to obtain mesomorphic properties in the final materials. The introduction of different substituents (R = H (M2), Me (M3), or Ph (M4)) to one of the carbon atoms of the o-carborane cluster (Ccluster) enables the tailoring of liquid crystalline properties. Compounds M2 and M3 show the chiral nematic (N*) phase, whereas M4 do not show liquid crystal behavior. Weaker intermolecular interactions in the solid M3 with respect to those in M2 may allow the liquid crystallinity in M3 to be expressed as enantiotropic behavior, whereas breaking the stronger intermolecular interaction in the solid state of M2 leads directly to the isotropic state, resulting in monotropic behavior. Remarkably, M3 also displays the blue phase, which was observed neither in the chiral nematic precursor nor in the styrenyl-cholesterol model (M5) without an o-carborane cluster, which suggests that the presence of the cluster plays a role in stabilizing this highly twisted chiral phase. In the carborane-containing mesogens (M2 and M3), the o-carborane cluster can be incorporated without destroying the helical organization of the mesophase.
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Castro, Daniel, Filipa Ferreira, Ana Sofia Mendes, and Tiago Bento Ferreira. "Bridges Between Bipolar and Borderline Personality Disorders: Clarifying Comorbidity Through the Analysis of the Complex Network of Connections Between Symptoms." Psychologist: Practice & Research Journal 1, no. 1 (July 23, 2018): 45. http://dx.doi.org/10.33525/pprj.v1i1.45.
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Background: The reasons for the high rates of comorbidity between Bipolar (BD) and Borderline Personality (BPD) disorders remain elusive, due to the vast array of shared clinical features, which makes the differential diagnosis difficult. This constitutes an obstacle to provide quality of care services, which results in detrimental effects on individual’s mental health. The analysis of the complex network of connections between symptoms of both disorders is a promising pathway to uncover the mechanisms underlying the comorbidity structure of both disorders. Goals: In this study, we explored the comorbidity network that represents the connections between 32 DSM-5 symptoms of BD and BPD in order to (1) compare its modular structure (i.e., the constitution of cohesive subgroups of symptoms within the comorbidity network) with the nosographic proposal of the DSM-5; (2) distinguish between the different roles those symptoms have in the comorbidity network and identify the symptoms that overlap and bridge both disorders, as well as the distinctive symptoms that better discriminate them; (3) identify the most central symptoms and those with the highest impact on the strength or on the structure of the connections on the comorbidity network; and (4) analyze the association between symptoms roles and their centrality and impact.Methods: An epidemiological sample from the National Comorbidity Survey: Baseline (NCS) was analyzed. Data regarding bipolar and borderline personality symptoms were collected through the Composite Network International Diagnostic Interview (CIDI). The network of complex interactions between symptoms was estimated using the Ising model with the L1-regularization penalty (EBIC) and the nosographic structure was detailed with Moduland algorithms. Results: Data regarding an overall sample of 7556 individuals was analyzed (48.6% male, Mage = 33.400 years, SDage = 10.447). Results revealed differences between the modular structure of the comorbidity network and the DSM-5 nosographic proposal, namely about unstable relationships and substance abuse, that were assigned to the module constituted by symptoms of manic episode (ME). Symptoms such as money spending and sexual indiscretions, that overlap ME and BPD in the DSM-5, were assigned to the ME module. Psychomotor agitation, which overlaps depressive episode (DE) and ME in the DSM-5, was assigned to the DE module. Additionally, emptiness and worthlessness were identified as bridge symptoms between DE and BPD; anger and substance abuse between ME and BPD; and unstable relationships and psychomotor agitation between DE and ME. Fatigue was the most distinctive symptom of the DE module, unstable relationships of the ME module, and anger of the BPD module. Strength centrality (r = .61, 95%CI [.33, .79], p < .001) and modular bridgeness (r = .64, 95%CI [.38, .81], p < .001) were positively correlated with the impact on the structure of the comorbidity network; and modular overlap was negatively correlated with the impact on the strength (r = -.43, 95%CI [-.10, -.68], p = .01) of its connections. Discussion: Results suggest a similar structure of the comorbidity network to the nosographic proposal of DSM-5. Distinctive and bridge symptoms were identified for each disorder which might help with the differential diagnosis. It can also help us to unveil possible development pathways of comorbidity that might promote an improvement in psychological treatments. Keywords: Bipolar disorder, Borderline personality disorder, Network analysis, Comorbidity.
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Bojarska, Joanna, Milan Remko, Izabela D. Madura, Krzysztof Kaczmarek, Janusz Zabrocki, and Wojciech M. Wolf. "Synthesis, experimental and in silico studies of N-fluorenylmethoxycarbonyl-O-tert-butyl-N-methyltyrosine, coupled with CSD data: a survey of interactions in the crystal structures of Fmoc–amino acids." Acta Crystallographica Section C Structural Chemistry 76, no. 4 (March 10, 2020): 328–45. http://dx.doi.org/10.1107/s2053229620003009.
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Recently, fluorenylmethoxycarbonyl (Fmoc) amino acids (e.g. Fmoc–tyrosine or Fmoc–phenylalanine) have attracted growing interest in biomedical research and industry, with special emphasis directed towards the design and development of novel effective hydrogelators, biomaterials or therapeutics. With this in mind, a systematic knowledge of the structural and supramolecular features in recognition of those properties is essential. This work is the first comprehensive summary of noncovalent interactions combined with a library of supramolecular synthon patterns in all crystal structures of amino acids with the Fmoc moiety reported so far. Moreover, a new Fmoc-protected amino acid, namely, 2-{[(9H-fluoren-9-ylmethoxy)carbonyl](methyl)amino}-3-{4-[(2-hydroxypropan-2-yl)oxy]phenyl}propanoic acid or N-fluorenylmethoxycarbonyl-O-tert-butyl-N-methyltyrosine, Fmoc-N-Me-Tyr(t-Bu)-OH, C29H31NO5, was successfully synthesized and the structure of its unsolvated form was determined by single-crystal X-ray diffraction. The structural, conformational and energy landscape was investigated in detail by combined experimental and in silico approaches, and further compared to N-Fmoc-phenylalanine [Draper et al. (2015). CrystEngComm, 42, 8047–8057]. Geometries were optimized by the density functional theory (DFT) method either in vacuo or in solutio. The polarizable conductor calculation model was exploited for the evaluation of the hydration effect. Hirshfeld surface analysis revealed that H...H, C...H/H...C and O...H/H...O interactions constitute the major contributions to the total Hirshfeld surface area in all the investigated systems. The molecular electrostatic potentials mapped over the surfaces identified the electrostatic complementarities in the crystal packing. The prediction of weak hydrogen-bonded patterns via Full Interaction Maps was computed. Supramolecular motifs formed via C—H...O, C—H...π, (fluorenyl)C—H...Cl(I), C—Br...π(fluorenyl) and C—I...π(fluorenyl) interactions are observed. Basic synthons, in combination with the Long-Range Synthon Aufbau Modules, further supported by energy-framework calculations, are discussed. Furthermore, the relevance of Fmoc-based supramolecular hydrogen-bonding patterns in biocomplexes are emphasized, for the first time.
Book chapters on the topic "Méthode des Interaction sol-structure"
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Orr, David W. "Education, Careers, and Callings." In The Nature of Design. Oxford University Press, 2002. http://dx.doi.org/10.1093/oso/9780195148558.003.0024.
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In the past decade I have received several hundred letters of inquiry from students asking for advice about education and careers. Most want to know how to combine their passion for the natural world with formal education in order to craft a useful life. The letters and e-mails are often written in a tone of frustration. An undergraduate biology major, for example, writes: “I have been researching my options, and I have come to the conclusions [sic] that there are quite a number of programs labeled ‘conservation biology’ or ‘environmental studies’ around the country. It is fairly easy to become lost in a sea of them. I attended the Society for Conservation Biology meeting in Maryland, but failed to find any prospective advisors. Would you have any advice to offer on this topic?” Similarly, a recent Ph.D. in wildlife biology writes: “I am struggling to translate my professional training into a life well lived that in some way might contribute to preserving the natural world and not just documenting its decline. . . . My professional training did not prepare me well for these tasks.” Dozens of other letters have the same plaintive themes. The problem is not simply that there are many more students who want practical careers in environmental work than those who find them. The deeper problem has to do with the experience of students as they pass through the system of higher education. Whatever they once may have been, institutions of higher education have become vast and expensively operated machines much like any for-profit corporation. Students are fed through a conveyor belt of requirements, large classes, deadlines, and general busy-ness. What they learn seldom adds up to anything like a coherent, ecologically solvent worldview. The scale of most institutions is not conducive to humane interaction. Seldom encouraged to discern an inner calling, students are more often counseled to find secure careers that pay well. Nonetheless, many students still feel a calling toward service that runs counter to the incentives, values, and structure of their formal education.
Conference papers on the topic "Méthode des Interaction sol-structure"
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Sheer, Francis J., and Samir N. Ghadiali. "Parametric Analysis of Eustachian Tube Function Using Fully Coupled Fluid-Structure Interaction Models." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19425.
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Otitis Media (OM) is the most commonly diagnosed childhood illness and has health care related cost of four billion dollars annually. [1] The onset of OM has been directly related to Eustachian Tube (ET) dysfunction. The ET has three main physiological functions, and when these functions are compromised, middle ear (ME) disorders arise. It is also known that specific populations of patients, such as those with cranio-facial abnormalities, such as a cleft palate, have a 100% onset rate of OM. Even though ET dysfunction has been related to OM, the underlying reasons for ET dysfunction in certain populations remains unknown. To gain an understanding of this system, we use fully coupled fluid-structure interaction (FSI) models of the ET based on geometries reconstructed from histological images. Using these models in systematic parameter variation studies allows us to identify which parameters of the ET can cause dysfunction. Using healthy adult subjects as a model for a well-functioning ET, we determined ET function to be sensitive to changes in TVP muscle force.
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Kumpaty, Subha, Katie Reichl, and Anand Vyas. "New ABET Student Outcomes Assessment: Developing Performance Indicators and Instruments for Outcome 4." In ASME 2020 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/imece2020-23079.
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Abstract Milwaukee School of Engineering’s Mechanical Engineering Department, having successfully completed the accreditation of the ME program in 2018–19 under the prior a through k student outcomes, dedicated the program meetings during academic year 2019–20 to develop assessment instruments in transitioning to the new ABET Student Outcomes 1–7. By deliberately involving the entire faculty to participate in the development of instruments, a grassroots level discussion and creation ensued for each outcome. The process is showcased in this paper for Student Outcome 4 on ethics as a model to share with our engineering faculty and to highlight salient features in the developed instrument and associated rubrics. The details of performance indicators interwoven across the curriculum and the methods of data collection are provided in a tabular form for ease of expectation and implementation. How the readily available materials from the National Society of Professional Engineers could be incorporated at early years of the baccalaureate program while the outcome’s performance indicators could be assessed at a deeper level during junior and senior years are showcased in this paper. The periodic dialogue among all colleagues who were working on various outcomes ensured proper communication of what one outcome group is prescribing that we do and receive input from those who are involved with the courses in which the data needed to be collected and the performance indicators are to be assessed. The general structure of our standing committees on freshman courses, energy, mechanics, and controls also provided the cushion to review the assessment instruments and provide constructive feedback from the corresponding committee’s perspective. These details of a very interactive Student Outcomes Assessment process will be presented.