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1

Prof., Dr Jalaluddin Akber Dr. Naseeb Ullah Dr. Arshad Hamid Dr. S. Zafar Mehdi Dr. Tahira Saeed Dr. Saleem Ahmed. "MEASLE'S COMPLICATIONS IN ACUTE PHASE IN PCM CHILDREN, PROSPECTIVE STUDY IN A TERTIARY CARE HOSPITAL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 07 (2019): 13561–70. https://doi.org/10.5281/zenodo.3344854.

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<strong><em>Objective:</em></strong> <em>To determine measle&rsquo;s complications in acute phase in PCM children, prospective study in a tertiary care hospital</em> <strong><em>Plae and duration of study: </em></strong><em>Department of Peadiatrics Medicine Baqai Medical Hospital Karachi, from1<sup>st</sup> July 2017 to 30<sup>th</sup> June 2018.</em> <strong><em>Study Design;</em></strong><em> A cross-sectional study</em> <strong><em>Methodology: </em></strong><em>I</em><em>n this study, 100 PCM children between 12 and 60 months of age with PCM classification modified GOMEES clssification gr
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Jain, Reena, and Roosy Aulakh. "Measles-Associated CNS Complications: A Review." Journal of Child Science 12, no. 01 (2022): e172-e181. http://dx.doi.org/10.1055/s-0042-1757914.

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AbstractMeasles virus infection is a common infectious disease of childhood, incidence of which is still high in developing countries. Other than the morbidity associated with the acute systemic infection, the measles virus can cause serious fatal neural complications. It can either enter the brain leading to acute encephalitis like primary measles encephalitis and acute post infectious measles encephalomyelitis or it may persist in brain cells (as mutated virus) leading to long-term neurodegenerative diseases like measles inclusion body encephalitis and subacute sclerosing pan encephalitis. T
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3

Fisher, D. L., S. Defres, and T. Solomon. "Measles-induced encephalitis." QJM 108, no. 3 (2014): 177–82. http://dx.doi.org/10.1093/qjmed/hcu113.

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4

Chen, Robert E., David A. Ramsay, L. L. deVeber, Leo J. Assis, and Simon D. Levin. "Immunosuppressive measles encephalitis." Pediatric Neurology 10, no. 4 (1994): 325–27. http://dx.doi.org/10.1016/0887-8994(94)90131-7.

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5

Huppatz, Clare, Paul M. Kelly, Christopher Levi, Craig Dalton, David Williams, and David N. Durrheim. "Encephalitis in Australia, 1979–2006: trends and aetiologies." Communicable Diseases Intelligence 33 (June 1, 2009): 192–97. https://doi.org/10.33321/cdi2009.33.18.

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The acute encephalitis syndrome has heralded the emergence of multiple virulent pathogens, including Murray Valley encephalitis, Hendra virus and Australian bat lyssavirus, which may result in severe morbidity and mortality. In Australia, encephalitis is not notifiable and there has been no analysis of trends in encephalitis death rates or causation. Australian Bureau of Statistics mortality and population data for the period 1979–2006 were obtained and cause of death data were extracted using ICD-9 (1979–1998) and ICD-10 (1999–2006) codes that included all relevant encephalitis related diagno
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6

Huppatz, Clare, Paul M. Kelly, Christopher Levi, Craig Dalton, David Williams, and David N. Durrheim. "Encephalitis in Australia, 1979–2006: trends and aetiologies." Communicable Diseases Intelligence 33 (June 1, 2009): 192–97. https://doi.org/10.33321/cdi.2009.33.18.

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The acute encephalitis syndrome has heralded the emergence of multiple virulent pathogens, including Murray Valley encephalitis, Hendra virus and Australian bat lyssavirus, which may result in severe morbidity and mortality. In Australia, encephalitis is not notifiable and there has been no analysis of trends in encephalitis death rates or causation. Australian Bureau of Statistics mortality and population data for the period 1979–2006 were obtained and cause of death data were extracted using ICD-9 (1979–1998) and ICD-10 (1999–2006) codes that included all relevant encephalitis related diagno
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7

Ferren, Horvat, and Mathieu. "Measles Encephalitis: Towards New Therapeutics." Viruses 11, no. 11 (2019): 1017. http://dx.doi.org/10.3390/v11111017.

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Measles remains a major cause of morbidity and mortality worldwide among vaccine preventable diseases. Recent decline in vaccination coverage resulted in re-emergence of measles outbreaks. Measles virus (MeV) infection causes an acute systemic disease, associated in certain cases with central nervous system (CNS) infection leading to lethal neurological disease. Early following MeV infection some patients develop acute post-infectious measles encephalitis (APME), which is not associated with direct infection of the brain. MeV can also infect the CNS and cause sub-acute sclerosing panencephalit
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8

Shoukat, Hina, Fahad Pervaiz, Sobia Noreen, Ayesha Khadim, and Maira Latif. "Evaluation of Prevalence of Complications of Measles." Global Pharmaceutical Sciences Review II, no. I (2017): 34–41. http://dx.doi.org/10.31703/gpsr.2017(ii-i).04.

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Study and evaluation of the prevalence of measles and its complication in vaccinated and non- vaccinated patients. To evaluate the prevalence of complications of measles among different age groups of children in the pedriatric ward. Clinical description of a case series. Children of different age groups suffering from measles. We have observed 315 measles patients in the pediatric ward of Bahawal Victoria Hospital in Bahawalpur. They were evaluated on the basis of complications. Different complications were observed in children of different age group and gender, and the main complications were
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9

Aldecoa, Iban, Iván Archilla, Laura Herrero, et al. "Measles inclusion body encephalitis." Clinical Neuropathology 39, no. 07 (2020): 148–51. http://dx.doi.org/10.5414/np301283.

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10

Löve, Arthur, Erling Norrby, and Krister Kristensson. "Measles Encephalitis in Rodents." Journal of Neuropathology and Experimental Neurology 45, no. 3 (1986): 258. http://dx.doi.org/10.1097/00005072-198605000-00009.

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11

Löve, Arthur, Erling Norrby, and Krister Kristensson. "Measles Encephalitis in Rodents." Journal of Neuropathology and Experimental Neurology 45, no. 3 (1986): 258–67. http://dx.doi.org/10.1097/00005072-198605000-00010.

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12

Choubey, Mrigank, J. Debnath, and Biju John. "Acute Measles Encephalitis: Primary Encephalitis or Postinfectious Encephalomyelitis." Journal of Pediatric Neuroradiology 04, no. 03 (2016): 060–63. http://dx.doi.org/10.1055/s-0036-1583523.

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13

Diwan, Mufaddal Najmuddin, Saba Samad, Rabeea Mushtaq, et al. "Measles Induced Encephalitis: Recent Interventions to Overcome the Obstacles Encountered in the Management Amidst the COVID-19 Pandemic." Diseases 10, no. 4 (2022): 104. http://dx.doi.org/10.3390/diseases10040104.

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Encephalitis, a well-known complication of measles, is inflammation of the brain parenchyma which is mostly due to the viral invasion of neurons. It presents with a variety of symptoms ranging from mild to severe depending on the extent of the damaged neurons. The diagnosis is based on clinical symptoms such as fever, headache, altered level of consciousness, focal neurological deficits, etc. A detailed history and physical examination facilitate the diagnosis. Investigations include blood tests for measles-specific antibodies, CT, MRI, and analysis of the CSF. The management of measles-induce
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14

Garg, RavindraK, HardeepS Malhotra, Imran Rizvi, Neeraj Kumar, and Amita Jain. "An unusual case of acute encephalitic syndrome: Is it acute measles encephalitis or subacute sclerosing panencephalitis?" Neurology India 65, no. 6 (2017): 1333. http://dx.doi.org/10.4103/0028-3886.217942.

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15

Stoler, M., B. Meshulam, J. Zoldan, and P. Sirota. "Schizophreniform Episode Following Measles Infection." British Journal of Psychiatry 150, no. 6 (1987): 861–62. http://dx.doi.org/10.1192/bjp.150.6.861.

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A case of schizophreniform episode following measles infection in a 27-year-old woman is presented. The possibility that the clinical picture is a first description in the literature of an association between a schizophreniform episode and possible measles-induced allergic encephalitis is discussed. Other possible connections between measles infection and schizophreniform episode are also mentioned.
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16

Baba, Y., Y. Tsuboi, H. Inoue, T. Yamada, Z. K. Wszolek, and Daniel F. Broderick. "Acute measles encephalitis in adults." Journal of Neurology 253, no. 1 (2005): 121–24. http://dx.doi.org/10.1007/s00415-005-0923-8.

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17

Melenotte, Cléa, Fabien Craighero, Nadine Girard, Philippe Brouqui, and Elisabeth Botelho-Nevers. "Measles encephalitis the return: mild encephalitis with reversible splenial lesion." International Journal of Infectious Diseases 17, no. 1 (2013): e72-e73. http://dx.doi.org/10.1016/j.ijid.2012.11.003.

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Dr, Aqsa Shaheen Dr Fatima Khawer Dr Sana Ijaz. "A RESEARCH STUDY TO DETERMINE THE CAUSE OF MEASLES AND RELATED PROTECTIVE MECHANISMS ALONG WITH RELATED CONSEQUENCES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 05 (2019): 9315–20. https://doi.org/10.5281/zenodo.2715683.

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<strong><em>Background: </em></strong><em>Measles is a disorder commonly present in children. It can be protected by the proper use of vaccination. It can easily transfer from one person to another. It mostly occurred in progressing countries like Pakistan. It can even cause deaths because of its severity. </em> <strong><em>Objective: </em></strong><em>The reasons causing the measles, protective mechanisms of the patients, its severe reactions and consequences were noticed. </em> <strong><em>Material and Methods: </em></strong><em>We carried out this research at Jinnah Hospital, Lahore (March
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19

Lebon, P., G. Ponsot, J. Gony, and J. Hors. "HLA antigens in acute measles encephalitis." Tissue Antigens 27, no. 2 (2008): 75–77. http://dx.doi.org/10.1111/j.1399-0039.1986.tb01501.x.

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20

Lageju, Nimesh, Durga Neupane, Lokesh Shekher Jaiswal, Ashish Kumar Jha, and Roshan Rawat. "A case of measles in a Nepalese child: where are we failing?" International Journal Of Community Medicine And Public Health 9, no. 4 (2022): 1937. http://dx.doi.org/10.18203/2394-6040.ijcmph20220878.

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Measles affected more than 90% of children under 15 years of age and caused 2-3 million measles-associated deaths globally each year before the introduction of vaccines against it. Today, measles vestiges a leading cause of vaccine-preventable illness worldwide, causing more than 100,000 deaths annually. Characterized by a febrile rash illness, measles is often self-resolving. However, significant complications can occur including encephalitis with permanent neurologic sequelae and death in one to three out of 1000 measles cases. Although global measles elimination is a WHO goal, current trend
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21

Bloch, Alan B., Walter A. Orenstein, Harrison C. Stetler, et al. "Health Impact of Measles Vaccination in the United States." Pediatrics 76, no. 4 (1985): 524–32. http://dx.doi.org/10.1542/peds.76.4.524.

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As a result of intensive efforts to vaccinate children, measles and its attendant complications of encephalitis and death have declined more than 99% from the prevaccine era. Similarly, subacute sclerosing panencephalitis has declined markedly. Measles vaccine has been demonstrated to be extremely safe, as well as extremely effective. The health and resource benefits due to vaccination against measles during the first 20 years of vaccine licensure have been enormous. In this period it is estimated that vaccination against measles has prevented 52 million cases, 5,200 deaths, and 17,400 cases o
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22

Kaneko, M., Y. Yamashita, S. Nagamitsu, T. Nakayama, and T. Matsuishi. "Severe Infantile Measles Encephalitis Occurred Three Months after Neonatal Measles." Neuropediatrics 33, no. 5 (2002): 274–77. http://dx.doi.org/10.1055/s-2002-36744.

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23

Ullah, Farid, Taj Muhammad, Farman Ullah, Rida Naz, Bashir Khan, and Shaista Qazi. "Frequency of Measles Related Complications in Hospitalized Children." Pakistan Journal of Medical and Health Sciences 17, no. 1 (2023): 548–50. http://dx.doi.org/10.53350/pjmhs2023171548.

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Background: Measles is a highly contagious viral infection, highly prevalent in children, clinically associated with complications of nervous, respiratory and digestive systems, with significant morbidity and mortality rate in the developing countries. Objectives: The study was aimed to determine the frequency of measles-related complications in hospitalized children. Methods: The study was conducted in tertiary care hospital of District Dera Ismail Khan, from February 2022 to November 2022, including 212 children affected with measles. Results: Most of the affected children (p&lt;0.05) were i
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24

Bouhamed, M., I. Feki, A. Guermazi, F. Guermazi, R. Sallemi, and J. Masmoudi. "Psychiatric manifestations of measles encephalitis: About a case report." European Psychiatry 65, S1 (2022): S875. http://dx.doi.org/10.1192/j.eurpsy.2022.2270.

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Introduction Acute measles encephalitis is a pathology of the central nervous system. It is most frequent in children but can also be described in adults. Given the rarity of this pathology, we present the case of this patient. Objectives present a rare neuropsychiatric complication of measles Methods Présentation d’un cas clinique d’encéphalite rougeoleuse et revue de la littérature Results Mrs. HJ, 45 years old, without any somatic history, was followed for an antisocial personality with a substance use disorder. She consulted the emergency for psychomotor agitation, a fever of 39, and a ras
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Millichap, J. Gordon. "Mumps, Measles and Rubella Vaccination and Encephalitis." Pediatric Neurology Briefs 3, no. 9 (1989): 66. http://dx.doi.org/10.15844/pedneurbriefs-3-9-2.

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26

Croxson, M. C., N. E. Anderson, A. A. Vaughan, et al. "Subacute measles encephalitis in an immunocompetent adult." Journal of Clinical Neuroscience 9, no. 5 (2002): 600–604. http://dx.doi.org/10.1054/jocn.2001.1062.

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27

Fox, Annette, Than Manh Hung, Heiman Wertheim, et al. "Acute Measles Encephalitis in Partially Vaccinated Adults." PLoS ONE 8, no. 8 (2013): e71671. http://dx.doi.org/10.1371/journal.pone.0071671.

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Crowley, S., S. T. al-Jawad, and I. Z. Kovar. "Mumps, measles, and rubella vaccination and encephalitis." BMJ 299, no. 6700 (1989): 660. http://dx.doi.org/10.1136/bmj.299.6700.660.

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Campbell, A. G. "Mumps, measles, and rubella vaccination and encephalitis." BMJ 299, no. 6704 (1989): 916. http://dx.doi.org/10.1136/bmj.299.6704.916.

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Begg, N. T., and N. D. Noah. "Mumps, measles, and rubella vaccination and encephalitis." BMJ 299, no. 6705 (1989): 978. http://dx.doi.org/10.1136/bmj.299.6705.978-b.

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Nalin, D. R. "Mumps, measles, and rubella vaccination and encephalitis." BMJ 299, no. 6709 (1989): 1219. http://dx.doi.org/10.1136/bmj.299.6709.1219-b.

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Lee, K. Y., W. H. Cho, S. H. Kim, H. D. Kim, and I. O. Kim. "Acute encephalitis associated with measles: MRI features." Neuroradiology 45, no. 2 (2002): 100–106. http://dx.doi.org/10.1007/s00234-002-0884-x.

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RATHORE, S. K., B. DWIBEDI, S. K. KAR, S. DIXIT, J. SABAT, and M. PANDA. "Viral aetiology and clinico-epidemiological features of acute encephalitis syndrome in eastern India." Epidemiology and Infection 142, no. 12 (2014): 2514–21. http://dx.doi.org/10.1017/s0950268813003397.

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SUMMARYThis study reports clinico-epidemiological features and viral agents causing acute encephalitis syndrome (AES) in the eastern Indian region through hospital-based case enrolment during April 2011 to July 2012. Blood and CSF samples of 526 AES cases were investigated by serology and/or PCR. Viral aetiology was identified in 91 (17·2%) cases. Herpes simplex virus (HSV; types I or II) was most common (16·1%), followed by measles (2·6%), Japanese encephalitis virus (1·5%), dengue virus (0·57%), varicella zoster virus (0·38%) and enteroviruses (0·19%). Rash, paresis and cranial nerve palsies
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Baczko, K., U. G. Liebert, R. Cattaneo, M. A. Billeter, R. P. Roos, and V. ter Meulen. "Restriction of Measles Virus Gene Expression in Measles Inclusion Body Encephalitis." Journal of Infectious Diseases 158, no. 1 (1988): 144–50. http://dx.doi.org/10.1093/infdis/158.1.144.

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Amy, Ross Russell, Massey Luke, Williams Imogen, et al. "278 Inspector norse." Journal of Neurology, Neurosurgery & Psychiatry 89, no. 10 (2018): A41.1—A41. http://dx.doi.org/10.1136/jnnp-2018-abn.142.

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A 26 year old, Caucasian, female student nurse presented with facial pains and vesicular rash, and over the following three days developed focal faciobrachial twitches. She was febrile, with an erythematous rash. Neurological examination was normal. MRI showed a non-enhancing lesion in the right medulla. CSF was normal with negative viral PCR. EEG demonstrated no seizure activity.A month earlier she was treated with steroids and antibiotics for acute liver injury and maculopapular rash, of presumed allergic aetiology. On that admission, deficiency of Immunoglobulins A and G was noted prompting
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Banik, Gobinda Chandra, Sakib Aman, Farhana Sultana, and Syed Mohammad Arif. "Subacute Sclerosing Panencephalitis." Journal of Bangladesh College of Physicians and Surgeons 37, no. 4 (2019): 205–8. http://dx.doi.org/10.3329/jbcps.v37i4.43352.

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&#x0D; Subacute sclerosing panencephalitis (SSPE) is chronic progressive encephalitis of childhood and young adoloscent due to persistent measles virus infection. This case illustrates a 14 year old girl presented with short history of intellectual decline, abnormal behavior, myoclonus and altered consciousness with suggestive neuroimaging mimicking metachromatic leucodystrophy. Subsequently she was diagnosed to be a case of Subacute sclerosing panencephalitis (SSPE) on the basis of Electroencephalography (EEG) and Cerebrospinal fluid(CSF) measles antibody titer.&#x0D; J Bangladesh Coll Phys S
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WREGHITT, TIM. "7. Neave Kingsbury and the serum prophylaxis of measles Kingsbury AN. J Hyg 1927; 27: 1–13." Epidemiology and Infection 133, S1 (2005): S23—S24. http://dx.doi.org/10.1017/s0950268805004279.

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Measles has been known as a highly contagious serious infection in man for centuries. After a prodromal fever, patients often experience coryza, cough and conjunctivitis followed by a blotchy rash. The disease is more severe in infants and adults with death resulting from encephalitis or pneumonia. Malnourished and immunosuppressed people are also more prone to serious complications and death. Subacute sclerosing panencephalitis (SSPE) is a rare complication, occurring as late sequela several years after measles infection at a rate of 1–5 per million cases.
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Rangkuti, S. M., Nasril Nazir, A. H. Sutanto, Aswin Lubis, and Helena Siregar. "Measles Morbidity and Mortality in the Department of Child Health, Dr. Pirngadi General Hospital, Medan, in 1973-1977." Paediatrica Indonesiana 20, no. 7-8 (2021): 139–44. http://dx.doi.org/10.14238/pi20.7-8.1980.139-44.

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One hundred seventy-six cases with measles have been hospitalized at the Department of Child Health, Dr. Pirngadi General Hospital, Medan in 1973 - 1977.&#x0D; The case fatality rate was 26.1%. The most frequent complications found were Pneumonia, Encephalitis, Diarrhea and Dehydration.&#x0D; Age specific mortality, as expected, was highest in the 0 - 1 year age group (38.6%). A high proportion of the survivors (22.2%) showed recidual signs of brain damage and blind-ness.&#x0D; This study proved that active immunization against measles in Indonesia must have priority.
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McMickle, Robert, Lauren Fryling, and Ross Fleischman. "Acute Demyelinating Encephalomyelitis Following Measles Infection Due to Vaccine Failure: A Case Report." Clinical Practice and Cases in Emergency Medicine 2, no. 5 (2021): 171–73. http://dx.doi.org/10.5811/cpcem.2021.2.49481.

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Introduction: Local outbreaks of measles infection are primarily mediated by international travel of persons from endemic areas, with subsequent spread of the virus via undervaccinated populations. Recent resurgences of measles in communities where vaccination rates are non-ideal secondary to philosophical objections require the emergency physician to more routinely consider the diagnosis. In cases of measles complicated by acute encephalitis or encephalopathy, the diagnosis can be especially difficult to make due to lack of a reliable primary historian. Case report: Here we present a case of
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Ластовка, И. Н., Т. А. Артемчик, and О. Н. Трубчик. "Measles in a Vaccinated Patient." Клиническая инфектология и паразитология, no. 1 (April 16, 2020): 123–28. http://dx.doi.org/10.34883/pi.2020.9.1.011.

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Корь высококонтагиозное, острое вирусное заболевание, которое может привести к та- ким осложнениям, как пневмония, энцефалит, вплоть до летального исхода. В результате вы- сокого охвата 2-дозной вакцинацией против кори в нашем регионе сохраняется относитель- но благоприятная эпидемиологическая ситуация. Регистрация кори в Республике Беларусь связана с завозными случаями из других стран, где корь остается эндемичной. Не исключены в данной ситуации и случаи возникновения кори у иммунизированных пациентов. В статье представлен клинический случай заболевания корью у вакцинированного пациента. Meas
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Muscat, M., S. Glismann, and H. Bang. "Measles in Europe in 2001-2002." Eurosurveillance 8, no. 6 (2003): 123–29. http://dx.doi.org/10.2807/esm.08.06.00414-en.

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A total of 17 928 measles cases were reported to EUVAC.NET in 2001-02, with a 41% increase between the 2 years, giving a crude incidence of 2.36 and 3.37 per 100 000 population respectively. Most reported cases were aged 1-9 years. Outbreak related measles cases amounted to 18% of reported cases in 2001 and 20% in 2002. Less than 1% of cases were known to be imported in 2001 and 2002. Encephalitis as a severe complication was reported in 21 in 2001 and 6 cases 2002. One death attributed to measles was reported in 2001. The proportion of reported cases with known vaccination status increased fr
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Andreula, C. F., G. Marano, and I. Kambas. "Viral Encephalitis." Rivista di Neuroradiologia 10, no. 3 (1997): 357–68. http://dx.doi.org/10.1177/197140099701000308.

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Patients with viral infections of the central nervous system are encountered daily, but it is often difficult to establish a correct differential diagnosis. This paper attempts to “reorganize” our knowledge of such infections. Our starting point was virology, defining the different viruses according to the latest classifications, distinguishing RNA viruses from DNA viruses, assessing capsid shape and dividing each family into genera and species of interest. We then determined the pathophysiology: from initial viraemia we considered the mechanisms of CNS penetration and the pathological changes
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Bankamp, B., U. G. Brinckmann, A. Reich, S. Niewiesk, V. ter Meulen, and U. G. Liebert. "Measles virus nucleocapsid protein protects rats from encephalitis." Journal of Virology 65, no. 4 (1991): 1695–700. http://dx.doi.org/10.1128/jvi.65.4.1695-1700.1991.

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Tidstrøm, Birthe. "COMPLICATIONS IN MEASLES WITH SPECIAL REFERENCE TO ENCEPHALITIS." Acta Medica Scandinavica 184, no. 1-6 (2009): 411–15. http://dx.doi.org/10.1111/j.0954-6820.1968.tb02480.x.

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45

Matsumoto, Yasuyo, Toshiro Shirakawa, Akinobu Gotoh, et al. "Measles encephalitis in early pregnancy and after delivery." Journal of Infection and Chemotherapy 11, no. 2 (2005): 97–100. http://dx.doi.org/10.1007/s10156-005-0372-4.

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46

Schädlich, H. J., A. Karenberg, M. Nekic, and K. Felgenhauer. "Acute encephalitis with intrathecal synthesis of measles antibodies." Journal of Neuroimmunology 20, no. 2-3 (1988): 171–72. http://dx.doi.org/10.1016/0165-5728(88)90155-5.

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Khalifa, M. A., Merlyn M. Rodrigues, Sankaran Rajagopalan, and Peggy Swoveland. "Eye pathology associated with measles encephalitis in hamsters." Archives of Virology 119, no. 3-4 (1991): 165–73. http://dx.doi.org/10.1007/bf01310667.

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Sch�dlich, H. J., A. Karenberg, M. Nekic, and K. Felgenhauer. "Acute encephalitis with intrathecal synthesis of measles antibodies." Journal of Neurology 235, no. 4 (1988): 248–51. http://dx.doi.org/10.1007/bf00314358.

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49

Bitnun, Ari, Patrick Shannon, Andrew Durward, et al. "Measles Inclusion‐Body Encephalitis Caused by the Vaccine Strain of Measles Virus." Clinical Infectious Diseases 29, no. 4 (1999): 855–61. http://dx.doi.org/10.1086/520449.

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50

Hossain, Mohammad Akter, Romal Chowdhury, Nazmul Islam, Md Azharul Hoque, and Md Enayet Hussain. "Adult Onset Subacute Sclerosing Panencephalitis: A case report." Journal of National Institute of Neurosciences Bangladesh 2, no. 1 (2017): 40–42. http://dx.doi.org/10.3329/jninb.v2i1.32970.

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Abstract:
Subacute sclerosing panencephalitis (SSPE) is a chronic encephalitis of childhood and young adolescence due to persistent measles virus infection of the central nervous system (CNS). In majority of cases, onset occurs between 5-10 years of age. SSPE generally occurs 5-10 years after measles virus infection1. The diagnosis of SSPE is based on characteristic clinical and electroencephalogram (EEG) findings, increase measles antibody titer in cerebrospinal fluid (CSF) and serum. As onset of SSPE in adults is rare and may have atypical feature it requires high index of suspicion for early and accu
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