Academic literature on the topic 'Mechanická regulace'

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Journal articles on the topic "Mechanická regulace"

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Swiatlowska, Pamela, Jose L. Sanchez-Alonso, Peter T. Wright, Pavel Novak, and Julia Gorelik. "Microtubules regulate cardiomyocyte transversal Young’s modulus." Proceedings of the National Academy of Sciences 117, no. 6 (January 27, 2020): 2764–66. http://dx.doi.org/10.1073/pnas.1917171117.

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The field of cardiomyocyte mechanobiology is gaining significant attention, due to accumulating evidence concerning the significant role of cellular mechanical effects on the integrated function of the heart. To date, the protein titin has been demonstrated as a major contributor to the cardiomyocytes Young’s modulus (YM). The microtubular network represents another potential regulator of cardiac mechanics. However, the contribution of microtubules (MTs) to the membrane YM is still understudied and has not been interrogated in the context of myocardial infarction (MI) or mechanical loading and unloading. Using nanoscale mechanoscanning ion conductance microscopy, we demonstrate that MTs contribute to cardiomyocyte transverse YM in healthy and pathological states with different mechanical loading. Specifically, we show that posttranslational modifications of MTs have differing effects on cardiomyocyte YM: Acetylation provides flexibility, whereas detyrosination imparts rigidity. Further studies demonstrate that there is no correlation between the total protein amount of acetylated and detyrosinated MT. Yet, in the polymerized-only populations, an increased level of acetylation results in a decline of detyrosinated MTs in an MI model.
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Pan, Xuan Sabrina, Jiewen Li, Edward B. Brown, and Catherine K. Kuo. "Embryo movements regulate tendon mechanical property development." Philosophical Transactions of the Royal Society B: Biological Sciences 373, no. 1759 (September 24, 2018): 20170325. http://dx.doi.org/10.1098/rstb.2017.0325.

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Tendons transmit forces from muscles to bones to enable skeletal motility. During development, tendons begin to bear load at the onset of embryo movements. Using the chick embryo model, this study showed that altered embryo movement frequency led to changes in elastic modulus of calcaneal tendon. In particular, paralysis led to decreased modulus, whereas hypermotility led to increased modulus. Paralysis also led to reductions in activity levels of lysyl oxidase (LOX), an enzyme that we previously showed is required for cross-linking-mediated elaboration of tendon mechanical properties. Additionally, inhibition of LOX activity abrogated hypermotility-induced increases in modulus. Taken together, our findings suggest embryo movements are critical for tendon mechanical property development and implicate LOX in this process. These exciting findings expand current knowledge of how functional tendons form during development and could guide future clinical approaches to treat tendon defects associated with abnormal mechanical loading in utero . This article is part of the Theo Murphy meeting issue ‘Mechanics of development’.
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Ebner, Michael, and Volker Haucke. "Mechanical signals regulate TORC2 activity." Nature Cell Biology 20, no. 9 (August 28, 2018): 994–95. http://dx.doi.org/10.1038/s41556-018-0181-5.

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Cui, Xin, Jie Tong, Jimmy Yau, Apratim Bajpai, Jing Yang, Yansong Peng, Mrinalini Singh, Weiyi Qian, Xiao Ma, and Weiqiang Chen. "Mechanical Forces Regulate Asymmetric Vascular Cell Alignment." Biophysical Journal 119, no. 9 (November 2020): 1771–80. http://dx.doi.org/10.1016/j.bpj.2020.09.020.

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Stamenović, Dimitrije, and Ning Wang. "Invited Review: Engineering approaches to cytoskeletal mechanics." Journal of Applied Physiology 89, no. 5 (November 1, 2000): 2085–90. http://dx.doi.org/10.1152/jappl.2000.89.5.2085.

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An outstanding problem in cell biology is how cells sense mechanical forces and how those forces affect cellular functions. Various biophysical and biochemical mechanisms have been invoked to answer this question. A growing body of evidence indicates that the deformable cytoskeleton (CSK), an intracellular network of interconnected filamentous biopolymers, provides a physical basis for transducing mechanical signals into biochemical signals. Therefore, to understand how mechanical forces regulate cellular functions, it is important to know how cells respond to changes in the CSK force balance and to identify the underlying mechanisms that control transmission of mechanical forces throughout the CSK and bring it to equilibrium. Recent developments of new experimental techniques for measuring cell mechanical properties and novel theoretical models of cellular mechanics make it now possible to identify and quantitate the contributions of various CSK structures to the overall balance of mechanical forces in the cell. This review focuses on engineering approaches that have been used in the past two decades in studies of the mechanics of the CSK.
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Ruehle, M. A., E. A. Eastburn, S. A. LaBelle, L. Krishnan, J. A. Weiss, J. D. Boerckel, L. B. Wood, R. E. Guldberg, and N. J. Willett. "Extracellular matrix compression temporally regulates microvascular angiogenesis." Science Advances 6, no. 34 (August 2020): eabb6351. http://dx.doi.org/10.1126/sciadv.abb6351.

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Mechanical cues influence tissue regeneration, and although vasculature is known to be mechanically sensitive, little is known about the effects of bulk extracellular matrix deformation on the nascent vessel networks found in healing tissues. Previously, we found that dynamic matrix compression in vivo potently regulated revascularization during bone tissue regeneration; however, whether matrix deformations directly regulate angiogenesis remained unknown. Here, we demonstrated that load initiation time, magnitude, and mode all regulate microvascular growth, as well as upstream angiogenic and mechanotransduction signaling pathways. Immediate load initiation inhibited angiogenesis and expression of early sprout tip cell selection genes, while delayed loading enhanced microvascular network formation and upstream signaling pathways. This research provides foundational understanding of how extracellular matrix mechanics regulate angiogenesis and has critical implications for clinical translation of new regenerative medicine therapies and physical rehabilitation strategies designed to enhance revascularization during tissue regeneration.
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Eckes, Beate, Manon C. Zweers, Zhi Gang Zhang, Ralf Hallinger, Cornelia Mauch, Monique Aumailley, and Thomas Krieg. "Mechanical Tension and Integrin α2β1 Regulate Fibroblast Functions." Journal of Investigative Dermatology Symposium Proceedings 11, no. 1 (September 2006): 66–72. http://dx.doi.org/10.1038/sj.jidsymp.5650003.

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Veeriah, Vimal, Riccardo Paone, Suvro Chatterjee, Anna Teti, and Mattia Capulli. "Osteoblasts Regulate Angiogenesis in Response to Mechanical Unloading." Calcified Tissue International 104, no. 3 (November 21, 2018): 344–54. http://dx.doi.org/10.1007/s00223-018-0496-z.

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Barnes, J. Matthew, Laralynne Przybyla, and Valerie M. Weaver. "Tissue mechanics regulate brain development, homeostasis and disease." Journal of Cell Science 130, no. 1 (January 1, 2017): 71–82. http://dx.doi.org/10.1242/jcs.191742.

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Chocholoušek, M., Z. Fulín, and J. Janoušek. "Vývoj autoklávu pro zkoušení materiálù v prostøedí tìžkých tekutých kovù / Development of autoclave for testing materials in the environment of heavy liquid metals." Koroze a ochrana materialu 59, no. 3 (November 1, 2015): 73–76. http://dx.doi.org/10.1515/kom-2015-0017.

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V rámci projektu SUSEN rozšiřuje společnost CVŘ oblast výzkumu na prostředí těžkých tekutých kovů se zaměřením korozního vlivu média na mechanické vlastnosti materiálů. Součástí je vývoj korozních autoklávů pro zkoušení tahových a únavových vlastností a také vlastností v oblasti tečení. Zkušební cela je určena pro zkoušky do teplot 600 °C s regulací obsahu kyslíku v médiu (olovo, eutektikum olovo-bismut). Pro zabezpečení těsnosti a umožnění regulace obsahu kyslíku je v systému udržována ochranná atmosféra argonu s provozním přetlakem do 2 bar. Systém je řešen jako dvoukomorové provedení, kde jedna komora slouží k přípravě korozního média a druhá komora je určena pro materiálové zkoušky. Tavící komora je řešena jako mobilní cela, kterou je možno připojit na další zkušební cely a provést přečerpání média. Zkušební cely jsou umístěny v pracovním prostoru zkušebních strojů a dimenzovány na maximální tahové zatížení 10 kN. Jsou vybaveny adaptéry pro uchycení tyčových vzorků bez závitových hlav a malých CT-vzorků. Navazující činnost bude zaměřena na vývoj měření deformace v tekutých těžkých kovech.
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Dissertations / Theses on the topic "Mechanická regulace"

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Rangharajan, Kaushik Krishna. "Engineering Electromechanical Systems to Regulate Nanoscale Flows." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1524140747281763.

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Hubatsch, Douglas A. "Passive mechanical stimulation regulates expression of acetylcholinesterase in skeletal muscle fibers." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq20923.pdf.

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Schmitt, Benjamin A. "Utility of a Volume-Regulated Drive System for Direct Mechanical Ventricular Actuation." Wright State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=wright1389634127.

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Ibrahim, Michael. "Mechanical load regulates transverse-tubule structure and function in left ventricular cardiomyocytes." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/10486.

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Chronic mechanical load variation triggers a wide range of responses in the heart, a part of which includes cellular remodelling. Over the past 15 years, evidence has amassed that a part of this remodelling process involves changes to a sophisticated structure in the cell membrane, called the transverse (t)-tubule system. The t-tubules are a series of regular membrane invaginations, which contain a high density of ion channels responsible for local Ca2+ induced Ca2+ release (CICR). This thesis addresses the question of whether the t-tubule system can be said to be specifically load sensitive, the nature of that load sensitivity and its molecular regulators. Using surgical models, the influence of mechanical load variation of different durations, degrees and settings are studied. Local CICR and t-tubule structure are investigated. First, it was found that prolonged mechanical unloading induces subtle changes to the t-tubule system, which functionally uncouples the Ryanodine receptors (RyR) and L-type Ca2+ channels (LTCC) and induces a loss of whole cell Ca2+ release synchrony. Second, heart failure was found to be associated with loss of t-tubule structure and Ca2+ handling abnormalities. Following mechanical unloading, the t-tubule system recovered with enhanced LTCC-RyR uncoupling, resulting in improved Ca2+ handling. Third, the t-tubules were found to be unchanged initially during graded mechanical load variation. Prolonged myocardial unloading or overloading impaired t-tubule structure, with loss of normal CICR. Telethonin (Tcap), a member of the cardiomyocyte stretch sensing complex, is a candidate regulator of the t-tubules. In a Tcap knock-out (KO), cardiomyocytes show a primary t-tubule defect, which becomes more pronounced following mechanical overload. These results support the notion that the t-tubule system is dynamically regulated by mechanical overload and unloading, via a molecular pathway including Tcap.
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Elshiekh, Haitham Abdalla. "Maneuvering characteristics in calm water and regular waves for ONR Tumblehome." Thesis, The University of Iowa, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=1560644.

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Standard maneuvering tests were executed at the IIHR wave basin using free-running model. Experiments in calm water as well as wave were performed for a surface combatant with primary focus on establishing a validation benchmark dataset for an unsteady Reynolds-averaged Navier-Stokes (RANS)-based computational fluid dynamics (CFD) code used for computing both air and water flow around a ship. Experimental data from this study will also be used in developing a mathematical model for computing the external forces exerted on the ship model during maneuvering. The geometry is 1/49 scale fully appended ONR Tumblehome model 5613, with a length of 3.147 m. Tests are performed in 20 x 40 x 4.5 m wave basin which is equipped with six plunger-type wave makers, free-running system, as well as carriage tracking system. The maneuvering tests included course keeping, zigzag, and turning tests in head and following waves as well as calm water. Course keeping and zigzag tests were performed at Froude number 0.2 while turning tests were performed at Froude numbers 0.1, 0.2, and 0.3. While the wave height to wavelength ratio was held constant at 0.02 for all the test cases, experiments were performed at three different wavelengths for each Froude number case at different wave encounter angles. Maneuvering trajectories for each test as well as results such as roll, pitch, yaw and yaw rate results were analyzed for all tests. Drift angle, drifting distance, tactical diameter, advance and transfer results from turning tests were obtained and tactical diameter and advance are compared to other facilities data. 1st and 2nd overshoot angles results from zigzag tests and counter rudder angle and speed loss in course keeping were obtained and documented along with the turning test results to help in developing a mathematical model for calculating the forces and moments acting on the ship model and to establish a benchmark data for the CFD validation use.

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Nathanson, Scott Mitchell 1966. "A patient/therapist interactive feedback control system to regulate temperature and control pain in scanned focused ultrasound hyperthermia." Thesis, The University of Arizona, 1992. http://hdl.handle.net/10150/278077.

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An interactive temperature and patient pain feedback controller with manual power control as a function of scan position has been developed and clinically implemented in treating cancerous tumors utilizing the University of Arizona Cancer Center's Scanned Focused Ultrasound Hyperthermia system. The temperature controller implemented uses a Bang-Bang PID controller in 12 adjacent regions. The controller is shown to be able to reduce unwanted hot spots without substantially increasing the size of cold spots in the treatment volume. The addition of patient feedback during treatments has reduced the frequency of undesirable treatment modifications such as moving the scan or lowering of ultrasound power. Patients were able to repeatedly indicate the areas of pain with a pain button during treatments allowing a computer to determine the maximum tolerable power without excessive discomfort.
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Oliveira, Ivan B. (Ivan Borges) 1975. "A "HUM" conjugate gradient algorithm for constrained nonlinear optimal control : terminal and regular problems." Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/89883.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2002.
Includes bibliographical references (p. 145-147).
Optimal control problems often arise in engineering applications when a known desired behavior is to be imposed on a dynamical system. Typically, there is a performance and controller use trade-off that can be quantified as a total cost functional of the state and control histories. Problems stated in such a manner are not required to follow an exact desired behavior, alleviating potential controllability issues. We present a method for solving large deterministic optimal control problems defined by quadratic cost functionals, nonlinear state equations, and box-type constraints on the control variables. The algorithm has been developed so that systems governed by general parabolic partial differential equations can be solved. The problems addressed are of the regulator-terminal type, in which deviations from specified state variable behavior are minimized over the entire trajectory as well as at the final time. The core of the algorithm consists of an extension of the Hilbert Uniqueness Method which, we show, can be considered a statement of the dual. With the definition of a problem-specific inner-product space, a formulation is constructed around a well-conditioned, stable, SPD operator, thus leading to fast rates of convergence when solved by, for instance, a conjugate gradient procedure (denoted here TRCG). Total computational time scales roughly as twice the order of magnitude of the computational cost of a single initial-value problem.
(cont.) Standard logarithmic barrier functions and Newton methods are employed to address the hard constraints on control variables of the type Umin < U < Umax. We have shown that the TRCG algorithm allows for the incorporation of these techniques, and that convergence results maintain advantageous properties found in the standard (linear programming) literature. The TRCG operator is shown to maintain its symmetric positive-definiteness for temporal discretizations, a property that is crucial to the practical implementation of the proposed algorithm. Sample calculations are presented which illustrate the performance of the method when applied to a nonlinear heat transfer problem governed by partial differential equations.
by Ivan B. Oliveira.
Ph.D.
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Xiu-Luan, Bao. "Numerical study of a circular cylinder in regular and random oscillatory flow." Thesis, Manchester Metropolitan University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323642.

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Andersson, Anders G. "Simulations and measurements of free surface flow in regulated rivers." Licentiate thesis, Luleå tekniska universitet, Strömningslära och experimentell mekanik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-18022.

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Open channel flow near hydropower stations is of interest for both engineering and environmental applications. In this research project Computational Fluid Dynamics simulations of free surface flow in regulated rivers were applied with both fish migration and validation of numerical simulations in focus. In the first paper, numerical simulations has been used to evaluate the flow downstream a hydropower plant with regards to upstream migrating fish. Field measurements with an Acoustic Doppler Current Profiler were performed and the measurements were used to validate the simulations. In the second paper ,simulations on the spilling from a dam were performed and compared to experimental results from a physical scale model. The third paper deals with more in depth analysis of field measurements where the variations in the flow downstream a hydropower plant was examined.
Godkänd; 2010; 20101028 (aneane); LICENTIATSEMINARIUM Ämnesområde: Strömningslära/Fluid Mechanics Examinator: Professor Staffan Lundström, Luleå tekniska universitet Diskutant: Teknologie doktor Mats Billstein, Vattenfall Research and Development AB, Älvkarleby Tid: Fredag den 3 december 2010 kl 10.30 Plats: A109, Luleå tekniska universitet
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Rudolf, Katrin. "Hedgehog signaling regulates mechanical tension along the anteroposterior compartment boundary in the developing Drosophila wing." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-150275.

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The interplay between biochemical signals and mechanical processes during animal development is key for the formation of tissues and organs with distinct shapes and functions. An important step during the formation of many tissues is the formation of compartment boundaries which separate cells of different fates and functions. Compartment boundaries are lineage restrictions that are characterized by a straight morphology. Biochemical signaling across compartment boundaries induce the expression of morphogens in the cells along the boundaries. These morphogens then act at long-range to direct growth and patterning of the whole tissue. Compartment boundaries stabilize the position of morphogens and thereby contribute to proper tissue development. The straight morphology of compartment boundaries is challenged by cell rearrangements caused by cell division and tissue reshaping. Physical mechanisms are therefore required to maintain the straight morphology of compartment boundaries. The anteroposterior (A/P) compartment boundary in the developing Drosophila melanogaster wing is established by biochemical signals. Furthermore, mechanical processes are required to maintain the straight shape of the A/P boundary. Recent studies show that mechanical tension mediated by actomyosin motor proteins is increased along the A/P boundary. However, it was not understood how biochemical signals interact with mechanical processes to maintain the A/P boundary. Here I provide the first evidence that Hedgehog signaling regulates mechanical tension along the A/P boundary. I was able to show that differences in Hedgehog (Hh) signal transduction activity between the anterior and posterior compartments are necessary and sufficient to maintain the straight shape of the A/P boundary, which is crucial for patterning and growth of the adult wing. Moreover, differences in Hh signal transduction activity are necessary and sufficient for the increase in mechanical tension along the A/P boundary. In addition, differences in Hh signal transduction activity are sufficient to generate smooth borders and to increase mechanical tension along ectopic interfaces. Furthermore, the differential expression of the transmembrane protein Capricious is sufficient to increase mechanical tension along ectopic interfaces. It was previously suggested that mechanical tension is generated by an actomyosin-cable through which the increase in mechanical tension is transmitted between the junctions along the A/P boundary. Here I show that mechanical tension is generated locally at each cell bond and not transmitted between junctions by an actomyosin cable. My results provide new insights for our understanding of the interplay between biochemical signals and mechanical processes during animal development.
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Books on the topic "Mechanická regulace"

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Landa, Polina S. Regular and Chaotic Oscillations. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001.

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Banakh, Ludmilla, and Mark Kempner. Vibrations of mechanical systems with regular structure. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-03126-7.

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Banakh, Liudmila Ya. Vibrations of mechanical systems with regular structure. Heidelberg: Springer, 2010.

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Gril, Joseph, ed. Wood Science for Conservation of Cultural Heritage – Braga 2008. Florence: Firenze University Press, 2010. http://dx.doi.org/10.36253/978-88-6453-165-6.

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COST Action IE0601 "Wood Science for Conservation of Cultural Heritage" (www.woodculther.org) aims to improve the conservation of European wooden cultural heritage objects, by fostering research and interaction between researchers in various fields of wood science, conservators of wooden artworks, scientists from related fields. These proceedings contain the papers presented in the 2nd International Conference held in Braga (Portugal) 5-7/11/2008, dealing with themes such as material properties, biological degradation, characterization and measurement techniques, conservation, structures. This conference was patronized by the European Society for Wood Mechanics (ESWM), an informal body promoting wood mechanics in Europe by regular organisation of meetings through running COST Actions.
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Hawaii. Legislature. Office of the Legislative Auditor. Sunrise analysis of a proposal to regulate refrigeration and air conditioning mechanics: A report to the Governor and the Legislature of the State of Hawaii. Honolulu: The Auditor, 1994.

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Stechschulte, Nancy Stickels. The Detroit Publishing Company postcards: A handbook for collectors of the Detroit Publishing Company postcards including checklists of the regular numbers, contracts, Harveys, miscellaneous art cards, the 50,000 series, sets, little phostint journeys, mechanical postcards, the panoramas, and many others. Big Rapids, MI: N.S. Stechschulte, 1994.

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Banakh, Ludmilla, and Mark Kempner. Vibrations of mechanical systems with regular structure. Springer, 2012.

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Kempner, Ludmilla Banakh Mark. Vibrations of Mechanical Systems with Regular Structure. Springer, 2010.

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Landa, Polina S. Regular and Chaotic Oscillations (Foundations of Engineering Mechanics). Springer, 2001.

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Mann, Peter. Liouville’s Theorem & Classical Statistical Mechanics. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198822370.003.0020.

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This chapter returns to the discussion of constrained Hamiltonian dynamics, now in the canonical setting, including topics such as regular Lagrangians, constraint surfaces, Hessian conditions and the constrained action principle. The standard approach to Hamiltonian mechanics is to treat all the variables as being independent; in the constrained case, a constraint function links the variables so they are no longer independent. In this chapter, the Dirac–Bergmann theory for singular Lagrangians is developed, using an action-based approach. The chapter then investigates consistency conditions and Dirac’s different types of constraints (i.e. first-class constraints, second-class constraints, primary constraints and secondary constraints) before deriving the Dirac bracket from simple arguments. The Jackiw–Fadeev constraint formulation is then discussed before the chapter closes with the Güler formulation for a constrained Hamilton–Jacobi theory.
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Book chapters on the topic "Mechanická regulace"

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Kaveh, Ali, Hossein Rahami, and Iman Shojaei. "Global Near-Regular Mechanical Systems." In Swift Analysis of Civil Engineering Structures Using Graph Theory Methods, 247–63. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-45549-1_8.

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Gallavotti, Giovanni. "Classical Mechanics and Renormalization Group." In Regular and Chaotic Motions in Dynamic Systems, 185–231. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-1221-5_5.

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Andrianov, I., J. Awrejcewicz, and L. I. Manevitch. "Regular Perturbations of Parameters." In Foundations of Engineering Mechanics, 47–116. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-540-45246-1_2.

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Epstein, Marcelo, and Reuven Segev. "Regular and Singular Dislocations." In Advances in Mechanics and Mathematics, 223–65. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-42683-5_5.

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Duan, Guang-Ren. "Regular Descriptor Linear Systems." In Advances in Mechanics and Mathematics, 57–119. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6397-0_3.

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Rencławowicz, Joanna, and Wojciech M. Zajączkowski. "Local Estimates for Regular Solutions." In Advances in Mathematical Fluid Mechanics, 59–82. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-32330-1_4.

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Gogu, Grigore. "Maximally regular planar parallel robots." In Solid Mechanics and Its Applications, 283–306. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-9831-3_5.

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Banakh, Liudmila Ya, and Mark L. Kempner. "Vibrations of Regular Ribbed Cylindrical Shells." In Foundations of Engineering Mechanics, 209–24. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-03126-7_11.

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Vulfson, Iosif. "Regular Torsional Cyclic Systems with Branched Structure." In Foundations of Engineering Mechanics, 267–80. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-12634-0_9.

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Banakh, Liudmila Ya, and Mark L. Kempner. "Vibrations of Regular Systems with Periodic Structure." In Foundations of Engineering Mechanics, 41–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-03126-7_3.

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Conference papers on the topic "Mechanická regulace"

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Taki, Y., Y. Morita, S. Nishimura, A. Hirata, T. Koga, and E. Nakamachi. "Development of Surface Treatment Technique With Photolytic Macromolecule Including RGDS Peptide." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-66466.

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Arg-Gly-Asp-Ser (RGDS) coating is one of effective methods to improve the cell adhesive property of the scaffold surface. However, it is difficult to regulate the RGDS quantity and distribution, and to visualize RGDS distribution. The purpose of this study was to develop a surface treatment technique that the RGDS quantity can be regulated with the ultraviolet rays irradiation and the RGDS distribution can be visualized with the fluorescence. P(MMA-g-ANP-RGDS) and P(HEMA-g-ANP-RGDS) were respectively synthesized by radical copolymerization of methylmethacrylate (MMA) and 2-hydroxyethylmethacrylate (HEMA) with peptide-macromonomer containing photo-labile linker (3-amino-3-(2-nitrophenyl)propionic acid (ANP)) and RGDS. Each polymer film was produced by using spin-coater, and then ultraviolet rays was irradiated to the each film through the glass mask with three different ultraviolet rays transmissivity of 0 %, 30 % and 60 %. In both polymer films, the RGDS quantity can be regulated by ultraviolet rays irradiation, and the luminance decreased same as the RGDS quantity. Adherent osteoblast-like cells were not observed on P(HEMA-g-ANP-RGDS) film, but the number of adherent osteoblast-like cells was increased with increasing the RGDS quantity on the P(MMA-g-ANP-RGDS) film. In conclusion, we accomplished to develop the surface treatment technique with P(MMA-g-ANP-RGDS) to regulate and visualize the RGDS quantity and distribution.
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Smith, J. L., J. G. Brisson, M. J. Traum, C. Hannon, and J. Gerstmann. "Description of a High-Efficiency Floating-Piston Expander for a Miniature Cryocooler." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33402.

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A cryogenic expander employing low-temperature helium is under development. This expander employs a floating piston operating between a warm variable volume and a cold variable volume to expand the working fluid. The piston’s position is dynamically regulated through an active control routine that actuates electromechanical valves. These valves control helium flow in and out of the variable volumes. Throttling through the warm-end valves regulates the piston’s velocity. The cold-end valves, operating at cryogenic temperatures, are of novel design to achieve system miniaturization and high efficiency at range of operating points.
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Barnes, J. Matthew, Elliot C. Woods, Russell O. Bainer, Yekaterina A. Miroshnikova, Kan Lu, Gabriele Bergers, Carolyn Bertozzi, and Valerie M. Weaver. "Abstract PR05: Glycoprotein-mediated tissue mechanics regulate glioblastoma aggression." In Abstracts: AACR Special Conference: Engineering and Physical Sciences in Oncology; June 25-28, 2016; Boston, MA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.epso16-pr05.

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Lee, Bong Joo, and J. R. Culham. "Effectiveness Analysis of Non-Mechanical Micro-Valvular Conduit in Single Phase Flow." In ASME 2012 10th International Conference on Nanochannels, Microchannels, and Minichannels collocated with the ASME 2012 Heat Transfer Summer Conference and the ASME 2012 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/icnmm2012-73045.

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The non-mechanical valvular conduit, which uses no moving parts but instead relies on a complex geometry to regulate flow, is studied through a combination of numerical, computational and experimental methods. This study is based on using water as the fluid at standard state properties. A numerical model is developed to evaluate the effectiveness of the non-mechanical valve’s intricate geometry. Then computational simulations of the oscillating/pumping sequence of the valvular conduit are conducted to examine the effectiveness of the valve when placed in use for a diaphragm pump. Results demonstrate that the non-mechanical valvular conduit can be an effective application for a diaphragm pump at the micro or macro-scale without requiring valvular mechanics. In computational simulations, when non-mechanical valves are positioned at both the inlet and exit of a diaphragm, the positive circulation of fluid is enhanced by 38% which is sufficient to meet the thermal dissipation requirements of an Intel Pentium D processor (i.e. 130 W). In addition, the experimental results in steady state condition demonstrated that the valvular design regulates the flow direction by producing diodicity (a measure of favorable flow direction) of 2.44.
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Kirui, Gerald K., Learn L. Chiloane, and Yu-Chieh J. Yen. "Remote Mechanical Switch to Regulate Electricity Consumption in a Household." In 2021 Southern African Universities Power Engineering Conference/Robotics and Mechatronics/Pattern Recognition Association of South Africa (SAUPEC/RobMech/PRASA). IEEE, 2021. http://dx.doi.org/10.1109/saupec/robmech/prasa52254.2021.9377208.

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Grubbs, Rachel, Matthew Yough, Olivia Rose, Anthony Lee, Teresa Sicree, Saeed Tiari, and Davide Piovesan. "Temperature Regulated Sleeve for Leg Prosthesis." In ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-10984.

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Abstract This paper presents the findings of the research and design of a heat generating thermal prosthetic sleeve. The goal of the project was to get the sleeve to be designed in a way that keeps a comfortable temperature of the amputation site. Heat transfer analysis as well as comfort tests were used to select the optimal materials for the body of the sleeve. A series of electrical tests using multimeters were used to determine which heating element should be used, as well as in which orientation they should be connected. A microcontroller system had also to be selected to give the sleeve some adjustability.
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Yin, Xiuxing, Xiaofan Li, Vicky Boontanom, and Lei Zuo. "Mechanical Motion Rectifier Based Efficient Power Takeoff for Ocean Wave Energy Harvesting." In ASME 2017 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dscc2017-5198.

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This paper proposes a novel mechanical-motion-rectifier (MMR) based power-takeoff (PTO) for ocean wave energy harvesting. The proposed PTO directly converts irregular oscillatory wave motion into regular unidirectional rotation of the generator. It is mainly composed of two ball screws, three bevel gears, two one-way clutches, and a generator. The two one-way clutches and the bevel gears change the bi-directional rotation of the two ball screws into unidirectional ration of the generator. The MMR rectifies the irregular reciprocating motion into unidirectional rotation; similar to the way the electric voltage rectifier regulates an AC voltage. The proposed PTO can be integrated into a heaving point wave energy converter (WEC). The dynamics and modelling of the PTO are presented. The frequency-domain dynamics of the WEC are then formulated for operating condition and control. The power generation capability of the proposed WEC has been evaluated in MATLAB and WAMIT. The simulation results demonstrate that the power generation capability can be improved by using the MMR method.
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Sundaralingam, Vikneshan, Yogendra Joshi, and Vaibhav Arghode. "Controller to Regulate Maximum Server CPU Temperatures in a Rack by Varying CRAC Supply Air Temperatures." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-87600.

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Conventionally, raised floor data centers operate using controllers that only maintain constant data center space conditions (i.e. supply air temperatures or return air temperatures) at the Computer Room Air Conditioning (CRAC) Unit level with the intention of providing enough cooling for the servers. The objective of this paper is to explore the framework required to design a controller that regulates server CPU temperatures by specifying the supply air temperature of the CRAC. The controller will be an addition to the existing controller used by the CRAC to regulate supply air temperatures. In the discrete-time domain, implementation and the performance of the modified integral action controller is analyzed and other important parameters are compared. As a preliminary attempt, the controller will be designed for a standard 44U cabinet with 42 “1U” servers, where the machines will execute a prescribed compute load variation: (1) step increase in all compute loads and (2) scaled down representation for a rack of servers using utilization trends from one of Google’s data centers. Ultimately, the development of this controller is motivated by the growing interest in Data Center Infrastructure Management (DCIM) where the IT level and facility level information are both used to intelligently plan and manage resources of a data center.
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Kute, Stephanie M., and David A. Vorp. "Regional Association of Biological and Hemodynamic Parameters in Distal End-to-Side Vascular Anastomoses Perfused Ex Vivo." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32513.

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Vascular bypass graft failure is a significant clinical problem and is frequently due to the formation of intimal hyperplasia (IH) [1–3]. IH is characterized by the accumulation of smooth muscle cells (SMC) and extracellular matrix in the intima of the vessel, which occurs when the normal balance between vascular cell proliferation and apoptosis (regulated cell death) is altered [4]. The disturbed flow present at the anastomosis has been implicated in the formation of IH and the link between hemodynamics and graft failure is via a complex cascade of events whereby biomechanical forces cause biological responses [5, 6]. For example, immediate early genes (IEG) such as c-fos, c-jun and egr-1 are involved in the signaling pathways for proliferation and apoptosis. When extracellular biomechanical stimuli (e.g. shear stress) cause the expression of IEG, their protein products translocate to the nucleus. These proteins regulate the expression of a number of genes implicated in cardiovascular disease including growth factors, adhesion molecules, proapoptotic substrates and coagulation factors [7–9]. Because IEG are involved in both proliferation and apoptosis, their expression may upset the normal balance between cell proliferation and apoptosis and could play a vital role in the IH formation in vascular bypass grafts.
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Sun, Yubing, Luis G. Villa-Diaz, Raymond H. W. Lam, Weiqiang Chen, Paul H. Krebsbach, and Jianping Fu. "Investigation of Mechanoresponsive Behaviors of Human Embryonic Stem Cells Using Microfabricated Elastomeric Post Arrays." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80269.

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Much effort has been recently directed to investigate how soluble factors in the local cellular microenvironment of embryonic stem cells (ESCs) regulate their fate decisions [1]; however, effects of mechanical signals in the local cellular microenvironment on the fates of ESCs are still not yet well understood. Early experimental evidence established in recent years has shown that mechanical signals and external forces experienced through interactions with extracellular matrix (ECM) mechanics can play critical roles in regulating survival, proliferation and differentiation of ESCs. However, there is still limited knowledge of how mechanical signals in the local cellular microenvironment regulate the fate decisions of human ESCs (hESCs), and advancing such knowledge will be critical for both fundamental understanding and clinical applications of hESCs. This work was thus set to explicitly investigate the mechanosensitive properties of hESCs.
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Reports on the topic "Mechanická regulace"

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Godenau, Dirk. Migration and the economy. Observatorio de la Inmigración de Tenerife. Departamento de Geografía e Historia. Universidad de La Laguna. Tenerife, 2020. http://dx.doi.org/10.25145/r.obitfact.2020.02.

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Economic reasons are among the basic explanatory factors of migration, whether international or internally within a country. In turn, migratory movements have effects on the economy in terms of economic growth in general, but also in the different markets (work, housing, consumer goods, etc.) and public services (education, health, social services, etc.). The purpose of this document is to offer an overview of these interactions between migration and the economy in the case of the Canary Islands. To do this, certain conceptual clarifications will be made initially involving the mutual determination of both processes, before later providing specifics with evidence on the Canarian case for the main issues considered: the economic reasons for migration, and its impact on economic growth, the labour market and the living conditions of the immigrant population. The final section alludes to the importance of the institutional framework that regulates these relations between migration and the economy, which are far from being interpretable as a mechanical relationship and isolated from the political sphere.
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