Academic literature on the topic 'Mechanism of action of drugs'

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Journal articles on the topic "Mechanism of action of drugs"

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Edwards, David I. "Nitroimidazole drugs-action and resistance mechanisms I. Mechanism of action." Journal of Antimicrobial Chemotherapy 31, no. 1 (1993): 9–20. http://dx.doi.org/10.1093/jac/31.1.9.

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Luciani, S., S. Bova, and G. Cargnelli. "Mechanism of action of antihypertensive drugs." Pharmacological Research 22 (September 1990): 278. http://dx.doi.org/10.1016/s1043-6618(09)80309-5.

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Yaqub, Farhat. "Mechanism of action of anthracycline drugs." Lancet Oncology 14, no. 8 (2013): e296. http://dx.doi.org/10.1016/s1470-2045(13)70118-9.

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Nakashima, Shigeru. "Mechanism of Action of Anti-Fungal Drugs." Nippon Ishinkin Gakkai Zasshi 40, no. 3 (1999): 119–23. http://dx.doi.org/10.3314/jjmm.40.119.

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Vane, J. R., and R. M. Botting. "Mechanism of Action of Anti-Inflammatory Drugs." Scandinavian Journal of Rheumatology 25, sup102 (1996): 9–21. http://dx.doi.org/10.3109/03009749609097226.

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Pleuvry, Barbara J. "Mechanism of action of general anaesthetic drugs." Anaesthesia & Intensive Care Medicine 5, no. 10 (2004): 352–53. http://dx.doi.org/10.1383/anes.5.10.352.52309.

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Vane, John R., and Renia M. Botting. "Mechanism of action of aspirin-like drugs." Seminars in Arthritis and Rheumatism 26 (June 1997): 2–10. http://dx.doi.org/10.1016/s0049-0172(97)80046-7.

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Samanin, Rosario, and Silvio Garattini. "Neurochemical Mechanism of Action of Anorectic Drugs." Pharmacology & Toxicology 73, no. 2 (1993): 63–68. http://dx.doi.org/10.1111/j.1600-0773.1993.tb01537.x.

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Pleuvry, Barbara J. "Mechanism of action of general anaesthetic drugs." Anaesthesia & Intensive Care Medicine 9, no. 4 (2008): 152–53. http://dx.doi.org/10.1016/j.mpaic.2007.08.004.

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Best, Sabine L., and Peter J. Sadler. "Gold drugs: Mechanism of action and toxicity." Gold Bulletin 29, no. 3 (1996): 87–93. http://dx.doi.org/10.1007/bf03214741.

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Dissertations / Theses on the topic "Mechanism of action of drugs"

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Matkar, Smita S. "Mechanism of action of potential anticancer drugs." Scholarly Commons, 2008. https://scholarlycommons.pacific.edu/uop_etds/2368.

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Traditionally, inoperable or metastatic cancers have been treated by causing massive DNA damage in order to induce self-destruction (apoptosis) of the rapidly multiplying cancer cells. Initially, this strategy works for many cancers, in particular those which express normal p53 tumor suppressor protein. However, most cancers eventually aquire mutations in either p53 or other signaling molecules and fail to initiate apoptosis in response to severe DNA damage. During this study three types of compounds were investigated for their DNA damaging and anticancer effects: a pair of novel metal contain
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Kelland, Lloyd R. "Antitumour and mechanism of action studies with novel cancer drugs." Thesis, University of Bath, 2000. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760737.

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Beverly, Bart J. "Mechanism of action of aurothioalkyl antiarthritic drugs : role of myeloproxidase /." The Ohio State University, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487330761219101.

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Elayadi, Anissa N. "Metabolism and mechanism of action of acylfulvenes, novel antitumor drugs /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1999. http://wwwlib.umi.com/cr/ucsd/fullcit?p9952666.

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CONSONNI, ELISA. "Anticancer drugs mechanism of action investigated by advanced biomolecular tools." Doctoral thesis, Università degli Studi di Milano, 2005. http://hdl.handle.net/2434/61944.

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Pixantrone (BBR2778), a DNA intercalating agent topoisomerase II inhibitor, belongs to the aza-anthracenedione chemical class and is currently under clinical investigation in non-dgkn iymphomas (NHLs)
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Christie, Andrew W. "Mechanism of action of selected anti-lipolytic agents in adipocytes." Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282761.

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Chen, Yu. "Mechanism of action of platinum anticancer drugs : from kinetic to structural studies." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/14521.

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Cisplatin, <I>cis</I>-[Pt(NH<SUB>3</SUB>)<SUB>2</SUB>Cl<SUB>2</SUB>], has been a successful and most widely used anticancer drug since its first discovery 30 years ago. Up to now the mechanism of action of this drug is still not well understood. In this thesis, pH dependent platinum-sulfur interactions, the solution structure of cisplatin DNA GpG intrastrand adduct and the chemistry of a new anticancer active drug have been investigated. Using [<SUP>1</SUP>H, <SUP>15</SUP>N] 2D NMR spectroscopy and HPLC, together with <SUP>15</SUP>N-labelled amine ligands highly pH dependent interconversion be
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Di, Daniel Elena. "Mechanisms of action of mood-stabilizing drugs." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1445413/.

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Bipolar disorder or manic-depression is a severe and common psychiatric illness that is often treated with mood-stabilizing drugs. Several molecular targets and signalling pathways have been implicated in the pathophysiology of the illness and in the mechanism of action of these drugs. However, the precise targets that are responsible for the therapeutic action and side-effects of the drugs are not known. In this PhD thesis we have analysed some of the potential drug targets, in particular extracellular signal-regulated kinase mitogen-activated protein kinase (ERK/MAPK) and glycogen synthase k
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Chan, Wing Chi. "Chemical studies on mechanism of action of the Chinese antimalarial artemisinin and its derivatives /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?CHEM%202005%20CHAN.

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Teran, Claudia. "Efficacy and Mechanism of Action of a Novel Class of Antic-Cancer Drugs." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34412.

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The incidence of cancer worldwide has increased over the years, and gastrointestinal cancers (G.I.) are amongst the most common forms of cancer. Nevertheless, there is still no curative treatments for this group of tumors. Nucleoside analogues are widely used in cancer treatment. The prevailing compounds are Gemcitabine (used for pancreatic cancer and other carcinomas), 5-Fluorouracil (used in breast, colon, and other cancers), Cytarabine and Clofarabine (used in leukemias). Gemcitabine, the current standard of care for various forms of solid tumors, has a limited efficacy against pancreatic c
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Books on the topic "Mechanism of action of drugs"

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White, H. Steve. Mechanisms of action of antiepileptic drugs. Professional Communications, Inc., 2010.

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Woo, Junghoon. Interrogating Drug Mechanism of Action Using Network Dysregulation Analysis. [publisher not identified], 2015.

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V, Trach, ed. Specific heart rate reducing effect of UL-FS 49 Cl: Electrophysiological mechanism of action. Universitätsverlag Ulm, 1991.

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Ryall, Ronald W. Mechanisms of drug action on the nervous system. 2nd ed. Cambridge University Press, 1989.

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M, Eckert George, Gutmann Felix 1908-, and Keyzer Hendrik, eds. Electropharmacology. CRC Press, 1990.

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Woodman, David D. Laboratory animal endocrinology: Hormonal action, control mechanisms, and interactions with drugs. John Wiley & Sons, 1997.

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D, Korchagin A., Federalʹnai͡a︡ t͡s︡elevai͡a︡ programma "Kulʹtura Rossii." Podprogramma "Podderzhka poligrafii i knigoizdanii͡a︡ Rossii.", and Russia (Federation), eds. Kommentariĭ k Patentnomu zakonu Rossiĭskoĭ Federat͡s︡ii. Izd-vo "Kompanii͡a︡ Dimitreĭd Grafik Grupp", 2004.

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M, Kasumov Kh. Struktura i membrannai︠a︡ funkt︠s︡ii︠a︡ polienovykh makrolidnykh antibiotikov. Nauka, 2009.

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1937-, Kanno Morio, and Hattori Yuichi, eds. Current aspects of cellular and subcellular mechanism of drug actions. Hokkaido University School of Medicine, 2000.

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L, Faingold Carl, and Fromm Gerhard H, eds. Drugs for control of epilepsy: Actions on neuronal networks involved in seizure disorders. CRC Press, 1992.

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Book chapters on the topic "Mechanism of action of drugs"

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Mennini, T., S. Caccia, and S. Garattini. "Mechanism of action of anxiolytic drugs." In Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des recherches pharmaceutiques. Birkhäuser Basel, 1987. http://dx.doi.org/10.1007/978-3-0348-9289-6_10.

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Hondeghem, Luc M., and Bertram G. Katzung. "Mechanism of Action of Antiarrhythmic Drugs." In Physiology and Pathophysiology of the Heart. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-0873-7_24.

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Pascal, M., H. Cao Danh, and C. Legendre. "Mechanism of Action of Fenofibrate: New Data." In Drugs Affecting Lipid Metabolism. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71702-4_59.

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Fitzpatrick, F. A. "Formation and Mechanism of Action of Epoxyeicosatrienoic Acids." In Prostanoids and Drugs. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-7938-6_4.

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Leonard, B. E. "Antidepressant Drugs." In Mechanisms of Drug Action. Palgrave Macmillan UK, 1986. http://dx.doi.org/10.1007/978-1-349-08026-7_6.

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Vane, John R., and Regina M. Botting. "Mechanism of Action of Anti-Inflammatory Drugs." In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4899-1810-9_27.

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Ahmed, Muhammad Zeeshan, Tazeen Rao, Ali Saeed, et al. "Antifungal Drugs: Mechanism of Action and Resistance." In Biochemistry of Drug Resistance. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-76320-6_5.

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McCombe, Kate, and Lara Wijayasiri. "Mechanism of Drug Action." In The Primary FRCA Structured Oral Examination Study Guide 2, 3rd ed. CRC Press, 2025. https://doi.org/10.1201/9781003276470-3.

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Vane, J. R. "The Mechanism of Action of Anti-Inflammatory Drugs." In Advances in Eicosanoid Research. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-662-04047-8_1.

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Chakraborty, Dipesh. "Pharmacodynamics: Mechanism of Drug Action." In Essentials of Pharmacodynamics and Drug Action. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-2776-6_2.

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Conference papers on the topic "Mechanism of action of drugs"

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Calcagno, Daniele, Marco De Marco, Marco Palombo, Marco Zabbia, and Elisa Ferrari. "Environmental Assisted Cracking (EAC) of Steel Pressure Vessel in Boiler Water Service: Case Histories, Damage Mechanism Considerations, Design and Fabrication." In CORROSION 2015. NACE International, 2015. https://doi.org/10.5006/c2015-05431.

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Abstract This paper is inspired by a series of failures that occurred in steam drums and deareators in power generation and chemical/petrochemical plants. In each case the failure occurred in non-Post Weld Heat Treated (PWHT) carbon steel (CS) and low alloy steel (LAS) welded joints and was related to the synergic action of the mechanical stresses and the chemical environment (boiler and feed water). Although technical literature has already covered and discussed the topic and the Users have experienced such damage for a long time, the primary mechanism and root causes of the failure events ar
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Kurtoğlu, Gazi Levent. "Anti-Drug Supply Policies: Inter-institutional Coordination and Action Plans." In Panel on "Effective Drug Control Strategies in Northern Cyprus: Challenges and Opportunities in 2024". Emanate Publishing House Ltd., 2024. http://dx.doi.org/10.70020/ehass.2024.7.6.

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Türkiye has been developing strategic plans and related action plans to fight addictions including drugs since 2006. The responsibility for nationwide coordination is under the jurisdiction of the Department of Combating Tobacco and Substance Addiction in the Ministry of Health. This paper focuses on four research objectives: firstly, the inter-institutional coordination mechanisms in place for combating drug supply in Türkiye; secondly, the National Strategy Documents and Action Plans in the fight against drugs developed and implemented so far in Türkiye; and thirdly, the contents of the Acti
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Cunha, Bernardo, Luis Fonseca, and Cecilia Calado. "High-throughput bioassay for mechanism of action determination of antibacterial drugs." In 2017 IEEE 5th Portuguese Meeting on Bioengineering (ENBENG). IEEE, 2017. http://dx.doi.org/10.1109/enbeng.2017.7889478.

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Dun, Matthew D., Amanda M. Smith, Richard G. S. Kahl, et al. "Abstract 2038: Unraveling the mechanism of action: drugs that activate the tumor suppressor 2A ." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2038.

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Fedoros, E. I., G. A. Badun, I. D. Grozdova, et al. "Novel polyphenolic ligand of BP-Cx family drugs: cell distribution and mechanism of action." In Fifth International Conference of CIS IHSS on Humic Innovative Technologies «Humic substances and living systems». CLUB PRINT ltd., 2019. http://dx.doi.org/10.36291/hit.2019.fedoros.089.

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Moore, Zachary, Gaurab Chakrabarti, Costas Lyssiotis, Ralph Deberardinis, and Boothman A. David. "Abstract B47: Modulating the NQO1-dependent ‘kiss of death’ mechanism of action of NQO1 bioactivatable drugs." In Abstracts: AACR Special Conference on Pancreatic Cancer: Innovations in Research and Treatment; May 18-21, 2014; New Orleans, LA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.panca2014-b47.

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Buczko, W., M. Pietraszek, E. Chabielska, and B. Malinowska. "THE INFLUENCE OF SOME HYPOTENSIVE DRUGS ON THE SEROTONERGIC MECHANISMS IN RATS PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643440.

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Serotonin (5HT) is a vasoactive amine that has been reported to be involved in a number of forms of circulatory failure. The 5HT content and metabolism in platelets is changed in hypertension and in peripheral arteriolar diseases. The present study concerns the effect of verapamil (VER), propranolol (PRO) and cap-topril (CAP) - drugs having different hypotensive mechanisms of action, on serotonergic mechanisms in rat blood platelets. In vitro, VER produced noncompetitive inhibition of 14C-5HT uptake (IC50=8.2μM), PRO inhibited the uptake in a competitive fashion (Km =0.9μM), whereas CAP was in
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Ponamarev, V. S. "Some nuclear receptors as application points for drugs with hepatotropic activity." In SPbVetScience. FSBEI HE St. Petersburg SUVM, 2023. http://dx.doi.org/10.52419/3006-2023-8-51-56.

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At present, one of the most promising directions in the search for chemical compounds-candidates for drugs is the fundamental study of signaling molecules, whose main function is to transmit information to the cell through ion channels and nuclear receptors associated with G-protein or with enzymatic activity. One of the fundamental tasks of modern pharmacology - the expansion of the range of hepatotropic drugs with a fundamentally new mechanism of action - is currently being actively solved, including through specific chemical compounds that act on cell nuclear receptors, one of which is obet
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Zhao, Jie, Aiyu Wang, Fangfang Su, Yanyan Chen, and Honghai Feng. "Construction of knowledge graph of drug-action mechanism." In 2021 3rd International Conference on Advances in Computer Technology, Information Science and Communication (CTISC). IEEE, 2021. http://dx.doi.org/10.1109/ctisc52352.2021.00038.

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Alhaj, Fatima, Duha Qutishat, Heba Al Harahsheh, Nadim Obeid, and Bassam Hammo. "Detecting DDI Using Ontology: Drug Mechanism of Action." In 2019 IEEE Jordan International Joint Conference on Electrical Engineering and Information Technology (JEEIT). IEEE, 2019. http://dx.doi.org/10.1109/jeeit.2019.8717527.

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Reports on the topic "Mechanism of action of drugs"

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Macedo, Luciana, and Linda Malkas. The Human Breast Cancer DNA Synthesome Can Serve as a Novel In Vitro Model System for Studying the Mechanism of Action of Anticancer Drugs. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada393926.

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Jiang, Haiyan. The Human Breast Cancer Cell DNA Synthesome Can Serve as a Novel in Vitro Model System for Studying the Mechanism of Action of Anticancer Drugs. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada384124.

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Moza, Andreea, Florentina Duica, Panagiotis Antoniadis, et al. Outcome of newborns in case of SARS-CoV-2 vertical infection. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.12.0093.

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Review question / Objective: To identify the types and examine the range of available evidence of vertical transmission of SARS-CoV-2 from mother to newborn. To clarify the key concepts and criteria for diagnosis of SARS-CoV-2 vertical infection in neonates. To summarize the existing evidence and advance the awareness on SARS-CoV-2 vertical infection in pregnancy. Background: Severe Acute Respiratory Syndrome Virus 2 (SARS-CoV-2), the virus that causes 2019 coronavirus disease (COVID-19), has been isolated from various tissues and body fluids, including the placenta, amniotic fluid, and umbili
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Roberts, Jr, and Charles T. A Novel Mechanism of Androgen Receptor Action. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada489364.

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Roberts, Jr, and Charles T. A Novel Mechanism of Androgen Receptor Action. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada503252.

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Bates, Paula J. Mechanism of Action of Novel Antiproliferative Oligonucleotides. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada406133.

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Roberts, Jr, and Charles T. A Novel Mechanism of Androgen Receptor Action. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada466168.

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Kamasani, Uma R., and George Prendergast. Mechanism of RhoB/FTI Action in Breast Cancer. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada446332.

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Rane, Neena S., and George C. Prendergast. Mechanism of RhoB/FTI Action in Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada412302.

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Rogers, Terry B. Mechanism of Action of the Presynaptic Neurotoxin, Tetanus Toxin. Defense Technical Information Center, 1991. http://dx.doi.org/10.21236/ada246780.

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