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Dissertations / Theses on the topic 'Mechanism of infection'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Fernandes, Isabel Oliveira. "Infection mechanism of Diplodia corticola." Doctoral thesis, Universidade de Aveiro, 2015. http://hdl.handle.net/10773/15487.

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Doutoramento em Biologia<br>Diplodia corticola is regarded as the most virulent fungus involved in cork oak decline, being able to infect not only Quercus species (mainly Q. suber and Q. ilex), but also grapevines (Vitis vinifera) and eucalypts (Eucalyptus sp.). This endophytic fungus is also a pathogen whose virulence usually manifests with the onset of plant stress. Considering that the infection normally culminates in host death, there is a growing ecologic and socio-economic concern about D. corticola propagation. The molecular mechanisms of infection are hitherto largely unknown. Accordi

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2

Shammakhi, Sahar. "The Infection and Uncoating Mechanism of the Giant Melbournevirus." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-428745.

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Since their 'discovery' at the turn of the 21st century, giant viruses of the amoeba have captured the fascination of virologists. They have raised a plethora of questions regarding their evolution and ecological significance and have greatly defied a century's old definition of viruses. By now, it is understood that a handful of giant viruses enter the amoeba via the phagosomal pathway. This thesis chooses to focus on the giant Melbournevirus (MelV) regarding its entry and uncoating pathway. We now conclude that the initial attachment between MelV and amoeba cells is built upon glycan interac

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3

Charsou, Chara. "Autophagy as a control mechanism in human papilloma virus infection." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/25878.

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Human Papilloma Virus (HPV) is a conserved DNA virus, which infects mucosal and cutaneous epithelia. Although over 200 types of HPV have been identified which can infect humans, only around 15 high-risk (HR) types have been shown to be responsible for the development of cancer. HPV-16 is the most abundant HR-HPV type being responsible for almost 70% of cervical cancers. HPV-16 consists of 8 genes, the early genes (E1, E2, E4, E5 and the potential oncogenes E6 and E7) responsible for the infection, amplification and proliferation and the late genes (L1 and L2) responsible for the packaging and

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4

Scala, Carlo. "Mechanism of DC-SIGN mediated enhancement of HIV-1 infection." Thesis, King's College London (University of London), 2015. http://kclpure.kcl.ac.uk/portal/en/theses/mechanism-of-dcsign-mediated-enhancement-of-hiv1-infection(1cf4fa70-8144-4828-810c-e28900c962bb).html.

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This thesis describes an investigation of the mechanisms by which DC-SIGN mediates enhancement of HIV-1 infection. Mannose-binding C-type lectin receptors, expressed on Langerhans cells and subepithelial dendritic cells (DCs), play an important role in HIV-1capture and subsequent dissemination to lymph nodes. DC-SIGN mediates both productive infection of DCs and trans-infection of CD4+ T cells that occurs in the absence of replication. The molecular events involved in transmission have not been fully defined. In this study, surface plasmon resonance analyses demonstrated that DC-SIGN, but not

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Mitchell, Peter James. "Inappropriate Regulation as a Mechanism for Persistence of Helicobacter Pylori Infection." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486573.

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6

Ogbechi, J. "Investigating the mechanism behind the tissue necrosis in Mycobacterium ulcerans infection." Thesis, University of Surrey, 2017. http://epubs.surrey.ac.uk/813238/.

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Buruli ulcer (BU) is a progressive necrotising skin disease caused by Mycobacterium ulcerans. The bacteria produce a lipid virulence factor, mycolactone which is responsible for the tissue necrosis seen in the disease but the trigger for this is not known. Endothelial cells play a critical role in maintaining tissue homeostasis but prior to this thesis, the effect of mycolactone on endothelial cells had not been investigated. Mycolactone caused a reduction in the expression of proteins involved in the regulation of clotting as well as adhesion molecules in endothelial cells. The mycolactone-me

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7

Asakura, Makoto. "Studies on metabolic function required for infection mechanism of Colletotrichum lagenarium." Kyoto University, 2007. http://hdl.handle.net/2433/136577.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第13454号<br>農博第1665号<br>新制||農||949(附属図書館)<br>学位論文||H19||N4310(農学部図書室)<br>UT51-2007-S485<br>京都大学大学院農学研究科応用生物科学専攻<br>(主査)教授奥野哲郎, 教授遠藤隆, 准教授田中千尋<br>学位規則第4条第1項該当

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Sneyd, Hannah, and Hannah Sneyd. "Influenza A: Mechanism of Infection and Development of M2 Ion Channel Inhibitors." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/626385.

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Influenza viral infection causes several hospitalizations and claims the lives of many people each year. The threat of epidemic and pandemic are more pressing than ever with newly mutated strains developing every year. Understanding the mechanism of infection of influenza can help identify new potential drug targets and help progress the development of antivirals. Currently there are two classes of FDA approved drugs, neuraminidase inhibitors and M2 ion channel inhibitors, to combat influenza infection. Unfortunately, viral resistance to M2 ion channel blockers has caused them to stop being us

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Sundaravaradan, Vasudha. "Molecular Mechanism of HIV-1 Infection: Role of Viral and Host Determinants." Diss., Tucson, Arizona : University of Arizona, 2006. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1685%5F1%5Fm.pdf&type=application/pdf.

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10

Leung, Hiu-lan Nancy, and 梁曉灡. "Mechanism of antibody-dependent enhancement in severe acute respiratory syndrome coronavirus infection." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B47327066.

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Severe lymphopenia is a clinical feature of Severe Acute Respiratory Syndrome (SARS) patients. However, lymphocytes do not express receptor for SARS-CoV, neither the widely accepted viral receptor angiotensin converting enzyme 2 (ACE2) nor the putative receptors Dendritic Cell- and Liver/lymph-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin (DC-SIGN and L-SIGN). Our group previously showed in vitro that, SARS-CoV Spike pseudotyped particles (SARSCoVpp) could infect human B cells only when inoculated in presence of anti-SARSCoV Spike immune serum. Such observations rais

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11

Permanyer, Bosser Marc. "Characterization of the infection mechanism during cell-to-cell transmission of HIV-1." Doctoral thesis, Universitat Autònoma de Barcelona, 2013. http://hdl.handle.net/10803/129101.

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La transmissió cèl·lula a cèl·lula del VIH-1 és un mecanisme altament eficient de disseminació viral, i la seva rellevància durant la difusió in vivo en els llocs actius de replicació, és a dir, en els teixits limfoides primaris i secundaris, sembla probable. La transmissió d'antígens del VIH de cèl·lules infectades a cèl·lules T CD4+ no infectades es produeix a través de contactes cèl·lula a cèl·lula que requereixen exclusivament de la interacció entre la proteïna de l'embolcall del VIH gp120 i el receptor CD4 per induir la captació endocítica de partícules virals en compartiments resistents

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Carvalho, Ana Teresa Carrilho. "The mechanism of the Legionella VipA protein in altering actin dynamics during infection." Master's thesis, Universidade Nova de Lisboa, Instituto de Tecnologiaa Química e Biológica António Xavier, 2019. http://hdl.handle.net/10362/120872.

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Dissertation presented to obtain the Master Degree in Biochemistry for Health<br>"Legionella pneumophila is a facultative intracellular bacterium that is commonly found in fresh water and soils, parasitizing a wide range of protozoa hosts. Co-evolution mechanisms allowed this bacterium to parasitize other phagocytic cells and rendered it the ability to become a potential human pathogen. For instance, after inhalation of contaminated aerosols by the host, it can survive and replicate inside human macrophages in the lungs by creating a specialized phagosome that is not degraded, possibly resulti

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Van, den Boogaart Tom. "The mechanism of replicase-derived resistance to pea early browning virus and pea seed-borne mosaic virus." Thesis, University of East Anglia, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327603.

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Feagins, Alicia R. "Foodborne Transmission and Molecular Mechanism of Cross-species Infection of Hepatitis E Virus (HEV)." Diss., Virginia Tech, 2010. http://hdl.handle.net/10919/77266.

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Hepatitis E virus (HEV), the causative agent of hepatitis E, is an emerging virus of global distribution. At least four distinct genotypes of HEV exist worldwide: genotype 1 and 2 HEV strains are responsible for waterborne epidemics; genotype 3 and 4 HEV strains are responsible for sporadic occurrences of acute hepatitis E. Genotype 3 and 4 HEVs are zoonotic and have a more expanded host range than genotypes 1 and 2 which are restricted to humans. Genotype 3 and 4 HEV isolates obtained from animal tissues are genetically very similar, or identical in some cases, to human HEV recovered from hep

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15

Smith, Alexia Genese Beck Melinda A. "Obesity alters the immune response to influenza virus infection a mechanism for immune modulation /." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1606.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2008.<br>Title from electronic title page (viewed Sep. 16, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Nutrition, School of Public Health." Discipline: Nutrition; Department/School: Public Health.

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Klein, de Licona Hannah Washington. "Congenital LCMV virus: mechanism of brain disease in a rat model of congenital viral infection." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/531.

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Lymphocytic choriomeningitis virus (LCMV) infection during pregnancy severely injures the human fetal brain. Neonatal rats inoculated with LCMV are an excellent model of congenital LCMV infection, as they develop neuropathology, including cerebellar injuries, similar to those seen in humans. The goal of this thesis was to determine what underlies brain injury and the differential immune response and to determine the role of T-cells in LCMV induced pathology. First, I examined whether cytokine and chemokine expression after LCMV infection was higher in the cerebellum and olfactory bulbs, which

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Phan, Michael. "Viral Sensitizers Potentiate the Infection of Cancer Cells Via NF-kB." Thesis, Université d'Ottawa / University of Ottawa, 2020. http://hdl.handle.net/10393/40524.

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Genetically engineered oncolytic viruses (OVs) have been proven to be effective anti-cancer agents. However, the heterogeneity of tumours and obligate attenuation of OVs to achieve safety can limit their efficacy. Our lab has previously shown that diverse small molecules, which we have termed “Viral Sensitizers”, used in combination with OVs can potentiate the infection of cancer cells by OVs over 1000-fold in some cases, resulting in cancer-specific killing in both in vitro and in vivo tumour models. We observed that a subset of viral sensitizer compounds ultimately acts by reducing the expre

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18

Deng, L. W. "Infection mechanism of filamentous bacteriophage fd : interaction between E. coli F-pilus and phage protein pIII." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598493.

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Gene 3 protein (pIII), a minor coat protein located at one end of the filamentous bacteriophage fd, is involved in initiating the infection by the virus of <I>Escherichia coli</I> cells that display an F-pilus. An introduction and the experimental materials and methods are described in Chapters 1 and 2, respectively. Chapter 3 describes the construction and expression of the N-terminal di-domain and individual domains of pIII protein. The plaque-forming assay <I>in vivo</I> was used to investigate the ability of the isolated pIII domains to interact with F-pilus. Chapter 4 presents the investi

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Münter, Sylvia Gabriele. "Analysing the role of a cellular mechanism in HIV infection and evaluation of novel antiviral compounds." Paris 11, 2004. http://www.theses.fr/2004PA112103.

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VIH est responsable du syndrome d'immunodéficience acquise (SIDA). L'étape fondamentale pour découvrir de nouvelles stratégies antivirales reste la compréhension de la pathogénie du SIDA ainsi que les mécanismes moléculaires de l'interaction du virus avec l'hôte. Une caractéristique des lentivirus est le transport actif du complexe de pré-intégration (PIC) dans le noyau de la cellule hôte. Le mécanisme de ce transport n'est pas connu, mais Vpr (viral protein R) pourrait être impliqué dans ce processus. Vpr reste associée au PIC jusqu'à la translocation du génome à travers la membrane nucléaire

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Peterle, Daniele. "Molecular Mechanism in the Alteration of Hemostasis." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3426350.

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Hemostasis is a finely tuned physiological process that, through the concerted action of several blood cells and proteins, maintains the integrity of the vascular system. This stepwise process begins after a vessel wall injury and includes: an initial vasospasm, a platelet plug formation (primary hemostasis), an assembly and activation of the coagulation factors that results in fibrin deposition at the site of injury (secondary hemostasis), and a final dissolution of the fibrin clot that restores the blood vessel patency (fibrinolysis) (Chapter 1). Alterations affecting one or more of these de

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Teixeira, Lúcia de Fátima Moreira. "Role and mechanism of action of human immunoregulatory iNKT cells in Leishmania infection: new approaches for vaccination?" Doctoral thesis, Faculdade de Farmácia da Universidade do Porto, 2010. http://hdl.handle.net/10216/63808.

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Teixeira, Lúcia de Fátima Moreira. "Role and mechanism of action of human immunoregulatory iNKT cells in Leishmania infection: new approaches for vaccination?" Tese, Faculdade de Farmácia da Universidade do Porto, 2010. http://hdl.handle.net/10216/63808.

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23

Rin, Ketsugi. "The suppression of p53 function due to viral infection & the molecular mechanism of p53 post-translational modifications." 京都大学 (Kyoto University), 2004. http://hdl.handle.net/2433/147928.

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24

Strange, Heather Ruth. "Mechanism of Iron Transport Employed by Neisseria Gonorrhoeae: Contribution of Ferric Binding Protein A." VCU Scholars Compass, 2007. http://scholarscompass.vcu.edu/etd_retro/80.

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FbpA is the periplasmic binding protein of the transferrin and lactoferrin-iron transport systems. FbpA is conserved among neisserial species and is required for Neisseria gonorrhoeae to sustain growth on transferrin and lactoferrin. The identification of other putative TonB-dependent outer membrane transporters suggests that gonococci may employ other uncharacterized iron uptake systems that do not require FbpA. Previous work in our lab demonstrated that gonococcal strain FA19 utilizes iron from a number of xenosiderophores of the catecholate and hydroxamate classes. In this study we cre

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Alkahlout, Amal S. "Establishment of Isoform-specific Coxsackievirus and Adenovirus Receptor Knockout Epithelial Cell Lines to Understand the Mechanism of Adenoviral Infection." Wright State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=wright1590945950982052.

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26

Makin, Laura. "Secretion from the Leishmania flagellum as a potential mechanism of virulence factor delivery." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:a5da360c-e338-49d4-828d-0479bfa4480d.

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Protozoa of the Leishmania genus are transmitted between mammalian hosts by the sandfly and cause the neglected tropical disease leishmaniasis. Upon injection into the mammalian host by the sandfly promastigote-form parasites are phagocytosed by macrophages, where they differentiate into amastigotes. Although many virulence factors are known to modulate macrophage signalling pathways to favour infection, the delivery mechanisms are largely unknown. During differentiation to amastigotes the promastigote flagellum shortens dramatically and the fate of the excess flagellar membrane is unknown. He

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Vassena, Lia. "Anti-apoptotic effects of Interleukin 7 in Human Immunodeficiency Virus Type 1 infection : mechanism and implications for immune reconstitution strategies." Thesis, Open University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.552800.

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Although HAART has introduced great improvements in the clinical outcome of HIV-1- infected individuals, the current protocols often fail in completely restoring the CD4+ T-cell lymphopenia. Therefore, innovative approaches based on the use of immune adjuvants to HAART, including cytokines like IL-2, IL-15 and IL-7, are being explored. The present thesis aims at investigating the immunomodulatory effects of IL- 7 in RIV /SIV infection, focusing on its pro-survival properties. The first part of this work describes the results of a study in vitro to evaluate the effects of IL-7 on T cells from H

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Maucourant, Christopher. "Caractérisation du découplage des fonctions des cellules natural killer au cours des infections par les virus de la dengue, du zika et du chikungunya Control of Acute Arboviral Infection by Natural Killer Cells HLA-C-restricted viral epitopes are associated with an escape mechanism from KIR2DL2+ NK cells in Lassa virus infection." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS274.

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L'histoire récente à été marquée par des épidémies récentes de dengue (Denv), Chikungunya (CHIKV) et Zika (ZIKV). Bien que ces maladies soient largement asymptomatiques, elles peuvent générer de sérieuses complications comme des formes chroniques d'arthralgies et peuvent causer des hémorragies pouvant conduire au décès (Majoritairement DENV), des microcéphalies (Maj. ZIKV) et des Syndromes de Guillain-Barré (Zikv et Chikv). Ces épidémies récentes ont poussé l'OMS à classer ces maladies comme maladies à déclaration obligatoire. A ce jour aucun traitement spécifique existe contre ces maladies re

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Hippenstiel, Stefan. "Endothel und Entzündung." Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2004. http://dx.doi.org/10.18452/13926.

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Die Aktivierung von Endothelzellen durch Bakterien und ihre Produkte trägt wesentlich zur Ausbildung klinischer Symptome in bakteriellen Infektionen bei. Die Freisetzung von Chemo- und Zytokinen führt im Konzert mit der Expression von Adhäsionsmolekülen durch das Endothel zur Rekrutierung und Aktivierung von Granulozyten. Zur Regulation der Entzündungsreaktion tragen parakrine und systemische Effekte, ausgelöst durch die Liberation von vasoaktiven Substanzen und Zytokinen durch Endothelzellen, bei. Der Zusammenbruch der endothelialen Barrierefunktion, gekennzeichnet durch den Verlust der Per

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Das, Satyajit. "Mechanism of lipid disorder in HIV infection : apolipoprotein-B kinetics, fat distribution, insulin resistance and adipocytokines in patients taking protease inhibitors or non-nucleoside reverse transcriptase inhibitors." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/1475/.

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The relationship between antiretroviral treatment of HIV infection, body fat distribution, insulin resistance (HOMA), adipocytokine and apolipoprotein-B (apoB) kinetics was investigated in 12 HIV negative controls and 55 HIV-infected patients including antiretroviral treatment-naïve patients (n=15) and patients taking two nucleoside analogues plus either a protease inhibitor (PI, n=15) or non-nucleoside reverse transcriptase inhibitor (NNRTI, n = 25). The HIV positive treatment groups had mild dyslipidaemia. The apo-B fractional clearance rate (FCR) was reduced in the HIV positive groups. Peri

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Parker-Athill, Ellisa Carla. "Maternal Immune Dysregulation in the Pathogenesis of Neurodevelopmental Disorders: Interleukin-6 as a Central Mechanism and Therapeutic Target of Flavonoids." Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4195.

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Activation of the maternal immune system and resultant maternal cytokine expression due to prenatal infection has been implicated as a significant contributor to the pathology of neuropsychiatric and neurodevelopmental disorders such as schizophrenia and Autism Spectrum Disorder (ASD). Increased maternal interleukin-6 (IL-6) expression, observed clinically and in animal models of prenatal infection, and resultant activation of key signaling pathways, has been shown to be a biological indicator of pathology, and a central component of the pathological mechanism. In animal models of prenatal i

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Branger, Judith. "Mechanisms of immune activation during infection." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2004. http://dare.uva.nl/document/88139.

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Roby, Dominique. "Reactions de defense et expression genique de plantes de melon en reponse a une infection fongique." Toulouse 3, 1987. http://www.theses.fr/1987TOU30079.

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Gollins, S. W. "Mechanisms of flavivirus neutralization and cellular infection." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355752.

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Fletcher, Patricia Susan. "Mucosal HIV-1 infection : mechanisms and microbicides." Thesis, St George's, University of London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432894.

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Wessel, Hannah Margaret. "Microbial infection and mechanisms of intestinal inflammation." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8377/.

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The intestinal immune system plays an essential role in maintaining the delicate balance between mounting protective responses against invading pathogens and sustaining tolerance towards self-antigens and the endogenous microbiota. Disturbing this balance leads to intestinal inflammation, such as is seen in inflammatory bowel disease (IBD). IBD is characterised by alterations in the mucosa-associated microbiota, such as the increase in adherent and invasive Escherichia coli (AIEC) species in Crohn’s disease (CD) patients. Concomitantly, the inflamed mucosa exhibits an elevated rate of apoptosi

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Buck, Wayne R. "Neuropathogenic mechanisms of feline immunodeficiency virus infection." Columbus, Ohio : Ohio State University, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1078414064.

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Thesis (Ph. D.)--Ohio State University, 2004.<br>Title from first page of PDF file. Document formatted into pages; contains xiv, 144 p.; also includes graphics (some col.). Includes abstract and vita. Co-advisors: Lawrence E. Mathes and Maria H. Neff, Dept. of Veterinary Biosciences. Includes bibliographical references (p. 122-144).

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BRUNELLI, CLAUDIA. "Mechanisms of translational control during Rhabdovirus infection." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2009. http://hdl.handle.net/2108/202253.

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Molti virus hanno evoluto sofisticate strategie per il controllo dell’apparato traduzionale della cellula ospite, in modo da bloccare la sintesi proteica cellulare e favorire la traduzione dei messaggeri virali. I meccanismi molecolari alla base di questo controllo sono in gran parte sconosciuti. Nel presente lavoro abbiamo studiato l’effetto dell’infezione virale su fattori cellulari che controllano l’inizio della traduzione cap-dipendente, usando come modello cellule di rene di scimmia MA104 infettate con il Virus della Stomatite Vescicolare (VSV), un rhabdovirus che è noto causare un blocco

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Khachatryan, Artashes Ruben. "Mechanisms responsible for the maintenance of high prevalence of antimicrobial drug resistant Escherichia coli in dairy calves." Online access for everyone, 2005. http://www.dissertations.wsu.edu/Dissertations/Fall2005/a%5Fkhachatryan%5F121205.pdf.

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Tu, Mu-Jung, and 杜牧融. "Study of Koi Herpesvirus Persistent Infection Mechanism." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/49153165328792509344.

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碩士<br>國立臺灣大學<br>獸醫學研究所<br>101<br>Koi herpesvirus (KHV) infection cause severe financial losses. KHV is a member of Alloherpesviridae, and newly designated species Cyprinid herpesvirus 3. The virion have an outer envelope and an icosahedral capsid contains a single, linear, double-stranded DNA of 295 kbp. Common carp (Cyprinus carpio carpio) and Koi carp(Cyprinus carpio koi) are the only species known to be affected by KHV. The survivors will become carrier fishes, but persistent infection mechanism of KHV is not clear. One of the unique features of Herpesviridae is latency which had been confi

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"Construction of a dual infection mechanism for HIV." UNIVERSITY OF MARYLAND, BALTIMORE COUNTY, 2009. http://pqdtopen.proquest.com/#viewpdf?dispub=1465379.

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Tsai, Fu-Ming, and 蔡福明. "The mechanism of dengue virus infection of human monocyte." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/72974150643731171621.

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碩士<br>國防醫學院<br>微生物及免疫學研究所<br>88<br>Dengue virus is an arthropod-borne human pathogen that represents a serious public health threat. The clinical manifestations of dengue virus infection range in severity from a simple febrile illness to a hemorrhagic fever and a potentially fatal hemorrhagic shock syndrome. Dengue virus gains entry to some cell types by an immune adherence bridging phenomenon which is dependent on the presence of nonneutralizing antibodies. However, this mechanism cannot explain primary infections in patients without antibody to dengue virus and the ability of dengue virus to

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Chio, Chi Chong, and 趙梓聰. "The molecular mechanism of Curcumin in enterovirus 71 infection." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/8y54sm.

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Kao, Jo-Chi, and 高若綺. "Molecular Mechanism of Antiparasitic Niclosamide against Dengue Virus Infection." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/3wwg79.

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Chen, Zih-Yan, and 陳姿雁. "A mechanism of curcumin on anti-influenza A virus infection." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/59996194091997919720.

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碩士<br>國立中興大學<br>獸醫學系暨研究所<br>98<br>Curcumin (a natural compound from curry) has been shown to exert anti-inflammatory, antioxidant, and anticarcinogenesis properties, acting through modulation of signal transduction pathways including NF-kappaB, required for efficient replication of influenza virus. Extending from our previous observation that treatment of curcumin efficiently blocked influenza replication and haemagglutination (HA) activity, the goal of present study focuses on investigation of the mechanism of anti-influenza activity mediated by curcumin. The result indicated that curcumin tr

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Hamilton, Phineas T. "Defensive symbiosis in Drosophila: from multiple infections to mechanism of defense." Thesis, 2015. http://hdl.handle.net/1828/6962.

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Multiple infections within the same host are now understood to be common and important determinants of the outcomes of disease processes. Multiple infections are particularly important in insects, which are often infected by vertically transmitted symbionts that are passed from the mother to her offspring. In many cases, these symbionts have evolved to confer high levels of protection against co-infecting parasites, pathogens, or other natural enemies. Despite widespread examples of symbiont-mediated defense, there are key outstanding questions in the ecology and evolution of defensive symbios

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Su, Pao-Cheng, and 蘇保誠. "The mechanism of the Salmonella invasion related with CSFV co-infection." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/41546020282208501872.

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碩士<br>國立中興大學<br>獸醫病理學研究所<br>93<br>The aim of this study is to utilize immunohistochemistry (IHC) and surgically constructed intestinal loops to investigate the invasion mechanisms of the Salmonella enterica serovars Choleraesuis and Salmonella enterica serovars Typhimurium in pigs. Inoculation of Salmonella Typhimurium resulted in acute necrotic ileitis with accumulation of large amount of neutrophils infiltration in the lamina propria, whereas inoculation of Salmonella Cholearesuis that induced mononuclear cells infiltration. The results of IHC also indicate that greater numbers of Salmonella

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Huang, Yng-Huey, and 黃盈慧. "Study on the Mechanism of Hemorrhage Induced by Dengue Virus Infection." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/54213571582867420577.

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博士<br>國立成功大學<br>基礎醫學研究所<br>89<br>Dengue hemorrhagic fever (DHF) is an acute, potentially life-threatening, capillary leakage syndrome caused by the dengue virus (DV), a group of four antigenically related flavivirus designated serotypes 1 through 4. In contrast, classical dengue fever (DF) is an acute self-limited febrile illness. The clinical symptoms of DHF/DSS include plasma leakage documented by hemoconcentration, thrombocytopenia, and hypovolemic shock. The mechanism of DHF/DSS is still not fully understood. There are several evidences suggesting that hemorrhage in DHF is related to a com

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Liao, Wen-yu, and 廖汶瑜. "Molecular Mechanism of Salmonella-Enhanced Inflammasome Activation during Dengue Virus Infection." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/23649953505361896838.

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碩士<br>國立陽明大學<br>臨床醫學研究所<br>101<br>Abstract Dengue virus (DV) infection is one of the most important arthropod-borne disease in the tropical and subtropical areas, and is estimated to cause 50 million infections annually. Infection with DV may be asymptomatic in the majority of cases, but DV infection result in a wide spectrum of clinical symptoms, ranging from dengue fever (DF) to the most severe disease, dengue hemorrhagic fever (DHF) /dengue shock syndrome (DSS). In most cases, concurrent infection with two dengue virus strains from two different serotypes in a patient correlates with se

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Chen, Yue Qin, and 陳月琴. "The mechanism(s) of epstein-barr virus infection in nasopharyngeal carcinoma." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/87403416360588985663.

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