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Journal articles on the topic 'Mechanisms of suicidal behavior'

Author: Grafiati

Published: 28 May 2022

Last updated: 30 July 2025

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1

Dawes, Michael A., Charles W. Mathias, Dawn M. Richard, Nathalie Hill-Kapturczak, and Donald M. Dougherty. "Adolescent Suicidal Behavior and Substance Use: Developmental Mechanisms." Substance Abuse: Research and Treatment 2 (January 2008): SART.S1044. http://dx.doi.org/10.4137/sart.s1044.

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Adolescent suicidal behaviors and substance use are disturbingly common. Research suggests overlap of some of the etiological mechanisms for both adolescent suicidal behavior and substance use, yet clear understanding of the complex relations between these behaviors and their causal underpinnings is lacking. A growing body of evidence and a diathesis model (Mann et al. 1999; Mann, 2003) highlight the importance of impulse control as a proximal risk factor for adolescent suicidal and substance use behaviors. This literature review extends current theory on the relationships between adolescent s

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González-Castro, Thelma Beatriz, Alma Delia Genis-Mendoza, Dulce Ivannia León-Escalante, et al. "Possible Association of Cholesterol as a Biomarker in Suicide Behavior." Biomedicines 9, no. 11 (2021): 1559. http://dx.doi.org/10.3390/biomedicines9111559.

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Suicides and suicidal behavior are major causes of mortality and morbidity in public health and are a global problem. Various authors have proposed changes in lipid metabolism (total cholesterol decrease) as a possible biological marker for suicidal behavior. The objective of this study was to review the studies that have demonstrated a relationship between serum cholesterol levels and suicidal behavior and to describe the possible pathophysiological mechanisms that associate changes in cholesterol concentration and suicidal behavior. Relevant literature related to serum cholesterol levels and

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Khudina, Yu S., N. V. Tkachenko, and V. G. Zaika. "The relationship between suicidal behavior and personality and affective-behavioral characteristics in patients with organic personality disorder." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 5 (April 28, 2025): 630–39. https://doi.org/10.33920/med-01-2505-08.

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Studies devoted to the topic of suicidal behavior, including in patients with organic personality disorder, are represented mainly by completed suicides. The description of incomplete suicides in this group of subjects is extremely superficial. Given the diversity of mechanisms and factors predisposing suicidal behavior, we decided to analyze this problem and assess the level of aggression, emotional excitability, and impulsivity. A comparative single-step observational study of 94 patients with organic personality disorder was conducted. The participants were divided into subgroups: patients

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van Praag, H. M. "Serotonergic mechanisms and suicidal behavior." Psychiatry and Psychobiology 3, no. 5 (1988): 335–46. http://dx.doi.org/10.1017/s0767399x00002479.

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SummaryDisturbances in central serotonin (5-hydroxytryptamine, 5-HT) were first described in depression. They were inferred to exist based on the finding of lowered baseline and post-probenecid concentrations of 5-HIAA in CSF. Initially, depressed patients with and without deimonstrable disturbances in central 5-H1 seemed psychopathologically indistinguishable. Interpreting the available data, at that time, we introduced in 1971 the concept of biochemical heterogeneity of depression. Some forms, we postulated, are linked to disturbances in 5-HT functions, others are not or, to a much lesser ex

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Yamamoto, Mana, Mai Sakai, Zhiqian Yu, Miharu Nakanishi, and Hatsumi Yoshii. "Glial Markers of Suicidal Behavior in the Human Brain—A Systematic Review of Postmortem Studies." International Journal of Molecular Sciences 25, no. 11 (2024): 5750. http://dx.doi.org/10.3390/ijms25115750.

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Suicide is a major public health priority, and its molecular mechanisms appear to be related to glial abnormalities and specific transcriptional changes. This study aimed to identify and synthesize evidence of the relationship between glial dysfunction and suicidal behavior to understand the neurobiology of suicide. As of 26 January 2024, 46 articles that met the inclusion criteria were identified by searching PubMed and ISI Web of Science. Most postmortem studies, including 30 brain regions, have determined no density or number of total Nissl-glial cell changes in suicidal patients with major

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Tomé-Fernández, Mario, Marina Berbegal-Bernabeu, Miriam Sánchez-Sansegundo, et al. "Neurocognitive Suicide and Homicide Markers in Patients with Schizophrenia Spectrum Disorders: A Systematic Review." Behavioral Sciences 13, no. 6 (2023): 446. http://dx.doi.org/10.3390/bs13060446.

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Suicide and homicide are considered important problems in public health. This study aims to identify the cognitive performance of suicidal and homicidal behaviors in people with schizophrenia spectrum disorders, as well as examining whether there are shared neuropsychological mechanisms. A systematic review of the recent literature was carried out from September 2012 to June 2022 using the Medline (via PubMed), Scopus, Embase, and Cochrane databases. Among the 870 studies initially identified, 23 were finally selected (15 related to suicidal behaviors and 8 to homicidal behaviors). The results

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7

Coleman, Daniel, and John T. Casey. "Therapeutic Mechanisms of Suicidal Ideation." Crisis 28, no. 4 (2007): 198–203. http://dx.doi.org/10.1027/0227-5910.28.4.198.

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The treatment processes associated with reduced suicidal ideation have received little research attention. This study evaluates the influence on suicidal ideation of theory-based intrapsychic processes: maladaptive cognition and defensive style. Thirty-three community mental health patients completed questionnaires at two time points. Decreases in automatic thoughts were a strong correlate of decreased suicidal ideation, and decreases in immature defenses were a moderate strength correlate. These relationships remained significant even when controlling for initial level of depression. The theo

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Rosario-Hernández, Ernesto, Lillian V. Rovira-Millán, Stephanie Vega-Vélez, et al. "Effects of Workplace Bullying on Suicide Behavior Using the Integrated Motivational-Volitional Model of Suicide Behavior." Revista Interamericana de Psicología Ocupacional 40, no. 1 (2025): 60–82. https://doi.org/10.71332/1nq47c97.

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This study explored the relationship between workplace bullying (WB) and suicidal behavior among Puerto Rican employees using the Integrated Motivational-Volitional (IMV) model. WB and suicidal behavior are significant public health concerns, but limited research has examined the connection between WB and suicidal attempts, particularly in Puerto Rico. The study involved 931 employees from various organizations, utilizing partial least squares structural equation modeling (PLS-SEM) to analyze the data. The results revealed that WB is significantly associated with suicidal ideation, suicidal at

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Collados-Ros, Aurelia, Carmen Torres-Sánchez, María Dolores Pérez-Cárceles, Aurelio Luna, and Isabel Legaz. "Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological Findings." Toxics 10, no. 6 (2022): 319. http://dx.doi.org/10.3390/toxics10060319.

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Suicide affects all sociodemographic levels, age groups, and populations worldwide. The factors that can increase the risk of suicidal tendencies are widely studied. The aim of this study was to analyze the types and combinations of toxics found in fatal suicide victims with different suicide mechanisms. A total of 355 autopsies were retrospectively studied, and 26 toxics were determined and related to mechanisms of suicide. Hanging (55%), drug overdose (22.7%), and jumping from a height (17.8%) were most represented suicide mechanisms with positive toxicology. Hanging was the most represented

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Aaltonen, K., T. Rosenström, I. Baryshnikov, et al. "A Mediation Analysis of Childhood Maltreatment and Suicidal Behavior among Patients with Depressive or Bipolar Disorders." European Psychiatry 41, S1 (2017): S85. http://dx.doi.org/10.1016/j.eurpsy.2017.01.269.

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IntroductionSubstantial evidence supports association between childhood maltreatment and suicidal behaviour, however, a limited number of studies have examined psychological mechanisms mediating the relationship among patients with mood disorders.ObjectiveTo investigate directly the potential intermediating mechanisms between childhood maltreatment and suicidal behaviour among patients with mood disorders.AimsWe examine by formal mediation analyses, if:– the effect of childhood maltreatment on suicidal behaviour is mediated through borderline personality disorder traits;– the mediation effect

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Nguyen, Thi Mai Loan, Fabrice Jollant, Laurent Tritschler, Romain Colle, Emmanuelle Corruble, and Alain M. Gardier. "Pharmacological Mechanism of Ketamine in Suicidal Behavior Based on Animal Models of Aggressiveness and Impulsivity: A Narrative Review." Pharmaceuticals 16, no. 4 (2023): 634. http://dx.doi.org/10.3390/ph16040634.

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Around 700,000 people die from suicide each year in the world. Approximately 90% of suicides have a history of mental illness, and more than two-thirds occur during a major depressive episode. Specific therapeutic options to manage the suicidal crisis are limited and measures to prevent acting out also remain limited. Drugs shown to reduce the risk of suicide (antidepressants, lithium, or clozapine) necessitate a long delay of onset. To date, no treatment is indicated for the treatment of suicidality. Ketamine, a glutamate NMDA receptor antagonist, is a fast-acting antidepressant with signific

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Fekete, J. D., and S. Fekete. "Content analysis of suicidal notes - the verbal behaviour." European Psychiatry 67, S1 (2024): S781. http://dx.doi.org/10.1192/j.eurpsy.2024.1626.

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Introduction There have been numerous studies on attempted and completed suicides in an attempt to understand better the phenomenon - the tragedy- of self-destructive behaviour through the analysis of the suicidal notes – their last personal documents, that many individuals write before carrying out suicide. Understanding and interpretation of these analyses could happen on several theoretical frameworks and background Research has systematically demonstrated what most clinicians assume, namely that individuals sharing significant patterns of nonverbal behavior express these tendencies in thei

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Saifullah, Kainat, Warisha Zaffar, Halima Sadia Qureshi, Rehmat Ullah, and Laraib. "<b>Social Isolation, Perceived Stigma, Avoidance Behaviour And Sucidial Ideation Among Individuals With Substance Use Disorder: A Cross Sectional Study</b>." Journal of Political Stability Archive 3, no. 3 (2025): 317–31. https://doi.org/10.63468/jpsa.3.3.23.

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Substance Use Disorder (SUD) is linked to several psychosocial issues, including social isolation, perceived stigma, avoidance behavior, and suicidal ideation. Individuals with SUD often experience social rejection and internalize negative societal attitudes, leading to emotional distress and withdrawal from support systems. To cope, many engage in avoidance behaviors, which further isolate them and increase the risk of suicidal thoughts. These interconnected factors create a cycle of psychological pain that worsens over time. Despite their significance, these variables are not well studied to

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Ivanov, Roman, Larisa Ivanova, and Tatyana Maltseva. "The problem of suicidal behavior in adolescence." Applied psychology and pedagogy 6, no. 4 (2021): 200–208. http://dx.doi.org/10.12737/2500-0543-2021-6-4-200-208.

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The article examines the problems of suicidal behavior in adolescents, as well as ways to prevent and counteract this destructive behavior. This is due today to the great urgency of this social problem, both for the Russian and for the world community. In the study, the tasks were set to study the characteristics of suicidal behavior in adolescents; the study of the social significance of adolescent suicide in the public consciousness in order to determine ways to solve the problem of suicidal behavior in adolescents to reduce suicidal moods among young people. Among the causes of suicidal beh

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Mehmood, Muzna, Noor-ul-ain Awan, Tooba Fiaz, and Syeda Aliya Raza. "Prevalence of non-suicidal self-injury in medical students of Rawalpindi; its socio-demographics, methods, and functions." Journal of the Pakistan Medical Association 73, no. 12 (2023): 2370–74. http://dx.doi.org/10.47391/jpma.7544.

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Objective: To investigate the prevalence of non-suicidal self-injury among Pakistani medical students, its association with demographic variables, and the distribution of its methods and functions. Method: The cross-sectional study was conducted in from April 2021 to March 2022 at Rawalpindi Medical University, Rawalpindi, Pakistan, and comprised medical students regardless of gender and year of study. Data was collected using the inventory of statements about self-harm scale to assess their socio-demographics, non-suicidal self-injury behaviors and functions. Data was analyzed using SPSS 28.

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Maruta, Nataliya, Iryna Mudrenko, Galyna Kalenska, and Mykhailo Denysenko. "Suicidal behavior in patients with dementia." Ukrains'kyi Visnyk Psykhonevrolohii, Volume 28, issue 4 (105) (December 28, 2020): 4–12. http://dx.doi.org/10.36927/2079-0325-v28-is4-2020-1.

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203 patients were examined, including 75 with dementia at Alzheimer’s disease (AD), 73 with vascular dementia (VD) and 60 patients with mixed dementia (MD). Patients were divided into main and control group by the factor of presence/absence of signs of suicidal behavior (intentions, attempts, thoughts, anti-vital mood, statements). Among patients with AD, 36 patients were the main group, 39 were the control group; at VD 39 patients were main group, 34 were control group; in mixed dementia, 30 patients were included in the main group, 30 patients were in the control group. It has been found tha

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Perlman, Greg, Brady Nelson, Greg Hajcak Proudfit, Daniel Klein, and Roman Kotov. "Neural mechanisms of non-suicidal self-injury and suicidal behavior in adolescent girls." Comprehensive Psychiatry 55, no. 8 (2014): e56. http://dx.doi.org/10.1016/j.comppsych.2014.08.034.

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Serafini, G., M. Pompili, P. Girardi, and M. Amore. "The impact of neuroinflammation and inflammatory cytokines in depression and suicidal behavior." European Psychiatry 33, S1 (2016): S160. http://dx.doi.org/10.1016/j.eurpsy.2016.01.311.

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IntroductionIt has been suggested that neuroinflammation and inflammatory mediators may play a crucial role in the pathophysiology of both major depression and suicidal behavior. Immunological differences have been reported between both subjects with major affective disorders and suicidal behavior.ObjectivesThe main objective of this review was to deeply investigate the nature of the association between inflammatory cytokines in depression and suicidal behavior. Aims: The study aimed to conduct a systematic review of the current literature to investigate the association between inflammatory cy

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Sagalakova, Olga A., Dmitry V. Truevtsev, and Olga V. Zhirnova. "The Psychological Role of Dissociation and Repetitive Negative Thinking in the Development of Suicidal Behavior in Posttraumatic Stress Disorder." Neurology Bulletin LVII, no. 2 (2025): 180–93. https://doi.org/10.17816/nb642098.

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Cognitive and metacognitive processes, along with dissociative symptoms, play a significant role in the development of suicidal behavior in the context of traumatic experiences and posttraumatic stress disorder. This article reviews theoretical models that conceptualize the transition from suicidal ideation to actions, emphasizing the mechanisms and mediating variables underlying this progression. The discussed models include the interpersonal theory of suicide, the three-step theory, the integrated motivational–volitional model, the perfectionism-based model of suicide risk, the fluid vulnera

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Ruiz-Robledillo, Nicolás, Rosario Ferrer-Cascales, Natalia Albaladejo-Blázquez, and Miriam Sánchez-SanSegundo. "Family and School Contexts as Predictors of Suicidal Behavior among Adolescents: The Role of Depression and Anxiety." Journal of Clinical Medicine 8, no. 12 (2019): 2066. http://dx.doi.org/10.3390/jcm8122066.

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Suicide is the highest external cause of death in the majority of developed countries. In adolescents, the prevalence of suicide has increased significantly in recent years, becoming a serious public health concern. The main aim of the present study is to characterize suicidal behavior, and to evaluate the relationship between family and school contexts and suicidal behavior through the possible mediating effects of depression and anxiety. The design of the study is cross-sectional. The sample was composed of 1386 Spanish adolescents from 14 high-schools. Suicidal behavior, anxiety, depression

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Febrita, Jeantriani, and Eka Margianti Sagimin. "Self-Destructive Behavior Analysis of Hannah Baker in The Thirteen Reasons Why Novel." Jurnal DinamikA 1, no. 2 (2020): 16–32. http://dx.doi.org/10.18326/dinamika.v1i2.16-32.

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This study investigates Self-Destructive Behavior of Hannah Baker in Thirteen Reasons Why novel, conducted in qualitative approach analysis of self-destructive behavior of the main character and what reasons or the causes of it through the narratives in the Thirteen Reasons Why novel. The goal of the study is to analyze how self-destructive behavior impacted the main character, Hannah Baker which is described using the theory of Self-Destructive Behavior and Defense Mechanisms by Sigmund Freud (1966). The result of this study shows that Hannah Baker developed the self-destructive behavior as a

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Recklitis, Christopher J., Gil G. Noam, and Sophie R. Borst. "Adolescent Suicide and Defensive Style." Suicide and Life-Threatening Behavior 22, no. 3 (1992): 374–87. http://dx.doi.org/10.1111/j.1943-278x.1992.tb00742.x.

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ABSTRACT: This empirical study investigated the relation between ego defense mechanisms, diagnoses, and suicidality among 200 adolescent psychiatric patients ages 12 to 16 years. Based on a structured diagnostic interview, adolescents were divided into three groups: suicide attempters, suicidal ideators, and nonsuicidal patients. Using the Defense Mechanisms Inventory (DMI), suicidal adolescents scored higher on the defense of turning‐against‐self and lower on reversal, as compared to nonsuicidal adolescents. Although suicide was significantly more common among adolescents with an affective di

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Bardina, E. Y., U. S. Efremova, A. M. Baikova3, et al. "Genetic Associations of the Polymorphic Variant of the DRD2 (rs1800497) Gene with Forms of Suicidal Behavior in Patients with Alcohol Dependence." Personalized Psychiatry and Neurology 4, no. 1 (2024): 26–31. http://dx.doi.org/10.52667/10.52667/2712-9179-2024-4-1-26-31.

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Suicide is a serious public health problem. A deeper understanding of the underlying mechanisms and processes that lead to suicidal behavior is crucial for the development of effective preventive strategies. The study and identification of biomarkers will help in understanding the underlying processes or changes associated with suicide, however, studies linking biomarkers to suicide are limited and fragmented. Objective- To study the genetic associations of the polymorphic variant of the DRD2 gene (rs1800497) with forms of suicidal behavior in patients with alcohol dependence. Materials and me

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Knizhnikova, Svetlana V. "Parents’ Perceptions of Suicide and Requests for Increased Awareness in Prevention of Children’s Suicidal Behavior." Integration of Education 28, no. 3 (2024): 400–420. http://dx.doi.org/10.15507/1991-9468.116.028.202403.400-420.

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Introduction. The issue of suicidal behavior among minors highlights the need to explore preventive measures within the family. Optimizing family-based suicide prevention for children necessitates the assessment of parental awareness regarding the phenomenon of suicidal behavior and the potential strategies for prevention. This serves as the primary objective of the study. Materials and Methods. A survey was conducted embracing 3,866 parents and containing 85 questions testing parents’ perceptions on suicide determinants, behavioral risk signals, understanding of response methods to avert suic

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Darin, E. V. "Non-suicidal self-harming behavior of adolescents." Medical Herald of the South of Russia 10, no. 4 (2019): 6–14. http://dx.doi.org/10.21886/2219-8075-2019-10-4-6-14.

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Th e article discusses non-suicidal self-harming behavior (NSPP) in adolescents, which is currently a widespread problem both in the Russian Federation and around the world. Th e main types and forms of NSPP, the causes and mechanisms of occurrence, the diff erence from other forms of self-destructive behavior are considered.

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Vestergaard, Camilla Beck, and Carsten René Jørgensen. "Selvskadende adfærd på sociale medier." Psyke & Logos 37, no. 2 (2017): 60–77. http://dx.doi.org/10.7146/pl.v37i2.25683.

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Traditionally non-suicidal self-injury has been seen as shameful behavior and those suffering from it have concealed it from their surrounding environment. There is a tendency that is growing amongst adolescents with non-suicidal self-injury behavior, in particular adolescent girls, who are now sharing graphic pictures of their non-suicidal self-injurieson social media platforms such as Instagram. This article investigates the psychological mechanisms, which lie behind this phenomenon. This is done within a clinical group of adolescents with non-suicidal self-injury behavior. It is suggested t

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Sher, Leo. "Low testosterone levels may be associated with suicidal behavior in older men while high testosterone levels may be related to suicidal behavior in adolescents and young adults: a hypothesis." International Journal of Adolescent Medicine and Health 25, no. 3 (2013): 263–68. http://dx.doi.org/10.1515/ijamh-2013-0060.

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Abstract Several lines of evidence suggest that there is an association between testosterone and suicidal behavior. A link between testosterone and the neurobiology of suicidal behavior may be related to: a) a direct effect of testosterone on suicidality via certain brain mechanisms; and/or b) a testosterone influence on aggression and, consequently, suicidality; and/or c) a testosterone effect on mood and, consequently, suicidality; and/or d) a testosterone effect on cognition and, consequently, suicidality. At least one study has demonstrated a relation between high levels of testosterone an

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Alsaleh, Amer. "The Impact of Community Structural Instability on Bedoon and Suicidal Behavior in Kuwait." African and Asian Studies 13, no. 3 (2014): 272–90. http://dx.doi.org/10.1163/15692108-12341299.

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The current study examines the impact of community structural instability on the suicidal behaviors of the indigenous community of the Bedoon in Kuwait. I hypothesize that the Bedoon’s lack of documentation and limited opportunities in Kuwait, combined with community structural instability, increase suicide ideation and attempts. The contextual influence of community structural instability should be mediated by weak attachments to social norms and values (anomie) and by contact with suicidal others (attempt and ideation). The data, coming from a survey of 2,583 Bedoon adolescents between 14 an

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Tondo, Leonardo, and Ross J. Baldessarini. "History of Suicide Prevention with Lithium Treatment." Pharmaceuticals 18, no. 2 (2025): 258. https://doi.org/10.3390/ph18020258.

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Suicidal behavior is prevalent among individuals with psychiatric illnesses, especially mood, substance abuse, and psychotic disorders. Over the past several decades, lithium treatment in patients with mood disorders has been increasingly used to lower the risk of suicidal behavior. This overview considers that lithium treatment has the most abundant evidence of reducing suicidal behavior. It also examines the hypothesis that higher natural lithium levels in drinking water correlate with reduced suicide rates. We report findings from trials comparing lithium treatment with its absence, placebo

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Zinchuk, Mikhail S., Tatiana A. Druzhkova, Sofya B. Popova, Marina Y. Zhanina, Alla B. Guekht, and Natalia V. Gulyaeva. "Early Adverse Family Experiences and Elevated Adrenocorticotropic Hormone Predict Non-Suicidal Self-Injury in Females with Non-Psychotic Mental Disorders and Suicidal Ideation." Biomedicines 11, no. 12 (2023): 3181. http://dx.doi.org/10.3390/biomedicines11123181.

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Nonsuicidal self-injurious behavior (NSSI), prevalent in patients with non-psychotic mental disorders (NPMD), is associated with numerous adverse outcomes. Despite active research into the clinical and psychological aspects of NSSI, the underlying biological mechanisms remain obscure. Early adverse experiences are believed to induce long-lasting changes in neuroendocrine mechanisms of stress control playing a key role in NSSI development. The aim of the study was to evaluate parameters potentially predicting development of NSSI in female patients with NPMD and suicidal ideation. Eighty female

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Grigoriou, M., R. Reniers, P. Mallikarjun, and R. Upthegrove. "Reduced prefrontal activity and suicidal behaviour in early schizophrenia." European Psychiatry 64, S1 (2021): S543. http://dx.doi.org/10.1192/j.eurpsy.2021.1449.

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IntroductionApproximately, 15- 26% of patients with first-episode psychosis, including schizophrenia, are likely to have attempted suicide by their first treatment contact. Studies of suicidal behavior outside of schizophrenia have indicated grey matter volume loss in the prefrontal and orbitofrontal cortex, and aberrant brain activity in relation to emotional recognition and dysfunction.ObjectivesThis study aimed to investigate the functional neural correlates of suicidal behavior in early schizophrenia.MethodsfMRI faces task was conducted (fearful face versus neutral face) in 8 participants

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Dobry, Yuriy, and Leo Sher. "The underexamined association between posttraumatic stress disorder, medical illness and suicidal behavior." International Journal of Adolescent Medicine and Health 25, no. 3 (2013): 279–82. http://dx.doi.org/10.1515/ijamh-2013-0063.

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Abstract Posttraumatic stress disorder (PTSD) is concerning not only because of the severity and chronicity of its symptoms – including distressing nightmares, flashbacks, anxiety attacks and maladaptive patterns of avoidant and nearly paranoid behavior – but also because of the wide spectrum of clinical and social impairments it is tightly associated with. The most striking example of clinical morbidity associated with PTSD is the well-known increase in the risk of suicidal behavior. Given that PTSD and medical illnesses increase the likelihood of suicide separately and independently, it is r

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Castillo-Zúñiga, Iván, Francisco-Javier Luna-Rosas, and Jaime-Iván López-Veyna. "Detection of traits in students with suicidal tendencies on Internet applying Web Mining." Comunicar 30, no. 71 (2022): 105–17. http://dx.doi.org/10.3916/c71-2022-08.

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This article presents an Internet data analysis model based on Web Mining with the aim to find knowledge about large amounts of data in cyberspace. To test the proposed method, suicide web pages were analyzed as a study case to identify and detect traits in students with suicidal tendencies. The procedure considers a Web Scraper to locate and download information from the Internet, as well as Natural Language Processing techniques to retrieve the words. To explore the information, a dataset based on Dynamic Tables and Semantic Ontologies was constructed, specifying the predictive variables in

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Tussupova, A. B., R. K. Tatayeva, Zh P. Sembaeva, S. I. Chukhatina, O. Yu Fedorenko, and M. M. Baibulova. "Serotonergic and dopaminergic system genes and their polymorphisms associated with suicidal behavior." BULLETIN OF THE L.N. GUMILYOV EURASIAN NATIONAL UNIVERSITY. BIOSCIENCE SERIES 151, no. 2 (2025): 41–61. https://doi.org/10.32523/2616-7034-2025-151-2-41-61.

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Suicidal behavior is a complex, multifactorial phenomenon caused by the interaction of biological, psychological, social, and environmental factors. One of the key areas in the study of the biological basis of suicidal behavior is the study of genetic predisposition, which is confirmed by family, twin, and molecular genetic studies. A special role in the regulation of affective states and suicidal behavior is played by genes of the serotonergic (TPH1, TPH2, 5HTR2A, 5-HT1A, SLC6A4, 5-HT2C, MAOA) and dopaminergic (ANKK1, DRD2, COMT) systems. Serotonin is the main neurotransmitter involved in the

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Ljung, T., P. Lichtenstein, S. Sandin, et al. "Parental schizophrenia and increased offspring suicide risk: exploring the causal hypothesis using cousin comparisons." Psychological Medicine 43, no. 3 (2012): 581–90. http://dx.doi.org/10.1017/s0033291712001365.

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BackgroundLittle is known about suicide risk among offspring of parents hospitalized for schizophrenia and the mechanisms behind this association.MethodWe applied a nested case–control design based on linkage of Swedish population-based registers. Among 12- to 30-year-old offspring, we identified 68 318 offspring with suicidal behavior (attempted and completed suicide) and their parents. Five healthy control–parent pairs were matched to each suicidal case–parent pair and conditional logistic regression used to obtain odds ratios (ORs). Further, to disentangle familial confounding from causal e

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Neiva Porto Silva, Camila, Joelson Germano Crispim, Celina Cavalcante Muniz, Arthur Vinicius da Silva Cabral, Camilla De Andrade Tenorio Cavalcanti, and Michelle Melgarejo da Rosa. "GENETIC FACTORS INVOLVED IN SUICIDAL BEHAVIOR." International Journal of Health Sciences 5, no. 1 (2025): 89–96. https://doi.org/10.31692/2764-3433.v5i1.305.

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Suicidal behavior (SB) is a global public health problem, with suicide being one of the main challenges commonly associated with mental disorders and neurobiological and genetic alterations. SB has been described as a complex gene-environment interaction involving emotional regulation, cognition, and stress responses, with the hypothalamic-pituitary-adrenal axis being fundamental in stress regulation through the release of hormones such as cortisol. The objective was to list the main associations between genotype and SB. For this, open-access articles in English published between 2021 and 2024

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Hagan, Christopher R., Megan L. Rogers, Amy M. Brausch, Jennifer J. Muehlenkamp, and Thomas E. Joiner. "Interoceptive deficits, non-suicidal self-injury, and suicide risk: a multi-sample study of indirect effects." Psychological Medicine 49, no. 16 (2019): 2789–800. http://dx.doi.org/10.1017/s0033291718003872.

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AbstractBackgroundInteroceptive deficits (ID) have been associated with non-suicidal self-injury (NSSI) and suicidal behavior in multiple studies. Many of these studies are limited in scope, and have not fully examined possible mechanisms explaining how ID affect suicidal behavior.MethodsThis study assesses how self-reported ID relate to suicide ideation and attempts in six distinct and geographically diverse samples of adults (n = 2706) and one sample of adolescents (n = 436). Participants responded to a variety of self-report questionnaires and interviews.ResultsContrary to our hypothesis, s

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Tatayeva, Roza, Aruzhan Tussupova, Sholpan Koygeldinova, Sandugash Serkali, Ainash Suleimenova, and Bauyrzhan Askar. "The Level of Serotonin and the Parameters of Lipid Metabolism Are Dependent on the Mental Status of Patients with Suicide Attempts." Psychiatry International 5, no. 4 (2024): 773–92. http://dx.doi.org/10.3390/psychiatryint5040053.

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Suicidal behavior is an important public health problem often associated with psychological and biological factors. Understanding the role of biochemical markers, such as cholesterol and serotonin levels, may provide insight into the mechanisms underlying suicidal tendencies. This study aimed to investigate the relationship between lipid profile parameters, serotonin levels, and psychological status in individuals who had attempted suicide. Patients with suicidal attempts underwent a psychiatric evaluation and blood samples were taken to measure serotonin levels, total cholesterol, and lipid m

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Courtet, P. "Clinical Use of Biomarkers in Suicidal Behaviors." European Psychiatry 41, S1 (2017): S41. http://dx.doi.org/10.1016/j.eurpsy.2017.01.184.

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The epidemiology, risk factors, and biological basis of suicidal behaviors have been the object of an ever–increasing research in the last three decades. During this period, researchers all over the world have identified potential biomarkers of risk and developed several theories about the mechanisms leading to suicidal behavior. However, the lack of common terminology, instruments, and cooperation has been a major deterrent. Today, the community has established the bases for this collaboration and evidence coming from neuroscientific studies can already be applied to the field of suicidology.

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Kralik, Kathleen M., and Walter J. Danforth. "Identification of Coping Ideation and Strategies Preventing Suicidality in a College‐Age Sample." Suicide and Life-Threatening Behavior 22, no. 2 (1992): 167–86. http://dx.doi.org/10.1111/j.1943-278x.1992.tb00227.x.

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ABSTRACT: This study attempts to identify coping mechanisms relevant to the prevention of progressive lethality in suicidal behavior among youth. College students (N = 296) aged 18 to 24, self‐identified as having no past suicidal ideation, mild ideation, severe ideation, or having attempted suicide, completed the Reasons for Living Inventory (Linehan, Goodstein, Nielson, & Chiles, 1983), a similarly derived instrument for age‐specific coping cognitions, and a scale of coping strategies for diminishing suicidality. Discriminant functions analyses of the mean factor scores for each scale we

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Popova, Nina K., Anton S. Tsybko, and Vladimir S. Naumenko. "The Implication of 5-HT Receptor Family Members in Aggression, Depression and Suicide: Similarity and Difference." International Journal of Molecular Sciences 23, no. 15 (2022): 8814. http://dx.doi.org/10.3390/ijms23158814.

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Being different multifactorial forms of psychopathology, aggression, depression and suicidal behavior, which is considered to be violent aggression directed against the self, have principal neurobiological links: preclinical and clinical evidence associates depression, aggression and suicidal behavior with dysregulation in central serotonergic (5-HT) neurotransmission. The implication of different types of 5-HT receptors in the genetic and epigenetic mechanisms of aggression, depression and suicidality has been well recognized. In this review, we consider and compare the orchestra of 5-HT rece

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Bannikov, G. S., N. Y. Fedunina, T. S. Pavlova, O. V. Vikhristyuk, A. V. Letova, and M. D. Bazhenova. "Mechanisms of self-harm behavior in non-clinical adolescent population: the results of monitoring in Moscow schools." Консультативная психология и психотерапия 24, no. 3 (2016): 42–68. http://dx.doi.org/10.17759/cpp.2016240304.

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The behavior of self-harm is prevalent among adolescents. Most research on the topic has focused either on qualitative investigation of hospitalized teens or on quantitative research of non-clinical population. There combination of these approaches is considered very promising, yet it is extremely rare. The present article investigates the behavior of self-harm without suicidal intention in non-clinical population. The participants were 604 students of Moscow schools (7—11 grades). 22% participants reported at least 1 act of deliberate self-harm in the lifetime period (54% — single episode, 46

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Li, Yinuo. "A Study of the Neurobiological Mechanisms of Non-suicidal Self-injurious Behaviour." Communications in Humanities Research 46, no. 1 (2024): 142–45. http://dx.doi.org/10.54254/2753-7064/46/20242286.

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Non-suicidal self-injury (NSSI) often occurs in adolescence and early adulthood, accompanied by an increase in the incidence and development of related diseases, making it a significant risk factor for suicide. NSSI behavior among adolescents has become a serious public health issue, threatening their physical and mental development. This article explores the identification methods, biological causes, and emotional causes of NSSI behavior and provides current applicable treatment interventions. By elaborating on the harm of NSSI behavior to adolescents, identification methods, and intervention

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Courtet, P. "A neurosciences based – semiology of suicidal behavior." European Psychiatry 33, S1 (2016): S49. http://dx.doi.org/10.1016/j.eurpsy.2016.01.915.

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The epidemiology, risk factors and biological basis of suicidal behaviors have been the object of an ever-increasing research in the last three decades. During this period, researchers all over the world have identified potential biomarkers of risk and developed several theories about the mechanisms leading to suicidal behavior. However, the lack of common terminology, instruments and cooperation has been a major deterrent. Today, the community has established the bases for this collaboration and evidence coming from neuroscientific studies can already be applied to the field of suicidology. W

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Dhankar, Abhinav, Kunal Kumar, Abhinit Kumar, et al. "Between Compassion and Collapse: Alcohol Intake and Mental Health Challenges in Caregivers of Patients with Suicidal Behavior." Journal of Neonatal Surgery 14, no. 10S (2025): 135–41. https://doi.org/10.52783/jns.v14.2772.

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Introduction: Suicidal behaviour poses significant public health concerns, not only for individuals but also for their caregivers, who often experience emotional distress. Alcohol use as a maladaptive coping strategy are underexplored in caregivers of individuals exhibiting suicidal behaviour . Method: This observational cross-sectional study was conducted from December 2023 to May 2024 at the Psychiatry Department of Sharda Hospital, Greater Noida. Eighty caregivers of patients with suicidal behaviour were enrolled using a convenience sampling method. Participants were assessed using a self-d

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Lopez-Castroman, J., I. Jaussent, S. Beziat, et al. "Increased severity of suicidal behavior in impulsive aggressive patients exposed to familial adversities." Psychological Medicine 44, no. 14 (2014): 3059–68. http://dx.doi.org/10.1017/s0033291714000646.

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BackgroundThe mechanisms by which childhood abuse and family history of suicidal behavior (FHS) lead to an increased risk of suicidal behavior are still unknown. Impulsive aggression may play an intermediate role. We investigated whether greater scores for aggression and impulsivity might be associated with the effects of FHS and/or childhood abuse on the severity of suicidal behavior.MethodWe examined the scores of three scales measuring impulsive aggression in a sample of 696 suicide attempters. We compared the highest and lowest scores with regard to reports of childhood abuse and FHS using

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Kumar Yadav, Pradeep. "Contemporary Relationships: The Potential Risk of Affection and Suicidal Ideation." International Journal of Forensic Sciences 9, no. 4 (2024): 1–11. http://dx.doi.org/10.23880/ijfsc-16000411.

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Introduction: Modern relationship dynamics, influenced by factors such as social media, changing gender roles, and societal expectations, have given rise to unique challenges in understanding the intersection of love addiction and suicide risk. This introduction sets the stage for thoroughly examining existing research, highlighting the need to address this pressing issue and its potential implications for mental health interventions. Aim: This article analyzes contemporary relationships, revealing their potential link to increased vulnerability to suicidal thoughts in modern romantic relation

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Vasyagina, Natalia N., Elena S. Barinova, Elena N. Grigoryan, and Natalia I. Shempeleva. "Relationship between the risk of suicidal behavior and personal resources of students." National Psychological Journal 49, no. 1 (2023): 114–25. http://dx.doi.org/10.11621/npj.2023.0110.

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Background. According to the Federal State Statistics Service, in 2021 the number of teenage suicides in Russia increased by 20% compared to the years. Being caused by non-specific mechanisms of influence produced by a variety of barely controllable factors, both individual and interpersonal, and socio-economic, suicide among minors is one of the most serious problems requiring immediate solution. However, not every teenager who is under the influence of adverse factors develops anti-vital moods and develops the risk of suicidal behavior, and therefore it is an important task to determine the

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Bashirzadeм, K. A., and M. Y. Narov. "Suicidal behavior in participants of the special military operation." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 5 (April 28, 2025): 662–68. https://doi.org/10.33920/med-01-2505-11.

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In the context of a special military operation (SMO), the relevance of measures for the prevention, support and rehabilitation of military personnel increases every day, as the proportion of those returning from the combat zone increases in the population. It is known that one of the main markers of completed suicide is the presence of suicide attempts in the anamnesis. Thus, to effectively solve the problem of suicides among military personnel, it is necessary to study in detail the characteristics of suicidal behavior in this category of citizens. The purpose of the study was to study the st

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Ovchinnikov, Anatoly A., Aklima N. Sultanova, Ekaterina I. Borodina, Vera V. Zelenskaia, and Tatyana Yu Sycheva. "Strategies of overcoming and the level of viability at adolescents’ suicide behavior." Neurology Bulletin L, no. 1 (2023): 28–32. http://dx.doi.org/10.17816/nb119891.

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The problem of identifying suicide risk in adolescents, especially among high-risk subgroups, requires a multifactor analysis not only of etiological factors, but also individual psychological characteristics of suicides, which could help significantly in predicting risk. The purpose of this work was to study the protective-coping strategies of adolescents prone to suicidal behavior and to analyze the effect of the level of viability on the dominance of certain protections and copings. It has been revealed that adolescents with high suicide risk are more likely to use the defense mechanisms re

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