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Journal articles on the topic 'Mediastinal lymphadenopathy'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Scano, Valentina, Alessandro Giuseppe Fois, Andrea Manca, et al. "Role of EBUS-TBNA in Non-Neoplastic Mediastinal Lymphadenopathy: Review of Literature." Diagnostics 12, no. 2 (2022): 512. http://dx.doi.org/10.3390/diagnostics12020512.

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Mediastinal lymphadenopathy is a condition in which one or more mediastinal lymph nodes are enlarged for malignant or benign causes, generally more than 10 mm. For a long time, the only way to approach the mediastinum was surgery, while in last decades endoscopic techniques gained their role in neoplastic diseases. At the present time, EBUS is the technique of choice for studying the mediastinum in the suspicion of cancer, while there are not strong indications in guidelines for the study of benign mediastinal lymphadenopathy. We reviewed the literature, looking for evidence of the role of EBU

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2

Gadour, Eyad, Sarah Al Ghamdi, Bogdan Miutescu, et al. "Linear endoscopic ultrasound: Current uses and future perspectives in mediastinal examination." World Journal of Gastroenterology 30, no. 33 (2024): 3803–9. http://dx.doi.org/10.3748/wjg.v30.i33.3803.

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This editorial elaborates on the current and future applications of linear endoscopic ultrasound (EUS), a substantial diagnostic and therapeutic modality for various anatomical regions. The scope of endosonographic assessment is broad and, among other factors, allows for the evaluation of the mediastinal anatomy and related pathologies, such as mediastinal lymphadenopathy and the staging of central malignant lung lesions. Moreover, EUS assessment has proven more accurate in detecting small lesions missed by standard imaging examinations, such as computed tomography or magnetic resonance imagin

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3

Hainaut, P., A. Monthe, V. Lesage, and B. Weynand. "Tuberculous Mediastinal Lymphadenopathy." Acta Clinica Belgica 53, no. 2 (1998): 114–16. http://dx.doi.org/10.1080/17843286.1998.11754153.

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4

Sharma, Pawan, Manish Bhargav, and Shivani Saklani. "Tubercular lymphadenopathy." International Journal of Research in Medical Sciences 13, no. 7 (2025): 3048–51. https://doi.org/10.18203/2320-6012.ijrms20252048.

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Tubercular mediastinal lymphadenopathy is a condition characterized by the abnormal enlargement of lymph nodes in the mediastinum also known as tuberculous lymphadenitis which can be acquired from close contact with an infected person. Mycobacterium tuberculli is one of the main causative agents of this dreadful infectious disease. The symptoms usually present are weakness or fatigue, weight loss, chills, fever, and sweating at night. After ruling out the clinical diagnosis it is treated in 2 phases i. e.; intensive phase or the initial phase and continuation phase followed by initial phase. I

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5

BOUSSAFASAF, Achour, Amira Yasmine CHAOUI, and Mansour FEKKAK. "Video-assisted-mediasinoscopy as an outpatient procedure in the management of mediastinal lymphadenopathy." Batna Journal of Medical Sciences (BJMS) 11, no. 2 (2024): 141–44. https://doi.org/10.48087/bjmsoa.2024.11203.

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Introduction. The mediastinum is a complex and dangerous anatomical region. Access to deep mediastinal lymphadenopathy is a challenge in terms of positive diagnosis, extension assessment and prognosis for patients with thoracic or extra thoracic lymphadenopathy. Despite advances in endoscopy, and in imaging and molecular biology in the diagnosis of mediastinal lymphadenopathy, the fear from severe causes is still a major problem for healthcare providers. The use of histological analysis can resolve this problem. The aim of this work is to assess the determining role of videomediasinoscopy (VAM

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6

Vaid, N., C. E. Butler, C. S. Miller, S. Karim, and C. E. Collins. "Haematemesis with mediastinal lymphadenopathy." Gut 56, no. 12 (2007): 1684. http://dx.doi.org/10.1136/gut.2006.108472.

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7

Kutmah, Kheder, and Azmi Draw. "Rapidly developing Mediastinal Lymphadenopathy." Chest 126, no. 4 (2004): 951S. http://dx.doi.org/10.1378/chest.126.4_meetingabstracts.951s-a.

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8

Vaid, N., C. E. Butler, C. S. Miller, S. Karim, and C. E. Collins. "Haematemesis with mediastinal lymphadenopathy." Case Reports 2009, feb04 1 (2009): bcr2006108472. http://dx.doi.org/10.1136/bcr.2006.108472.

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9

Meta-Jevtović, Ivana, and Miroslav Tomović. "Video-assisted thoracoscopic surgery (VATS) in sarcoidosis involving hilus and mediastinal lymphadenopathy." Medicinski casopis 55, no. 3 (2021): 108–12. http://dx.doi.org/10.5937/mckg55-31905.

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Sarcoidosis is a multiorgan, granulomatous disease of unknown etiology. The diagnosis is determined based on clinical and radiographic findings of hilar and or mediastinal lymphadenopathy with or without focal lesions in the lung parenchyma. It is confirmed according to pathohistological findings of a non-caseous granuloma on biopsied lymph nodes or lung parenchyma obtained by standard bronchoscopy. VATS procedures are used when it is impossible to confirm the disease using standard diagnostic methods. Mainly, it is applied in the case of sudden worsening of conditions. The application of VATS

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10

Bhatti, Faryal S., Amyn A. Malik, and Adeel A. Malik. "Presence of mediastinal lymphadenopathy in hospitalized Covid-19 patients in a tertiary care hospital in Pakistan–A cross-sectional study." PLOS ONE 18, no. 5 (2023): e0265865. http://dx.doi.org/10.1371/journal.pone.0265865.

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Background The aim of this study was to investigate the presence of mediastinal lymphadenopathy in hospitalized Covid-19 patients in a tertiary care hospital in the metropolitan city of Lahore, Pakistan from September 2020 till July 2021. Methods We retrospectively collected data of Covid-19 patients hospitalized from September 2020 till July 2021. Only those patients who tested PCR positive through a nasopharyngeal swab, were enrolled in the study. Patients’ whose data were missing were excluded from this study. Our exclusion criteria included patients who tested negative on Covid-19 PCR, pat

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11

Madasu, Anjan, Asim Noor Rana, Saleh Banat, Hani Humad, Rashid Mustafa, and Abdulrahman Mohd AlJassmi. "Langerhans Cell Histiocytosis in an Infant Mimicking a Lymphoma at Presentation." Case Reports in Hematology 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/670843.

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Langerhans cell histiocytosis (LCH) is a rare disorder characterized by proliferation and accumulation of clonal dendritic cells with varied clinical presentation and an unpredictable course. We report a 5-month-old infant with LCH who presented with severe respiratory distress, a large mediastinal mass, significant generalized lymphadenopathy, and hepatosplenomegaly. Lymphoma, especially T cell lymphoblastic lymphoma, can present with superior mediastinal syndrome needing urgent empirical therapy without biopsy. However, lack of response prompted a biopsy which confirmed it to be a case of LC

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12

Lähde, S., K. Hyrynkangas, J. Merikanto, R. Pokela, K. Jokinen, and P. Kärkölä. "Computed Tomography and Mediastinoscopy in the Assessment of Resectability of Lung Cancer." Acta Radiologica 30, no. 2 (1989): 169–73. http://dx.doi.org/10.1177/028418518903000210.

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In order to assess the potential of computed tomography (CT) of the mediastinum and mediastinoscopy in the staging of lung cancer, 125 patients were examined. Of these, 104 underwent thoracotomy, at which there was no evidence of mediastinal tumour involvement in 79 while 25 patients had signs of tumour spread. The sensitivity and specificity of CT were 87.0 per cent and 95.8 per cent, respectively, in the detection of direct tumour extension with a mediastinal mass. When lymph node enlargement was the sole finding, CT did not provide any differentiation between benign and malignant lymphadeno

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13

Shrestha, Rabin, and Dipen Kadaria. "Proteinaceous Lymphadenopathy: A Rare Cause of Mediastinal Lymphadenopathy." Chest 150, no. 4 (2016): 542A. http://dx.doi.org/10.1016/j.chest.2016.08.560.

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14

Yasar, Kucukardali, Gunturk Arzu, Ozturk Mehmet Akif, et al. "Is there a relationship between COVID-19 and sarcoidosis? A case report." Archives of Pulmonology and Respiratory Care 8, no. 1 (2022): 023–27. http://dx.doi.org/10.17352/aprc.000080.

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Mediastinal lymphadenopathy is rare in Coronavirus Disease-2019 (COVID-19) patients with mild clinical course. The frequency of lymphadenopathy increases in COVID-19 patients who develop Acute Respiratory Distress Syndrome (ARDS). In a 38-year-old male patient, mediastinal lymphadenopathy and asymptomatic pulmonary embolism were detected during the third week of COVID-19 infection at home. Sarcoidosis was diagnosed with a finding of non-caseating granulomas. Even if it is asymptomatic, pulmonary embolism should be considered, especially in COVID-19 patients with high C - Reactive Protein (CRP)

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15

Amer, Ahmed M., Khalid M. Kamel, Abdelghaffar A. Abdelghaffar, and Rana K. El Said. "Spectral Doppler in mediastinal lymphadenopathy." Egyptian Journal of Chest Diseases and Tuberculosis 74, no. 1 (2025): 45–53. https://doi.org/10.4103/ecdt.ecdt_56_24.

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Background Ultrasound is a minimally invasive diagnostic method that enables real-time sampling of the hilar and mediastinal lymph nodes. Aim To evaluate the role of spectral Doppler using endobronchial ultrasound (EBUS) in the differentiation of mediastinal lymph node lesions. Patients and methods The study was conducted at the Pulmonology Department, Faculty of Medicine, Cairo University and it was conducted between February 2023 and March 2024. The study was performed on 32 patients who had been referred to the Chest Department, Kasr El-Aini Hospital for clinical assessment; all of them hav

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16

Ustabasioglu, Fethi Emre, Cesur Samanci, Deniz Alis, Nilay Sengul Samanci, Osman Kula, and Deniz Cebi Olgun. "Apparent Diffusion Coefficient Measurement in Mediastinal Lymphadenopathies: Differentiation between Benign and Malignant Lesions." Journal of Clinical Imaging Science 7 (March 6, 2017): 12. http://dx.doi.org/10.4103/jcis.jcis_84_16.

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Objectives:We aimed to prospectively assess the diagnostic value of apparent diffusion coefficient (ADC) measurement in the differentiation of benign and malignant mediastinal lymphadenopathies.Materials and Methods:The study included 63 consecutive patients (28 women, 35 men; mean age 59.3 years) with 125 mediastinal lymphadenopathies. Echoplanar diffusion-weighted magnetic resonance imaging of the mediastinum was performed with b-factors of 0 and 600 mm2/s before mediastinoscopy and mediastinotomy, and ADC values were measured. The ADC values were compared with the histological results, and

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17

Qayyum, Uzma, Naghmana Akhtar, Mudassir Iqbal, et al. "MEDIASTINAL LYMPHADENOPATHY AS A PREDICTOR OF WORSE OUTCOME IN SEVERE COVID-19 CASES." Journal of Ayub Medical College Abbottabad 34, no. 2 (2022): 321–25. https://doi.org/10.55519/jamc-02-9469.

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Background: This cross-sectional study is aimed at evaluating the association of mediastinal lymphadenopathy with COVID-19 prognosis in severe cases. Place and Duration of Study: Department of Medicine, Pak Emirates Military Hospital, Pakistan, from June to July 2020. Methods: One hundred and fifty (150) laboratory-confirmed SARS CoV-2 infected, severe cases in Intensive Care Unit/ High Dependency Unit were included. These cases were divided into two categories, i.e., with and without mediastinal lymphadenopathy on High Resolution Computed Tomography chest. The two categories were compared on

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18

Andronikou, Savvas, Dirk Johannes Van der Merwe, Pierre Goussard, Robert P. Gie, and Nicolette Tomazos. "Usefulness of lateral radiographs for detecting tuberculous lymphadenopathy in children – confirmation using sagittal CT reconstruction with multiplanar cross-referencing." South African Journal of Radiology 16, no. 3 (2012): 87–92. http://dx.doi.org/10.4102/sajr.v16i3.288.

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Background. Diagnosis of pulmonary tuberculosis (PTB) in children remains difficult. Lateral chest radiographs are frequently used to facilitate diagnosis, but interpretation is variable. In this study, lateral chest radiographs (CXRs) are evaluated against sagittal CT reconstructions for the detection of mediastinal lymphadenopathy.  Aim. To correlate suspected lymphadenopathy on lateral CXR with sagittal CT reconstructions and determine which anatomical group of lymph nodes contributes to each lateral CXR location.  Methods and materials. Thirty TB-positive children’s

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19

Chan, Hiang Ping, and Hwee Seng Yip. "Mediastinal Lymphadenopathy: Melioidosis Mimicking Tuberculosis." Tropical Medicine and Health 43, no. 2 (2015): 93–94. http://dx.doi.org/10.2149/tmh.2014-42.

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20

Haramati, Linda B., Alicia M. Cartagena, and John H. M. Austin. "CT Evaluation of Mediastinal Lymphadenopathy." Journal of Computer Assisted Tomography 19, no. 3 (1995): 375–78. http://dx.doi.org/10.1097/00004728-199505000-00007.

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21

Currie, Graeme P., and David Miller. "Endobronchial Ultrasound in Mediastinal Lymphadenopathy." American Journal of Respiratory and Critical Care Medicine 186, no. 3 (2012): 208–9. http://dx.doi.org/10.1164/rccm.201205-0911ed.

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22

Demos, T. C. "Mediastinal lymphadenopathy in mycoplasmal pneumonia." American Journal of Roentgenology 162, no. 6 (1994): 1499–500. http://dx.doi.org/10.2214/ajr.162.6.8192050.

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23

Kavanagh, Richard, and Diarmuid Smith. "Bilateral Hilar and Mediastinal Lymphadenopathy." New England Journal of Medicine 364, no. 24 (2011): 2342. http://dx.doi.org/10.1056/nejmicm1006314.

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24

Karanth, Nikhil, and Ali Nawras. "EUS-FNA of Mediastinal Lymphadenopathy." American Journal of Gastroenterology 101 (September 2006): S526—S527. http://dx.doi.org/10.14309/00000434-200609001-01375.

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25

Demko, I. V., E. A. Sobko, N. V. Gordeeva, et al. "Mediastinal lymphadenopathy: differential diagnosis challenges." Profilakticheskaya meditsina 26, no. 1 (2023): 89. http://dx.doi.org/10.17116/profmed20232601189.

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26

van Zanten, T. E. G., R. P. Golding, and A. H. M. Taets ven Amerongen. "Osteosarcoma with calcific mediastinal lymphadenopathy." Pediatric Radiology 17, no. 3 (1987): 258–59. http://dx.doi.org/10.1007/bf02388180.

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27

Vasudevan, A., and GayathriAnur Ramakrishnan. "Mediastinal lymphadenopathy – A case report." Journal of Association of Pulmonologist of Tamil Nadu 6, no. 1 (2023): 29. http://dx.doi.org/10.4103/japt.japt_10_23.

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28

Soumya, Vasantha Somarajan, K. A. Ameer, Rajalakshmi Arjun, Sujith Varghese Abraham, Sanowfer Mohammed, and Arjun Padmanabhan. "Atypical Presentation of an Unusual Infection." Pulmon 26, no. 1 (2024): 17–19. http://dx.doi.org/10.4103/pulmon.pulmon_4_24.

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Abstract Melioidosis presents with a diverse range of clinical manifestations affecting various organs, with pneumonia being the most common pulmonary presentation. Isolated mediastinal lymphadenopathy with fever as presentation is rare. Here, we present a case of melioidosis, presenting as pyrexia of unknown origin with mediastinal lymphadenopathy.

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29

Deepak, T. H., Ananthu Joseph, S. Santhakumar, and J. Venugopal. "An Atypical Etiology for Granulomatous Mediastinal Lymphadenopathy in an Immunocompetent Adult Male." Pulmon 26, no. 1 (2024): 23–25. http://dx.doi.org/10.4103/pulmon.pulmon_10_24.

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Abstract Nontuberculous mycobacteria (NTM) are widely distributed microorganisms that have the potential to cause severe illness in humans, especially those with compromised immune systems. In adults, the disease mainly manifests as chronic pulmonary disease. Few case reports are available on lymphadenopathy caused by nontubercular mycobacterium in children, primarily affecting the cervical lymph nodes. However, it is exceptionally rare for an immunocompetent adult to develop mediastinal lymphadenopathy due to NTM infection. We present a case of posttubercular fibrocavitary lung disease with m

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30

Low, Su Ying, Mariko S. Koh, Thun How Ong, Ghee Chee Phua, and Devanand Anantham. "Use of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) in the Diagnosis of Granulomatous Mediastinal Lymphadenopathy." Annals of the Academy of Medicine, Singapore 43, no. 5 (2014): 250–54. http://dx.doi.org/10.47102/annals-acadmedsg.v43n5p250.

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Introduction: This study assessed the clinical utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for the diagnosis of suspected granulomatous mediastinal lymphadenopathy. Materials and Methods: Retrospective chart review of all patients who underwent EBUS-TBNA for suspected granulomatous mediastinal lymphadenopathy at Singapore General Hospital between December 2008 and December 2011 inclusive. Results: Over a period of 3 years, a total of 371 patients underwent EBUS-TBNA of whom 33 (9%) had the procedure performed for evaluation of suspected granulomatous

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31

Kim, Dohun, Yong-Moon Lee, Si-Wook Kim, Jong-Won Kim, and Jong-Myeon Hong. "Primary Pulmonary Amyloidosis with Mediastinal Lymphadenopathy." Korean Journal of Thoracic and Cardiovascular Surgery 49, no. 3 (2016): 218–20. http://dx.doi.org/10.5090/kjtcs.2016.49.3.218.

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32

Baikunje, Nandakishore, Giridhar Belur Hosmane, and Sunil Kumar Y. "Endobronchial Ultrasound in Evaluating Mediastinal Lymphadenopathy." Journal of Health and Allied Sciences NU 11, no. 03 (2021): 201–3. http://dx.doi.org/10.1055/s-0041-1725241.

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AbstractTuberculosis can involve most of the body parts, and tubercular lymphadenitis is common. But isolated involvement of mediastinal lymph nodes without lung parenchymal involvement is rare in adults. A 45-year-old lady presented with subcarinal lymph node enlargement. A conventional transbronchial needle aspiration done at a local hospital was inconclusive. Endobronchial ultrasound-guided transbronchial needle aspiration was done. Cytology showed epithelioid histiocytes and caseous necrosis. Stain for acid-fast bacilli and cartridge-based nucleic acid amplification test for tuberculosis w

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33

DEVI, K., and M. MODI. "ISOLATED MEDIASTINAL LYMPHADENOPATHY: A GREAT DECEPTION." Chest 161, no. 6 (2022): A417. http://dx.doi.org/10.1016/j.chest.2021.12.447.

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34

Bhatt, Naveen, and Nidhi Bhatt. "Mediastinal Tuberculous Lymphadenopathy Presenting with Dysphagia." Southern Medical Journal 100, no. 7 (2007): 728–29. http://dx.doi.org/10.1097/smj.0b013e31804855a9.

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35

MAHARAJ, DASHMEET, JUSTINE KO, and PRAVACHAN HEGDE. "HISTIOCYTIC SARCOMA PRESENTING AS MEDIASTINAL LYMPHADENOPATHY." CHEST 166, no. 4 (2024): A3614—A3615. http://dx.doi.org/10.1016/j.chest.2024.06.2159.

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36

Agarwal, Poojan, Gunjan Mangla, and Pooja Bakshi. "Primary amyloidosis presenting as mediastinal lymphadenopathy." Current Medicine Research and Practice 14, no. 4 (2024): 186. http://dx.doi.org/10.4103/cmrp.cmrp_116_24.

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37

Burgei, Jonathan, Katie M. Alsheimer, Julia Lantry, and Boyd Hehn. "Mediastinal lymphadenopathy due to VEXAS syndrome." BMJ Case Reports 17, no. 8 (2024): e261179. http://dx.doi.org/10.1136/bcr-2024-261179.

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Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is a rare disease first reported in 2020, most commonly seen in men aged 56–75 years old. Common clinical features include skin lesions (83.5%), fever (63.6%), relapsing chondritis (36.4%), venous thrombosis (34.7%) and lymph node enlargement (33.9%). The patient is a man in his 40s who presented with testicular and lower extremity pain, followed by a rash and bicytopenia. He was initiated on corticosteroids and sulfasalazine. He was found to have mediastinal lymphadenopathy and underwent an endobronchial ultrasound and

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38

Kalsdorf, Barbara, and Christoph Lange. "Tuberculous mediastinal lymphadenopathy: Reaching the target." Respirology 24, no. 7 (2019): 622–23. http://dx.doi.org/10.1111/resp.13536.

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39

Iyengar, K. B., C. Udyavara Kudru, S. Kaniyoor Nagiri, and A. C. K. Rao. "Tuberculous mediastinal lymphadenopathy in an adult." Case Reports 2014, jan13 1 (2014): bcr2013200718. http://dx.doi.org/10.1136/bcr-2013-200718.

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40

Staszak, Jessica K., Polina Zmijewski, Sandra Arnold, Bindiya Bagga, and Regan F. Williams. "Mediastinal Lymphadenopathy in Children With Histoplasmosis." Journal of Surgical Research 244 (December 2019): 558–65. http://dx.doi.org/10.1016/j.jss.2019.06.062.

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41

Alcolea, S., A. Santiago Recuerda, and M. C. Prado. "Cryptogenic Organizing Pneumonia and Mediastinal Lymphadenopathy." Archivos de Bronconeumología ((English Edition)) 40, no. 8 (2004): 384. http://dx.doi.org/10.1016/s1579-2129(06)60326-1.

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42

Hughes, P., and C. McGavin. "Recurrent laryngeal palsy and mediastinal lymphadenopathy." Respiratory Medicine 89, no. 8 (1995): 584. http://dx.doi.org/10.1016/0954-6111(95)90166-3.

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43

Sharma, Malay. "Combined Imaging for Benign Mediastinal Lymphadenopathy." Chest 140, no. 2 (2011): 558–59. http://dx.doi.org/10.1378/chest.11-0455.

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44

Adachi, Takashi, Masashi Nakahata, Suzuko Moritani, Hiroatsu Iida, and Kenji Ogawa. "Enlarging mediastinal/hilar lymphadenopathy with calcification." Clinical Case Reports 4, no. 2 (2015): 212–13. http://dx.doi.org/10.1002/ccr3.451.

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45

Gogulakrishnan, R., S. Jayakumar, H. Subramony, and R. Narasimhan. "Melioidosis Presenting as Isolated Mediastinal Lymphadenopathy." Journal of Association of Pulmonologist of Tamil Nadu 1, no. 2 (2018): 68. http://dx.doi.org/10.4103/2772-6355.309277.

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46

Meral, Mehmet, Metin Akgun, Hasan Kaynar, et al. "Mediastinal Lymphadenopathy due to Mycobacterial Infection." Japanese Journal of Infectious Diseases 57, no. 3 (2004): 124–26. https://doi.org/10.7883/yoken.jjid.2004.124.

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47

Tseng, Ting-Chun, Hung-Pin Chan, Daniel Hueng-Yuan Shen, and Chang-Chung Lin. "IgG4-Related Lymphadenopathy Mimicking Mediastinal Lymph Node Metastasis of Lung Cancer on 18F-FDG PET/CT." Diagnostics 15, no. 1 (2024): 41. https://doi.org/10.3390/diagnostics15010041.

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We report a case of a 73-year-old man with minimally invasive lung adenocarcinoma, post-resection, evaluated with 18F-FDG PET/CT for suspected disease progression. Imaging showed increased FDG uptake in the right lower lung mass and systemic lymphadenopathy (mediastinal, supraclavicular, axillary, paraaortic, and iliac regions). The appearance of a stable lymph node and a clinical history of IgG4 lymphadenopathy suggested an inflammatory process, although malignancy in the lung mass and mediastinal nodes could not be excluded. Lobectomy confirmed the presence of lung adenocarcinoma, while radi

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48

Thapa, Bibhusal. "Mediastinoscopy: safety and utility Cervical mediastinoscopy: assessing mediastinal lymphadenopathy at Manmohan Cardio-thoracic Vascular and Transplant center." Journal of Society of Surgeons of Nepal 19, no. 2 (2016): 7–9. http://dx.doi.org/10.3126/jssn.v19i2.24542.

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Introduction: Mediastinoscopy is considered essential in staging of lung cancer and evaluation of mediastinal lymphadenopathy and masses. This facility has only recently been available at our center. We review our initial experience and analyse its safety and utility in our setting. Methods: Retrospective analysis of data of all patients who underwent cervical mediastinoscopy at Manmohan Cardio-thoracic Vascular and Transplant Center (MCVTC) was done. Demographic, clinical and perioperative data were recorded. Concordance of pre and post-operative diagnosis was studied. Results: Be

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49

Aljehani, Yasser, Yasser Elghoneimy, Zeead Alghamdi, et al. "Efficacy of Mediastinoscopy in Patients With Isolated Mediastinal Lymphadenopathy." Medical Archives 77, no. 6 (2023): 477. http://dx.doi.org/10.5455/medarh.2023.77.477-481.

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Background: Since its introduction in 1959 by Carlens [1], Mediastinoscopy has been, for long, used for assessment of the mediastinum (superior and middle) for establishing a histological diagnosis of mediastinal masses of undefined cause, and for Lung carcinomas staging. The use of Mediastinoscopy has been decreasing lately due to the introduction of other less invasive techniques (e.g., endoscopic ultrasound-directed fine needle aspiration cytology), however, it is still a cheap and effective tool that can be utilized in underprivileged centers. Objective: To emphasize how does Mediastinosco

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50

Kho, Sze Shyang, Chun Ian Soo, Mona Zaria Nasaruddin, Kah Wai Ngan, and Jamalul Azizi Abdul Rahaman. "Multimodal linear endobronchial ultrasound guided mediastinal lymph node biopsy in the diagnosis of isolated mediastinal lymphadenopathy." Proceedings of Singapore Healthcare 31 (June 2022): 201010582211116. http://dx.doi.org/10.1177/20101058221111655.

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Abstract:

Isolated mediastinal lymphadenopathy represents a common diagnostic dilemma whereby morphological analysis of tissue specimens are frequently needed to ascertain the diagnosis. Cryobiopsy by linear endobronchial ultrasound (EBUS) guidance had recently been described in literature. We described a multimodality biopsy approach of a case of isolated tuberculous mediastinal lymphadenitis in which we employed the 22-gauge transbronchial aspiration needle, mini-forceps and a flexible cryoprobe sequentially. We aim to highlight the novel technique of linear EBUS guided cryobiopsy in acquiring superio

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