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Journal articles on the topic 'Mediastinal widening'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

KARNATH, BERNARD, and ATHER SIDDIQI. "Acute Mediastinal Widening." Southern Medical Journal 95, no. 10 (2002): 1222–25. http://dx.doi.org/10.1097/00007611-200210000-00026.

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2

KARNATH, BERNARD, and ATHER SIDDIQI. "Acute Mediastinal Widening." Southern Medical Journal 95, no. 10 (2002): 1222–25. http://dx.doi.org/10.1097/00007611-200295100-00027.

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3

Ruan, S. Y., and J. S. Jerng. "Chest tightness and mediastinal widening." Canadian Medical Association Journal 179, no. 3 (2008): 255–56. http://dx.doi.org/10.1503/cmaj.080737.

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4

Chawla, RakeshK, Arun Madan, Aditya Chawla, and Kiran Chawla. "Mediastinal widening: An interesting quiz." Lung India 33, no. 1 (2016): 95. http://dx.doi.org/10.4103/0970-2113.173079.

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5

Dua, Ruchi, and Ankit Singhal. "A cause of mediastinal widening." Lung India 33, no. 4 (2016): 453. http://dx.doi.org/10.4103/0970-2113.184931.

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6

Jindal, Nishant, Charanpreet Singh, and Pankaj Malhotra. "Unusual cause of mediastinal widening." BMJ Case Reports 13, no. 6 (2020): e236180. http://dx.doi.org/10.1136/bcr-2020-236180.

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7

Jochelson, M., P. Mauch, J. Balikian, D. Rosenthal, and G. Canellos. "The significance of the residual mediastinal mass in treated Hodgkin's disease." Journal of Clinical Oncology 3, no. 5 (1985): 637–40. http://dx.doi.org/10.1200/jco.1985.3.5.637.

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The chest roentgenograms of 65 patients treated for Hodgkin's disease with mediastinal adenopathy were analyzed retrospectively to determine the incidence and significance of residual mediastinal abnormality after treatment. All patients were treated with radiation therapy, and 36 patients received additional chemotherapy. On completion of treatment, 57 (88%) of the 65 patients had some residual mediastinal abnormality. These were either minimal changes in the mediastinal shadow in 30 patients or a widening greater than 6 cm in 27 patients. In the latter group, 11 (40%) of 27 patients continue

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8

Woodring, JH, and RA Rhodes. "Posterosuperior mediastinal widening in aortic coarctation." American Journal of Roentgenology 144, no. 1 (1985): 23–25. http://dx.doi.org/10.2214/ajr.144.1.23.

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9

Mohapatra, PrasantaR, Kranti Garg, Chikkahonnaiah Prashanth, and Rupali Lahoria. "Pleural effusion presenting as mediastinal widening." Lung India 30, no. 4 (2013): 354. http://dx.doi.org/10.4103/0970-2113.120621.

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10

Raskin, Jo, and Pascal Van Bleyenbergh. "Normalization of mediastinal widening after successful treatment of mediastinal tuberculosis." Acta Clinica Belgica 71, no. 4 (2016): 269–70. http://dx.doi.org/10.1080/17843286.2016.1175704.

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11

T., Nithin K., Vikas Kumar, and P. Prasanth. "A case report on incidental finding of thymoma as anterior mediastinal mass." International Journal of Basic & Clinical Pharmacology 8, no. 6 (2019): 1441. http://dx.doi.org/10.18203/2319-2003.ijbcp20192217.

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Thymomas are rare tumors in the anterior mediastinum, representing 50% of anterior mediastinal masses and about 20-30% of all mediastinal tumors. They are of unknown etiology; about 50% of patients with thymomas are diagnosed incidentally with chest radiography. Thymoma is classified into different stages, which determine the prognosis and type of management, the standard primary treatment for these tumors is Thymectomy. We present a case of 55-year female presented with shortness of breath, cough with expectoration and fever for past ten days. Chest x-ray revealed mediastinal widening. CECT c

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12

Peylan-Ramu, N., T. B. Haddy, E. Jones, K. Horvath, M. A. Adde, and I. T. Magrath. "High frequency of benign mediastinal uptake of gallium-67 after completion of chemotherapy in children with high-grade non-Hodgkin's lymphoma." Journal of Clinical Oncology 7, no. 12 (1989): 1800–1806. http://dx.doi.org/10.1200/jco.1989.7.12.1800.

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We observed increased gallium-67 uptake in the mediastinum after completion of chemotherapy in 10 of 62 patients with non-Hodgkin's lymphoma. All 10 were under 15 years of age, yielding a frequency of 43% in this age group. The interval between cessation of chemotherapy and the development of increased gallium-67 uptake ranged from 1 to 8 months, and the abnormality persisted for 2 to 59 months. Serial chest x-rays were performed in all patients, and four of the 10 had transient widening of the mediastinum that remained within normal limits for the children's ages. Three patients had chest com

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13

Hajar, Khaoulani, Dr Darfaoui Meryem Amenzouy, Pr Bouktib, et al. "Primary Myxoid Liposarcoma of the Middle Mediastinum About a Case (Primary Myxoid Liposarcoma of the Middle Mediastinum)." SAS Journal of Surgery 10, no. 10 (2024): 1135–37. http://dx.doi.org/10.36347/sasjs.2024.v10i10.008.

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Myxoid liposarcomas "LPS" are rare tumors, especially in their mediastinal location. We report a case of a myxoid liposarcoma of the middle mediastinum, in a 51-year-old patient, with no particular pathological history, admitted with a NYHA stage V dyspnea picture. A chest X-ray made objectifying a mediastinal widening of water density, with external edges convex towards the lung and internal edges merged with the mediastinum, the chest CT scan of which links it to a lesion process of the middle mediastinum well defined with clear heterogeneous contours of mixed tissue, fat and water density w

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14

Isaacs, Larry M., Bernard Kotton, Modesto M. Peralta, et al. "Fatal Mediastinal Abscess from Upper Respiratory Infection." Ear, Nose & Throat Journal 72, no. 9 (1993): 620–31. http://dx.doi.org/10.1177/014556139307200911.

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Suppurative mediastinitis following neck infection is an uncommon entity that carries a 40% mortality. It is most commonly associated with esophageal perforation or odontogenic abscess. The rapidity of spread has been attributed to dependent drainage from the neck into the mediastinum, negative intrathoracic pressure, and synergistic necrotizing bacterial growth. Cultures obtained usually grow streptococci and/or Bacteroides. We report the case of a 34-year-old woman with an upper respiratory infection who subsequently was found to have a para-/retropharyngeal and mediastinal abscess. Septic s

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15

Michel, F., J. P. Gilbeau, C. Six, J. L. Michaux, and A. Delannoy. "Progressive Mediastinal Widening After Therapy For Hodgkin’s Disease." Acta Clinica Belgica 50, no. 5 (1995): 282–87. http://dx.doi.org/10.1080/17843286.1995.11718462.

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16

Haddon, M. J., D. K. Nakayama, and K. S. Oh. "Superior mediastinal widening from traumatic cerebrospinal fluid leak." Pediatric Radiology 20, no. 3 (1990): 190. http://dx.doi.org/10.1007/bf02012970.

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17

Orlandi, Ester, Mario Lazzarino, Ercole Brusamolino, et al. "RESIDUAL MEDIASTINAL WIDENING FOLLOWING THERAPY IN HODGKIN'S DISEASE." Hematological Oncology 8, no. 3 (2006): 125–31. http://dx.doi.org/10.1002/hon.2900080303.

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18

Oliveira, Karen Fernandes de, Marcio Maciel Rodrigues, Gesner Pereira Lopes, Renan Sandoval de Almeida, Juliana Lopes Lusvarghi, and João Paulo Vieira dos Santos. "Massive thymoma of the mid-posterior mediastinum: an unprecedented case in a young adult." Radiologia Brasileira 49, no. 6 (2016): 403–5. http://dx.doi.org/10.1590/0100-3984.2014.0025.

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Abstract We report an unprecedented case of ectopic thymoma in a young adult. A 33-year-old male presented with a 10-day history of non-productive cough and fever. Investigation revealed mediastinal widening without pulmonary involvement. Computed tomography showed a large mass-14.8 × 10.8 × 8.4 cm-in the mid-posterior mediastinum, and a biopsy obtained by video-assisted thoracoscopy indicated that the mass was a tumor. Immunohistochemistry showed combined thymoma type AB1. Because of the considerable proportions of the tumor and its close proximity to major structures, the patient was treated

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19

Karaborni, Bochra, Hela Kamoun, Hadhemi Rejeb, Imene Bouassida, Hanene Smadhi, and Leila Fekih. "Case Report: Atypical Localization of a Pulmonary Hydatid Cyst." F1000Research 14 (March 12, 2025): 285. https://doi.org/10.12688/f1000research.162741.1.

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Hydatid disease is a significant public health concern in endemic regions. The liver and lungs are the primary sites of infection, and mediastinal localization is extremely rare. We report the case of a 34-year-old patient with no significant medical history, who presented with right basithoracic pain and exertional dyspnea. Chest radiography revealed mediastinal widening, and further imaging with chest CT and magnetic resonance imaging (MRI) identified a right anterosuperior multivesicular mediastinal hydatid cyst adjacent to the pericardium. The patient underwent surgery with favorable posto

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20

Hanna, Michael, Ghada Elshimy, Medhat Ismail, and Mourad Ismail. "An Unusual Benign Cause of an Alarming Finding on Chest-X ray: A Case Report of Widened Mediastinum due to Rare Congenital Abnormality (Azygos Vein Continuation of Inferior Vena Cava)." Case Reports in Critical Care 2019 (December 9, 2019): 1–4. http://dx.doi.org/10.1155/2019/3457495.

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Acute widened mediastinum is an alarming finding. It has many possible differential diagnoses; aortic dissection (AD) is considered one that carries catastrophic outcomes. AD is relatively uncommon; it requires early and accurate diagnosis and treatment for better patient survival. However, acute mediastinal widening also can be present in more benign conditions. We report a case of a 50-year-old African American female with postoperative shortness of breath; initial imaging studies revealed an acute widened mediastinum, but on further management with diuresis and follow-up imaging, she was di

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21

Taleb, N., E. Salloum, and E. Brihi. "Persistent Stable Mediastinal Widening after Chemotherapy in Hodgkin's Disease." Acta Oncologica 27, no. 1 (1988): 75. http://dx.doi.org/10.3109/02841868809090323.

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22

Kota, SK, SK Kota, S. Jammula, and PR Tripathy. "Mediastinal widening in asymptomatic type 1 diabetes mellitus patient." Journal of Diabetology 3, no. 2 (2012): 1. http://dx.doi.org/10.4103/2078-7685.198061.

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23

Pollack, Ian I. F., Dachling Pang, and Walter A. Hall. "Subarachnoid-Pleural and Subarachnoid-Mediastinal Fistulae." Neurosurgery 26, no. 3 (1990): 519–25. http://dx.doi.org/10.1227/00006123-199003000-00023.

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Abstract Subarachnoid-pleural fistula and subarachnoid-mediastinal fistula are rare complications of chest trauma. One case each of subarachnoid-mediastinal fistula and subarachnoid-pleural fistula is described. Both patients were young children who suffered severe longitudinal distraction injuries to their thoracic spine and exhibited complete cord transection without radiographic evidence of vertebral column injury. Progressive mediastinal widening and enlarging pleural effusion in the absence of angiographic evidence of aortic injury suggested the diagnosis of an intrathoracic cerebrospinal

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24

Serisana Wasita, I. Kadek, Ayu Setyorini M. Mayangsari, and Ni Putu Siadi Purniti. "Mediastinal Lobular Capillary Haemangioma in Children with Severe Airway Obstruction Symptom: A Case Report." International Journal of Research and Review 9, no. 12 (2022): 241–46. http://dx.doi.org/10.52403/ijrr.20221225.

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Background: Lobular capillary haemangioma (LCH) is a polypoid form of capillary haemangioma occurring on the skin and mucosal surfaces. While LCH of the oral and nasal cavity is well-known entity, mediastinal localization is a rare case. In children, LCH is frequently benign. Case illustration: A two month age baby girl experienced recurrent inspiratory stridor since she was 42 days-old and diagnosed as laryngomalacia. Due to the widening of mediastinal area from chest x-ray, a chest CT-scan was conducted and showed a mass in the mediastinal area. A sternotomy was done and found mass filled th

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25

Young, C. M. "Mediastinal assessment in traumatic rupture of the aorta." South African Journal of Radiology 1, no. 2 (1996): 8–11. http://dx.doi.org/10.4102/sajr.v1i2.1612.

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The precise method for measuring mediastinal widening in thoracic trauma is poorly understood and too much emphasis is placed on it as the sole criterion for performing aortography. This review article describes the established methods of measurement and their limitations, and also discusses the importance of other signs pointing to aortic rupture such as blurring of the aortic knuckle and a subjective impression of mediastinal abnormality which are more helpful in determining the need for angiography.

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26

Al-Adsani, Afaf, Mohamed H. Dahniya, and Ahmed Al-Beltagi. "Mediastinal Widening due to Lipomatosis and Herniated Liver and Stomach." Annals of Saudi Medicine 20, no. 3-4 (2000): 288–90. http://dx.doi.org/10.5144/0256-4947.2000.288.

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27

Hoeffel, C., P. Fornes, Q. K. Nguyen, and J. C. Hoeffel. "Mediastinal Widening Due to Lipomatosis and Herniated Liver and Stomach." Annals of Saudi Medicine 21, no. 3-4 (2001): 258. http://dx.doi.org/10.5144/0256-4947.2001.258.

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28

Güney, B., G. Demirpolat, R. Savaş, and H. Alper. "An unusual cause of mediastinal widening: bilateral innominate vein aneurysms." Acta Radiologica 45, no. 3 (2004): 266–68. http://dx.doi.org/10.1080/02841850410004256.

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29

Bolesta, M. J., and H. H. Bohlman. "Mediastinal widening associated with fractures of the upper thoracic spine." Journal of Bone & Joint Surgery 73, no. 3 (1991): 447–50. http://dx.doi.org/10.2106/00004623-199173030-00016.

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30

Moskowitz, William B., Thomas J. Shula, and Richard M. Schieken. "Congenital aortic elongation: A rare cause of superior mediastinal widening." American Heart Journal 112, no. 6 (1986): 1328–29. http://dx.doi.org/10.1016/0002-8703(86)90372-8.

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31

Garg, RavindraK, Ravi Uniyal, Shweta Pandey, Neeraj Kumar, and HardeepS Malhotra. "Mediastinal Widening in a Patient with Paraplegia: An Unusual Cause." Neurology India 68, no. 5 (2020): 1201. http://dx.doi.org/10.4103/0028-3886.299151.

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32

Mukherjee, Rishav, and Sampurna Chowdhury. "Initial presentation of Hodgkin’s Lymphoma as Extradural Spinal Cord Compression: A case report." Asian Journal of Medical Sciences 11, no. 2 (2020): 101–3. http://dx.doi.org/10.3126/ajms.v11i2.27477.

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A 23 year old female presented with acute onset paraparesis. She denied any history of fever, weight loss or drenching night sweats. Neither did she have any obvious lymphadenopathy on general examination. Chest Xray was however suggestive of mediastinal widening and her MRI spine showed metastases with superior mediastinal SOL. Biopsy of this SOL ultimately revealed classical Hodgkin lymphoma. Thus this was a very unusual initial presentation of Hodgkin lymphoma presenting as Epidural Spinal Cord Compression. Hasenclever IPS score was 2. Patient was treated with radiotherapy followed by ABVD

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33

Rishav Mukherjee and Sampurna Chowdhury. "Initial presentation of Hodgkin’s Lymphoma as Extradural Spinal Cord Compression: A case report." Asian Journal of Medical Sciences 11, no. 2 (2020): 101–3. https://doi.org/10.71152/ajms.v11i2.3490.

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A 23 year old female presented with acute onset paraparesis. She denied any history of fever, weight loss or drenching night sweats. Neither did she have any obvious lymphadenopathy on general examination. Chest Xray was however suggestive of mediastinal widening and her MRI spine showed metastases with superior mediastinal SOL. Biopsy of this SOL ultimately revealed classical Hodgkin lymphoma. Thus this was a very unusual initial presentation of Hodgkin lymphoma presenting as Epidural Spinal Cord Compression. Hasenclever IPS score was 2. Patient was treated with radiotherapy followed by ABVD

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34

Sophiya, .T. Varghese* Catherin T. J. Alan James Sethu Sugathan S. Hemalatha K. Menaka and Dr. T. Sivakumar. "CASE REPORT ON MARFAN SYNDROME." Indo American Journal of Pharmaceutical Sciences 04, no. 11 (2017): 3947–50. https://doi.org/10.5281/zenodo.1042735.

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Marfan syndrome is a spectrum of disorder caused by a heritable genetic defect of connective tissue that has an autosomal dominant mode of transmission. The defect itself has been isolated to FBN1 gene on chromosome 15, which codes for connective tissue protein FIBRIN. A mutation result in an increase in protein called transforming growth factor ß. Abnormalities in this protein cause a myriad of distinct clinical problems, of which the musculoskeletal, cardiac and ocular system problems predominate. A case report on Marfan syndrome with mediastinal widening and sinus tachycardia was reported.

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35

Batta, Akash, Manphool Singhal, Atit A. Gawalkar, and Parminder Singh Otaal. "Unusual cause of mediastinal widening and atrial fibrillation: mediastinal lipomatosis with infiltration into the interatrial septum." BMJ Case Reports 14, no. 11 (2021): e246980. http://dx.doi.org/10.1136/bcr-2021-246980.

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36

Ryu, Kyung Nam, Dong Wook Sung, Sun Wha Lee, and Jae Hoon Lim. "Superior mediastinal widening from traumatic cerebrospinal fluid leak with spinal fracture." Journal of the Korean Radiological Society 27, no. 4 (1991): 473. http://dx.doi.org/10.3348/jkrs.1991.27.4.473.

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37

Kulkarni, AV, NC Purandare, S. Kulkarni, and SG Dua. "Isolated left innominate vein aneurysm: A rare cause of mediastinal widening." Journal of Postgraduate Medicine 57, no. 1 (2011): 40. http://dx.doi.org/10.4103/0022-3859.74286.

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38

Brown, G., and J. E. Husband. "Mediastinal widening — a valuable radiographic sign of superior vena cava thrombosis." Clinical Radiology 47, no. 6 (1993): 415–20. http://dx.doi.org/10.1016/s0009-9260(05)81063-3.

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39

Bhalla, Sanjeev, and Christine O. Menias. "Case of the Season: Infectious Pseudoaneurysm Presenting With Acute Mediastinal Widening." Seminars in Roentgenology 49, no. 2 (2014): 130–33. http://dx.doi.org/10.1053/j.ro.2014.03.001.

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40

Ivancev, K., A. Halldorsdottir, S. Laurin, et al. "Computed Tomography in the Diagnosis and Treatment of Mediastinal Abnormalities in Children." Acta Radiologica 29, no. 1 (1988): 115–20. http://dx.doi.org/10.1177/028418518802900123.

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Thirty-one children with mediastinal abnormalities—14 malignant lymphomas, 4 other primary malignancies, one metastatic and 12 benign lesions—were examined one or several times using CT, which proved to be effective especially for cysts (5 patients), ductus arteriosus aneurysm (2 patients), and intrathoracic liver (one patient). It also supplied important diagnostic information regarding the extent of disease in malignant thymoma (one patient), in neurinoma (one patient), and in Hodgkin's lymphoma (5 patients). It was found to be useful in the monitoring of treatment of patients with lymphomas

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41

Lohrenz, Christina, Daniel Rückner, Olof Wintzer, Walter Gross-Fengels, and Stefan Meierling. "Large left innominate vein aneurysm presenting as an anterior mediastinal tumour in a young female." Vasa 47, no. 6 (2018): 515–17. http://dx.doi.org/10.1024/0301-1526/a000733.

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Abstract. We report a rare case of large innominate vein aneurysm in a young women clinically presenting with persistent dry cough and retrosternal pressure. Chest X-ray showed a mediastinal widening leading to thoracic computed tomography, MRI, and phlebography. Initial conservative treatment with regular follow-up was performed. Upon aneurysm growth and recurrent pulmonary infection we decided to surgically resect the aneurysm via a minimally invasive approach.

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42

Jochelson, M. S., N. J. Tarbell, and H. J. Weinstein. "Unusual thoracic radiographic findings in children treated for Hodgkin's disease." Journal of Clinical Oncology 4, no. 6 (1986): 874–82. http://dx.doi.org/10.1200/jco.1986.4.6.874.

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Mantle irradiation is often part of the treatment for Hodgkin's disease. Localized pneumonitis and fibrosis are well-known sequelae of this treatment. We report nine patients with unusual thoracic radiographic findings following treatment for Hodgkin's disease. All nine had mediastinal widening. Seven of these patients received combined modality therapy in which prednisone was given with their MOPP. In these seven patients, an increase in mediastinal width developed at the same time as the radiographic changes of radiation pneumonitis. Two patients developed bilateral infiltrates extending bey

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43

Dennis, LN, and LF Rogers. "Superior mediastinal widening from spine fractures mimicking aortic rupture on chest radiographs." American Journal of Roentgenology 152, no. 1 (1989): 27–30. http://dx.doi.org/10.2214/ajr.152.1.27.

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44

Heiberg, E. "Superior mediastinal widening from spine fractures mimicking aortic rupture on chest radiographs." American Journal of Roentgenology 152, no. 6 (1989): 1340. http://dx.doi.org/10.2214/ajr.152.6.1340-a.

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45

Burkill, G. J., P. R. Burn, and S. P. Padley. "Aneurysm of the left brachiocephalic vein: an unusual cause of mediastinal widening." British Journal of Radiology 70, no. 836 (1997): 837–39. http://dx.doi.org/10.1259/bjr.70.836.9486050.

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46

Davies, A. J., and D. E. Roberts. "Aneurysm of the left brachiocephalic vein: an unusual cause of mediastinal widening." British Journal of Radiology 71, no. 843 (1998): 347–48. http://dx.doi.org/10.1259/bjr.71.843.9616251.

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47

Miller, M. A., T. P. Coon, E. Miles, M. Belson, M. Patel, and J. Christensen. "The Impact of Pretest Probability upon Radiograph Interpretation: Anthrax and Mediastinal Widening." Annals of Emergency Medicine 46, no. 3 (2005): 70. http://dx.doi.org/10.1016/j.annemergmed.2005.06.261.

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48

Samal, Aditya K., Christopher J. White, and James B. Kot. "Penetrating Atherosclerotic Ulcer of the Aorta." Journal of Endovascular Therapy 8, no. 5 (2001): 534–38. http://dx.doi.org/10.1177/152660280100800517.

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Purpose: To describe a case of penetrating atherosclerotic ulcer of the aorta with a review of its natural history, diagnosis and management. Case Report: An elderly patient with a history of hypertension presented to the emergency room with the sudden onset of severe chest pain radiating to the back. The electrocardiogram showed left ventricular hypertrophy; the chest radiograph revealed mediastinal widening. Computed tomography was suspicious for a mediastinal hematoma without aortic dissection. Transesophageal echocardiography was also negative for dissection. An aortogram revealed a penetr

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49

Kumawat, Manoj Kumar, Neeti Sharma, Shankar Lal Jakhar, H. S. Kumar, and Rajesh Kumar. "A Review of Literature on Thymoma: An Indolent Tumor of Anterior Mediastimum." Asian Pacific Journal of Cancer Care 9, no. 2 (2024): 353–56. http://dx.doi.org/10.31557/apjcc.2024.9.2.353-356.

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Thymic tumours are a heterogeneous group of malignancies with a range of clinical presentations. The most common types are thymoma and thymic carcinoma, but overall it remains a rare cancer, and one without a clear aetiology. About 50% are diagnosed incidentlly with chest radiography. Thymoma is classified into different stages, which determine the prognosis and type of management. Different types of treatments are available for patients with thymoma. Thymectomy to remove the tumor is the most common treatment of thymoma. We present a case of 20 yr old male presented with shortness of breath,

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50

Joseph, Thomas Jeo, Barney Thomas Isaac, Prince James, and Balamugesh Thangakunam. "Reversible platypnoea-orthodeoxia syndrome." BMJ Case Reports 16, no. 10 (2023): e255587. http://dx.doi.org/10.1136/bcr-2023-255587.

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Platypnoea-orthodeoxia syndrome is characterised by dyspnoea and oxygen desaturation in the upright position usually caused by an extracardiac shunt and less often due to dynamic factors that accentuate an intracardiac right-to-left shunt. In our patient, the collapse of lower lobe of left lung secondary to bronchial stenosis due to endobronchial tuberculosis and resultant mediastinal shift was the factor that led to an otherwise unrecognised intracardiac right-to-left shunt leading to platypnoea-orthodeoxia. We postulate that there would have been an increased stretching and widening of a pat

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