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Books on the topic 'Mediated activity'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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1

Ravetch, Jeffrey V., and Falk Nimmerjahn, eds. Fc Mediated Activity of Antibodies. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-31053-0.

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2

Leiman, Mikael. Integrating the Vygotskian theory of sign-mediated activity and the British object relations theory. Joensuun yliopisto, 1994.

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3

Integrating the Vygotskian theory of sign-mediated activity and the British object relations theory. Joensuun yliopisto, 1994.

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4

Leaper, Lyn. An investigation of phytochrome-mediated control of ascorbate oxidase activity in Mustard cotyledons (Sinapis alba L.). University of Birmingham, 1987.

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5

Kay, Lyndsey Sara. Anti-B-cell lymphoma activity mediated by CD3+CD4-CD8- T cells activated in vitro or in vivo. National Library of Canada, 2003.

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6

Myllynen, Jenni Eileen. The effect of nerve-mediated activity on the expression of Muscle Regulatory Factor and Myosin Heavy Chain Protein mRNA transcripts. Laurentian University, Behavioural Neuroscience Program, 1997.

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7

Angstzonen: Rechtsdominierte Orte aus medialer und lokaler Perspektive. VS, Verl. fu r Sozialwiss., 2008.

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8

Gerster, Anita E. Calonder. La situation de la femme active: Causes mediates et immediates des problemes particuliers que rencontrent les femmes dans le choix de leur profession, dans leur carriere et lorsqu'elles interrompent ou reprennent leur activité professionnelle. OFIAMT, 1990.

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9

Nimmerjahn, Falk, and Jeffrey V. Ravetch. Fc Mediated Activity of Antibodies: Structural and Functional Diversity. Springer, 2019.

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10

Pun, Joyce Man-Yin. Characterizing anti-tumor activity mediated by double negative T cells. 2006.

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11

Beninger, Richard J. Mechanisms of dopamine-mediated incentive learning. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198824091.003.0012.

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Mechanisms of dopamine-mediated incentive learning explains how sensory events, resulting from an animal’s movement and the environment, activate cortical glutamatergic projections to dendritic spines of striatal medium spiny neurons to initiate a wave of phosphorylation. If no rewarding stimulus is encountered, a subsequent wave of phosphatase activity undoes the phosphorylation. If a rewarding stimulus is encountered, dopamine initiates a cascade of events in D1 receptor-expressing medium spiny neurons that may prevent the phosphatase effects and work synergistically with signaling events pr

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12

Coyle, Patricia K. Immune-mediated Disorders of the Central Nervous System. Edited by Emma Ciafaloni, Cheryl Bushnell, and Loralei L. Thornburg. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190667351.003.0010.

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This chapter reviews pregnancy in multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and acute transverse myelitis (ATM) syndrome. MS is a major acquired disease of young adults, with a rising female predominance. MS has no direct negative consequences on fertility or pregnancy. Pregnancy has a profound effect on MS, with decrease in disease activity during the last trimester counteracted by a three-month postpartum increase in disease activity. With the development of disease-modifying therapies, important questions arise about washout periods, the feasibility and risks

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13

Kalitsky-Szirtes, Juliana. Impact of inflamation-mediated changes in expression and activity of PGP and CYP3A on drug disposition. 2003.

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14

Fedosov, Anton. Supporting the Design of Technology-Mediated Sharing Practices. Carl Grossmann, 2020. http://dx.doi.org/10.24921/2020.94115943.

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Online social networks have made sharing personal experiences with others mostly in form of photos and comments a common activity. The convergenceof social, mobile, cloud and wearable computing expanded the scope of usergeneratedand shared content on the net from personal media to individual preferencesto physiological details (e.g., in the form of daily workouts) to informationabout real-world possessions (e.g., apartments, cars). Once everydaythings become increasingly networked (i.e., the Internet of Things), future onlineservices and connected devices will only expand the set of things to

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15

Klein, Amanda H., and Matthias Ringkamp. Peripheral neural mechanisms of cutaneous heat hyperalgesia and heat pain. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0024.

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In the landmark paper discussed in this chapter, published in 1982, LaMotte et al. investigated the contribution of different cutaneous nerve fibres to heat pain and heat hyperalgesia in both psychophysical (humans) and electrophysiological studies (human and primates), using identical thermal test and conditioning stimuli; the findings from the two sets of experiments were then correlated. In non-human primates, neuronal activity was recorded from mechanoheat-sensitive A- and C-fibres (AMHs and CMHs, respectively) and warm and cold fibres, whereas, in conscious human volunteers, activity from

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16

Celebrity Philanthropy and Activism: Mediated Interventions in the Global Public Sphere. Routledge, 2018.

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17

Medjeral-Thomas, Nicholas, Anna Richards, and Matthew C. Pickering. Molecular basis of complement-mediated renal disease. Edited by Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0333.

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Abnormal regulation of complement is intimately associated with C3 glomerulopathy and atypical haemolytic uraemic syndrome. Atypical haemolytic uraemic syndrome is characterized by renal thrombotic microangiopathy due to an inability to regulate complement activation along the renal endothelium. The development of thrombosis is critically dependent on the ability to activate C5. Eculizumab, a monoclonal anti-C5 antibody, is an effective therapy for this condition. C3 glomerulopathy refers to glomerular lesions characterized by accumulation of C3 in the absence of immunoglobulin. The prototypic

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18

Harrington, Lesley, and Benjamin Osipov. The Developing Forager. Edited by Sally Crawford, Dawn M. Hadley, and Gillian Shepherd. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780199670697.013.23.

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Studies of regional and chronological variation in skeletal markers of physical activity in past hunter-gatherer populations typically focus on adults, however, patterns of bone strength develop predominantly during childhood and adolescence. Ethnographic studies suggest that differences in environment and subsistence strategy would have brought about variation in how children grew up to be productive foragers capable of procuring food for themselves and others. Different foraging activities require varying degrees of physical strength and skills development. These factors would have influence

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19

Mechanism of action of TENS. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199673278.003.0009.

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There has been an abundance of research using animal, healthy human, and patients on the mechanism of action of TENS. Activity in peripheral nerves generated during TENS will influence physiological actions at peripheral, spinal, and supraspinal sites of the nervous system. Some of these physiological actions are mediated by alterations in the concentrations of neurochemicals dependent on the electrical characteristics of TENS. The purpose of this chapter is to discuss research evidence that has contributed to our knowledge about the physiological and pharmacological actions of TENS, including

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20

Impett, Jonathan. Making a mark The psychology of composition. Edited by Susan Hallam, Ian Cross, and Michael Thaut. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780199298457.013.0037.

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This article discusses the psychology of composition. Composition is a reflexive, iterative process of inscription. The work, once named as such and externalizable to some degree, passes circularly between inner and outer states. It passes through internal and external representations – mostly partial or compressed, some projected in mental rather than physical space, not all necessarily conscious or observable – and phenomenological experience, real or imagined. At each state-change the work is re-mediated by the composer, whose decision-making process is conditioned by the full complexity of

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21

Frenkel, Joost, and Hans R. Waterham. Mevalonate Kinase Deficiency. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0039.

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Mevalonate kinase deficiency (MKD) is an autosomal recessive inborn error of isoprenoid biosynthesis, a pathway yielding sterols and nonsterol isoprenoids.In patients, the enzyme activity of mevalonate kinase is severely reduced due to mutations in the encoding gene, MVK. The substrate, mevalonate, accumulates and is elevated in blood and urine. Shortage of certain downstream products of the pathway, nonsterol isoprenoids, leads to dysregulation of the innate immune system, activation of inflammasomes, and interleukin (IL)-1 mediated inflammation.Symptoms start in early childhood with recurren

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22

Colombetti, Giovanna, and Neil Harrison. From physiology to experience: Enriching existing conceptions of “arousal” in affective science. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198811930.003.0013.

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This chapter examines the notion of “arousal”, an influential notion in affective science referring to the degree of an individual’s “activation” or “excitement” during an emotional state. It considers this notion specifically in relation to interoception, defined broadly as “sensitivity to stimuli arising inside the organism.” “Physiological arousal” is distinguished from “experienced arousal” and it is argued that both need to be characterized more broadly than commonly done. Physiological arousal cannot be reduced to sympathetic activation, as it involves complex interactions between multip

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23

Mari, Manuela. Powers in Dialogue. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198804208.003.0005.

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Building on a slate of recent discoveries and publications, the chapter investigates how the Macedonian kings employed letters and so-called diagrammata to interact with and to rule over cities within their reign and regions under their control. It thus brings to life the diplomatic activity between court and constituencies that defined the political culture of fourth-century BCE Macedonia: the different types of missives used by the kings yield important insights into the administrative hierarchies and institutional procedures (as well as the ‘styles’ of exercising power) that sustained royal

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24

Beninger, Richard J. Introduction. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198824091.003.0001.

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The Introduction provides a brief overview of the book. The central theme is dopamine-mediated reward-related incentive learning—the acquisition by neutral stimuli of an increased ability to elicit approach and other responses. The brain has multiple memory systems defined as “declarative” and “non-declarative”; incentive learning produces one form of non-declarative memory. Once incentive learning is established it is gradually lost when the rewarding stimulus is no longer available or when dopamine function is reduced. Decreases in dopaminergic neurotransmission may produce inverse incentive

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25

Crous-Bou, Marta, Immaculata de Vivo, and Pagona Lagiou. Endometrial Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190676827.003.0018.

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Lifestyle factors contribute appreciably to endometrial cancer risk, with obesity accounting for over one-third of incident cases in high-income societies. Unlike cervical cancer, which is a model of viral carcinogenesis, endometrial cancer is considered a model of hormonal carcinogenesis, as use of unopposed estrogens postmenopausally and obesity are the best-established risk factors. Endometrial cancer is also the only known malignancy for which cigarette smoking has been shown to confer protection. Risk reduction conferred by current smoking, past oral contraceptive use, childbearing, and p

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26

Lorino, Philippe. Inquiry. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198753216.003.0004.

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This chapter narrates the efforts of a hospital cardiology department to create its country’s first chronic heart failure (CHF) multidisciplinary unit. With an average treatment cost that was too high, threatening their required funding, the department’s actors strove to reduce it. They analyzed collective activity, made exploratory hypotheses about cost drivers, and developed new performance measurements to verify their hypotheses. This is an example of the social process of inquiry. The chapter presents the pragmatist definition of inquiry, a non-dualist and relational framework, recursively

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27

Buetefisch, Cathrin M., and Leonardo G. Cohen. Use-dependent changes in TMS measures. Edited by Charles M. Epstein, Eric M. Wassermann, and Ulf Ziemann. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780198568926.013.0018.

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Adult brains maintain the ability to reorganize throughout life. Cortical reorganization or plasticity includes modification of synaptic efficacy as well as neuronal networks that carry behavioural implications. Transcranial magnetic stimulation (TMS) allows for the study of primary motor cortex reorganization in humans. Motor-evoked potential (MEP) amplitudes change in response to practice. This article gives information about the effect of practice on TMS measures such as motor-evoked potential amplitudes, motor maps, paired-pulse measures, and behavioural measures. These changes may be acco

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28

Herman, James P. Limbic Pathways to Stress Control. Edited by Israel Liberzon and Kerry J. Ressler. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190215422.003.0008.

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Appropriate control of the HPA (hypothalamo-pituitary-adrenocortical axis) is required for adaptation to physiological and environmental challenges. Inadequate control is linked to numerous stress-related pathologies, including PTSD, highlighting its importance in linking physiological stress responses with behavioral coping strategies. This chapter highlights neurocircuit mechanisms underlying HPA axis adaptation and pathology. Control of the HPA stress response is mediated by the coordinated activity of numerous limbic brain regions, including the prefrontal cortex, hippocampus, and amygdala

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29

Mediated Communities: Civic Voices, Empowerment and Media Literacy in the Digital Era. Lang AG International Academic Publishers, Peter, 2014.

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30

Shumow, Moses. Mediated Communities: Civic Voices, Empowerment and Media Literacy in the Digital ERA. Lang Publishing, Incorporated, Peter, 2014.

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31

Spector, Regine A. Order at the Bazaar. Cornell University Press, 2018. http://dx.doi.org/10.7591/cornell/9781501709326.001.0001.

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Over the past two decades, bazaars mushroomed in the new Central Asian states, where rule-of-law institutions are weak and corruption high. How did bazaars grow and thrive in such an inhospitable context? Order at the Bazaar answers this question through an analysis of bazaars in Kyrgyzstan. They are conceptualized as islands of order within a chaotic national context. The findings demonstrate that those at the bazaar, including traders, private land owners, and municipal officials, create order themselves in the absence of a coherent national government apparatus and bureaucratic state. Drawi

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32

Ralston, Stuart H. Paget’s disease of bone. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199642489.003.0144_update_001.

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Paget’s disease of bone (PDB) affects up to 1% of people of European origin aged 55 years and above. It is characterized by focal abnormalities of bone remodelling which disrupt normal bone architecture, leading to expansion and reduced mechanical strength of affected bones. This can lead to various complications including deformity, fracture, nerve compression syndromes, and osteoarthritis, although many patients are asymptomatic. Genetic factors play a key role in the pathogenesis of PDB. This seems to be mediated by a combination of rare genetic variants which cause familial forms of the di

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Ralston, Stuart H. Paget’s disease of bone. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0144.

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Paget's disease of bone (PDB) affects up to 1% of people of European origin aged 55 years and above. It is characterized by focal abnormalities of bone remodelling which disrupt normal bone architecture, leading to expansion and reduced mechanical strength of affected bones. This can lead to various complications including deformity, fracture, nerve compression syndromes, and osteoarthritis, although many patients are asymptomatic. Genetic factors play a key role in the pathogenesis of PDB. This seems to be mediated by a combination of rare genetic variants which cause familial forms of the di

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34

Kirchman, David L. Introduction to geomicrobiology. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198789406.003.0013.

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Geomicrobiology, the marriage of geology and microbiology, is about the impact of microbes on Earth materials in terrestrial systems and sediments. Many geomicrobiological processes occur over long timescales. Even the slow growth and low activity of microbes, however, have big effects when added up over millennia. After reviewing the basics of bacteria–surface interactions, the chapter moves on to discussing biomineralization, which is the microbially mediated formation of solid minerals from soluble ions. The role of microbes can vary from merely providing passive surfaces for mineral format

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35

Tenhunen, Sirpa. Mediating Conflict. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190630270.003.0006.

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Chapter 6 provides an overview of the studies on new media’s role for political activism and then examines how mobile phones mediate political action by exploring activists’ use of mobile phones for their daily political work in rural West Bengal. The ethnographic fieldwork was carried out during the rise of the opposition, the Trinamul Congress Party, in West Bengal; consequently, the chapter also highlights the factors that helped bring the Trinamul Congress Party to power after decades of the Left Front Government’s rule of the state. This chapter illustrates how phone use builds on earlier

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36

Han, Shihui. Cultural differences in neurocognitive processing of the self. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780198743194.003.0004.

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Chapter 4 examines the difference in self-concept proposed by philosophers and psychologists in Western and East Asian cultures. It then introduces a dominant theoretical framework of cultural differences in self-concept that focuses on independence and interdependence in Western and East Asian cultures, respectively. It reviews behavioral and brain imaging findings that reveal cognitive and neural mechanisms underlying self-advantage during face recognition. It also examines the neural mechanisms related to self-reflection in Western and East Asian cultures by showing that the enhanced activi

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37

Millie, Julian. The Listening Audience Laughs and Cries, the Writing Public Thinks. Cornell University Press, 2018. http://dx.doi.org/10.7591/cornell/9781501713118.003.0006.

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The second part of the book commences with Chapter Six. It analyses the connections Indonesian Muslims make between preaching styles and subjectivities, and the norms of citizen subjectivity that shape these connections. Chapter Six explores a progressive critique of preaching routines, describing a competition in which contestants write about the Qur’an. This was specifically conceived by a Bandung activist concerned about the negative effects of listening on Indonesia’s democratic future. Rationales for the project reveal authoritative conceptions of how Islam should properly be mediated.

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38

Penney, Joel. The Citizen Marketer. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780190658052.001.0001.

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From hashtag activism to the flood of political memes on social media, the landscape of political communication is being transformed by the grassroots circulation of opinion on digital platforms and beyond. The Citizen Marketer offers a new framework for understanding this phenomenon by exploring how everyday people assist in the promotion of political media messages in hopes of persuading their peers and shaping the public mind. The analysis is grounded in the firsthand testimony of citizens who have engaged in popular activities such as changing their profile picture to a protest symbol, twe

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39

Mease, Philip. Biologic treatments for psoriatic arthritis apart from TNF inhibition. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198737582.003.0030.

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Psoriatic arthritis (PsA) is an immunologically mediated inflammatory disease characterized by arthritis, enthesitis, dactylitis, spondylitis, and psoriasis. Prior to the introduction of targeted biologic medications, such as TNF inhibitors, the ability to control disease activity was limited, with only modest effects noted with traditional oral medications such as methotrexate and sulfasalazine. The introduction of TNF inhibitors substantially changed the outlook of PsA patients, yielding significant response in all relevant clinical domains and demonstrating the ability to inhibit progressiv

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40

Günther, Christoph, and Simone Pfeifer, eds. Jihadi Audiovisuality and its Entanglements. Edinburgh University Press, 2020. http://dx.doi.org/10.3366/edinburgh/9781474467513.001.0001.

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This volume situates jihadi audio-visual media within a global communicative web, and provides perspectives that relate the production and dissemination of jihadi images and sound to various forms of engagement and appropriation. Through 12 case studies, this book examines the different ways in which Jihadi groups and their supporters use visualisation, sound production and aesthetic means to articulate their cause in online as well as offline contexts and how different actors relate to these media. Divided into four thematic sections, the chapters probe Jihadi appropriation of traditional and

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41

Taylor, Sarah McFarland. Ecopiety. NYU Press, 2019. http://dx.doi.org/10.18574/nyu/9781479810765.001.0001.

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This bookanalyzes diverse representations of environmental moral engagement in contemporary mediated popular culture. It identifies and explores intertwining, co-constitutive, yet contrary stories of what the author terms “ecopiety” and “consumopiety” as they flow across multiple media platforms. The way these stories compete and conflict, vying for space as contested narratives in the public imagination, constitutes a central inquiry of the book. Drawing together theoretical insights from cultural studies, media studies, environmental humanities, and religious studies, the book offers a criti

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42

Emerich, Monica M. Neither Mainstream nor Alternative. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252036422.003.0002.

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This chapter examines LOHAS as a bridge between the two poles of the American marketplace—the “alternative” market and the “mainstream” or conventional market. This market-based binary shaped and informed many of the industries now considered part of the domain of LOHAS. These companies and industries once purposefully positioned themselves as alternative. “Alternative” defined their intended consumer base, their company missions, and even, in many cases, the founder's personal values. Today, however, LOHAS organizations regard this alterity as more of a handicap than an advantage. Moreover, t

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43

Martínez-François, Juan Ramón, Nika N. Danial, and Gary Yellen. Metabolic Seizure Resistance via BAD and KATP Channels. Edited by Detlev Boison. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0028.

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On a ketogenic diet, ketone bodies provide an alternative fuel, replacing much of the glucose used ordinarily by the brain. This switch is thought to underlie its anticonvulsant effects. Brain fuel utilization can also be modified by a nondietary approach: genetic alteration of the protein BAD, which has known roles in regulating both apoptosis and glucose metabolism. When the metabolic function of BAD is genetically altered in mice, it produces reduced glucose and increased ketone body metabolism in neurons and astrocytes. This effect is related to regulation of BAD by phosphorylation and is

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44

Cayari, Christopher. Music Making on YouTube. Edited by Roger Mantie and Gareth Dylan Smith. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780190244705.013.15.

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People are making music at their leisure and publishing it online. YouTube has provided a space for musicians to publish multitrack music videos, join collective musical ensembles, and collaboratively perform with others. This chapter explores three trends of how musicians are creating music videos and forming virtual ensembles and music making communities: they are showing off their skills through music videos; they are creating videos to join large collective multitrack ensembles of hundreds or even thousands of others; and they are actively collaborating with small groups to create mediated

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Miller, John F., and Jenny Strauss Clay, eds. Tracking Hermes, Pursuing Mercury. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198777342.001.0001.

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Of all the divinities of classical antiquity, the Greek Hermes (= Roman Mercury) is the most versatile, enigmatic, complex, and ambiguous. The runt of the Olympian litter, he is the god of lies and tricks, yet also kindly to mankind and bringer of luck; his functions embrace both the marking of boundaries and their transgression, commerce, lucre, and theft, rhetoric, and practical jokes; he also plays the role of mediator between all realms of human and divine activity, embracing heaven, earth, and the Netherworld. The twenty original contributions in this volume bring together a wide range of

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46

Burton, Derek, and Margaret Burton. Integration and control: the nervous system. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198785552.003.0011.

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The complexity of fish behaviour and information processing indicates high levels of neural, anatomical and functional organization. Neural cells are conducting neurons and neuroglia with putative support and physiological roles. Neuronal conduction, synaptic transmission, reflexes and neuropils are factors in integrative activity and information processing. Fish nervous systems are organized into central (brain and spinal cord) and peripheral (including autonomic) components. Interestingly the structure and function of the fish optic tectum have been considered comparable to those of the tetr

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47

Schneier, Franklin R., Hilary B. Vidair, Leslie R. Vogel, and Philip R. Muskin. Anxiety, Obsessive-Compulsive, and Stress Disorders. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199326075.003.0006.

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Patients with generalized anxiety disorder experience anxiety related to multiple areas, such as work, finances, and illness. Discrete, unexpected panic attacks and anticipatory anxiety characterize patients with panic disorder. Patients with social anxiety disorder have fear of embarrassment in social situations. Patients with obsessive-compulsive disorder are preoccupied with and distressed by inappropriate thoughts, urges, and images. The four cardinal features of posttraumatic stress disorder are intrusive reexperiencing of the initial trauma, avoidance, persistent negative alterations in

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48

Price, Chane, Zahid Huq, Eellan Sivanesan, and Constantine Sarantopoulos. Pain Pathways and Pain Physiology. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190457006.003.0001.

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Pain is a multidimensional sensory experience that is mediated by complex peripheral and central neuroanatomical pathways and mechanisms. Typically, noxious stimuli activate specific peripheral nerve terminals onto Aδ‎ and C nerve fibers that convey pain and generate signals that are relayed and processed in the spinal cord and then conveyed via the spinothalamic tracts to the contralateral thalamus and from there to the brain. Acute pain is self-limited and resolves with the healing process, but conditions of extensive injury or inflammation sensitize the pain pathways and generate aberrant,

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49

Thompson, Douglas I. Radical Moderation. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190679934.003.0006.

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Renaissance theories of diplomacy seek to address the tension between the ambassador’s dual roles as mediator between princes and representative of one prince exclusively. Michel de Montaigne transposes this concern onto the question of how to negotiate the resolution of civil conflict when one is a partisan within the conflict. In his view, moderation is the capacity that this activity demands. This is a deeply paradoxical virtue: if one is to be moderate and not overly hostile toward all signs of partisanship, one must retain some contact with partisan extremes. Montaigne argues that one sho

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50

Penney, Joel. Self-Labeled and Visible Identities. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780190658052.003.0003.

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This chapter focuses on the identity politics of social movements and uses the case study of gay and lesbian activism to examine how citizen media participation is mobilized in strategic projects of public visibility. It charts how citizens use mediated acts of self-labeling, such as changing profile pictures on social media, to announce the presence of their identities and attempt to influence perceptions of social and political reality. This model of “coming out” may have particular resonance for the LGBT community that has long sought to end its historical invisibility, yet it has also been

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