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Journal articles on the topic 'Medicinal ointment'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Maribjanovna, Kakharova Dildora, Khoshimova Dilrabo Khoshimovna, Nazarov Bakhtiyor Mamajonovich, and Madaminkhudzhaeva Dilafruz Kakhramonjon Qizi. "THE USE OF ANTIBACTERIAL EYE OINTMENTS IN THE TREATMENT OF ACUTE AND CHRONIC DISEASES OF THE EYELIDS AND CONJUNCTIVA." American Journal of Medical Sciences and Pharmaceutical Research 05, no. 05 (2023): 18–19. http://dx.doi.org/10.37547/tajmspr/volume05issue05-05.

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Currently, many studies are being carried out to study the effectiveness of ointment ophthalmic preparations. Ophthalmic ointments are unique in that they have a multicomponent mechanism of action. On the one hand, due to the ointment base, the effect of the medicinal substance itself is prolonged, and on the other hand, due to the structural features of the mucous membrane of the conjunctival cavity, these medicinal substances are very quickly absorbed. In the treatment of pathology of the ocular surface, including meibomyitis, barley and chalazion, preference is given to local therapy and oi

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2

Mona, Madake, and Pawar Pratiksha. "Formulation and Evaluation of Antifungal Ointment from Galinsoga Parviflora." International Journal of Multidisciplinary Research Transactions 6, no. 4 (2024): 95–124. https://doi.org/10.5281/zenodo.10969013.

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Antifungal ointments have gained significant attention as natural alternative for treating various skin conditions due to their potential therapeutic benefits and minimal side effects . This study aimed to formulate and evaluate a herbal ointment with a focus on its anti – fungal properties. The ointment was formulated using accombination of medicinal herbs known for their anti-fungal effects , with Galinsoga parviflora as the primary active ingredients . The formulation process involved extraction of the bioactive compounds from Galinsoga parviflora and incorporation into a suitable oin

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3

Kaushal, Dev, and Nikita Upadhyaya. "REVIEW ON OINTMENT." International Journal of Pharmaceutical Sciences and Medicine 7, no. 10 (2022): 30–38. http://dx.doi.org/10.47760/ijpsm.2022.v07i10.003.

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Ointments are semisolid dosage form which usually act as visco-elastic materials when shear stress is applied. They generally contain medicinal ingredients and are used to be applied externally to the body for therapeutic effect. Many therapeutic agents used for topical application to intact or broken skin or to mucous membranes are presented in the form of semisolid consistency variously designated as ointments, creams, pastes etc. It is used mainly as protective or emollient for the skin. The first step towards the goal is screening of plants used in popular medicine. Along with other dosage

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4

Butko, Yaroslava, Oksana Tkachova, Tetyana Tishakova, Anatoly Gordienko та Yevhen Bondariev. "Wound healing effect of “Prolidoxid” and “Dexpanthenol with ceramides”: a сomparative study based on the model of chemical burns with expressed alterative skin processes". ScienceRise: Pharmaceutical Science, № 2 (30) (30 квітня 2021): 26–32. http://dx.doi.org/10.15587/2519-4852.2021.230031.

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Pharmacotherapy of chemical skin injuries remains an urgent issue today due to its serious health consequences and possible development of complications. Topical treatment is one of the most effective methods of wound treatment using hydrophilic ointments and creams. For now, range of hydrophilic medicinal products with a broad spectrum of action is limited. That is why a search and development of new hydrophilic ointments and creams remains an urgent challenge. The aim. The aim of this research was to study effectiveness of ointment “Prolidoxid” and cream “Dexpanthenol with ceramides” o

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5

Renuka, Sutane* Dr. Pavan Folane Dr. K. R. Biyani. "Formulation & Evaluation of Antifungal Activity of Polyherbal Ointment in Animal Model." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 2834–39. https://doi.org/10.5281/zenodo.15449114.

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Polyherbal ointments are topical preparations that combine multiple medicinal herbs for enhanced therapeutic action. They target specific conditions like wound healing, pain relief, or skin care. Common types include wound healing ointments containing herbs like aloe vera, calendula, and turmeric, known for their antimicrobial and anti-inflammatory properties. Pain relief ointments use herbs like arnica, ginger, and eucalyptus, providing analgesic and anti-inflammatory effects. Skin care ointments may include neem, lavender, and chamomile, which can soothe and nourish the skin, potentially hel

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Demilew, Wubante, Getnet Mequanint Adinew, and Seyfe Asrade. "Evaluation of the Wound Healing Activity of the Crude Extract of Leaves of Acanthus polystachyus Delile (Acanthaceae)." Evidence-Based Complementary and Alternative Medicine 2018 (June 11, 2018): 1–9. http://dx.doi.org/10.1155/2018/2047896.

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Background. Medicinal plants play indispensable roles to treat various ailments. Acanthus polystachyus is one of the medicinal plants used traditionally for treatment of wounds. However, there were no scientific reports documented so far on the wound healing activities of this plant. Thus, the present study provides a scientific evaluation for the wound healing potential of the crude extract of A. polystachyus leaves. Methods. The crude extraction was carried out using 80% methanol. The crude extract was prepared in 5% (w/w) and 10% (w/w) ointment and evaluated for wound healing activity using

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7

Moniruzzaman, M., and MR Gofur. "Effects of Dad Mardan (Cassia alata) and Ata leaves (Annona reticulata ) against skin diseases of calves." Bangladesh Journal of Livestock Research 20, no. 1-2 (2020): 112–18. http://dx.doi.org/10.3329/bjlr.v20i1-2.47025.

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A number of indigenous plants actively used for therapeutic purpose in Bangladesh. The research work was conducted to investigate the effects of indigenous medicinal plants, Dad Mardan (Cassia alata) and Ata (Annona reticulata) against skin diseases (ringworm, scabies, dermatitis, wounds) in calves. The protective efficacy was observed by the topical application of the 10% combined ointment (Dad Mardan and Ata leaves) and 20% Dad Mardan ointment twice daily on nine calves having skin lesions. Calves treated with combined ointment were almost cured at 21st day of post-treatment whereas calves t

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8

Yaroslava, Butko, Tkachova Oksana, Tishakova Tetyana, Gordienko Anatoly та Bondariev Yevhen. "Wound healing effect of "Prolidoxid" and "Dexpanthenol with ceramides": a сomparative study based on the model of chemical burns with expressed alterative skin processes". ScienceRise: Pharmaceutical Science, № 2(30) (30 квітня 2021): 26–32. https://doi.org/10.15587/2519-4852.2021.230031.

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Pharmacotherapy of chemical skin injuries remains an urgent issue today due to its serious health consequences and possible development of complications. Topical treatment is one of the most effective methods of wound treatment using hydrophilic ointments and creams. For now, range of hydrophilic medicinal products with a broad spectrum of action is limited. That is why a search and development of new hydrophilic ointments and creams remains an urgent challenge. <strong>The aim.</strong> The aim of this research was to study effectiveness of ointment “Prolidoxid” and cream &ld

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9

Nasirah Maulidia Ajhar, Effendy De Lux Putra, and Emil Salim. "Formulation of ointment from extract and fractions of Castanopsis costata leaves." World Journal of Advanced Research and Reviews 17, no. 1 (2023): 230–35. http://dx.doi.org/10.30574/wjarr.2023.17.1.0028.

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Background: Castanopsis costata (Blume) A. DC. or commonly known as cep-cepan is a medicinal plant widely used based on experience by Karo people in Indonesia n the Karo community for the treatment of wounds. However, no research has been done to prove this experience. Initially, the formulation of ointment extract and leaf fractions of C. costata need to be carried out. Aim: The purpose of this study was to provide information about the chemical group content contained in C. costata leaf extract and fractions and to evaluate their ointment preparation according to the requirements of ointment

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10

Nurhaningrum, Selvy Adita, Umi Nafisah, and Ester Dwi Antari. "FORMULASI DAN UJI FISIK SEDIAAN SALEP EKSTRAK DAUN KERSEN (Muntingia calabura L.) DENGAN VARIASI KONSENTRASI BASIS PEG 400 DAN PEG 4000." Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat 5, no. 1 (2021): 33–37. http://dx.doi.org/10.46808/farmasindo.v5i1.53.

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Cherry leaves (Muntingia calabura L.) is a medicinal plant that is rarely used by the public. Its use is still traditional so it needs to be made in more practical preparations eg ointments. The purpose of this study was to determine the ethanol extract form of cherry leaves in ointment preparations and make ointment preparations containing ethanol extract of cherry leaves. In this study using an experimental analytical method by making ointment preparations using an ointment base. The basic ointment used is a combination of PEG 400 and PEG 4000, so that 3 formulations obtained with a concentr

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11

Trubilin, V. N., E. G. Poluninа, D. V. Andzhelova, V. V. Kurenkov, Yu V. Evstigneeva, and K. V. Chinenova. "The Antibacterial Eye Ointments in the Treatment of Eyelids and Conjunctiva Acute and Chronic Diseases." Ophthalmology in Russia 16, no. 1 (2019): 31–37. http://dx.doi.org/10.18008/1816-5095-2019-1-31-37.

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Currently, there are many studies on the effectiveness of ointment ophthalmological medicines. Ophthalmic ointments are unique because they have a multi-component action mechanism. On the one hand, the action of the medicinal substance itself is prolonged due to the ointment base, and on the other hand, due to the structural features of the conjunctival cavity mucosa, these medicinal substances are very rapidly absorbed. In the treatment of ocular surface pathology, including as meibomiitis, barley and chalazions, local therapy and ointment forms are preferred. The purpose of the study was the

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12

Katsaraba, O. A., R. M. Sachuk, B. V. Gutyj, et al. "Pharmacological studies of the veterinary medicinal product “Dibutalastin Ointment”." Ukrainian Journal of Veterinary and Agricultural Sciences 5, no. 2 (2022): 43–48. http://dx.doi.org/10.32718/ujvas5-2.07.

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The study of pharmacological studies of the veterinary medicinal product for external use in the form of ointment – “Dibutalastin Ointment” is a mandatory stage of preclinical research of the drug, which is a new development of PP “Biopharm” and LLC “DEVIE”. In a scientific experiment on laboratory animals, it is possible to assess the drug's safety for different terms of use to determine the zone of toxic action and doses that do not cause harmful effects on health. Therefore, the work aimed to carry out pharmacological studies of the drug with methyl salicylate and dimethyl sulfoxide in the

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13

Shukla, Rashmi, and Varsha Kashaw. "Development, characterization and evaluation of herbal ointment containing momordica charantia, pongamia glabra and piper nigrum." Journal of Drug Delivery and Therapeutics 9, no. 1 (2019): 136–40. http://dx.doi.org/10.22270/jddt.v9i1.2190.

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Objective: The objective of present study was the development, characterization and evaluation of poly-herbal ointment formulation of pongamia glabra, piper nigrum and momordica charantia extract. Plant derived substances and herbal medicines have recently attracted the great interest towards their versatile application. Medicinal plants are the richest source of bioactive compounds used in traditional and modern medicine. The ointment formulation of plant extract has a sound approach to develop a poly-herbal ointment. The poly-herbal ointment formulation was evaluated for its physicochemical

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14

Rekha, Kandukuri* Dr. Shalini Kapoor Mehta Pavithra Amarnath Reddy A. "Crafting and Advancements of Pippali and Cissus Quadrangularis Anti- Inflammatory & Anti-Rheumatic Herbal Ointment." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 864–76. https://doi.org/10.5281/zenodo.15005488.

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Crafting and Advancements of Pippali and Cissus Quadrangularis Anti-Inflammatory & Anti-Rheumatic Herbal Ointment” Are Viscous semi-solid formulations called ointments are applied externally to the skin or mucous membranes. Using two traditional medicinal herbs, Cissus quadrangularis and pippali (long pepper), the study's objective was to create and assess an herbal ointment having anti- inflammatory and anti-rheumatic qualities. A fusion technique and trituration were used for the preparation. Throughout the development phase, three distinct formulations were used: Placebo: This for

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15

Hasanah, Iim. "the formulation of the basil (Ocimum Basilicum Linn) leaf juiced ointment as a liniment." JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 5, no. 1 (2022): 9–14. http://dx.doi.org/10.53864/jifakfar.v5i1.67.

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Basil is traditional medicinal plants found a lot of in Indonesia. Basil leaves affication as analgetic, antiinflamantory, bacteria and antioxidant. This study aims to make an ointment stock that fulfills the requirements of preparation, knowing the physical properties of basil (Ocimum sanctum L) leaf juice. This research is an experimental research by making and evaluating basil leaves ointment preparations. The result of this research is that the juice of basil leaves (Ocimum sanctum L) containing the flavanoid compounds, tannins, and steroids and can be made as ointment stock that fulfill t

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16

Kondratiuk, A. S. "COMPREHENSIVE REVIEW OF OINTMENT BASES: TYPES, PROPERTIES, AND APPLICATIONS." Biotechnologia Acta 18, no. 1 (2025): 5–15. https://doi.org/10.15407/biotech18.01.005.

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Aim. This article aims to comprehensively review and analyze various types of ointment bases, examining their physicochemical properties, advantages, and disadvantages. This review also seeks to explore the potential use of specific excipients in developing ointment bases with enhanced therapeutic properties and increased bioavailability of active pharmaceutical ingredients. Methods. A broad search and study of existing literature on ointment bases, focusing on their classifications, properties, and applications. A comparative analysis of the two main classifications of ointment bases based on

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17

Stavsky, Е. А., T. V. Teplyakova, А. P. Nadeev, et al. "COMPARATIVE EVALUATION OF THE WOUND-HEALING ACTIVITY OF OINTMENTS OBTAINED ON THE BASIS OF SOME BIOLOGICALLY ACTIVE COMPLEXES FROM HIGHER BASIDIOMYCETES." Sibirskij medicinskij vestnik 6, no. 3 (2022): 62–73. http://dx.doi.org/10.31549/2541-8289-2022-6-3-62-73.

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Introduction. In connection with the acquisition of antibiotic resistance of pyogenic microbiota, the problem of topical (drug) treatment of wounds has become aggravated. Aim. Comparative in vivo evaluation of the medicinal properties of ointments prepared on the basis of some biologically active complexes from higher basidiomycetes. Materials and methods. Experimental ointments were obtained on the basis of melanins from the natural raw materials of the сhaga Inonotus obliquus and from its deep-liquid culture, total polysaccharides from the oyster mushroom Pleurotus ostreatus, as well as the

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18

Samala, Ramyakrishna, Sravanthi Yamsani, Manjula Katkuri, and Parameshwar Aleti. "Formulation of Antiseptic Ointment from Mangifera Indica Seed and Leaf Powder Extracts." International Journal of Current Trends in Pharmaceutical Research 13, no. 1 (2025): 61–65. https://doi.org/10.30904/j.ijctpr.2025.4827.

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Background: Ointments are semisolid dosage form which usually actasvisco-elasticmaterials when shear stress is applied. They generally contain medicinal ingredients and are used to be applied externally to the body for therapeutic effect. Aim: Medicinal plant parts and extracts have been the focus of several researches. This is because there is increasing need to develop novel therapeutic and pharmaceutical products as alternatives to synthetic products. Materials and Methods: Mangifera indica, commonly used herb in ayurvedic medicine. Although review articles on this plant arealready publishe

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Revathi, D.* and Rajeswari M**. "WOUND HEALING ACTIVITY OF GUETTARDA SPECIOSA LINN." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 08 (2018): 7896–903. https://doi.org/10.5281/zenodo.1402711.

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<em>Traditionally the plant diversity was conserved through the temple premises based on their medicinal values. Medicinal activities of many temple plants are scientifically unexplored. The present research was focused to evaluate the wound healing activity of the sacred tree Guettarda speciosa commonly known as Indian lavender which is conserved in many temples and also promoted to grown as ornamental. The plant leaf is enriched with alkaloids, flavonoids, phenols, tannins, terpenoids, etc. Traditionally the leaf is used in cuts and wounds. Hence, the present research carried out to find the

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Wei, Chen, Florenly Florenly, Dewi Riastawaty Purba, and Fioni Fioni. "The Healing Analysis of II Degree Burn from Surgery Essential Oil Ointment (Curcuma Longa) in Wistar Rats (Rattus Norvegicus)." Budapest International Research in Exact Sciences (BirEx) Journal 4, no. 1 (2021): 31–42. http://dx.doi.org/10.33258/birex.v4i1.3474.

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Data in Indonesia the death rate from burns is still high at around 40%, mainly caused by severe burns. The most potential medicinal turmeric plant is its rhizome, which contains the phenolic compound curcumin and essential oils. Some of the benefits of turmeric antioxidants, anti-inflammatory, anti-cancer, acetylcholinesterase activity inhibitors, anti-fungal, and anti-bacterial. This study aims to find out the phytochemical content and effects of Turmeric Essential Oil Ointment (Curcuma longa Linn) in curing grade II burns in Wistar rats (Rattus norvegicus). This type of research is experime

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Jadhav, Mr Vinayak Devidas. "Review on: Herbal Ointment." International Journal for Research in Applied Science and Engineering Technology 13, no. 4 (2025): 5637–42. https://doi.org/10.22214/ijraset.2025.69615.

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Various areas where modern medicine is available, but the majority of the peoples in developing countries utilizes plants or plant preparations in their regular health care, many plant species have been proved to to possess antioxidant, antibacterial, and anti-inflammatory effects.A semisolid dose form, ointments often behave as visco-elastic materials under shear stress. Typically, they are given externally to the body to produce a therapeutic effect and include medicinal components. Natural medicines are also made in the form of ointments, along with various dosage forms. Numerous medicinal

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Vaishnavi, Mahajan* Swapnali Kondke Ashwini Pundkar Manjusha Markad Prachi Murkute Dr. Santosh Payghan. "Development of Herbal Anti-inflammatory Ointment." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1463–72. https://doi.org/10.5281/zenodo.15201863.

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Even in areas where modern medicine is available, the interest on herbal medicines and their utilization have been increasing rapidly in recent years. Plant derived substances and herbal medicines have recently attracted to great interest towards their versatile application, as medicinal plant are the richest source of bioactive compounds used in traditional and modern medicines. The present work is to formulate and evaluate the herbal ointment containing Shamipatra leaves extract. The ethanolic extract were prepared by using ultra sonic extraction method. Ointment base was prepared and formul

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Growther, Lali, G. Bavatharani, and K. Sukirtha. "Secondary metabolite profile, antioxidant activity and antimicrobial potency of Acalypha indica extract impacting the reproducibility of pharmacological applications due to seasonal variations." Medicinal Plants - International Journal of Phytomedicines and Related Industries 17, no. 2 (2025): 354–59. https://doi.org/10.5958/0975-6892.2025.00034.1.

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AbstractInterest in plant-based antimicrobial formulations has increased as a result of pathogenic bacteria’s growing resistance to synthetic antibiotics. Because of its complex phytochemical composition, which includes flavonoids, tannins and saponins, Acalypha indica, a medicinal plant that has long been utilized in Ayurveda and folk medicine, has been shown to have potent antibacterial properties. The purpose of this study is to formulate and assess the antibacterial ointment with extracts from A. indica for possible application in treating skin infections and wounds. The plant materials we

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Nasirah, Maulidia Ajhar, De Lux Putra Effendy, and Salim Emil. "Formulation of ointment from extract and fractions of Castanopsis costata leaves." World Journal of Advanced Research and Reviews 17, no. 1 (2023): 230–35. https://doi.org/10.5281/zenodo.8053964.

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<strong>Background: </strong><em>Castanopsis costata</em> (Blume) A. DC. or commonly known as cep-cepan is a medicinal plant widely used based on experience by Karo people in Indonesia n the Karo community for the treatment of wounds. However, no research has been done to prove this experience. Initially, the formulation of ointment extract and leaf fractions of <em>C. costata </em>need to be carried out. <strong>Aim: </strong>The purpose of this study was to provide information about the chemical group content contained in <em>C. costata</em> leaf extract an

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Megawati, Megawati, and Yuniharce Kadang. "The physical quality test formulation of ethyl acetate extract of kawista fruit peel (Limonia Acidissima L.) Ointment as an antibacterial against propionibacterium acnes." Jurnal Ilmiah Kesehatan Sandi Husada 13, no. 2 (2024): 321–28. http://dx.doi.org/10.35816/jiskh.v13i2.1219.

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Introduction: Using medicinal plants in Indonesia still needs to be optimized. Almost all parts of the Kawista plant have been traditionally used to treat various ailments such as antioxidants, antidiabetic, wound healing, and controlling uric acid levels. Existing research on Kawista fruit peel as an acne antibacterial includes studies on the ethyl acetate extract of Kawista fruit peel against Propionibacterium acnes, which falls into the moderate to strong category. In Indonesia, Kawista fruit is limited to the flesh and is used to make syrup and dodol (a traditional sweet). In contrast, the

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Shukla, Renuka, and Varsha Kashaw. "Development, characterization and evaluation of poly-herbal ointment and Gel formulation containing Nerium Indicum Mill, Artocarpus Heterophyllus Lam, Murraya Koenigii Linn, Punica Granatum Linn." Journal of Drug Delivery and Therapeutics 9, no. 2 (2019): 64–69. http://dx.doi.org/10.22270/jddt.v9i2.2381.

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Objective: The objective of present study was the development, characterization and evaluation of poly-herbal ointment and gel formulations of Nerium Indicum Mill, Artocarpus Heterophyllus Lam, Murraya Koenigii Linn, Punica Granatum Linn extract. Plant derived substances and herbal medicines have recently attracted the great interest towards their versatile application. Medicinal plants are the richest source of bioactive compounds used in traditional and modern medicine. The ointment and gel formulation of plant extract has a sound approach, The poly-herbal ointment and gel formulation were e

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Lulseged, Kalkidan, Muluemebet Zinabu Akele, Alfoalem Araba Abiye, Besufekad Abebe, and Solomon Assefa Huluka. "Wound Healing and Antioxidant Properties of 80% Methanol Leaf Extract of Verbascum sinaiticum (Scrophulariaceae): An Ethiopian Medicinal Plant." Evidence-Based Complementary and Alternative Medicine 2022 (September 8, 2022): 1–10. http://dx.doi.org/10.1155/2022/9836773.

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Wounds account for severe morbidity, socioeconomic distress, and mortality around the globe. For several years, various herbal products are used to expedite and augment the innate wound healing process. In Ethiopian folkloric medicine, Verbascum sinaiticum L. (V. sinaiticum) is commonly applied as a wound-healing agent. The present study investigated the potential wound healing and antioxidant properties of hydroalcoholic leaf extract of V. sinaiticum. The 80% methanol extract, formulated as 5% (w/w) and 10% (w/w) ointments, was evaluated in excision and incision wound models using nitrofurazo

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Rahman, Shaziea, and Bidhan Chandra Das. "Anthelmintic efficacy of some medicinal plants to control mange in goat in Bangladesh." Research in Agriculture Livestock and Fisheries 6, no. 3 (2020): 389–96. http://dx.doi.org/10.3329/ralf.v6i3.44804.

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Parasitism is an important limiting factor that responsible for deteriorating the health and productivity of livestock. Goat rearing is hindered by various problems, among them parasitism is an important limiting factor in Bangladesh as the climatic condition of the country favors the development and survival of various parasites. Of the parasitic problems, ectoparasitic infestations are commonly seen in goats. Common ectoparasites of animals are ticks, lice and mites which cause considerable amount of blood loss, irritation and annoyance. Mange infested goats bite and rub the affected area so

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Tatu, Alin Laurentiu, Alina Mihaela Elisei, Oana Lificiu, Camelia Diaconu, Magdalena Miulescu, and Olimpia Dumitriu Buzia. "Formulation, Preparation , Physico-Chemical, Microbiological Analysis and Clinical Uses of Capsaicin Microemulsions." Revista de Chimie 70, no. 4 (2019): 1278–82. http://dx.doi.org/10.37358/rc.19.4.7109.

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The present paper aims at creating a pharmaceutical formulation, i.e. microemulsion with capsaicin as the active principle; the purpose was to solubilize capsaicin and draw up pseudoternary phase diagrams establishing the microemulsion domains. We created a pharmaceutical form: capsaicin ointment, aiming at releasing capsaicin in the microemulsion and ointment bases. Comparative microbiological determinations were performed between microemulsion and ointment. The novelty of the study is formulating microemulsions as a means of solving solubility issues and increasing the bioavailability of med

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Lima de Souza, Kamila, Adriana Caroprezo Morini, Elaine Cristina Pacheco de Oliveira, et al. "AVALIAÇÃO DA TOXICIDADE DA OLEORRESINA DE COPAÍBA (Copaifera reticulata Ducke) IN NATURA E EM POMADAS NA PELE DE RATAS WISTAR." Acta Biologica Brasiliensia 8, no. 1 (2025): 19–28. https://doi.org/10.18554/0c01w621.

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The use of medicinal plants without caution and monitoring can cause reactions of intrinsic and extrinsic causes. Research aimed at the safe use of medicinal plants is still scarce, therefore, the objective of this work is to evaluate the dermal toxicity of oleoresin from copaiba, one of the main natural resources used for various therapeutic purposes by the traditional community. To verify the dermal toxicity of C. reticulata Ducke ointment, the recommendations of the Organization for Economic Cooperation and Development (OECD) 404/2015 protocol were used, both in natura form and as a 10% oin

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Kim, Eng-Chan. "The Oxidation of Magnetic Particles in Medicinal Ointment." Journal of Magnetics 17, no. 2 (2012): 83–85. http://dx.doi.org/10.4283/jmag.2012.17.2.083.

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Qamariah, Nurul, Rezqi Handayani, and Ahmad Irza Mahendra. "Uji Hedonik dan Daya Simpan Sediaan Salep Ekstrak Etanol Umbi Hati Tanah." Jurnal Surya Medika 7, no. 2 (2022): 124–31. http://dx.doi.org/10.33084/jsm.v7i2.3213.

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The Tanah Hati plant is one of the medicinal plants that have benefits as traditional medicine and is used by the people of the city of Palangka Raya, Central Kalimantan Province. Empirically this plant tuber is believed to treat wounds, postpartum wounds, malaria, and diarrhea. The ethanol extract of the Hati Tanah tuber has been made into an innovative pharmaceutical preparation in the form of an ointment. Hati Tanah tuber ethanol extract ointment is intended to inhibit wound infection caused by the bacteria Staphylococcus aureus. The purpose of this study was to determine the level of prefe

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Shivprasad, Chate* Dhanashree Cholke Mayur Bhosle. "Development And Evaluation of Polyherbal Ointment Containing Tridex Procumbens." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1087–104. https://doi.org/10.5281/zenodo.15354499.

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The increasing demand for natural wound care products has led to the exploration of polyherbal formulations that combine the therapeutic benefits of multiple medicinal plants. This study aimed to develop and evaluate a polyherbal ointment containing ethanolic extracts of Tridax procumbens, Ocimum sanctum (Tulsi), Curcuma longa (Turmeric), and Azadirachta indica (Neem) — all renowned for their antimicrobial, anti-inflammatory, antioxidant, and wound healing properties. The ointment was formulated using a standard ointment base and subjected to comprehensive evaluation, including physicoch

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Sawant, Shubhangi E., and Monali D. Tajane. "Formulation and evaluation of herbal ointment containing Neem and Turmeric extract." Journal of Scientific and Innovative Research 5, no. 4 (2016): 149–51. http://dx.doi.org/10.31254/jsir.2016.5410.

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Even in areas where modern medicine is available, the interest on herbal medicines and their utilization have been increasing rapidly in recent years. Plant derived substances and herbal medicines have recently attracted the great interest towards their versatile application, as medicinal plants are the richest source of bioactive compounds used in traditional and modern medicine. The present work is to formulate and evaluate the ointment of Neem (Azadirachta indica) and Turmeric (Curcuma longa) extract. The ethanolic extracts were prepared by using maceration method. The ointment base was pre

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Пучкан, Л. О., О. О. Салій, Л. А. Фуклева, and М. М. Малецький. "Development and research of ointment with essential oil of thyme for the treatment of the scalp and hair parts of the head." Farmatsevtychnyi zhurnal, no. 2 (April 26, 2023): 31–40. http://dx.doi.org/10.32352/0367-3057.2.23.04.

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Dermatological diseases are the most widespread in the whole world. According to WHO, 20–30% of the world's population suffers from fungal skin diseases and 25–35% from pustular diseases. Pustular diseases (pyoderma) are the result of pathogenic staphylococci and streptococci, and fungal diseases (dermatomycoses) are caused by various types of fungi. Today, these diseases are treated with various types of drugs, but the active ingredient in almost all of them is synthetic compounds (antibiotics, sulfonamides, imidazole derivatives, etc.). Medicines of natural origin are scarce. In order to inc

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Annissha Azzahra Wurnasari, Kusumaningtyas Siwi Artini, and Bangkit Riska Permata. "Uji Efektivitas Sediaan Salep Ekstrak Daun Kenikir (Cosmos Caudatus Kunth) Terhadap Penyembuhan Luka Sayat Pada Kelinci Jantan New Zealand White." Jurnal Medika Nusantara 1, no. 4 (2023): 337–53. http://dx.doi.org/10.59680/medika.v1i4.635.

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Kenikir Leaf Extract (Cosmos Caudatus Kunth) is a medicinal plant that can be used to heal cut wounds. This research aims to determine the compound content in kenikir leaves, determine the physical quality and stability of kenikir leaf extract ointment preparations, and determine the effective concentration for healing cuts on the backs of male New Zealand White rabbits. This type of research is experimental, making ointment formulations using kenikir leaf extract made in 3 concentrations, namely 10%, 15% and 20%. In ointment testing, organoleptic tests, homogeneity tests, spreadability tests,

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Stavskiy, Е. А., Т. V. Teplyakova, А. P. Nadeev, et al. "EXPERIMENTAL STUDY OF THE HEALING PROPERTIES OF BIOSEPTIN OINTMENT." Sibirskij medicinskij vestnik 7, no. 4 (2023): 47–57. http://dx.doi.org/10.31549/2541-8289-2023-7-4-47-57.

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Introduction. Due to the acquisition of resistance to antibiotics by pyogenic microbiota, the problem of local (medicinal) treatment of wounds has become more acute. Aim. Evaluation of the medicinal properties of Bioseptin ointment in vivo on a model of a purulent incised skin wound of research animals. Materials and object of the research. Bioseptin ointment was developed by LLC “Research Center”. The active principle of the ointment is a microbial association: bacteria Baсillus subtilis strain VKPМ B-7048 and Bacillus licheniformis strain VKPМ B-7038, which has high antagonistic activity aga

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Jurowski, Kamil, and Mirosław Krośniak. "The Toxicological Risk Assessment of Dermal Exposure of Patients Exposed to Lead and Cadmium Due to Application of Ointments with Marjoram Herb Extract (Majoranae herbae extractum)." International Journal of Environmental Research and Public Health 20, no. 3 (2023): 2701. http://dx.doi.org/10.3390/ijerph20032701.

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Potential heavy metal impurities (HMI) in pharmaceuticals/pharmaceutical products/drugs based on plant raw materials (e.g., herbs) are an important problem in the pharmaceutical industry; however, there is a lack of scientific articles on the comprehensive toxicological risk assessment of HMI in ointment applied dermally. To make the appropriate toxicological risk assessment, we consider: (1) the raw results of the levels of lead and cadmium in the ointments (metal per kg of mass), (2) one-time administration of the applied ointment, (3) daily exposure of Pb and Cd in the applied ointments acc

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Mozhaiev, Ivan, Tetyana Nosalska, Inna Dovha, Viktoriia Yevsiukova, and Victor Kazmyrchuk. "Preclinical studies of the combined ointment based on walnut extract." Annals of Mechnikov Institute, no. 3 (September 20, 2024): 47–49. https://doi.org/10.5281/zenodo.13819889.

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Currently, the treatment of wound infection and its complications is an urgent problem in medicine. Gunshot and shrapnel injuries are characterized by the greatest severity, multiple, combined and multi-component nature of damage. In this regard, much attention is paid to the development and use of antimicrobial agents for the local treatment of purulent-inflammatory processes, primarily based on plant extracts. The advantage of using medicinal plants and phytopreparations in medical practice is their low toxicity and absence of pronounced side effects. A combined medicinal product for the tre

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Liu, Yi-Shan, Mei-Chou Lai, Tang-Yao Hong, and I.-Min Liu. "Exploring the Wound Healing Potential of Hispidin." Nutrients 16, no. 18 (2024): 3161. http://dx.doi.org/10.3390/nu16183161.

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Background: Hispidin, a polyphenol component mainly derived from the medicinal mushroom species Phellinus and Inonotus, shows promise for biomedical applications, yet its potential in wound healing remains largely unexplored. This research investigates the wound healing effects of hispidin through in vitro and in vivo experiments, while also evaluating its antimicrobial properties and safety profile. Methods: In vitro scratch assays were conducted to evaluate the impact of hispidin on the migration of NIH-3T3 cells. The wound healing potential of hispidin was assessed in rats using excision wo

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Cheshfar, Fatemeh, Soheila Bani, Mojgan Mirghafourvand, Shirin Hasanpour, and Yousef Javadzadeh. "The Effects of Ginger (Zingiber officinale) Extract Ointment on Pain and Episiotomy Wound Healing in Nulliparous Women: A Randomized Clinical Trial." Journal of Caring Sciences 12, no. 3 (2023): 181–87. http://dx.doi.org/10.34172/jcs.2023.31842.

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Introduction: Episiotomy is a usual midwifery surgery. Iran is a country with an abundant source of medicinal plants. This study aimed to investigate ginger extract ointment’s effects on the pain and recovery of episiotomy incisions in nulliparous women. Methods: This randomized clinical trial was conducted in a public hospital in Iran on 70 nulliparous women with an episiotomy incision. The women were randomly assigned to ginger extract ointment and placebo groups. The primary outcomes included pain and wound healing that were assessed using a visual analog scale (VAS), redness, edema, ecchym

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Liu, Yi-Shan, Mei-Chou Lai, Yu-Cheng Tzeng, and I.-Min Liu. "Polyphenolic Hispolon Derived from Medicinal Mushrooms of the Inonotus and Phellinus Genera Promotes Wound Healing in Hyperglycemia-Induced Impairments." Nutrients 17, no. 2 (2025): 266. https://doi.org/10.3390/nu17020266.

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Background: This study investigated the wound-healing potential of hispolon, a polyphenolic pigment derived from medicinal mushrooms, under diabetic conditions using both in vitro and in vivo models. Methods: In the in vitro assays, L929 fibroblast cells exposed to high glucose (33 mmol/L) were treated with hispolon at concentrations of 2.5, 5, 7.5, or 10 μmol/L. In the in vivo assays, streptozotocin-induced diabetic rats with excision wounds received daily topical applications of 0.2 g of 5% (w/w) hispolon ointment. Results: Hispolon improved cell viability; suppressed oxidative stress by red

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Gaurav Singh and Krishanu Samanta. "Preliminary physico – phytochemical and phytocognostical evaluation of the leaves parts and evaluation of herbal ointment using leaves of Achyranthes aspera L. Leaf extract." World Journal of Advanced Research and Reviews 14, no. 2 (2022): 443–52. http://dx.doi.org/10.30574/wjarr.2022.14.2.0448.

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Herbal plants are huge sources of neutraceuticals, prevent the different disease or maintain healthy life. Plant produces primary metabolites for their basic survival and secondary metabolites for their ecological, taxonomical and biochemical differentiation and diversity. Achyranthes aspera L. (Family Amaranthaceae) are broadly used in traditional system of medicine throughout different part of India, South Andaman Island, Pacific Island, Baluchistan, Tropical Asia, America, and Australia. It has great medicinal importance like to stomach tonic, diuretic, laxative, anthelmintic, anti hyperlip

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Tole, S.B, N.D. Demgunde, A.A. Joshi, and S.L Korekar. ""Formulation of Morinda Wound Healing Ointment"." International Journal of Management and Humanities (IJMH) 4, no. 9 (2020): 80–84. https://doi.org/10.35940/ijmh.I0895.054920.

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The biological process of Wound healing comprises the trauma and pathologic condition of the oral mucosa.For this requires proper management so the wound heal faster and without any complication.The strong indicator of wound healing is the increase in number of fibroblast cells in the oral mucosa. The remodelling phase of wound healing shows decreasing fibroblast cell proliferation and then collagen fibres are synthesized. Noni plant have tremendous medicinal uses, by observing this fact Noni leaf (Morinda citrifolia L.), a part of the noni plant, was successfully used in present research to m

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Yanira Zaita Ferrer, Leonor I. Parra Flores, Rigoberto Fimia Duarte, et al. "Aloe vera and Bixa orellana in a revitalizing ointment for cattle skin injuries." GSC Biological and Pharmaceutical Sciences 20, no. 1 (2022): 001–11. http://dx.doi.org/10.30574/gscbps.2022.20.1.0256.

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Phytopharmaceuticals constitute a therapy that, when carried out on a scientific basis, becomes a necessary, safe, effective and, above all, economical alternative in the confrontation of diseases that affect humans and other animals, for the achievement of health. The objective of the research was to evaluate the effectiveness of a revitalizing ointment of Aloe vera L and Bixa orellana L for skin lesions in cattle. The methods used correspond to the transversal research for case control, a total of 76 animals of the classified by categories, females and males of mestizo breeds, belonging to t

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Yadav Abhishek and Samanta Krishanu. "Formulation and evaluation of herbal ointment using Emblica officinalis extract." World Journal of Advanced Research and Reviews 9, no. 2 (2021): 032–37. http://dx.doi.org/10.30574/wjarr.2021.9.2.0040.

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Herbal medicine prepare various part of plant are used like flower, leaves, seeds, root etc. Instead off an herbal drug is design as the alternative formulation for the external use in the form of ointment. For the medicinal use the herbal ointment apply externally on human body. The main aims of this research are preparation of herbal ointment from the Emblica officinalis plants the antibacterial activity. Under this research work, it is design as herbal ointment with the help of methanolic extract of Emblica officinalis and determines the anti-bacterial capacity on it. In vitro study the ant

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Tbeekh, Haifa T. Abu, Hamoodi Aliwi Mosa, and Mohammed Hamoudi Alsunboli. "Efficacy of Verapamil Combined with Zinc Oxide for Anal Fissure Management." Journal Port Science Research 7, issue (2024): 545–48. http://dx.doi.org/10.36371/port.2024.special.42.

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Anal fissure are common causes of rectal bleeding; often necessitate effective local medicinal treatments to avoid surgical intervention. This study evaluates the efficacy of a novel combination therapy using verapamil and zinc oxide ointment for the management of chronic anal fissure. Verapamil, a calcium channel blocker, reduces sphincter pressure, while zinc oxide promotes healing through its anti-inflammatory properties. Conducted as a prospective randomized controlled trial, 65 patients were divided into three groups: a control group treated with Vaseline, a group treated with 15% verapam

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Nurhidayah Nurhidayah and Alifa Fitrah. "Formulasi Sediaan Salep Ekstrak Etanol Bawang Putih (Allium Sativum) dengan Variasi Basis." OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan 3, no. 1 (2025): 179–88. https://doi.org/10.61132/obat.v3i1.1010.

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Garlic is a medicinal plant that is widely used for health and is used by people for traditional medicine. Garlic contains various secondary metabolite compounds which have antifungal activity, including tannins, flavonoids, allicin. Flavonoids are the largest group of phenolic compounds. So it is possible that flavonoids also have an effective antifungal effect. This research aims to formulate an ethanol extract of garlic (Allium sativum) ointment with a variety of bases and to determine the physical quality of the ointment. The type of research is laboratory experimental. The method used is

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Priyanka, Raut Manisha Mishra Gayatri Bawane Ayushi Ambade Alshapha Anjum Khan Abhilasha Thakur Isha Patle. "Formulation And Evaluation Of Herbal Anti-Bacterial Crack Heel Ointment Using Thuja Occidentalis Leaves Extract And Euphorbia Caducifolia Juice." International Journal of Pharmaceutical Sciences 2, no. 4 (2024): 611–22. https://doi.org/10.5281/zenodo.10968574.

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Herbal preparation has its origins in ancient cultures. It involves the medicinal use of plants to treat disease and enhance general health and wellbeing pharmaceutical medications are based on manmade versions of naturally occurring compounds found in plants. For example, crack heels can be cured by<em> Thuja occidentalis </em>extract and <em>Euphorbia Caducifolia </em>Juice. The present research has been undertaken with the aim of formulate and evaluate the herbal ointment containing <em>Thuja occidentalis </em>extract and <em>Euphorbia Caducifolia</em> juice. The ointment formulations were

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Gnanasekaran, Jothi, Keerthana K, Shobana G, Radhika J, and Kadhiravan M. "HEALING POTENTIAL OF A POLYHERBAL OINTMENT ON EXCISION WOUND IN NORMAL AND DIABETES INDUCED ALBINO RATS." Asian Journal of Pharmaceutical and Clinical Research 10, no. 4 (2017): 41. http://dx.doi.org/10.22159/ajpcr.2017.v10i4.11589.

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Objective: Wound healing potential of polyherbal ointment prepared from Cordial oblique Willd., Dentophote falcate (L.f) Ettingsh., and Vigna radiate Linn. has been evaluated, Preclinical studies were carried out using albino rats as experiment models.Methods: Animals were divided into 6 groups, each groups comprising of 6 rats. Group I, II and III are normal excision wounded rats that were categorized as normal untreated, polyherbal ointment treated and standard ointment treated respectively. Groups IV, V and VI were induced with diabetes using alloxan monohydrate (150mg/kg bw; ip single dose

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