Academic literature on the topic 'Medicinal plant extracts'

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Journal articles on the topic "Medicinal plant extracts"

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Vicaș, Laura Grațiela, and Mariana Eugenia Mureșan. "Medicinal Plant Extracts." Plants 10, no. 5 (April 22, 2021): 838. http://dx.doi.org/10.3390/plants10050838.

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Solowey, Elisha, Michal Lichtenstein, Sarah Sallon, Helena Paavilainen, Elaine Solowey, and Haya Lorberboum-Galski. "Evaluating Medicinal Plants for Anticancer Activity." Scientific World Journal 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/721402.

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Plants have been used for medical purposes since the beginning of human history and are the basis of modern medicine. Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives. Our hypothesis was that whole plant extracts selected according to ethnobotanical sources of historical use might contain multiple molecules with antitumor activities that could be very effective in killing human cancer cells. This study examined the effects of three whole plant extracts (ethanol extraction) on human tumor cells. The extracts were fromUrtica membranacea(Urticaceae),Artemesia monosperma(Asteraceae), andOriganum dayi post(Labiatae). All three plant extracts exhibited dose- and time-dependent killing capabilities in various human derived tumor cell lines and primary cultures established from patients’ biopsies. The killing activity was specific toward tumor cells, as the plant extracts had no effect on primary cultures of healthy human cells. Cell death caused by the whole plant extracts is via apoptosis. Plant extract 5 (Urtica membranacea) showed particularly strong anticancer capabilities since it inhibited actual tumor progression in a breast adenocarcinoma mouse model. Our results suggest that whole plant extracts are promising anticancer reagents.
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Jangid, Renu, and Tahira vbegum. "Antimycotic Activity of Leaf Extracts of Medicinal Plants Against Dermatophytes." Journal of Fungal Diversity 1, no. 1 (November 10, 2020): 33–40. http://dx.doi.org/10.14302/issn.2766-869x.jfd-20-3603.

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Plant products have been used as medicines against fungal infectious diseases. In this research antimycotic activity of the leaf extracts of five medicinal plants (Nerium indicum, Catheranthus roseus, Lantana camera, Ziziphus mauritiana) were tested against three dermatophytes (Trichophyton mentagrophytes, Trichophyton rubrum and Microsporum. gypseum). Development of more effective and less toxic antimycotic agents is required for the treatment of dermatophytosis. The plant materials were extracted with methanol, ethanol and diethyl ether solvent to investigate their antimycotic activities in Vitro. Ethanol and methanol extracts of all selected medicinal plants were showed the positive activity against all tested dermatophytes. Diethyl ether extract was showed lowest activity against T. mentagrophytes and T. rubrum and showed moderate activity against M. gypseum. The three dermatophytes differed with regard to their susceptibility to plant extracts.
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Fraser, Marie-Hélène, Alain Cuerrier, Pierre S. Haddad, John T. Arnason, Patrick L. Owen, and Timothy Johns. "Medicinal plants of Cree communities (Québec, Canada): antioxidant activity of plants used to treat type 2 diabetes symptomsThis article is one of a selection of papers published in this special issue (part 2 of 2) on the Safety and Efficacy of Natural Health Products." Canadian Journal of Physiology and Pharmacology 85, no. 11 (November 2007): 1200–1214. http://dx.doi.org/10.1139/y07-108.

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Traditional medicines (TM) used to treat symptoms of diabetes by two Cree communities were assessed for their free radical scavenging activity using the stable 1,1-diphenyl-2-picrylhydrazyl radical, and their ability to protect human low-density lipoprotein from Cu2+-mediated oxidation by measuring lag time before the appearance of conjugated dienes and formation of thiobarbituric acid-reactive substances. Water-soluble phenolic content was also measured. A total of 20 medicinal plants from Whapmagoostui and 16 from Mistissini were compared with 16 extracts of plants that were not used medicinally. Medicinal plant extracts, particularly those from Larix laricina, displayed high antioxidant activity, comparable with ascorbic acid, Trolox, and the known antioxidant flavonoids quercetin, epicatechin, catechin. Extracts of Pinaceae and Ericaceae contained the highest levels of phenolics. Factors such as season and area of plant collection, as well as the plant part from which the extract was derived, affected antioxidant activity. Positive correlations were found between the established traditional knowledge of Cree Elders and Healers and the antioxidant activity for medicinal plants used in Mistissini (r = 0.3134; p = 0.058) and in Whapmagoostui (r = 0.5165; p = 0.001). Significant correlations between phenolic content were also seen with the existing ethnobotanical data (r = 0.5015; p = 0.003) and bioassays (r = 0.4178; p = 0.003). These results indicate that a clear majority of plants used by the Cree are excellent sources of antioxidants.
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Uddin, Shaikh J., I. Darren Grice, and Evelin Tiralongo. "Cytotoxic Effects of Bangladeshi Medicinal Plant Extracts." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–7. http://dx.doi.org/10.1093/ecam/nep111.

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To investigate the cytotoxic effect of some Bangladeshi medicinal plant extracts, 16 Bangladeshi medicinal plants were successively extracted withn-hexane, dichloromethane, methanol and water. The methanolic and aqueous extracts were screened for cytotoxic activity against healthy mouse fibroblasts (NIH3T3) and three human cancer-cell lines (gastric: AGS; colon: HT-29; and breast: MDA-MB-435S) using the MTT assay. Two methanolic extracts (Hygrophila auriculataandHibiscus tiliaceous) and one aqueous extract (Limnophila indica) showed no toxicity against healthy mouse fibroblasts, but selective cytotoxicity against breast cancer cells (IC501.1–1.6 mg mL−1). Seven methanolic extracts fromL. indica,Clerodendron inerme,Cynometra ramiflora,Xylocarpus moluccensis,Argemone mexicana,Ammannia bacciferaandAcrostichum aureumand four aqueous extracts fromHygrophila auriculata,Bruguiera gymnorrhiza,X. moluccensisandAegiceras corniculatumshowed low toxicity (IC50> 2.5 mg mL−1) against mouse fibroblasts but selective cytotoxicity (IC500.2–2.3 mg mL−1) against different cancer cell lines. The methanolic extract ofBlumea lacerashowed the highest cytotoxicity (IC500.01–0.08 mg mL−1) against all tested cell lines among all extracts tested in this study. For some of the plants their traditional use as anticancer treatments correlates with the cytotoxic results, whereas for others so far unknown cytotoxic activities were identified.
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Gouramma Patil and Sharanabasappa B Patil. "Biological synthesis of Nanoparticles from Medicinal Plants: Recent Studies." International Journal of Research in Pharmaceutical Sciences 12, no. 1 (January 13, 2021): 344–49. http://dx.doi.org/10.26452/ijrps.v12i1.4142.

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In a recent trend, nanotechnology has been developed to be an important field of research in various fields like medicinal chemistry, pharmaceuticals and all. On the other hand, compared to chemical method of synthesis, method of synthesis of nanoparticles by green method is simple, effective & ecofriendly. Plant extracts are obtained from the plant, creep, cereals, etc. generally natural extracts are prepared by decoction method or solid powder formation method. The natural extracts are very much effective in the medicinal approach. The study of Nano sized particles towards natural extracts has given a novel way in the field of medicines. So from the nanomaterials of natural extracts, one can expect still good effective results. As we know that preparation of nanoparticles through green approach is one of the good selections in the view of betterment of ecology. Therefore by taking aqueous extracts of medicinal plants’ parts and metal ions, nanoparticles can be synthesized. The plant extract and metal ions are taken in a fixed ratio and keep at room temperature for the reduction. The Changes in the Color confirmed the formation of nanoparticles. Further, the synthesized nanoparticles were characterized by UV, EPMA, XRD and FTIR data.
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Maharjan, Naresh, Anjana Singh, Mangala D. Manandhar, Shaila Basnyai, Binod Lekhak, and Surya K. Kalauni. "Evaluation of Antibacterial Activities of Medicinal Plants." Nepal Journal of Science and Technology 13, no. 2 (March 10, 2013): 209–14. http://dx.doi.org/10.3126/njst.v13i2.7738.

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Plant and plant products are used as medicine from the beginning of human civilization. This study compares the antibacterial activity of crude hexane, ethylacetate and methanol extracts of nine different medicinal plants used in traditional Nepalese medicine, tested against 10 species of bacteria: Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Klebsiella pneumoniae (ATCC 20063), Klebsiella oxytoca, Proteus mirabilis (ATCC 49132), Proteus vulgaris, Pseudomonas aeruginosa (ATCC 27853), Salmonella typhi, Salmonella paratyphi and Shigella dysenteriae by agar well diffusion method. The selected parts of these medicinal plants namely Acorus calamus (Rhizome), Aegle marmelos (Fruit), Asparagus racemosus (Tuberous root), Mimosa pudica (Root), Terminalia bellirica (Fruit), Terminalia chebula (Fruit), Tinospora cordifolia (Stem), Woodfordia fruticosa (Flower) and Holarrhena antidysenterica (Seed) were taken for study.The result showed that out of nine tested plants, four plant extracts (44%) showed activity against at least five or more tested bacteria and five plant extracts (56%) were active against three or less than three bacteria. None of the tested plant extracts was active against all the tested bacteria. A. racemosus was the least effective against bacterial species. S. aureus was the most susceptible bacteria being sensitive to 18 extracts from 9 medicinal plants. P. vulgaris was the most resistant bacteria being resistant to all selective plants. The MBC value ranges from 3.12 mg/ml to >50 mg/ml. Lowest MBC was shown by ethylacetate extract of T. bellirica against E. coli and ethylacetate extract of W. fruticosa against S. dysenteriae. Largest ZOI (31 mm) was produced by ethylacetate extract of T. bellirica. Nepal Journal of Science and Technology Vol. 13, No. 2 (2012) 209-214 DOI: http://dx.doi.org/10.3126/njst.v13i2.7738
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Sunayana Manipal, Lubna Fathima, Sajid T Hussain, and Venkat R. "Efficacy of anti-bacterial and anti-fungal action on four medicinal plants extract the A.arabica, T.chebula, A.indica, and V.vinifera against Streptococcus mutans and Candida albicans -An in-vitro study." International Journal of Research in Pharmaceutical Sciences 10, no. 4 (October 16, 2019): 3121–26. http://dx.doi.org/10.26452/ijrps.v10i4.1608.

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The aim of the study was to test the anti-bacterial, and anti-fungal activity of four medical plants extract the A.arabica, T.chebula, A.indica, and V.vinifera against the streptococcus mutants and Candida albicans organisms. The extracts obtained from the medicinal plant of A.arabica, T.chebula, A.indica, and V.vinifera was procured and powdered. The minimum inhibitory concentration of the obtained extracts was determined by using the tube dilution method, and the bacterial strains of Streptococcus mutants and Candida albicans were cultured into the extract obtained at a concentration of 1mg/ml, 500µg/ml, 250µg/ml, and 100µg/ml respectively. The extracts obtained from A.arabica and T.chebula had a better anti-bacterial property when compared to the other two medicinal plants and the extracts obtained from A.indica and V.vinifera had a better anti-fungal property when compared to the other two medicinal plants. These plants extracts showed the anti-bacterial property in previous studies to add on to the review of literature in our study it proved that A.indica and V.vinifera had a better anti-fungal activity when compared to another two medicinal plant extract. The clinical significance of the medicinal plant extract can be effectively used as an anti-bacterial and anti-fungal agent as it was compared with the gold standard values of Streptomycin and Amphotericin B.
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Kirui, J. K., K. Kotut, and P. O. Okemo. "Efficacy of aqueous plant extract in disinfecting water of different physicochemical properties." Journal of Water and Health 13, no. 3 (April 8, 2015): 848–52. http://dx.doi.org/10.2166/wh.2015.002.

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This study explored the possibility of disinfecting water using aqueous extracts of medicinal plants. Seven medicinal plants used by Samburu herbalists for the treatment of stomach illnesses were investigated for water disinfection. Aqueous extracts of the dried powdered plant material were directly used to treat the water samples collected. Efficacy of water treatment with medicinal plants expressed as percentage reduction in bacterial colonies revealed that Acacia nilotica extract with a mean percentage reduction of 99.86% was the most effective at reducing the number of bacterial colonies. Albizia anthelmintica extract with a mean of 9.47% was the least effective at reducing the number of bacterial colonies. The study also revealed a possible interaction between plant extracts and water source (P < 0.05, df = 54). The results obtained in this study point out a possibility of using aqueous extracts from A. nilotica in disinfecting water of different physicochemical properties.
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Rashid, N., AA Paul, S. Islam, SA Sajib, K. Nasirujjaman, KMF Hoque, and MA Reza. "Studies on antioxidant potential, phytochemical properties and toxicity of four popular medicinal plants of Bangladesh." Journal of Bio-Science 25 (July 18, 2018): 27–37. http://dx.doi.org/10.3329/jbs.v25i0.37495.

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Medicinal plant extract has long been used successfully in ‘unani’ or ‘ayurvedic’ medicine. Medicinal plant extract contains bioactive molecules and activity of these molecules may help to mitigate, eradicate or cure diseases. In the advent for the search for new medicinally important bioactive molecule, the current paper deals with the anti-oxidative, cytotoxic and phytochemical analysis of Scoparia dulcis leaf and root, Curculigo orchioides root, Pandanus fascicularis root and Baccaurea sapida leaf extract. Aqueous and methanolic extracts were made for each of the extracts where they posses significant antioxidative properties. High activities were seen in P. fascicularis and S. dulcis plant extract where IC50 values were 21.87 μg/ml and 173.36 μg/ml respectively. In toxicity test, only P. fascicularis extracts showed lethality in a dose-dependent manner where the LD50 value was 25.64 μg/ml. By the phytochemical analysis, it was found that each of these plant species possesses glycosides, protein, carbohydrates, alkaloid, flavonoid etc. which are pharmacologically active biomolecules. These important properties of those plants showed an indication that these plants can further be tested for the utilization in therapeutic purpose or in cosmetic industry.J. bio-sci. 25: 27-37, 2017
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Dissertations / Theses on the topic "Medicinal plant extracts"

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Case, Olivia Hildegard. "An assessment of medicinal hemp plant extracts as natural antibiotic and immune modulation phytotherapies." Thesis, University of the Western Cape, 2005. http://etd.uwc.ac.za/index.php?module=etd&amp.

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This study aimed to evaluate the antimicrobial efficacy of medicinal hemp plant extracts to determine the antibacterial effects of indigenous Sansevieria species and exotic Cannabis sativa phytotherapy varieties. This study also assessed whether aqueous o
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Kudi, Ayuba Caleb. "Antiviral and antibacterial screening of some Nigerian medicinal plant extracts." Thesis, University of Leicester, 2000. http://hdl.handle.net/2381/29814.

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Plants from Northern Nigeria with a history of use in both human and veterinary traditional medicine have been investigated in vitro, for antiviral and antibacterial activity and their cytotoxicity against human cells in culture determined. Aqueous extracts were tested against poliovirus, astrovirus, human and Equine herpes simplex virus and canine and bovine parvovirus, using the microtitre plate inhibition test. Most of the extracts were non toxic to cells in culture and had activity against more than one virus at a dose rate of between 100 and 400 g/100. the most effective of the plant extracts were those of Bauhania thonningi, Anacardium occidentale, Boswelia dalzeilii, Dichrostacyls glomerata and Sterculia setigera, which were found to be active against all the viruses tested. In addition, most of the extracts were active against those Gram positive bacteria tested. Two of the plants, Anogeissus schimperi and Anacardium occidentale, had good antibacterial activity against the Gram negative bacteria Escherichia coli and Pseudomonas aeruginosa. Attempts were made to isolate and identify the active components in these extracts with activity against both viruses and bacteria using the gel filtration, ion-exchange chromatography and thin layer chromatography. Activities were associated with fractions identified as flavonoids, alkaloids, terpenoids and polyphenols and were found, either individually or in combination, to have antiviral action. A field trial of the active plant extracts was carried out using cattle with clinical diarrhoea and dysentery and comparing recovery patterns with similar administering extracts to cattle with clinically diagnosed diarrhoea animals treated with a broad spectrum gut-acting antibiotic, neomycin-sulphate. No significant difference (P=0.778) was seen between the extract and the antibiotic in efficacy of treatment.
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Zhu, Min. "CNS active principles from selected Chinese medicinal plants." Thesis, University College London (University of London), 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339881.

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Kgatle, Dimakatso Thomas. "Isolation and characterization of antioxidant compounds from Cambretum apiculatum (Sond.) subsp apiculatum leaf extracts." Electronic thesis, 2007. http://upetd.up.ac.za/thesis/available/etd-08122008-114732/.

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Tshidino, Shonisani Cathphonia. "Efficacy of two medical plant extracts and metformin in the prevention of diet induced fatty liver." Thesis, Nelson Mandela Metropolitan University, 2014. http://hdl.handle.net/10948/9066.

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Non‐alcoholic fatty liver diseases (NAFLD) is manifested in the absent of alcohol abuse. This disease is the major cause of liver failure and death among adults and children worldwide, including South Africa. Its increasing prevalence urges the need of therapeutic intervention. The main objectives of this study were to investigate the following: (1) The effect of 38.9% high fat diet (HFD)‐induced insulin resistance and fatty liver in male Wistar rats, (2) The efficacy of aqueous extracts from Sutherlandia frutescens leaves and Prunus africana bark and metformin in the treatment of HFDinduced insulin resistance and fatty liver. Male Wistar rats were fed on HFD (the HF group) or normal rat chow (the LF group) for 12 weeks. Even though the HFD‐fed rats had developed insulin resistance by week 12, fatty liver developed by week 16. After week 12, the HF group was divided into four groups of 6‐7 rats each and three of those groups were gavaged with either 0.125 mg P. africana extract/kg bwt/day (the HF+Pa group) or 50 mg S. frutescens extract kg bwt/day (the HF+Sf group) or 16 mg metformin/ kg bwt/day (HF+Met group), while kept on the same diet for an additional of 4 weeks, to investigate whether two medicinal plant extracts and metformin can prevent HFD to induce fatty liver or not. After 16 weeks, the liver histological images revealed that the HF group developed fatty liver in the form of both microsteatosis and macrosteatosis. Fatty liver was confirmed by significant increased liver total lipid (TL) and activities of glucose‐6‐phosphate dehydrogenase (cG6PD) and xanthine oxidase (XO), mitochondrial NADH oxidase (mNOX) and by a decrease (P<0.05) in the activities of the homogenate superoxide dismutase (hSOD) and mitochondrial complex II in the HF group, when compared to the LF group. Since the activities of mCS and cACL enzymes were not changed in the HF group, hence increased cG6PD activity in the HF group indicates that there was increased NADPH demand for lipid accumulation from activated NEFAs taken up by the liver from circulation and for maintenance of the NADPH‐dependent antioxidants and oxidants, respectively. The obtained data also show that mitochondria of the HFD‐fed rats adapted to an increase in energy availability, thereby compensation through decreasing complex II activity, to allow electron flux from β‐oxidation to respiratory chain in the HF group. Liver TL content was significantly decreased in the rats treated with metformin and P. africana extract, but not in the rats treated with S. frutescens when compared to the HF group (P < 0.05). However, the TL content remained >5% per liver weight in all treated groups. The present study demonstrates that these two plant extracts and metformin have different glucogenic and lipogenic effects from that presented by HFD alone when compared to the LFD alone. In conclusion, metformin and P. africana extract can attenuate HFD‐induced fatty liver without changing the dietary habits. Hence S. frutescens extract is less effective in the prevention of HFD‐induced fatty liver. A change in the dietary habits is recommended to be considered during the use of these three remedies in the treatment of HFD‐induced insulin resistance and fatty liver. All three treatments enhanced antioxidant capacity, and may improve insulin resistance and fatty liver mediated by the present HFD through different mechanism of actions in the liver.
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Baatjies, Lucinda. "In vitro cytotoxic effects of selected Nigerian medicinal plant extracts on cancer cell lines." Thesis, Nelson Mandela Metropolitan University, 2012. http://hdl.handle.net/10948/d1008191.

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Cancer is a disease that imposes a heavy burden on public health and poses a challenge to science. The World Health Organization estimates that 80 percent of people in developing countries of the world rely on traditional medicine for their primary health needs, and about 85 percent of traditional medicine involves the use of plant extracts. This is particularly true in Africa where a large percentage of the population depends upon medicinal plants for health care. Therefore, detailed screening and evaluation of bioactive substances for chemotherapeutic purposes of African plants are urgently warranted. Furthermore, this will serve to validate the efficacy and safety of African traditional medicine. The current study investigated the in vitro cytotoxic effects of 17 ethanolic extracts of the following 16 plants used in traditional anticancer medicine in Nigeria: Sapium ellipticum leaves, Sapium ellipticum stembark, Combretum paniculatum, Celosia trigyna, Pupalia lappacea, Justica extensa, Hedranthera barteri leaves, Alternanthera sessilis, Ethulia conyzoides leaves, Lannea nigritana stembark, Combretum zenkeri root, Combretum molle leaves, Adenanthera parvoniana, Lannea acida, Cyathula achyranthoides, Drymaria cordata, Cyathula prostrata, against HeLa cancer cells. Five of the most promising extracts (Sapium ellipticum leaves, Combretum paniculatum, Celosia trigyna, Drymaria cordata, Cyathula prostrata) were selected for further screening against HT29 and MCF-7 cancer cells. Of the five, the first two were investigated further based on their activities in the screening phase. The S. ellipticum leaf extract yielded IC50 values of 88.60 ± 0.03 and 93.03 ± 0.03 μg/ml against HeLa and MCF-7, respectively. The toxicity was also evaluated on normal cells and an IC50 of 77.66 μg/ml was obtained for peripheral blood mononuclear cells (PBMCs). The IC50 values for proliferating and confluent Chang liver cells were both >125 μg/ml. These results suggest that the extract may be selective for specific cell types. Bio-assay guided fractionation of the S. ellipticum ethanolic extract yielded two active fractions; chloroform and ethyl acetate. Two compounds isolated from the chloroform extract were screened against the three cancer cell lines and found to be inactive. Three compounds were isolated from the ethyl acetate fraction and revealed IC50 values < 62.5 and < 31 μg/ml against MCF-7. Unfortunately these two compounds soon lost activity before any further work could be done on them and work was continued with the crude extract.
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Vries, Filicity Ann. "Synergistic effects of mixtures of fungicides and medicinal plant extracts against Botrytis cinerea." Thesis, University of the Western Cape, 2008. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_6798_1372423235.

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We hypothesize that South African medicinal plants contain compounds that can act in synergism with synthetic antifungal compounds. Four fungicides - Sporekill&trade
, Rovral&trade
, Terminator&trade
and Teldor&trade
at doses 0.1, 0.2, 0.4 and 0.8 mL L-1 and plant species Galenia africana, Elytropappus rhinocerotis and Tulbaghia violacea were tested aloneand in different combinations for their potency (efficacy) on radial growth inhibition of Botrytis cinerea strains on potato dextrose plates. Four doses of plant extract for each of the respective plant species were used. A total of 48 combinations were tested for each strain. Mixtures of plant extracts were far more effective in controlling strains compared to the individual components alone, representing significant levels of in vitro synergistic interactions. Combinations of these components represent an attractive future prospect for the development of new management strategies for controlling B. cinerea. Since the in vitro tests of these mixtures showed inhibitory activity, the mixtures were tested for activity in assays on Granny Smith apples. In vitro tests can be used to screen mixtures to obtain information on their inhibitory activity on a pathogen, however, the environmental conditions of the fruit and the ability of the pathogen to grow into the fruit cannot be simulated in vivo. A series of two-fold doses of medicinal plant extracts were combined with fungicides to conduct decay inhibition studies. The incidence of gray mold was significantly reduced by mixtures of plant extracts and fungicides. Under conditions similar to those in commercial storage, a drench treatment with G. africana and Rovral&trade
significantly (p=0.05) inhibit gray mold on the apples and was more effective than the plant extract and fungicide alone. The treatments exerted synergistic effects and were markedly better than the components applied alone. The wound colonization assay was used for optimal decay control. In a drench, much higher volumes of the treatments are used to ensure that the components of the suspension are deposited evenly over the entire fruit surface. Drenching of fruit to apply other chemicals is an established practise in the pome (fleshy) fruit industry, and simplifies the commercial application of the mixtures, as no additional infrastructure at commercial packing houses will be required. This approach not only makes it possible to reduce fungicide concentrations while maintaining adequate decay control, but also ensures a reduction of the chemical residue on the fruit.

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Elmestiri, Fatma M. "Evaluation of selected Libyan medicinal plant extracts for their antioxidant and anticholinesterase activities." Thesis, University of Newcastle Upon Tyne, 2007. http://hdl.handle.net/10443/615.

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In different parts of the world, the use of medicinal plants has always been important in the therapeutic armory of mankind and remains an important source for the discovery of new bio-active compounds. Libya constitutes an apt example where medicinal plants are widely used. While some individual plant species such as Ginkgo biloba have been investigated in some detail, there is relatively little information available concerning the antioxidant potential and anticholinesterase activities of plant species in general and Libyan plants in particular. In this study twenty three Libyan medicinal plants were chosen for the study of antioxidant capacity and phenolic content. Aqueous plant extracts were screened for their antioxidant activity using the FRAP, TEAC and DPPH methods. These methods enable high-throughput screening of potential antioxidant capacity. Results show that of these twenty three plants, hot and cold extracts of Myrtus communis, Quercus robur and Syzygium aromaticum exhibited the strongest antioxidant activity in all tests and this is higher than that of the green tea control. It is suggested that the efficacy of these plants could be explained, at least in part, by their antioxidant activity. A selection of ten Libyan plants which have various ethnobotanical uses were evaluated for anticholinesterase activity. Most plants screened showed some inhibitory activity with either or both acetyl- and butyrylcholinesterase. Digestion is an initial step involving changes in pH and activity of proteolytic enzymes. Plant extracts were evaluated for possible changes in antioxidant properties and anticholinesterase activity using an artificial digestion technique. Most extracts showed an increase in antioxidant activity after the final pancreatin step although results varied with the antioxidant assay used. However, almost all anticholinesterase activity was lost at the HC1 stage of the in vitro digestion procedure. Testing in vitro bioavailability of plant extracts is a useful step in evaluating in vivo bioavailability.
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Samdumu, Faga B. "Characterization of antimicrobial compounds from Combretum paniculatum, a plant with proven anti-HIV replication activity." Electronic thesis, 2007. http://upetd.up.ac.za/thesis/available/etd-08032007-173831/.

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Essack, Magbubah. "Screening extracts of indigenous South African plants for the presence of anti-cancer compounds." Thesis, University of the Western Cape, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_8767_1210844967.

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Early man dabbled with the use of plant extracts to cure ailments. This practice has been passed down from generation to generation and today more than 50% of the world'sdrugs are natural products or derivatives thereof. Scientists have thus established a branch of research called natural product research. This branch of research involves the identification and purification of secondary metabolites with a specific biological activity. The methodology involves the screening of plant products for a specific biological activity, purification of the biologically active natural product by separation technology and structure determination. The biologically active natural products is then further scrutinized to serve as a novel drug or lead compound for the development of a novel drug. This research exploited this research methodology.

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Books on the topic "Medicinal plant extracts"

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Lewington, Anna. A review of the importation of medicinal plants and plant extracts into Europe. Cambridge, U.K: TRAFFIC International, 1993.

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Medicinal plants: Chemistry and properties. Enfield, (NH): Science Publishers, 2005.

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Houghton, Peter J. Laboratory handbook for the fractionation of natural extracts. London: Chapman & Hall, 1998.

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B, Bastyr John, ed. Plant medicine in practice: Using the teachings of John Bastyr. St. Louis, Mo: Churchill Livingstone, 2003.

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Brinker, Francis J. The toxicology of botanical medicines. 2nd ed. [Portland, Ore.]: National College of Naturopathic Medicine, 1986.

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Brinker, Francis J. The toxicology of botanical medicines. 3rd ed. Sandy, Or: Electic Medical Publications, 2000.

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Brinker, Francis J. The toxicology of botanical medicines. 2nd ed. Portland, Ore: Eclectic Institute, 1989.

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Filho, Valdir Cechinel. Plant bioactives and drug discovery: Principles, practice, and perspectives. Hoboken, N.J: John Wiley & Sons, 2011.

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Hostettmann, K. Handbook of chemical and biological plant analytical methods. Chichester, West Sussex: John Wiley & Sons Inc., 2014.

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Herbal drugs: Quality & chemistry. Houston, Tex: Studium Press, 2011.

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Book chapters on the topic "Medicinal plant extracts"

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Bilal, Muhammad, Hira Munir, and Hafiz M. N. Iqbal. "Potentialities of Medicinal Plant Extracts Against Biofilm-Forming Bacteria." In Microbial Biofilms, 187–203. Boca Raton : CRC Press, 2020.: CRC Press, 2020. http://dx.doi.org/10.1201/9780367415075-12.

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Rahuman, A. Abdul. "Efficacies of Medicinal Plant Extracts Against Blood-Sucking Parasites." In Nature Helps..., 19–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-19382-8_2.

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Aqil, Farrukh, Maryam Zahin, Iqbal Ahmad, Mohd Owais, Mohd Sajjad Ahmad Khan, Shyam S. Bansal, and S. Farooq. "Antifungal Activity of Medicinal Plant Extracts and Phytocompounds: A Review." In Combating Fungal Infections, 449–84. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12173-9_19.

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Tahmasebi, Aminallah, and Akbar Karami. "Antifungal, Antimycotoxigenic, and Antioxidant Activity of Essential Oils and Medicinal Plant Extracts." In Environmental and Microbial Biotechnology, 225–38. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-7098-8_9.

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Prakash, A. O. "Biological evaluation of some medicinal plant extracts for contraceptive efficacy in females." In Future Aspects in Contraception, 115–28. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-4916-4_11.

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Gođevac, Dejan, Milka Jadranin, Ivana Aljančić, Vlatka Vajs, Vele Tešević, and Slobodan Milosavljević. "Application of Spectroscopic Methods and Hyphenated Techniques to the Analysis of Complex Plant Extracts." In Medicinal and Aromatic Plants of the World, 61–85. Dordrecht: Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-017-9810-5_4.

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Vanhaelen, M., and R. Vanhaelen-Fastré. "Thin-Layer Chromatography-Densitometry as a Powerful Method for the Standardization of Medicinal Plant Extracts." In Recent Advances in Thin-Layer Chromatography, 187–200. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4899-2221-2_20.

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Kannan, Govind, Thomas H. Terrill, Brou Kouakou, and Jung H. Lee. "Dietary Brown Seaweed Extract Supplementation in Small Ruminants." In Medicinal Plants, 291–312. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-31269-5_13.

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Sinha, Koel, and Chitrangada Das Mukhopadhyay. "Immunomodulatory Effect of Plant-Based Extracts on Neurodegeneration." In Advanced Studies in Experimental and Clinical Medicine, 31–52. Includes bibliographical references and index.: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9781003057451-3.

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López, J. L., C. Baltazar, M. Torres, A. Ruız, R. Esparza, and G. Rosas. "Biosynthesis of Silver Nanoparticles Using Extracts of Mexican Medicinal Plants." In Characterization of Metals and Alloys, 157–66. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-31694-9_13.

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Conference papers on the topic "Medicinal plant extracts"

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Tapanes-Castillo, Alexis, Dora Maul, Luis Fernandez-Torres, Maria Pina, Vadym Trokhymchuk, Andrea Peterson, and Carlos Planchart. "Evaluating medicinal plants for anticancer properties: testing plant extracts for cytotoxicity ." In MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd edition. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/mol2net-03-05095.

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Negreanu-Pirjol, Ticuta. "PHARMACEUTICAL FORMULATIONS BASED ON INDIGENE MEDICINAL PLANT EXTRACTS WITH ANTIOXIDANT ACTIVITY." In 15th International Multidisciplinary Scientific GeoConference SGEM2015. Stef92 Technology, 2015. http://dx.doi.org/10.5593/sgem2015/b61/s25.068.

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Oalđe, Mariana, Marija Mandić, Uroš Gašić, Tanja Lunić, Stoimir Kolarević, Branka Vuković-Gačić, Ana Alimpić Aradski, Petar Marin, Biljana Božić Nedeljković, and Sonja Duletić-Laušević. "Chemical characterization of Lamiaceae plant extracts – the quest for novel immunomodulators." In 6th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07280.

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Bruguière, A., S. Derbré, J. Dietsch, J. Leguy, V. Rahier, Q. Pottier, F. Saubion, and P. Richomme. "13C-NMR dereplication of medicinal plant extracts using a home-made software." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399821.

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Seephonkai, P., N. Mongkolsiri, W. Thiabphet, S. Sedlak, K. Wongpakam, and A. Sangdee. "Antioxidant and antibacterial activities of selected Thai medicinal plant-derived Galactogogue extracts." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399855.

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Mladenovic, Jelena, Veronika Markovic, Ljiljana Boskovic-Rakocevic, Milena Đuric, and Nenad Pavlovic. "ISPITIVANJE EKSTRAKATA ORIGANA DOBIJENIH RAZLIČITIM METODAMA." In XXVI savetovanje o biotehnologiji sa međunarodnim učešćem. University of Kragujevac, Faculty of Agronomy, 2021. http://dx.doi.org/10.46793/sbt26.407m.

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Oregano is used in the production of specific aromatic cheeses, meat products and dough dishes, for the production of medicinal preparations, fragrant soaps, colognes and perfumes. Special interest in oregano in recent years is related to the results of a study of its biological activities, which indicate a wide range of antibacterial, fungicidal, antiviral and antioxidant properties. The subject of this paper is the examination of extracts of plant species of oregano (Origanum vulgare), with the aim of determining the method that is most popular for extracting this plant species and which gives the best yields of extracts. The content of extracted substances in each extract, the content of vitamin C as well as the content of organic acids were determined.
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ULRICH, Elena. "Study of Quality and Safety Parameters of Phytobiotics Based on Medicinal Plant Extracts." In Current Trends of Agricultural Industry in Global Economy. SibAC, 2021. http://dx.doi.org/10.32743/agri.gl.econ.2020.258-264.

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Skorbach, Valentina, and Yulia Kurkina. "Influence of Medicinal Plant Extracts on the Number of Columns of Strain Escherichia Coli." In Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019). Paris, France: Atlantis Press, 2019. http://dx.doi.org/10.2991/isils-19.2019.71.

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Iancu, Irina Mihaela, Laura Adriana Bucur, Verginica Schröder, and Manuela Rossemary Apetroaei. "TESTING THE BIOLOGICAL ACTIVITY OF LYTHRI HERBA EXTRACT FOR APPLICATIONS IN MEDICAL BIOTECHNOLOGIES." In GEOLINKS Conference Proceedings. Saima Consult Ltd, 2021. http://dx.doi.org/10.32008/geolinks2021/b1/v3/26.

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"Nowadays we are witnessing an increased interest in phytotherapy and implicitly for herbal products that have lower side effects. One medicinal plant whose popularity has decreased significantly in recent years is Lythrum salicaria L., loosestrife, known in Romanian traditional medicine for its beneficial effects against gastrointestinal diseases. The aim of this study is to evaluate the biological activity of three different extracts (aqueous, alcoholic, acetonic) from the flower tips of Lythrum salicaria L. using the BSLA (Brine Shrimp Lethality Assay) test and the antimicrobial activity of the extracts on two reference bacterial strains which are important for the medical field (Staphylococcus aureus and Escherichia coli) through the diffusimetric method. We demonstrated the fact that the Lythri herba plant product extracts (aqueous, alcoholic, and acetonic) lack acute toxicity, as well as the moderate antibacterial effect on the Gram-positive reference strain, Staphylococcus aureus, thus highlighting the possibility of using the plant in biomedical applications."
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Tanvir, Rabia, Hafsa Shahzadi, Ali Ahmad Sheikh, and Wasim Shehzad. "Comparison of the bioactivity of tulsi and neem plant extracts with their related endophytic actinomycetes against ESBL producers." In 6th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07262.

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