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1

Saranya, K., V. Manivasagan, K. Gopi, and K. Karthik. "Broad-spectrum survey of medicinal plants as a potential source of anticancer agents." Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas 21, no. 1 (2022): 1–40. http://dx.doi.org/10.37360/blacpma.22.21.1.01.

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Cancer is an abnormal and uncontrolled growth of cells that spreads through cell division. There are different types of medicines available to treat cancers, but no drug is found to be fully effective and safe for humans. The major problem involved in the cancer treatments is the toxicity of the established drug and their side effects. Medicinal plants are used as folk medicines in Asian and African populations for thousands of years. 60% of the drugs for treating cancer are derived from plants. More than 3000 plants have anticancer activity. The present review aims at the study of a broad spe
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Gbeassor, M., Y. Kossou, K. Amegbo, C. De Souza, K. Koumaglo, and A. Denke. "Antimalarial effects of eight african medicinal plants." Journal of Ethnopharmacology 25, no. 1 (1989): 115–18. http://dx.doi.org/10.1016/0378-8741(89)90051-2.

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Maher, Tahani, Raha Ahmad Raus, Djabir Daddiouaissa, et al. "Medicinal Plants with Anti-Leukemic Effects: A Review." Molecules 26, no. 9 (2021): 2741. http://dx.doi.org/10.3390/molecules26092741.

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Leukemia is a leukocyte cancer that is characterized by anarchic growth of immature immune cells in the bone marrow, blood and spleen. There are many forms of leukemia, and the best course of therapy and the chance of a patient’s survival depend on the type of leukemic disease. Different forms of drugs have been used to treat leukemia. Due to the adverse effects associated with such therapies and drug resistance, the search for safer and more effective drugs remains one of the most challenging areas of research. Thus, new therapeutic approaches are important to improving outcomes. Almost half
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4

Setorki, Mahbubeh. "Medicinal herbs with anti-depressant effects." Journal of Herbmed Pharmacology 9, no. 4 (2020): 309–17. http://dx.doi.org/10.34172/jhp.2020.39.

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Depression is a life-threatening chronic illness which affects people worldwide. Drugs used to treat this disease have multiple side effects and may cause drug-drug or drug-food interactions. Additionally, only 30% of patients respond adequately to the existing drugs and the remaining do not achieve complete recovery. Thus, finding effective treatments that have adequate efficacy, fewer side effects and lower cost seem to be necessary. The purpose of this study was to review animal and double-blind clinical studies on the anti-depressant effects of medicinal herbs. In this study, validated sci
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Chhipa, Abu Sufiyan, and S. S. Sisodia. "Indian Medicinal Plants with Antidiabetic Potential." Journal of Drug Delivery and Therapeutics 9, no. 1 (2019): 257–65. http://dx.doi.org/10.22270/jddt.v9i1.2282.

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Medicinal plants should be evaluated extensively to determine the active principles present in them that are responsible for the hypoglycemic activity of these plants. Herbal drugs have gained popularity among the general population due to their ability to treat ailments with minimum side effects. The multi-target approaches of medicinal plants make them least susceptible to failure during the treatment therapy. Medicinal plants showing prominent anti-diabetic activity during the initial studies should be further explored to identify the active principles present in them that can become the pr
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Ojetunde, A. O. "ANTIDIABETIC EFFECTS OF MEDICINAL PLANTS." Eastern Ukrainian Medical Journal 9, no. 1 (2021): 1–17. http://dx.doi.org/10.21272/eumj.2021;9(1):1-17.

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Diabetes is a chronic disorder that is characterized by an increase in blood glucose (hyperglycemia) with alteration of protein, carbohydrates, and fat metabolism. Consequently, it can lead to renal failure, atherosclerosis, nerve damage, blindness, and coronary heart disease. It is also known as the 5th leading cause of death. Although, there are numerous types of glucose-lowering drugs that exhibit anti-diabetic effects but results of treatment in patients are still not so perfect. Therefore, many treatments that include the use of medicinal plants are suggested and encouraged. Medical plant
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Ilhan, Mert, Fatma Tuğçe Gürağaç Dereli, and Esra Küpeli Akkol. "Novel Drug Targets with Traditional Herbal Medicines for Overcoming Endometriosis." Current Drug Delivery 16, no. 5 (2019): 386–99. http://dx.doi.org/10.2174/1567201816666181227112421.

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Endometriosis is a disease in which the lining of the endometrium is found outside of the uterus. Recent medical treatments for endometriosis have adverse effects, limiting their long-term use. Furthermore, the recurrence of the disease after the cessation of therapy is quite common, and most patients need to continue treatment to maintain a hypoestrogenic environment till conception. Notwithstanding recent advances in computational and chemical practices, traditional medicines are considered the most consistent sources for the discovery of new drugs. Numerous medicinal plants and plantderived
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Shen, Yu-Li, Xiao-Qin Li, Rong-Rong Pan, Wei Yue, Li-Jun Zhang, and Hong Zhang. "Medicinal Plants for the Treatment of Hair Loss and the Suggested Mechanisms." Current Pharmaceutical Design 24, no. 26 (2018): 3090–100. http://dx.doi.org/10.2174/1381612824666180911114810.

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Hair loss may not be recognized as a life-threatening disorder. However, it has a great harm to a person’s self-respect, mental health, and entirety quality of life. Androgenic alopecia (AGA) is the most common type of hair loss, which affects a great number of both men and women. Alopecia can be treated with various hair loss strategies, including hair transplant, cosmetics and medication. Medical treatment shows the outstanding ability in improving hair growth. Plenty of drugs prevents alopecia by inhibiting the secretion of male hormone. But these medicines exhibit some undesirable side eff
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9

Mustafa, Sodah Bint, Muhammad Akram, Hafiz Muhammad Asif, et al. "Antihyperglycemic Activity of Hydroalcoholic Extracts of Selective Medicinal Plants Curcuma longa, Lavandula stoechas, Aegle marmelos, and Glycyrrhiza glabra and Their Polyherbal Preparation in Alloxan-Induced Diabetic Mice." Dose-Response 17, no. 2 (2019): 155932581985250. http://dx.doi.org/10.1177/1559325819852503.

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Background: Diabetes mellitus is a metabolic disorder associated with relative or absolute insulin deficiency or resistance, characterized by hyperglycemia. Modern prescriptions such as pioglitazone have better therapeutic potential, but its side effects and financial burden for developing countries have motivated the researchers to find alternative natural drugs to compete hyperglycemia in patients with diabetes. The present study was conducted to explore the therapeutic potential of selected medicinal plants for the treatment of diabetes as an alternative to allopathic medicines. Method: In
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10

Ghanadi, Koroush, Afshin Hasanvand, Saber Abbaszadeh, Saeid Heidari-Soureshjani, and Tahra Suhan. "Phytotherapy: An anti-hepatotoxicity and hepatoprotective approach in chemotherapy." Plant Science Today 6, no. 2 (2019): 114–22. http://dx.doi.org/10.14719/pst.2019.6.2.514.

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Chemotherapy induced-hepatotoxicity is one of the prevalent problems among cancer patients, with a wide spectrum of complications from liver dysfunction to liver necrosis. Therefore, in this study, we review the research findings on the effects of medicinal herbs and herbal compounds on the hepatotoxicity induced by anticancer drugs. The words hepatotoxicity and hepatoprotective along with the words cancer drug or chemotherapy in combination with some herbal terms such as medicinal plant, phyto* and herb* were used to search for relevant publications indexed in the Institute for Scientific Inf
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Bahmani, Mahmoud, Mahmoud Mirhoseini, Hedayatollah Shirzad, Mehrnoosh Sedighi, Nejmeh Shahinfard, and Mahmoud Rafieian-Kopaei. "A Review on Promising Natural Agents Effective on Hyperlipidemia." Journal of Evidence-Based Complementary & Alternative Medicine 20, no. 3 (2015): 228–38. http://dx.doi.org/10.1177/2156587214568457.

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Hyperlipidemia is a prevalent disease and a major component of the metabolic syndrome resulting from various factors. This disease increases morbidity and mortality when combined with other prevalent diseases such as diabetes mellitus, hypertension, and cardiovascular diseases. The side effects of the current lipid-lowering drugs have increased the tendency to move toward traditional and alternative treatments. Epidemiological observations indicate that using alternative treatments, consumption of medicinal plants, diet, and consumption of fruits have had satisfactory results on the effects of
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Jacobo-Salcedo, Maria del Rosario, Angel Josabad Alonso-Castro, Luis A. Salazar-Olivo, et al. "Antimicrobial and Cytotoxic Effects of Mexican Medicinal Plants." Natural Product Communications 6, no. 12 (2011): 1934578X1100601. http://dx.doi.org/10.1177/1934578x1100601234.

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The antimicrobial effects of the Mexican medicinal plants Guazuma ulmifolia, Justicia spicigera, Opuntia joconostle, O. leucotricha, Parkinsonia aculeata, Phoradendron longifolium, P. serotinum, Psittacanthus calyculatus, Tecoma stans and Teucrium cubense were tested against several human multi-drug resistant pathogens, including three Gram (+) and five Gram (-) bacterial species and three fungal species using the disk-diffusion assay. The cytotoxicity of plant extracts on human cancer cell lines and human normal non-cancerous cells was also evaluated using the MTT assay. Phoradendron longifol
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Yesilada, E. "Novel drug leads from Turtkish medicinal plants with diverse pharmacological effects." Drugs of the Future 33, no. 8 (2008): 673. http://dx.doi.org/10.1358/dof.2008.033.08.1220137.

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Lam, Kit Ying, Anna Pick Kiong Ling, Rhun Yian Koh, Ying Pei Wong, and Yee How Say. "A Review on Medicinal Properties of Orientin." Advances in Pharmacological Sciences 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/4104595.

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Medicinal plants continue to play an important role in modern medications and healthcare as consumers generally believe that most of them cause fewer or milder adverse effects than the conventional modern medicines. In order to use the plants as a source of medicinal agents, the bioactive compounds are usually extracted from plants. Therefore, the extraction of bioactive compounds from medicinal plants is a crucial step in producing plant-derived drugs. One of the bioactive compounds isolable from medicinal plants, orientin, is often used in various bioactivity studies due to its extensive ben
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Hussain, Kashif, Rao Zahid Abbas, Asghar Abbas, et al. "Therapeutic potential of medicinal plants against Leishmaniasis: a public health concern." Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas 20, no. 2 (2021): 123–31. http://dx.doi.org/10.37360/blacpma.21.20.2.10.

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Leishmaniasis is an important disease affecting global public health which is spread by sand fly having different species. Various chemical drugs are used to treat and control Leishmaniasis including pentavalent antimonials, antimicrobial and antibiotics. Due to emergence of drug resistance, these therapeutic options are losing effectiveness in attaining success. Furthermore, these drugs are expensive and have toxic effects on liver and kidneys. There has been an emerging interest and excellent response by using plant based drugs and extracts to control Leishmaniasis. Different medicinal plant
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Maqbool, Mudasir, Imran Gani, and Mohmad Amin Dar. "ANTI-DIABETIC EFFECTS OF SOME MEDICINAL PLANTS IN EXPERIMENTAL ANIMALS: A REVIEW." Asian Journal of Pharmaceutical Research and Development 7, no. 1 (2019): 66–69. http://dx.doi.org/10.22270/ajprd.v7i1.469.

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Diabetes is a chronic endocrine disease with global prevalence and increasing incidence. Diabetes presents with a major health issue in all age groups in the present times owing to its multisystem involvement and serious complications. In spite of drug development and therapeutic interventions, successful treatment of diabetes still remains a challenge and worldwide research is focused on finding alternative modalities. By conducting sizable amount of analytical work, numerous traditional medicines have been found for diabetes. Substances and extracts isolated from completely different natural
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17

Sanusi, Shuaibu Babaji, Mohd Fadzelly Abu Bakar, Maryati Mohamed, Siti Fatimah Sabran, and Muhammad Murtala Mainasara. "Southeast Asian Medicinal Plants as a Potential Source of Antituberculosis Agent." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–39. http://dx.doi.org/10.1155/2017/7185649.

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Despite all of the control strategies, tuberculosis (TB) is still a major cause of death globally and one-third of the world’s population is infected with TB. The drugs used for TB treatment have drawbacks of causing adverse side effects and emergence of resistance strains. Plant-derived medicines have since been used in traditional medical system for the treatment of numerous ailments worldwide. There were nine major review publications on antimycobacteria from plants in the last 17 years. However, none is focused on Southeast Asian medicinal plants. Hence, this review is aimed at highlightin
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18

Chomnawang, Mullika Traidej, Suvimol Surassmo, Veena S. Nukoolkarn, and Wandee Gritsanapan. "Antimicrobial effects of Thai medicinal plants against acne-inducing bacteria." Journal of Ethnopharmacology 101, no. 1-3 (2005): 330–33. http://dx.doi.org/10.1016/j.jep.2005.04.038.

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19

Arefin, Paroma, Md Shehan Habib, Aishawarya Arefin, and Md Saidul Arefin. "Determination of potential sources of drug development for menstrual disorders: A qualitative analysis of published literature of in-vitro rat uterus experimental studies." International Journal of Pharmaceutical Chemistry and Analysis 8, no. 2 (2021): 45–48. http://dx.doi.org/10.18231/j.ijpca.2021.010.

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Many herbal plants have been recorded in medicine for their usefulness in menstrual disorders, however, a few have been extensively examined for their pharmacological activities. These plants have been recorded to have usefulness in the management of painful menses, preventing miscarriages, prolonging birth, or inducing birth. Therefore, the effects of herbal plants on the contractility of the uterus will be investigated using the in-vitro experiment of the isolated rat uterus. The study aims to assess the most outstanding plants that are used to treat menstrual disorders, their uterine contra
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Daoudi, Nour Elhouda, Mohamed Bouhrim, Hayat Ouassou, and Mohamed Bnouham. "Medicinal Plants as a Drug Alternative Source for the Antigout Therapy in Morocco." Scientifica 2020 (November 23, 2020): 1–10. http://dx.doi.org/10.1155/2020/8637583.

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Background. The gout is a metabolic disease that is associated with a high level of uric acid in the blood. This disease is treated with some medications that aim to reduce serum urate levels. However, the use of various medicines leads to the appearance of some side effects, hence the importance of using other treatments based on natural resources. Objective. This study presents some medical treatments, their side effects, and some plants that are used for gout management in Morocco in the aim to valorize them. Methods. We have been consulting various English publications in PubMed, Web of Sc
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Chakraborty, Tania, and Santanu Paul. "Glinus oppositifolius (L.) Aug. DC.: A Repository of Medicinal Potentiality." International Journal of Phytomedicine 9, no. 4 (2017): 543. http://dx.doi.org/10.5138/09750185.2164.

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<p>Plants have been used in the treatment of human diseases since centuries. Due to their medicinal values, more than 80% of the modern world population still rely on plants as their primary source of medicines. Traditional plant-based medicines are widespread in Asian countries like the Indian subcontinent, Bangladesh, China, Japan, Pakistan, Indonesia, Myanmar, and in the continent of Africa. Nowadays, plant-derived medicines are gaining wider acceptance even in developed countries of the Western world. More than 50% of all drugs currently in clinical use are of natural origin. Plants
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Dereli, Fatma Tuğçe Gürağaç, Mert Ilhan, and Esra Küpeli Akkol. "New Drug Discovery from Medicinal Plants and Phytoconstituents for Depressive Disorders." CNS & Neurological Disorders - Drug Targets 18, no. 2 (2019): 92–102. http://dx.doi.org/10.2174/1871527317666181114141129.

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Background & Objective: Depression, a risk factor for several serious diseases, is a highly prevalent and life-threatening psychiatric disorder. It can affect the individual’s position in life and reduce the living standards. The research on the use of medicinal plants in treating this disease has increased enormously because of the possible low rehabilitation rate and side effects of available synthetic drugs, such as sexual dysfunction, nausea, fatigue, insomnia, hypersomnia, and weight gain.Conclusion:Therefore, this review aimed to draw attention to the antidepressant effects of culina
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Teodor, Eugenia Dumitra, Veronica Moroeanu, and Gabriel Lucian Radu. "Lignans from Medicinal Plants and their Anticancer Effect." Mini-Reviews in Medicinal Chemistry 20, no. 12 (2020): 1083–90. http://dx.doi.org/10.2174/1389557520666200212110513.

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Since early times, various plants have been used as remedies for treating different kinds of diseases and lesions with satisfying results. The phenolic compounds are secondary metabolites from medicinal plants which include a wide category of compounds such as phenolic acids, flavonoids, tannins, stilbenes, curcuminoids, xanthones, coumarins, lignans, etc. Between these, lignans are considered important in cancer prevention and treatment, besides other beneficial health effects, e.g. antioxidant, anticarcinogenic, antimutagenic, and anti-estrogenic effects. This review summarizes the most rece
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Ashwlayan, Dr Vrish Dhwaj, and Saurabh Nimesh. "Cutting Edge of Herbal Drugs over Allopathic Drugs in Clinical Treatment of Rheumatoid Arthritis." Journal of Bone Biology and Osteoporosis 4, no. 1 (2018): 43–50. http://dx.doi.org/10.18314/jbo.v4i1.1194.

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Rheumatoid arthritis (RA) is a chronic inflammatory and systemic auto immune disease, affecting people predominantly between the ages of 20-60 years with unpredictable course. About 1% of the world's population is afflicted by rheumatoid arthritis and is two to three times more common in women than men. This is a long lasting disease that can affect joints in any part of the body, most commonly the hands, wrists, and knees. Popularity of medicinal plants is increasing day by day due to side effects of allopathic medicines. Herbal medicinal plants have been used as major sources of cure of huma
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Davoodvandi, Amirhossein, Roxana Sahebnasagh, Omid Mardanshah, et al. "Medicinal Plants As Natural Polarizers of Macrophages: Phytochemicals and Pharmacological Effects." Current Pharmaceutical Design 25, no. 30 (2019): 3225–38. http://dx.doi.org/10.2174/1381612825666190829154934.

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Macrophages are one of the crucial mediators of the immune response in different physiological and pathological conditions. These cells have critical functions in the inflammation mechanisms that are involved in the inhibition or progression of a wide range of diseases including cancer, autoimmune diseases, etc. It has been shown that macrophages are generally divided into two subtypes, M1 and M2, which are distinguished on the basis of their different gene expression patterns and phenotype. M1 macrophages are known as pro-inflammatory cells and are involved in inflammatory mechanisms, whereas
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Mulat, Mulugeta, Fazlurrahman Khan, Gizachew Muluneh, and Archana Pandita. "Phytochemical Profile and Antimicrobial Effects of Different Medicinal Plant: Current Knowledge and Future Perspectives." Current Traditional Medicine 6, no. 1 (2020): 24–42. http://dx.doi.org/10.2174/2215083805666190730151118.

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The application of medicinal plants for combating various human ailments, as a food fortificant and additive have been adapted from ancient routine custom. Currently, developing countries use plants as a major source of primary health care. Besides, the emerging drug resistant pathogenic microbes encourage the utilization of medicinal plants as preeminent alternative sources of new bioactive substances. Extensive research findings have been reported in the last three decades. But methods to investigate the phytoconstituent and their biological effects are limited. This review contains brief ex
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Ismail, Hammad, Muhammad Ammar Amanat, Adnan Iqbal, and Bushra Mirza. "Medicinal Plants: A Complementary and Alternative Antidepressant Therapy." Current Pharmaceutical Design 24, no. 22 (2018): 2609–24. http://dx.doi.org/10.2174/1381612824666180727123950.

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There is enough data available now to believe that nature has provided cure of almost every ailment through herbal medicine or management. Therefore, now there is lot of emphasis on identification, evaluation, development and characterization of numerous plants and their active constituents against several diseases including depression. Depression is not only one of the most common ailments but also a highly complex condition to study. Even though several antidepressant drugs are available now, yet their effectiveness and usefulness are highly questionable especially because of their side effe
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Okaiyeto, Kunle, and Oluwafemi O. Oguntibeju. "African Herbal Medicines: Adverse Effects and Cytotoxic Potentials with Different Therapeutic Applications." International Journal of Environmental Research and Public Health 18, no. 11 (2021): 5988. http://dx.doi.org/10.3390/ijerph18115988.

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The African continent is naturally endowed with various plant species with nutritional and medicinal benefits. About 80% of the people in developing countries rely on folk medicines to treat different diseases because of indigenous knowledge, availability, and cost-effectiveness. Extensive research studies have been conducted on the medicinal uses of African plants, however, the therapeutic potentials of some of these plants has remained unexploited. Over the years, several studies have revealed that some of these African floras are promising candidates for the development of novel drugs. Desp
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Abouzekry, Sara S., Marwa T. Badawy, Nada M. Ezzelarab, and Ahmed Abdellatif. "Phytotherapy for diabetes mellitus; A review of Middle Eastern and North African folk medicinal plants." Journal of Herbmed Pharmacology 10, no. 1 (2020): 1–13. http://dx.doi.org/10.34172/jhp.2021.01.

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Diabetes mellitus (DM) is considered as one of the most common metabolic disorders affecting huge number of people worldwide. Despite the availability of large numbers of drugs in the market to treat the disease, there is still a need for new sources to deal with the problem and avoid side effects. In the pursuit of discovering safer and more effective anti-diabetic drugs, herbal and folk medicine drugs from regions all over the world have captured researchers’ interest. Middle Eastern and North African medicinal plants contain a variety of pharmacologically active components that have shown t
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Saktiawan, Renny Agus, and Atmiasri Atmiasri. "PEMANFAATAN TANAMAN TOGA BAGI KESEHATAN KELUARGA DAN MASYARAKAT." Jurnal Abadimas Adi Buana 1, no. 2 (2017): 57–64. http://dx.doi.org/10.36456/abadimas.v1.i2.a960.

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ABSTRACT
 
 Medicinal plants are a source of power that has existed since age-old. TOGA used by our ancestors in order to overcome health problems by making various ingredients of medicinal issues. Therefore the use of medicinal plant families or we called TOGA should be developed and circulated in the community, especially for all of households. But many people are still not aware of the utilization of family medicine. People often mistake them for the raw material too produce of traditional medicines and they do not understand yet how to process the material. It can cause side effe
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Khan, Ishfaq, and Azhar Khan. "MEDICINAL PLANTS AS ALTERNATIVE TREATMENTS FOR ORAL HEALTH PROBLEMS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 9 (2018): 58. http://dx.doi.org/10.22159/ajpcr.2018.v11i9.24918.

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Oral flora plays an important role in the day-to-day life for human beings and also they are important part of human digestive system. Simultaneously, besides their beneficial activities, they can be harmful to the human, and this can be evaluated as normal oral flora as opportunistic pathogens. To elevate oral sanitation, medicinal plant-based mouthwash can be used as mediator and acts as a part of efficient home care medication. In dentistry, the importance of plants has been acknowledged to cure diseases generated by several oral pathogens. Chemical drugs possess many side effects and act a
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Kumar, Ajay, Feroz Khan, and Dharmendra Saikia. "Exploration of Medicinal Plants as Sources of Novel Anticandidal Drugs." Current Topics in Medicinal Chemistry 19, no. 28 (2019): 2579–92. http://dx.doi.org/10.2174/1568026619666191025155856.

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Background: : Human infections associated with skin and mucosal surfaces, mainly in tropical and sub-tropical parts of the world. During the last decade, there have been an increasing numbers of cases of fungal infections in immunocompromised patients, coupled with an increase in the number of incidences of drug resistance and toxicity to anti fungal agents. Hence, there is a dire need for safe, potent and affordable new antifungal drugs for the efficient management of candidal infections with minimum or no side effects. Introduction: : Candidiasis represents a critical problem to human health
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Okaiyeto, Kunle, UchechukwuU Nwodo, LeonardV Mabinya, and AnthonyI Okoh. "A review on some medicinal plants with hepatoprotective effects." Pharmacognosy Reviews 12, no. 24 (2018): 186. http://dx.doi.org/10.4103/phrev.phrev_52_17.

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Khosravian, Pegah, Saeid Heidari-Soureshjani, and Qian Yang. "Effects of medicinal plants on radiolabeling and biodistribution of diagnostic radiopharmaceuticals: A systematic review." Plant Science Today 6, no. 2 (2019): 123–31. http://dx.doi.org/10.14719/pst.2019.6.2.513.

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Radiopharmaceuticals are drugs that contain radioisotopes used for diagnostic and therapeutic purposes. There are evidences that medicinal herbs and their constituents can modify the radiolabeling, biodistribution, and pharmacokinetics of radiopharmaceuticals through drug interaction. To have an overview of the effects and the underlying mechanisms of medicinal plants on the radiolabeling and bioavailability of radiopharmaceuticals, we conducted this study to summarize the current findings in this field. The scientific literature was systematically collected from databases and analyzed. Studie
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Lin, Chun-Ching, and Woei-Song Kan. "Medicinal Plants Used for the Treatment of Hepatitis in Taiwan." American Journal of Chinese Medicine 18, no. 01n02 (1990): 35–43. http://dx.doi.org/10.1142/s0192415x9000006x.

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In an extensive ethnobotanical survey of the folk medicines of Taiwan, 69 kinds of crude drugs and 107 species of medicinal plants were found to be used for hepatitis treatments. The present paper is to update a list of medicinal plants used in the treatment of hepatitis and evaluate their liver protection by ethnopharmacological and pathological studies. Results show that some of these drugs have prominent therapeutic effects. Further investigation regarding the anti-hepatotoxic principles will be made.
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Megersa, Moa, Tilahun Tolossa Jima, and Kabaye Kumela Goro. "The Use of Medicinal Plants for the Treatment of Toothache in Ethiopia." Evidence-Based Complementary and Alternative Medicine 2019 (August 20, 2019): 1–16. http://dx.doi.org/10.1155/2019/2645174.

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This paper presents a review of relevant medicinal plants used for toothache treatment in Ethiopia. This finding is based on a review of the literature published in scientific journals. A total of 130 medicinal plants, distributed in 117 genera and 62 families, are reported in the reviewed literature. Of the 130 species of medicinal plants reported in the literature, ninety-two (70.7%) were obtained from the wild whereas twelve (9.2%) were from home gardens. Shrubs (34.6%) were the primary source of medicinal plants, followed by herbs (30%). The Asteraceae came out as a leading family with 12
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Sedighi, Mehrnoosh, Robert D. E. Sewell, Afshin Nazari, et al. "A Review on the Most Important Medicinal Plants Effective in Cardiac Ischemia-Reperfusion Injury." Current Pharmaceutical Design 25, no. 3 (2019): 352–58. http://dx.doi.org/10.2174/1381612825666190329144016.

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: Ischemia, referring to reduction and restriction of perfusion to myocardial tissue which involves coronary artery through the formation of misplaced clots and thrombosis, is one of the most important cardiovascular diseases. Plant-based compounds help to improve or prevent disease by affecting the factors involved in the disease. This review was conducted to report the medicinal plants and factors effective in cardiac ischemiareperfusion (I/R) injury to supplement the knowledge about this disease and its prevention and treatment using certain medicinal plants and their active compounds. For
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Gholipour, Sajedeh, Robert D. E. Sewell, Zahra Lorigooini, and Mahmoud Rafieian-Kopaei. "Medicinal Plants and Atherosclerosis: A Review on Molecular Aspects." Current Pharmaceutical Design 24, no. 26 (2018): 3123–31. http://dx.doi.org/10.2174/1381612824666180911121525.

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Atherosclerosis is an inflammatory vascular disease that is characterized by progressive accumulation of cholesterol in the arterial walls and it is a major cause of cardiovascular disease. Issues related to the side effects of synthetic drugs have in recent times, led to the misuse of drugs, a lack of patient consultations, and consequently, a disruption in meticulous disease control. Therefore, a new insight into medicinal plants has recently emerged and much research has been conducted on these herbs in an attempt to prepare novel naturally based drugs. The aim of this review article was to
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Gupta, K. K., G. Khandelwal, G. Prasad, A. K. Chopra, and A. Mishra. "A review on scientific technologies in practice to innovate plant based molecules and to improve herbal drug quality to overcome health problems." Journal of Applied and Natural Science 2, no. 1 (2010): 165–81. http://dx.doi.org/10.31018/jans.v2i1.116.

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Medicines obtained from drug plants and other sources are commonly called traditional medicines. They have played an important role in the treatment of several human diseases since ancient times. India possessed a great wealth of traditional health care system known as Ayurveda related to the use of plant species. The global market of herbal drugs has a great potential around the world. Demand of plant based medicines is also increasing among western countries because of a general consideration that most allopathic drugs are associated with more or less side effects. Many pharmaceutical compan
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Bahmani, Mahmoud, Naser Abbasi, Masih Hosseini, and Mahmoud Rafieian-Kopaei. "Concise review: Medicinal plants are effective against leishmaniasis." Biomedical Research and Therapy 4, no. 11 (2017): 1775. http://dx.doi.org/10.15419/bmrat.v4i11.383.

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Leishmaniasis is an important zoonotic parasitic disease in tropical areas. It is a neglected disease and is a great health catastrophe in Iran. Pentavalent antimony compounds are used for its treatment, but they have adverse effects. Therefore, the use of natural herbs with low adverse effects seems necessary for treatment of Leishmaniasis. In this study, we tried to introduce the natural medicines effective against Leishmaniasis. In this review study, keywords searched included natural medicines, herbal medicines, medicinal plants, Leishmaniasis, and treatment in relevant publications publis
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Khattak, Somia, Saeed-ur-Rehman, Hamid Ullah Shah, Waqar Ahmad, and Manzoor Ahmad. "Biological effects of indigenous medicinal plants Curcuma longa and Alpinia galanga." Fitoterapia 76, no. 2 (2005): 254–57. http://dx.doi.org/10.1016/j.fitote.2004.12.012.

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Ngamrojanavanich, Nattaya, Srinual Manakit, Surachai Pornpakakul, and Amorn Petsom. "Inhibitory effects of selected Thai medicinal plants on Na+,K+-ATPase." Fitoterapia 77, no. 6 (2006): 481–83. http://dx.doi.org/10.1016/j.fitote.2006.06.003.

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Vetriselvan Subramaniyan, Saminathan Kayarohanam, Ashok Kumar J, and Vinoth Kumarasamy. "Impact of herbal drugs and its clinical application." International Journal of Research in Pharmaceutical Sciences 10, no. 2 (2019): 1340–45. http://dx.doi.org/10.26452/ijrps.v10i2.537.

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Since ancient times until now exploring the importance of herbal medicines to treat the variety of diseases. Currently the herbal medicines searching for health, wellness and aim to achieve effective treatment without much side effect. Recent days the impact of herbal medicines well established even herbal treatment is one of the alternative medicines for most of the diseases such as hyperlipidemia, diabetes mellitus etc. Medicinal plants always have been rich sources of bioactive compounds, and that will be very helpful to human health. The reasons for herbal medicines attracted by the health
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Ebrahimi, Fatemeh, Mohammadali Torbati, Javad Mahmoudi, and Hadi Valizadeh. "Medicinal Plants as Potential Hemostatic Agents." Journal of Pharmacy & Pharmaceutical Sciences 23, no. 1 (2020): 10–23. http://dx.doi.org/10.18433/jpps30446.

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Purpose: Medicinal plants with a variety of phytochemical ingredients remain a potential source for new drug discovery. The use of medicinal herbs in a wide range of diseases and symptoms, such as bleeding, is prevalent in traditional and ethno medicine worldwide. Thus, this work provides a comprehensive review of medicinal plants or their isolated compounds, with respect to their ethno-medicinal use, which have demonstrated the stimulating effect on the hemostasis process. Methods: The relevant studies were withdrawn from electronic databases including Pubmed, EMBASE and Web of Science with a
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Majeed, Wafa, Tanweer Khaliq, Bilal Aslam, Junaid Ali Khan, and Asra Iftikhar. "Medicinal plants with gastroprotective potential." Bangladesh Journal of Pharmacology 10, no. 3 (2015): 588. http://dx.doi.org/10.3329/bjp.v10i3.23578.

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<p class="Abstract">Peptic ulcer disease (PUD) is a main source of morbidity and mortality worldwide. It is characterized by erosions in mucosal linings of stomach and duodenum. Non-steroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori are mainly responsible for peptic ulcer disease. Histamine receptor blockers and proton pump inhibitors are most prominent therapies in the treatment of peptic ulcer. However, severe adverse effects of NSAIDs have been reported. Therefore, focus is now diverted towards herbal formulations of medicinal plants for the treatment of ulcer. Plants
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Panda, Subhamay, and Leena Kumari. "Anti-Ophidian Properties of Herbal Medicinal Plants: Could it be a Remedy for Snake Bite Envenomation?" Current Drug Discovery Technologies 16, no. 4 (2019): 319–29. http://dx.doi.org/10.2174/1570163815666180718095655.

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Snake bite envenoming causes high rates of morbidity and mortality and is one of the serious health-related concerns all over the globe. Around 3200 species of snakes have been discovered till date. Amid these species, about 1300 species of snakes are venomous. On account of its severity, World Health Organization (WHO) recently included snakebite envenoming in the list of neglected tropical diseases. Immunotherapy has partially solved the issues related to snakebite envenomation. However, it is associated with numerous adverse effects, due to which alternative treatment strategies are require
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Abbaszadeh, Saber, Parisa Arvin, and Mojtaba Khaksarian. "Neuroscience and herbal plants: A review on the most important herbal plants effective on chronic pain." Plant Science Today 6, no. 4 (2019): 383–88. http://dx.doi.org/10.14719/pst.2019.6.4.572.

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Chronic pain can be periodic, persistent, or even a combination of both. Unlike acute pain, chronic pain is not usually useful, reduces the quality of life and functional abilities and also weakens mental health, interpersonal relationships, and financial status, leading to changes in appetite, sleep disorders, psychomotor retardation, tiredness and depression. Human being has always faced various kinds of pain during life and sought to relieve his pain. Pain is a sign of a disease that acts as a warning mechanism and informs of a tissue injury. In this regard, the analgesic effects of many me
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Venieraki, A., M. Dimou, and P. Katinakis. "Endophytic fungi residing in medicinal plants have the ability to produce the same or similar pharmacologically active secondary metabolites as their hosts." Hellenic Plant Protection Journal 10, no. 2 (2017): 51–66. http://dx.doi.org/10.1515/hppj-2017-0006.

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SummaryMedicinal plants have been used for thousands of years in folk medicines and still are used for their health benefits. In our days medicinal plants are exploited for the isolation of plant-derived drugs as they are very effective and have relatively less or no side effects. However, the natural resources of medicinal plants are gradually exhausted and access to plant bioactive compounds is challenged by the low levels at which these products accumulate in native medicinal plants. For instance, to meet the market demands of 3 Kg per year of vinca alkaloids, powerful plant-derived antican
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Seyedan, Atefehalsadat, Mohammed Abdullah Alshawsh, Mustafa Ahmed Alshagga, Sanaz Koosha, and Zahurin Mohamed. "Medicinal Plants and Their Inhibitory Activities against Pancreatic Lipase: A Review." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–13. http://dx.doi.org/10.1155/2015/973143.

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Obesity is recognized as a major life style disorder especially in developing countries and it is prevailing at an alarming speed in new world countries due to fast food intake, industrialization, and reduction of physical activity. Furthermore, it is associated with a vast number of chronic diseases and disabilities. To date, relatively effective drugs, from either natural or synthetic sources, are generally associated with serious side effects, often leading to cessation of clinical trials or even withdrawal from the market. In order to find new compounds which are more effective or with les
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Mathai, Bincy Mariyam, Manu M. Joseph, Santhi Maniganda, et al. "Guanidinium rich dendron-appended hydnocarpin exhibits superior anti-neoplastic effects through caspase mediated apoptosis." RSC Advances 6, no. 58 (2016): 52772–80. http://dx.doi.org/10.1039/c6ra08724h.

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Medicinal plants have truly demonstrated their potential as a repository of active biomolecules with promising therapeutic potential and represent an important source for the identification of novel drug leads.
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