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1

Markman, Blanca Elena Ortega. "Caracterização farmacognóstica de Campomanesia xanthocarpa Myrtaceae ou Caracterização farmacognóstica de Campomanesia xanthocarpa Berg Myrtaceae." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/9/9138/tde-17032015-085231/.

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Campomanesia xanthocarpa Berg, espécie pertencente à família Myrtaceae, é conhecida popularmente como gabiroba. Diversas propriedades terapêuticas são atribuídas às espécies de Campomanesia, tais como, combate à disenteria, febre, cistites e uretrites. O presente trabalho objetiva contribuir para elaboração de monografia da espécie, através do estudo químico e farmacológico do extrato hidroalcoólico liofilizado e da droga vegetal constituída de folhas. Os caracteres farmacobotânicos da droga vegetal são apresentados com o intuito de auxiliar a diagnose. Dentre as principais características mac
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2

Madikane, Eliya Vukani. "The isolation of anti-mycobacterial compounds from South African medicinal plants." Doctoral thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/3289.

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3

Habtemariam, Solomon. "Phytochemical and pharmacological investigation of some medicinal plants." Thesis, University of Strathclyde, 1992. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21299.

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This thesis describes phytochemical and biological/pharmacological studies on six medicinal plants. Plant materials were extracted by ethanol, tested for their biological activity and then subjected to "bioassay-guided fractionation" to yield active and inactive compounds. The compounds were identified by standard physico-chemical techniques including UV, IR, NMR and ElMS. The crude ethanol extract of the leaves of Premna shcimperi was found to be antibacterial against gram positive bacteria (Staphylococcus aureus and Bacillus subtilis). An antibacterial bioassay-guided fractionation of the ex
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4

Sekhoacha, Mamello. "Antimalarial activity and cytotoxicity of some South African medicinal plants and their active constituents." Doctoral thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/3300.

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5

Kellermann, Tracy. "A Pharmacological investigations of South Africa Lichens, Dessication-tolerant Plants and Medicinal Tree, Warburgia Salutaris." Doctoral thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/3284.

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6

Garnett, Khanungnit Kym. "British Indo-Asians with diabetes mellitus : their adherence and use of medicinal plants." Thesis, University of Warwick, 2004. http://wrap.warwick.ac.uk/39296/.

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This thesis describes investigations of the usage of unconventional therapeutic methods to treat diabetes mellitus, with particular reference to Asian patients. Findings suggest that usage of unconventional therapeutic methods may persist in diabetic patients regardless of their language, religious belief, ethnic and cultural background or psychological states and adherence. The thesis is presented in two parts. Study 1, a preliminary study, was conducted in Thailand. Groups of adults with diabetes mellitus, aged 17 - 70+ years, were studied to assess the extent to which unconventional therape
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7

Essack, Magbubah. "Screening extracts of indigenous South African plants for the presence of anti-cancer compounds." Thesis, University of the Western Cape, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_8767_1210844967.

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<p>Early man dabbled with the use of plant extracts to cure ailments. This practice has been passed down from generation to generation and today more than 50% of the world'sdrugs are natural products or derivatives thereof. Scientists have thus established a branch of research called natural product research. This branch of research involves the identification and purification of secondary metabolites with a specific biological activity. The methodology involves the screening of plant products for a specific biological activity, purification of the biologically active natural product by separa
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8

Gumede, Bonginkosi. "A study of the immune response in murine experimental malaria, with special reference to the effects of South African medicinal plants, artesunate and chloroquine." Doctoral thesis, University of Cape Town, 2003. http://hdl.handle.net/11427/3283.

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9

Jooste, Clarese Staley. "Brine shrimp lethality test and acetylcholine esterase inhibition studies on selected South African medicinal plants." Thesis, University of the Western Cape, 2012. http://hdl.handle.net/11394/4047.

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>Magister Scientiae - MSc<br>Research into traditional medicines is often conducted in a multidisciplinary approach as motivated by a desire to understand them in as complete a manner as possible,realizing their chemistry, biology and pharmacology. One biological approach involves monitoring the cytotoxicity of the extracts of subfractions against the nauplii,Artemia salina (brine shrimp). Organic and aqueous extracts of seven South African medicinal plants was investigated for biological activity. Selected plant extracts was also evaluated for AChE inhibitory activity. The objectives of this
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10

Brine, Natalie Dawn. "Investigation of the phytochemistry and biological activity of isoquinoline alkaloids isolated from the South African medicinal plants, cyrtanthus sanguineus (Lindl.) walp. and cyrtanthus obliquus (L.f.)ait." Doctoral thesis, University of Cape Town, 2001. http://hdl.handle.net/11427/3274.

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Bibliography: p. 128-140.<br>The term "traditional medicine" refers to the ways of protecting and restoring health that existed before the arrival of modern medicine. These approaches to health belong to the traditions of each country and have been handed down from generatio to generation.
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11

Oliveira, Francisco de Assis. "Studies on the pharmacological properties of resin from Protium heptaphyllum (Aubl.) March. and its major constituent, alpha-and beta-amyrin mixture." Universidade Federal do CearÃ, 2005. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=69.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Protium heptaphyllum March (Burseraceae) populary known as âalmÃcegaâ is a popular medicinal plant largely encountered in the Amazon region, various States of Brazil and in several South American Countries. The oily amorphous exudate obtained from this plant is widely used in skin diseases, healing of ulcers, and as an analgesic and anti-inflamatory agent. Phytochemical studies reveled the presence of several monoterpenes and pentacyclic triterpenes such as a mixture of &#945;- e &#946; â amyrin, maniladilol and breine. The present
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12

Yang, Xiaotong, and 楊曉彤. "The anticancer mechanisms of polysaccharide peptide (PSP) derived fromthe Chinese medicinal fungus coriolus versicolor." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31246229.

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13

Hui, Tina Hsiao-Tin. "Design and test of a pharmacologic screen for the adaptogenic properties of plant drugs : a master's thesis." Scholarly Commons, 1992. https://scholarlycommons.pacific.edu/uop_etds/2231.

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Panax ginseng C.A. Mey. (Araliaceae), which has been known in China for more than 4000 years, occupies a particular place among tonic remedies. Pharmacological investigations of the roots have shown that the basic effect of ginseng's action is its capacity to increase the nonspecific resistance of the organism to various untoward influences. In addition to ginseng, another plant of the Araliaceae family is used in a similar manner and is known as Siberian ginseng, Eleutherococcus senticosus (Rupr. et Maxim.) Maxim.). Its roots have been very extensively investigated by Russian scientists. Gins
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14

Klank, Francisco Albuquerque. "Estudo etnofarmacológico e avaliação de atividades antinociceptiva de plantas medicinais da comunidade quilombola Mussuca, Laranjeiras/SE." Pós-Graduação em Desenvolvimento e Meio Ambiente, 2014. https://ri.ufs.br/handle/riufs/4276.

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The use of medicinal plants is present since the ancient times of civilization, currently being used as a complement in the treatment of pathologies. In Sergipe, more specifically in Mussuca community in Orange, the use of medicinal plants is closely linked to the cultural aspects of the community. Medicinal plants in Mussuca can be found in large quantities in the backyards of residents. Even as this massive amount of medicinal plants from various genres, few studies of pharmacological prospecting etnodirigida performed in maroon territories. In this sense, this work was to carry out an ethno
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15

李鵬. "Chemical and pharmacological studies on angiogenesis inhibitors from Salvia miltiorrhiza." Thesis, University of Macau, 2008. http://umaclib3.umac.mo/record=b2150645.

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16

Luchesi, Luana Aline. "Atividade antibacteriana, antifúngica e antioxidante de óleos essenciais." Universidade Tecnológica Federal do Paraná, 2017. http://repositorio.utfpr.edu.br/jspui/handle/1/2678.

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Pela crescente utilização das plantas medicinais e óleos essenciais na prevenção e tratamento de enfermidades, embasados nas propriedades antibacterianas, antifúngicas e antioxidantes é que objetiva-se com o presente trabalho identificar a composição e atividade antioxidante dos óleos essenciais de Lavandula angustifolia, Pogostemon cablin, Rosmarinus officinalis, Thymus vulgaris, Hedyosmun brasiliense, Psidium guajava, Baccharis dracunculifolia e Schinus terebinthifolius, bem como avaliar o potencial antibacteriano in vitro frente Staphylococcus aureus; Salmonella enteretidis;Escherichia coli
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17

朱侃. "嶺南道地藥材巴戟天和木蝴蝶的主要活性成分分離工藝研究 Research on the separation of main active components of Morindae officinalis Radix and Oroxyli Semen / by Zhu Kan". Thesis, University of Macau, 2014. http://umaclib3.umac.mo/record=b3132011.

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18

Santos, Cliomar Alves dos. "Mecanismos de ação antinociceptiva do extrato etanólico da entrecasca da Caesalpinia pyramidalis." Universidade Federal de Sergipe, 2015. https://ri.ufs.br/handle/riufs/3573.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>Pain is one of the major health problems, leading people to search for treatment. A pharmacological screening showed that the Caesalpinia pyramidalis ethanol extract (EE) reduces nociception behavior in the writhing, formalin, and hot plate tests in mice. In order to assess the mechanism of action of EE of C. pyramidalis, substrate, antagonists or inhibitors of different pathways involved in nociception were used in the writhing model. To select the dose, mice (n = 6 per group) were pretreated with EE of C. pyramidalis (10, 30, o
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19

Ostrosky, Elissa Arantes. "Avaliação da eficácia e segurança do extrato de folhas de Rubus rosaefolius Sm. visando a aplicação como conservante em produtos cosméticos." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-28092009-105736/.

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Os produtos cosméticos e farmacêuticos contendo componentes de origem natural têm aumentado significativamente nos últimos anos. Com o objetivo de utilizar esses componentes como conservante em formulações cosméticas, determinou-se a atividade antimicrobiana do extrato bruto de folhas de Rubus rosaefolius Sm. e suas frações. Aquele de melhor desempenho foi avaliado quanto à toxicidade in vitro e seu comportamento em formulações cosméticas (creme, gel e xampu), relacionado à estabilidade, eficácia do sistema conservante e compatibilidade epidérmica. A atividade antimicrobiana foi determinada pe
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Pasquale, Raquel Donatini De. "Atividades antiúlcera e antioxidante de Syzygium jambos (L.) Alston." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/9/9138/tde-04112016-160627/.

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O jambeiro (Syzygium jambos (L.) Alston) constitui uma das diversas espécies frutíferas e medicinais pertencentes à família Myrtaceae. O extrato hidroetanólico a 70% liofilizado de folhas de S. jambos apresentou atividade dose-dependente em modelo de úlcera gástrica induzida por etanol acidificado, sendo que a dose de 400 mg/kg reduziu significativamente a Área Total de Lesão (81,64%) e a Área Relativa de Lesão (65,11 %), em comparação ao grupo controle. Nesta dose, o extrato apresentou-se mais eficaz que o fármaco empregado como referência (lansoprazol 30 mg/kg). No modelo de indução de úlcer
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Taylor, Robin S. L. "Medicinal plants of Nepal: ethnomedicine, pharmacology, and phytochemistry." Thesis, 1996. http://hdl.handle.net/2429/6195.

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Information about the medicinal uses of forty-two plant species was collected from traditional healers and knowledgeable villagers from a variety of different ethnic groups in Nepal. Illnesses for which these plants are used are those perceived in western style medicine to be caused by bacterial, fungal or viral pathogens. Methanol extracts of the species were screened for activity against a variety of bacteria, fungi and viruses, under various light conditions to test for photosensitizers. Thirty-seven extracts showed activity against bacteria and thirty-five showed activity against fu
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22

Welch, Cara Renae. "Chemistry and pharmacology of Kinkéliba (Combretum micranthum), a west African medicinal plant." 2010. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000052288.

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23

Fawole, Olaniyi Amos. "Pharmacology and phytochemistry of South African traditional medicinal plants used as antimicrobials." Thesis, 2009. http://hdl.handle.net/10413/1224.

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Among all the major infectious human diseases, gastro-intestinal infections caused by microbial pathogens are a major cause of morbidity and infant death in developing countries, largely due to inadequate sewage disposal and contaminated water. Traditional health practitioners in South Africa play a crucial role in providing health care to the majority of the population. Many plants are locally used by South African traditional healers to treat microbial infections related to gastro-intestinal tracts. Ethnopharmacological and ethnobotanical studies using traditional knowledge as a selection st
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Aremu, Adeyemi Oladapo. "Pharmacology and phytochemistry of South African plants used as anthelmintics." Thesis, 2009. http://hdl.handle.net/10413/561.

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Traditional medicine in South Africa is part of the culture of the people and has been in existence for a long-time. Although animal components form part of the ingredients used, plant material constitutes the major component. South Africa is endowed with vast resources of medicinal and aromatic plants which have been employed for treatment against various diseases for decades. A large number of South Africans still depend on traditional medicine for their healthcare needs due to its affordability, accessibility and cultural importance. Helminth infections are among the variety of diseases tre
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"Studies on metabolism and pharmacological effect of active constituents of a Tibetan herbal medicine, halenia elliptica /cWong, Yan." Thesis, 2007. http://library.cuhk.edu.hk/record=b6074522.

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Halenia elliptica D. Don belongs to Gentianaceae family. It is often used as part of a traditional Tibetan medicine to treat hepatitis. In the present investigation, six major xanthone components were isolated and identified from Halenia elliptica. An HPLC/DAD/APCI/MS method was developed and validated for the quantitative analysis of these xanthones, including 1-hydroxy-2,3,5-trimethoxy-xanthone (HM-1), 1-hydroxy-2,3,4,7-tetramethoxy- xanthone (HM-2), 1-hydroxy-2,3,4,5-tetramethoxy-xanthone (HM-3), 1,7- dihydroxy-2,3,4,5-tetramethoxy-xanthone (HM-4), 1,5-dihydroxy-2,3-dimethoxy-xanthone (
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Chukwujekwu, Jude Chinedu. "A pharmacological study of some Nigerian medicinal plants." Thesis, 2005. http://hdl.handle.net/10413/10196.

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Petroleum ether, dichloromethane, and 80% ethanol extracts of 15 plant species collected in Nigeria were screened for in vitro antibacterial, anti-inflammatory and antimalarial activities. Antibacterial activity was tested using the agar diffusion method, while the minimum inhibitory concentrations (MIC) of the active extracts were determined using the microtitre serial dilution method. Most antibacterial activity detected was against Gram-positive bacteria with Staphylococcus aureus being the most susceptible. The highest activity was found in petroleum ether and dichloromethane leaf extracts
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Pillay, Prishania. "The toxicological properties of Scilla nervosa (Burch.) Jessop (Hyacinthaceae) in cultured HepG2 liver cells." Thesis, 2011. http://hdl.handle.net/10413/5370.

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Background and Aims of Study. Scilla nervosa is a member of the Hyacinthaceae plant family that has been naturalised in the grasslands of Southern Africa. The bulbs are traditionally used to treat a variety of ailments. For example, the Zulu people use aqueous decoctions of the bulbs as analgesics in the treatment of rheumatic fever, crushed bulbs are used by the Sotho people as laxatives and the Tswana people use cooked bulbs to treat infertility in women as well as cold aqueous extracts to treat infections. It was recently demonstrated in our laboratory that extracts prepared from the bulbs
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Bapela, Nchinya Benedict. "Isolation of Naphthoquinones from the roots of Euclea Natalensis and their invitro antimycobacterial activity and toxicity." 2006. http://upetd.up.ac.za/thesis/available/etd-09292006-130917.

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"Micropropagation and medicinal properties of Barleria greenii and Huernia hystrix." Thesis, 2009. http://hdl.handle.net/10413/653.

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The crisis of newly emerging diseases and the resistance of many pathogens to currently used drugs, coupled with the adverse side-effects of many of these drugs have necessitated the continuous search for new drugs that are potent and efficacious with minimal or no adverse side-effects. The plant kingdom is known to contain many novel biologically active compounds, many of which could potentially have a higher medicinal value when compared to some of the current medications. Indeed, the use of plants in traditional medicine, especially in African communities, is gaining more importance due to
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Serage, Sekgoro Andrew. "Isolation and characterization of antibacterial compounds in Combretum apiculatum Sond subsp. apiculatum exell." Diss., 2003. http://hdl.handle.net/2263/29176.

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"Identification, purification and biological studies of the lead compound from Chinese herbs for the reactivation of fetal hemoglobin expression." 2003. http://library.cuhk.edu.hk/record=b6073529.

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Xing Hongtao.<br>"February 2003."<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2003.<br>Includes bibliographical references (p. 149-176).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.
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"Study of the pharmacological activities of Panax notoginseng." 2003. http://library.cuhk.edu.hk/record=b6073563.

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by Lam Tin Lun.<br>"July, 2003."<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2003.<br>Includes bibliographical references (p. 308-327).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.
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Moyo, Mack. "Micropropagation and secondary metabolites of Sclerocarya birrea." Thesis, 2009. http://hdl.handle.net/10413/721.

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Tsepe, Wendy C. "Studies on molluscicidal properties of some South African medicinal plants used in the control of schistosomiasis in KwaZulu-Natal." Thesis, 2002. http://hdl.handle.net/10413/8605.

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Schistosomiasis is an important public health issue for rural communities located near,or around slow moving water bodies in the tropical and subtropical areas. Successful control of the disease involves multifaceted approaches, which include snail control, environmental sanitation, health education and chemotherapy. Although snail control might be an effective method of controlling schistosomiasis, there has been a general lack of control initiatives, largely due to the cost of available molluscicides. Plants offer a wide array of compounds which, on extraction, may show molluscicidal activit
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Ziqubu-Page, Thembelihle Thandekile. "An investigation of the antidiabetic herbal remedies used by traditional healers in Northern KwaZulu-Natal and their effect on blood glucose levels." Thesis, 1998. http://hdl.handle.net/10413/8546.

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This research study undertook to investigate and evaluate for efficacy and safety, the herbal remedies used for treating Diabetes mellitus in northern KwaZulu-Natal. In addition, it sought to gain knowledge and better understanding of traditional healing systems and the medicinal use of the natural flora. During the process of assimilating the desired information, the epidemiological and socio-economic factors which determine the form of medicine chosen by rural people in the region, were quantified. Both aspects of explanatory studies i.e. experimental and observational were used. Firstly, to
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Shaikh, Mahidansha Mahiboob. "Synthesis and biological activities of natural homoisoflavanones." Thesis, 2011. http://hdl.handle.net/10413/5905.

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Plants have formed the foundation of traditional medicine systems throughout the world for thousands of years and continue to provide mankind with new remedies for various ailments. A large portion of the black South African population still depends on medicinal plants as primary health care due to its affordability, accessibility and cultural importance. These medicinal plants need to be investigated since new lead compounds are often found in nature. Homoisoflavanones isolated from South African and Indian plants were found to exhibit anti inflammatory activities although the mechanism of ac
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Gallagher, Andrew Bruce. "A phytochemical investigation of two South African plants with the screening of extractives for biological activity." Thesis, 2006. http://hdl.handle.net/10413/8611.

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Two South African medicinal plants, Strophanthus speciosus and Eucomis montana, were investigated phytochemically. From Strophanthus speciosus a cardenolide, neritaloside, was isolated, whilst Eucomis montana yielded three homoisoflavanones, 3,9- dihydroeucomin, 4'-demethyl-3,9-dihydroeucomin, and 4'-demethyl-5-0-methyl-3,9- dihydroeucomin. The structures were elucidated on the basis of spectroscopic data. The homoisoflavanones were screened for anti-inflammatory activity using a chemiluminescent luminol assay, modified for microplate usage. All of the homoisoflavanones exhibited good inhibiti
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Gakuba, Emmanuel. "Isolation and characterisation of secondary metabolites of two asteraceae species, Artemisia afra and Elytropappus rhinocerotis." Thesis, 2009. http://hdl.handle.net/10413/639.

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In this study two medicinal plant species, namely Artemisia afra Jacq. ex. Willd and Elytropappus rhinocerotis Less. (L.f) (= Dicerotamnus rhinocerotis Koekemoer), both belonging to the family Asteraceae, have been investigated and different compounds isolated and characterised. Both species are important plants used in traditional medicine in general in Africa and particularly in South Africa. A. afra, commonly called "African wormwood" is one of 400 species belonging to the genus Artemisia and it is the only one indigenous to Africa. E. rhinocerotis is one of eight Elytropappus species which
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"Immunomodulatory effects and toxicity of mimosa pudica, the sensitive plant." Chinese University of Hong Kong, 1993. http://library.cuhk.edu.hk/record=b5887741.

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by Cheng Yuk Kwan, Anna.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1993.<br>Includes bibliographical references (leaves 104-112).<br>Acknowledgements<br>Table of Contents --- p.i<br>Abbreviations --- p.iv<br>Abstract --- p.vi<br>List of figures --- p.ix<br>List of tables --- p.xi<br>Chapter Chapter One: --- Introduction<br>Chapter 1.1 --- Objective and scope of the project --- p.1<br>Chapter 1.2 --- Literature review of Mimosa pudica<br>Chapter 1.2.1 --- Morphology of Mimosa pudica --- p.3<br>Chapter 1.2.2 --- Chemistry of Mimosa pudica --- p.5<br>Chapter 1.2.3 --- Uses in
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Sousa, Ana Isabel Ferreira da Silva. "Monografia da Achillea Millefolium." Master's thesis, 2017. http://hdl.handle.net/10437/8374.

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Orientação: Maria Lídia Palma<br>A Achillea millefolium L. é uma planta da família Asteraceae que está distribuída em várias partes do mundo, especialmente na Europa, Ásia e América. A prática medicinal do uso dos constituintes do milefólio é historiada desde a Mesopotâmia, e ao longo dos anos o intenso estudo que tem sido objeto é devido à sua composição e consequentemente à sua extensa atividade em diversas patologias/sintomatologia. Os constituintes fitoquímicos do milefólio são o óleo essencial, os alcaloides, os flavonoides, as lactonas sesquiterpénicas, os triterpenos e esteróis, os tan
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Jolayemi, Adebayo Taiwo Ezekiel. "Studies on some pharmacological properties of Capsicum frutescens-driven capsaicin in experimental animal models." Thesis, 2012. http://hdl.handle.net/10413/8111.

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The present study investigated pharmacological properties of Capsicum frutescens-derived capsaicin, including its analgesic, anti-inflammatory and coagulatory properties. The effects of capsaicin on gastrointestinal and myocardial muscles, as well as on myocardial ischaemic-reperfusion, were also investigated. Capsaicin pre-treatment in neonatal rats has been found to abolish the development of thermal hyperalgesia produced in a model of neuropathic pain in rats (Toth-Kasa et al., 1986). In addition, capsaicin sensitivity has been found to be dependent on continued presence of nerve growth fac
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"Bioactivity of chemically synthesized goniotriol and its analogues." Chinese University of Hong Kong, 1994. http://library.cuhk.edu.hk/record=b5888204.

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Hung Sau Ling.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1994.<br>Includes bibliographical references (leaves 131-137).<br>Table of Contents --- p.1<br>Acknowledgements --- p.V<br>Abbreviations --- p.VI<br>Aim of investigation --- p.IX<br>Abstract --- p.XI<br>Chapter Chapter 1 --- General Introduction --- p.1<br>Chapter 1.1 --- Cancer Chemotherapy --- p.2<br>Chapter 1.2 --- Plants as sources of useful drugs --- p.4<br>Chapter 1.3 --- Potent antitumor compounds found in Goniothalamus giganteus --- p.7<br>Chapter 1.4 --- Brief introduction of GONIOTRIOL --- p.8<br>Chapter 1
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Pereira, Isa Rito. "Artemisa annua L. e Cinchona L. : os seus princípios ativos nas estratégias de combate à malária." Master's thesis, 2014. http://hdl.handle.net/10437/5948.

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Orientação : Amílcar Roberto<br>A malária é a doença parasitária mais preocupante da atualidade, sendo um grave problema de saúde pública, principalmente em África onde mata maioritariamente crianças com idade inferior a 5 anos. As estratégias farmacoterapêuticas de combate à malária, baseiam-se principalmente nos fármacos derivados da artemisinina e em fármacos quinolínicos. A artemisinina e a quinina são fármacos provenientes das espécies vegetais, Artemisia annua L. e Cinchona L., respectivamente, e são conhecidos há muito tempo pela medicina tradicional. Estas substâncias são as qu
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Harbilas, Despina. "Antiobesity and antidiabetic activity of P. balsamifera, its active Salicortin, and L. laricina, medicinal plants from the traditional pharmacopoeia of the James Bay Cree." Thèse, 2012. http://hdl.handle.net/1866/8905.

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La prévalence de l’obésité, du diabète de type 2, et du syndrome métabolique, sont à la hausse chez les Cris d’Eeyou Istchee (CEI-Nord du Québec). Ces problèmes sont aggravés par leur diète non traditionnelle, leur sédentarité, ainsi que par une résistance culturelle aux produits pharmaceutiques. Afin de développer des traitements antidiabétiques culturellement adaptés, notre équipe a effectué une enquête ethnobotanique qui a identifié 17 plantes provenant de la pharmacopée traditionnelle des CEI. À partir des études de criblage effectuées in vitro, deux plantes parmi les 17 ont attiré notre a
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Marçal, Adriana Margarida Pereira de Oliveira Paulino. "Rumex crispus L.: monografia." Master's thesis, 2017. http://hdl.handle.net/10437/8609.

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Orientação: Maria Lídia Palma<br>Rumex crispus L., de nome comum Labaça-crespa, é uma planta endémica espalhada pelo mundo, sendo uma das mais infestantes em Portugal. Esta monografia, contem a descrição da planta, nomeadamente os sinónimos, variedades, o habitat e distribuição geográfica. São apresentados os extratos e a forma de obtenção. São referidos os constituintes mais importantes da planta nomeadamente, compostos fenólicos (antraquinonas, taninos, flavonoides), derivados naftalénicos, ácidos fenólicos (ácido gálico), mucilagens, o ácido oxálico, sais de ferro e fósforo. Fazem ainda pa
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Silva, Carla Sofia Estêvão dos Santos. "Plantas utilizadas como chás com propriedades anti-inflamatórias e antioxidantes." Master's thesis, 2012. http://hdl.handle.net/10437/3272.

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Orientação : Maria de Fátima Frazão<br>As plantas foram os primeiros recursos utilizados pelos povos como parte integral da fitoterapia. A fitoterapia, etimologicamente deriva dos termos gregos therapeia (tratamento) e phyton (vegetal). Significa o estudo de plantas consideradas medicinais e da sua aplicação no tratamento de doenças. Com o passar dos anos o uso das plantas como agentes terapêuticos, contribuiu muito para o desenvolvimento de novos fármacos pelo que, tornou-se imprescindível conhecer os seus princípios activos, os mecanismos de acção subjacentes, os efeitos secundários
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Eldeen, Ibrahim Mohamed Suliman. "Pharmacological investigation of some trees used in South African traditional medicine." Thesis, 2005. http://hdl.handle.net/10413/5526.

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South Africa is home to a wide diversity of cultural groups, all of which utilize the flora for a variety of purposes. This is true with regard to traditional medicine systems which are similar to those of the rest of Africa south of the Sahara, with diviners (sangomas) and herbalists (inyangas) as the key health providers. In addition, the Country is rich in plant diversity with some 30 000 species of flowering plants - almost one tenth of the worlds recorded higher plants. This incorporates a large diversity of plants including trees, shrubs, herbs, bulbs and corms. The adverse effects of tr
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Shang, Nan. "Bioassay-guided fractionation of Larix laricina du Roi, and antidiabetic potentials of ethanol and hot water extracts of seventeen medicinal plants from the traditional pharmacopeia of the James Bay Cree." Thèse, 2013. http://hdl.handle.net/1866/12626.

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Nous avons utilisé une approche ethnobotanique pour identifier des espèces de plantes utilisées par les Cris afin de traiter les symptômes du diabète de type 2. Larix laricina du Roi (L. laricina) a récemment été identifiée comme une des meilleures plantes qui a stimulé le transport de glucose dans les cellules C2C12 et fortement potentialisé la différenciation des 3T3-L1 en indiquant une sensibilité potentiellement accrue à l’insuline. Ensuite, ces études de criblage ont été effectuées sur des extraits éthanolique (EE) en utilisant une série de bioessais in vitro. Cependant, les préparations
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Ladeiras, Diogo Filipe Bernardo. "Estudo de compostos bioactivos e actividades biológicas do alecrim (Rosmarinus officinalis L.)." Master's thesis, 2015. http://hdl.handle.net/10437/6179.

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Orientação: Patrícia Rijo<br>As plantas constituem um recurso terapêutico ainda hoje muito utilizado. O interesse mundial no uso das plantas medicinais tem sido crescente, com os seus efeitos benéficos a serem redescobertos para o desenvolvimento de novos medicamentos. Pela primeira vez, com esta dissertação, foi elaborada uma revisão bibliográfica sistemática com o objectivo de clarificar o estado actual dos estudos sobre Rosmarinus officinalis L., elucidando quais os seus compostos e as actividades biológicas mais relevantes. Para tal, foi feita uma pesquisa na base de dados ‘PUBMED’,
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Antão, Ana Margarida Ribeirinha. "Estudo de compostos bioactivos e actividades biológicas de Plectranthus ecklonii Benth." Master's thesis, 2015. http://hdl.handle.net/10437/6177.

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Orientação: Patrícia Rijo<br>O uso de produtos à base de plantas para o tratamento, cura e prevenção de doenças, constitui uma das mais antigas práticas medicinais da humanidade. De facto, uma fracção significativa das populações dos países em desenvolvimento permanece dependente dos conhecimentos ancestrais sobre plantas para os seus cuidados de saúde. Ainda assim, continua a existir uma lacuna entre os progressos observados na farmácia clínica e os no campo da fitoterapia e da medicina tradicional, continuando muitos produtos naturais com actividade biológica por identificar. As espécies de
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