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Dissertations / Theses on the topic 'Medicinal plants – Research – South Africa'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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1

Chadwick, Wayne. "Metabolic effects brought about by tricyclic antidepressants and the contribution of a medicinal plant in alleviating high fat diet induced insulin resistance in male wistar rats." Thesis, Nelson Mandela Metropolitan University, 2006. http://hdl.handle.net/10948/461.

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Type II diabetes is becoming a growing problem in developed countries worldwide. The median age for diagnosis was around sixty, but recent surveys have shown that the entire age distribution curve shifting left. The incidence of type II diabetes is thought to be parallel with the growing rate of obesity associated with an unhealthy western diet. Type II diabetes is an expensive disease to manage, it is for this reason that cheaper medication needs to be investigated in the form of traditional plants, such as Sutherlandia frutescens. Prescription medication, such as tricyclic antidepressants, m

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2

Van, Huyssteen Mea. "Collaborative research with traditional African health practitioners of the Nelson Mandela Metropole : antimicrobial, anticancer and anti-diabetic activities of five medicinal plants." Thesis, Nelson Mandela Metropolitan University, 2007. http://hdl.handle.net/10948/663.

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The promotion and development of indigenous knowledge pertaining to the traditional African healing system is one of the prime objectives set out by the South African government. Despite excellent research opportunities and funding, the biggest problem with ethnopharmacological research is a lack of interaction with indigenous communities, which tends to dilute the benefits this research has to offer these communities. The primary aim of this study was thus to promote the traditional African healing system through collaborative medicinal plant research with local traditional health practitione

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3

Lekganyane, Maleho Annastasia. "Isolation and characterization of antibacterial compounds from five selected plants used against bacteria which infects wounds." Thesis, University of Limpopo, 2015. http://hdl.handle.net/10386/1259.

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Thesis (M.Sc. (Microbiology)) --University of Limpopo, 2015<br>Five plant species: Ziziphus mucronata, Senna italica, Lantana camara, Ricinus communis and Lippia javanica, were selected for this study based on their use in traditional medicine. In preliminary screening, crude extracts were prepared using hexane, dichloromethane (dcm), acetone and methanol. Phytochemical profiles on Thin Layer Chromatography plates of the extracts were obtained by developing the plates in mobile phases of varying polarity. Tests for compounds such as tannins, flavonoids, alkaloids, phlobatannins, terpenes, ster

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4

Adams, Zanele. "Comparative phytochemical analyses of Aloe Ferox Mill. found in Eastern and Western Cape provinces in South Africa." Thesis, University of Fort Hare, 2013. http://hdl.handle.net/10353/d1013114.

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5

Faulconbridge, Steven Craig. "Propagating some commonly-used South African medicinal plants with compost and vermitea." Thesis, Nelson Mandela Metropolitan University, 2013. http://hdl.handle.net/10948/d1020316.

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The use of many of South Africa’s medicinal plants has shown marked increase with over 27 million users in South Africa alone. Most plants are still being unsustainably wild-harvested, a major concern for biodiversity conservation. Commercial interest in certain more commonly-used species has increased, with potential to cultivate medicinal plants on a more sustainable basis. Focus has shifted from conventional use of synthetic fertilisers, pesticides and fungicides to more organic methods of plant propagation. Aqueous extract derived from earthworm composted food waste (vermitea) was used to

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6

Mathabe, Matlakala Christina. "Bioactivity of medicinal plants used for treatment of diarrhoea in selected villages in Limpopo Province, South Africa." Thesis, University of Limpopo (Turfloop Campus), 2006. http://hdl.handle.net/10386/925.

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7

Pruissen, Megan Colleen. "Evaluation of plant extracts : artemisia afra and annona muricata for inhibitory activities against mycobacterium tuberculosis and human immunodeficiency virus." Thesis, Nelson Mandela Metropolitan University, 2013. http://hdl.handle.net/10948/d1019845.

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Mycobacterium tuberculosis and Human Immuno-Deficiency Virus (HIV) have a high prevalence in South Africa. The development and spread of drug resistant tuberculosis is a serious problem which is exacerbated by tuberculosis (TB) co-infection in HIV patients. Traditional medicinal plants like Annona muricata and Artemisia afra are used for respiratory ailments and antiviral therapies respectively. The aim of this study was to evaluate Annona muricata (ethanolic extract) and Artemisia afra (ethanolic and aqueous extracts) for inhibitory activities against M. tuberculosis and HIV. In vitro bioassa

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8

Malamule, R. J. "Mathyelo ya mavito ya misinya yo tshungula mavabyi eka Skhukhuza, eMpumalanga : maendlelo ya onomasitiki." Thesis, University of Limpopo, 2015. http://hdl.handle.net/10386/1771.

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9

Chinyama, Robert Fred. "Biological activities of medicinal plants traditionally used to treat Septicaemia in the Eastern Cape, South Africa." Thesis, Nelson Mandela Metropolitan University, 2009. http://hdl.handle.net/10948/1274.

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Over the past 25 years, there has been a resurgence of worldwide scientific research in the fields of ethnopharmacology. The Western world has acknowledged the continued use of traditional medicines by the majority of third world countries, and the need for novel drug development. Hence, much of the pharmaceutical research in recent years has focused on the ethnobotanical approach to drug discovery (Light et al., 2005). In South Africa, as in most developing parts of the world, traditional herbal medicine still forms the backbone of rural healthcare. The government health services in South Afr

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10

Essack, Magbubah. "Screening extracts of indigenous South African plants for the presence of anti-cancer compounds." Thesis, University of the Western Cape, 2006. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_8767_1210844967.

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<p>Early man dabbled with the use of plant extracts to cure ailments. This practice has been passed down from generation to generation and today more than 50% of the world'sdrugs are natural products or derivatives thereof. Scientists have thus established a branch of research called natural product research. This branch of research involves the identification and purification of secondary metabolites with a specific biological activity. The methodology involves the screening of plant products for a specific biological activity, purification of the biologically active natural product by separa

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11

Matanzima, Yonela. "Quantitative and qualitative optimization of antimicrobial bioactive constituents of Helichrysum cymosum using hydroponics technology." Thesis, Cape Peninsula University of Technology, 2014. http://hdl.handle.net/20.500.11838/849.

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Thesis submitted in fulfilment of the requirements for the degree Master of Technology: Horticulture in the Faculty of Applied Sciences at the Cape Peninsula University of Technology<br>The high demand for medicinal plants has favoured over-exploitation of wild plants. The search for alternative and sustainable methods of medicinal plant cultivation is imperative and desirable. Biotechnological approaches particularly hydroponic technology has the potential for large scale plant cultivation and production of secondary metabolites. The current study aims at optimizing the production of a

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12

Polori, Ketlareng Liza. "The medicinal properties of ipomoea oblongata E.Mey. ex Choisy." Thesis, Bloemfontein: Central University of Technology, Free State, 2014. http://hdl.handle.net/11462/671.

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Thesis (M. Tech. (Biomedical Technology)) -- Central University of Technology, Free State, 2014.<br>Traditional medicine has been known by mankind since ancient times as a healthcare system. All cultures have used herbs throughout history and it was an integral part of the development of modern civilization. Primitive man observed and appreciated the great diversity of plants available to him. Plants provided food, clothes, shelter and medicine and still play a vital role in rural villages of South Africa. The medicinal uses of plants and animals have been developed through trial and error. He

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13

Kellermann, Tracy. "A Pharmacological investigations of South Africa Lichens, Dessication-tolerant Plants and Medicinal Tree, Warburgia Salutaris." Doctoral thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/3284.

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14

Fewell, William. "An assessment of the in vitro neuroprotective potential of selected Algerian and South African medicinal plant extracts." Thesis, Nelson Mandela Metropolitan University, 2015. http://hdl.handle.net/10948/8608.

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It is estimated by the World Health Organization (WHO) that by 2040 neurodegenerative disorders will collectively surpass cancer as the primary cause of death in industrialised countries (WHO,2006). Natural flora represents one of the most important therapeutic sources in modern drug discovery, however only a limited number of plant species have been screened for their neuroprotective value. The neuroprotective potential of eleven Algerian and two South African medicinal plant extracts were assessed in this study, aiming to identify promising candidates for future research. Neurodegenerative d

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15

Venables, Luanne. "In vitro induction of cell death pathways by artemisia afra extract and isolation of an active compound, isoalantolactone." Thesis, Nelson Mandela Metropolitan University, 2014. http://hdl.handle.net/10948/d1021087.

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Artemisia afra is one of the oldest, most well known and widely used traditional medicinal plants in South Africa. It is used to treat many different medical conditions, particularly respiratory and inflammatory ailments. There is no reported evidence of its use for the treatment of cancer but due to its reported cytotoxicity, an investigation of the mode of cell death induced by an ethanol A. afra extract using two cancer cell lines was done. IC50 values of 18.21 and 31.88 μg/mL of ethanol extracts were determined against U937 and HeLa cancer cells, respectively. An IC50 value of the aqueous

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16

Wilson, Katherine Leigh. "An investigation into the antibacterial activites of medicinal plants traditionally used in the Eastern Cape to treat lung infections in cystic fibrosis patients." Thesis, Nelson Mandela Metropolitan University, 2004. http://hdl.handle.net/10948/242.

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Lung infections in cystic fibrosis (CF) patients are very serious and are usually fatal. Prolonged antibiotic treatment can result in the development of antibiotic resistance. Thus, studies are required to determine if traditional medicinal plants have any significant effects (i.e. antibacterial effects in this case) on certain bacteria causing lung infections in CF patients, providing possible alternative treatment. The aim of this study was to test the effects of several Eastern Cape medicinal plants on specific bacteria causing lung infections in CF patients, for possible antibacterial acti

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17

Monakisi, Charlotte M. "Knowledge and use of traditional medicinal plants by the Setswana-speaking community of Kimberley, Northern Cape of South Africa." Thesis, Stellenbosch : Stellenbosch University, 2007. http://hdl.handle.net/10019.1/18589.

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Thesis (MSc)--University of Stellenbosch, 2007.<br>ENGLISH ABSTRACT: The majority of South Africans still depend on the use of traditional remedies, as these are sometimes the only types of health care systems available, especially within rural communities. South Africa comprises approximately 400 000 traditional healers and an estimated 60 to 80% of individuals consulting such traditional healers. As a result, the over-harvesting of many traditional medicinal plants has become a threat to the country’s species diversity and has resulted in the scarcity of certain medicinal plant species.

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18

Kimbugwe, Francis Kambugu. "An investigation of factors which influence integrating indigenous knowledge of medicinal plants into the learning programme for Grade 9 General Science." Thesis, Rhodes University, 2001. http://hdl.handle.net/10962/d1003506.

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This study explores knowledge of some medicinal plants amongst the sub-urban community of and around a township in the Eastern Cape province. This qualitative interpretivist case study presents the prior knowledge of medicinal plants possessed by Grade 9 learners, which is used as a springboard toward interviewing traditional healers, herbal practitioners and lecturers at a university in the departments of Botany and Pharmacy. The data obtained from the informants reveals the factors that can influence integration of indigenous knowledge of medicinal plants in the learning programme for grade

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19

Shai, LJ, JN Eloff, N. Boaduo, et al. "Yeast alpha glucosidase inhibitory and antioxidant activities of six medicinal plants collected in Phalaborwa, South Africa." Elsevier, 2010. http://encore.tut.ac.za/iii/cpro/DigitalItemViewPage.external?sp=1001248.

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Abstract Recent decades have experienced a sharp increase in the incidence and prevalence of diabetes mellitus. One antidiabetic therapeutic approach is to reduce gastrointestinal glucose production and absorption through the inhibition of carbohydrate-digesting enzymes such as α- amylase and α-glucosidase and α-amylase. The aim of the current study was to screen six medicinal plant species, with alleged antidiabetic properties for α-glucosidase inhibitory activities. Powdered plant materials were extracted with acetone, and tested for ability to inhibit baker's yeast α-glucosidase and α-amyla

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20

Yengkopiong, P. J. "The assessment of the therapeutic and toxicological properties of carpobrotus acinaciformis and schkuhria pinnata used in traditional medicine in South Africa." Thesis, University of Limpopo (Medunsa Campus), 2005. http://hdl.handle.net/10386/846.

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21

Tembeni, Babalwa. "Seasonal variations of essential oil composition and some biological evaluation of Pelargonium inquinans (L.) Ait. South Africa." Thesis, University of Fort Hare, 2016. http://hdl.handle.net/10353/6281.

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Pelargonium inquinans which belongs to the family Geraniaceae, is an essential oil yielding plant. P. inquinans was collected from two different sites in Grahamstown (wild) and Alice, at the University of Fort Hare botanical garden. Authentication of the plant was done by Dr. T. Dold at Schonland herbarium, and the voucher specimen being T01. This study is focused at determining the chemical constituents and biological properties of the essential oils of wild and cultivated P. inquinans across different seasons, as the plant grows throughout the year. Seasonal collection of wild and cultivated

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22

Mintsa, Mi Nzue Agnan Pierre. "Use and conservation status of medicinal plants in the Cape Peninsula, Western Cape Province of South Africa." Thesis, Stellenbosch : University of Stellenbosch, 2009. http://hdl.handle.net/10019.1/1590.

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23

Louw, Melissa. "The social practices of cultivation and gathering of medicinal plants in Ebenhaezer, Matzikama, Western Cape, South Africa." Thesis, University of the Western Cape, 2016. http://hdl.handle.net/11394/5533.

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Magister Artium - MA<br>This study aims to investigate the extent to which the increasing demand for medicinal plant and the resulting pressure on local cultivators to meet the demand impact upon cultivation and gathering practices of such plants. The specific focus is on the social practices of cultivation and gathering of medicinal plants in Ebenhaezer, a small-scale peri-urban town in Matzikama in the Western Cape Province in South Africa. This study will utilize survey and in-depth interviews techniques complemented with a focus group discussion on observed cultivation and gathering practi

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24

Van, Gend Tania Anli. "Effect of a South African medicinal plant on antiretroviral drug induced abnormalities in rats." Thesis, Nelson Mandela Metropolitan University, 2008. http://hdl.handle.net/10948/1080.

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The worldwide AIDS epidemic is known to have had a profoundly negative social, economic and personal impact and has taken a heavy toll on existing health care systems, particularly in developing countries. South Africa is experiencing an HIV epidemic with enormous social and economic consequences. Lopinavir/ritonavir antiretroviral treatment has been accredited with having a significantly positive effect and is a key advance in controlling HIV morbidity and mortality. An indigenous South African medicinal plant, Sutherlandia frutescens, known for its anti-diabetic properties and immune-boostin

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25

Davison, Candice. "A biochemical study of the antidiabetic and anticogulant effects of Tulbaghia Violacea." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/1523.

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Secondary metabolites derived from plants, especially those used by traditional healers, are at the forefront of new drug development in combating diseases such as cancer and diabetes. Garlic is employed in indigenous medicine all over the world for the treatment of a variety of diseases. Dietary garlic has been recognized for its beneficial health effects. In particular, garlic consumption has been correlated with (i) reduction of risk factors for cardiovascular diseases and cancer, (ii) stimulation of immune function, (iii) enhanced detoxification of foreign compounds, (iv) hepatoprotection,

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26

Mgobozi, Vuyokazi. "Heavy metal content absorption and medicinal potential of Egeria densa (Planch.) Casp." Thesis, University of Fort Hare, 2013. http://hdl.handle.net/10353/d1013121.

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The contamination of heavy metals in the environment is a looming concern worldwide. Egeria densa (Planch) (Submerged aquatic plant) from two ponds: Site A with co-ordinates (32º 48’22.04”S; 26°48’58.79” E) and Site B with co-ordinates (32°48’33.25”S; 26°48’33.25”S) in Alice (Eastern Cape) was evaluated for its ability to absorb heavy metals, phytochemical constituents, antimicrobial activity and ultra-structure using standard analytic procedures. Cadmium (Cd), copper (Cu), iron (Fe), lead (Pb), manganese (Mn), and zinc (Zn) were measured in water, sediments and plant. The concentrations of th

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27

Appidi, Jaipal Reddy. "Evaluation of antidiarrhoeal and toxicological properties of Hermannia Incana cav.: a South African medicinal plant." Thesis, University of Fort Hare, 2010. http://hdl.handle.net/10353/259.

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Hermannia incana Cav. (Sterculiaceae), known as sweet yellow bells, is a medicinal plant used by the people of the Eastern Cape for the treatment of stomach-ache and diarrhoea. It has purgative and diaphoretic effects. It is a prostrate herb with yellow flowers and sparsely hairy and slightly glandular leaves, occurring in grassland and marshes in the Eastern Cape Province of South Africa. Based on the ethnomedical uses of this plant, the research project was designed to evaluate its antidiarrhoeal and toxicological properties. An ethnobotanical study of plants used for the treatment of diarrh

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28

Emamzadeh-Yazdi, Simin. "Antiviral, antibacterial and cytotoxic activities of South African plants containing cardiac glycosides." Diss., University of Pretoria, 2013. http://hdl.handle.net/2263/33163.

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South Africa has one of the richest and diverse floras in the world with over 30000 species of higher plants. There are approximately 3000 species of medicinal plants in South Africa. The discovery of active compounds in medicinal plants plays a strategic role in the phytochemical investigation of crude plant extracts. Secondary metabolites of medicinal plants are a major source of drugs for the treatment of various health disorders. Cardiac glycosides are one of the subgroups of steroids modified from terpenoids. The existence of cardiac glycosides in some plant species often indicates toxici

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29

Gololo, Sechene Stanley. "Biological activity analysis of the crude extract of the Senna species : structure elucidation of a compound with antioxidant activity." Thesis, University of Limpopo, 2008. http://hdl.handle.net/10386/526.

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Thesis (M.Sc.) --University of Limpopo, 2008<br>Senna species, a member of the Fabaceae family (subfamily Caesalpinaceae), is widely used traditionally to treat a number of disease conditions such as sexually transmitted diseases and some forms of intestinal complications. In this study the roots of Senna species, collected from Zebediela region of the Limpopo province (R.S.A), were ground to a fine powder and extracted with acetone by cold/shaking extraction method. The phytochemical composition of the extract was then determined by thin layer chromatography (TLC). The chromatograms were visu

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Qodi, Noluntu. "In Vitro tests for immunomodulatory effects of medicinal plants used in the treatment of Malaria in South Africa." Master's thesis, University of Cape Town, 2001. http://hdl.handle.net/11427/3454.

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Bibliography: leaves 78-80.<br>Using the ethno-medicinal data approach, nine South African plants used traditionally in the treatment of malaria were collected and evaluated for cytotoxic and lymphocyte-proliferating effects. These included Acokanthera oppositofolia, Zanthoxylum capense, Glycyrrhiza glabra, Harpephyllum caffrum, Lippia javanica, Pentanisia prunneloides, Psidium guajava, Typha capensis and Cannabis sativa. The cytotoxic effect of the aqueous, methanol and dichloromethane extracts of these plants was evaluated in vitro in Rat-1 fibroblasts there was no observable difference in c

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31

Freidberg, Ryno. "An investigation into the antimicrobial and anticancer activities of Geranium incanum, Artemisia afra and Artemisia absinthium." Thesis, Nelson Mandela Metropolitan University, 2009. http://hdl.handle.net/10948/1045.

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It has been estimated that between 3000 and 4000 plant species are used for their medicinal properties throughout South Africa, with approximately 27 million South Africans making use of traditional medicines. Of this 27 million, 3 million South Africans rely on traditional medicine as their primary source of health care. Of the 250 000 to 500 000 known plant species, very few have been investigated for their pharmacological qualities, and compounds of significant medicinal value may still remain undiscovered in many plant species. The aims of this study included investigating the antimicrobia

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32

Mtshali, Cynthia Sibongiseni. "An investigation of environmental knowledge among two rural black communities in Natal." Thesis, Rhodes University, 1995. http://hdl.handle.net/10962/d1003505.

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This study elicits and documents knowledge of the natural environment amongst two rural Black communities in Natal namely, the districts of Maphumulo and Ingwavuma.Twenty members of these communities who are older than 60 years of age were interviewed, as older people are considered by the researcher to be important repositories of environmental knowledge. This study records a variety of animals hunted in these communities and discusses various activities associated with this activity. It examines the gathering and the use of wild edible plants like fruits and spinach, and of wild plants alleg

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Bosch, Janine. "Production of biologically active recombinant HIV-1 protease and intehrase for the purpose of screening medicianl plant extracts." Thesis, Nelson Mandela Metropolitan University, 2009. http://hdl.handle.net/10948/1056.

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Human immunodeficiency virus (HIV) and its gradual weakening of the immune system is an ever growing threat. Acquired immune deficiency syndrome (AIDS), the final stage of HIV, renders a person vulnerable to various opportunistic infections, which in the end lead to death. Apart from intensive vaccine studies, treatment research mainly focuses on preventing the individual HIV enzymes (reverse transcriptase, integrase and protease) from performing their functions. Entry inhibitors, however, block viral entry into the cell, while antisense drugs lock onto the viral genome to keep it from functio

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Harnett, Siobhán Margaret. "In vitro anti-HIV activities of Sutherlandia frutescens and Lobostemon trigonum extracts." Thesis, University of Port Elizabeth, 2004. http://hdl.handle.net/10948/347.

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Currently, the approved anti-HIV drugs on the market only target the three HIV enzymes: reverse transcriptase, protease and more recently, integrase. Due to the limited nature of the current therapy, it is possible that a multi-drug resistant virus can emerge. The main concerns in developing countries however, are the expense and availability of the drugs and because of this, it is essential to investigate all alternatives. Traditional medicine offers many advantages as compared to allopathic treatment in so far as being relatively cheaper, accessible and it is broadly accepted in the populati

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Chigor, Chinyere Blessing. "Development of conservation methods for gunnera perpensa l.: an overexploited medicinal plant in the Eastern Cape, South Africa." Thesis, University of Fort Hare, 2014. http://hdl.handle.net/10353/d1019832.

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South Africa, many plants which are used in traditional medicines are collected from wild populations. The high demand for trade and use of these medicinal plants place an enormous pressure on their natural populations, especially because they are indiscriminately harvested. The most affected of these plant species are those harvested from their underground parts, among which is Gunnera perpensa L. Gunnera perpensa is of considerable ethnobotanical interest in traditional medicine because of its wide usage. The rhizomes are widely used and indiscriminately collected in large quantities from th

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Kibiti, Cromwell Mwiti. "Evaluation of the medicinal potentials of Bulbine Abyssinica A. rich in the management of diabetes mellitus in the Eastern Cape, South Africa." Thesis, University of Fort Hare, 2016. http://hdl.handle.net/10353/3077.

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Diabetes mellitus is a chronic physiological carbohydrate metabolic disorder with significant impact on the economy, quality of life and life expectancy in South Africa. Herbal medicine has become the alternative therapy in the management of this disease. However, their safety and effectiveness have not been investigated. To address this, one of the plants used in Eastern Cape Province, South Africa, Bulbine abyssinica A. Rich (Asphodelaceae), was evaluated. Bulbine abyssinica is one of the species used in the management of diabetes mellitus. This plant was mentioned during an ethnobotanical s

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Ah, Goo Delia Felecia Stephanie. "The contribution of the trade in medicinal plants to urban livelihoods: a case study of the informal markets in Nelson Mandela Bay Municipality, Eastern Cape." Thesis, Nelson Mandela Metropolitan University, 2012. http://hdl.handle.net/10948/d1011601.

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The commercialisation of natural resources such as medicinal plants is a strategy that is increasingly being employed by poor people in developing countries such as South Africa, as a means of generating an income. Increasing economic hardship and a lack of employment opportunities in the formal sector of the economy has led to many urban dwellers seeking alternative means of meeting their everyday livelihood needs. Although the contribution of natural resources to subsistence economies is widely recognised, there are few studies that have examined the significance of the trade in medicinal pl

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Njume, Collise. "Phytochemical analysis and bioactivity of selected South African medicinal plants on clinical isolates of Helicobacter pylori." Thesis, University of Fort Hare, 2011. http://hdl.handle.net/10353/449.

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Medicinal plants have been used as traditional medicine in the treatment of numerous human diseases for thousands of years in many parts of the world. In the developing world, especially in rural areas, herbal remedies continue to be a primary source of medicine. Scientifically, medicinal plants have proven to be an abundant source of biologically active compounds, many of which have already been formulated into useful therapeutic substances or have provided a basis for the development of new lead molecules for pharmaceuticals. Antibiotic resistance, undesireable side effects and expences asso

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Dubeni, Zimasa Busisiwe. "Phytochemical screening and thin layer chromatographic profiling of aloe vera (l) burn. f growing in South Africa." Thesis, University of Fort Hare, 2013. http://hdl.handle.net/10353/d1016169.

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The chemical profiling, characterization of Aloe products and phytochemical properties of Aloe vera were studied. The adulteration of commercial products derived from medicinal plants has been a major muddle for both the society and the pharmaceuticalindustry. Economically motivated adulteration includes the potential for contaminated, sub‐potent or counterfeit medication to enter the supply chain at several levels, from the production of raw ingredients through to the point of retail sale. Darwin’s theory of evolution states that, species undergo genetic variation with time to adapt to enviro

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Stafford, Gary Ivan. "Storage of frequently used traditional South African medicinal plants." Thesis, 2003. http://hdl.handle.net/10413/5639.

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The post-harvest physiology of nine frequently used indigenous southern African medicinal plants was investigated, in particular the effects of storage time and accelerated ageing on the biological activity and chemical constituents of these plants. Water, ethanol and hexane extracts of fresh plant material as well as material that had been stored in dry form in paper bags at room temperature for 90 days (short-term) were tested. Three bioassays, the COX-1 anti-inflammatory assay, nematode anthelmintic assay and minimum inhibitory concentration anti-bacterial assay, were used to determine biol

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Duncan, Andrew Cameron. "An investigation of plants used in South Africa for the treatment of hypertension." Thesis, 1998. http://hdl.handle.net/10413/8559.

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In most countries, as many as 15 to 25% of the adult population have raised blood pressure. People with hypertension, and even those with mild elevation of blood pressure, are at an increased risk of cardiovascular disease, whether or not the symptoms are present. The risk of serious cardiovascular disease varies greatly among individuals and is also determined by a variety of concomitant risk factors other than the level of blood pressure. Hypertension develops as a result of disturbances of the body's blood pressure regulating system. The biological activity of the renin-angiotensin systems

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Ramalivhana, Naledzani Jeoffry. "Molecular characterization of Aeromonas hydrophila and antimicrobial activities of selected medicinal plants against pathogenic isolates from water and stool samples in the era of HIV/AIDS in Limpopo Province, South Africa." Thesis, 2010. http://hdl.handle.net/10500/4309.

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Aeromonas hydrophila is distributed widely in nature and is responsible for an array of human infections. Several studies on the isolation and characterisation of the organism abound. Although there are reports on the antibiotic resistance profiles of the organism, these reports have not been updated in Limpopo province, South Africa despite the established fact that antibiograms vary with time and geographical area. Antibiotic resistance and pathogenesis of an organism are dependent on a host of factors such as the production of extended spectrum beta-lactamases and the genetic profiles

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Mankga, Ledile Thabitha. "DNA barcoding Medicinal plants of South Africa." Thesis, 2013. http://hdl.handle.net/10210/8532.

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M.Sc. (Botany)<br>The market and public demand for medicinal plants over the past few decades has increased dramatically with more than 1 000 plant species actively traded for medicinal purposes throughout South Africa. Intensive harvesting of wild material is now acknowledged as a serious threat to biodiversity in this country. Also the substitution of a valuable commodity (medicinal plant) by a cheaper alternative (other plant species), either inadvertently due to misidentification, or deliberately to cheat consumers, raises some serious concerns as these adulterants may not be as effective

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Ondua, Moise. "Antioxidative, analgesic and anti-inflammatory activities of Acokanthera oppositifolia, Plantago lanceolata, Conyza canadensis, and Artemisia vulgaris." Diss., 2015. http://hdl.handle.net/10500/19169.

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The anti-inflammatory properties of four medicinal plants were investigated. These plant extracts were subjected to screening for their possible effects as antioxidative, analgesic, and anti-inflammatory agents. In the antioxidant activity, the Plantago lancelota extracts resulted in an IC50 value of 0.4 mg/mL compared to the positive control quecertin with IC50 0.04 mg/mL Plantago lanceolata inhibited COX-2 activity with IC50 values of 0.41 mg/mL. However, the COX-1 inhibition indicated an IC50 of 68.99 mg/mL. The lipoxygenase assay indicated that Plantago lanceolata was the most active plant

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Okem, Ambrose. "Pharmacological activities of selected South African medicinal plants." Thesis, 2011. http://hdl.handle.net/10413/8588.

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The use of traditional medicine is a popular practice in South Africa especially among rural dwellers due to several reasons such as availability of natural products, cultural beliefs, preference of natural products to synthetically derived drugs and the high cost of modern drugs. Traditional healers in South Africa play key roles in administering treatment for all sorts of ailments using plants. The aim of this study was to evaluate the efficacy of seven selected medicinal plants that are used in traditional medicine to treat stomach-related ailments for their pharmacological and phytochemica

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Street, Renée Anne. "Heavy metals in South African medicinal plants." Thesis, 2008. http://hdl.handle.net/10413/801.

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Plants are able to take up and accumulate certain environmental contaminants such as heavy metals. When the plants are ingested by man, these contaminants are transferred along the food chain. Due to the poorly regulated medicinal plant trade in South Africa, many opportunities exist for heavy metal contamination of medicinal plants namely contaminated harvest sites as well as poor drying, processing, storage, transport and manufacturing conditions. The concentrations of five heavy metals (As, Cd, Co, Ni, Pb) and six microelements (B, Cu, Fe, Mn, Mo, Zn) were determined in some commonly used S

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Hurinanthan, Vashka. "Anti-HIV activity of selected South African medicinal plants." Thesis, 2013. http://hdl.handle.net/10321/916.

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Submitted in complete fulfilment for the Degree of Doctorate of Technology (Biotechnology)--Durban University of Technology, 2013.<br>South Africa has the largest number of people infected with HIV/AIDS. It also has more than 30 000 species of plants and many of these have a long tradition of medicinal use. It is highly likely that the treatment for HIV will come from this traditional knowledge. The need for effective preventative and therapeutic agents for HIV remains an urgent global priority. The aim of this study was to screen selected South African medicinal plants for anti-HIV activi

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Ncube, Bhekumthetho. "Seasonal pharmacological and phytochemical properties of medicinal bulbs." Thesis, 2010. http://hdl.handle.net/10413/8585.

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Medicinal bulbs form part of the diversified flora in South Africa. The plants are used extensively in South African traditional medicine in the treatment of various ailments. Due to the ever-increasing demand and the unrestricted collection of medicinal plants from the wild, many of these slow growing bulbous plant species are driven into over-exploitation and extinction. The main parts collected for use are the underground bulbs, leading to the destructive harvesting of the whole plant. This form of plant harvesting poses threats to the long term sustainability of these plant resources from

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Steenkamp, P. A. "Chemical analysis of medicinal and poisonous plants of forensic importance in South Africa." Thesis, 2014. http://hdl.handle.net/10210/12377.

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Ph.D. (Chemistry)<br>The Forensic Chemistry Laboratory of Johannesburg (FCL JHB) is tasked with the chemical analysis of a variety of samples to assist in determining the cause of death where unnatural cause is suspected. Some of the samples submitted to the laboratory have a herbal or muti connotation, but a large portion of these cases turn out to have no herbal components present as only pharmaceutical or agricultural products are detected in these samples. This study combined, for the first time, forensic investigation, chemistry and botany to create a unique platform needed for the identi

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Hartzell, James Francis. "Response of the endangered medicinal plant : Siphonochilus aethiopicus (Schweif) B.L. Burt. to agronomic practices." Thesis, 2011. http://hdl.handle.net/10413/10037.

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This study examines field cropping constraints for domestication of an endangered, wild medicinal plant, Siphonochilus aethiopicus, (Schweif.) B.L. Burt. Extensive literature review and careful observations of plant growth behavior during two years of crop trials overturned several long-held but erroneous claims that have consistently appeared in the scholarly literature, and revealed previously undocumented plant growth characteristics. S. aethiopicus (Schweif.) B.L. Burt. is a rhizomatous corm, not a rhizome. Field growth observations demonstrated clearly that the false stem and leaves grow

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