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1

HIGASHIMURA, Toshinobu. "Medium-Molecular Weight Molecules: A New Perspective in Polymer Science." Kobunshi 46, no. 10 (1997): 737. http://dx.doi.org/10.1295/kobunshi.46.737.

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Manuel Benítez, Sánchez, Barrero Sergio, Da Silva Maria R, Martinez Carlos, Tirado Guillermo Manuel, and Cruz Sonia. "Elimination of Medium/High Molecular Weight Solutes. Comparison of High Flow Hemodialysis with Extended Hemodialysis." Journal of Clinical Nephrology 8, no. 2 (2024): 066–75. http://dx.doi.org/10.29328/journal.jcn.1001129.

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Introduction: Post-dilution online hemodiafiltration is the most efficient extracorporeal depurative treatment of CKD. Recently a new type of membrane has been developed, with a higher cut-off point also called a medium cut-off point, which has the capacity to eliminate higher molecular weight molecules in hemodialysis. The hemodialysis performed with these membranes has been called “Expanded Hemodialysis”. Objective: Compare the purifying efficacy of medium and high molecular weight molecules in patients dialyzed with high-flux hemodialysis, VitaPES 210HF, and with patients treated with expan
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Sashnina, L. Yu, Yu Yu Vladimirova, G. V. Nikonenko, and T. G. Ermolova. "DYNAMICS OF MEDIUM-WEIGHT MOLECULES IN SOWS AT GESTATION PERIOD." Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine 59, no. 1 (2023): 99–103. http://dx.doi.org/10.52368/2078-0109-2023-59-1-99-103.

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The article demonstrates the material on studying the medium-weight molecules at wavelengths of 238, 254, 266, 280 nm, and the assessment of the endogenous intoxication severity in sows at different gestation periods. The maximum severity of the manifestation of physiological endotoxicosis on the days 38-40 of gestation was revealed, accompanied by an increase in the level of medium-weight molecules, the ratio of their fractions and the index of endogenous intoxication, followed by a decrease in the degree of intoxication by days 75-80 of gestation.
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Chow, B. P. C., E. A. Shaffer, and H. G. Parsons. "Absorption of triglycerides in the absence of lipase." Canadian Journal of Physiology and Pharmacology 68, no. 4 (1990): 519–23. http://dx.doi.org/10.1139/y90-074.

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Medium chain triglycerides are considered to be readily absorbed intact in the absence of pancreatic lipase, unlike long chain triglycerides. Commercial medium chain triglyceride oils comprise various medium chain fatty acids from 6 to 12 carbons in length resulting in triglyceride molecules of different sizes and molecular weights. The effect of molecular weight and hence fatty acid chain length on the efficiency of intact medium chain triglyceride absorption is unknown. Therefore, this study measured, using a single-pass marker perfusion technique, intestinal jejunum absorption of five mediu
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Prokofieva, T. V., O. S. Polunina, E. A. Polunina, I. V. Sevostyanova, and P. N. Voronina. "Assessment of endogenous intoxication based on the study of medium and low molecular weight substances in patients with myocardial infarction against a background of chronic obstructive pulmonary disease." Meditsinskiy sovet = Medical Council, no. 17 (October 15, 2022): 106–15. http://dx.doi.org/10.21518/2079-701x-2022-16-17-106-115.

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Introduction. Frequent comorbidity of chronic obstructive pulmonary disease and myocardial infarction is due to the commonality of a number of etiopathogenetic links and the development of endogenous intoxication syndrome. The convincing markers of endogenous intoxication syndrome are medium and low molecular weight molecules including medium and low molecular weight substances and oligopeptides.Aim. To study the levels of medium and low molecular weight substances in patients with myocardial infarction against the background of chronic obstructive pulmonary disease.Materials and methods. 225
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6

Nicastro, Gloria, Louise Mary Black, Paolo Ravarino, et al. "Controlled Hydrolysis of Odorants Schiff Bases in Low-Molecular-Weight Gels." International Journal of Molecular Sciences 23, no. 6 (2022): 3105. http://dx.doi.org/10.3390/ijms23063105.

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Imines or Schiff bases (SB) are formed by the condensation of an aldehyde or a ketone with a primary amine, with the removal of a water molecule. Schiff bases are central molecules in several biological processes for their ability to form and cleave by small variation of the medium. We report here the controlled hydrolysis of four SBs that may be applied in the fragrance industry, as they are profragrances all containing odorant molecules: methyl anthranilate as primary amine, and four aldehydes (cyclamal, helional, hydroxycitronellal and triplal) that are very volatile odorants. The SB stabil
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Semenova, N. V., O. A. Nikitina, E. A. Novikova, et al. "Endogenous intoxication indicators in uncomplicated pregnancy. Medium-weight molecules and lipid peroxidation products." Bulletin of Experimental Biology and Medicine 178, no. 11 (2024): 605–9. https://doi.org/10.47056/0365-9615-2024-178-11-605-609.

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8

TAHIR, LUBNA, MUHAMMAD ISHTIAQ ALI, MUHAMMAD ZIA, NAIMA ATIQ, FARIHA HASAN, and SAFIA AHMED. "Production and Characterization of Esterase in Lantinus tigrinus for Degradation of Polystyrene." Polish Journal of Microbiology 62, no. 1 (2013): 101–8. http://dx.doi.org/10.33073/pjm-2013-015.

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Polystyrene is considered stable to biological degradation. Lantinus tigrinus isolated from wood sample produced esterase in growth medium under normal conditions. However, acidic medium, 37 degrees C temperature, presence of tween 80; and urea and yeast extract in mineral salt medium enhance the production of esterase and specific activity. Purified esterase was active at broad pH range and 45 degrees C. FTIR analysis confirmed that esterase produced by Lantinus tigrinus effectively degraded polystyrene film and broke macromolecules down to non-toxic molecules. This study concludes that the p
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9

Yamamoto, Mayumi, Yuki Fujimoto, Shino Hayashi, and Seiichi Hashida. "A study of high-, middle- and low-molecular weight adiponectin in urine as a surrogate marker for early diabetic nephropathy using ultrasensitive immune complex transfer enzyme immunoassay." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 55, no. 5 (2018): 525–34. http://dx.doi.org/10.1177/0004563217748681.

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Background For the early identification of patients at risk of developing diabetic nephropathy, we have developed an ultrasensitive immune complex transfer enzyme immunoassay to measure adiponectin in urine. Methods We developed immune complex transfer enzyme immunoassay for adiponectin and measured urinary adiponectin from 70 healthy subjects, 35 obese non-diabetic subjects and 20 patients with diabetes. Results The urinary adiponectin concentrations in patients with diabetes (3.3 ± 10.7 ng/mg creatinine) were significantly higher than those in obese subjects (0.54 ± 0.44; P < 0.01) and he
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10

Sedláček, Jan, and Jiří Vohlídal. "Controlled and Living Polymerizations Induced with Rhodium Catalysts. A Review." Collection of Czechoslovak Chemical Communications 68, no. 10 (2003): 1745–90. http://dx.doi.org/10.1135/cccc20031745.

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In the last fifteen years, a large variety of specialty polymers of diverse chemical structure and functionality have been synthesized with the rhodium-based catalysts. The high tolerance to the reaction medium and functional groups of monomers, as well as ability to control various structure features of the polymer formed are typical properties of these catalysts. In addition, some rhodium catalysts can be anchored to inorganic or organic supports or dissolved in ionic liquids to form heterophase polymerization systems, which opens the way to pure, well-defined polymers free of the catalyst r
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11

Holyavka, M. G., and V. G. Artyukhov. "Optimization of a Method for Ficin Immobilization Using Glutaraldehyde." Biotekhnologiya 36, no. 5 (2020): 81–88. http://dx.doi.org/10.21519/0234-2758-2020-36-5-81-88.

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Ficin was covalently immobilized on an acid-soluble matrix of medium (200 kDa) and high molecular weight (350 kDa) chitosans. The enzyme molecules were immobilized in a protein film and copolymerized with glutaraldehyde. The optimal ratio of protein content, total activity and specific activity was observed as a result of ficin covalent immobilization on a matrix of medium-molecular chitosan with 15% glutaraldehyde and high-molecular chitosan with 10% glutaraldehyde. The obtained biocatalysts are promising for industrial applications. ficin, chitosan, glutaraldehyde, covalent immobilization. T
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12

Shashkina, Sof'ya Sergeyevna, Nadezhda Pavlovna Tiguntceva, and Sergey Nikolayevich Evstaf'ev. "THERMOCHEMICAL CONVERSION OF DIOXANLIGNIN OF WHEAT STRAW IN SUB/SUPERCRITICAL DIMETHYL CARBONATE MEDIUM." chemistry of plant raw material, no. 4 (December 15, 2023): 119–26. http://dx.doi.org/10.14258/jcprm.20230412512.

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The aim of this work was to study the conversion processes of dioxanlignin of wheat straw in sub/supercritical dimethyl carbonate medium. The experiment was performed in autoclave in a temperature range from 200 to 350 °С. The low-molecular-weight products were extracted from liquid fraction using hexane. GC-MS was used to analyze their composition. The solid products were analyzed by IR-spectroscopy method. The low-molecular-weight products consist of esters, aldehydes, ketones and alkyl aromatic compounds. Thirty-four compounds were identified by GC-MS, including 12 compounds С6–С3, i.e. str
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13

Stanishevskaya, Olga, Yulia Silyukova, Nikolai Pleshanov, and Anton Kurochkin. "Role of Mono- and Disaccharide Combination in Cryoprotective Medium for Rooster Semen to Ensure Cryoresistance of Spermatozoa." Molecules 26, no. 19 (2021): 5920. http://dx.doi.org/10.3390/molecules26195920.

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The combination of saccharides in the composition of a cryopreservation medium may represent a promising method for the preservation of the reproductive cells of male birds. In the current study, cryoprotective media with a combined composition of mono- and di-saccharides were developed. The degree of penetration of reducing saccharide molecules (maltose—Mal20 medium) and non-reducing disaccharide molecules (trehalose—Treh20 medium) from the cryoprotective medium into the cytosol of rooster spermatozoa was studied. LCM control media without disaccharides were used as the control. The number of
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14

Pisani, Silvia, Rossella Dorati, Ida Genta, Enrica Chiesa, Tiziana Modena, and Bice Conti. "High Efficiency Vibrational Technology (HEVT) for Cell Encapsulation in Polymeric Microcapsules." Pharmaceutics 12, no. 5 (2020): 469. http://dx.doi.org/10.3390/pharmaceutics12050469.

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Poly(methyl-methacrylate) (PMMA) is a biocompatible and non-biodegradable polymer widely used as biomedical material. PMMA microcapsules with suitable dimension and porosity range are proposed to encapsulate live cells useful for tissue regeneration purposes. The aim of this work was to evaluate the feasibility of producing cell-loaded PMMA microcapsules through “high efficiency vibrational technology” (HEVT). Preliminary studies were conducted to set up the process parameters for PMMA microcapsules production and human dermal fibroblast, used as cell model, were encapsulated in shell/core mic
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15

Aleksieieva, N. G. "Advantages of expanded hemodialysis (HDx) over standard hemodialysis." Ukrainian Journal of Nephrology and Dialysis, no. 4(64) (December 23, 2019): 56–61. http://dx.doi.org/10.31450/ukrjnd.4(64).2019.08.

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Chronic kidney disease leads to the accumulation of a wide range of uremic toxins. Negative effects of uremic toxins are most likely due to the combined effects of many uremic solutes, including small molecules, middle molecules, and soluble protein-linked substances. Large and medium-sized molecules are directly associated with chronic inflammation and adverse effects, including major cardiovascular risks and consequently poor prognosis.
 Recent advances in chemical composition and new production techniques led to improved biocompatibility and selective permeability of dialysis membranes
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16

Ng, Yoke Mooi, Paolo Coghi, Jerome P. L. Ng, Fayaz Ali, Vincent Kam Wai Wong, and Carmine Coluccini. "Synthesis and Coordination Properties of a Water-Soluble Material by Cross-Linking Low Molecular Weight Polyethyleneimine with Armed Cyclotriveratrilene." Polymers 13, no. 23 (2021): 4133. http://dx.doi.org/10.3390/polym13234133.

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In this study, a full organic and water-soluble material was synthesized by coupling low molecular weight polyethylenimine (PEI-800) with cyclotriveratrilene (CTV). The water-soluble cross-linked polymer contains hydrophobic holes with a high coordination capability towards different organic drug molecules. The coordinating capability towards hydrophilic drugs (doxorubicin, gatifloxacin and sinomenine) and hydrophobic drugs (camptothecin and celastrol) was analyzed in an aqueous medium by using NMR, UV-Vis and emission spectroscopies. The coordination of drug molecules with the armed CTV unit
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17

Kopylova, Svetlana V., Anastasiya A. Anashkina, and Elena I. Erlykina. "Physiological Effects of Using a Complex Preparation Based on Royal Jelly and Propolis in Pulmonary Oedema in Rats." Journal of Medical and Biological Research, no. 1 (February 10, 2021): 16–24. http://dx.doi.org/10.37482/2687-1491-z039.

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This paper aimed to study the physiological effects of inhalation therapy using Apingalin (based on royal jelly and propolis) in experimental pulmonary oedema in rats. The research involved 120 Wistar albino rats that were divided into 3 groups: intact; control (with pulmonary oedema induced by 0.5 mg/kg adrenaline); experimental (with induced pulmonary oedema followed by a 10-minute inhalation of Apingalin during the course of 10 days). In the blood serum of the control group of rats, a decrease in the activity of aspartate transaminase (AST) and alanine transaminase (ALT) was detected; the r
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18

Page, A. P., and R. M. Maizels. "Biosynthesis and glycosylation of serine/threonine-rich secreted proteins from Toxocara canis larvae." Parasitology 105, no. 2 (1992): 297–308. http://dx.doi.org/10.1017/s0031182000074229.

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SUMMARYToxocara canis infective stage larvae continually produce excretory–secretory (TES) glycoproteins in long-term in vitro culture. The kinetics of synthesis and secretion were studied by metabolic labelling with radioactive [35S]methionine, [14C]serine and [14C]threonine. Maximal incorporation rates required overnight pre-incubation of parasites in medium depleted of the appropriate amino acid. Larvae rapidly incorporated isotope into their somatic tissues, but there was a minimum delay of 10 h before secretion of labelled antigens. Labelling with [14C]serine and [14C]threonine demonstrat
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19

Tarasova, I. A., K. B. Gurieva, E. A. Tarasova, S. L. Beletskiy, and N. A. Khaba. "Study of the fractional composition of wheat proteins and macaroni products during storage." Tovaroved prodovolstvennykh tovarov (Commodity specialist of food products), no. 10 (September 12, 2021): 776–83. http://dx.doi.org/10.33920/igt-01-2110-09.

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The results of the molecular weight distribution of wheat proteins and macaroni products are presented. The fractional composition of proteins was determined by gel permeation chromatography on a Knauer Smartline chromatograph; preliminary hydrolysis was carried out using a thermostable bacterium α-Amylase, then it was centrifuged, filtered through a Teflon filter, and the size of protein molecules was determined by photometric detection at a wavelength of 280 nm. It has been shown that the main protein fraction in both wheat and macaroni products is a low molecular weight fraction up to 3 kD
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20

Felfernig, M., S. Virmani, M. Weintraud, et al. "Molecular weight of Hydroxyethyl Starch Molecules influences Coagulation Profile measured by thrombelastography." Journal of The Royal Naval Medical Service 94, no. 1 (2008): 7–13. http://dx.doi.org/10.1136/jrnms-94-7.

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SummaryBackgroundThe consensus about the ideal intravenous fluid in trauma patients remains open. However, hypertonic saline and hydroxyethyl starch (HES) seems to have advantages in terms of immuno-modulatory and haemodynamic effects. Nevertheless clotting abnormalities are frequently reported in association with the use of HES. We investigated the influence of light, medium and heavy molecular weight (MW) hydroxyethyl starch (HES) on coagulation in 29 healthy subjects.MethodsRinger’s lactate (RL) served as a control solution. Thrombelastography using Haemoscope’s Thrombelastograph® (TEG®) he
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Alshanqiti, Khadijah. "Date Seed Extract as Green Corrosion Inhibitor for Steel in Hydrochloric Medium." Issue 1 6, no. 1 (2023): 7–13. http://dx.doi.org/10.48103/jjeci622023.

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The date seed extract is considered an effective and environmentally friendly corrosion inhibitor. In this study,the ability to inhibit corrosion of steel in an acidic medium was tested by measuring weight loss, potentiodynamic polarisation, scanning electron microscope techniques, and Fourier Transform infrared spectroscopy. Depending on weight loss, it was observed that inhibition efficiency increased with inhibitor concentration, while the corrosion rate decreased. The maximum inhibition efficiency was 93% for 0.6g/L in0.5M HCl. The results from the polarization curves showed that the extra
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Puttawibul, Puttiporn, Soottawat Benjakul, and Jirut Meesane. "Freeze-Thawed Hybridized Preparation with Biomimetic Self-Assembly for a Polyvinyl Alcohol/Collagen Hydrogel Created for Meniscus Tissue Engineering." Journal of Biomimetics, Biomaterials and Biomedical Engineering 21 (August 2014): 17–33. http://dx.doi.org/10.4028/www.scientific.net/jbbbe.21.17.

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Freeze-thawed hybridized preparation and the biomimetic self-assembly technique were used to fabricate hydrogel as tissue engineered scaffolds for meniscus tissue. Because of the advantages of both techniques, they were hybridized together as an interesting preparation for hydrogel. Three molecular weights (high, medium, and low) of PVA were prepared in a biomimetic solution before formation into hydrogel by freeze-thawing. The most suitable molecular weight PVA for hydrogel formation was chosen to be mixed with collagen. PVA, PVA/collagen, and collagen were prepared in biomimetic solutions an
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23

Journal, Baghdad Science. "Production and Extraction of Siderophores-Catecholate- from -MDR-Acinetobacter baumannii." Baghdad Science Journal 14, no. 2 (2017): 356–62. http://dx.doi.org/10.21123/bsj.14.2.356-362.

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Siderophores are low molecular weight organic compounds produced by microorganisms growing under low iron concentration.In this study we describe the detection, production and extraction of siderophores secreted by Acinetobacter baumannii (Multiple-drug resistant ) pathogens. One hundered twenty Gram –negative non lactose fermenter bacilli isolates have been collected from three hospitals at Baghdad city over three months. Primary identification of these isolates is performed by standard diagnostic methods (biochemical tests and API 20 NE); 19 clinical isolates of A. baumannii are cultured on
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Blokhina, O., L. Kot, Ie Torgalo, and K. Dvorshchenko. "C-reactive protein and medium weight molecules concentration in serum of rats under conditions of carrageenan-induced inflammation and prolonged prophylactic administration of chondroitin sulfate." Bulletin of Taras Shevchenko National University of Kyiv. Series: Problems of Physiological Functions Regulation 26, no. 1 (2019): 17–21. http://dx.doi.org/10.17721/1728_2624.2019.26.17-21.

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The aim of the work was to investigate the preventive effect of Chondroitin Sulfate on the concentration of C-reactive protein and medium weight molecules in blood serum of rats at local inflammation of the hind limb. The studies were conducted on white non-linear, sexually mature male rats weighing 180–240 g, in compliance with the general ethical principles of experiments on animals. All animals were divided into four experimental groups. The first group – control: animals sub-planar injected 0.1 ml of 0.9 % NaCl solution into the posterior right limb. The second group – animals received a t
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Aresta, Antonella, Pietro Cotugno, Nicoletta De Vietro, et al. "Volatile Organic Compounds, Indole, and Biogenic Amines Assessment in Two Mediterranean Irciniidae (Porifera, Demospongiae)." Marine Drugs 19, no. 12 (2021): 711. http://dx.doi.org/10.3390/md19120711.

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Solid phase microextraction (SPME) coupled to gas chromatography-mass spectrometry (GC-MS) was employed for the headspace determination of the volatile organic fraction emitted by two of the most common Mediterranean demosponges, Ircinia variabilis and Sarcotragus spinosulus, and of indole and some biogenic amines released by sponges in an aqueous medium. A total of 50/30 µm divinylbenzene/carboxen/polydimethylsiloxane and 75 µm carboxen/polydimethylsiloxane fibers were used for the headspace extraction of low molecular weight sulfur compounds from a hermetically sealed vial containing sponge
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Bekjanova, Olga, and Adizov Miraziz. "The role of middle-weight molecules and the detoxication activity of mixed saliva albumin in the development of periodontal pathology in oil refinery workers." E3S Web of Conferences 413 (2023): 03029. http://dx.doi.org/10.1051/e3sconf/202341303029.

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The study evaluated the biochemical effects of chronic exposure to the oil refining industry on medium-weight molecules and the detoxifying activity of mixed saliva albumin in the development of periodontal pathology in oil refinery workers in the mixed saliva of workers in hazardous production. The workers of the main specialties of the Bukhara oil refinery were examined.
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Ibaeva, Khadizhat Alviyevna, Arnold Alekseevich Shamilov, Natalia Nikolaevna Stepanova, and Ekaterina Robertovna Garcia. "COMPARATIVE STUDY OF PHYSIC-CHEMICAL PROPERTIES OF POLYSACCHARIDES SELECTED FROM FRUITS OF VACCINIUM ARCTOSTAPHYLOS L. AND VACCINIUM MYRTILLUS L." chemistry of plant raw material, no. 4 (November 6, 2024): 89–99. https://doi.org/10.14258/jcprm.20240414259.

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In medicine we use natural high-molecular weight substances as individual or as secondary agents in complex preparations and as transport agents for the main substances. Polysaccharides as plant polymers may be as these agents and we need to know their physical and chemical features in the development of the pharmaceutical substances of plant origin. Aim. Investigation of physical and chemical features of polysaccharides from fruits of Vaccinium arctostaphylos L. and Vaccinium myrtillus L. For this aim, we solved the following tasks: isolate water-soluble polysaccharides (WSPS) and pectinic su
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Sukumaran, Monikandon, and Kesavan Devarayan. "Surface Protection of Steel by Adsorption of Milletia Pinnata Extract." Material Science Research India 13, no. 2 (2016): 101–5. http://dx.doi.org/10.13005/msri/130206.

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Steel corrosion inhibition in acidic and alkaline medium by ethanolic extract of Milletia pinnata is described in this study. The inhibitive behavior of the inhibitor is evaluated by weight loss measurements, adsorption isotherms, and thermochemical parameters. The inhibitor exhibited a maximum of 87% and 90.5% inhibition efficiency against steel corrosion in 0.5 M NaOH and 1.0 M H2SO4, respectively. The weight loss linearly fit to Langmuir adsorption isotherm with correlation coefficient value close to unity. The thermochemical parameters indicated for predominant physical adsorption of the i
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Syniachenko, O. V., M. V. Yermolaieva, T. Yu Aliieva, K. V. Lientsova, S. M. Verzilov, and T. Yu Syniachenko. "Level of middle mass molecules in synovial fluid of patients with rheumatoid arthritis." TRAUMA 21, no. 6 (2021): 21–26. http://dx.doi.org/10.22141/1608-1706.6.21.2020.223884.

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Background. Due to direct contact with cartilage, bone surface and synoviocytes, the study of synovial fluid in rheumatoid arthritis has a great diagnostic value, and changes in its indicators clearly correlate with the data of the morphological study of the affected articular tissues. In the synovial fluid of rheumatoid arthritis patients, protein substances of diffe-rent molecular mass and enzymes involved in the destruction of cartilage, tendons and ligaments are accumulated. At the same time, there are no reliable differential diagnostic biomarkers of synovial fluid in joint pathology. The
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Gaidai, G. "PP-058 Medium molecular weight molecules contents in pregnant women amniotic fluid at different terms of gestation as markers of intoxication." International Journal of Infectious Diseases 15 (July 2011): S61. http://dx.doi.org/10.1016/s1201-9712(11)60211-7.

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31

Prusskiy, F. O. "Cardiovascular complications in hemodialysis patients: current approaches to prolong and improve quality of patients’ life." Ukrainian Journal of Nephrology and Dialysis, no. 3(63) (September 4, 2019): 53–61. http://dx.doi.org/10.31450/ukrjnd.3(63).2019.08.

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Cardiovascular complications are a leading cause of morbidity and mortality in dialysis patients. Cardiovascular mortality is more than 40% of the total mortality in this cohort of patients. Recently, there has been an increase in publications on the role of uremic toxins, including “middle molecules”, in the development and progression of cardiovascular complications in dialysis patients.
 Conventional low-flux (LF) hemodialysis well removes small molecular weight uremic toxins not bound with protein. Evidence for the role of "middle molecules" in the development of many complications, i
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Fukami, Takanori, Seiya Hiyajyo, Shuta Tahara, and Chitoshi Yasuda. "Thermal Properties and Crystal Structure of BaC4H4O6 Single Crystals." International Journal of Chemistry 9, no. 1 (2016): 30. http://dx.doi.org/10.5539/ijc.v9n1p30.

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Single crystals of barium L-tartrate, BaC4H4O6, were grown at 308 K by a gel method using silica gel as the growth medium. Differential scanning calorimetry, thermogravimetric-differential thermal analysis, and X-ray diffraction measurements were performed on the single crystals. The space group symmetry (orthorhombic, P212121) and structural parameters were determined at room temperature. The crystal structure consisted of BaO9 polyhedra, C4H4O6 molecules, and zig-zag hydrogen-bonded chains along the a- and c-axes linked by O–H···O and C–H···O hydrogen bonds between adjacent molecules. Weight
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33

Prokofyeva, T. V., O. S. Polunina, L. P. Voronina, E. A. Polunina, and I. V. Sevostyanova. "Prognostic value of molecules of average mass in patients with chronic obstructive pulmonary disease." Acta Biomedica Scientifica 7, no. 6 (2022): 34–44. http://dx.doi.org/10.29413/abs.2022-7.6.4.

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Background. Chronic obstructive pulmonary disease is a socially significant disease affecting patient’s quality of life. Assessment of endogenous intoxication in patients with chronic obstructive pulmonary disease will allow to understand pathogenetic features of different phenotypes of this disease, which can be taken into account when predicting its course.The aim of the study. To determine the prognostic value of levels of mediumand low-molecular-weight substances and oligopeptides in patients with chronic obstructive pulmonary disease.Materials and methods. One hundred and four patients wi
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Fukami, Takanori, and Shuta Tahara. "Structural and Thermal Investigations of L-CuC4H4O6·3H2O and DL-CuC4H4O6·2H2O Single Crystals." International Journal of Chemistry 13, no. 1 (2021): 38. http://dx.doi.org/10.5539/ijc.v13n1p38.

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Copper(II) L-tartrate trihydrate, L-CuC4H4O6·3H2O, and copper(II) DL-tartrate dihydrate, DL-CuC4H4O6·2H2O, crystals were grown at room temperature by the gel method using silica gels as the growth medium. Differential scanning calorimetry, thermogravimetric-differential thermal analysis, and X-ray diffraction measurements were performed on both crystals. The space group symmetries (monoclinic P21 and P21/c) and structural parameters of the crystals were determined at room temperature and at 114 K. Both structures consisted of slightly distorted CuO6 octahedra, C4H4O6 and
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35

Thusnavis, G. Rexin, T. V. Archana, K. P. Vinod Kumar, and M. Sankara Narayanan Pillai. "Seed Extract of Dypsis lutescens as Ecofriendly Corrosion Inhibitor for Mild Steel in Hydrochloric Acid Medium." International Journal of ChemTech Research 13, no. 1 (2020): 149–58. http://dx.doi.org/10.20902/ijctr.2019.130118.

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The seed extract of Dypsis lutescens, had been analyzed for mild steel corrosion inhibition in acid medium with weight loss, thermodynamic, adsorption and electrochemical parameters. The results reflected that the extract is a potential corrosion inhibitor. IR spectra and SEM photographs recorded for functional group and surface modification analysis of mild steel, were agreeing with other parameters. Entire study revealed that the inhibitor works through adsorption of its molecules over the mild steel. From this study it is inferred that the seed extract of D. lutescens is an efficient, eco-f
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36

Shamilov, Arnol'd Alekseyevich, Valentina Nikolayevna Bubenchikova, Nataliya Nikolayevna Stepanova, and Ekaterina Robertovna Garsiya. "COMPARATIVE STUDY OF PHYSIC-CHEMICAL PROPERTIES OF POLYSACCHARIDES SELECTED FROM PRUNELLA SPP." chemistry of plant raw material, no. 4 (December 15, 2023): 89–98. http://dx.doi.org/10.14258/jcprm.20230412174.

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Natural high molecular weight compounds are used in medicine separately and in complex drugs as concomitant substance and as transport substances for the main compounds. Polysaccharides are plant polymers and its physic-chemical properties are useful in the development of pharmaceutical substances of plant origin. The aim of this study is investigation of physic-chemical properties of polysaccharides selected from Prunella spp. herb. For this aim, we solved the following tasks: estimate medium molecular weight of water-soluble polysaccharides (WSPS) and pectinic substances (PS) by viscosimeter
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37

Fukami, Takanori, Shuta Tahara, and Arbi Dimyati. "Crystal Structures and Thermal Properties of L-MnC4H4O6•2H2O and DL-MnC4H4O6•2H2O." International Journal of Chemistry 12, no. 1 (2019): 78. http://dx.doi.org/10.5539/ijc.v12n1p78.

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Manganese L-tartrate dihydrate, L-MnC4H4O6·2H2O, and manganese DL-tartrate dihydrate, DL-MnC4H4O6·2H2O, crystals were grown at room temperature by the gel method using silica gels as the growth medium. Differential scanning calorimetry, thermogravimetric-differential thermal analysis, and X-ray diffraction measurements were performed on both crystals. The space group symmetries (monoclinic P21 and P2/c) and structural parameters of the crystals were determined at room temperature. Both structures consisted of slightly distorted MnO6 octahedra, C4H4O6 and H2O molecules, an
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38

Beaulieu, Lucie, Michel Desbiens, Jacinthe Thibodeau, and Sharon Thibault. "Pelagic fish hydrolysates as peptones for bacterial culture media." Canadian Journal of Microbiology 55, no. 11 (2009): 1240–49. http://dx.doi.org/10.1139/w09-084.

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For several years in the Quebec fisheries’ industry,landings of pelagic fish have been calculated at over 4000 tons. These under-exploited species, rich in lipids and proteins, could be used in valuable new products. In the present study, hydrolysates of mackerel and herring were produced and utilized as sources of peptones in the formulation of new bacterial culture media. The molecular weight distribution analysis showed that molecules present in the hydrolysates were lower than 1300 Da for herring, and lower than 930 Da for mackerel. The formulated media were compared with reference media u
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39

CHAN, ELAINE R., LIN C. HO, and SHARON C. GLOTZER. "MESOSCALE COMPUTER SIMULATIONS OF POLYMER-TETHERED ORGANIC/INORGANIC NANOCUBE SELF-ASSEMBLY." International Journal of Modern Physics C 20, no. 09 (2009): 1443–56. http://dx.doi.org/10.1142/s0129183109014503.

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A molecular simulation study of the mesoscale self-assembly of tethered nanoparticles having a cubic geometry is presented. Minimal models of the tethered nanocubes are developed to represent a polyhedral oligomeric silsesquioxane (POSS) molecule with polymeric substituents. The models incorporate some of the essential structural features and interaction specificity of POSS molecules, and facilitate access to the long length and timescales pertinent to the assembly process while foregoing atomistic detail. The types of self-assembled nanostructures formed by the tethered nanocubes in solution
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40

Bevzo, V. V. "Rat Endogenous Intoxication Level under Experimental Nephropathy and Reduced Glutathione Application." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 6, no. 5 (2021): 63–68. http://dx.doi.org/10.26693/jmbs06.05.063.

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The purpose of the study, therefore, was to investigate the content of substances of low and medium molecular weight, total and tyrosine-containing peptides and to assess the level of endogenous intoxication of the rat organism under conditions of experimental nephropathy and the use of reduced glutathione. Materials and methods. The experiment was performed on nonlinear white rats weighing 160-180 g. The animals were in a vivarium with a constant temperature (18-22°C), relative humidity (50-55%) in individual exchange cells in the formed groups, on a constant balanced mode of a diet with free
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41

Khodov, Ilya A., Konstantin V. Belov, Michael A. Krestyaninov, Alexey A. Dyshin, and Michael G. Kiselev. "Investigation of the Spatial Structure of Flufenamic Acid in Supercritical Carbon Dioxide Media via 2D NOESY." Materials 16, no. 4 (2023): 1524. http://dx.doi.org/10.3390/ma16041524.

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The search for new forms of already known drug compounds is an urgent problem of high relevance as more potent drugs with fewer side effects are needed. The trifluoromethyl group in flufenamic acid renders its chemical structure differently from other fenamates. This modification is responsible for a large number of conformational polymorphs. Therefore, flufenamic acid is a promising structural modification of well-known drug molecules. An effective approach in this field is micronization, employing “green” supercritical fluid technologies. This research raises some key questions to be answere
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42

Pieniazek, Anna, Joanna Bernasinska-Slomczewska, and Lukasz Gwozdzinski. "Uremic Toxins and Their Relation with Oxidative Stress Induced in Patients with CKD." International Journal of Molecular Sciences 22, no. 12 (2021): 6196. http://dx.doi.org/10.3390/ijms22126196.

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The presence of toxins is believed to be a major factor in the development of uremia in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Uremic toxins have been divided into 3 groups: small substances dissolved in water, medium molecules: peptides and low molecular weight proteins, and protein-bound toxins. One of the earliest known toxins is urea, the concentration of which was considered negligible in CKD patients. However, subsequent studies have shown that it can lead to increased production of reactive oxygen species (ROS), and induce insulin resistance in vi
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43

Kawanishi, Hideki. "Middle Molecular Uremic Toxin and Blood Purification Therapy." Journal of Clinical Medicine 13, no. 3 (2024): 647. http://dx.doi.org/10.3390/jcm13030647.

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The purpose of blood purification therapy is to remove uremic toxins, and middle molecules (MMs) are a specific target. An MM is defined as a solute that passes through the glomerulus with a molecular weight in the range of 0.5–58 kDa, and new classifications of “small-middle 0.5–15 kDa,” “medium-middle 15–25 kDa,” and “large-middle 25–58 kDa” were proposed. In Japan, the removal of α1-microglobulin (αMG) in the large-middle range has been the focus, but a new theory of removal has been developed, emphasizing the antioxidant effect of αMG as a physiological function. Clinical proof of this mec
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44

Bouziges, F., P. Simon-Assmann, C. Leberquier, K. Haffen, and M. Kedinger. "Glycosaminoglycan expression in intestinal epithelial skin-fibroblastic cell cocultures. Fibroblastic cell-mediated effects of glucocorticoids." Journal of Cell Science 92, no. 4 (1989): 679–85. http://dx.doi.org/10.1242/jcs.92.4.679.

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The nature and distribution of newly synthesized glycosaminoglycans (GAGs) were studied in foetal rat skin fibroblasts, in rat intestinal endodermal cells and in cocultures of both cell types. The data show that fibroblasts synthesize and secrete hyaluronic acid (HA), heparan sulphate (HS) and chondroitin sulphate molecules (CS). Our data focus on HA, which is found as two different molecular forms, the smallest hydrodynamic-sized species being mostly recovered within the cell or associated with the cell surface, and the largest one secreted into the medium, whatever the cell type. Endodermal
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45

Bhaskara, Shobha, Sanaulla Pathapalya Fakrudeen, Tegene Desalegn, H. C. Ananda Murthy, and V. Bheemaraju. "Evaluation of Corrosion Inhibition Efficiency of Aluminum Alloy 2024 by Diaminostilbene and Azobenzene Schiff Bases in 1 M Hydrochloric Acid." International Journal of Corrosion 2021 (October 21, 2021): 1–20. http://dx.doi.org/10.1155/2021/5869915.

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The Schiff base compounds N,N ′ -bis(salicylidine)-4,4 ′ –diaminostilbene(SDS) and N,N ′ -bis(salicylidine)-4,4 ′ -diamino azobenzene(SDA) were synthesized, and their molecular structure was determined by FT-IR and 1H NMR. The corrosion inhibitions of Schiff base compounds on aluminum alloy 2024 in 1 M hydrochloric acid were evaluated by potentiodynamic polarization, impedance techniques, weight loss method, and scanning electron microscopic technique. The potentiodynamic polarization (PDP) studies revealed that SDS and SDA compounds acted predominantly as cathodic inhibitors. The electrochemi
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46

Allen, Simon, Adel M. Abuzenadah, Joanna L. Blagg, et al. "Two novel type 2N von Willebrand disease–causing mutations that result in defective factor VIII binding, multimerization, and secretion of von Willebrand factor." Blood 95, no. 6 (2000): 2000–2007. http://dx.doi.org/10.1182/blood.v95.6.2000.

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Abstract Two novel mutations, a T-to-C transition at nucleotide 2612 and a T-to-G transversion at nucleotide 3923 of the von Willebrand factor (vWF) complementary DNA, were detected by analysis of the vWF gene in DNA from members of 2 families with atypical von Willebrand disease. The T2612C transition predicts substitution of cysteine by arginine at amino acid position 788 (C788R), and the T3923G transversion predicts substitution of cysteine by glycine at position 1225 (C1225G) of pre-pro-vWF. The patients homozygous for the C788R and C1225G mutations both had a partial vWF deficiency (0.18
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47

Taiti, Cosimo, Elisa Masi, Vittoria Cicaloni, Vittorio Vinciguerra, Laura Salvini, and Stefania Garzoli. "SPME-GC-MS and PTR-ToF-MS Techniques for the Profiling of the Metabolomic Pattern of VOCs and GC-MS for the Determination of the Cannabinoid Content of Three Cultivars of Cannabis sativa L. Pollen." Molecules 27, no. 24 (2022): 8739. http://dx.doi.org/10.3390/molecules27248739.

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Considering the large number of volatile molecules that characterize Cannabis sativa L., adequate investigation supported by the application of robust and effective analytical methods is essential to better understand the impact of these low- and medium-molecular-weight molecules on the entire phytocomplex. This work aimed to characterize the volatile fraction of the chemical profile of three different cultivars of Cannabis sativa L. pollen, grown in Italy, which were thoroughly investigated by the application of two complementary techniques: SPME-GC-MS and PTR-ToF-MS. Furthermore, in order to
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48

Mavromatidis, Konstantinos, Irini Kalogiannidou, Ploumis Passadakis, and Gkiounai Katzel Axmet. "Efficacy of medium molecular weight toxin clearance in manual mixed online hemodiafiltration vs. pre- and post-dilution online hemodiafiltration and conventional hemodialysis: A crossover observational study." Ukrainian Journal of Nephrology and Dialysis, no. 3(83) (August 18, 2024): 14–24. http://dx.doi.org/10.31450/ukrjnd.3(83).2024.03.

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The effectiveness of various hemodiafiltration (HDF) modes in removing different toxins is not fully understood. The present study aimed to compare the efficacy of manual mixed online HDF with pre-dilution online HDF, post-dilution online HDF, and conventional hemodialysis in clearing medium molecular weight toxins. Methods. This single-center, crossover observational study included 11 patients (7 males, 4 females) aged 48-85 years (mean age 65.2±11.7) with a dialysis vintage of 24-455 months (mean duration 126±123 months), including 10-29 months (mean duration 19.5±6.4) on HDF. The study focu
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49

Pushpa, S. A., P. Goonetilleke, and N. C. Billingham. "Diffusion of Antioxidants in Rubber." Rubber Chemistry and Technology 68, no. 5 (1995): 705–16. http://dx.doi.org/10.5254/1.3538767.

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Abstract Migration of compounding ingredients such as antioxidants is a problem that has been recognized by rubber compounders. The literature is almost void of quantitative data in this area. Therefore an investigation of the diffusion of some commonly used phenolic antioxidants in three different rubber vulcanizates was carried out. The antioxidants were chosen so that they included a wide range of molecular weights as well as structural differences to enable us to study the effect of size and molecular nature on diffusion in the medium of rubber. The effect of crosslink density on diffusion
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50

Tlish, М. M., and Е. К. Popandopulo. "Dynamics of the Antioxidant System and Endogenous Intoxication in Patients Being Treated for Microbial Eczema." Kuban Scientific Medical Bulletin 26, no. 4 (2019): 56–65. http://dx.doi.org/10.25207/1608-6228-2019-26-4-56-65.

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Aim. The paper studies the dynamics of the indicators defi ning the antioxidant system (AOS) and endogenous intoxication in patients with microbial eczema (ME) prior to and following treatment.Materials and methods. The experimental group consisted of patients with ME (n=30) and the control group comprising somatically healthy individuals (n=30). In this study, we determined the components of the antioxidant defence system in blood plasma and erythrocyte suspension, as well as assessed endogenous intoxication.Results. The study revealed an imbalance of indicators refl ecting the severity of ox
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