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Relevant bibliographies by topics / Mefloquine. Malaria

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Dissertations / Theses

Academic literature on the topic 'Mefloquine. Malaria'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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Dissertations / Theses on the topic "Mefloquine. Malaria"

1

Karbwang, J. "Clinical pharmacology of mefloquine." Thesis, University of Liverpool, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234865.

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2

Kitchener, Scott. "Evaluation of safety and adverse effects of mefloquine in the chemoprophylaxis of Malaria in non-immune Australian soldiers /." St. Lucia, Qld, 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16419.pdf.

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3

Holmes, Katelyn. "Cytotoxicity and Functional Toxicity of Mefloquine and the Search for Protective Compounds." Thesis, University of North Texas, 2015. https://digital.library.unt.edu/ark:/67531/metadc801913/.

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Mefloquine hydrochloride is an antimalarial agent that has been used for the past 40 years. Numerous reports of neurological side effects have recently led the FDA to issue a strong warning regarding long-term neurological effects. This warning lead to the U.S. Army’s Special Forces and other components to discontinue its use in July of 2013. Despite reported adverse side effects, mefloquine remains in circulation and is recommended to travelers going to specific Asian countries. Mefloquine has been used as a treatment for those already infected with the malaria parasite (blood concentratio

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4

Langley, Natasha. "Preclinical evaluation of the possible enhancement of the efficacy of anti-malarial drugs by pheroid technology / Natasha Langley." Thesis, North-West University, 2007. http://hdl.handle.net/10394/1521.

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5

Van, Huyssteen Este. "Efficacy enhancement of the antimalarial drugs, mefloquine and artesunate, with PheroidTM technology / E. van Huyssteen." Thesis, North-West University, 2010. http://hdl.handle.net/10394/5050.

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Malaria is currently one of the most imperative parasitic diseases in developing countries. Artesunate has a short half-life, low aqueous solubility and resultant poor and erratic absorption upon oral administration, which translate to low bioavailability. Mefloquine is eliminated slowly with a terminal elimination half-life of approximately 20 days and has neuropsychiatric side effects. Novel drug delivery systems have been utilised to optimise chemotherapy with currently available antimalarial drugs. Pheroid™ technology is a patented drug delivery system which has the ability to capture, tra

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6

Basson, Eldrian. "The prevalence of malaria in Mefloquine hydrochloride - mefliam ® users during the deployment of military forces in Burundi, East Africa." Thesis, Bloemfontein : Central University of Technology, Free State, 2007. http://hdl.handle.net/11462/87.

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Thesis (M. Tech.) - Central University of Technology, Free State, 2007<br>Malaria and the mosquito that induces the disease in humans have hounded the military for decades. Malaria represents one of the most important infectious disease threats to deployed military forces. Malaria in soldiers has a serious economic impact, both in terms of lost productivity and treatment cost for the state. A contingent of South African National Defence Force members has been deployed in Burundi since November 2001, as part of a peacekeeping mission. At the time of the study no information was available regard

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7

Slabbert, Chrizaan. "Evaluation and validation of methods to determine parasitemia in malaria cell cultures / Chrizaan Slabbert." Thesis, North-West University, 2008. http://hdl.handle.net/10394/2332.

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8

Wessels, Johanna Christina. "International pharmacopoeia monographs : antimalarial dosage forms / J.C. Wessels." Thesis, North-West University, 2010. http://hdl.handle.net/10394/4920.

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Malaria is a disease affecting millions of people in 109 malarious countries and territories, causing approximately one million deaths annually. In 2004 one of the parasites causing human malaria, Plasmodium falciparum, was among the leading global causes of death from a single infectious agent, especially in Africa (WHO, 2008:23). Treatment of this disease with single active pharmaceutical ingredients has led to the emergence of resistant P. falciparum parasites, resulting in the most severe form of this illness. Alarmingly, the poor quality of commercially available antimalarial products, es

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9

Ghavami, Maryam. "Antimalarial Agents: New Mechanisms of Actions for Old and New Drugs." Diss., Virginia Tech, 2018. http://hdl.handle.net/10919/96192.

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Worldwide, malaria is one of the deadliest diseases. In 2016 it sickened 216 million people and caused 445,000 deaths. In order to control the spread of this deadly diseases to human, we can either target the mosquito vector (Anopheles gambiae) or the parasite (Plasmodium falciparum). Due to recent emergence of resistance to current insecticides and antimalarial drugs there is a pressing need to discover and develop new agents that engage new targets in these organisms. To circumvent the effect of resistance to pyrethroid insecticides on the efficacy of insecticide treated nets (ITNs), the us

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10

Guimarães, Matheus Murmel. "Utilização de carboidratos e derivados na preparação de grupos conectores para síntese de antimaláricos multifuncionais." reponame:Repositório Institucional da UFPR, 2016. http://hdl.handle.net/1884/45784.

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Orientador : Prof. Dr. Alan Guilherme Gonçalves<br>Coorientador : Prof. Dr. Diogo R. B. Ducatti<br>Coorientador : Prof. Dr. Roberto Pantarolo<br>Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências da Saúde, Programa de Pós-Graduação em Ciências Farmacêuticas. Defesa: Curitiba, 25/02/2016<br>Inclui referências : f. [121-139]<br>Área de concentração: Insumos, medicamentos e correlatos<br>Resumo: Uma doença de longo histórico existencial, a malária é uma parasitose que ainda coloca diversas regiões do mundo em risco, ocasionando milhares de mortes. A Organização Mundial de

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